Publications

gentian violet as a possible fungal inhibitor in poultry feed: plate assays on its antifungal activity.		1974	4213944
fatty liver and kidney syndrome in chicks. effects on liver and kidney of diets causing the syndrome.		1974	4214519
the survival of microfungi in the nests of tree-sparrow (passer montanus l.) in the nest-boxes over the winter season.		1974	4216854
metabolic products of microorganisms. 132. uptake of iron by neurospora crassa. 3. iron transport studies with ferrichrome-type compounds.		1974	4275989
late asthmatic reactions to inhalation of fractions from extracts of candida albicans and asperguillus fumigatus.	to investigate the mechanism of late respiratory reactions after exposure to extracts of c.albicans and a.fumigatus, patients with asthma were studied with skin tests, inhalation tests and serologic tests including precipitin tests, using purified polysaccharide fraction (ps) and protein fraction (p). thirty five inhalation tests in 30 patients separated reactors with late onset into two groups, 7 patients with precipitins, intermediate dermal and respiratory reactions, and 10 patients with dela ...	1974	4283487
selenium effect on the growth of carcinogenic fungi and cytotoxic action of aflatoxin b1 on lymphocyte culture and on embryonal development of xenopus laevis.	the authors report the results of investigations on the protective effect of selenium against teratogenic and cytotoxic action of aflatoxin b1 and the inhibitory action of this element on the growth of fungi producing carcinogenic aflatoxins. sodium selenate inhibited the growth of cultures of such fungi belonging to the class fungi imperfecti as aspergillus flavus, aspergillus fumigatus, penicillium meleagrinum and penicillium rougolosum. added to cell cultures of lymphocytes sodium selenate in ...	1975	817275
[mycological control of laboratory animals].		1975	821323
[effect of the standard of hygiene in the care for breeding boars and of the technic of semen collection on the number of pathogens in the boar ejaculate].	the microbiological examination of 48 ejaculates obtained by an artificial vagina revealed an average number of 178 000 germs per 1 ml of semen (1900 - 758 000). when the technique was changed, the manual method being employed, 23 ejaculates were obtained from the same boars and the microbiological examination revealed 44 200 germs per 1 ml of semen, on an average. in the second part of the trial 85 ejaculates obtained by an artificial vagina from 17 breeding boars were subject to microbiologica ...	1975	814677
primary interaction between antibody and components of alternaria. i. immunology and chemical characteristics of labeled antigens.	components were isolated from alternaria tenuis and its culture filtrate, and were radiolabeled with 123-i. the labeled antigenic components had a high polysaccharide content as determined by staining patterns following electrophoresis in polyacrylamide gels and by inactivation with sodium metaperiodate. a primary binding test was employed to detect and measure serum antibodies to the components from a. tennuis. this procedure was more sensitive in detecting antibodies that bound to antigens tha ...	1975	48526
glycoprotein enzymes secreted by aspergillus fumigatus: purification and properties of a second beta-glucosidase.	a second extracellular beta-glucosidase (betalarge) of aspergillus fumigatus was purified to homogeneity and shown to be a glycoprotein, as determined by polyacrylamide gel electrophoresis followed by staining for protein and for carbohydrate. its molecular weight was approximately 340,000 by gel filtration, while sodium dodecyl sulfate-polyacrylamide gel electrophoresis gave an apparent molecular weight of 170,000, suggesting that the enzyme has two subunits. the glucosidase contained covalentl ...	1975	51848
high-temperature production of protein-enriched feed from cassava by fungi.	a simple, nonaseptic, low-cast process for the conversion of cassava, a starchy tropical root crop, into microbial protein for use as animal feed was sought. screening tests culminated in the isolation of a thermotolerant, amylase-producing mold, designated i-21, which was identified as aspergillus fumigatus. the optimum ph for protein synthesis was 3-5, but the optimum temperature was less than the desired temperature (larger than or equal to 45 c) required for a nonaseptic fermentation. a. fum ...	1975	2105
kinetics of mucous cells in bronchial and bronchiolar epithelia during aerogenic elicitation with aspergillary proteins. a quantitative cytologic study.	during a prolonged exposure of rabbits to aerosols with asperigillary antigens, the content of bronchial and bronchiolar epithelia in mucus-secreting cells was quantified. in normals, the mucous cells do not exceed 3.2 per cent in bronchial epithelium and 0.44 per cent in bronchiolar one. after exposure, these proportions rapidly increase, after a primary discharge of goblet cells. the mucous cells become a majority after 7 exposures in bronchi and after 21 in bronchiolar epithelium. the maturat ...	1975	129684
pathogens, their sources and control--part two.		1975	162781
bronchial provocation tests in etiologic diagnosis and analysis of asthma.		1975	173214
