Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| studies on the mechanism of recovery in pneumococcal pneumonia : i. the action of type specific antibody upon the pulmonary lesion of experimental pneumonia. | a uniformly fatal lobar pneumonia was produced in white rats by inoculation of the left main bronchus with virulent type i pneumococci suspended in mucin. all of the animals succumbed in less than 5 days, half of them dying within 48 hours. in only 5 of 40 rats was the lesion confined to the left lung, and all but one developed pleurisy, pericarditis, or both. all had bacteriemia at the time of death. the pathogenesis of the pulmonary lesion was studied by examining the lungs of 35 rats killed a ... | 1941 | 19871073 |
| studies on photo-oxidation of antigen and antibodies. | 1. quantitative precipitin studies indicate that progressive photo-oxidation progressively destroys the antigenic function of egg albumin. 2. quantitative precipitin reactions of antisera (anti-egg albumin rabbit serum and antipneumococcus type i horse serum) demonstrate that progressive photo-oxidation causes progressive lowering of the potency of the sera. 3. quantitative precipitin reactions of the photo-oxidized globulin gamma fraction of anti-egg albumin rabbit serum and of felton solution ... | 1941 | 19871074 |
| quantitative experiments with antibodies to specific precipitates. ii. | 1. antisera have been produced in chickens with specific precipitates from type ii pneumococcus horse and rabbit antisera. 2. specific precipitates from anti-types i and ii pneumococcus horse sera removed the same amount of antibody from the chicken anti-horse specific precipitate serum. specific precipitates from horse antisera to diphtheria toxin and to crystalline egg albumin removed about one-half of the antibody. 3. specific precipitates from anti-egg albumin, antipneumococcus c substance, ... | 1941 | 19871078 |
| hereditary transmission of the western type of equine encephalomyelitis virus in the wood tick, dermacentor andersoni stiles. | the western type of equine encephalomyelitis virus can be passed as an hereditary infection in a tick of the family ixodidae, dermacentor andersoni stiles. under experimental conditions, this virus has been carried in this tick for two successive generations, possibly for a third, passing certainly once, and possibly twice, from the female through the eggs to the larvae. the virus-carrying larval, nymphal, and adult stages of this tick, furthermore, are capable of infecting susceptible hosts whe ... | 1941 | 19871094 |
| influence of age on susceptibility and on immune response of mice to eastern equine encephalomyelitis virus. | the experiments described in this paper were carried out with the rockefeller institute strain of albino mice and with the eastern strain of the virus of equine encephalomyelitis. 1. the observation was confirmed that with increasing age of mice there occurred a decrease in susceptibility to intraperitoneal injection of active virus; also, the length of incubation period of those which succumbed increased with age. 2. the mice of various age groups which survived an intraperitoneal injection of ... | 1941 | 19871121 |
| the complement fixation test in the diagnosis of virus infections of the central nervous system. | a specific complement fixation test can be obtained in various central nervous system virus infections by using as antigens emulsions of infected brain tissue, freezing and thawing the brain emulsion, and then centrifuging it in an angle head centrifuge at 3500 r.p.m. for 1 hour. the method has proved reliable in the case of rabies, st. louis encephalitis, japanese b encephalitis, lymphocytic choriomeningitis, eastern equine encephalomyelitis, western equine encephalomyelitis, louping ill, and s ... | 1941 | 19871144 |
| the influence of proteins on the reactivation of yeast invertase. | 1. acid-inactivated yeast invertase could not be regenerated in the presence of the proteolytic enzymes trypsin, pepsin, and chymotrypsin. 2. certain foreign proteins of non-enzymatic nature partially inhibited the reactivation of acid-inactivated invertase. 3. certain proteins as gelatin, lacto-globulin, and carbohydrate-free horse crystalbumin did not prevent the reactivation of invertase at all. 4. highly purified reactivated invertase was shown to exhibit an effect typical of original native ... | 1941 | 19873266 |
| equine encephalomyelitis in man. | 1941 | 19970570 | |
| equine encephalomyelitis. | 1941 | 20783793 | |
| epidemiology of encephalitis: western equine type, manitoba, 1941. | 1942 | 20322465 | |
