Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| periodontopathogens in elderly chinese with different periodontal disease experience. | if an etiological relationship exists between destructive periodontal disease and putative periodontopathogens, they would be expected to have a very low prevalence in periodontally healthy elderly persons. to test this hypothesis, 2 subgroups of elderly, rural chinese (a periodontally "best" and a "worst" group, each comprising 15 persons) were identified in 1990 from a cohort aged 55-69 years, examined in 1984. assessment of changes in periodontal status over the 6-year period were possible by ... | 1995 | 7790524 |
| properties of alkaline phosphatase in the gingival crevicular fluid. | the isoenzymic properties of the alkaline phosphatase (alp) of the gingival crevicular fluid (gcf) were investigated and compared with those in other cells, such as human polymorphonuclear leukocytes (pmns), and human periodontal ligament cells (pdls), and with those of three species of periodontopathic bacteria: porphyromonas gingivalis 381 (p. gingivalis), prevotella intermedia atcc25611 (p. intermedia), and capnocytophaga sputigena atcc33123 (c. sputigena). the biochemical properties of the i ... | 1995 | 7796488 |
| studies into the microbial spectrum of apical periodontitis. | this study examined the variety of obligate and facultative anaerobic bacterial species recovered from cases of acute apical periodontitis. a total of 19 root canal samples and 24 periapical granuloma samples were taken from patients suffering pain and discomfort. bacteria were identified by applying the following techniques: culturing on various media, gram-staining and using commercially available biochemical test strips. in addition, prevotella intermedia and porphyromonas endodontalis were d ... | 1995 | 8626206 |
| [treatment of diversion colitis with short-chain fatty acids. bacteriological study]. | bacterial imbalance may be involved in the pathogenesis of diversion colitis, via diminished production of short chain fatty acids. the aim of the study was to evaluate the effectiveness of short chain fatty acids on microbial flora of patients with diversion colitis and to compare this flora to the microbial flora of controls. | 1995 | 8746044 |
| effect of titanium on selected oral bacterial species in vitro. | titanium granules were tested for their antibacterial effect on strains of streptococcus sanguis, streptococcus mitis, actinomyces naeslundii, haemophilus parainfluenzae, fusobacterium spp. and prevotella intermedia in comparison with amalgam and two of its components, copper and tin. glass beads were used as controls. the number of viable bacteria was estimated in samples exposed to the various materials for 1, 3, 6 and 24 h, respectively, and the viable counts were related to the baseline valu ... | 1995 | 8747674 |
| [subgingival plaque due to gingivitis and inactive periodontitis sites in the adult periodontitis patient]. | there are several discrepancies with respect to the composition of subgingival plaque in gingivitis and in inactive adult periodontitis (ap). in this study we compared subgingival plaque samples taken from gingivitis sites to those from inactive periodontitis sites of the same patients. of 44 patients plaque samples from 86 gingivitis sites and 92 periodontitis sites were analysed. darkfield microscopy showed a higher proportion of spirochetes and mobile rods in the periodontitis sites. analysis ... | 1995 | 7878415 |
| antimicrobial susceptibility of periodontopathic bacteria associated with failing implants. | the aim of this study was to examine the subgingival microflora associated with failing implants, and to determine their susceptibility to commonly used antibiotics in periodontal therapy and dental practice. thirteen partially edentulous patients with 19 failing implants were selected. clinical examination included probing depth, attachment level, gingival index, plaque index, and radiographic analyses. two subgingival plaque samples were taken from each failing implant and analyzed for microbi ... | 1995 | 7891253 |
| antibody responses to suspected periodontal pathogens in elderly subjects with periodontal disease. | little is known about the relationship of aging to periodontal disease. the immune response undergoes aging-related changes resulting in loss of functional capacity. the aim of this study was to investigate the relationship between levels of serum igg antibodies against suspected periodontal pathogenic microorganisms to the presence or absence of periodontal disease in an elderly (65-75 yrs) population. from this study, we obtained information concerning: (1) the ability to differentiate elderly ... | 1995 | 8550860 |
| putative periodontal pathogens colonizing oral mucous membranes in denture-wearing subjects with a past history of periodontitis. | the prevalence of selected putative periodontal pathogens colonizing oral mucous membranes was investigated in 26 denture-wearing subjects with a history of periodontitis. the microbiota of the oral cavity of these subjects was examined on average 9.3 years after extraction (range: 1-40 years). samples were taken from several locations on the oral mucous membranes, from saliva and from plaque attached to the upper and lower denture. actinobacillus actinomycetemcomitans was not detected in any of ... | 1995 | 8550862 |
| the subgingival microflora and gingival crevicular fluid cytokines in refractory periodontitis. | refractory periodontitis manifests as a rapid, unrelenting, progressive loss of attachment despite the type and frequency of therapy. this study examined possible relationships between cytokine levels in gingival crevicular fluid (gcf), occurrence of specific periodontopathic microflora, and disease activity in patients with refractory periodontitis. refractory periodontitis patients (7 male and 3 female) were selected on the basis of history and longitudinal clinical observations. in each patie ... | 1995 | 8550866 |
| necrotizing ulcerative gingivitis, periodontitis, and stomatitis: clinical staging and predisposing factors. | necrotizing ulcerative gingivitis (nug), necrotizing ulcerative periodontitis (nup), and necrotizing stomatitis (ns), collectively termed necrotizing gingivostomatitis (ng), represent a dramatic, but rare oral infection associated with diminished systemic resistance, including hiv infection. over a 5-year period, 68 consecutive ng patients from a population with known hiv status were evaluated and treated. lesions were staged (modified pindborg), and clinical findings and predictor variables wer ... | 1995 | 8558402 |
| oral microbiota in subjects with a weak or strong response in experimental gingivitis. | the purpose of the present study was to examine the composition of the oral microbiota in subjects who had previously demonstrated to develop either a weak or strong response to experimental gingivitis. for this study, subjects were selected from a pool of 25 individuals who had participated twice in an experimental gingivitis trial. out of these 25 panellists, 6 subjects were selected who had developed 2x a weak gingival inflammatory response and 7 subjects who had developed 2x a strong gingiva ... | 1995 | 8583022 |
| [subgingival distribution of periodontopathic bacteria in periodontic patients and susceptibility of these bacteria to minocycline-hcl]. | the present study was carried out to examine the distribution of six periodontopathic bacteria in deep periodontal pockets and to reconfirm the effect of periocline on these periodontopathic bacteria. samples from sixty-two periodontal pockets were collected at pocket depths of over 4 mm in twenty-one periodontitis patients aged 43 to 75 years. after sampling, periocline was applied topically to the selected pockets once a week for four weeks and reexamined. the detected rates of the periodontop ... | 1995 | 8583161 |
