Publications

sphingomonas paucimobilis bacteraemia and shock in a patient with rheumatic carditis.	acute rheumatic fever (arf) carditis is treated with steroids, which can cause changes in the cellular immune response, especially decreased cd3 (+) t cells. nosocomial infections due to steroid use for treatment of arf carditis or secondary to the changes in the cellular immune response have not been reported in the literature. sphingomonas paucimobilis is a gram-negative bacillus causing community- and hospital-acquired infections. it has been reported as causing bacteraemia/sepsis, pneumonia ...	2014	25297038
growth-promoting sphingomonas paucimobilis zjsh1 associated with dendrobium officinale through phytohormone production and nitrogen fixation.	growth-promoting sphingomonas paucimobilis zjsh1, associated with dendrobium officinale, a traditional chinese medicinal plant, was characterized. at 90 days post-inoculation, strain zjsh1 significantly promoted the growth of d. officinale seedlings, with increases of stems by 8.6% and fresh weight by 7.5%. interestingly, the polysaccharide content extracted from the inoculated seedlings was 0.6% higher than that of the control. similar growth promotion was observed with the transplants inoculat ...	2014	25142808
a computational study of the dechlorination of β-hexachlorocyclohexane (β-hch) catalyzed by the haloalkane dehalogenase linb.	linb, a haloalkane dehalogenase from sphingomonas paucimobilis ut26, is known to metabolize halohydrocarbons to halide ions and the respective alcohols. its broad substrate specificity allowed its consideration for bioremediation. herein, we have shown its catalytic action toward β-hexachlorocyclohexane (β-hch) - an example of large-size substrates that can be accommodated in its active site. we have analyzed the capability of combined qm/mm schemes to describe in detail the sn2 dechlorination r ...	2014	25102308
fever of unknown origin in a young man.	sphingomonas paucimobilis bacteraemia is a rare infection typically related to nosocomial outbreaks.	2014	24852662
sphingomonas paucimobilis: an unusual cause of meningitis-case report.	sphingomonas paucimobilis is an aerobic gram-negative bacillus. the bacteria can cause infections, which can be devastating and, therefore, the patients need adequate and early antibiotic cover. we are presenting an interesting case of meningitis secondary to an unusual s. paucimobilis infection. this is the second case to our knowledge in the literature on meningitis due to s. paucimobilis. the 31-year-old previously healthy man presented with 2 months' history of weight loss and loss of appeti ...	2014	24201101
posttraumatic sphingomonas paucimobilis endophthalmitis.	a rare case of sphingomonas paucimobilis endophthalmitis secondary to a penetrating globe injury with a retained intraocular foreign body is presented. a 30-year-old man presented with severe pain following a penetrating left eye injury. visual acuity (va) was 6/120. slit-lamp examination revealed perforation of the temporal cornea and iris, hypopyon, and a fibrinous membrane covering the pupil. ultrasonography showed dense vitreous infiltration and an orbital ct-scan confirmed the presence of a ...	2015	26839724
[frequency of colonization and isolated bacteria from the tip of the epidural catheter implanted for postoperative analgesia].	the increased use of epidural analgesia with catheter leads to the need to demonstrate the safety of this method and know the incidence of catheter colonization, inserted postoperatively for epidural analgesia, and the bacteria responsible for this colonization.	2015	25435414
sphingomonas paucimobilis meningitis and ventriculitis in an immunocompromised host.		2015	26671080
combination of glycosphingosomes and liposomal doxorubicin shows increased activity against dimethyl-α-benzanthracene-induced fibrosarcoma in mice.	the present study aimed to assess the antitumor effect of glycosphingolipid-incorporated liposomes (glycosphingosomes) in combination with liposomal doxorubicin (lip-dox) in a mouse model of fibrosarcoma. glycosphingosomes were prepared by incorporating glycosphingolipids isolated from sphingomonas paucimobilis into the liposomes of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, cholesterol, and cardiolipin. tumors were induced by administering dimethyl-α-benzanthracene, and tumor-bearing mice wer ...	2015	26504383