| clinical findings in encephalitis (western equine). | 1942 | 20322466 | |
| purified diphtheria antitoxin in the ultracentrifuge and in the electrophoresis apparatus. | ultracentrifugation studies of diphtheria antitoxin showed that: 1. purified antitoxin of high activity obtained from horse plasma without enzymatic treatment has exactly the same sedimentation constant as the globulin fraction obtained in a similar way from normal horse plasma s(20) (water) = 6.9 x 10(-13). 2. purified antitoxin obtained with trypsin digestion of the toxin-antitoxin complex has a sedimentation constant of s(20) (water) = 5.5 +/- 0.1 x 10(-13), a diffusion constant of d(20) (wat ... | 1942 | 19873288 |
| a further study of the cross reaction between the specific polysaccharides of types iii and viii pneumococci in horse antisera. | 1. the cross reaction of the specific polysaccharide of type viii pneumococcus with type iii antipneumococcus horse serum has been studied quantitatively and found similar to the s iii-anti-s viii reaction. 2. contrasted with the general similarity of the two-segment reaction curves were distinct qualitative and quantitative differences in the course and character of the reciprocal reactions with respect to each segment. 3. these differences could be interpreted in terms of the known chemical di ... | 1942 | 19871166 |
| quantitative experiments with antibodies to a specific precipitate : iii. antigenic properties of horse serum fractions isolated by electrophoresis and by ultracentrifugation. | 1. rabbit antisera to a type ii pneumococcus specific precipitate from horse serum were tested with fractions prepared by ultracentrifugation and electrophoresis of normal and immune horse serum. 2. in one instance a rapidly sedimenting protein from normal horse serum had nearly the same quantitative antigenic properties toward the anti-antibody rabbit serum as did the purified pneumococcus antibody solutions previously reported. in another instance a comparable fraction removed only a part of t ... | 1942 | 19871172 |
| studies in rodent poliomyelitis : i. further experiments with the murine strain of sk poliomyelitis virus. | 1. sk murine virus maintained over more than 200 serial mouse passages increased in virulence for mice from an initial intracerebral titer of about 1:1 million to a maximum titer of not less than 1:1 billion dilution activity. 2. following intracerebral injection with murine virus of remote mouse passages, 5 of 13 rhesus monkeys developed a characteristic encephalitic syndrome. repeated intravenous injection of massive doses of virus caused localized flaccid paralysis in 2 of 14 monkeys. 3. intr ... | 1942 | 19871210 |
| studies in rodent poliomyelitis : iii. experimental poliomyelitis in guinea pigs produced with the murine strain of sk poliomyelitis virus. | 1. murine sk poliomyelitis virus has been transferred from mouse to guinea pig with the establishment of a fixed strain of cavian passage virus. 2. the disease thus produced in guinea pigs is characterized by the occurrence of flaccid paralysis. typical poliomyelitic lesions are found in the anterior horn of the spinal cord. 3. guinea pigs are susceptible to infection with murine virus by the intracerebral, intravenous, intraperitoneal, and subcutaneous route; cavian passage virus produces paral ... | 1942 | 19871219 |
| studies on eastern equine encephalomyelitis : vi. facilitation of infection in the mouse. | 50 per cent glycerine injected intraperitoneally, intramuscularly, or intravenously, greatly enhances the activity of equine encephalomyelitis virus injected intramuscularly, increasing its virulence up to 100-fold. the same effect is produced by very concentrated sodium chloride. the result appears due to dehydration of the nervous system, suddenly produced. gradual withdrawal of body fluids, produced by depriving animals of drinking water, results in sharp concentration of the blood, equal to ... | 1942 | 19871240 |
| induced resistance of the central nervous system to experimental infection with equine encephalomyelitis virus : i. neutralizing antibody in the central nervous system in relation to cerebral resistance. | 1. neutralizing antibody to equine encephalomyelitis virus was found in the spinal fluid of rabbits sufficiently vaccinated with active or formalin-inactivated virus. antibody was specific for the western or for the eastern virus. 2. neutralizing capacity of spinal fluid was equivalent to that of a 1/300 dilution of serum of the same animal, and was of the same order of magnitude as that of perfused brain of a vaccinated animal. 3. vaccinated rabbits which showed antibody in the spinal fluid res ... | 1942 | 19871243 |
