Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| on some genetic aspects of phage lambda resistance in e. coli k12. | most mutations rendering e. coli k12 resistant to phage lambda, map in two genetic regions mala and malb.-the malb region contains a gene lamb specifically involved in the lambda receptor synthesis. twenty-one independent lamb mutations studied by complementation belonged to a single cistron. this makes it very likely that lamb is monocistronic. among the lamb mutants some are still sensitive to a host range mutant of phage lambda. mutations mapping in a proximal gene essential for maltose metab ... | 1972 | 4558324 |
| maturation and recombination of bacteriophage lambda dna molecules in the absence of dna duplication. | 1972 | 4559112 | |
| a reanalysis of red-mediated reciprocal recombination in bacteriophage lambda. | 1972 | 4559691 | |
| mechanism of transcription in the n operon of bacteriophage lambda. | 1972 | 4560678 | |
| plasmid-controlled variation in the content of methylated bases in bacteriophage lambda deoxyribonucleic acid. | the n(6)-methyladenine (meade) and 5-methylcytosine (mec) contents in deoxyribonucleic acid (dna) of bacteriophage lambda has been analyzed as a function of host specificity. the following facts have emerged: (i) lambda grown on strains harboring the p1 prophage contain ca. 70 more meade residues/dna molecule than lambda grown either in the p1-sensitive parent, or in a p1 immune-defective lysogen which does not confer p1 modification; (ii) lambda grown on strains harboring the n-3 drug-resistanc ... | 1972 | 4561202 |
| degradation of bacteriophage lambda deoxyribonucleic acid after restriction by escherichia coli k-12. | wild-type bacteria which restrict the deoxyribonucleic acid (dna) of infecting phage when the phage do not carry the proper host modification rapidly degrade that restricted dna to acid-soluble products. the purified restriction enzyme acts as an endonuclease in vitro to cleave restrictable dna and does not further degrade the dna fragments produced. we have examined mutants of escherichia coli k-12 which lack various nucleases in order to determine which nucleases are involved in the rapid acid ... | 1972 | 4562392 |
| interaction of the recombination pathways of bacteriophage lambda and host escherichia coli: effects on lambda recombination. | 1972 | 4563260 | |
| interaction of the recombination pathways of bacteriophage lambda and its host escherichia coli k12: effects on exonuclease v activity. | 1972 | 4563261 | |
| behavior of coliphage lambda in shigella flexneri 2a. | the insensitivity of wild-type shigella flexneri 2a to coliphage lambda is a consequence of its native genetic defect in the mala gene cluster. the "smooth" s. flexneri 2a lipopolysaccharide layer affects the efficient adsorption of lambda. derivatives, capable of serving as functional hosts for lambda, were obtained by repairing the mala lesion, enabling the expression of the malb-lambdarcp region of s. flexneri. introduction of a mutation into s. flexneri causing a "rough" lipopolysaccharide c ... | 1972 | 4563593 |
| formation of hybrids between coliphage lambda and salmonella phage p22 with a salmonella typhimurium hybrid sensitive to these phages. | an unusual salmonella typhimurium hybrid with sensitivity to coliphage lambda and salmonella phage p22 has been recovered from matings between an escherichia coli k-12 hfr donor and an s. typhimurium recipient. the hybrid is an excellent host for achieving genetic recombination between lambda and p22. two broad classes of hybrid phages were isolated. the lambda-p22 hybrid class, which has the protein coat of lambda, contains at least the c region of p22. the p22-lambda hybrid class has the prote ... | 1972 | 4564201 |
| precursor and product in bacteriophage lambda recombination. | analyses of the time of recombination in bacteria infected with phage lambda and in spheroplasts infected with purified phage lambda dna indicate a preponderance of recombination occurring before replication ("early recombination") after infection with tandem dimers formed in vitro compared to linear monomer dna and phage infections. among the early recombinants is a large fraction of cells that produces one recombinant type exclusively. two suggestions are discussed-that a dimer-like molecule i ... | 1972 | 4564207 |
