Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| propionibacterium acnes in capsular bag distension syndrome. | we report a case of capsular bag distension syndrome that developed 6 years after uneventful phacoemulsification with implantation of a foldable, single-piece acrylic intraocular lens (iol) (acrysof ma60bm). slitlamp microscopy revealed a deep anterior chamber with no flare or cells. the posterior capsular bag was distended by a homogeneous milky substance between the back of the iol and the capsular bag. using a pars plana approach, a 23-gauge bimanual capsulotomy and anterior vitrectomy were p ... | 2010 | 20117721 |
| massive ascites as unique sign of shunt infection by propionibacterium acnes. | propionibacterium acnes (p. acnes) has been associated with shunt infection. the signs of infection are mild. we report on a case of p. acnes shunt infection presenting with massive ascites as the unique sign of csf infection. shunt removal, antibiotic therapy and drenaige of ascites were performed with a rapid clinical recovery. | 2010 | 20121383 |
| ifn-gamma is a master regulator of endotoxin shock syndrome in mice primed with heat-killed propionibacterium acnes. | hyper-coagulation, hypothermia, systemic inflammatory responses and shock are major clinical manifestations of endotoxin shock syndrome in human. as previously reported, mice primed with heat-killed propionibacterium acnes are highly susceptible to the action of lps to induce tumour necrosis factor (tnf)-alpha and to that of tnf-alpha to trigger lethal shock. here we investigated the mechanisms underlying the p. acnes-induced sensitization to lps and tnf-alpha and the development of individual s ... | 2010 | 20130231 |
| evaluation of the antibacterial activity of rhapontigenin produced from rhapontin by biotransformation against propionibacterium acnes. | biotransformation is often used to improve chemical activity. we evaluated the antimicrobial activity of rhapontigenin, converted from rhapontin after treatment with pectinex. rhapontigenin showed 4-16 times higher antimicrobial activity than rhapontin. activity was higher against gram positive strains than gram negative strains. minimum inhibitory concentrations (mics) of rhapontigenin, retinol, and five antibiotics were determined by microbroth dilution method for antibiotic-sensitive and -res ... | 2010 | 20134237 |
| anterior chest wall abscess--an unusual complication of an odontogenic infection. | introduction: a majority of odontogenic infections can be successfully managed with routine incision and drainage and empirical antibiotics. sometimes an odontogenic infection may spread to contiguous spaces and descend along the neck causing significant morbidity and rarely even mortality. case report: we report a case of an odontogenic infection which had an unusual spread to the anterior chest wall. | 2010 | 20135335 |
| improving diagnostic criteria for propionibacterium acnes osteomyelitis: a retrospective analysis. | the identification of propionibacterium acnes in cultures of bone and joint samples is always difficult to interpret because of the ubiquity of this microorganism. the aim of this study was to propose a diagnostic strategy to distinguish infections from contaminations. this was a retrospective analysis of all patient charts of those patients with >or=1 deep samples culture-positive for p. acnes. every criterion was tested for sensitivity, specificity, and positive likelihood ratio, and then the ... | 2010 | 20141491 |
| in vitro antimicrobial activity of silver-processed catheters for neurosurgery. | to investigate the in vitro antibacterial activity of silver-processed catheters for use in neurosurgery using clinically predictive tests. | 2010 | 19942617 |
| tibial chronic osteomyelitis due to propionibacterium acnes in a patient with sickle cell anemia. | 2010 | 19913448 | |
| metabolism of conjugated linoleic acids and 18 : 1 fatty acids by ruminal bacteria: products and mechanisms. | cultures of ruminal bacteria known to metabolize unsaturated fatty acids were grown in medium containing 50 microg ml(-1) of geometric and positional isomers of conjugated linoleic acid (cla) or 18 : 1 fatty acids and 37.4 % deuterium oxide to investigate the mechanisms responsible for fatty acid metabolism. butyrivibrio fibrisolvens jw11 converted cis-9,trans-11-18 : 2 and trans-9,trans-11-18 : 2 to trans-11-18 : 1 as the main product, labelled at c-9, and metabolized trans-10,cis-12-18 : 2 to ... | 2010 | 19926650 |
| sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression. | various sebum free fatty acids (ffas) have shown antibacterial activity against a broad range of gram-positive bacteria, resulting in the suggestion that they are accountable, at least partially, for the direct antimicrobial activity of the skin surface. in this study, we examined the effects of sebum ffas on the antimicrobial peptide (amp)-mediated innate immune defense of human sebocytes. incubation of lauric acid, palmitic acid, or oleic acid (oa) with human sebocytes dramatically enhanced th ... | 2010 | 20032992 |
| identification of a secreted lipolytic esterase in propionibacterium freudenreichii, a ripening process bacterium involved in emmental cheese lipolysis. | lipolysis plays an important role in the formation of cheese flavor. in emmental cheese, the main part of lipolysis has been associated with the presence of propionibacterium freudenreichii, a species used as a ripening culture. our aim was to identify the most probable lipolytic esterase(s) involved in cheese lipolysis by p. freudenreichii. since cheese lipolysis mainly occurs during p. freudenreichii growth, we hypothesized that p. freudenreichii possesses secreted lipolytic esterase(s). for 1 ... | 2010 | 20038704 |
| progressive macular hypomelanosis is associated with a putative propionibacterium species. | 2010 | 20043017 | |
| in vitro activities of azole antifungal agents against propionibacterium acnes isolated from patients with acne vulgaris. | the gram-positive bacterium propionibacterium acnes is the causative agent of acne vulgaris. antibiotics such as tetracycline and macrolide derivatives are used to treat this skin disease; however, the isolation frequency of antibiotic-resistant p. acnes has been increasing. the anti-p. acnes activity of imidazole antifungal agents was reported more than 20 years ago, and since then, new azole antifungal agents have been marketed. thus, this study determined the in vitro activities of azole anti ... | 2010 | 20045949 |