| [effects of the prevotella intermedia culture filtrate and short-chain fatty acids on human polymorphonuclear neutrophil functions]. | anaerobes, in particular prevotella spp., are the predominant bacteria present in mixed respiratory infections. to study the virulence factor of prevotella intermedia, we examined the effects of the culture filtrate of p. intermedia on the bactericidal activity of human polymorphonuclear neutrophils (pmns). the culture filtrate significantly inhibited the phagocytic killing and the intracellular killing of staphylococcus aureus by pmns (p < 0.05), but the phagocytosis of pmns was not affected. t ... | 1995 | 8586886 |
| confirmation of the species prevotella intermedia and prevotella nigrescens. | the elevation of the two genotypes of prevotella intermedia to species rank as p. intermedia and prevotella nigrescens has increased the need for reliable differentiation between the two taxa. in this study, 53 strains, including strains whose species affiliations were known as well as fresh dental plaque isolates, were subjected to a multilocus enzyme electrophoretic analysis, dna analyses in which we used whole genomic dna, rrna sequences, and an oligonucleotide specific for the former p. inte ... | 1995 | 8590668 |
| postoperative healing complications associated with gore-tex periodontal material. part i. incidence and characterization. | guided tissue regeneration procedures with gore-tex periodontal material are associated with a unique set of postoperative healing characteristics. five healing complications are described in this study examining 102 sites. the occurrence of pain and purulence were the most common. in purulent sites, the majority of bacteria cultured were actinomyces and streptococcus spp. resistance to antibiotics was common. prevention and treatment of the healing complications are discussed. | 1995 | 8593986 |
| antimicrobial and toxic effects of established and potential root canal irrigants. | three dilutions of the commonly used irrigant sodium hypochlorite (0.5%, 2.5%, and 5.25%) and the potential irrigants peridex, chlorhexidine gluconate (0.12%), and therasol were tested. alcohol and saline served as controls also. the in vitro portion of this study used four different microorganisms (streptococcus mutans, peptostreptococcus micros, prevotella intermedius, and porphyromonas gingivalis) to determine antimicrobial effect. presterilized 7-mm diameter whatman paper disks soaked with t ... | 1995 | 8596073 |
| porphyromonas gingivalis outer membrane vesicles promote bacterial resistance to chlorhexidine. | porphyromonas gingivalis has been frequently associated with some types of periodontal diseases and possesses various mechanisms favoring the pathogenic process. it has been recently observed that vesicles elaborated by p. gingivalis are able to protect bacteria from the bactericidal activity of human serum. the aim of the present investigation was to evaluate the ability of vesicles from p. gingivalis in protecting oral bacteria against chlorhexidine. data indicate that vesicles released by p. ... | 1995 | 8596676 |
| microbial alterations in supragingival dental plaque in response to a triclosan-containing dentifrice. | a total of 325 subjects were entered into a double-blind, stratified 2-treatment clinical study that examined the effects of a dentifrice containing 0.3% triclosan, 2% gantrez copolymer and 0.243% sodium fluoride on supragingival dental plaque and gingivitis. a subset of 159 subjects including 72 men and 87 women participated in the microbiological component of this study, which was designed to detect shifts in supragingival bacterial species in response to triclosan. subjects were divided into ... | 1995 | 8602338 |
| cell envelope and cell wall immunization of macaca fascicularis: effect on the progression of ligature-induced periodontitis. | the nonhuman primate, macaca fascicularis, was used to study the role of immunization with selected members of the periodontopathic microbiota in the longitudinal progression of ligature-induced periodontitis. animals were immunized with cell envelope antigens prepared from porphyromonas gingivalis and prevotella intermedia, and a mixture prepared from fusobacterium nucleatum, campylobacter rectus, and actinomyces viscosus. serum immunoglobulin g (igg), igm and iga isotype antibodies increased s ... | 1995 | 8602339 |
| viability of four putative periodontal pathogens and enteric rods in the anaerobic transport medium vmga iii. | the aim of this study was to determine the survival in vmga iii of porphyromonas gingivalis, prevotella intermedia, fusobacterium nucleatum, actinobacillus actinomycetemcomitans and enteric rods in laboratory cultures as well as in subgingival plaque samples. laboratory strains of the 4 putative periodontal pathogens and escherichia coli were used in the laboratory part of this study. also, 31 subgingival plaque samples were obtained from 22 periodontal patients and stored in vmga iii. each samp ... | 1995 | 8602345 |
| colorimetric microtiter plate based assay for detection and quantification of amplified actinobacillus actinomycetemcomitans dna. | we developed a colorimetric microtiter plate-based assay for the detection and quantification of polymerase chain reaction-amplified dna fragment specific for actinobacillus actinomycetemcomitans. we amplified the 396-bp leukotoxin-specific dna fragment by using two oligonucleotide primers, one carrying a biotin group at the 5' end and another one with a digoxigenin at the 5' end. following amplification, the biotinylated polymerase chain reaction products were applied to a microtiter well preco ... | 1995 | 8602346 |
| lipopolysaccharides of oral black pigmented bacteria and periodontal diseases. a novel immunomodulator different from endotoxin was extracted from prevotella intermedia atcc 25611 with hot phenol-water. | 1995 | 8524965 | |
| salivary levels of suspected periodontal pathogens in relation to periodontal status and treatment. | the primary ecological niche for suspected periodontal pathogens seems to be the subgingival area, even though periodontal pathogens are also frequently recovered from saliva. the interrelationship of different periodontal conditions and the salivary levels of suspected periodontal pathogens is not known. in the present study, salivary levels of actinobacillus actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, campylobacter rectus, and peptostreptococcus micros were determin ... | 1995 | 8530742 |
| bacterial colonization of the external and internal sulci and of cellulose membranes at time of retrieval. | membrane exposure with bacterial contamination is often considered one of the main reasons for the lack of predictability in achieving complete regeneration of periodontal defects. ten cellulose membranes, retrieved from 7 patients treated for class ii furcation lesions in lower molars with at least 4 mm of exposure at time of retrieval were studied. contamination of exposed membranes was studied using sem analysis of four surfaces of the membrane, upper external, lower external, upper internal, ... | 1995 | 8537869 |