| fine-structure deletion map of the escherichia coli l-arabinose operon. | a fine-structure deletion map of the l-arabinose operon of e. coli was constructed by mapping deletion endpoints against point mutations. of 350 independent deletions with average endpoint separation of ten nucleotides, 51 ended in the control region between the c and b genes, and the rest ended in the structural genes a, b, c, and d. if deletion endpoints are randomly distributed, the c and b genes are separated by about 510 nucleotides. deletion endpoints and locations of point mutations in fa ... | 1972 | 4564212 |
| methylation pattern of lambda deoxyribonucleic acid. | deoxyribonucleic acid (dna) extracted from phage lambda grown on escherichia coli k-12 strain w4032 had 113 +/- 10 5-methylcytosine residues and 215 +/- 20 6-methyl adenine residues per genome, as determined by three independent methods. these methylated nucleotides were distributed equally among the two strands of lambda dna. shearing of double-stranded dna to half-length fragments revealed a slight deficiency of 5-methyl cytosine in the 55% guanine plus cytosine half. shearing the dna to fragm ... | 1972 | 4564587 |
| purification and properties of d protein: a transcription factor of escherichia coli. | d factor is protein that stimulates dna transcription in vitro by rna polymerase. for dna from bacteriophage lambda, we present evidence that d protein interacts with dna to increase the frequency and improve the specificity of initiation by rna polymerase. | 1972 | 4566455 |
| gene expression by constitutive mutants of coliphage lambda. | 1972 | 5015426 | |
| isolation and structure of phage lambda head-mutant dna. | 1972 | 5022188 | |
| head assembly steps controlled by genes f and w in bacteriophage lambda. | 1972 | 5022189 | |
| tandem genetic duplications in a derivative of phage lambda. ii. evidence for structure and location of endpoints. | 1972 | 5023665 | |
| relationship between the n function of bacteriophage lambda and host rna polymerase. | 1972 | 5040359 | |
| chemical synthesis of the "sticky end" of lambda phage dna r-strand. | 1972 | 5043189 | |
| repression by the ci protein of phage lambda: in vitro inhibition of rna synthesis. | 1972 | 5045305 | |
| repression by the ci protein of phage lambda: interaction with rna polymerase. | 1972 | 5045306 | |
| lambda phage mutants insensitive to temperature-sensitive repressor. 3. effects of virl, virr or virc mutation on the gene expression. | 1972 | 5046962 | |
| isolation and characterization of deletions in bacteriophage lambda residing as prophage in e. coli k 12. | 1972 | 5057547 | |
| dna-replication of spi - mutants of bacteriophage lambda in recombination-deficient bacteria. | 1972 | 5057549 | |
| the net hydration of phage lambda. | 1972 | 5078393 | |
| new banding species, with densities of phage-ghost clusters, produced from lambda phage particles on storage. | 1972 | 5078394 | |
| isolation and properties of rex - mutants of bacteriophage lambda. | twenty-five rex(-) mutants of phage lambda have been isolated. three of the mutants, including one amber mutant, map at three distinct sites within the rex region of the lambda genetic map. the existence of the amber mutant provides further evidence that rex and ci are distinct genes, since it seems to be identical to wild-type lambda in its ability to establish or maintain lysogeny. | 1972 | 5084465 |
| polar mutations in lac, gal and phage lambda consist of a few is-dna sequences inserted with either orientation. | 1972 | 4567156 | |
| increased stability and reproducibility of escherichia coli spheroplasts in the transfection assay of phage lambda dna with polyethylene glycol instead of sucrose. | 1972 | 4622293 | |
| pleiotropic properties and genetic organization of the tola,b locus of escherichia coli k-12. | colicin-tolerant mutants of escherichia coli k-12, which map near gal at 17 min (tola, b mutants), have been isolated and characterized. these mutants exhibited a very broad spectrum of phenotypic changes consistent with the interpretation that they are cell surface mutants. in addition to being colicintolerant and sensitive to deoxycholate and ethylenediaminetetraacetic acid, tola, b mutants are sensitive to vancomycin, bacitracin, and dodecyl sulfate. the tola, b mutants from most strains also ... | 1972 | 4627928 |