| serological reactions of protein films and denatured proteins. | films of several proteins, hen ovalbumin, horse and human serum albumins, and globulins were found to combine specifically with antibodies, showing that the reactions can take place independently of the structure which secures the compact shape of the protein molecule. serum globulin films differed from ovalbumin in that they lost their reactivity when kept on the water surface. species specific reactions were observed with films of serum albumin and suitably diluted antisera, and likewise in th ... | 1942 | 19871249 |
| quantitative studies of the photochemical despeciation of horse serum : an approach to the problem of intravenous foreign protein therapy. | 1. normal horse serum was irradiated for periods of 3 to 4 days, with visible light or with ultraviolet light of known intensity and wave length. the photosensitizer hematoporphyrin was employed in some instances. the serum was exposed to the air in thin layers, and thoroughly agitated throughout irradiation. 2. the irradiated sera were unchanged in color, and over 90 per cent of the original protein content remained precipitable by phosphotungstic acid. 3. studies of the antigenicity of the ser ... | 1942 | 19871250 |
| the antigenic properties of native and regenerated horse serum albumin. | 1942 | 17809983 | |
| cross-immunity studies: between venezuelan equine encephalomyelitis virus and eastern, western, and argentine virus. | 1942 | 17647915 | |
| human equine encephalomyelitis and st. louis encephalitis in california, 1939-1941. | 1942 | 18015614 | |
| the osmotic pressure of foetal horse-serum albumin. | 1942 | 16991564 | |
| mosquito vectors and inapparent animal reservoirs of st. louis and western equine encephalitis viruses. | 1943 | 18015747 | |
| encephalitis (western equine) in manitoba-1941. | 1943 | 18015849 | |
| can phenothiazine become toxic: for horse after passage through pigs. | 1943 | 17647974 | |
| camel, horse and bison associated with human burials and artifacts near fresno, california. | 1943 | 17798332 | |
| the virus of infectious feline agranulocytosis : ii. immunological relation to other viruses. | the infection of cats by the virus of infectious feline agranulocytosis is followed by the production of specific neutralizing and protective antibodies, and recovery from the disease is associated with the development of solid immunity to reinfection. from the evidence presented it is obvious that the virus is not related to the viruses of hog cholera, lymphocytic choriomeningitis, fox encephalitis, vesicular stomatitis, the western type of equine encephalomyelitis, herpes, and b virus infectio ... | 1943 | 19871264 |
| complement fixation with the neurotropic viruses. | antigens capable of fixing complement specifically with the appropriate antibodies have been prepared from brain tissue of hamsters and mice infected with the viruses of st. louis, japanese, western, and eastern encephalitis, and with the west nile virus. the antigens were freed of the material which reacts with normal serum by means of centrifugation at relatively high speed. in addition, the infectivity of the preparation was destroyed by irradiation with ultraviolet light. cross reactions wer ... | 1943 | 19871270 |
| the effect of salicylates on the precipitation of antigen with antibody. | 1. sodium salicylate modifies the precipitation of normal rabbit serum protein by sodium tungstate, and partially inhibits the precipitation of horse serum euglobulin by rabbit antiserum. sodium salicylate added to a system containing crystalline egg albumin and its antibody partly prevents the formation of precipitate, the degree of inhibition being related to the concentration of salicylate. 2. precipitation in the equivalence zone is more readily prevented by salicylate than precipitation in ... | 1943 | 19871273 |
| mammalian red cells as a source of "small particles". | 1. small particles essentially similar to those previously isolated from other tissues have been isolated from mammalian red blood cells (horse blood). 2. about one-third of the dry weight of the particles is lipids. 3. the particles produce hemolysins against the homologous erythrocytes when inoculated into a foreign species. 4. the fact that the particles can be isolated from mammalian red cells which do not contain visible granules is taken to indicate that some at least of the particles isol ... | 1943 | 19871285 |