| syntheses of carnosic acid and carnosol, anti-oxidants in rosemary, from pisiferic acid, the major constituent of sawara. | carnosic acid (2), a major anti-oxidant in rosemary (rosmarinus officinalis), was synthesized from pisiferic acid (1), the major constituent of sawara (chamaecyparis pisifera), via ortho-oxidation of the phenol using meta-chlorobenzoyl peroxide (mcbpo), chloroacetyl meta-chlorobenzoyl peroxide (camcbpo) or 2-iodoxybenzoic acid (ibx). carnosol (3), another anti-oxidant in rosemary, was synthesized from carnosic acid by oxidation with silver oxide. potent antibacterial activities against propionib ... | 2010 | 20045961 |
| the role of propionibacterium acnes in acne pathogenesis: facts and controversies. | we have come a long way since 1896, when it was first suggested that propionibacterium acnes, found in acne lesions, was the cause of acne. although several lines of evidence suggest the direct role of p acnes in acne, the mechanism by which p acnes contributes to the pathogenesis of acne is debated. the importance of p acnes in the induction and maintenance of the inflammatory phase of acne has been established. emerging data that inflammatory events occur in the very earliest stages of acne de ... | 2010 | 20082942 |
| the role of facial sebum secretion in acne pathogenesis: facts and controversies. | increased sebum secretion has been known as one of the major pathogenic factors in the development of acne; however, objective sebum measurement methods have been developed only recently. we have limited information about the association of sebum secretion, and the development of acne. there continues to be controversy about the role of sebum in the development of acne. this contribution will discuss sebum measurement techniques and the results of recent studies on the relationship of sebum, fac ... | 2010 | 20082943 |
| heart valve allograft decontamination with antibiotics: impact of the temperature of incubation on efficacy. | heart valve allografts are typically processed at 4°c in north america, including the step of antibiotic decontamination. in our own experience with heart valve banking, we often observe persistent positive cultures following decontamination at wet ice temperature. we hypothesized that warmer temperatures of incubation might increase the efficacy of the decontamination procedure. in a first series of experiments, 12 different bacterial species were grown overnight, frozen in standardized aliquot ... | 2010 | 20390362 |
| genome shuffling of propionibacterium shermanii for improving vitamin b12 production and comparative proteome analysis. | genome shuffling is an efficient approach for the rapid improvement of microbial phenotype. here we improved vitamin b12 production of propionibacterium shermanii by genome shuffling based on inactivated protoplast fusion. a genome shuffling strain with titer of vitamin b12 of 2.85 mgl(-1), named propionibacterium shermanii-f2-3, was obtained. the genome shuffled strain produced about 61% improvement of vitamin b12 over the parent strain after 96 h. comparative analysis of proteome profile was c ... | 2010 | 20553774 |
| carotid artery reconstruction for infected carotid patches. | infected carotid prosthetic patches (icpp) are a rare but catastrophic complication of carotid endarterectomy (cea). prevention and appropriate surgical management is essential. we report our experience of carotid artery reconstruction for icpp. | 2010 | 20705492 |
| propionibacterium acnes and staphylococcus epidermidis isolated from refractory endodontic lesions are opportunistic pathogens. | the predominant cultivable microbiota from 20 refractory endodontic lesions (9 with abscesses and 11 without abscesses) were determined, and propionibacterium acnes and staphylococcus epidermidis were among the most predominant organisms. the number of species identified from lesions with abscesses (14.1 ± 2.6) was significantly greater (p < 0.001) than the number from lesions without abscesses (7.4 ± 5.9). comparison of perioral isolates using repetitive extragenic palindromic pcr of the same s ... | 2010 | 20739494 |
| construction of metabolically biotinylated adenovirus with deleted fiber knob as targeting vector. | gene delivery vectors based on adenovirus, particularly human adenovirus serotype 5 (had5) have great potential for the treatment of variety of diseases. however, the tropism of had5 needs to be modified to achieve tissue- or cell- specific therapies for the successful application of this vector system to clinic. here, we modified had5 tropism by replacing the fiber knob which contains the coxsackievirus b and adenovirus receptor (car)-binding sites with a biotin acceptor peptide, a truncated fo ... | 2010 | 21073735 |
| laparoscopic ovarian tissue harvesting for cryopreservation: an effective and safe procedure for fertility preservation. | to critically review our experience with the method of laparoscopic ovarian tissue harvesting for ovarian cryopreservation. | 2010 | 20580151 |
| effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes. | probiotics can alleviate the symptoms of irritable bowel syndrome (ibs), possibly by stabilizing the intestinal microbiota. our aim was to determine whether ibs-associated bacterial alterations were reduced during multispecies probiotic intervention consisting of lactobacillus rhamnosus gg, l. rhamnosus lc705, propionibacterium freudenreichii ssp. shermanii js and bifidobacterium breve bb99. the intervention has previously been shown to successfully alleviate gastrointestinal symptoms of ibs. | 2010 | 20849659 |
| pelvic actinomycosis-like disease due to propionibacterium propionicum after hysteroscopic removal of an intrauterine device. | a female patient presented with episodes of fever and pain in the lower right abdomen after hysteroscopic removal of an intrauterine device 2 months earlier. pelvic actinomycosis originating from a tubo-ovarian abscess was diagnosed with propionibacterium propionicum, formerly known as arachnia propionica, as causative agent. | 2010 | 21068286 |
| safety of high doses of propionibacterium freudenreichii et-3 culture in healthy adult subjects. | propionibacterium freudenreichii et-3 (7025) culture, a cell-free product of whey fermentation by p. freudenreichii et-3, has been shown to promote the growth of bifidobacteria through the action of 1,4-dihydroxy-2-naphthoic acid (dhna). here we report the results of two clinical studies designed to evaluate the safety of high doses of p. freudenreichii et-3 culture medium. study 1 had a randomized, double-blind, crossover design. ten healthy male and four healthy female subjects received 45 tab ... | 2010 | 21172397 |
| treating acne in women. | 2010 | 21214119 | |