theoretical study of the hydrolysis mechanism of 2-pyrone-4,6-dicarboxylate (pdc) catalyzed by ligi.	2-pyrone-4,6-dicarboxylate lactonase (ligi) is the first identified enzyme from amidohydrolase superfamily that does not require a divalent metal ion for catalytic activity. it catalyzes the reversible hydrolysis of 2-pyrone-4,6-dicarboxylate (pdc) to 4-oxalomesaconate (oma) and 4-carboxy-2-hydroxymuconate (chm) in the degradation of lignin. in this paper, a combined quantum mechanics and molecule mechanics (qm/mm) approach was employed to study the reaction mechanism of ligi from sphingomonas p ...	2015	26188792
sphingomonas zeae sp. nov., isolated from the stem of zea mays.	a yellow-pigmented bacterial isolate (strain jm-791t) obtained from the healthy internal stem tissue of 1-month-old corn (zea mays, cultivar 'sweet belle') grown at the plant breeding unit of the e.v. smith research center in tallassee (elmore county), alabama, usa, was taxonomically characterized. the study employing a polyphasic approach, including 16s rna gene sequence analysis, physiological characterization, estimation of the ubiquinone and polar lipid patterns, and fatty acid composition, ...	2015	25944808
biosynthesis and characterisation of silver nanoparticles using sphingomonas paucimobilis sp. bds1.	sphingomonas is a novel and abundant microbial resource for biodegradation of aromatic compounds. it has great potential in environment protection and industrial production. the use of microorganisms for the synthesis of nanoparticles is in the limelight of modern nanotechnology, since it is cost effective, non-toxic and friendly to the ever-overwhelmed environment. in this paper, the biosynthesis of silver nanoparticles (agnps) using sphingomonas paucimobilis sp. bds1 under ambient conditions w ...	2015	25829169
optimization of culture medium compositions for gellan gum production by a halobacterium sphingomonas paucimobilis.	the effect of culture medium compositions on gellan gum production produced by fermentation with a halobacterium sphingomonas paucimobilis qhzjujw cgmcc2428 was studied. in this work, a fractional factorial design was applied to investigate the main factors that affected gellan gum production by s. paucimobilis qhzjujw cgmcc2428. sucrose was the best carbon source for gellan gum and peptone displayed better inducing effect. central composite design and response surface methodology were adopted t ...	2015	25439950
sphingomonas aeria sp. nov. from indoor air of a pharmaceutical environment.	a proteobacterial strain designated r1-3(t) was isolated from indoor air of a pharmaceutical environment. cells were gram-stain-negative, oxidase- and catalase-positive, aerobic, motile and rod-shaped. strain r1-3(t) grew optimally at ph 7, 30 °c and in 0-2 % nacl on r2a agar. the 16s rrna gene sequence analysis indicated that strain r1-3(t) belongs to the genus sphingomonas, and is closely related to sphingomonas paucimobilis atcc 29837(t) (98.4 % sequence similarity). however, the dna-dna rela ...	2015	25318449
[clinical observations of acute-onset endophthalmitis after clear corneal phacoemulsification].	to evaluate the incidence of acute-onset endophthalmitis after clear corneal phacoemulsification and to report its clinical features, microbiology, and therapeutic efficacy.	2015	26888274
[preliminary analyses on bacterial diversity and resistance in infection-related skin disorders].	to explore the bacterial diversity and resistance in infection-related skin disorders.	2015	26704163
microbiological stability of canned tuna produced in italy and in non-european countries.	the results of a study on the microbiological stability of canned tuna produced by italian companies and similar canned products manufactured in countries outside europe are reported herein. the study involved 38 samples of canned tuna of various brands, of which 14 were produced by companies outside europe and 24 by italian companies. qualitative and quantitative microbiological tests were conducted for the following parameters: bacterial colony counts at 30°c, total coliforms, total enterobact ...	2015	27800383
conjunctival flora of clinically normal and diseased turtles and tortoises.	in captive breed turtles and tortoises conjunctival disease is common. our aim was to investigate the bacterial and fungal flora present in the eyes of healthy and pathological chelonians and to compare findings in turtles with those in tortoises.	2015	25889261