| in-vitro antibacterial effects of extracts of nigerian tooth-cleaning sticks on periodontopathic bacteria. | aqueous extracts from 8 plants used for tooth-cleaning in nigeria were tested for their ability to inhibit the growth of five periodontopathic bacteria, porphyromonas gingivalis, prevotella intermedia, fusobacterium nucleatum, eikenella corrodens and campylobacter rectus. extracts of all the plants except that of massularia acuminata exhibited varying growth inhibitory potentials on the microorganisms. extract of terminalia glaucescens showed the widest spectrum of activity, inhibiting the growt ... | 1995 | 9590895 |
| periodontal healing and periopathogenic microflora in smokers and non-smokers. | the aim of the present study was to monitor the clinical and microbiological effects of non-surgical therapy in smokers and non-smokers. the subject material included 32 patients (age range 32-61 years), 11 men and 21 women with moderate to severe periodontitis. 17 patients were smokers ( > or = 15 cigarettes/day) and 15 non-smokers. all patients were subjected to non-surgical periodontal therapy performed by a dental hygienist. periodontal variables (plaque index, gingival index and probing dep ... | 1995 | 8613564 |
| the laboratory diagnosis of periodontal infections. | 1995 | 9567931 | |
| the relation of microbiologic data to aspartate aminotransferase enzyme activity in gingival crevicular fluid. | gingival crevicular fluid (gcf), reflects the immune and inflammatory reactions and is itself a location for specific host-microbe interactions that lead to periodontal diseases. aspartate aminotransferase (ast) is one of the components of gcf that is released as a result of cell death. in this study, 40 periodontal sites in 10 early onset periodontitis patients before and after nonsurgical periodontal therapy, with and without local metronidazole administration, were first examined for the ast ... | 1996 | 9569804 |
| interleukin-8 gene expression by human dental pulp fibroblast in cultures stimulated with prevotella intermedia lipopolysaccharide. | interleukin (il)-8 mrna expression was investigated in human dental pulp fibroblast cultures after stimulation with lipopolysaccharide (lps) prepared from prevotella intermedia and inflammatory cytokines. the expression of il-8 mrna and the release of il-8 induced by p. intermedia lps in pulpal fibroblast cultures were detected by northern blot analysis and elisa, respectively. the sufficient concentration of p. intermedia lps on the il-8 mrna expression was 0.1 microgram/ml in pulpal fibroblast ... | 1996 | 8618087 |
| matrix metalloproteinases-1, -3 and -8 and myeloperoxidase in saliva of patients with human immunodeficiency virus infection. | human immunodeficiency virus (hiv)-seropositive patients have frequently severe gingival inflammation and/or attachment loss. in addition many infectious diseases affect their periodontium with varying clinical manifestations. matrix metalloproteinases seem to play a key role in physiological periodontal remodelling and pathological tissue destruction. the aim of the present study was to characterize the presence, molecular forms, cellular sources, activities, and relative amounts of fibroblast- ... | 1996 | 9171509 |
| hydrolytic and depolymerising enzyme activity of prevotella intermedia and prevotella nigrescens. | prevotella intermedia has been reported to be associated with periodontal disease whilst p. nigrescens has predominantly been isolated from more specific conditions and healthy sites. the aim of the present study was to compare the enzyme activity of these species. | 1996 | 9171510 |
| similarity of salivary and subgingival prevotella intermedia and prevotella nigrescens isolates by arbitrarily primed polymerase chain reaction. | the distribution and the genetic similarity of prevotella intermedia and prevotella nigrescens in saliva and in subgingival samples recovered from the same subject were studied in 16 subjects with different periodontal status. the isolates (4 salivary and 4 subgingival p. intermedia/nigrescens group isolates per subject) were identified to species level by hybridization with species-specific oligonucleotide probes, and the clonal analysis was performed using arbitrarily primed polymerase chain r ... | 1996 | 9467372 |
| associations of endodontic symptoms and signs with particular combinations of specific bacteria. | significant associations have been reported between (a) specific bacterial species isolated from root canals and (b) between individual bacterial species and endodontic symptoms and signs. the prime objective of this study was to determine whether particular combinations of specific bacteria are associated with individual endodontic symptoms and signs. seventy root canals were investigated microbiologically taking care to maintain the viability of obligate anaerobes, which accounted for 64% of t ... | 1996 | 9206427 |
| rapid differentiation of prevotella intermedia and p. nigrescens by 16s rdna pcr-rflp. | prevotella intermedia and the newly described p. nigrescens cannot be reliably distinguished by phenotypic tests. in this study, restriction endonuclease digestion of amplified 16s rdna (16s rdna pcr-rflp) was used to generate restriction profiles of the type strains of p. intermedia and p. nigrescens and 43 fresh isolates identified as belonging to one of the two species. whole-cell protein profiles were obtained by sds-page for comparative purposes. the type strains of p. intermedia and p. nig ... | 1996 | 8544210 |
| aerobic and anaerobic microbiology of superficial suppurative thrombophlebitis. | to study the aerobic and anaerobic microbiologic characteristics of superficial suppurative thrombophlebitis. | 1996 | 8546586 |
| prevotella intermedia fimbriae mediate hemagglutination. | our earlier studies demonstrated that clinical strains of prevotella intermedia, isolated from human periodontal pockets, possess various types of fimbria (surface appendages) as determined ultrastructurally. these bacteria have the ability to agglutinate selected mammalian erythrocytes. hemagglutinating activity exhibited by these cells may be attributable to these surface structures. strain 17, which possess fimbriae of 8 nm in diameter and readily agglutinates human, monkey, sheep, rabbit, an ... | 1996 | 8604254 |
| colonization by actinobacillus actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia in adult periodontitis patients as detected by the antibody-based evalusite test. | studies were performed to evaluate the detection of disease-associated bacterial colonization in adult periodontitis patients by the antibody-based evalusite testtm (eastman kodak company). the association of test results with disease was assessed by collecting 104 duplicate subgingival plaque samples from 26 patients. samples were tested for actinobacillus actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia using both microbiological culture and the immunoassay test. the s ... | 1996 | 8783055 |
| [in vitro activities of sulopenem, a new parenteral penem, against anaerobes]. | in vitro activities of sulopenem, a novel parenteral penem, was compared with those of imipenem, flomoxef, cefuzonam, cefoperazone and sulbactam/ampicillin against 66 reference strains (19 genera, 61 species) and 392 recent clinical isolates of anaerobic bacteria and fastidious aerobic bacteria. sulopenem had a very broad spectrum against anaerobic bacteria. in general, this compound was active against anaerobic reference strains with mics of < or = 0.78 micrograms/ml, while being the least acti ... | 1996 | 8786627 |