| in vivo antimicrobial effects of endodontic treatment procedures as assessed by molecular microbiologic techniques. | this culture-independent molecular microbiology study evaluated the antimicrobial effects of chemomechanical preparation supplemented by intracanal medication during treatment of teeth with apical periodontitis. | 2010 | 21329812 |
| glycerol enhances the antifungal activity of dairy propionibacteria. | dairy propionibacteria are widely used in starter cultures for swiss type cheese. these bacteria can ferment glucose, lactic acid, and glycerol into propionic acid, acetic acid, and carbon dioxide. this research examined the antifungal effect of dairy propionibacteria when glycerol was used as carbon source for bacterial growth. five type strains of propionibacteria were tested against the yeast rhodotorula mucilaginosa and the molds penicillium commune and penicillium roqueforti. the conversion ... | 2010 | 21331381 |
| effect of probiotic propionibacterium jensenii 702 supplementation on layer chicken performance. | the effects of the probiotic, propionibacterium jensenii 702 (pj 702), supplementation on egg productivity, egg shell thickness, fatty acid profile of eggs, and body weight in early layer hens were investigated. twenty eight twenty-week-old starter pullets were evenly divided into a treatment and a control group for an eight week experiment. each bird in the treatment group received 107 cfu pj 702 daily in a total volume of 1 ml by oral administration. no adverse effect was observed due to admin ... | 2010 | 21831750 |
| control of escherichia coli o157:h7 in corn silage with or without various inoculants: efficacy and mode of action. | this study aimed to evaluate the effectiveness of 3 commercial bacterial inoculants at controlling escherichia coli o157:h7 in corn silages during ensiling and feedout phases of silage production. a second objective was to determine whether the inoculants exhibited and transferred antibacterial activity against e. coli o157:h7 to the silages. chopped corn forage was ensiled after treatment with the following: distilled water (control); 5 x 10(5) cfu/g of e. coli o157:h7 (ec); ec and 1 x 10(6) cf ... | 2010 | 20172231 |
| bacterial colonization and infection of electrophysiological cardiac devices detected with sonication and swab culture. | electrophysiological cardiac devices are increasingly used. the frequency of subclinical infection is unknown. we investigated all explanted devices using sonication, a method for detection of microbial biofilms on foreign bodies. | 2010 | 20368521 |
| evaluation of the scanrdi(r) as a rapid alternative to the pharmacopoeial sterility test method: comparison of the limits of detection. | two sterility test methods, the scanrdi® rapid sterility test and the united states pharmacopeia/european pharmacopoeia/japanese pharmacopoeia (usp/ep/jp) compendial sterility test, were compared with respect to the limits of detection for the presence of viable microorganisms in aqueous solutions at low inoculation levels. the scanrdi® system employs a combination of direct fluorescent labeling techniques and solid-phase laser scanning cytometry to rapidly enumerate viable microorganisms from a ... | 2010 | 21502036 |
| propioniciclava tarda gen. nov., sp. nov., isolated from a methanogenic reactor treating waste from cattle farms. | facultatively anaerobic bacterial strains (wr061(t)and wr054) were isolated from rice-straw residue in a methanogenic reactor treating waste from cattle farms in japan. the two strains had almost the same phylogenetic and phenotypic properties. cells were gram-staining-positive, non-motile, non-spore-forming, irregular rods. the strains required cobalamin (vitamin b(12)). the strains utilized various carbohydrates including hexoses and disaccharides. the strains produced acetate and propionate f ... | 2010 | 20971831 |
| [postoperative discitis due to propionibacterium acnes]. | 2010 | 20493657 | |
| antibacterial activity of thai herbal extracts on acne involved microorganism. | ethyl acetate and methanol extracts of 18 thai medicinal plants were investigated for their antibacterial activity against propionibacterium acnes, stapylococcus aureus, and s. epidermidis. thirteen plant extracts were capable of inhibiting the growth of p. acnes and s. epidermidis, while 14 plant extracts exhibited an inhibitory effect on s. aureus. based on the broth dilution method, the ethyl acetate extract of alpinia galanga (l.) wild. (zingiberaceae) rhizome showed the strongest antibacter ... | 2010 | 20645714 |
| the etiologic role of infectious antigens in sarcoidosis pathogenesis. | sarcoidosis is a disease of unknown etiology, characterized pathologically by noncaseating granulomas that most commonly involve the lung, skin, lymph nodes, and eyes. syndromes with similar pathological and immunologic features to sarcoidosis such as chronic beryllium disease, hypersensitivity pneumonitis, and tuberculosis illustrate that granulomatous diseases may or may not have an infectious etiology. although the etiology of sarcoidosis remains unknown, recent molecular, genetic, and immuno ... | 2010 | 20665387 |
| delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. | upon delivery, the neonate is exposed for the first time to a wide array of microbes from a variety of sources, including maternal bacteria. although prior studies have suggested that delivery mode shapes the microbiota's establishment and, subsequently, its role in child health, most researchers have focused on specific bacterial taxa or on a single body habitat, the gut. thus, the initiation stage of human microbiome development remains obscure. the goal of the present study was to obtain a co ... | 2010 | 20566857 |
| randomized tolerability analysis of clindamycin phosphate 1.2%-tretinoin 0.025% gel used with benzoyl peroxide wash 4% for acne vulgaris. | the multiple etiologic factors involved in acne vulgaris make the use of several medications necessary to treat the condition. use of a fixed combination of clindamycin phosphate 1.2% and tretinoin 0.025% in conjunction with a benzoyl peroxide (bpo) wash 4% targets several pathologic factors simultaneously and mitigates the potential for clindamycin-induced propionibacterium acnes-resistant strains. new formulations may allow such regimens to be effectively used without overly reduced tolerabili ... | 2010 | 21284283 |