[action of migillin on its own producer, asp. fumigatus].	addition of migillin to the nutrient medium at early stages of the fungus development induced at one hand inhibition of the fungus growth during the first 24-48 hours and stimulation of the biomass accumulation during the following hours of the development and on the other hand it induced inactivation of migillin added and inhibition of production of the "own" antibiotic. the migillin effect was accompanied by a delay in liberation of the substance with adsorption at 260nm from the mycelium.	1975	237468
[randomised investigations of some tyrolean swimming pools for the presence of trichomonas vaginalis and pathogenic fungi (author's transl)].	trichomonads were not demonstrated either microscopically or by culture in water samples from 15 public open air swimming pools in the tyrol. on the other hand, a small number of pathogenic fungi (candida albicans, trichophyton mentagrophytes, tr. verrucosum) were cultured from pool water with a free chlorine content of less than 0.35 mg/l (dpd 1). dermatophytes could also be demonstrated by cultures of the coatings on the surfaces of tiles in the showers, and of pool surrounding-and cabin tract ...	1975	239503
proceedings: purification and characteristics of hemolytic toxin from aspergillus fumigatus.		1975	778450
[isolation of phthioic acid of aspergillus fumigatus and its biological activities].		1975	765548
[isolation and purification of hemolytic toxin of aspergillus fumigatus].		1975	765557
[fungi in bronchial secretion of children with nonspecific bronchopulmonary diseases].		1975	765599
[comparative characteristic of antibiotic activity of different aspergillus fumigatus strains].		1975	765689
variation in vivo and isolation of aspergillus fumigatus from a case of human aspergillosis.		1975	765815
[metabolic products of microorganisms. 150. ferricrocin, triacetylfusigen and other sideramines from fungi of the genus aspergillus, group fumigatus (author's transl)].	the sideramines of 14 species of the genus aspergillus, group fumigatus, were isolated and analyzed. ferricrocin was identified in 11 extracts, ferrichrome in 2 others. a lipophilic sideramine produced by 4 species was identified as triacetylfusigen, another minor component as triacetylfusigen b. six species produced an alanine-containing sideramine, which may be identical with ferrichrom c.	1975	766717
sudden infant death syndrome in south australia. measurement of serum ige antibodies to three common allergens.	radioallergosorbent test (rast) studies showed that ige antibodies to dermatophagoides pteronyssinus (house dust mite), aspergillus fumigatus and bovine beta-lactoglobulin were significantly elevated in the sera of infants who died as a result of the sudden death in infancy syndrome (sdis). no significant differences were found in the levels of total ige, iga, igg or igm in the sera of sdis victims or controls. the possible role of hypersensitivity in the aetiology of sdis is discussed.	1975	768723
skin reaction and macrophage migration inhibition tests for polysaccharides from aspergillus fumigatus and candida albicans.	guinea pigs sensitized with purified galactomannan from aspergillus fumigatus and mannan from candida albicans, each containing negligible quantities of nitrogen, were examined for their immunological responses against the corresponding polysaccharides with respect to the delayed-type skin reaction and the macrophage migration inhibition phenomenon. in both cases, the delayed-type skin reaction test and the macrophage migration inhibition test showed positive results. the reactivity was stronger ...	1975	772255
experimental aspergillosis and phycomycosis in mice.		1975	773815
cystic fibrosis--immunological reactions to a. fumigatus and common allergens.	immunological studies of forty-three patients with cystic fibrosis showed that positive prick tests to at least one common allergen were obtained in 70%, to multiple allergens in 28% and to a. fumigatus in 50%. specific ige antibodies against these allergens were found in the appropriate subjects. in spite of this evidence of type 1, ige, sensitization none of the patients had a history of infantile eczema. intracutaneous tests with a. fumigatus extract gave types 1 and 3 reactions in sixteen pa ...	1975	802880
animal model of fusarium solani keratitis.	because of the frequency of fungal keratitis due to fusarium solani, we needed a sustained, progressive infection in an animal model to determine the mechanisms of pathogenicity and to evaluate the new antifungal agents. pigmented rabbits interlamellarly injected with actively germinating conidia from lyophilized temperature-tolerant strains of f. solani produced sustained culture-positive ulcers in high percentage of eyes at two and three weeks, pretreatment with subconjunctival corticosteroids ...	1975	804817
hydrogen peroxide sterilization of hydrophilic contact lenses.	a new, simple, and effective procedure for the sterilization of soft contact lenses utilizes hydrogen peroxide, an inexpensive and readily availiable solution.	1975	805580
phyllosphere microflora of some egyptian plants.	the fungal and bacterial flora of the leaf surfaces of five plants growing in egypt were studied. the fungal flora showed seasonal fluctuations with at least one peak. twenty three genera with fifty three species were found, aspergillus and penicillium being most common. other fungi showed variable percentages of the total count. nitrogen-fixing bacteria were not isolated from the phyllosphere of the five plant species. micrococci were most predominant among the epiphytic bacteria. spore-forming ...	1975	806505
