Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| experimental dirofilariasis in macaques. iii. susceptibility and host responses to dirofilaria tenuis of raccoons. | in this third of a series of studies on experimental dirofilariasis in primate hosts, 3 macaca cynomolgus, 6 m. speciosa, and 2 m. mulatta were inoculated with infective larvae of dirofilaria tenuis, a parasite of the raccoon, and were killed at periods ranging from 2 weeks to 13 months of infection. one m. mulatta and one m. speciosa were treated daily with prednisolone beginning 2 months after inoculation; worms were recovered from these and 5 other monkeys (7 of 11). microfilaremia was detect ... | 1976 | 816216 |
| thalamic projections from the precentral motor cortex in macaca fascicularis. | radioactive amino acids were injected into area 4 in 7 monkeys (macaca fascicularis). ipsilateral corticothalamic projections were traced to olszewski's nucleus ventralis lateralis pars oralis and pars medialis, the nucleus ventralis posterior lateralis pars oralis, the nucleus ventralis posterior medialis and inferior and to the nucleus reticularis. some fibers appeared to terminate in the ipsilateral nucleus ventralis lateralis pars caudalis, the nucleus lateralis posterior and the nucleus sub ... | 1976 | 816421 |
| immunization of macaca fascicularis (macaca irus) monkeys with streptococcus mutans: specificity of antibody responses in saliva. | m fascicularis monkeys were immunized subcutaneously in the vicinity of the major salivary glands and by retrograde infusion into the parotid duct, with a vaccine containing formalin-killed s mutans strain 6715 cells and culture-fluid antigens. indirect immunofluorescent staining was used to titrate and classify antibodies. subcutaneous immunization induced only a serum response, whereas intraductal infusion stimulated both an iga antibody response in the parotid fluid and a serum response. immu ... | 1976 | 816835 |
| protrusions of the inner wall of schlemm's canal. | large specific protrusions of the trabecular meshwork into schlemm's canal (hernias) have been suggested to be the main drainage routes for aqueous humor, similar to the function of the arachnoid villi in draining the cerebrospinal fluid. my quantitative study in cynomolgus monkeys does not support such a hypothesis. the drainage routes of the aqueous humor, evaluated from the number and sizes of the pores observed by scanning electron microscopy, were as common through the hernias as through ot ... | 1976 | 826163 |
| blood groups of bonnet macaques (macaca radiata), with a brief introduction to seroprimatology. | the human-type a-b-o blood groups of 52 bonnet macaques (macaca radiata) were determined. application of method of population genetics indicated the gene frequences to be 0 = 0.173, a = 0.480 and b = 0.347. cross testing of sera and red cells of the bonnet macaques revealed two blood-type-specific isoagglutinins, one of them strong enough for use as a blood typing reagent. no blood group polymorphism was revealed by testing bonnet macaque red cells with isoantisera produced in rhesus monkeys (m. ... | 1976 | 826172 |
| influence of cholinergic receptor blockade on drug-induced prolactin release in the monkey. | the influence of varying doses of perphenazine, thyrotropin-releasing hormone (trh) and serotonin on prolactin release was examined in two species of monkeys: rhesus (macaca mulatta) and crab-eating (macaca fascicularis). the intravenous administration of 0.33 mg/kg body weight of perphenazine or 1.0 mug/kg body weight of trh gave a greater release of prolactin than higher doses of perphenazine (1.0 mg/kg) or trh) (3.4 mug/kg), respectively. prolactin release induced by serotonin at doses of 1, ... | 1976 | 826472 |
| [antifertility effect of an active immunization of monkeys with human pregnancy-specific beta 1-glycoprotein (sp1) (author's transl)]. | fertile female cynomolgus monkeys (macaca fascicularis) were actively immunized against human pregnancy-specific beta 1-glycoprotein (sp1). native sp1 as well as chemically modified derivatives of sp1 served as antigens. the effect of the immunization on reproduction in these animals was investigated. the immunized monkeys showed a significant reduction in fertility: the conception rate in these animals was only slightly reduced when compared with the controls; but in the immunized monkeys pregn ... | 1976 | 827272 |
| effect of malnutrition on cortisol-binding protein in the lens of cynomolgus monkeys. | a cortisol-binding protein exists in the lens of cynomolgus monkeys as in other species. the cortisol-binding capacity decreased markedly with a diet either moderately or severely depleted of protein, even if the diet was later changed to a normal diet during infancy. this suggests that malnutrition may cause insufficient synthesis of the important factors controlling the inactivation of steroid hormone in the lens. | 1976 | 823312 |
| atherosclerosis in rhesus and cynomolgus monkeys. | 1976 | 813206 | |
| an outbreak of epistaxis in cynomolgus monkeys (macaca fascicularis). | 1976 | 826008 | |
| failure of carbon monoxide to induce myocardial infarction in cholesterol-fed cynomolgus monkeys (macaca fascicularis). | twenty-six adult female cynomolgus monkeys (macaca fascicularis) were randomly assigned to four groups which were fed on a standard laboratory diet or a semipurified diet containing cholesterol. in two of the groups, the monkeys were exposed intermittently to co throughout the day for 14 months; the control animals breathed room air. no myocardial infarctions were observed, and the ecg showed a transitory injury current in only one animal. no differences in plasma cholesterol levels or in aortic ... | 1976 | 815001 |
| the effect of entrapment in liposomes on the in vivo distribution of [3h]methotrexate in a primate. | entrapment of methotrexate (mtx) plus [3',5', 9(n)-3h]methotrexate into positively charged liposomes greatly alters the subsequent distribution of [3h]mtx in a cynomologous monkey (macaca irus) after a single i.v. injection ([3h]mtx; refers to total radioactivity derived from purified [3h]mtx). when [3h]mtx is incorporated into small, sonically disrupted liposomes, the level of the entrapped [3h]mtx in the total plasma volume was still 50% of the total injected dose after 4 hr, which is 100 time ... | 1976 | 819137 |