| influence of proflavine on the cyclization and aggregation of phage lambda dna. | 1972 | 4660954 | |
| factors influencing competence of escherichia coli for lambda-phage deoxyribonucleic acid infection. | 1972 | 4569211 | |
| host specificity of salmonella typhimurium deoxyribonucleic acid restriction and modification. | the restriction and modification genes of salmonella typhimurium which lie near the thr locus were transferred to a restrictionless mutant of escherichia coli. these genes were found to be allelic to the e. coli k, b, and a restriction and modification genes. e. coli recombinants with the restriction and modification host specificity of s. typhimurium restricted phage lambda that had been modified by each of the seven known host specificities of e. coli at efficiency of plating levels of about 1 ... | 1973 | 4570605 |
| bacterial cell division regulation: lysogenization of conditional cell division lon - mutants of escherichia coli by bacteriophage. | the lon(-) mutants of escherichia coli grow apparently normally except that, after temporary periods of inhibition of deoxyribonucleic acid synthesis, septum formation is specifically inhibited. under these conditions, long, multinucleate, nonseptate filaments result. the lon(-) mutation also creates a defect such that wild-type bacteriophage lambda fails to lysogenize lon(-) mutants efficiently and consequently forms clear plaques on a lon(-) host. two lines of evidence suggest that this failur ... | 1973 | 4570782 |
| characterization of the mrna transcribed from the head and tail genes of phage lambda chromosome. | 1973 | 4573271 | |
| lysogenization by bacteriophage lambda. i. multiple infection and the lysogenic response. | 1973 | 4573866 | |
| e. coli mutants produced by the insertion of bacteriophage lambda dna. | 1973 | 4576121 | |
| genetic recombination induced by dna cross-links in repressed phage lambda. | 1973 | 4576122 | |
| excretion of enterochelin by exba and exbb mutants of escherichia coli. | escherichia coli mutants that are insensitive to colicins b and i hyperproduce and excrete the iron chelator enterochelin, which is an inhibitor of these colicins. these mutants are classified as exba and exbb. the exba mutants are chromium sensitive and require iron for growth, and the mutations are located in the tonb region at min 25 of the e. coli chromosome. tonb mutants in which the genome of phage lambda is inserted into the bacterial chromosome within the tonb gene also exhibit enteroche ... | 1973 | 4576403 |
| comparison of the resa1 and pola1 mutations in isogenic strains of escherichia coli k-12. | strains carrying either the pola1 or resa1 mutation are deficient in dna polymerase i, and the pola1 and resa1 mutations do not complement in merozygotes. the effect of these mutations in otherwise identical genetic backgrounds was studied: after ultraviolet irradiation both strains degrade their dna more rapidly and more extensively than the wild-type strains. however, after x-ray irradiation the resa1 strain shows little dna breakdown and repairs its single-strand breaks. in contrast, the pola ... | 1973 | 4576410 |
| prophage induction by high temperature in thermosensitive dna mutants lysogenic for bacteriophage lambda. | high-temperature treatment of thermosensitive dna mutants lysogenic for phage lambda leads to prophage induction and release of phage (at the permissive temperature) in elongation-defective mutants of the genotypes dnab, dnae, and dnag. in initiation-defective mutants no prophage induction occurs at 42 c in mutants of the genotype dnaa, whereas with a dnac mutant as well as with strain hfrh 252 (map position not yet known) phages are released at 42 c. dna degradation at the replication fork at 4 ... | 1973 | 4576518 |
| [bacteriophage lambda dna-dependent synthesis of endolysin in a membranous cell-free system of e. coli]. | 1973 | 4576624 | |
| intermediates in the maturation of bacteriophage lambda dna. | 1973 | 4576745 | |
| a sedimentation analysis of dna found in escherichia coli infected with phage lambda mutants. | 1973 | 4576746 | |