| treatment of periodontal disease based on microbiological diagnosis. relation between microbiological and clinical parameters during 5 years. | the purpose of this study was to assess the clinical effect of treatment aimed to suppress actinobacillus actinomycetemcomitans and porphyromonas gingivalis below detection level and prevotella intermedia below 5% of the cultivable periodontal pocket flora. sixteen patients and a total of 111 periodontal pockets with probing depth > or = 6 mm were included in the study. twelve patients and a total of 77 sites completed the 5-year study. the results demonstrated clinical improvement of probing de ... | 1996 | 8794965 |
| lipopolysaccharides from porphyromonas gingivalis, prevotella intermedia and actinobacillus actinomycetemcomitans promote osteoclastic differentiation in vitro. | bacterial lipopolysaccharides possess bone-resorbing activity. here, lipopolysaccharides from three putative periodontopathic bacteria were examined for effects on osteoclast-like cell formation of bone marrow cells from lipopolysaccharide-responsive c3h-hen and non-responsive c3h/hej mice. the bone marrow cells were cultured with or without various doses of lipopolysaccharide in the presence of 1,25-dihydroxyvitamin d3 and dexamethasone. these lipopolysaccharide preparations significantly incre ... | 1996 | 8809306 |
| binding and degradation of lactoferrin by porphyromonas gingivalis, prevotella intermedia and prevotella nigrescens. | the ability of laboratory and clinical strains of porphyromonas gingivalis, prevotella intermedia and prevotella nigrescens to bind and to degrade lactoferrin (lf) has been assessed. lf bound readily to whole cells of each species apparently via high-affinity site and one or more low-affinity sites. p. gingivalis showed a lower affinity for lf than the other two species (p < 0.001). virtually all strains of p. gingivalis completely degraded lf under the conditions employed, whereas p. intermedia ... | 1996 | 8809549 |
| phototoxicity of argon laser irradiation on biofilms of porphyromonas and prevotella species. | species of prevotella (pr.) and porphyromonas (po.) and other microorganisms were cultivated as biofilms on agar medium and examined for their susceptibility to argon laser irradiation (continuous mode; wavelengths, 488-514 nm; fluences, 20-200 j cm(-2)). fluences of 35 to 80 j cm(-2) inhibited biofilm growth in po. endodontalis, po. gingivalis, pr. denticola, pr. intermedia, pr. melaninogenica and pr. nigrescens. a fluence of 70 j cm(-2) did not affect biofilm growth in species of bacillus, can ... | 1996 | 8810530 |
| effects of cyclosporine a on plasma cells in experimental gingivitis in dogs. | the aim of the present investigation was to evaluate the effect of cyclosporine a (csa) on the inflammatory lesion formed in the gingival tissues during de novo plaque formation. 5 beagle dogs were used. on day 0, all teeth of the 5 dogs were scaled and polished. a 6-week period of plaque control including daily tooth cleaning with toothbrush and dentifrice was initiated. a clinical examination regarding plaque and gingivitis was performed, and the plaque control measures were abandoned on the r ... | 1996 | 8811468 |
| chemiluminescent assay of alkaline phosphatase in human gingival crevicular fluid: investigations with an experimental gingivitis model and studies on the source of the enzyme within crevicular fluid. | the purpose of this study was to investigate how levels of gingival crevicular fluid (gcf) alkaline phosphatase (alp) change in relation to levels of plaque and gingival inflammation in 20 adults during a 21 day period of experimental gingivitis. the source of alp within gcf was also investigated using a repeat sampling protocol; by determining enzyme levels derived from 30 putative periodontal pathogenic and non-pathogenic species; and by examining inhibition profiles from a variety of host and ... | 1996 | 8811480 |
| source of suspected periodontal pathogens re-emerging after periodontal treatment. | to clarify the source of re-emerging periodontal pathogens after treatment, we compared the ribotypes of actinobacillus actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia/prevotella nigrescens group and campylobacter rectus before and after treatment in 7 periodontitis patients and in 6 of the spouses. the patients harbored a. actinomycetemcomitans, p. gingivalis, p. intermedia/p. nigrescens group or c. rectus in their subgingival or salivary samples before treatment. the res ... | 1996 | 8811482 |
| occurrence of actinobacillus actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia in juvenile periodontitis. | the occurrence of actinobacillus actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia in subgingival plaque in 24 juvenile periodontitis patients was determined using dna probe. 36 samples of subgingival plaque from 36 pockets having > or = 6 mm depth, > or = 3 mm of loss of attachment, and bleeding on probing and/or suppuration were taken from 18 patients with localized juvenile periodontitis (ljp, age range 12-24 years); and 12 samples from 6 patients with generalized juve ... | 1996 | 8849845 |
| prevalence of 6 putative periodontal pathogens in subgingival plaque samples from romanian adult periodontitis patients. | the aim of the present study was to determine by standard cultivation procedures the detection frequencies of porphyromonas gingivalis, prevotella intermedia, fusobacterium nucleatum, actinobacillus actinomycetemcomitans, bacteroides forsythus, and capnocytophaga species as well as various enteric rods in subgingival plaque samples form romanian adult periodontitis patients. dna probe analysis (affirm dp microbial identification test) was also used, parallel to cultivation, to identify p. gingiv ... | 1996 | 8849850 |
| growth inhibition of a human oral bacterium porphyromonas gingivalis by rat cysteine proteinase inhibitor cystatin s. | agar diffusion analysis demonstrated that rat cystatin s, a cysteine proteinase inhibitor, inhibited the growth of all tested strains of a human oral, gram-negative anaerobic periodontopathogen porphyromonas gingivalis. its specific inhibitory activity against this tissue-invasive bacterium but not against other tested oral bacterial species emphasized the importance of specific cysteine proteinases for growth of p. gingivalis. | 1996 | 8862019 |
| osseointegrated implants in patients treated for generalized severe adult periodontitis. an interim report. | this study presents oral rehabilitation with osseointegrated implants in partially edentulous patients treated for generalized severe adult periodontitis. five female patients aged between 31 and 44 received a total of 36 implants and were observed for 1 year after insertion of the superstructure. three months before implantation, venous blood samples were taken from the patients and five periodontally healthy controls, and the serum examined with highly sensitive elisa test kits for interleukin ... | 1996 | 8866317 |
| an investigation into the use of sds-page of cell surface extracts and proteolytic activity to differentiate prevotella nigrescens and prevotella intermedia. | by comparison of the cell surface proteins derived from the outer membrane and fibrils from 14 prevotella intermedia and 19 prevotella nigrescens strains using sds and analysed by sds-page, it was possible to distinguish the two species. a polypeptide of approx. 21 kda distinguished p. intermedia strains, whereas two polypeptides of approx. 18 and 22 kda could be used to identify p. nigrescens strains. four other human oral black pigmented bacterial species (porphyromonas gingivalis, prevotella ... | 1996 | 8869494 |