| the course of experimental infection of the chick embryo with the virus of equine encephalomyelitis. | the titration curve for the virus of eastern equine encephalomyelitis inoculated into the 10 day old chick embryo shows that the maximum increase in virus content continues until shortly before the generalized destruction of the embryo is apparent. this is followed by a stationary phase. histological studies of infected embryos fail to demonstrate selective tissue destruction, and titrations show the virus to be distributed throughout the egg, although concentrated in the embryo. the chorioallan ... | 1943 | 19871287 |
| induced resistance of the central nervous system to experimental infection with equine encephalomyelitis virus : ii. serotherapy in western virus infection. | under none of the experimental conditions here described was treatment of the infection induced by the virus of western equine encephalomyelitis in mice and guinea pigs with specific hyperimmune rabbit serum effective if begun after the onset of signs of encephalitis. in mice, after intracerebral inoculation of virus, serum was ineffective when given even before that stage. after peripheral introduction of virus in guinea pigs the disease was completely arrested in certain animals by single or m ... | 1943 | 19871290 |
| immunity to yellow fever encephalitis of monkeys and mice immunized by neural and extraneural routes. | monkeys and mice surviving cerebral infection with yellow fever virus of relatively avirulent strains have been found to resist maximal intracerebral doses of yellow fever virus of a highly neurotropic strain. such animals, however, do not resist more than very small doses of intracerebrally inoculated virus of eastern equine encephalomyelitis. animals immunized by extraneural routes, on the other hand, are not uniformly resistant to neural infection with neurotropic yellow fever virus. monkeys ... | 1943 | 19871299 |
| venezuelan equine encephalomyelitis in man. | a filterable agent was isolated from the blood and from washings of the upper respiratory passages of a young laboratory worker during a mild, acute, febrile illness. this agent was identified as a strain of venezuelan equine encephalomyelitis virus. circulating specific complement-fixing and neutralizing antibodies not present in sera withdrawn during the acute phase of illness were demonstrated in sera obtained during convalescence. a fellow laboratory worker who became similarly ill simultane ... | 1943 | 19871301 |
| antigenic properties of native and regenerated horse serum albumin. | comparative immunological measurements have been carried out on crystalline horse serum albumin in the native state and after regeneration from 8 m urea solutions. the mean antigenic activity of the regenerated protein has been found to be less than 10 per cent of that of the native, whereas both antigens proved to be immunologically equivalent. the problem of the relation between protein denaturation and immunological activity has been considered and discussed on the basis of known physical and ... | 1943 | 19871305 |
| further studies on the titration and neutralization of the western strain of equine encephalomyelitis virus in tissue culture. | 1. titration and neutralization of the western strain of equine encephalomyelitis virus can be carried out in vitro by means of tissue culture. 2. the in vitro titration test as presented is a more sensitive method than animal inoculation. 3. tissue culture may be better than animal inoculation for the detection of small amounts of virus. 4. the neutralization obtained in tissue culture is 100 to 1,000 times greater than that observed in the intracerebral test in mice and is comparable to the po ... | 1943 | 19871313 |
| laboratory transmission of western equine encephalomyelitis virus by mosquitoes of the genera culex and culiseta. | 1. western equine virus has been successfully transmitted in the laboratory by 3 species of mosquitoes from 2 genera not previously reported as laboratory vectors: culex tarsalis, culiseta inornata, and culiseta incidens. 2. though transmission was not demonstrated, survival of the virus for more than a few days was shown to occur in culex stigmatosoma and psorophora confinnis. possibly transmission occurred by the former. 3. in experiments with culex tarsalis, infection of the mosquitoes occurr ... | 1943 | 19871339 |