| an in vitro study on bacterial growth interactions and intestinal epithelial cell adhesion characteristics of probiotic combinations. | the aims of this study were to examine long-term growth interactions of five probiotic strains (lactobacillus casei 01, lactobacillus plantarum ha8, lactobacillus rhamnosus gg, lactobacillus reuteri atcc 55730 and bifidobacterium lactis bb12) either alone or in combination with propionibacterium jensenii 702 in a co-culture system and to determine their adhesion ability to human colon adenocarcinoma cell line caco-2. growth patterns of probiotic lactobacillus strains were not considerably affect ... | 2010 | 19949794 |
| [evaluating post-cataract surgery changes in bacterial culture tests with and without face-washing]. | to evaluate the changes in conjunctiva and eyelid culture test results before and after cataract surgery and their relation to face-washing. | 2010 | 20865920 |
| cutaneous malassezia microbiota in atopic dermatitis patients differ by gender and body part. | malassezia is a particularly important factor in the occurrence of atopic dermatitis (ad). | 2010 | 20924162 |
| normal human epidermal keratinocytes react differently than hacat keratinocyte cell line on exposure to propionibacterium acnes. | 2010 | 21352277 | |
| comparative study of the bactericidal effects of 5-aminolevulinic acid with blue and red light on propionibacterium acnes. | propionibacterium acnes naturally produces endogenous porphyrins that are composed of coproporphyrin iii (cpiii) and protoporphyrin ix (ppix). red light alone and photodynamic therapy (pdt) improve acne vulgaris clinically, but there remains a paucity of quantitative data that directly examine the bactericidal effects that result from pdt on p. acnes itself in vitro. the purpose of this study was to measure the difference of bactericidal effects of 5-aminolevulinic acid (ala)-pdt with red and bl ... | 2010 | 21352326 |
| antibiotic susceptibility of propionibacterium acnes isolated from acne vulgaris in korea. | propionibacterium acnes plays an important role in the development of acne, and inflammatory lesions are improved by antibiotics. long-term use of antibiotics may result in development of resistant strains and treatment failure. the aim of the present study was to investigate the isolation rate of p. acnes and to evaluate its antibiotic susceptibility to widely used antibiotics in acne in korea. among 46 patients, 31 p. acnes strains were cultured. isolated p. acnes was measured for minimum inhi ... | 2010 | 21352337 |
| case report of acremonium intraocular infection after cataract extraction. | a 64-year-old woman was referred to our clinic for the treatment of chronic uveitis in her left eye, which had started two weeks after an uncomplicated cataract extraction. she was treated with topical steroids with an initially good response, yet she subsequently developed severe inflammation and plaque-like material around the intraocular lens, despite continuous steroid therapy. she underwent pars plana vitrectomy, smear and culture of the aqueous and vitreous fluids, and intravitreal antibio ... | 2010 | 20379462 |
| propionibacterium acnes activates the igf-1/igf-1r system in the epidermis and induces keratinocyte proliferation. | propionibacterium acnes has a major role in the development of acne lesions. igf-1 stimulates the proliferation of keratinocytes via an activation of the igf-1 receptor (igf-1r). zinc has been proven to work efficiently against inflammatory acne and to modulate the igf-1 system. our objectives were to study the modulation of igf-1 and igf-1r expression by p. acnes extracts and to determine their modulation by zinc gluconate. in vivo, we analyzed biopsies of acne lesions and healthy skin, and in ... | 2010 | 20927124 |
| in vitro antimicrobial susceptibility of propionibacterium acnes isolated from acne patients in northern mexico. | antimicrobials are essential in acne therapy. in the last decades, propionibacterium acnes has become resistant to different antibiotics. | 2010 | 20931669 |
| prevalence of propionibacterium acnes in diseased prostates and its inflammatory and transforming activity on prostate epithelial cells. | prostate cancer (pca) is the second leading cause of male cancer deaths in the western world. mounting evidence has revealed that chronic inflammation can be an important initiating factor of pca. recent work has detected the anaerobic gram-positive bacterium propionibacterium acnes in cancerous prostates, but with wide-ranging detection rates. here, using in situ immunofluorescence (isif), p. acnes was found in 58 out of 71 (81.7%) tested cancerous prostate tissue samples, but was absent from h ... | 2010 | 20943438 |
| fermentation metabolites from lactobacillus gasseri and propionibacterium freudenreichii exert bacteriocidal effects in mice. | lactobacillus gasseri oll 2716 promotes the elimination of helicobacter pylori and is utilized in yogurts that are specifically labeled as health foods. on the other hand, milk whey fermented by propionibacterium freudenreichii et-3, which increases the numbers of bifidobacterium, is effective for intestinal disorders. we previously demonstrated that oral administration of l. gasseri and p. freudenreichii fermentation metabolites (lp-fm) improved calf intestinal microflora and reduced the incide ... | 2010 | 20954806 |
| time course and specificity of lipolysis in swiss cheese. | controlling lipolysis in cheese is necessary to ensure the formation of desirable flavor. to get a better understanding of the mechanism of lipolysis in swiss cheese, cheeses were manufactured with and without (control) the addition of propionibacterium freudenreichii. products of lipolysis were quantified throughout ripening. half of the free fatty acids (ffa) released in milk (3.66 mg/g fat), in particular the short-chain ffa, were lost in the whey during curd drainage, whereas diglycerides an ... | 2010 | 20961108 |
| production of folate by bacteria isolated from oat bran. | twenty bacteria isolated from three commercial oat bran products were tested for their folate production capability. the bacteria as well as some reference organisms were grown until early stationary phase on a rich medium (ypd), and the amount of total folate in the separated cell mass and the culture medium (supernatant) was determined by microbiological assay. folate vitamer distribution was determined for eight bacteria including one isolated from rye flakes. for seven bacteria the effect of ... | 2010 | 20708290 |
| activity of an antimicrobial hydrocephalus shunt catheter against propionibacterium acnes. | shunt infection is a major complication affecting approximately 10% of procedures. propionibacterium acnes, an anaerobic skin bacterium, is increasingly recognized as a shunt pathogen, causing up to 14% of infections. though susceptible to penicillin and cephalosporins, p. acnes shunt infections are not preventable by means of perioperative prophylaxis, due to poor cerebrospinal fluid penetration. antimicrobial shunts with activity against staphylococci are available, but their activity against ... | 2010 | 20837763 |