| evaluation of the long-term efficacy and safety of locally-applied minocycline in adult periodontitis patients. | the objectives of the present study were to establish in a long-term investigation the safety as well as the clinical and microbiological efficacy of scaling and rootplaning combined with local application of 2% minocycline hydrochloride-gel versus placebo-gel in patients with moderate to severe chronic adult periodontitis. this was an 18 months, randomized, double-blind, parallel, comparative study, in which 20 healthy patients with moderate to severe chronic periodontitis participated. at base ... | 1996 | 8877655 |
| the relationship of gingival crevicular fluid short chain carboxylic acid concentration to gingival inflammation. | short-chain carboxylic acids (scca; c < or = 5; e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which accumulate in the gingival crevice, and exhibit significant biological activity, including the ability to alter gene expression. it has been hypothesized that among the activities of sccas are their ability to contribute to gingival inflammation. this concept complements the notion that specific periodontal pathogens are the causative agents of ... | 1996 | 8877660 |
| clonality of porphyromonas gingivalis, prevotella intermedia and prevotella nigrescens isolated from periodontally diseased and healthy sites. | black-pigmented anaerobes have been implicated as major pathogens in the aetiology of adult periodontitis but these organisms are also found in healthy sites. this study aimed to examine the relationship between genotypes of black-pigmented anaerobes and disease status of periodontal sites using restriction endonuclease analysis (rea) and ribotyping. the main black-pigmented species recovered from sites were porphyromonas gingivalis, prevotella intermedia and prevotella nigrescens. each of the 5 ... | 1996 | 8884636 |
| treatment of periodontal disease based on microbiological diagnosis. a 5-year follow-up on individual patterns. | sixteen patients with advanced periodontitis (more than 3 sites with a probing depth > or = 6 mm) were treated with the aim of eliminating actinobacillus actinomyce-temcomitans and porphyromonas gingivalis and reducing prevotella intermedia below 5% of the total viable count. the patients were followed clinically and microbiologically for over 5 years and showed a highly individual pattern with respect to presence of indicator bacteria, type of treatment needed to accomplish treatment goals, cli ... | 1996 | 8884645 |
| compounds from syzygium aromaticum possessing growth inhibitory activity against oral pathogens. | a crude meoh extract of syzygium aromaticum (clove) exhibited preferential growth-inhibitory activity against gram-negative anaerobic periodontal oral pathogens, including porphyromonas gingivalis and prevotella intermedia. by means of bioassay-directed chromatographic fractionation, eight active compounds were isolated from this extract and were identified as 5,7-dihydroxy-2-methylchromone 8-c-beta-d-glucopyranoside, biflorin, kaempferol, rhamnocitrin, myricetin, gallic acid, ellagic acid, and ... | 1996 | 8904847 |
| pcr reaction and dot-blot hybridization to monitor the distribution of oral pathogens within plaque samples of periodontally healthy individuals. | the purpose of this study was to determine the distribution of the putative periodontal pathogens prevotella intermedia, prevotella nigrescens, the three oral capnocytophaga species (c. ochracea, c. sputigena, c. gingivalis), as well as porphyromonas gingivalis and actinobacillus actinomycetemcomitans in plaque samples of periodontally healthy individuals. we chose a newly developed 16s rdna directed polymerase chain reaction (pcr) and a previously described dot-blot hybridization assay to detec ... | 1996 | 8910839 |
| topographic distribution of black-pigmenting anaerobes before and after periodontal treatment by local delivery of tetracycline. | the purpose of this study was to determine the distribution of black-pigmenting gram-negative bacteria in the dentition of 10 adult periodontitis patients before and after treatment by local delivery of tetracycline. the subjects were selected based on a screening for high counts of porphyromonas gingivalis and multiple deep pockets. subgingival microbial samples were taken from the mesial and distal aspect of every tooth (44 to 56 sites per patient) before treatment, and after one and two month ... | 1996 | 8915018 |
| discrepancy between culture and dna probe analysis for the detection of periodontal bacteria. | the purpose of this study was to compare a commercially available dna probe technique with conventional cultural techniques for the detection of actinobacillus actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia in subgingival plaque samples. samples from 20 patients with moderate to severe periodontitis were evaluated at baseline and during a 15 months period of periodontal treatment. paperpoints from 4 periodontal pockets per patient were forwarded to omnigene for dna pro ... | 1996 | 8915026 |
| selling biotechnology in the dental medicine marketplace: the omnigene diagnostics dna probe tests for periodontal pathogens. | omnigene diagnostics, inc. has applied the principles of genetic engineering to develop species-specific dna probe tests for eight periodontal pathogens (porphyromonas gingivalis, prevotella intermedia, actinobacillus actinomycetem-comitans, fusobacterium nucleatum, eikenella corrodens, campylobacter rectus, bacteroides forsythus, and treponema denticola). the test requires minimal effort on the part of the clinician: subgingival plaque samples are collected from the patient and sent through the ... | 1996 | 8931245 |
| degradation of host protease inhibitors and activation of plasminogen by proteolytic enzymes from porphyromonas gingivalis and treponema denticola. | bacterial proteases may participate in the pathogenesis of periodontal diseases through their action on host proteins. in the present study, the ability of selected periodontopathogens, as well as two proteases isolated from porphyromonas gingivalis and treponema denticola, to degrade host protease inhibitors was evaluated. the activation of human plasminogen by the two bacterial proteases was also investigated. proteolytic breakdown of host protease inhibitors (alpha-1-antitrypsin, antichymotry ... | 1996 | 8936322 |
| characteristics of systemic antibody responses of nonhuman primates following active immunization with porphyromonas gingivalis, prevotella intermedia and bacteroides fragilis. | periodontal disease is an infectious disease manifested by the progressive change of a healthy resident commensal microbiota to a pathogenic one characterized by a specific microbiota. thus, the prospect for the use of selected bacteria or their antigens as a vaccine to interfere with the microbial changes and resulting progression of periodontal tissue destruction has been proposed. as a first step in examining the use of bacterial antigens as immunogens in periodontitis, this study characteriz ... | 1996 | 8941758 |
| distribution and genetic analysis of oral prevotella intermedia and prevotella nigrescens. | a total of 344 prevotella intermedia and nigrescens group isolates from 59 subjects were identified by hybridization with nonradioactively labeled species-specific oligonucleotide probes. identification of 20 p. intermedia and 46 p. nigrescens isolates was confirmed by analyzing the electrophoretic mobilities of malate and glutamate dehydrogenase enzymes. a total of 111 isolates (32%) were identified as p. intermedia and 233 isolates (68%) as p. nigrescens. identification performed with oligonuc ... | 1996 | 8941760 |