| evaluation and re-evaluation of genetic radiation hazards in man. ii. the arm number hypothesis and the induction of reciprocal translocations in man. | the arm number hypothesis proposed by brewen and collagues in 1973 has been examined in the light of information thus far available from mammalian studies. in experiments with peripheral blood lymphocytes (radiation in vitro), a linear relationship between dicentric yield and the effective chromosome arm number of the species was obtained in the mouse, chinese hamster, goat, sheep, pig, wallaby and man. however, the data are not consistent with such a relationship in several primate species (ma ... | 1976 | 819823 |
| [nursing procedures for cynomolgus monkey infants (author's transl)]. | this paper describes the results of the artificial nursing of 8 infant cynomolgus monkeys (macaca fascicularis) weighing 230-350 g at birth. the infants were separated from their mothers just after or 2 days after birth and were kept in a specially deviced small cage (photo 1 & 2). they were fed on 6.4-16.6% solution of a commercially available powdered milk for the human baby. apple juice also was given to them from the 3rd or 4th week on. in about the 6th week, the infants received solid foods ... | 1976 | 820560 |
| [surface structure of the lips and tactile hairs of cynomolgus monkeys. scanning electron microscopic studies on the transitional part between the skin and mucosa 1]. | 1976 | 821303 | |
| applanation tonometry in the conscious cynomolgus monkey (macaca fascicularis). | four monkeys (macaca fascicularis) were trained to tolerate applanation tonometry while fully conscious. the tonometer used was the draeger tonometer with an applanation area of 3.06 diameter, but with a reduced application surface (4 mm instead of 6.8 mm diameter). the reduction did not change the calibration and is applicable in this monkey species without any correction factor. the mean intraocular pressure determined was 19.12 mmhg. | 1976 | 821306 |
| effect of bran and cholestyramine on plasma lipids in monkeys. | semipurified diets whose cholesterol content varied from 34 to 120 mg/100 kcal were given to adult female cynomolgus monkeys (macaca fascicularis) for 9 months. the intake of dietary fiber was increased through the addition of wheat, rice, or soya bran; 5% cholestyramine was given to one group of monkeys. none of the brans reduced plasma levels of cholesterol, whereas cholestyramine produced marked hypocholesterolemic effects. triglyceride levels increased with higher cholesterol intake, but no ... | 1976 | 821335 |
| metabolism of 16,16-dimethyl-prostaglandin f2alpha in the cynomolgus monkey and the human female. | 1976 | 821483 | |
| proline-rich proteins in membranes and contents of monkey (macaca irus and cercopithecus aethiops) parotid zymogen granules. | 1976 | 821460 | |
| disynaptic inhibition of spinal motoneurones from the motor cortex in the monkey. | 1. the neuronal mechanism of disynaptic inhibition of spinal motoneurones by the corticospinal tract was investigated in macaca irus. surface stimulation or weak intracortical stimulation was used in order to evoke the inhibition. intracellular records were taken from motoneurones in lumbar segments. 2. both the disynaptic i.p.s.p.s evoked from group ia afferents and the disynaptic i.p.s.p.s evoked from corticospinal fibres were found to be depressed by conditioning stimulation of motor axons to ... | 1976 | 822152 |
| responses of subthalamic and pallidal neurons to striatal stimulation: an extracellular study on awake monkeys. | the unitary activity of subthalamic neurons (corpus luysii) and of gp neurons was recorded extracellularly on awake monkeys (macaca cynomolgus). striatal stimulation induces in subthalamic (sth) neurons a short latency spike discharge (10-15 msec) followed by a long lasting depression of the spontaneous activity. as, according to anatomical studies, the subthalamic nucleus is principally connected to the globus pallidus (gp), electrophysiological relations between striatal and gp neurons and bet ... | 1976 | 820409 |
| identification, classification and anatomical segregation of cells with x-like and y-like properties in the lateral geniculate nucleus of old-world primates. | 1. all the cells (158) that we studied in the lateral geniculate nuclei of macaca nemestrina and macaca irus could be distinguished as either x-like or y-like on the basis of their responses to tests developed to classify cat retinal and lateral geniculate nucleus cells. these tests include responses to stationary spots, fast moving wands and moving gratings. 2. response latencies to electrical stimulation of the optic chiasm were determined for 130 cells; no x-like cell showed a latency shorter ... | 1976 | 822151 |
| effects of paracentesis on the blood-aqueous barrier: a light and electron microscopic study on cynomolgus monkey. | the effects of paracentesis on the blood-aqueous barrier of cynomolgus monekeys were studied by light and electron microscopy. the following regions of the eye were examined: ciliary body, iris, schlemm's canal, juxtacanalicular connective tissue, and trabecular meshwork. prominent structural alterations were seen in the ciliary epithelium at the anterior portion of the pars plicata, but the epithelium at the posterior portion of the pars plicata and at the pars plana appeared less disrupted. pl ... | 1976 | 824223 |
| priming of macaca cynomolgus philippinensis with purified antigen of brucella melitensis before injection of rev. i vaccine. | in experiments designed for study of bacteremia and serologic response of macaca cynomolgus philippinensis to vaccination with a soluble antigen (fraction i) of brucella melitensis and the live rev. i vaccine strain, fraction i and rev. i were administered both four weeks apart and simultaneously. one of three monkeys given the vaccines four weeks apart and two of three monkeys vaccinated with fraction i and rev. i in a single injection developed transient bacteremia, as shown by blood cultures. ... | 1976 | 824373 |
| oral glucose tolerance test in the cynomolgus monkey (macaca fascicularis). | the glucose tolerance test was simplified so that it could be performed on more than one cynomolgus monkey (macaca fascicularis) at a time. glucose was administered orally in a dose of 2 g/kg body weight as a 50% aqueous solution, and blood samples were taken just before and 30 minutes and 150 minutes after glucose administration. the simplified test was conducted on a total of 93 cynomolgus monkeys. glucose tolerance curves obtained by this method were classified into three patterns with regard ... | 1976 | 824499 |