| identification of bacteria enduring endodontic treatment procedures by a combined reverse transcriptase-polymerase chain reaction and reverse-capture checkerboard approach. | this study identified the bacterial taxa enduring endodontic treatment procedures by using a combined 16s ribosomal rna-based reverse-transcriptase polymerase chain reaction (rt-pcr) and reverse-capture checkerboard hybridization approach. | 2010 | 20003934 |
| bilateral clavicle fracture external fixation. | fractures of the middle third of the clavicle are frequent and their conservative treatment ends in bone union in nearly 95% of cases. surgical treatment is unanimously indicated with open fractures or in cases of cutaneous damage, neurovascular complications, and impaction of the shoulder stump syndromes. we report herein a case of bilateral fractures of the clavicle that required double stabilization with an external fixator following major cutaneous damage appearing after the initial conserva ... | 2010 | 20850405 |
| mutagenesis of propionibacterium acnes and analysis of two camp factor knock-out mutants. | p. acnes is a skin commensal that is frequently associated with inflammatory diseases such as acne vulgaris. despite the availability of the genome sequence functional studies on p. acnes are scarce due to a lack of methods for genetic manipulation of this bacterium. here we present an insertional mutagenesis approach for the inactivation of specific p. acnes genes. the gene of interest can be disrupted and replaced with an erythromycin-resistance cassette by employing homologous recombination. ... | 2010 | 20850482 |
| apical root canal microbiota as determined by reverse-capture checkerboard analysis of cryogenically ground root samples from teeth with apical periodontitis. | bacteria located in the apical root canal system potentially participate in the pathogenesis of apical periodontitis. detection and identification of apical bacteria can be compromised because of limitations in conventional sampling and identification procedures. this study identified several bacterial taxa in the apical and middle/coronal segments of primarily infected root canal system by using pulverized root segments and a culture-independent molecular method. | 2010 | 20850664 |
| isolation of a novel bacteriophage specific for the periodontal pathogen fusobacterium nucleatum. | fusobacterium nucleatum is a periodontal pathogen that has been directly associated with the development and progression of periodontal disease, a widespread pathology that affects the support tissues of the tooth. we isolated a new bacteriophage (fnpφ02) that specifically infects this bacterium. transmission electron microscopy showed that the virion is composed of an icosahedral head and a segmented tail. the size of the phage genome was estimated to be approximately 59 kbp of double-stranded ... | 2010 | 20851973 |
| production of cis-9,trans-11-conjugated linoleic acid in camelina meal and okara by an oat-assisted microbial process. | a method to obtain cis-9,trans-11-conjugated linoleic acid (c9,t11-cla) into camelina meal and okara, the byproducts of plant oil processing, is described. the triacylglycerols in these materials were hydrolyzed with the aid of lipolytically active oat flour for 3 weeks at a water activity of 0.70. the resulting free linoleic acid was then isomerized predominantly to c9,t11-cla by resting cells of propionibacterium freudenreichii ssp. shermanii in 5% aqueous camelina meal and okara slurries. in ... | 2010 | 20088592 |
| development of a nondestructive fluorescence-based enzymatic staining of microcolonies for enumerating bacterial contamination in filterable products. | develop a nondestructive fluorescence-based staining procedure to rapidly detect and enumerate bacteria in filterable samples. | 2010 | 20880209 |
| photodynamic therapy in the management of acne: an update. | acne, one of the most common dermatological diseases, is characterized by inflammatory and noninflammatory lesions that may progress to scars. starting from pubertal age groups, it can affect adults in the age group 35-40 or more. the conventional therapies for treatment of acne are facing roadblocks because of the antibiotic resistance developing against propionibacterium acnes. this has led to trying new therapies, of which photodynamic therapy (pdt) seems to be the one under intensive study. ... | 2010 | 20883294 |
| the complete genome of propionibacterium freudenreichii cirm-bia1, a hardy actinobacterium with food and probiotic applications. | propionibacterium freudenreichii is essential as a ripening culture in swiss-type cheeses and is also considered for its probiotic use. this species exhibits slow growth, low nutritional requirements, and hardiness in many habitats. it belongs to the taxonomic group of dairy propionibacteria, in contrast to the cutaneous species p. acnes. the genome of the type strain, p. freudenreichii subsp. shermanii cirm-bia1 (cip 103027(t)), was sequenced with an 11-fold coverage. | 2010 | 20668525 |
| antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual week. | little is known about the antecedents of microcephaly in early childhood among children born at extremely low gestational age. | 2010 | 20674197 |
| acne and diet: truth or myth? | numerous studies were published over the last 50 years to investigate whether diet is associated with the etiology of acne. although older studies well known by dermatologists that refute the association between acne and diet exist, their scientific foundation is weak. new articles have recently brought to light evidence contrary to previous findings. therefore, we would like to investigate whether diet, directly or indirectly, influences one or more of the four fundamental etiopathogenic pillar ... | 2010 | 20676468 |
| [microbial contamination of nipradiol with and without benzalkonium chloride]. | to compare microbial contamination of nipradiol both with and without benzalkonium chloride (bac). | 2010 | 20681256 |