antibody formation in rabbits exposed to aerosols containing spores of aspergillus fumigatus.	rabbits were exposed once a day for 1 to 10 consecutive days to aerosols containing spores of aspergillus fumigatus. the number of spores used at each 5-minute exposure during an experiment was constant, but the level of exposure was different for each of the 4 experiments. precipitating antibodies were detected only in serums from rabbits that had inhaled at least 1.6 x 10-6 spores/g of lung tissue at each of 6 exposures or 1.8 x 10-6 spores at 2 exposures. a single exposure to 3.6 x 10-5 spore ...	1975	807135
2-phenethylimidazole derivatives. synthesis and antimycotic properties.	compounds of type (x = o, nh; ar and ar' = phenyl of substituted phenyl; ten examples) were prepared and assayed against miconazole (ii,x = o; ar = ar' =2,4-cl2c6h3) as potential antimycotic agents. optimal activity was noted for i(x = o; ar = ar' = 2,4-cl2c6h3), the direct analog of miconazole. it is about one-tenth as active.	1975	807735
study of atmospheric fungi in a big cereal silo over a period of one year.	a quantitative and qualitative study of the atmospheric fungi in a big silo was carried out over a period of one year (april 1973--april 1974). about 6 to 12 petri dishes with czapek medium were exposed for 5 minutes every month at different floors of the silo. the study showed:--a very high number of fungi colonies, reaching as many as 903 in march 1974 (a total of 60 min exposure); the dominant fungus was penicillium which was, however, overpassed in certain months by aspergillus (flavus and f ...	1975	810877
the general and specific humoral immune response to pulmonary aspergillosis.	the genus aspergillus may cause one of several clinical entities in affected patients. serum specimens from 79 patients, including 41 with aspergilloma, 28 with allergic bronchopulmonary aspergillosis, 3 with both aspergilloma and the allergic variant, and 7 with invasive or disseminated aspergillosis, were studied for antibodies to aspergillus. the ammonium sulfate test was used with a mycelial component labeled with iodine-125 derived from aspergillus fumigatus. complement fixation and immunod ...	1975	812400
detection of aspergillus fumigatus serum precipitins by counterimmunoelectrophoresis.	detection of serum precipitins to aspergillus fumigatus by counterimmunoelectrophoresis is compared with the immunodiffusion technique. eight of nine (89%) sera from patients with proven a. fumigatus infection were positive by both methods. no serum from subjects with other systemic mycoses, bacterial infections, or healthy controls had detectable precipitins. the highest serum precipitin titers were found in sera of patients with the mycetomal and invasive forms of the disease. detection of a. ...	1975	812884
counterimmunoelectrophoresis as a routine mycoserological procedure.	counterimmunoelectrophoresis (cie) has been compared in a diangostic laboratory with agar gel double diffusion (dd) as a routine procedure for detection of antibodies to pathogenic and allergenic fungi and actinomycetes. it was shown to be of particular value in detecting antibodies to aspergillus fumigatus. thus 72 of 106 sera in which precipitins were detected were positive by cie alone. some sera were positive only by cie to antigens prepared from histoplasma capsulatum, allescheria boydii, c ...	1975	813146
hemolytic, cytotoxic and complement inactivating properties of extracts of different species of aspergillus.	some of the biological properties of saline extracts of the mycelia of several species of the aspergillus genus, namely, a. fumigatus, a. flavus, a. niger, a. nidulans, a. parasitucus and a. glaucus, were studied. only the extract prepared from a. fumigatus was found to be hemolytic for sheep red blood cells. in contrast, all the extracts with the only exception of that of a. glaucus, had cytotoxic effects on vero cells. both, the hemolytic and cytotoxic constituents of the extracts were removab ...	1975	813147
[on the prevalence of toxigenic aspergillus flavus strains in soviet-made food products].	an analysis of 813 specimens of agricultural crops and 155 specimens of good quality products from retail trading establishments demonstrated that more than 50 per cent of them were contaminated with molds of the a. flavus species. from among 489 strains isolated the toxigenic ones comprised 5.1 per cent and according to their morphological characteristics they were referred to molds of the a. flavus and a. fumigatus and penicillium species. toxigenic strains were isolated only in specimens of a ...	1975	813386
fungal air spora at ibadan, nigeria.	the fungal air spora at ibadan, nigeria, was investigated by using casella slit samplers. three sites, incorporating three locations at each site, were selected for the exposure of replicate plates during sampling. to provide data on a wide range of saprophytic and pathogenic fungal spores, isolations were made on sabouraud dextrose agar and malt agar plates incubated at 26 and 37 c. altogether over 60,000 fungal colonies were isolated and counted during the 12-month sampling period. the prevale ...	1975	1124919