| replicator mutants of bacteriophage lambda: characterization of two subclasses. | 1973 | 4576747 | |
| bacteriophage lambda dna synthesized by mutants in gene n. | 1973 | 4576748 | |
| ultraviolet reactivation of lambda phage: assay of infectivity of dna molecules by spheroplast transfection. | 1973 | 4577040 | |
| properties of a mutant of escherichia coli defective in bacteriophage lambda head formation (groe). i. initial characterization. | 1973 | 4578098 | |
| properties of a mutant of escherichia coli defective in bacteriophage lambda head formation (groe). ii. the propagation of phage lambda. | 1973 | 4578099 | |
| host participation in bacteriophage lambda head assembly. | 1973 | 4578100 | |
| isolation of a ribonuclease associated with the formation of phage lambda-ci. | 1973 | 4578800 | |
| structural change of dna during lambda-phage lysogenization and induction. | 1973 | 4579423 | |
| role of dna topology in transcription of coliphage lambda in vivo. ii. dna topology protects the template from exonuclease attack. | 1973 | 4579547 | |
| incisions in ultraviolet irradiated circular bacteriophage lambda dna molecules in excision proficient and deficient lysogens of e. coli. | 1973 | 4579985 | |
| the role of c3 product and anti-immunity in zygotic induction of bacteriophage lambda. | 1973 | 4580270 | |
| replication of bacteriophage lambda dna dependent on the function of host and viral genes. i. interaction of red, gam and rec. | 1973 | 4580674 | |
| an analysis of the processes of infection and induction of e. coli mutant hfl-1 by bacteriophage lambda. | 1973 | 4580731 | |
| postirradiation fate of bacteriophage lambda dna in the host cell. | 1973 | 4580735 | |
| physical studies of rna involvement in bacteriophage lambda dna replication and prophage excision. | 1973 | 4580911 | |
| requirement for transcription in the neighborhood of the phage attachment region for lysogenization of escherichia coli by bacteriophage lambda. | 1973 | 4580912 | |
| distinct effects of diamines, polyamines, and magnesium ions on the stability of lambda phage heads. | 1973 | 4581784 | |
| repair of gamma-ray-induced damage in bacteriophage lambda. | 1973 | 4582608 | |
| influence of thymine starvation on the integrity of episomal and chromosomal deoxyribonucleic acids in escherichia coli cr34 (lambda ind-). | the effect of thymine deprivation on the integrity of phage lambda, sex factor, and chromosomal deoxyribonucleic acid (dna) in escherichia coli cr34 (lambda ind(-)) was examined by sedimenting cell lysates through alkaline sucrose gradients. both sex factor and chromosomal dnas showed evidence of being degraded during the starvation period. in contrast, no loss of closed circular lambda dna was observed. | 1973 | 4583234 |
| a new effect of the rex gene of phage lambda: premature lysis after infection by phage t1. | 1973 | 4583305 | |
| genetic characterization of a prm- mutant of bacteriophage lambda. | 1973 | 4583306 | |
| loss of an essential function of escherichia coli by deletions in the thya region. | in an attempt to obtain deletions in the thya gene, an abnormal lysogen of lambda having the prophage inserted between the thya and lysa genes was induced, and the surviving cured cells were examined for thy(-) and lys(-) mutants. in nearly 10,000 cured cells, 184 lys(-) but no thy(-) mutants were found. at the same time, the induced lambda phage contained an approximately equivalent number of lambdathya(+) and lambdalysa(+) transducing particles. by contrast, in a strain with the genotype f' th ... | 1973 | 4584799 |
| infection of escherichia coli envelope-membrane complex with lambda phage: adsorption and penetration. | 1973 | 4585981 | |
| fate of bacteriophage lambda in non-immune germ-free mice. | 1973 | 4586796 | |
| role of the cro gene in bacteriophage lambda development. | 1973 | 4587402 | |
| prophage lambda at unusual chromosomal locations. ii. mutations induced by bacteriophage lambda in escherichia coli k12. | 1973 | 4587404 | |
| regulation of bacteriophage lambda development. | 1973 | 4593172 | |
| control of gene expression in bacteriophage lambda. | 1973 | 4593306 | |