| characterization of prevotella intermedia and prevotella nigrescens by enzyme production, restriction endonuclease and ribosomal rna gene restriction analyses. | restriction endonuclease analysis, rrna gene restriction analysis (ribotyping), multilocus enzyme electrophoresis and lipase production were investigated for their potential to differentiate isolates belonging to the closely-related species prevotella intermedia and prevotella nigrescens. of 122 strains identified originally as p. intermedia, 52 were assigned to p. intermedia and 68 to p. nigrescens using multilocus enzyme electrophoresis. all 39 p. intermedia and 52 out of 53 p. nigrescens test ... | 1996 | 8941766 |
| risk indicators for periodontal disease in a racially diverse urban population. | a cross-sectional study of 117 subjects from a dental clinic serving a diverse population (i.e., whites, african-americans, native-americans, and asians) was performed to evaluate risk indicators of periodontal disease. gingival crevicular fluid (gcf) and subgingival plaque were taken at the same visit from 4 posterior sites of the most diseased sextant in each subject. age, smoking packyears, beta-glucuronidase (beta g), neutrophil elastase (ne), myeloperoxidase (mpo), fusobacterium nucleatum ( ... | 1996 | 8951624 |
| longitudinal evaluation of the development of periodontal destruction in spouses. | the aim of the present investigation was to study longitudinally the periodontal condition of married couples. the data are derived from a longitudinal study in a young population living in a remote village in indonesia and showing a relatively high prevalence of periodontal destruction. in 23 married couples, clinical measurements were carried out in 1987 and 1994. during the latter examination, a pooled gingival sample was obtained for microbiological evaluation. in 1994, the mean age of the g ... | 1996 | 8951630 |
| microbiological response to mechanical treatment in combination with adjunctive therapy. a review of the literature. | the recognition of the microbial origin and the specificity of periodontal infections has resulted in the development of several adjunctive therapies (antibiotics and/or antiseptics) to scaling and root planing in the treatment of chronic adult periodontitis. this article aims to review the "additional" effect of a subgingival irrigation with chlorhexidine, or a local or systemic application of tetracycline or metronidazole, performed in combination with a single course of scaling and root plani ... | 1996 | 8959563 |
| the adherence of periodontopathogens to periodontal probes. a possible factor in intra-oral transmission? | periodontal probes have previously been shown to harbor several bacterial types or species after probing periodontally diseased pockets. this study aims to identify and quantify periodontopathogens that may adhere to a periodontal probe by culturing techniques. it also examines the probe's roughness on its capability to collect bacteria, comparing merrit-b probes (with deep indentations) with tps probes (with smooth surfaces). from the differential phase contrast microscopy findings it was seen ... | 1996 | 8959565 |
| degradation of lactoferrin by periodontitis-associated bacteria. | the degradation of human lactoferrin by putative periodontopathogenic bacteria was examined. fragments of lactoferrin were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and measured by densitometry. the degradation of lactoferrin was more extensive by porphyromonas gingivalis and capnocytophaga sputigena, slow by capnocytophaga ochracea, actinobacillus actinomycetemcomitans and prevotella intermedia, and very slow or absent by prevotella nigrescens, campylobacter rectus ... | 1996 | 8961558 |
| extracts of periodontopathic microorganisms lack functional superantigenic activity for murine t cells. | products of periodontopathic bacteria exert immunomodulatory effects on various lymphoid cell populations, some of which have been implicated in the pathogenesis of periodontitis. it has recently been suggested that some of these bacterial products may possess superantigenic (sag) activity. sag bind simultaneously to the v beta chain of t cell receptors and to class ii major histocompatibility complex molecules, thereby activating as many as 35% of t cells to proliferate and produce cytokines. i ... | 1996 | 8971649 |
| immune response to anaerobic bacteria in patients with peritonsillar cellulitis and abscess. | the role of four oral organisms (fusobacterium nucleatum. prevotella intermedia, porphyromonas gingivalis, and actinobacillus actinomycetemcomitans) was investigated in 19 children with peritonsillar abscess, and 17 with peritonsillar cellulitis. antibody titers to these organisms were measured by enzyme- linked immunosorbent assay in the patient, as well as in 32 control patients. serum levels in the patients were determined at day 1 and 42-56 days later. significantly higher antibody levels to ... | 1996 | 8973727 |
| polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. | a 16s rrna-based polymerase chain reaction (pcr) detection method was used to determine the prevalence of actinobacillus actinomycetemcomitans, bacteroides forsythus, campylobacter rectus, eikenella corrodens, porphyromonas gingivalis, prevotella intermedia. prevotella nigrescens and treponema denticola in subgingival specimens of 50 advanced periodontitis, 50 adult gingivitis and 50 pediatric gingivitis subjects. the optimal pcr conditions were determined for each study species. agarose gel ele ... | 1996 | 9002880 |
| plaque ph and microflora of dental plaque on sound and carious root surfaces. | given the hypothesis that root caries is the result of acid formation by acidogenic micro-organisms, the present study was performed to relate sucrose-induced ph response of dental plaque on root surfaces to the microbial composition of the overlying plaque. seventeen caries-active elderly chinese with poor oral hygiene and with both sound and carious root surfaces were examined. plaque ph was measured before and up to one hour after a controlled sucrose mouthrinse. plaque samples for microbiolo ... | 1996 | 9003238 |
| immune response to fusobacterium nucleatum and prevotella intermedia in patients with infectious mononucleosis. | the role of four oral flora organisms (fusobacterium nucleatum, prevotella intermedia, porphyromonas gingivalis and actinobacillus actinomycetemcomitans) was investigated in 22 patients with infectious mononucleosis. immunoglobulin-g class antibody titres to these organisms were measured by enzyme-linked immunosorbent assay. serum levels in the patients were determined at day 1 and 42-56 days later. significantly higher antibody levels to f. nucleatum and pr. intermedia were found in the second ... | 1996 | 8642574 |
| repopulation of periodontal pockets by microbial pathogens in the absence of supportive therapy. | this clinical study evaluated the reinfection incidence by actinobacillus actinomycetemcomitans (aa), porphyromonas gingivalis (pg), and prevotella intermedia (pi) in periodontal pockets following scaling and root planing (srp) and intra-pocket irrigation with antimicrobial agents in a patient population who did not receive supportive maintenance therapy. the number of target organisms was determined utilizing dna probes. forty-one (41) inflamed pockets > or = 5 mm with attachment loss and conta ... | 1996 | 8667133 |