an analysis of skin prick test reactions in 656 asthmatic patients.	of 656 asthmatic patients referred specifically for allergy assessments, 544 (84 percent) gave positive immediate skin prick tests to at least one of 22 common allergens used routinely. comparison of these skin test positive patients with the 102 (16 percent) who were skin test negative showed a number of significant differences. the majority of the skin test positive patients (52 percent) were less than 10 years old at the time of onset of the asthma, whereas, of the skin test negative patients ...	1975	1168378
deep mycotic infection in the hospitalized adult: a study of 123 patients.	a prospective study of patients hospitalized in a large veterans administration hospital between november 1963 and november 1973 revealed 123 patients with deep mycotic infections. the incidence of these infections almost doubled during the last 5 years. candida (55 patients) and aspergillus (26 patients) were the major causative agents. nine other fungal caused infection in the remaining patients. candidemia was rare prior to the introduction of commerical percutaneously-inserted venous cathete ...	1975	1186493
incidence of serum precipitins against organic-dust antigens in different populations by counterimmunoelectrophoresis.	the incidence of serum antidust and antifungal precipitins was determined by counterimmunoelectrophoresis in 317 atopic and nonatopic subjects of three geographic areas (north central, southern, and western united states). the selected lyophilized crude antigens employed were from house dust, micropolyspora faeni, candida albicans, alternaria tenuis, aspergillus fumigatus, puccinia coronata, cantharellus cibarius, and amborsia trifida. antidust precipitins were detected with high frequency in at ...	1975	1192851
immunological features of asthma (part ii). a report to the research committee of the british thoracic and tuberculosis association.	a serological comparison was made of two groups of 120 matched asthmatic and healthy subjects, between the ages of 20 and 49 years and matched for age and sex, in terms of serum total levels of igg, igm, iga, igd and ige and of specific antibody levels in each immunoglobulin class to five common uk allergens. the relationship of clinical features to the serological tests was also examined in the asthmatic subjects. the following statistically significant findings were shown. the patients had hig ...	1975	1053440
aspergillosis of bone.		1975	1089024
[incidence of aspergillosis in ex-coal miners suffering from pneumoconiosis].		1975	1089079
allergic bronchopulmonary aspergillosis: evidence of limited tissue invasion.	the cause of granulomatous parenchymal reaction in allergic bronchopulmonary aspergillosis has been attributed to a hypersensitivity reaction. a case is reported with aspergillus fumigatus identified in lung tissue, suggesting that the pathologic changes in some cases can be due to limited parenchymal colonization.	1975	1089377
humoral and cellular immunity in asthma.	parameters of humoral and cellular immunity have been measured in 91 asthmatic patients. mean serum levels of igg and ige were raised. igg levels were higher in those with a family history of asthma. ige levels were higher in those with a past history of atopic eczema, but intrinsic and extrinsic asthma could not be differentiated on the basis of ige levels. thirteen of 74 patients failed to respond to tetanus immunization, while only 1 failed to respond to salmonella typhi h antigen. tetanus no ...	1975	1089697
occurrence of thermophilic microorganisms in peanuts and peanut soil.		1975	1089873
ige antibodies to dermatophagoides pteronyssinus (housedust mite), aspergillus fumigatus, and beta-lactoglobulin in sudden infant death syndrome.	the prevalence of serum ige antibodies to dermatophagoides pteronyssinus (house-dust mite), aspergillus fumigatus, and bovine beta-lactoglobulin was significantly greater in cases of sudden infancy death (s.i.d.) than in a control group of infants of the same age range. this difference was most pronounced with d. pteronyssinus antibodies, which suggests that hypersensitivity to house-dust mite may be a factor in the aetiology of s.i.d. in western australia. both the s.i.d. and control infants ha ...	1975	1090327
[aspergillosis as a postoperative complication of a jaw cyst].		1975	1090912
aspergillus infection of the nasal cavity of the dog: diagnosis and treatment.		1975	1091084
endogenous aspergillus endophthalmitis occurring after kidney transplant.	two months after renal transplantation, a 26-year-old man developed pneumonia that was recalcitrant to antibiotic therapy and proved by biopsy to be due to cytomegalovirus and aspergillus fumigatus. ten days later while on amphotericin b therapy, he developed an endophthalmitis proved by smear and culture of a vitreous aspiration to be caused by a. fumigatus. despite intravitreous and systemic amphotericin b the vision deteriorated and the eye was enucleated. microscopic examination disclosed an ...	1975	1092176
characteristics of immunity in fungal infections.		1975	1092228
bronchocentric granulomatosis, mucoid impaction, and hypersensitivity reactions to fungi.		1975	1092235
cavitary pulmonary cryptococcosis complicated by aspergilloma.	a roentgenogram of a 31-year-old office worker who had developed pleuritic pain showed multiple abscess cavities in the left lower lobe, and a clinical diagnosis of cryptococcosis was considered because of cryptococci recovered from a sputum smear and a positive indirect fluorescent antibody test. lobectomy (after unsuccessful amphotericin therapy) proved the presence of a destructive cryptococcosis with aspergillus proliferating in the cavities.	1975	1092237