| innate, antigen-independent role for t cells in the activation of the immune system by propionibacterium acnes. | propionibacterium acnes is a human commensal but also an opportunistic pathogen. in mice, p. acnes exerts strong immunomodulatory activities, including formation of intrahepatic granulomas and induction of lps hypersensitivity. these activities are dependent on p. acnes recognition via tlr9 and subsequent il-12-mediated ifn-gamma production. we show that p. acnes elicits il-12p40 and p35 mrna expression in macrophages, and ifn-gamma mrna in liver cd4(+) t cells and nk cells. after priming with p ... | 2010 | 20690177 |
| does inflammatory acne result from imbalance in the keratinocyte innate immune response? | acne is a multifactorial chronic disease affecting around 80% of teenage population. the pathogenesis of acne involves inflammatory reactions and colonization by the propionibacterium acnes (p. acnes) strain. p. acnes stimulates the keratinocytes involved in the innate immune response, the intensity of which could be influenced either by bacterial intrinsic factors or by endogenous factors of the host. | 2010 | 20691803 |
| protease-activated receptor-2 mediates the expression of inflammatory cytokines, antimicrobial peptides, and matrix metalloproteinases in keratinocytes in response to propionibacterium acnes. | propionibacterium acnes (p. acnes) has been known to produce various exogenous proteases, however, their role in acne pathogenesis remains largely unknown. proteases elicit cellular responses, at least in part, via proteinase-activated receptor-2 (par-2), which is known to mediate inflammation and immune response. in this study, we investigated whether proteases from p. acnes could activate par-2 on keratinocytes and induce pro-inflammatory cytokines, antimicrobial peptides (amps), and matrix me ... | 2010 | 20697725 |
| quantitation of major human cutaneous bacterial and fungal populations. | because the human skin microbiota may play roles in the causation or modification of skin diseases, we sought to provide initial quantitative analysis from different cutaneous locations. we developed quantitative pcrs to enumerate the total bacterial and fungal populations, as well as the most common bacterial and fungal genera present in six locales, in eight healthy subjects. we used a set of primers and taqman mgb probes based on the bacterial 16s rrna and fungal internally transcribed spacer ... | 2010 | 20702672 |
| proteomic identification of secreted proteins of propionibacterium acnes. | the anaerobic gram-positive bacterium propionibacterium acnes is a human skin commensal that resides preferentially within sebaceous follicles; however, it also exhibits many traits of an opportunistic pathogen, playing roles in a variety of inflammatory diseases such as acne vulgaris. to date, the underlying disease-causing mechanisms remain ill-defined and knowledge of p. acnes virulence factors remains scarce. here, we identified proteins secreted during anaerobic cultivation of a range of sk ... | 2010 | 20799957 |
| taurine bromamine (taubr)--its role in immunity and new perspectives for clinical use. | this review is an attempt to summarize our knowledge about taurine bromamine (taubr) properties, its role in innate immunity and its therapeutic potential.taubr and taurine chloramine (taucl) are major haloamines generated by eosinophils and neutrophils at a site of inflammation. both haloamines share anti-inflammatory and anti-oxidant properties. taubr, similarly to taucl, decreases the production of proinflammatory mediators. their anti-inflammatory and anti-oxidant activities are enhanced by ... | 2010 | 20804605 |
| population genetic analysis of propionibacterium acnes identifies a subpopulation and epidemic clones associated with acne. | the involvement of propionibacterium acnes in the pathogenesis of acne is controversial, mainly owing to its dominance as an inhabitant of healthy skin. this study tested the hypothesis that specific evolutionary lineages of the species are associated with acne while others are compatible with health. phylogenetic reconstruction based on nine housekeeping genes was performed on 210 isolates of p. acnes from well-characterized patients with acne, various opportunistic infections, and from healthy ... | 2010 | 20808860 |
| effects of two commercially available immunostimulants on leukocyte function of foals following ex vivo exposure to rhodococcus equi. | the objective of this study was to determine the effect of immunostimulants on neutrophil, macrophage, and lymphocyte function following ex vivo exposure to rhodococcus equi. eighteen foals were randomly assigned to one of 3 treatment groups. treatment consisted of inactivated propionibacterium acnes (pa), inactivated parapoxvirus ovis (ppvo), or saline (control) administered on days 0 (7 days of age), 2, and 8. bronchoalveolar lavage (bal) fluid and blood were collected on days 0 (baseline), 12 ... | 2010 | 20822815 |
| bacterial 16s sequence analysis of severe caries in young permanent teeth. | previous studies have confirmed the association of the acid producers streptococcus mutans and lactobacillus spp. with childhood caries, but they also suggested these microorganisms are not sufficient to explain all cases of caries. in addition, health-associated bacterial community profiles are not well understood, including the importance of base production and acid catabolism in ph homeostasis. the bacterial community composition in health and in severe caries of the young permanent dentition ... | 2010 | 20826648 |
| persistence of probiotic strains in the gastrointestinal tract when administered as capsules, yoghurt, or cheese. | most clinical studies of probiotics use freeze-dried, powdered bacteria or bacteria packed in capsules. however, probiotics are commercially available in various food matrices, which may affect their persistence in the gastrointestinal tract. the objective of the study was to compare oral and faecal recovery during and after administration of a combination of lactobacillus rhamnosus gg and lc705, propionibacterium freudenreichii subsp. shermanii js, and bifidobacterium animalis subsp. lactis bb1 ... | 2010 | 21074284 |
| benzoyl peroxide: enhancing antibiotic efficacy in acne management. | benzoyl peroxide is one of the most widely used topical agents for acne. it has potent antibacterial and mild anti-inflammatory and comedolytic effects. to treat mild to moderate acne, it can be used alone or in combination with topical antibiotics and topical retinoids. the combination of benzoyl peroxide with either erythromycin or clindamycin is synergistic and well-tolerated. in more severe acne, when oral antibiotics are required, benzoyl peroxide can contribute to suppressing the emergence ... | 2010 | 21076800 |