| depression of anaerobic glycolysis of embryonic tissue by western strain of equine encephalomyelitis virus. prevention of this effect by specific immune serum. | studies were made on the effect of mixing the western strain of equine encephalomyelitis virus (w.e.e.) and embryonic tissue on the rate of anaerobic glycolysis of the tissue. whole chick embryo, chick embryo from which brain and spinal cord had been removed, and embryonic skeletal muscle were employed. 1. w.e.e. virus depressed the rate of anaerobic glycolysis of embryonic tissues within 2 days after its addition to the tissue. the decrease in anaerobic glycolysis varied from 17 to 82 per cent ... | 1944 | 19871358 |
| induced resistance of the central nervous system to experimental infection with equine encephalomyelitis virus : iii. abortive infection with western virus and subsequent interference with the action of heterologous viruses. | although vaccination of guinea pigs with formalin-inactivated western equine encephalomyelitis virus rendered them specifically immune to an intracerebral challenge dose of 1,000 m.l.d. of western virus, it failed to protect their central nervous system against the initial effects of the virus: the intracerebral challenge dose was followed by an abortive infection of 20 to 30 hours' duration characterized by fever and histopathological changes which simulated the response at that early stage of ... | 1944 | 19871408 |
| specificity in the effects on brain metabolism of two differing neurotropic viruses. | 1. brain tissue infected with the virus of western equine encephalomyelitis shows specific differences in metabolism from brain tissue infected with the virus of poliomyelitis. 2. with added glucose concentration of 121 mg. per cent, oxygen utilization of poliomyelitic brain is significantly below normal and that of encephalitic brain is not. 3. with added glucose concentration of 217 mg. per cent, oxygen utilization of encephalitic brain is significantly below normal and that of poliomyelitic b ... | 1944 | 19871412 |
| parallelism in the lethal and hemolytic activity of the toxin of clostridium septicum. | the relation of the lethal toxin to the hemolysin produced by clostridium septicum, strain 44, has been investigated. the following results suggest that the hemolytic and lethal actions of crude toxin are functions of a single substance or that they are functions of two substances which have similar physical, chemical, and antigenic properties. (1) within the limits of experimental error, the lethal activity of cultures is directly proportional to their hemolytic activity. (2) treatment of a cul ... | 1944 | 19871418 |
| chronic equine encephalitis. | 1944 | 19970752 | |
| african horse sickness. | 1944 | 21004208 | |
| vaccination of equines for the prevention of african horse sickness. | 1944 | 21004209 | |
| "horse serum" a compound word. | 1944 | 17833670 | |
| fatal encephalitis in man due to the venezuelan virus of equine encephalomyelitis in trinidad. | 1944 | 17844380 | |
| interference between st. louis encephalitis virus and equine encephalomyelitis virus (western type) in the chick embryo. | interference between two unrelated viruses is reported. equine encephalomyelitis virus grows only to a limited degree, if at all, when injected into chick embryos in which st. louis encephalitis virus is being propagated. | 1944 | 17815105 |
| equine infectious anaemia: an outbreak in the ottawa valley. | 1944 | 17648046 | |
| equine infectious anemia: an outbreak in the ottawa valley. | 1944 | 17648052 | |
| western equine encephalomyelitis infection: comparison of neutralization and complement fixation tests. | 1944 | 17648069 | |
| venezuelan-type equine encephalomyelitis virus in trinidad. | 1944 | 17741327 | |
| studies on cholinesterase: 4. purification of pseudo-cholinesterase from horse serum. | 1944 | 16747753 | |
| ferrihaemoglobinaemia (methaemoglobinaemia) in man and the horse. | 1944 | 16747836 | |
| pathogenesis of venezuelan equine encephalomyelitis virus infections in the developing chick embryo. | 1944 | 16560852 | |
| recovery of equine encephalomyelitis virus (western type) from chicken mites. | the western type of equine encephalomyelitis virus has been isolated from chicken mites (dermanyssus gallinae) in nature during an outbreak of the equine disease in the southwest. | 1945 | 17780323 |
| fistulous withers in a horse. | 1945 | 17648093 | |
| equine infectious anaemia: attempted vaccination with crystal violet tissue vaccine. | 1945 | 17648142 | |
| successful treatment of experimental western equine encephalomyelitis with hyperimmune rabbit serum. | 1945 | 18016211 | |
| [not available]. | 1945 | 18902603 | |
| an equine hermaphrodite. | 1945 | 21005489 | |
| treatment of strangles in a horse with penicillin and sulfamerazine. | 1945 | 21005491 | |
| a review of the epizootiology of equine encephalomyelitis in the united states. | 1945 | 21005494 | |