toxigenic thermophilic and thermotolerant fungi.	twenty-three isolates of fungi, representing 13 thermophilic and thermotolerant species, were bioassayed for toxigenicity to brine shrimp, chicken embryos, and rats. thirteen isolates representing nine genera were highly toxic to at least two of the three systems. seven additional isolates of five genera were slightly toxic.	1975	1092262
keratomycosis in lucknow.		1975	1092323
effect of auxins and herbicides on enhancement of protein synthesis in fungi.		1975	1094049
primary interaction between antibody and components of alternaria. ii. antibodies in sera from normal, allergic, and immunoglobulin-deficient children.	antibodies in sera from normal, allergic, and immunoglobulin-deficient children were studied for binding to radiolabeled components of alternaria tenuis. significant binding levels were found in 103 of 105 sera from normal children. the levels were age-dependent, rising from a low point in the 7- to 12-month age group to adult levels by the age of 8 years. levels of binding to two antigens, a culture filtrate derivative (125i-clf) and a mycelial derivative (125-i-hs), were similar. sera from ast ...	1975	1094055
letter: pulmonary aspergillosis, inhalation of contaminated marijuana smoke, chronic granulomatous disease.		1975	1094876
experimental aspergillosis in rats infected via intraperitoneal and subcutaneous routes.	normal adult rats infected via the subcutaneous (s.c.) route with viable spores of aspergillus fumigatus develop serum antibodies, measured by passive haemagglutination and passive cutaneous anaphylaxis (pca), to extracts of the fungus. no significant histological abnormality was detected but s.c. inoculation in cortisone-treated animals induced the formation of granulomas frequently found in lymph nodes including those of the mesentery and paratracheal group. these granulomas were associated wi ...	1975	1095475
polyene sensitivity during germination of conidia of aspergillus fumigatus.	a system for the rapid and relatively synchromous germination of conidia from a clinical isolate of aspergillus fumigatus is described. the polyene-mediated release of k plus from germinating conidia has been determined. ungerminated conidia were insensitive to amphotericin b methyl ester (ame) at concentrations greater than 50 mug/ml, but rapidly became sensitive to 1 to 2 mug ame/ml during the intitial stages of germination. these findings have been correlated with minimum inhibitory concentra ...	1975	1095686
effect of aflatoxin on phagocytosis of aspergillus fumigatus spores by rabbit alveolar macrophages.	rabbits were given dialy doses of aflatoxin b1 equivalents of 0.03, 0.05, 0.07, and 0.09 mg for a 2-week period. macrophages were harvested at the end of the experimental period, and in vitro phagocytosis experiments were conducted using aspergillus fumigatus spores as ingestion particles. alveolar macrophages from rabbits given the above doses of aflatoxin had reduced phagocytic activity when compared with macrophages from control rabbits. incorporation of serum from the aflatoxin-treated rabbi ...	1975	1096823
cerebral aspergillosis with special reference to cerebrospinal fluid findings.	a case of cerebral aspergillosis in a 69-year-old diabetic man is reported. the disease, initially presenting as headache and vertigo, was caused by aspergillus fumigatus. seven csf specimens were examined. the main findings included decreased glucose and increased protein concentrations, leukocyte reaction and one positive culture for a. fumigatus. neuropathological examination revealed granulomatous leptomeningitis and typical fungal hyphae. the process probably lasted for more than 1 year and ...	1975	1097253
rast studies : ige antibodies to dermatogoides pteronyssinus (house dust mite), aspergillus fumigatus and beta-lactoglobulin in sudden death in infancy syndrome (sdis).	the incidence of 2.5 sdis cases per 1,000 live births found in western australia is in agreement with figures reported for other centres. while the age range of sdis victims extended from two weeks to 15 months, 57 per cent of deaths occurred in children of two to four months of age. boys outnumbered girls 1.6:1. environmental factors are implicated in that the majority of deaths occurred in a biphasic distribution - autumn and late winter months. no significant differences were observed in tota ...	1975	1097279
experimental aspergillosis in normal rats infected intravenously.		1975	1097677
fatal aspergillosis in imported parrots.	spontaneous fatal aspergillosis occurred in several species of parrots imported from latin america, australia, malaya and ghana for studies on the control of psittacosis. over a period of 4 years, 655 parrots were imported for use in these studies. all birds that died during these investigations were necropsied, and the internal organs of 45 were found to have macroscopic lesions suggestive of aspergillosis. of these 45 suspected cases, 32 were confirmed as aspergillosis by both histopathology a ...	1975	1097931
letter: roentgenographically atypical pneumocystis carinii pneumonia.		1975	1098535