purification and characterization of a fucoidanase (fnase s) from a marine bacterium sphingomonas paucimobilis pf-1.	the search for enzyme activities that efficiently degrade marine polysaccharides is becoming an increasingly important area for both structural analysis and production of lower-molecular weight oligosaccharides. in this study, an endo-acting fucoidanase that degrades miyeokgui fucoidan (mf), a sulfated galactofucan isolated from the sporophyll (called miyeokgui in korean) of undaria pinnatifida, into smaller-sized galactofuco-oligosaccharides (1000-4000 da) was purified from a marine bacterium, ...	2015	26193285
[prevalence of sensitization to fungi in patients with respiratory allergy].	as part of the etiology of respiratory allergy we have genetics, prenatal factors and sensitivity to various airborne allergens, between these fungi are found. relationship has been found between sensitization to fungal in skin tests and allergy pathogenesis and aggravation. there is a few literature in mexico and in the north of the country it is lacking regarding this problem.	2016	27174757
[prevalence of sensitization to allergens in school children with asthma residents from guadalajara metropolitan area].	allergic sensitization is dependent on the geographical and climatic conditions in each region; therefore, identify agents most commonly sensitized children with asthma is important for planning prevention measures.	2016	27174756
[identification of microorganisms related to chronic rhinosinusitis in adult patients with variable common immunodeficiency].	the prevalence of chronic rhinosinusitis in adult patients with common variable immunodeficiency (cvid) is 52%. the patients with cvid show higher incidence of chronic rhinosinusitis, which is an inflammatory disease that affects the lining of one or more paranasal sinuses and nasal cavity.	2016	26943827
draft genome sequence of sphingomonas paucimobilis strain lct-sp1 isolated from the shenzhou x spacecraft of china.	sphingomonas paucimobilis strain lct-sp1 is a glucose-nonfermenting gram-negative, chemoheterotrophic, strictly aerobic bacterium. the major feature of strain lct-sp1, isolated from the chinese spacecraft shenzhou x, together with the genome draft and annotation are described in this paper. the total size of strain lct-sp1 is 4,302,226 bp with 3,864 protein-coding and 50 rna genes. the information gained from its sequence is potentially relevant to the elucidation of microbially mediated corrosi ...	2016	26918090
evaluation of the effectiveness of manual and automated dialyzers reprocessing after multiple reuses.	a cross-sectional study was conducted to evaluate the effectiveness of manual and automated dialyzer reprocessing. dialyzers were filled with fluid thioglycollate medium from blood and dialysate chambers after being reprocessed and chemically sterilized with 0.2% peracetic acid. they were incubated for 14 days at 35°c ± 2°c, and microbiologic analysis was performed. microorganisms were identified in 3 of the 11 samples (27.3%) from the blood chambers: sphingomonas paucimobilis (2/3) and penicill ...	2016	26897699
strategies for decreasing contamination of homemade nasal saline irrigation solutions.	saline nasal irrigations (sni) are an important adjunct in the treatment of rhinosinusitis, and many patients prepare and store these solutions in their homes without an awareness of the potential for contamination. the objectives of this study were to determine if such contamination occurs and the effect of preparation methods on contamination.	2016	26290494
bacterial and fungal contamination risks in human oocyte and embryo cryopreservation: open versus closed vitrification systems.	to study the contamination risk in open and closed vitrification devices for oocyte/embryo cryopreservation by evaluating the contaminants present (bacteria and fungi) in the thaw medium and in liquid nitrogen (ln) storage containers.	2016	27025548
epizootiological characteristics of viable bacteria and fungi in indoor air from porcine, chicken, or bovine husbandry confinement buildings.	microorganisms found in bioaerosols from animal confinement buildings not only foster the risk of spreading diseases among livestock buildings, but also pose health hazards to farm workers and nearby residents. this study identified the various microorganisms present in the air of swine, chicken, and cattle farms with different kinds of ventilation conditions in korea. microbial air samples were collected onto petri dishes with bacterial or fungal growth media using a cascade impactor. endotoxin ...	2016	27456779
