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non cell autonomous upregulation of cdkn2 transcription linked to progression of chronic hepatitis c disease.chronic hepatitis c virus infection (c-hc) is associated with higher mortality arising from hepatic and extrahepatic disease. this may be due to accelerated biological aging; however, studies in c-hc have thus far been based solely on telomere length as a biomarker of aging (boa). in this study, we have evaluated cdkn2 locus transcripts as alternative boas in c-hc. our results suggest that c-hc induces non-cell-autonomous senescence and accelerates biological aging. the cdkn2 locus may provide a ...201323931242
burkholderia oklahomensis agglutinin is a canonical two-domain oaa-family lectin: structures, carbohydrate binding and anti-hiv activity.burkholderia oklahomensis eo147 agglutinin (boa) is a 29 kda member of the oscillatoria agardhii agglutinin (oaa) family of lectins. members of the oaa family recognize high-mannose glycans, and, by binding to the hiv envelope glycoprotein 120 (gp120), block the virus from binding to and entering the host cell, thereby inhibiting infection. oaa-family lectins comprise either one or two homologous domains, with a single domain possessing two glycan binding sites. we solved the structure of boa in ...201323480609
an abc pleiotropic drug resistance transporter of fusarium graminearum with a role in crown and root diseases of wheat.fgabc1 (fgsg_04580) is predicted to encode a pleiotropic drug resistance class abc transporter in fusarium graminearum, a globally important pathogen of wheat. deletion mutants of fgabc1 showed reduced virulence towards wheat in crown and root infection assays but were unaltered in infectivity on barley. expression of fgabc1 during head blight and crown rot disease increases during the necrotrophic phases of infection suggestive of a role for fgabc1 in late infection stages in different tissue t ...201323965171
predation of alouatta puruensis by boa constrictor.reports of successful predator attacks on primates are rare. primates from all major radiations are particularly susceptible to raptors, carnivores, and snakes. among new world primates, reports of snake predation are limited to medium- and small-bodied species. here, we report the first documented case of successful predation of an atelid by a snake-an adult female purús red howler monkey, alouatta puruensis, that was subdued by a ca. 2-m-long boa constrictor in an arboreal setting at a height ...201323917944
molecular characterization of trichomonads isolated from animal hosts in the philippines.trichomonads are amitochondrial anaerobic flagellated protists that are either parasites or commensals, generally living in the digestive or genitourinary tract of humans and animals. it has been reported that these protozoa can migrate to other sites in their target host, can adapt to new hosts, and are capable of zoonotic transmission. in this study, 59 trichomonad isolates from different animal hosts in the philippines were identified and characterized. primer sets were designed and were succ ...201323622817
basal blood flow and autoregulation changes in the optic nerve of rhesus monkeys with idiopathic bilateral optic atrophy.to characterize the hemodynamic features and the association with structural damage in the optic nerve head (onh) of idiopathic bilateral optic atrophy (boa) in rhesus macaque monkeys.201323287792
three-dimensional locations of destinations have species-dependent effects on the choice of paths and the gap-bridging performance of arboreal snakes.challenges for moving in arboreal environments include sizable gaps and variable three-dimensional locations between the discrete destinations created by branches. different three-dimensional orientations of the body change the mechanical demands of crossing gaps, especially for elongate animals, but these effects on both the maximal gap distance crossed (gapmax ) and the choice of destinations are poorly understood despite many animals frequently encountering these circumstances. we tested and ...201323281077
vibrational spectroscopic characterization of the phosphate mineral ludlamite (fe,mn,mg)₃(po₄)₂⋅4h₂o - a mineral found in lithium bearing pegmatites.the objective of this work is to analyze ludlamite (fe,mn,mg)(3)(po(4))(2)⋅4h(2)o from boa vista mine, galiléia, brazil and to assess the molecular structure of the mineral. the phosphate mineral ludlamite has been characterized by emp-wds, raman and infrared spectroscopic measurements. the mineral is shown to be a ferrous phosphate with some minor substitution of mg and mn. raman bands at 917 and 950 cm(-1) are assigned to the symmetric stretching mode of hopo(3)(2-) and po(4)(3-) units. raman ...201323257342