| potent antimicrobial action of triclosan-lysozyme complex against skin pathogens mediated through drug-targeted delivery mechanism. | triclosan (tcs), an antimicrobial agent that inhibits bacterial fatty acid synthesis by blocking the active site of enoyl-acp reductase (fabi), is a water-insoluble agent that limits its therapeutic candidacy. we have recently shown that the water solubility and antimicrobial activity of tcs were greatly enhanced when complexed to lysozyme (lz). this study is to examine the therapeutic potential of triclosan-lysozyme (t-lz) complex against common skin pathogens expressing different levels of fab ... | 2010 | 21078387 |
| the bifidogenic growth stimulator inhibits the growth and respiration of helicobacter pylori. | triple therapy with amoxicillin, clarithromycin, and a proton-pump inhibitor is a common therapeutic strategy for the eradication of helicobacter pylori (h. pylori). however, frequent appearance of clarithromycin-resistant strains is a therapeutic challenge. while various quinones are known to specifically inhibit the growth of h. pylori, the quinone 1,4-dihydroxy-2-naphthoic acid (dhna) produced by propionibacterium has strong stimulating effect on bifidobacterium. we were interested to see whe ... | 2010 | 21083748 |
| staphylococcus aureus hijacks a skin commensal to intensify its virulence: immunization targeting β-hemolysin and camp factor. | the need for a new anti-staphylococcus aureus therapy that can effectively cripple bacterial infection, neutralize secretory virulence factors, and lower the risk of creating bacterial resistance is undisputed. here, we propose what is, to our knowledge, a previously unreported infectious mechanism by which s. aureus may commandeer propionibacterium acnes, a key member of the human skin microbiome, to spread its invasion and highlight two secretory virulence factors (s. aureus β-hemolysin and p. ... | 2010 | 21085191 |
| [how i explore...skin by photodiagnosis using skin fluorescence and its functional imaging]. | under specific light illumination, skin produces peculiar fluorescent aspects. such property can be used to provide diagnostic arguments or to disclose some peculiar functions of the skin. some superficial infections (erythrasma, tinea versicolor, dermatophytic tinea,..) reveal fluorescence that may be intense. the pilosebaceous follicles enriched in propionibacterium spp show fluorescence. such property is lost during some anti-acne treatments. a quenching effect is observed after application o ... | 2010 | 21086585 |
| fluorescence diagnostic imaging in patients with acne. | orange-red fluorescence in the follicle openings, induced by ultraviolet a light, originates from porphyrins, the metabolic products of propionibacteria acnes. | 2010 | 21091785 |
| [pathophysiological advances in acne]. | acne is a chronic disorder caused by multiple factors. recent advances suggest that inflammation plays an initial role and propionibacterium acnes plays a major role by initiating, maintaining and extending acne. | 2010 | 21095495 |
| a review of the safety and efficacy of benzoyl peroxide (5.3%) emollient foam in the management of truncal acne vulgaris. | this article reviews findings of studies regarding the treatment of truncal acne with benzoyl peroxide formulations and, in particular, studies utilizing a 5.3% benzoyl peroxide foam. its formulation of micronized benzoyl peroxide particles in an emollient foam vehicle offers significant clinical and bioavailability advantages that enhance follicular penetration and skin moisturization. a key consideration for topical management of truncal acne is whether the treatment application method allows ... | 2010 | 21103313 |
| tlr2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. | a diverse environment challenges skin to maintain temperature, hydration, and electrolyte balance while also maintaining normal immunological function. rosacea is a common skin disease that manifests unique inflammatory responses to normal environmental stimuli. we hypothesized that abnormal function of innate immune pattern recognition could explain the enhanced sensitivity of patients with rosacea, and observed that the epidermis of patients with rosacea expressed higher amounts of toll-like r ... | 2010 | 21107351 |
| promising immunomodulatory effects of selected strains of dairy propionibacteria as evidenced in vitro and in vivo. | immunomodulatory properties of 10 dairy propionibacteria, analyzed on human peripheral blood mononuclear cells (pbmcs), revealed a highly strain-dependent induction of anti-inflammatory cytokine interleukin 10 (il-10). two selected strains of propionibacterium freudenreichii showed a protective effect against two models of colitis in mice, suggesting a probiotic potential predicted by immune-based selection criteria for these cheese starter bacteria. | 2010 | 20971874 |
| bacterial contamination of needles used for intravitreal injections: a prospective, multicenter study. | to determine the incidence of bacterial contamination of needles used for intravitreal injections. | 2010 | 21034310 |
| mis416, a non-toxic microparticle adjuvant derived from propionibacterium acnes comprising immunostimulatory muramyl dipeptide and bacterial dna promotes cross-priming and th1 immunity. | propionibacterium acnes was modified using biochemical extraction methods generating a suspension of microparticles (mis416) comprising a minimal cell wall skeleton rich in immunostimulatory crosslinked muramyl dipeptide repeats and native bacterial dna fragments, each which have known adjuvant activity. in vitro studies demonstrated that mis416 was readily internalized by human myeloid and plasmacytoid dc inducing cytokine secretion and cell activation/maturation. vaccination studies in mice us ... | 2010 | 21034827 |
| the unconventional antimicrobial peptides of the classical propionibacteria. | the classical propionibacteria produce genetically unique antimicrobial peptides, whose biological activities are without equivalents, and to which there are no homologous sequences in public databases. in this review, we summarize the genetics, biochemistry, biosynthesis, and biological activities of three extensively studied antimicrobial peptides from propionibacteria. the propionicin t1 peptide constitutes a bona fide example of an unmodified general secretory pathway (sec)-dependent bacteri ... | 2010 | 21038096 |
| detection of microbial contaminants in mammalian cell cultures using a new fluorescence-based staining method. | microbial contamination of cell culture production processes is a current concern for biopharmaceutical industries. traditional testing methods require several days to detect contamination and may advantageously be replaced by a rapid detection method. we developed a new method combining membrane filtration to microcolonies fluorescence staining method (mfsm) and compared it to epifluorescence microscopy. | 2010 | 21039669 |