non-oral gram-negative facultative rods in chronic periodontitis microbiota.	the subgingival prevalence of gram-negative facultative rods not usually inhabiting or indigenous to the oral cavity (non-oral gnfr), as well as selected periodontal bacterial pathogens, were evaluated by culture in untreated and treated chronic periodontitis patients.	2016	26835659
substrate distortion and the catalytic reaction mechanism of 5-carboxyvanillate decarboxylase.	5-carboxyvanillate decarboxylase (ligw) catalyzes the conversion of 5-carboxyvanillate to vanillate in the biochemical pathway for the degradation of lignin. this enzyme was shown to require mn(2+) for catalytic activity and the kinetic constants for the decarboxylation of 5-carboxyvanillate by the enzymes from sphingomonas paucimobilis syk-6 (kcat = 2.2 s(-1) and kcat/km = 4.0 × 10(4) m(-1) s(-1)) and novosphingobium aromaticivorans (kcat = 27 s(-1) and kcat/km = 1.1 × 10(5) m(-1) s(-1)) were d ...	2016	26714575
sphingomonas paucimobilis bacteremia in an hiv and hepatitis c co-infected patient.	prompt diagnosis and treatment of blood stream infections in an immunocompromised host can result in a decrease in mortality with appropriate antibiotic coverage. signs, symptoms, physical examination, cultures and sensitivity findings must be evaluated and interpreted together to accurately diagnose and manage the problem.	2016	25841882
presence of bacterial virulence gene homologues in the dibenzo-p-dioxins degrading bacterium sphingomonas wittichii.	sphingomonas wittichii, a close relative of the human pathogen sphingomonas paucimobilis, is a microorganism of great interest to the bioremediation community for its ability of biodegradation to a large number of toxic polychlorinated dioxins. in the present study we investigated the presence of different virulence factors and genes in s. wittichii. we utilized phylogenetic, comparative genomics and bioinformatics analysis to investigate the potentiality of s. wittichii as a potential virulent ...	2016	28197061
post-clear corneal phacoemulsification endophthalmitis: profile and management outcomes at a tertiary eye care center in western india.	infectious endophthalmitis is a serious sight threatening intraocular inflammation that results from exogenous or endogenous spread of organisms into the eye.a retrospective case series to study the profile of endophthalmitis following clear corneal phacoemulsification in western india between years 2008 and 2014 was held in the national institute of ophthalmology, pune, india. cases of endophthalmitis post-clear corneal phacoemulsification were reviewed pertaining to demography, clinical histor ...	2016	27896783
degradation of lignin β-aryl ether units in arabidopsis thaliana expressing ligd, ligf and ligg from sphingomonas paucimobilis syk-6.	lignin is a major polymer in the secondary plant cell wall and composed of hydrophobic interlinked hydroxyphenylpropanoid units. the presence of lignin hampers conversion of plant biomass into biofuels; plants with modified lignin are therefore being investigated for increased digestibility. the bacterium sphingomonas paucimobilis produces lignin-degrading enzymes including ligd, ligf and ligg involved in cleaving the most abundant lignin interunit linkage, the β-aryl ether bond. in this study, ...	2016	27775869
successful return to peritoneal dialysis after a case of relapsing sphingomonas paucimobilis peritonitis .	sphingomonas paucimobilis is an uncommon source of peritonitis in patients undergoing peritoneal dialysis (pd). although only a small number of cases have been reported, treatment failure rate is extremely high, with removal of the peritoneal dialysis catheter noted in ~ 50% of reported cases. the potential damage to the peritoneal membrane from peritonitis with this organism and the ability to return to pd after infection is unknown. we report a unique case in which a patient was able to succes ...	2016	27730806
recurrent complicated urinary tract infection due to rare pathogen sphingomonas paucimobilis: contamination or real deal?	sphingomonas paucimobilis is an aerobic, oxidase-positive, yellow-pigmented, non-fermentative, gram-negative opportunistic pathogen that rarely causes infections in humans. it is commonly found in nosocomial environments and, despite its low clinical virulence, it can be responsible for several different infections especially among patients with underlying disease. here we describe a clinical case of a 46-year-old male paraplegic patient with a history of neurogenic bladder due to insulin-depend ...	2016	27668907