| fracture of the second phalanx (os corona) in a horse, due to enemy action. | 1945 | 21005525 | |
| a genetic analysis of the american quarter horse. | 1945 | 21005993 | |
| horse brain thromboplastin; effect of various factors on activity of horse brain extracts. | 1945 | 21006290 | |
| gonadotropic activity of equine gonadotropin in combination with zinc. | 1945 | 21006700 | |
| anaphylactic properties of photo-oxidized rabbit-antisera (vs sheep erythrocytes and pneumococci) and horse-antiserum (vs diphtherial toxin) containing univalent antibodies. | 1945 | 21007100 | |
| protective value of univalent antibodies produced by photo-oxidation of antipneumococcal rabbit-serum and antidiphtheric horse-serum. | 1945 | 21007101 | |
| an electrophoretic study of an anti-influenzal horse serum. | 1945 | 21007104 | |
| additional outbreaks of equine encephalomyelitis in new jersey pheasants. | 1945 | 21008180 | |
| hydatid cysts in the horse. | 1945 | 21008190 | |
| serologic distinctness of eastern, western, and venezuelan equine encephalomyelitis viruses. | 1945 | 21004048 | |
| combined anesthesia and hyperimmune serum therapy in the treatment of experimental western equine encephalomyelitis. | 1945 | 21004067 | |
| [study of horse fatigue on change of step length]. | 1945 | 21027844 | |
| the treatment of equine colic. | 1945 | 21028681 | |
| infectious equine encephalomyelitis in the united states in 1944. | 1945 | 21009471 | |
| hypersensitivity to horse serum. | 1945 | 21008812 | |
| [not available]. | 1945 | 21020456 | |
| [not available]. | 1945 | 21024468 | |
| [not available]. | 1945 | 21024473 | |
| hydronephrosis in one half of a horse-shoe kidney. | 1945 | 21021957 | |
| [not available]. | 1945 | 21022125 | |
| penicillin and antitoxin in equine tetanus. | 1945 | 21065379 | |
| chemical studies on bacterial agglutination : vii. a quantitative study of the type specific and group specific antibodies in antimeningococcal sera of various species and their relation to mouse protection. | 1. the quantitative method for the estimation of agglutinins has been applied to antimeningococcal horse, rabbit, and chicken sera and to the sera of humans convalescing from meningococcus meningitis. the type-specific and group-specific agglutinin n can be measured, using homologous and heterologous suspensions of meningococci. 2. type i horse, rabbit, and chicken antimeningococcal sera contain considerable amounts of antibody which cannot be removed either by type ii meningococcus suspension o ... | 1945 | 19871438 |
| studies on meningococcal infection : xiii. correlation between antipolysaccharide and the antibody which protects mice against infection with type i meningococci. | absorption tests indicated that the protective antibody (type i) in four antimeningococcal horse sera corresponded closely to one of the components of the polysaccharide preparation previously isolated by the authors from type i meningococci. this antibody was, however, a minor fraction in the three therapeutic sera tested, being secondary in amount to non-protective antibody corresponding to another component of the polysaccharide preparation, plus antibody corresponding to agar. in one case, r ... | 1945 | 19871446 |
| immunochemical properties of native and denatured horse serum globulins. | 1. the influence of guanidine hydrochloride on the denaturation and regeneration of type i antipneumococcal horse serum globulin was determined by measurements of viscosity, diffusion, and sedimentation in the ultracentrifuge. in addition, the effect of nacns on the antibody globulin was studied. 2. both the irreversibly denatured and the regenerated fractions were found to be precipitable by si. the observed changes in combining ratio have been tentatively explained in terms of (a) changes in t ... | 1945 | 19873431 |
| use of horse meat infusions in culture mediums. | 1945 | 16560891 | |
| cleavage stages of the ova of the horse, with notes on ovulation. | 1945 | 17104976 | |
| molecular association of hemocyanin produced by x-rays as observed in the ultracentrifuge. | 1. when normal, monodisperse hemocyanin (60.5s) from limulus rolyphemus was irradiated in neutral buffer with x-rays, several new, more rapidly sedimenting ultracentrifugal components (86s, 107s, 122s) were produced, with a corresponding loss in the amount of the unaffected protein. the amount of the effect was roughly proportional to the amount of irradiation. 2. the new resolvable components apparently represented an association of the primary particles into aggregates of 2, 3, and 4 primary p ... | 1946 | 19873487 |