| monkey antisera with increased specificity to carcino-embryonic antigen (cea). | three macaca irus monkeys were immunized with purified human cea. one received unmodified cea and two were immunized with haptenated (4-hydroxy-5-iodo-3-nitrophenyl acetyl) cea. all three monkeys formed precipitating antibodies to cea. the antisera did not precipitate the cea-related normal glycoprotein antigen (nca). in contrast, cea-immunized rabbits, sheep and goats invariably form antibodies against nca. radio-immunoassays showed the monkey antisera to contain trace amounts of antibodies to ... | 1976 | 1254359 |
| the effects of prostaglandin e1 on the ciliary epithelium and the drainage angle of cynomolgus monkeys: a light- and electron-microscopic study. | 1976 | 1269539 | |
| studies on the interaction between coxsackievirus a9 and hela cells. i. plaque-forming ability of coxsackievirus a9 in hela cell cultures. | most of the coxsackievirus a9 (ca 9 virus) including the prototype strain formed plaques in hela cell monolayers under agar overlay, although they showed little or no cytopathogenicity under fluid medium. these viruses were isolated or passaged in primary cynomolgus monkey kidney (mk) cell cultures, and the infectivity of any strain in terms of plaque-forming units was much higher in mk cells than in hela cells, even after plaque purification of the virus in hela cell cultures. ca 9 virus contai ... | 1976 | 184325 |
| monkeypox-specific antibodies in human and simian sera from the ivory coast and nigeria. | a test for monkeypox-specific antibodies is described. monkeypox immune sera can be made type-specific by immunoabsorption with heterotypic poxvirus extracts. monkeypox-specific antibodies were demonstrated in sera from 9 cynomolgus monkeys (macaca fascicularis) that had previously been experimentally infected with monkeypox. monkeypox-specific antibodies were found in 3 wild-caught african monkeys (cercopithecus spp.) and in 3 human sera collected from africans in the ivory coast and nigeria 3( ... | 1976 | 186210 |
| perinephritis hypertension in monkeys. i. an increase of plasma renin activity associated with increased permeability of retinal vessels and angionecrosis. | the renal parenchyma of 5 crub-eating monkeys (macaca irus) was wrapped by cellophane, and plasma renin activity, blood pressure and vascular permeability of ocular ground were measured in comparison with 5 unoperated control monkeys. the results demonstrated that increases of systolic arterial pressure, plasma renin activity, and permeability of the retinal vessels were found in 4 operated monkeys. there was no such abnormal finding in the unoperated control monkeys. generally there was a rough ... | 1976 | 6807 |
| pneumococcal leptomeningitis in cynomolgus monkeys (macaca fascicularis). | 1976 | 10668 | |
| production of ra27/3 rubella vaccine and clinical results with the vaccine. | adaptation of rubella virus to human diploid cell strains was achieved in 1964, with attenuation in the same cells being accomplished by 1967. the production of rubella vaccine in hdcs is featured by the long period required to build up high titer. high multiplicity of infection gives optimal results. since rubella virus does not produce a cytopathic effect in hdcs, virus harvests must be made blindly and titrated individually before pooling. a unique feature of this cell-virus relationship is t ... | 1976 | 1031691 |
| light and electron microscopic histochemistry of the serous secretory granules in the salivary glandular cells of the mongolian gerbil (mongolian meridianus) and rhesus monkey (macaca irus). | 1977 | 71867 | |
| surface antigenic characteristics of human glial brain tumor cells. | the surface antigenic characteristics of human glial brain tumor (hgbt) cells were studied by complement-dependent cytotoxic antibody assays and indirect membrane immunofluorescence. eight permanent, well-characterized cell lines derived from human gliomas were used for analysis with antisera raised by hyperimmunization of nonhuman primates (macaca fascicularis) with glioblastoma multiforme tissue or established hgbt cells lines. exhaustive absorption of these antisera to remove predominantly an ... | 1977 | 72598 |
| axoplasmic transport in ocular hypotony and papilledema in the monkey. | orthograde and retrograde axoplasmic transport were studied in optic nerve heads of seven hypotensive macaca fascicularis eyes. orthograde transport was studied by radioautography after intravitreal radioisotope injections. retrograde transport was studied in the same eyes by horseradish peroxidase injection into the dorsal lateral geniculate nuclei or optic tracts. three eyes had developed marked papilledema before injections. orthograde axoplasmic transport was blocked in swollen axons of the ... | 1977 | 70200 |
| the structure and function of acid proteases. vii. distribution and some properties of acid proteases in monkey tissues. | 1. the distribution of acid protease activity in various tissues of japanese monkey (macaca fuscata fuscata) was investigated with hemoglobin as a substrate at ph 3.0. the activity per protein weight in crude extracts was highest in spleen and lung, and decreased in the order: spleen, lung greater than kidney, testis greater than brain greater than liver, placenta greater than thyroid gland, muscle. the activity in crude muscle extract was about one-tenth those of spleen and lung. the activity p ... | 1977 | 14947 |
| orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey. | orthograde and retrograde axoplasmic transport have been studied in the optic nerve heads of 37 macaca fascicularis eyes with normal or elevated intraocular pressure (iop) produced by cannulation of the anterior chamber. orthograde transport was labeled by 3h-amino acids injected intravitreally and incorporated into retinal ganglion cell proteins. retrograde transport was studied in the same eyes by injecting horseradish peroxidase (hrp) into one or both optic tracts and dorsal lateral geniculat ... | 1977 | 67096 |
| comparative studies of several vaccinia virus strains by intrathalamic inoculation into cynomolgus monkeys. | from the comparative studies of the virulence of several vaccinia virus strains by intrathalamic inoculation into cynomolgus monkeys, the following results were observed. the cv1 virus was most virulent, the new york city board of health, ikeda, em63, and lister viruses were slightly less virulent, and dis and lc16 viruses least virulent. the characteristic findings were widespread inflammatory lesions in the meninges and choroid plexus which were closely associated with the replication of vacci ... | 1977 | 404993 |