| prevotella intermedia and prevotella nigrescens serotypes, ribotypes and binding characteristics. | type strains and 62 clinical isolates of prevotella intermedia and prevotella nigrescens were typed with the use of genomic dna fingerprints and rrna gene probes. the strains were further serotyped with monoclonal antibodies and characterized with sds-page, enzymatic activities, hemolysis and hemagglutination and coaggregation with streptococcus and actinomyces spp. p. intermedia and p. nigrescens were found to have distinct ribotype patterns which correspond to previously defined serotyupes i a ... | 1996 | 8674976 |
| microbiological and serological investigations of oral lesions in papillon-lefèvre syndrome. | microbiological and serological (enzyme linked immunosorbent assay) investigations were carried out, including karyotyping, on two asian children with papillon-lefèvre syndrome. in case 1, a girl aged four years, the most prevalent putative periodontopathogens were eikenella corrodens, fusobacterium nucleatum, porphyromonas gingivalis, prevotella intermedia (deciduous dentition) and bacteroides gracilis, e corrodens and f nucleatum (permanent dentition). in case 2, a boy aged nine years, they we ... | 1996 | 8675741 |
| electrophoresis of whole-cell soluble proteins of microorganisms isolated from bacteremias in endodontic therapy. | we have previously demonstrated that anaerobic bacteria are the microorganisms most frequently isolated from blood following endodontic therapy of teeth with apical periodontitis. phenotypic characterisation of the isolates suggested that the bacteria in the blood originated from the root canal. the present experiment using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) was carried out in an effort to verify these findings, and to further study the microorganisms involved i ... | 1996 | 9021323 |
| anaerobic microorganisms in root canals of human teeth with chronic apical periodontitis detected by indirect immunofluorescence. | aiming to assess the presence of selected anaerobic microorganisms in root canals of human teeth with chronic apical periodontitis. 25 central and lateral upper incisors presenting with radiographic evidence of chronic apical periodontitis were studied. the pulp chamber was opened under aseptic conditions and samples of the root canal content were collected with sterile absorbent paper points, which were placed and dispersed in test tubes containing reduced transport medium rtt. aliquots were dr ... | 1996 | 9028199 |
| tetracycline resistance in prevotella isolates from periodontally diseased patients is due to the tet(q) gene. | tetracycline-resistance in gram-negative periodontal bacteria is often due to the presence of the tet(q) gene. in the present study the polymerase chain reaction (pcr) was used to examine 54 isolates of gram-negative anaerobic rods (prevotella intermedia, prevotella nigrescens and related or bacteroides-like species) for the presence of the tet(q) gene. the isolates were recovered from 42 patients with periodontal disease living in northern europe and north america. an 814 base-pair segment of t ... | 1996 | 9028255 |
| collagen-binding activity of prevotella intermedia measured by a microtitre plate adherence assay. | the ability of prevotella intermedia to bind type i collagen was investigated. a simple method in which bacterial cells were allowed to attach to collagen-coated microtitre plate wells was used to characterize the activity. all strains of p. intermedia tested, as well as those of the closely related species prevotella nigrescens, showed a capacity to attach to the collagen film. exponential-phase cultures of p. intermedia demonstrated a greater binding capacity than older cells. attachment to th ... | 1996 | 8704994 |
| the effect of a single mechanical treatment on the subgingival microflora in patients with hiv-associated gingivitis. | the purpose of the present study was to investigate the effect of a single episode of scaling and root planing on clinical periodontal parameters and on the subgingival microflora in human immunodeficiency virus (hiv)-positive and hiv-negative subjects. 13 subjects participated and were clinically scored at days -7, 7, 30 and 90. 7 subjects were infected with hiv and presented an hiv-associated gingivitis. 6 subjects were hiv-negative with at least 12 teeth affected by conventional gingivitis. n ... | 1996 | 8707976 |
| comparison of the pro-inflammatory cytokine-stimulating activity of the surface-associated proteins of periodontopathic bacteria. | saline extraction of the periodontopathic bacterium, actinobacillus actinomycetemcomitans, releases surface-associated material (sam), a complex mixture of proteins and carbohydrates with potent biological actions on isolated bone and on various mammalian cell populations. in this study, the relative ability of the sam from 5 organisms, implicated in the pathology of periodontal disease, to stimulate human mesenchymal and myelomonocytic cells to synthesize the proinflammatory cytokines - interle ... | 1996 | 8708939 |
| clinical and microbiological observations of early polytetrafluoroethylene membrane exposure in guided bone regeneration. case reports in primates. | premature membrane exposure at one week is described in 3 macaca mulatta monkeys as part of a sequence of experiments on guided bone regeneration. clinical sequelae include redness, edema, and tissue slough. bacteroides fragilis, streptococcus pneumoniae, prevotella intermedia, and staphylococcus intermedius were detected at all prematurely exposed sites. pseudomonas maltophilia, strept, pneumoniae, and p. intermedia were the predominant organisms detected and consisted of more than 10% of the t ... | 1996 | 8708956 |
| the effect of periodontal treatment on periodontal bacteria on the oral mucous membranes. | the aim of this study was to investigate the effect of conventional periodontal treatment on the prevalence of actinobacillus actinomycetemcomitans, porphyromonas gingivalis, and prevotella intermedia on oral mucous membranes in patients with periodontitis. fifteen patients were selected with moderate to severe periodontitis (mean age: 39.8 years, range: 26 to 58). from each patient the 4 deepest sites with bleeding on probing were selected for clinical and microbiological evaluation. at baselin ... | 1996 | 8724705 |
| analytical performance of an immunologic-based periodontal bacterial test for simultaneous detection and differentiation of actinobacillus actinomycetemcomitans, porphyromonas gingivalis, and prevotella intermedia. | the analytical performance of a membrane-based immunoassay for the simultaneous detection and differentiation of actinobacillus actinomycetemcomitans, porphyromonas gingivalis, and prevotella intermedia (including prevotella nigrescens) was investigated. positive reactions were observed for 71 of 71 reference strains and recent oral isolates of a. actinomycetemcomitans, p. gingivalis, and p. intermedia. no cross-reactivity was observed with 39 other common oral and environmental species. the spe ... | 1996 | 8724708 |
| long-term stability of class ii furcation defects treated with barrier membranes. | the present longitudinal study was designed to explore the long-term efficacy of guided tissue regeneration (gtr) in class ii furcation defects and establish the factors that might be responsible for modifying this response. subjects with two or more mandibular molars, one of which had class ii furcation defects, received the hygienic phase of therapy followed by baseline clinical measurements and subgingival plaque sampling. gtr procedure was performed in furcation defect sites using expanded p ... | 1996 | 8724711 |