development of snake-directed antipredator behavior by wild white-faced capuchin monkeys: i. snake-species discrimination.young animals are known to direct alarm calls at a wider range of species than adults. our field study examined age-related differences in the snake-directed antipredator behavior of infant, juvenile, and adult white-faced capuchin monkeys (cebus capucinus) in terms of alarm calling, looking behavior, and aggressive behavior. in the first experiment, we exposed infant and juvenile white-faced capuchins to realistic-looking inflatable models of their two snake predators, the boa constrictior (boa ...201323229464
immunohistochemical detection of a unique protein within cells of snakes having inclusion body disease, a world-wide disease seen in members of the families boidae and pythonidae.inclusion body disease (ibd) is a worldwide disease in captive boa constrictors (boa constrictor) and occasionally in other snakes of the families boidae and pythonidae. the exact causative agent(s) and pathogenesis are not yet fully understood. currently, diagnosis of ibd is based on the light microscopic identification of eosinophilic intracytoplasmic inclusion bodies in hematoxylin and eosin stained tissues or blood smears. an antigenically unique 68 kda protein was identified within the ibd ...201324340066
secondary prevention of osteoporosis in non-neck of femur fragility fractures: is it value for money? a retrospective, prospective and cross-sectional cohort study.osteoporosis is one of the commonest bone diseases in which bone fragility is increased. over 300,000 patients present to hospitals in the uk with fragility fractures each year, with medical and social care costs - most of which relate to hip fracture care - at around £2 billion. the number of these fractures rises by 2% a year. the 30 days mortality is 10% and 30% at 1 year. the purpose of this study is to review the current practice according to nice and boa guidelines of secondary prevention ...201324289492
near-isogenic lines for measuring phenotypic effects of dimboa-glc methyltransferase activity in maize.three o-methyltransferases (bx10a, b, c) catalyze the conversion of 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one glucoside (dim boa-glc) to 2-hydroxy-4,7-dimethoxy-1,4-benzoxazin-3-one glucoside (hdmboa -glc) in maize (zea mays). variation in benzoxazinoid accumulation and resistance to rhopalosiphum maidis (corn leaf aphid) was attributed to a natural cacta family transposon insertion that inactivates bx10c. whereas maize inbred line b73 has this transposon insertion, line cm l277 does not. to ...201324494232
quality of operation notes in orthopaedic hip arthroplasty surgery: are we complying with british orthopaedic association's guide to good practice?this retrospective audit evaluates the compliance of our operation notes with the british orthopaedic society primary hip arthroplasty 'a guide to good practice' using a 24-data point question (boa 2006). ninety-nine notes reviewed, of which 94% had patient identifiers, the surgical team was documented in 92.5%, post-operative instruction in 97%, and prosthesis stability in 97% of cases. despite high standards, we did not achieve the 100% gold standard. we suggest that increased awareness of the ...201324404704
a fpga embedded web server for remote monitoring and control of smart sensors networks.this article describes the implementation of a web server using an embedded altera nios ii ip core, a general purpose and configurable risc processor which is embedded in a cyclone fpga. the processor uses the μclinux operating system to support a boa web server of dynamic pages using common gateway interface (cgi). the fpga is configured to act like the master node of a network, and also to control and monitor a network of smart sensors or instruments. in order to develop a totally functional s ...201324379047
parthenogenesis in a brazilian rainbow boa (epicrates cenchria cenchria).a 22-year-old captive brazilian rainbow boa (epicrates cenchria cenchria) gave birth to four offspring after being housed with a vasectomized male. sexual reproduction as a result of failed prior vasectomy, recanalization of the vas deferens, or prolonged sperm storage was ruled out using the clinical history, histopathology, and gross necropsy. short tandem repeat (str) dna markers were genotyped in the male, female, and four offspring. none of the offspring possessed a diagnostic str allele pr ...201323086743