| heart rate in caged macaca fascicularis. effects of short-term physical exercise. | electrocardiograms were recorded hourly for five days in 16 caged macaca fascicularis by means of a miniaturized ecg transmitter connected to two chest leads. the lowest heart rates were 135 +/- 35 (mean +/- sd, n= 31) beats/min at 5 a.m., and the highest were 192 +/- 22 (n = 29) beats/min at 3 p.m. sinus arrhythmia was common. eight of the animals were trained to exercise in a specially designed enclosed treadmill; their heart rates were recorded daily during two 10-min periods of running at 3. ... | 1977 | 406403 |
| blood groups of crab-eating macaques (macaca fascicularis) demonstrated by isoimmune rhesus monkey (macaca mulatta) sera. | twenty-one isoimmune sera produced in rhesus monkey (macaca mulatta) containing type-specific antibodies for simian-type red cell antigens were tested for their cross-reactivity with red cells from crab-eating macaques (m. fascicularis). the majority of the antisera gave cross-reactions determining polymorphisms in the red cells of crab-eating macaques, homologous to those of rhesus monkeys. these results attest to the close taxonomic realationship between the two species of macaques, and have t ... | 1977 | 406404 |
| atropine inhibition of echothiophate cataractogenesis in monkeys. | one cynomolgus and three vervet monkeys were treated topicall twice daily in one eye with 63 microgram of echothiophate iodide and 750 microgram of atropine sulfate. the opposite eyes were treated with echothiophate alone. the eyes treated with echothiophate alone all developed posterior and/or anterior subcapsular cataracts within 26 to 66 days. the echothiophate plus atropine-treated cynomolgus eye developed a cataracts of much delayed onset and lesser severity compared to its echothiophate-on ... | 1977 | 406884 |
| role of hypertension in ischemic heart disease and cerebral vascular disease in the cynomolgus monkey with coarctation of the aorta. | the role of hypertension in cardiovascular disease was studied in the hypertensive coarcted monkey during the feeding of an atherogenic and nonatherogenic diet. during the 15-month period of observation, half of the hypertensive coarcted monkeys developed cardiovascular disease which included heart failure, ischemic heart disease, stroke, and sudden death. there were no cardiovascular complications in the control normotensive monkeys except for one cholesterol-fed animal. the incidence of ischem ... | 1977 | 140028 |
| induction of subcapsular cataracts in cynomolgus monkeys by echothiophate. | sixteen eyes of 13 cynomolgus monkeys were treated topically twice daily with echothiophate iodide. the dosages were increased gradually over several weeks to plateau levels ranging from 125 to 500 mug daily. the opposite eyes of the ten unilaterally treated monkeys received a control solution (diluent) identical save for the absence of echothiophate. all 16 echothiophate-treated eyes developed posterior subcapsular cataracts and 15 developed anterior subcapsular cataracts. the lenses in all ten ... | 1977 | 402905 |
| light and electron microscopy of the anterior chamber angle structures following surgical disinsertion of the ciliary muscle in the cynomolgus monkey. | light and electron microscopic studies were done on 11 cynomolgus monkey eyes which had undergone total iris removal followed by surgical disinsertion of the ciliary muscle from the scleral spur 4.7 to 14.4 months earlier. anterior chamber perfusion to measure gross outflow facility had been performed one to nine times postoperatively. over most of the circumference in most eyes (1) the ciliary muscle had been retrodisplaced from the scleral spur and had reattached to the sclera more posteriorly ... | 1977 | 403150 |
| formation and drainage of aqueous humor following total iris removal and ciliary muscle disinsertion in the cynomolgus monkey. | aqueous humor formation (ahf), uveoscleral flow (u), gross outflow facility (cg), true facility of outflow from the anterior chamber (ct1), true facility of outflow from anterior chamber into the general circulation (ct2), and the pressure sensitivity of ahf (pseudofacility; cps) were determined in cynomologus monkey eyes which had undergone total iris removal or iris removal followed by ciliary muscle disinsertion. ahf was in the normal range in iridectomized-only eyes. ahf was present but redu ... | 1977 | 403151 |
| administration of human interferon to rabies virus-infected monkeys after exposure. | the treatment of rabies-infected cynomolgus monkeys (macaca fascicularis) with human interferon after exposure was studied. the monkeys were infected with rabies street virus by the intramuscular route; larger than or equal to 24 hr after infection, human interferon was administered intramuscularly or by lumbar spinal injection into the cerebrospinal fluid. whereas 90% of the infected untreated monkeys died, 40%-80% of animals treated with interferon survived. no or only low levels of neutralizi ... | 1977 | 404370 |
| efferent connections of cortical, area 8 (frontal eye field) in macaca fascicularis. a reinvestigation using the autoradiographic technique. | the efferent projections from the cortical area 8 (frontal eye field) have been re-examined in four adult monkeys (macaca fascicularis) by injecting small amounts of h3-proline into the rostral bank of sulcus arcuatus and using the autoradiographic tracing technique. ipsilateral cortical projections could be traced into specific areas of the depths of sulcus principalis, sulcus temporalis superior and sulcus intraparietalis. label was found contralaterally in area 8. subcortical connections were ... | 1977 | 403205 |
| composite pattern of circulating lh, fsh, estradiol, and progesterone during the menstrual cycle in cynomolgus monkeys. | 1977 | 408814 | |
| differences in the virulence of plasmodium knowlesi for macaca irus (fascicularis) of philippine and malayan origins. | this report summarizes the results of a comparative study of the virulence of the "s-m," h, and c strains of p. knowlesi for indian rhesus monkeys (macaca mulatta) and cynomolgus monkeys [m. irus (fascicularis)] of malayan (west malaysia) and philippine origins. each of the above strains produced fulminating, uniformly fatal infections in the rhesus monkey and mild, chronic infections, characterized by relatively low level parasitemias in cynomolgus monkeys of philippine origin. in striking cont ... | 1977 | 407808 |