kinetic studies on the specificity of chelate-iron uptake in aspergillus.	three strains of the fungus aspergillus, aspergillus quadricinctus (e. yuill), a. fumigatus (fresenius), and a. melleus (yukawa), each producing different iron-chelating compounds during iron-deficient cultivation, were used for 55fe3+ uptake measurements. iron from chelates of the ferrichrome-type family was taken up by young mycelia of all strains tested, irrespective of the ferrichrome-type compound these strains predominantly produce in low-iron cultures. ferrichrysin-producing strains, howe ...	1975	1099079
immunoglobulin classes of antibodies to aspergillus fumigatus in patients with pulmonary aspergillosis.	an indirect immunofluorescence test was used to determine the titre and immunoglobulin classes of antibodies to aspergillus fumigatus in human serum. in 15 patients with aspergillosis, significant titres of igg but not iga or igm antibodies were found. the igg, iga and igm fractions of serum from 2 patients with aspergillosis were separated. this confirmed that antibodies to a. fumigatus reside in highest titre in the igg fraction. precipitating antibodies to a. fumigatus in these patients also ...	1975	1099699
detection of fungi in clinical specimens by phase-contrast microscopy.	during 1973 and 1974, the following fungi were detected in clinical specimens by using phase-contrast microscopy: blastomyces dermatitidis, 5; coccidioides immitis, 3; cryptococcus neoformans, 11; other yeasts 918; dermatophytes, 863; mucor species, 1; and aspergillus fumigatus, 16. this technique allows rapid detection and, in many instances, immediate identification of fungi in clinical specimens.	1975	1100675
a new pathogenic species of aspergillus in the aspergillus fumigatus series.		1975	1101054
bronchial asthma in the nigerian savanna region. a clinical and laboratory study of 106 patients with a review of the literature on asthma in the tropics.	one hundred and six asthma patients were studied in zaria in the nigerian savanna region. this group resembled hospital attenders in general in containing a disproportionately large number of immigrants from southern nigeria and students undergoing higher education. childhood asthma was rare. asthma started after the age of 19 years in 69 per cent of patients. twenty-seven per cent gave a history of rhinitis but none had had eczema. twenty-two per cent gave a family history of asthma. cutaneous ...	1975	1101285
[aspergillus infection in skin transplantation and its therapy].	in a 10 years old girl sustaining a corrosive injury of the lower leg from sulphuric acid, in the region of a skin transplantation colonization with aspergillus fumigatus (fresenium) and aspergillus niger (van tieghem) took place. this infection endangered the attempt of transplantation and the saving of the foot. treatment by medication with nystatin (moronal) and canesten (clotrimazol) were ineffective. pimaricin (pimafucin, natamycin) quickly erradicated the mycotic infection and secured an u ...	1975	1102271
experimental aspergillus endocarditis in rabbits.	aspergillus endocarditis in man usually occurs on prosthetic cardiac valves and gives rise to large vegetations which embolize easily producing peripheral organ infarction and infection. blood cultures are usually sterile and the disease is difficult to cure with antimicrobial agents. aspergillus endocarditis was studied in rabbits to determine the course, degree of fungemia, and response to treatment with amphotericin b (a), 5 flucytosine (5 fc) or a + 5 fc. polyethylene tubing was introduced i ...	1975	1102621
aspergillus antibody in patients with cystic fibrosis.	the respiratory flora of patients with cystic fibrosis (cf) frequently includes aspergillus, and 30% of their serum samples have been observed to contain precipitating antibody to this fungus. serum from 61 cf patients, 60 healthy persons, and three patients with cf and allergic bronchopulmonary aspergillosis was studied, using a quantitative assay for antibody to a fumigatus. although cf patients had significantly higher levels of aspergillus antibody, some antibody was found in all serum sampl ...	1975	1103615
pulmonary eosinophilia after substitution of aerosol for oral corticosteroid therapy.	three patients with chronic asthma developed pulmonary eosinophilia while oral prednisolone was being withdrawn after the introduction of treatment with beclomethasone dipropionate aerosol. these observations suggest that the development of pulmonary eosinophilia in patients with chronic asthma can be prevented by the systemic administration of corticosteroids, but not by a corticosteroid aerosol given by inhalation. it is considered that radiological examination of the chest should be carried o ...	1975	1103929
effect of tweens on the production of ergot alkaloids by aspergillus fumigatus.	tween 80, which caused increased biomass formation, also produced the highest increase in the uptake rate of all components of the medium. the fatty acid components of the respective tweens, i.e. palmitic acid (tween 40), stearic acid (tween 60), and oleic acid (tween 80), have no effect either on alkaloid production or on substrate uptake. the fatty acid composition was different in the cell membrane of the culture supplemented with tween 60 and facilitated the transport of metabolites into the ...	1975	1104424