| antagonistic effect of oral bacteria towards treponema denticola. | this study was designed to isolate oral bacteria exhibiting antagonism towards treponema denticola and to characterize the inhibitory activity. eleven bacterial isolates obtained from subgingival sites and identified as either staphylococcus aureus or streptococcus mutans were found to inhibit the growth of t. denticola. when the activity spectra of these isolates were analyzed, two additional periodontopathogens (porphyromonas gingivalis and prevotella intermedia) were found to be affected, whe ... | 1996 | 8727911 |
| histological and microbiological aspects of ligature-induced periodontitis in beagle dogs. | this study was designed to investigate, using 6 beagle dogs, the levels of selected putative pathogens in healthy sites, in gingivitis sites, and in sites with histologically confirmed attachment loss. levels of attachment loss increased with increasing periods of ligation and reached a maximum of 0.15 mm at 57 days. both histological attachment level and histological pocket depth were found to vary significantly with health/disease status (p < 0.0001). higher numbers of total colony-forming uni ... | 1996 | 8739161 |
| response to periodontal therapy in patients with high or low levels of p. gingivalis, p. intermedia, p. nigrescens and b. forsythus. | in a previous study, subjects receiving either adjunctive tetracycline or augmentin showed, on average, more attachment level gain 10 months post-therapy than subjects receiving either ibuprofen or a placebo, although some subjects in each treatment group showed loss of attachment post-therapy. since differences in treatment response might have been due to differences in the subgingival microbiota, the response to different therapies in subjects with different pre-therapy subgingival microbiotas ... | 1996 | 8739165 |
| utility of 5 major putative periodontal pathogens and selected clinical parameters to predict periodontal breakdown in patients on maintenance care. | the predictive utility of 5 major putative periodontopathic microbial species, "superinfecting" organisms, and several clinical periodontal parameters were assessed relative to periodontitis recurrence over a 12-month period in 78 treated adult patients participating in a 3-month maintenance care program. at baseline, pooled subgingival microbial samples were collected from each patient, and whole-mouth evaluations of probing depth, relative periodontal attachment level, furcation involvement, a ... | 1996 | 8739166 |
| the effect of age on the development of gingivitis. clinical, microbiological and histological findings. | in the present "experimental gingivitis" study, the response of the marginal gingiva to plaque formation was studied in one group of young subjects, 20-25 years of age, and in one group of older subjects, aged 65-80 years. during a 4-week period, all subjects received a series of professional tooth cleaning to establish healthy gingival conditions. a baseline examination (day 0) included assessments of plaque and gingivitis. sites that were examined (the experimental sites) included the mesio-pa ... | 1996 | 8739171 |
| systemic antimicrobial treatment and guided tissue regeneration. clinical and microbiological effects in furcation defects. | the purpose of this investigation was to study the microbiota associated with furcation-involved teeth before and after treatment by the guided tissue regeneration procedure (gtr) with non-resorbable eptfe membranes, and to evaluate the benefit of additional systemic antimicrobial therapy (ornidazole). each of 10 patients contributed 1 pair of bilateral mandibular molars with comparable furcation defects. 5 defects were treated with a membrane and the active drug, 5 were treated without a membra ... | 1996 | 8739172 |
| [the significance of endocrine factors and microorganisms in the development of gingivitis in pregnant women]. | 40-100% of pregnant women suffer from the co-called pregnancy gingivitis. the cause of pregnancy gingivitis is possible multicausal: increased plasma female sex-hormones, alteration in dental plague and perhaps prevotella intermedia in the subgingival plague, together with alteration of immunoresponse. increasing levels of progesterone in the gingiva as well as estrogens due to specific receptors affect vascular permeability and exudation, provoke stasis of microcirculation, increase prostagland ... | 1996 | 9036576 |
| periodontal diseases: microbial factors. | 1996 | 9118283 | |
| microbiology of ligature-induced marginal inflammation around osseointegrated implants and ankylosed teeth in cynomolgus monkeys (macaca fascicularis). | the microbiota associated with ligature-induced marginal inflammation around osseointegrated dental implants, ankylosed teeth, and normal control teeth was investigated in 8 cynomolgus monkeys (macaca fascicularis). submucosal/subgingival plaque was sampled with paper points on the day of literature placement and after 7 weeks. the samples were evaluated by phase-contrast microscopy and by cultivation on enriched non-selective and various solid media. the submucosal/subgingival flora was changed ... | 1996 | 9151583 |
| the influence of abutment surface roughness on plaque accumulation and peri-implant mucositis. | bacterial adhesion to intra-oral, hard surfaces is firmly influenced by the surface roughness to these structures. previous studies showed a remarkable higher subgingival bacterial load on rough surfaces when compared to smooth sites. more recently, the additional effect of a further smoothening of intra-oral hard surfaces on clinical and microbiological parameters was examined in a short-term experiment. the results indicated that a reduction in surface roughness below r(a) = 0.2 microns, the s ... | 1996 | 9151584 |
| the influence of periodontitis on the subgingival flora around implants in partially edentulous patients. | the hypothesis that teeth act as reservoirs of micro-organisms for the colonization of oral implants has recently been stated several times. the present study aimed at examining, in partially edentulous patients with severe periodontitis, whether pockets around teeth and implants harbored a comparable micro-flora. in 6 patients (3 with refractory periodontitis and 3 with advanced chronic adult periodontitis), plaque samples were taken from a deep and shallow pocket around both teeth and implants ... | 1996 | 9151609 |
| a microbiological and clinical study of the safety and efficacy of baking-soda dentifrices. | this article reports the results of a study that examined the clinical and microbiological changes associated with regular use of baking-soda dentifrices. two dentifrice formulations were examined in a 6-month longitudinal study of 101 adult subjects with assessments for plaque, gingival inflammation, and stain at baseline and 3 and 6 months during the active phase of the study, and at 3 months after cessation of product use. one dentifrice contained 52% baking soda and 3% sodium percarbonate (a ... | 1996 | 11524866 |
| elimination of bacteria on different implant surfaces through photosensitization and soft laser. an in vitro study. | microbiologic examinations of implants have shown that certain microorganisms described as periodontal pathogens may have an influence on the development and the progression of peri-implant disease. this experimental study aimed to examine the bactericidal effect of irradiation with a soft laser on bacteria associated with peri-implantitis following exposure to a photosensitizing substance. platelets made of commercially pure titanium, either with a machined surface or with a hydroxyapatite or p ... | 1997 | 9586470 |