oral ulcer by sphingomonas paucimobilis: first report.	the first case of an oral infection caused by sphingomonas paucimobilis is reported. a 73-year-old man presented with a gingival ulcer with bone exposure affecting the attached gingiva in the anterior maxillary region. he reported pain during chewing and the presence of fever. since the first case of s. paucimobilis infection was reported in 1977, involving a leg ulcer, the number of reports related to this organism has been increasing, indicating that the bacterium should be considered an emerg ...	2016	27515851
modulation of dendritic-epithelial cell responses against sphingomonas paucimobilis by dietary fibers.	non-fermenting gram-negative bacilli, such as sphingomonas paucimobilis (s.paucimobilis), are among the most widespread causes of nosocomial infections. up to now, no definitive guidelines exist for antimicrobial therapy for s. paucimobilis infections. as we have shown that some dietary fibers exhibit pronounced immune-regulatory properties, we hypothesized that specific immune active dietary fibers might modulate the responses against s. paucimobilis. we studied the immunomodulatory effects of ...	2016	27452116
a tetrahydrofolate-dependent methyltransferase catalyzing the demethylation of dicamba in sphingomonas sp. strain ndbn-20.	sphingomonas sp. strain ndbn-20 degrades and utilizes the herbicide dicamba as its sole carbon and energy source. in the present study, a tetrahydrofolate (thf)-dependent dicamba methyltransferase gene, dmt, was cloned from the strain, and three other genes, metf, dhc, and puru, which are involved in thf metabolism, were found to be located downstream of dmt a transcriptional study revealed that the four genes constituted one transcriptional unit that was constitutively transcribed. lysates of c ...	2016	27422839
a lethal case of sphingomonas paucimobilis bacteremia in an immunocompromised patient.	sphingomonas paucimobilis is a yellow-pigmented, glucose nonfermenting, aerobic, gram negative bacillus of low pathogenicity. this organism was found in the implantation of indwelling catheters, sterile intravenous fluid, or contaminated hospital environment such as tap and distilled water, nebulizer, ventilator, and hemodialysis device. a 55-year-old female was hospitalized for diabetic foot ulcer in the presence of multiple comorbidities: diabetes mellitus, colonic tuberculosis, end-stage rena ...	2016	27088020
kinetics of bisphenol a degradation by sphingomonas paucimobilis fj-4.	a chemostat was operated to characterize degradation of bisphenol a by sphingomonas paucimobilis fj-4. the chemostat at 30°c was fed with a medium containing 150 mg l(-1) of bpa as the sole carbon and energy source. at the short cell retention time of 8 h, the bacterial cells were washed out from the chemostat. at long cell retention times of 12, 16, 24, and 48 h, steady-states of the bacterial growth on bpa degradation were achieved after a lag time of 16-57 h. a mathematical model was applied ...	2016	27038671
sphingomonas paucimobilis causing pacemaker pocket infection in a pediatric patient with a hemangioma.		2016	26781221
frequency of colonization and isolated bacteria from the tip of epidural catheter implanted for postoperative analgesia.	the increased use of epidural analgesia with catheter leads to the need to demonstrate the safety of this method and know the incidence of catheter colonization, inserted postoperatively for epidural analgesia, and the bacteria responsible for this colonization.	2016	25925032
structure of aryl o-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism.	some strains of soil and marine bacteria have evolved intricate metabolic pathways for using environmentally derived aromatics as a carbon source. many of these metabolic pathways go through intermediates such as vanillate, 3-o-methylgallate, and syringate. demethylation of these compounds is essential for downstream aryl modification, ring opening, and subsequent assimilation of these compounds into the tricarboxylic acid (tca) cycle, and, correspondingly, there are a variety of associated aryl ...	2017	28373573
improving water quality in a dialysis unit using root cause analysis.	water quality levels from hemodialysis (hd) and reverse osmosis (ro) machines in dialysis units must meet standards set by the american association of medical instrumentation. researchers used a root cause analysis (rca) approach to identify and address factors affecting water quality in the hd and portable ro machines at our institution.	2017	28302433