| western equine encephalomyelitis virus in the blood of experimentally inoculated chickens. | 1. chickens inoculated subcutaneously with 0.2 cc. of a 10(-2) to 10(-7) dilution of western equine mouse brain virus had the virus in the blood serum between the 12th and the 48th hour in most instances. the fowls showed no signs of illness. 2. viremia could be induced regularly in chickens by inoculating subcutaneously the least amount of virus which would produce encephalitis in the mouse when inoculated by the intracerebral route. 3. even the minimal infecting dose for a chicken led to such ... | 1946 | 19871522 |
| st. louis encephalitis virus in the blood of experimentally inoculated fowls and mammals. | 1. of three species of mammals tested by peripheral inoculation (guinea pig, cat, and horse) none showed viremia under conditions which suggested that any of these species would serve as a frequent source of mosquito infection. 2. of the birds tested (chicken, duck, and dove) all developed viremia and might readily serve as natural sources of mosquito infection. chickens were shown to be very highly susceptible to infection by minute amounts of virus inoculated subcutaneously. 3. virus may appea ... | 1946 | 19871523 |
| laboratory transmission of japanese b encephalitis virus by seven species (three genera) of north american mosquitoes. | in the present studies ten common species of western north american mosquitoes have been tested for their ability to act as vectors of japanese b encephalitis virus (see summary table xii). the strain of japanese b encephalitis virus which was used was adapted to direct mouse brain passage, probably a disadvantage, but no freshly isolated strain was available. of the ten species of mosquitoes tested, seven were demonstrated to be laboratory vectors. these seven species represent three genera (cu ... | 1946 | 19871524 |
| interference between viruses in tissue culture. | the influence of one virus on the growth of another in tissue culture was investigated. the 17dd high strain of yellow fever virus was found capable of completely suppressing the growth of both the asibi strain of the same virus and of the heterologous west nile virus, even when these were added to the cultures in large amounts. the 17dd high strain of yellow fever virus and the west nile virus produced either partial or complete suppression of growth of the venezuelan equine encephalomyelitis v ... | 1946 | 19871525 |
| plasma substitutes : human and animal globin related to the production of hemoglobin and plasma protein dog hemoglobin utilization improved by methionine but not by isoleucine. | hemoglobin and globin alone, supplemented, or modified in various ways are seriously considered as plasma substitutes. human globin given to doubly depleted (anemic and hypoproteinemic) dogs by vein contributes to the production of new hemoglobin and plasma protein, but there is some toxicity and weight loss. dog hemoglobin given intraperitoneally is better tolerated and somewhat more completely utilized with more blood proteins formed and less weight loss. dog globin (tryptic digest) given by v ... | 1946 | 19871535 |
| effect of in vitro cultivation on the pathogenicity of venezuelan equine encephalomyelitis virus. | continued in vitro cultivation in a maitland type medium resulted in a marked modification of the extraneural pathogenicity of the venezuelan equine encephalomyelitis virus. the ability of the virus to induce lethal infections after peripheral inoculation was almost completely lost for mice 42 or more days of age, was somewhat reduced for mice 28 days of age, but was still retained for mice 21 or less days of age. the virulence of the virus by the cerebral route remained essentially unaffected f ... | 1946 | 19871564 |
| influence of anesthesia on experimental neurotropic virus infections : i. in vivo studies with the viruses of western and eastern equine encephalomyelitis, st. louis encephalitis, poliomyelitis (lansing), and rabies. | anesthesia with diethyl ether significantly alters the course and outcome of experimental infections with the equine encephalomyelitis virus (eastern or western type) or with the st. louis encephalitis virus. no comparable effect is observed in experimental infections produced with rabies or poliomyelitis (lansing) viruses. the neurotropic virus infections altered by ether anesthesia are those caused by viruses which are destroyed in vitro by this anesthetic, and those infections not affected by ... | 1946 | 19871570 |
| two cases of horse-shoe kidney. | 1946 | 20323983 | |
| physiology in horse-racing. | 1946 | 20341080 |