chitin assay used to demonstrate renal localization and cortisone-enhanced growth of aspergillus fumigatus mycelium in mice.	aspergillus fumigatus mycelium in untreated mice (n-mice) and cortisone acetate-treated mice (c-mice) has been quantified by chemical assay of fungal chitin. cortisone pretreatment rendered mice more susceptible to infection by a. fumigatus (mean lethal dose at 20 days, congruent to 10(6) for n-mice; less than 10(4) for c-mice). in both n- and c-mice there was renal localization of mycelial infection at conidial doses less than the mean lethal dose. at a conidial dose greater than the mean letha ...	1975	1104488
[immunological responses to cultural filtrates in guinea pigs sensitized to aspergillus fumigatus and candida albicans].		1975	1104918
inhibition of tryptophan synthetase by phosphate in alkaloid-producing culture of aspergillus fumigatus.		1975	1105205
[study of the fertility of bull sperm contaminated with aspergillus fumigatus spores].	tested was the penetrating capacity of 55 samples of bulls' semen, contaminated with aspergillus fumigatus, so far as the estrous secretion of cows was concerned. a total of ten cows in heat were inseminated with spermatozoa carrying the aspergillus spore infection. it was found that the contaminated semen was with deteriorated quality and a 50 per cent lowered penetrating capacity as against the controls. the inseminated cows conceived with difficulty, exhibited disturbances in their sexual cyc ...	1975	1105957
[diagnostic scheme of the causes of embryonal morbidity in poultry].	a diagnostic scheme has been worked out to reveal the factors causing higher embryonic morbidity and mortality rates in birds. it is based on the morphologic analysis and the bacteriologic and mycologic studies, and can be programmed and put into effect in three stages in the course of 48 hours. on the one hand, the post-mortem analysis is useful in establishing the factors of noninfectious character (overheating, insufficient heating, humidity of low or high values, poor air exchange, improper ...	1975	1108408
diagnosis and management of orbital aspergillosis.		1976	1108734
the pathogenesis of experimental pulmonary aspergillosis in normal and cortisone-treated rats.	normal outbred adult wistar rats were resistant to infection with intratracheally administered viable spores of aspergillus fumigatus although although they developed a subacute interestitial pneumonia. while the lesions were more severe in animals immune suppressed with azathioprine (immuran) there was no evidence of hyphal growth in the pulmonary tissue. significant histological involvement was found only in those animals receiving repeared subcutaneous injections of cortisone and multiple int ...	1976	1255306
infection and mortality in captive wild-trapped canvasback ducks.	fungal, bacterial and malarial infections, as well as malnutrition caused heavy mortality in a group of wild-trapped canvasbacks (aythya valisineria) held in 10 x 3 x 2 m open-water pens. deaths occurred between 21 and 158 days after confinement and were associated with infections of aspergillus fumigatus, escherichia coli, staphylococcus sp., streptococcus sp., klebsiella sp., enterobacter sp., and plasmodium sp. infection and mortality was believed to result from reduced resistance associated ...	1976	1255909
cell-mediated immunity in patients with cystic fibrosis.	leucocytes from 26 patients with cystic fibrosis (cf) and 18 healthy controls were investigated by migration inhibition induced by a variety of antigens. in patients with cf cell-mediated immunity was found to human lung and pancreatic tissue extracts as well as to aspergillus fumigatus, pseudomonas aeruginosa, and food antigens but not to brain, heart, or kidney. those patients with the severest form of the disease had the greatest impairment of cell-mediated immunity, but this impairment could ...	1976	813805
effect of cetylpyridinium chloride on pathogenic fungi and nocardia asteroides in sputum.	the effect of cetylpyridinium chloride (cpc) on pathogenic fungi and nocardia asteroides was studied. sputa seeded with each of 11 organisms (aspergillus flavus; aspergillus fumigatus, blastomyces dermatitidis, candida albicans, coccidioides immitis, cryptococcus neoformans, geotrichum candidum, histoplasma capsulatum; nocardia asteroides, paracoccidioides brasiliensis, and sporothrix schenckii) were treated with cpc and kept for 2, 5 and 9 days. the cpc reagent used (0.5% cpc and 0.5% sodium ch ...	1976	773957
mycotic aneurysm of the thoracic aorta caused by aspergillus fumigatus.	a 54-year-old diabetic patient had unexplained fever and embolic occlusion of the splenic, right renal, right hypogastric, right superficial femoral, and left popliteal arteries. aspergillus fumigatus was recovered from a femoral clot. an aortogram revealed a mycotic aneurysm of the thoracic aorta to be the source of the infected emboli. surgical excision of the aneurysm and therapy with amphotericin b were unsuccessful.	1976	776547
acquired immunity to aspergillus fumigatus.	in mice preinfected with aspergillus fumigatus for greater than or equal to days, administration of cortisone failed to stimulate mycelial growth. the liver and heart of mice preinfected for 14 days resisted infection after a cortisone + conidia challenge.	1976	776836