the autophagy machinery restrains inkt cell activation through cd1d1 internalization.	invariant natural killer t (inkt) cells are innate t cells with powerful immune regulatory functions that recognize glycolipid antigens presented by the cd1d protein. while inkt cell-activating glycolipids are currently being explored for their efficacy to improve immunotherapy against infectious diseases and cancer, little is known about the mechanisms that control cd1d antigen presentation and inkt cell activation in vivo. cd1d molecules survey endocytic pathways to bind lipid antigens in mhc ...	2017	28296542
sphingomonas paucimobilis peritonitis: a case report and review of the literature.	sphingomonas paucimobilis, a yellow-pigmented, aerobic, glucose non-fermenting, gram-negative bacillus, is a rare cause of human infection normally associated with immunocompromised hosts. it has been associated with a few cases of continuous ambulatory peritoneal dialysis (pd) and is notorious for its resistance to the commonly used antibiotics. in half of the cases reported so far, the peritonitis was refractory to treatment, necessitating pd catheter removal. we report a case of sphingomonas ...	2017	26022030
[spontaneous bacterial peritonitis due to sphingomonas paucimobilis in a cirrhotic patient].		2017	26620600
sphingomonas paucimobilis septicemia in a neonate: a rare case report.	sphingomonas paucimobilis , a yellow-pigmented, aerobic, glucose nonfermenting, gram-negative bacilli is a rare cause of human infection. it was first discovered as an infective agent in humans in 1977 and named pseudomonas paucimobilis. it was renamed as s. paucimobilis in 1990 in accordance with phylogenetic data. s. paucimobilis is an aerobic bacterium found in soil and water; it is a rare cause of healthcare associated infections. s. paucimobilis can cause infections in healthy as well as im ...	2017	26960657
risk of infection transmission in curvilinear array echoendoscopes: results of a prospective reprocessing and culture registry.	the complex design of the elevator mechanism in duodenoscopes has been recognized as a challenge for disinfection and recently implicated as a potential source of persistent bacterial contamination. curvilinear array (cla) echoendoscopes also have an elevator mechanism; however, there are no recommendations or data regarding the risk of persistent bacterial contamination of echoendoscopes. here we hoped to determine the yield of microbial growth with routine bacterial surveillance cultures of re ...	2017	27478029
identification of bacteria in blood cultures from clinically ill captive antillean manatees (trichechus manatus manatus).	between september 2001 and march 2013, 62 bacterial cultures (37 aerobic and 25 anaerobic) were performed on 37 blood samples from 23 antillean manatees ( trichechus manatus manatus) that were kept in captivity at the brazilian national center for research and conservation of aquatic mammals (cma) in pernambuco (cma-pe) and alagoas (cma-al), brazil. all of the animals sampled exhibited clinical signs at the time of sampling including abscesses (n = 8), debilitation and anorexia (n = 22), and pro ...	2017	28363079
enantioselective resolution of (r,s)-carvedilol to (s)-(-)-carvedilol by biocatalysts.	among the microorganisms employed in the study, aspergillus niger (gufcc5443), escherichia coli (atcc9637), streptomyces halstedii (ckm-2), pseudomonas putida (ncib9494), cunninghamella elegans (ncim689) and sphingomonas paucimobilis (nctc11030) were capable for the enantioselective conversion of racemic carvedilol. immobilization technique enhanced the enantioselectivity of microorganisms and thus increased the enantiomeric purity of the drug. excellent enantiomeric ratios (e) were found in rea ...	2017	28064425
coexistence of free-living amoebae and bacteria in selected south african hospital water distribution systems.	pathogenic free-living amoebae (fla), such as naegleria fowleri, balamuthia mandrillaris and acanthamoeba species isolated from aquatic environments have been implicated in central nervous system, eye and skin human infections. they also allow the survival, growth and transmission of bacteria such as legionella, mycobacteria and vibrio species in water systems. the purpose of this study was to investigate the co-occurrence of potentially pathogenic fla and their associated bacteria in hospital w ...	2017	27730363