| clinical and pathogenetic studies of medical lake macaque virus infections in cynomolgus monkeys (simian varicella). | the medical lake macaque (mlm) virus produced varicelliform eruptions in cynomolgus monkeys. not all experimentally infected monkeys developed overt disease; viremia was found, and specific antibodies were detected. specific lesions were found in skin, lymph nodes, and spleen. focal inflammatory lesions were present in liver, pancreas, and lung (after intratracheal instillation of virus). mlm virus was recovered from these and other organs. the temporal movements of mlm virus in and out of prima ... | 1977 | 192806 |
| a new paramyxovirus isolated from cynomolgus monkeys. | a new virus was isolated from cynomolgus monkeys for laboratory use imported from indonesia in july, 1973. the virus agglutinated erythrocytes of some avian and mammalian species and hemolyzed chick erythrocytes. the virus was eluted from the surface of chick red blood cells by its neuraminidase activity. the virus was inactivated by ether; its nucleic acid was rna. on electron micrographs, the particles varied from 250 to 400 nm in diameter, being covered with envelopes in which the surface pro ... | 1977 | 409868 |
| a comparison of neurovirulence of vaccinia virus by intrathalamic and/or intracisternal inoculations into cynomolgus monkeys. | 1977 | 409906 | |
| exit sites of uveoscleral flow of aqueous humor in cynomolgus monkey eyes. | 1977 | 410651 | |
| the effect of hemorrhagic shock and resuscitation on regional blood flow in cynomulgus monkeys. | the effect of hemorrhagic hypotension and resuscitation on regional blood flow was studied in the macaca fascicularis monkey. the majority of the splanchnic vasculature demonstrated a profound decrease in flow. following fluid expansion and correction of acidosis, flow increased in these circulations but did not reach control values. exceptions were the small bowel flow which fell only moderately and hepatic arterial flow which did not significantly change. both coronary and adrenal circulations ... | 1977 | 411605 |
| serum estradiol and progesterone during pregnancy and the status of the corpus luteum at delivery in cynomolgus monkeys (macaca fascicularis). | levels of estradiol and progesterone in peripheral serum of seven cynomolgus monkeys (macaca fascicularis) were measured from about the 30th day of pregnancy until parturition. although the pattern of each steroid in circulation differed somewhat from the respective patterns in rhesus monkeys (macaca mulatta), there were basic similarities. on the day of delivery, the corpus luteum was excised and in vitro incubation of dispersed luteal cells was performed. isolated luteal cells produced progest ... | 1977 | 412283 |
| the organization of agonistic relations within two captive groups of java-monkeys (macaca fascicularis). | the paper offers a detailed quantitative descripition of the distribution of agonistic activities over the members of two groups of java-monkeys (macaca fascicularis). these groups lived in captivity and were well-established: i.e. they had an extensive network of genealogical relationships. the study pays special attention to agonistic interactions with three or more participants. its main purpose is an analysis of the way dyadic agonistic relations (e.g. dominance relations) are affected by th ... | 1977 | 412345 |
| alpha1-antitrypsin polymorphism in malaysian macaca irus. | alpha1-antitrypsin types were determined in 200 individual specimens of malaysian macaca irus. we found the pattern b in 76 samples, bc in 116, and c in 8. assuming that these patterns are determined by codominant alleles at one locus, this distribution constitutes a significant (p less than 0.001) deviation from hardy-weinberg equilibrium, because of an excess of bc and low prevalence of c. we found no clear evidence for the presence of alpha1-antitrypsin deficiency comparable to the situation ... | 1977 | 412492 |
| effect of cytochalasin b on conventional drainage of aqueous humor in the cynomolgus monkey. | 1977 | 412695 | |
| comparison of primary rhesus and cynomolgus monkey kidney cell cultures for viral isolation from clinical specimens. | rhesus monkey kidney and cynomolgus monkey kidney cell cultures were compared for viral isolation by using clinical specimens that yielded 203 viral isolates. cynomolgus and rhesus monkey kidney cells were comparable for the isolation of 22 adenoviruses, 12 coxsackieviruses, and one poliovirus. four of 50 echoviruses and seven of ten herpesviruses were detected only in cynomolgus monkey kidney cells. influenza virus was isolated in 84 instances, of which eight were detected only in rhesus and fo ... | 1977 | 195459 |
| cytochalasin b reversibly increases outflow facility in the eye of the cynomolgus monkey. | in cynomolgus monkeys, intracameral infusion of 0.2 to 5.0 mug of cytochalasin b caused an increase in outflow facility, as measured by two-level constant pressure perfusion. cytochalasin b had its full effect in eyes which had undergone surgical disinsertion of the ciliary muscle from the scleral spur, and were therefore insensitive to pilocarpine. the cytochalasin effect was apparent in less than 20 min. and was largely reversible over a few hours. thirty to 50 days after the infusion, facilit ... | 1977 | 401776 |
| interferon induction in cynomolgus and rhesus monkey after repeated doses of a modified polyriboinosinic-polyribocytidylic acid complex. | serum interferon activity was determined in 12 cynomolgus and 12 rhesus monkeys injected intravenously once daily for 10 days with from 0.1 to 6.0 mg of a stabilized polyriboinosinic acid . polyribocytidylic acid complex per kg, composed of polyriboinosinic acid . polyribocytidylic acid, poly-1-lysine, and carboxymethylcellulose [poly(iclc)]. interferon activity was detected 2 h after the first injection, with maximum activity occurring 8 h after the second injection. a period of hyporesponsiven ... | 1977 | 402107 |
| dentofacial changes produced by extraoral forward force in the macaca irus. | eleven macaca irus monkeys with a mixed or a permanent dentition were used in a study of the possible effects of extraoral forward force on the growth of the dentofacial skeleton. an intermittent forward force of 300 gm. per side was applied, and the effects were analyzed by means of model casts, cephalometric radiographs, tetracycline bone marking, microradiographs, and histologic preparations. the results obtained were as follows: 1. an extraoral forward force caused significant changes in the ... | 1977 | 402814 |