morphogenesis and pathogenesis of chronic lung diseases. viii. cellularization of lung interlobular areas as a preliminary phase of peribronchovascular fibrosis.	an experimental investigation of the lung interlobular areas was performed by elicitation of rabbits with antigens (aspergillar and human-serum proteins) administered in aerosols or intramuscularly in freund's adjuvant. the cell accumulations in the interlobular areas developed irrespective of the antigen, duration of exposure and route of administration. the cells accumulated (reticulo-lymphoid, plasma cells, eosinocytes) were counted and the areal surface measured. the total cell count and the ...	1976	772786
the relative susceptibility of new zealand black and cba mice to infection with opportunistic fungal pathogens.	the susceptibility of ageing new zealand black (nzb) mice to infection with a number of opportunistic fungi and yeasts wsd compared with that of similarly aged mice of the cba strain. the nzb mice showed a greater susceptibility to lethal infection with aspergillus fumigatus, candida albicans and cryptococcus neoformans than did those of the cba strain. both mouse strains showed similar susceptibility to lethal infection by allescheria boydii, absidia corymbifera, mucor pusillus and rhizopus ory ...	1976	772839
pleural aspergillosis: a case report.	the first case of pleural aspergillosis on either american continent since 1958 is reported. the recent literature is reviewed. the pleura is infected by aspergillus through bronchopleural or pleurocutaneous communication. surgical removal of aspergillus infected pleura is the cornerstone of therapy.	1976	773232
hatchery problems--a field report.	a long term investigational, advisory and monitoring exercise with a major hatchery emphasised the multi-disciplinary approach adopted by the agricultural development and advisory service (adas) to raise the performance of the many aspects of chick production. these included an investigation of egg handling techniques from nest box to hatcher; the adoption by the hatchery of plastic setter trays; an improvement to incubator environment; an improvement in the overall hatchery hygiene programme an ...	1976	769299
[experimental abortions in mice and guinea pigs caused by aspergillus fumigatus spores].	experiments were carried out with a total of 82 laboratory animals including 56 mice and 26 guinea pigs. the possibility was tested to provoke abortions in them with the use of aspergillus fumigatus spores introduced through the trachea, orally or vaginally. the mould was isolated on chapek agar from an aborted bovine fetus. it was found that all three routes of infection lead to abortions setting in after three to five treatments on the 1st to 3rd day following the last introduction of spores. ...	1976	769306
mechanism of uptake of strontium isotopes in aspergillus lesions.	observations on experimental aspergillosis of chorioallantoic membranes confirmed that strontium-85 uptake in aspergillus lesions was directly due to infection by the fungus. such uptake was not found in normal or in toxoplasma gondii-infected control membranes. further, the avidity of radionuclide uptake was proportional to the mycelial mass, as previously observed clinically. investigations on 85sr containing malt extract broth aspergillus fumigatus cultures revealed that fungal hyphas did not ...	1976	769615
conditional virulence of a p-aminobenzoic acid-requiring mutant of aspergillus fumigatus.	the induced auxotrophy for p-aminobenzoic acid (paba) resulted in a complete loss of virulence of aspergillus fumigatus for normal as well as cortisone-treated mice. the paba-requiring mutant of a. fumigatus survived in vivo for 4 to 7 days without causing any infection. however, it showed conditional virulence in animals receiving paba in very small quantities. repeated inoculations of the viable spores of the avirulent mutant strain gave favorable results in building immunity against intraveno ...	1976	770331
intravitreal effects of pimaricin in experimental fungal endophthalmitis.	evaluation of 25, 50, and 100 mug of pimaricin given intravitreally to albino rabbits with aspergillus endophthalmitis revealed that 25 mug of pimaricin, while nontoxic to the retina, was ineffective in inhibiting the fungal process. a dose of 50 mug was significantly more effective in inhibiting fungal disease but also caused significant retinal damage with loss of retinal function and iridoplegia. dosages above this level resulted in vitreous retraction and degeneration, iridoplegia, and retin ...	1976	766638
immunologic monitoring and aspergillosis in renal transplant patients.	three cases of pulmonary aspergillosis in a "high risk" population of renal transplant recipients are presented. the source of infection was traced to the forced air exhaust system of the transplantation unit. early definitive diagnosis of the infection was very important for effective management. immunologic monitoring was demonstrated to be instrumental in indicating the early presence of infection, and as a guideline to reduced immunosuppression during therapy. bronchoscopy with brushings and ...	1976	766657
bronchopulmonary aspergillosis. an epidemiological study in a hospital population.	in order to determine the incidence of bronchopulmonary aspergillosis in patients with other types of pulmonary pathology, 586 in-patients, out-patients and controls were examined during the period 1968-1970 in baguley hospital, manchester, england. it was found that from the 344 in-patients and out-patients with other pulmonary pathology, 6 had a definite diagnosis of allergic aspergillosis. 1 had pulmonary aspergilloma while 53 other patients demonstrated some evidence of bronchopulmonary aspe ...	1976	778964