| efficacy and safety of combined ethinyl estradiol/drospirenone oral contraceptives in the treatment of acne. | acne is a common disorder affecting the majority of adolescents and often extends into adulthood. the central pathophysiological feature of acne is increased androgenic stimulation and/or end-organ sensitivity of pilosebaceous units leading to sebum hypersecretion and infundibular hyperkeratinization. these events lead to propionibacterium acnes proliferation and subsequent inflammation. hormonal therapy, including combined oral contraceptives (ocs), can attenuate the proximate androgenic trigge ... | 2010 | 21072290 |
| sinogenic orbital and subperiosteal abscesses: microbiology and methicillin-resistant staphylococcus aureus incidence. | to assess the current bacteriology and the incidence of methicillin-resistant staphylococcus aureus in orbital and subperiosteal abscesses of paranasal sinus disease origin. | 2010 | 20723777 |
| efficacy of oral antibiotics on acne vulgaris and their effects on quality of life: a multicenter randomized controlled trial using minocycline, roxithromycin and faropenem. | there are few clinical studies which compare the efficacy and patient satisfaction for oral antibiotics to treat inflammatory acne. to clarify the difference between oral antibiotics, acne patients with moderate to severe inflammatory eruptions were randomized into three groups, and each patient was given minocycline (mino), roxithromycin (rxm) or faropenem (frpm) for 4 weeks, followed by 4 weeks of observation without any oral antibiotics. we estimated the reduction rate of inflammatory lesion ... | 2010 | 21269305 |
| bacteriologic culture of excised intervertebral disc from immunocompetent patients undergoing single level primary lumbar microdiscectomy. | study design: a consecutive case series from a single center of patients undergoing primary microdiscectomy for lumbar herniated nucleus pulposus (hnp) who received microbiologic laboratory culture of excised disc material. objective: to determine the prevalence of positive bacterial cultures in the disc material of immunocompetent patients without diabetes mellitus or other immune compromise. summary of background data: the intradiscal space is a physiologically tenuous environment in terms of ... | 2010 | 21150662 |
| quinone-dependent d-lactate dehydrogenase dld (cg1027) is essential for growth of corynebacterium glutamicum on d-lactate. | corynebacterium glutamicum is able to grow with lactate as sole or combined carbon and energy source. quinone-dependent l-lactate dehydrogenase lldd is known to be essential for utilization of l-lactate by c. glutamicum. d-lactate also serves as sole carbon source for c. glutamicum atcc 13032. | 2010 | 21159175 |
| interleukin-10 secretion from cd14+ peripheral blood mononuclear cells is downregulated in patients with acne vulgaris. | acne is a common chronic inflammatory dermatosis of the pilosebaceous unit. it is characterized by seborrhoea, comedone formation and an inflammatory response consistent with defective cellular immunity to propionibacterium acnes. | 2010 | 19796181 |
| multilocus sequence typing of propionibacterium freudenreichii. | propionibacterium freudenreichii is used as a ripening culture in swiss cheese manufacture. this study investigates the molecular diversity and the population structure of this bacterium via multilocus sequence typing (mlst). internal fragments of seven genes sequenced for 113 strains of different subspecies and origins allowed the resolution of 46 sequence types (sts) with occurrence frequencies ranging from 1 to 11. the core genome of the species harbours a low level of nucleotide polymorphism ... | 2010 | 21176990 |
| recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice. | we have previously demonstrated that oral administration of a metabolically active bifidobacterium breve strain, with ability to form cis-9, trans-11 conjugated linoleic acid (cla), resulted in modulation of the fatty acid composition of the host, including significantly elevated concentrations of c9, t11 cla and omega-3 (n-3) fatty acids in liver and adipose tissue. in this study, we investigated whether a recombinant lactobacillus expressing linoleic acid isomerase (responsible for production ... | 2010 | 21178166 |
| synthesis and antimicrobial activity of long-chain 3,4-epoxy-2-alkanones. | 3,4-epoxy-2-dodecanone, a major component in the preorbital gland of the african grey duiker (sylvicapra grimmia), showed antimicrobial activity in preliminary tests. the c(11) to c(17) homologues of this compound were prepared and their activity against several pathogenic dermal bacteria and fungi was tested. 3,4-epoxy-2-dodecanone and 3,4-epoxy-2-tridecanone inhibited the growth of trichophyton mentagrophytes at 25 îg/ml. moderate inhibition of the growth of the bacteria propionibacterium acne ... | 2010 | 21179314 |
| production of 5-aminolevulinic acid by propionibacterium acidipropionici tistr442. | propionibacterium acidipropionici tistr442 produced the highest amount of 5-aminolevulinic acid (ala) when cultivated in medium supplemented with glycine at 18g/l. ala production correlated with ala synthase activity, whereas ala dehydratase activity was maintained at a low level. ala yield reached 405mg/l after prolonged cultivation for 1 month. | 2010 | 21185777 |
| suppressive effects of 1,4-dihydroxy-2-naphthoic acid administration on bone resorption. | the main component of the metabolic by-products of fermentation by propionibacterium freudenreichii et-3 is 1,4-dihydroxy-2-naphthoic acid (dhna), which has a naphthoquinone skeleton, as in vitamin k2. this study showed that dhna improved bone mass reduction with osteoporosis model mice caused by fk506. | 2010 | 19813044 |
| efficacy of an anaerobic swab transport system to maintain aerobic and anaerobic microorganism viability after storage at -80 degrees c. | an amies agar gel swab transport system was evaluated for its ability to maintain bacterial viability and relative quantity after freezing at -80°c. nine american type culture collection (atcc) bacterial strains were used: 3 anaerobic strains (propionibacterium acnes, peptostreptococcus anaerobius, and clostridium sporogenes) and 6 facultative or strict aerobic bacterial strains (stenotrophomonas maltophilia, escherichia coli ([atcc 25922 and atcc 11775], salmonella enterica subsp. enterica sero ... | 2011 | 21217035 |