| erythroblastosis models. ii. materno-fetal incompatibility in chimpanzee. | erythroblastosis fetalis represents a significant hazard for successful management of pregnancy in man and in marmosets, but not in crab-eating macaques. materno-fetal blood group incompatibility in chimpanzee is described as a contributing factor in the death of an infant. the findings indicate that parental blood groups should be taken into consideration when breeding chimpanzees. | 1977 | 556709 |
| orbital cortical influences on cardiovascular dynamics and myocardial structure in conscious monkeys. | the posterior orbital cortex of the frontal lobes in conscious monkeys was stimulated electrically to study the influence of this structure on cardiovascular hemodynamics and cardiac morphology. stimulating electrodes, cardiac output flow probes, and arterial blood pressure transducers were chronically implanted by aseptic procedures into eight macaca fascicularis monkeys. cardiovascular changes induced by stimulating the orbital cortex included both biphasic and unidirectional alterations in ca ... | 1977 | 403254 |
| experimental pulpitis in immunized monkeys. | bovine serum albumin (bsa) was topically applied to exposed dentin to assess whether inflammatory reactions can be induced in the pulp of monkeys immunized against bsa. four cynomolgus monkeys received repeated injections of bsa emulsified with freund's incomplete adjuvant. pulp challenge was performed by applying bsa in freshly cut dentin cavities prepared on the buccal surface in 34 teeth. in 29 control teeth ovalbumin (ova) was applied. control applications of bsa were also performed in 15 te ... | 1977 | 413185 |
| projections from the primary somatosensory cortex to basal ganglia and thalamus in the monkey. | radioactive amino acids were injected into the postcentral cortex (areas 3, 1 and 2) in 6 monkeys (macaca fascicularis). fibers were traced to the ipsilateral putamen, to olszewski's n. ventralis posterior lateralis pars caudalis, n. ventralis posterior medialis and inferior, to n. pulvinaris oralis, n. suprageniculatus and corpus geniculatum mediale pars magnocellularis. furthermore, there were faint postcentral projections to claustrum, n. caudatus, n. centralis lateralis, n. centrum medianum, ... | 1977 | 413731 |
| metabolism of arylacetic acids. 1. the fate of 1-naphthylacetic acid and its variation with species and dose. | 1. [carboxy-14c]-1-naphthylacetic acid has been administered to man, 6 primate species and 4 other mammalian species and the urinary metabolites examined by radiochromatogram scanning and reverse isotope dilution. animals all received a dose of 100 mg/kg and man received 5 mg, orally. 2. most species excreted at least 60% of the 14c in the urine in 48 h. unchanged acid was a minor (0-17% dose) excretion product in all species except the cynomolgus monkey (35%). 3. in man, in 24 h 95% of 14c was ... | 1977 | 412330 |
| the pathophysiology of induced sah in the spontaneously breathing cynomolgus monkey using different volumes of fresh autogenous blood. | 1977 | 409070 | |
| the enzyme-linked immunosorbent assay and its application to parasitic infections. | the enzyme-linked immunosorbent assay (elisa) was used for the serodiagnosis of four parasitic infections. elisa was performed as a macromethod in polystyrene tubes and/or as a micromethod in polystyrene microplates. conventionally raised pigs were infected orally with different numbers of trichinealla spiralis larvae, and the pigs' sera were tested for antibody to t. spiralis. results were compared with those from sera of uninfected conventionally raised pigs. cynomolgus monkeys were infected o ... | 1977 | 409790 |
| heart mitochondrial metabolism after feeding herring oil to rats and monkeys. | heart mitochondrial oxidation of palmityl coa and pyruvic acid was studied in rats and in the monkey macaca fascicularis to determine the effects of feeding partially hydrogenated herring oil. herring oil glycerides contain cetoleic acid (cis-11-docosenoic) which could have a similar effect to erucic acid (cis-13-docosenoic) in causing a rat cardiomyopathy. the initial rat heart mitochondrial response to dietary cetoleic acid (67% cis, 33% trans) was an in vitro decrease in palmityl coa oxidatio ... | 1977 | 411003 |
| a direct ventral connection between the bed nucleus of the stria terminalis and the amygdaloid complex in the monkey (macaca fascicularis). | a direct ventral connection, between the bed nucleus of the stria terminalis and the amygdaloid complex in the monkey is described. it consists of bundles of extremely fine unmyelinated axons of a median diameter between 0.16 and 0.2 micrometer. the total number of axons is estimated at over 500,000. using observations gained by other authors it is deduced, that the direction of conduction is probably from the bed nucleus of the stria terminalis to the amygdala. other observations in the literat ... | 1977 | 411830 |
| application of freeze-dried monkey erythrocytes to measles viral hemagglutination and hemagglutination-inhibition tests. | erthrocytes collected from monkey species including grivet, rhesus, and cynomolgus monkeys were stabilized by fixation with glutaraldehyde of a low concentration and were freeze-dried in vacuo. these freeze-dried erythrocytes were compared with fresh erythrocytes for measles viral hemagglutination and hemagglutination inhibition and could be used in both tests instead of fresh erythrocytes. they maintained their initial appearance and sensitivity to measles viral hemagglutinins after storage at ... | 1977 | 408375 |
| [changes of the uterine size during pregnancy in cynomolgus monkeys (macaca fascicularis) (author's transl)]. | this paper describes changes in the uterine size during the normal course of pregnancy in cynomolgus monkeys. twenty-four females which had conceived by 3-day individual mating with a male were laparotomized 4,5,6,7,8,9,10,15 and 20 weeks after conception. the width, thickness and length of uterus were measured by a pair of callipers. them, the uterine volume was estimated by the formula, v = 4/3 piab2 (a, b: uterine length x 1/2, uterine width x 1/2). the increase in the uterine width (y) durin ... | 1977 | 404166 |
| metabolism of 15-methyl-prostaglandin f2alpha in the cynomolgus monkey and the human female. | 1977 | 413545 | |