| evidence that pretreatment of escherichia coli cells with n-methyl-n'-nitro-n-nitrosoguanidine enhances mutability of subsequently infecting phage lambda. | 1973 | 4593995 | |
| on maturation of the bacteriophage lambda chromosome. | 1973 | 4594001 | |
| [study of the characteristics of lambda phage dna transfection in e. coli cells treated with cacl2. the role of ca2+ ions at various stages of phage transfection]. | 1973 | 4594845 | |
| expression of the trp operon in phi80trp transducing phages. orientation of transcription and an artificial high-efficiency promotor in phage lambda h +phi80 pt5-2ab. | 1973 | 4686211 | |
| two repressors in bacteriophage lambda. | 1973 | 4686213 | |
| repair mechanisms involved in prophage reactivation and uv reactivation of uv-irradiated phage lambda. | 1973 | 4688367 | |
| lack of specific inhibition of vaccinia plaque formation by bacteriophage lambda products. | unsuccessful efforts to confirm the production of a specific antiviral agent (phagicin) by bacteriophage lambda are reported. | 1973 | 4716545 |
| repressor and rex product of coliphage lambda: lack of collaboration and joint controls. | 1973 | 4725965 | |
| effect of the n-bypass mutations nin and byp on the rightward transcription in coliphage lambda. | 1973 | 4746875 | |
| nucleotide sequence analysis of dna. xi. the 3' terminal sequences of bacteriophage lambda and phi 80 dna. | 1973 | 4753202 | |
| a minor pathway leading to plaque-forming particles in bacteriophage lambda. studies on the function of gene d. | 1973 | 4758067 | |
| mutations in the right operator of bacteriophage lambda: evidence for operator-promoter interpenetration. | 1973 | 4758068 | |
| mutations in the right operator of bacteriophage lambda: physiological effects. | 1973 | 4758069 | |
| characterization of polypeptides made in vitro from bacteriophage lambda dna. | 1973 | 4762922 | |
| restriction of bacteriophage lambda by escherichia coli k. | 1973 | 4767461 | |
| deletion mutants of bacteriophage lambda. iv. high frequency int-promoted recombination. | 1973 | 4772128 | |
| attachment site mutants of bacteriophage lambda. | 1973 | 4778806 | |
| gene n regulator function of phage lambda immun21: evidence that a site of n action differs from a site of n recognition. | 1973 | 4778807 | |
| control of short leftward transcripts from the immunity and ori regions in induced coliphage lambda. | 1973 | 4784811 | |
| positive and negative control of transcription in bacteriophage lambda. | 1973 | 4807323 | |
| isolation of a new rna polymerase-binding protein from sporulating bacillus subtilis. | rna polymerase was precipitated from extracts of radioactively labeled vegetative and sporulating bacillus subtilis with antiserum prepared against vegetative core polymerase. the precipitates were solubilized and analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. antiserum added to an extract of vegetative b. subtilis precipitated only the known subunits of core rna polymerase, but antiserum added to an extract of sporulating cells precipitated a new polypeptide of 70,000 da ... | 1973 | 4631355 |
| repressor, operators, and promoters in bacteriophage lambda. | 1973 | 4618262 | |
| transfection of escherichia coli spheroplasts. ii. relative infectivity of native, denatured, and renatured lambda, t7, t5, t4, and p22 bacteriophage dnas. | the change of infectivity of phage dnas after heat and alkali denaturation (and renaturation) was measured. t7 phage dna infectivity increased 4- to 20-fold after denaturation and decreased to the native level after renaturation. both the heavy and the light single strand of t7 phage dna were about five times as infective as native t7 dna. t4 and p22 phage dna infectivity increased 4- to 20-fold after denaturation and increased another 10- to 20-fold after renaturation. these data, combined with ... | 1973 | 4591046 |
| genetic analysis of bacteriophage lambda strains which transduce the genes for leucine biosynthesis. | 1973 | 4591366 | |
| repair mechanisms involved in the recovery of phage lambda from ultraviolet damage. | 1973 | 4618990 | |
| interference with the expression of the n gene function of phage lambda in a mutant of escherichia coli. | 1973 | 4567743 | |
| an endonuclease induced by bacteriophage lambda. | 1973 | 4567785 |