| trabeculo-electropuncture in cynomolgus monkeys (macaca irus). | trabeculo-electropuncture (tep) was performed in one eye of ten cynomolgus monkeys. in five control eyes, the tep probe was inserted into schlemm's canal and withdrawn without causing a spark discharge. in another five control eyes,a scleral window was produced and the canal was opened, but no probe was inserted. the gross facility of outflow was determined prior to the operation and 2, 6, and 18 weeks postoperatively. tep had no longlasting effect on the facility. gonioscopy five months after t ... | 1977 | 404932 |
| absence of self-recognition in a monkey (macaca fascicularis) following prolonged exposure to a mirror. | to date only chimpanzees, orangutans, and humans have been found capable of recognizing themselves in mirrors. in an attempt to provide a more definitive test of the capacity for self-recognition in monkeys. i gave a preadolescent crab-eating macaque 2400 hr of mirror exposure. however, patterns of self-directed behavior never developed and a more explicit test of self-recognition yielded negative results. the data indicate possible differences between great apes and monkeys in self-awareness. | 1977 | 405264 |
| dicentric yields induced by gamma-radiation and chromosome arm number in primates. | to evaluate the effect of the chromosome arm number on the yield of dicentric chromosomes, frequencies of gamma-ray-induced chromosome aberrations were examined with peripheral lymphocytes from three different primate species, saimiri sciureus (arm number, 77), macaca fascicularis (arm number, 83) and nycticebus coucang (arm number, 99). irradiated blood samples were cultured by the same standard technique as that commonly used for human lymphocytes. the yields of dicentrics and dicentrics plus ... | 1977 | 405578 |
| biological effects of cocaine derivative ii: pharmacological evaluation of n-allyl norcocaine in cynomolgus monkeys. | 1977 | 405679 | |
| endotoxic activities of lipopolysaccharides of microorganisms isolated from an infected root canal in macaca cynomolgus. | lipopolysaccharides (lps) prepared from a strain of bacteroides oralis, a strain of fusobacterium necrophorum, and a strain of f. nucleatum, all isolated from an infected root canal in monkey (macaca cynomolgus), were examined for endotoxic activities using primary skin reactions in rabbits and induction of leukocyte chemotaxis in rats. lps of b. oralis showed considerably lower ability to cause skin inflammation than lps of the fusobacteria. however, the leukotactic effect of the lps preparatio ... | 1977 | 405737 |
| subsurface cisterns in the cynomolgus retina. | subsurface cisterns were found in retinal neurons of the cynomolgus monkey. they were located in amacrine, bipolar and ganglion cells and were associated with the rough endoplasmic reticulum. subsurface cisterns were not found in müller cells. the possible functional significance of the subsurface cisterns is discussed. | 1977 | 407003 |
| respiratory pathogens in non-human primates with special reference to corynebacterium ulcerans. | an investigation of 272 non-human primates (75 macacca cynomolgus, 97 macacca mulatta and 100 cercopithecus aethiops) revealed a high incidence of respiratory disease caused by corynebacterium ulcerans, staphylococci, diplococci and streptococci. escherichia coli was also found as a secondary invader. most of the infections occurred during winter in macaca cynomolgus and were caused by corynebacterium ulcerans and diplococcus pneumoniae. the c. ulcerans strains were phage type vi g. a phage typ ... | 1977 | 407395 |
| an overview of the biochemical pharmacology of probucol. | probucol was effective in lowering serum total cholesterol in mice at dietary livels as low as 0.0075%. it was also effective after a single 100 mg/kg i.v. dose in mice. the incorporation of acetate-(14)c into liver lipids of rats and mice was not significantly affected by probucol, although the results, especially in mice, make it impossible to rule out such an effect. cholesterol absorption was estimated in rats using a dual isotope technique. the observed reductions were not statistically sig ... | 1977 | 189154 |
| measurement of hemolytic complement and the third component of complement in nonhuman primates. | complement, determined by hemolytic assay, and the third component of complement (c3), determined by radial immunodiffusion assay, were measured in nine nonhuman primate species. the species studied were the titi (callicebus mollach). the sooty mangabey (cercocebus atys), the thick-tailed galago or bushbaby (galago crassicaudatus panganiensis), the crab-eating monkey (macaca fascicularis), the rhesus monkey (macaca mulatta), the bonnet monkey (macaca radiata), the stumptailed macaque (macaca spe ... | 1977 | 414024 |
| ornithine decarboxylase activity in tooth surface plaque from monkeys (macaca fascicularis) fed pyridoxine, phytate and invert sugar. | 1977 | 414701 | |
| pilocarpine-induced subsensitivity to carbachol and pilocarpine of ciliary muscle in vervet and cynomolgus monkeys. | vervet monkeys were given unilateral treatment for two weeks with one 2% pilocarpine eye drop three times daily between 8 a.m. and 6 p.m. (night interval 14h) and were then subjected to anterior chamber perfusion 20 mug pilocarpine intracamerally caused similar and substantial increases in outflow facility in both eyes. cynomolgus monkeys were unilaterally treated with continuous release of 33 mug/h of pilocarpine for 5-6 days. the facility response to 1 mg/kg pilocarpine iv was small or absent ... | 1977 | 402785 |
| effect of intra-articular corticosteroid injections on primate cartilage. | an attempt was made to ascertain whether intra-articular corticosteroids exert a harmful effect on primate cartilage. the knee joints of 10 macaca irus monkeys were subjected to either one, two, or six injections of 20 mg methyl prednisolone or an equal number of control injections over a 12-week period. minor degenerative changes of many femoral condyles were shown by india ink staining and by a system of histochemical grading. changes in the joints injected with corticosteroid were not signifi ... | 1977 | 402890 |
| pulp changes after anterior mandibular subapical osteotomy in a primate model. | subapical osteotomy of the anterior mandible was carried out on 10 adult macaca irus monkeys with and without open bite. teeth were extracted at 8 weeks, 12 weeks, 24 weeks and 1 year after surgery and the pulps examined histologically. no normal pulps were found. progressive fibrosis and calcification was noted in all teeth. patent pulp blood vessels were found up to 24 weeks after surgery. pulp damage to teeth distal to the osteotomy site was found in 50% of cases. control teeth extracted from ... | 1977 | 403247 |
| metabolism of thromboxane b2 in the cynomolgus monkey. | [5,6,8,9,11,12,14,15-3h8]-thromboxane b2 was injected into the saphenous vein of female cynomolgus monkeys, and blood samples were withdrawn from the contralateral saphenous vein. the compound was eliminated from the circulation with a half-life of about 10 min after an initial rapid disappearance. some more polar products appeared with time, and also small amounts of material less polar than thromboxane b2; however, the dominating compound in all blood samples was unconverted thromboxane b2. ab ... | 1977 | 404670 |
| effects of ischemia on the oxygen diffusion coefficients in the brain cortex (studies on macaca irus). | in this series of experiments changes in oxygen diffusion coefficients were measured in waking primates undergoing focal middle cerebral artery ischemia; ligation of the middle cerebral artery followed by a decrease of the oxygen diffusion coefficient in the areas supplied by that vessel to levels ten to twenty per cent below normal by twenty-five minutes following onset of ischemia. following release and re-perfusion diffusion coefficient gradually increases and reaches a super normal peak valu ... | 1977 | 418626 |
| nursery rearing of infant monkeys (macaca fascicularis) for toxicity studies. | at birth, nine infant male cynomolgus monkeys (macaca fascicularis) weighed an average of 402 g and 16 infant female cynomolgus monkeys weighed an average of 362 g. both female and male infants last 15-20 g by the fourth day after birth. female and male infants showed a growth rate of approximately 4 and 5 g body wt/day, respectively, from 4 to 150 days of age. caloric intake increased from approximately 140 cal/gkg body weight/day in both females and males on the first day after birth to peak v ... | 1977 | 557707 |
| [fluorescence histochemical studies on the monoamine-containing neurons and their pathways in the brain stem of the java monkey (macaca irus)--stereotaxic demonstration of the localization (author's transl)]. | 1977 | 416765 | |
| a ventral tract from the bed nucleus of the stria terminalis to the amygdaloid complex in the monkey (macaca fascicularis): possible pathway in the regulation of ovulation [proceedings]. | characteristics of a ventral tract from the bed nucleus of the stria terminalis (bst) to the amygdaloid complex in the monkey (macaca fascicularis) are described. a system of approximately 200 fiber bundles lying between the bst and baso-lateral part of the amygdaloid complex was identified and postulated to be monosynaptic. the bundles consist of unmyelinated fibers with a median diameter of .16-.20 mcm. no axons could be found with a diameter greater than .55 mcm, and 8% of the fibers had a ... | 1977 | 853388 |
| chromosomal abnormalities in lymphocytes from monkeys poisoned with lead. | cynomolgus monkeys (macaca irus) were given 0, 1.5, 6 or 15 mg of lead acetate 6 days a week for 16 months. another group, also receiving 6 mg, was kept on a low-calcium diet. each experimental group consisted of 2 monkeys. chromosome analysis on cultured lymphocytes was carried out after 3, 10 and 16 months of lead treatment. the frequency of severe abnormalities (dicentrics, rings, translocations and exchanges) was significantly increased only in the group on a low calcium diet, whereas "light ... | 1977 | 917037 |
| brugia timori: experimental infection in some laboratory animals. | experimental infection with brugia timori of 7 jirds (merionesunguiculatus), 4 cats and 2 monkeys (macaca fascicularis) is described. although no microfilariae were detected by examining 20 microliter samples of tail blood of jirds, adult worms were recovered from 6 of the 7 jirds at autopsy 69-141 days following infection. some worms were gravid and microfilariae were found in visceral blood of 2 animals. the adult recovery rate in jirds was 16%; the male to female ratio was 1:3. in cats patent ... | 1977 | 918709 |
| presynaptic dendrites in the cuneate nucleus of the monkey (macaca fascicularis). | presynaptic dendrites (psds) are described in the cuneate nucleus of the monkey. these psds establish dendro-dendritic synapses with dendrites of variable size. they contain small numbers of pleomorphic synaptic vesicles which are clustered together near the presynaptic membrane. such psds have also been observed to be postsynaptic to medium-sized or large axon terminals containing round vesicles. | 1977 | 19604982 |
| sulfated glycoproteins in the acquired pellicle and in plaque from macaca fascicularis demonstrated with labeled sulfate. | 1977 | 405736 | |
| ovulatory cycle characteristics in macaca fascicularis. | a total of 595 menstrual cycles were studied in 28 adult m. fasicularis over a period of five years. ovulations, observed laparoscopically in 138 cycles, occurred on the left ovary 62.6% of the time. no significant effect was noted on cycle length relative to the ovulatory status of the previous cycle or the occurrence of ovulation on the same ovary in consecutive cycles. laparoscopy had no effect on the parameters studied. | 1977 | 864676 |
| factors influencing nursing in macaca fascicularis. | nursing by two mother-infant pairs in a caged colony of macaca fascicularis was monitored at 1-min intervals for 8 h beginning 8:30 a.m. bst, once a week for 3 months in the summer of 1973. nursing occupied about 210 min in 8 daylight hours for the infants at 10 weeks of age, and the time spent nursing decreased at the average rate of 9.4 min per week until the infants were about 6 months old. the time spent nursing by the infants studied here resembles closely the times spent nursing by some ot ... | 1977 | 401755 |
| semen preservation in macaca fascicularis. | semen was collected from adult male macaca fascicularis using a rectal probe for electro-ejaculation. the effect on sperm motility of varying semen extender egg yolk concentration, ph, glycerol concentration, and equilibration times of sperm with glycerol was examined. no significant difference was observed between motilities at extender egg yolk concentrations of 10% to 40%. progressive motility was significantly greater at ph 7.2 and 8.0 than at 5.8, 6.5, and 8.7 (p less than 0.05). glycerol c ... | 1978 | 31513 |
| effect of lh-rh peptide antagonist on serum lh, ovulation and menstrual cycle of crab-eating macaque. | 1978 | 99283 |