species of anastrepha (diptera: tephritidae) captured in a guava orchard (psidium guajava l., myrtaceae) in boa vista, roraima, brazil.the guava fruit (psidium guajava) is among the most strongly affected by fruit flies in brazil. in the brazilian amazon, 11 species of anastrepha have been reported in guava orchards to date. this work aimed to identify the species of anastrepha present in a guava orchard in the municipality of boa vista, determine the species infesting the fruits, and identify any parasitoids present. two mcphail traps with food bait were installed and weekly collections were made between january and december 2 ...201324789406
elevated α-methyl-γ-hydroxy-1,n2-propano-2'-deoxyguanosine levels in urinary samples from individuals exposed to urban air pollution.acetaldehyde and crotonaldehyde are genotoxic aldehydes present in tobacco smoke and vehicle exhaust. the reaction of these aldehydes with 2'-deoxyguanosine in dna produces α-methyl-γ-hydroxy-1,n(2)-propano-2'-deoxyguanosine (1,n(2)-propanodguo). online hplc-tandem mass spectrometry was utilized to accurately quantify 1,n(2)-propanodguo in human urinary samples from 47 residents of são paulo city (sp) and 35 residents of the rural municipality of são joão da boa vista (sjbv) in the state of são ...201324168144
synthesis and hepatoprotective properties of acanthus ilicifolius alkaloid a and its derivatives.acanthus ilicifolius alkaloid a (4-hydroxy-2(3h)benzoxazolone, hboa) is a naturally occurring compound that has been separated from acanthus ilicifolius. previous studies have reported the beneficial effects of hboa on hsc-t6 cells. this study was undertaken in order to synthesize hboa and two of its derivatives, specifically, 4-acetoxy-2(3h)-benzoxazolone (aco-boa) and 3-acetyl-4-acetoxy-2-benzoxazolone (tc-3), and to investigate the hepatoprotective potentials of these three compounds on ccl4- ...201324137268
[juvenile pompe disease: retrospective clinical study].pompe disease or glycogen storage disease type ii is an autosomal recessive disorder due to acid maltase deficiency. it is a rare disease with a prevalence of 1/40.000 in the dutch and african-american populations and 1/46000 in the australian population. there are three forms of clinical presentation (infantile-onset, childhood-onset and adult-onset), although the disease presents as a continuum of clinical phenotypes. enzyme replacement therapy is available in portugal since 2006.201324016645
[images and representations of the female body in brazilian magazines].this documentary, qualitative, descriptive study has the objective to analyze images and representations of the female body and their relation to drug use in the content of articles published in four magazines with national circulation (veja, isto e, boa forma, claúdia). the articles selected were submitted to the technique of content analysis, with three thematic groups identified: the body as an incentive to use drugs; risks to the body resulting from drug use; and the search for the perfect b ...201324015463
comparative sex chromosome genomics in snakes: differentiation, evolutionary strata, and lack of global dosage compensation.snakes exhibit genetic sex determination, with female heterogametic sex chromosomes (zz males, zw females). extensive cytogenetic work has suggested that the level of sex chromosome heteromorphism varies among species, with boidae having entirely homomorphic sex chromosomes, viperidae having completely heteromorphic sex chromosomes, and colubridae showing partial differentiation. here, we take a genomic approach to compare sex chromosome differentiation in these three snake families. we identify ...201324015111
a closer look at the "protopithecus" fossil assemblages: new genus and species from bahia, brazil.the recently extinct large-bodied new world monkey protopithecus brasiliensis lund 1836 was named based on a distal humerus and proximal femur found in the lagoa santa cave system in the southeastern brazilian state of minas gerais. these bones are from an animal about twice the size of the largest extant platyrrhines. one hundred and seventy-five years later, a nearly complete skeleton was discovered in the toca da boa vista caves in the neighboring state of bahia and was allocated to the same ...201323972780
isolation, identification, and characterization of novel arenaviruses, the etiological agents of boid inclusion body disease.boid inclusion body disease (bibd) is a progressive, usually fatal disease of constrictor snakes, characterized by cytoplasmic inclusion bodies (ib) in a wide range of cell types. to identify the causative agent of the disease, we established cell cultures from bibd-positive and -negative boa constrictors. the ib phenotype was maintained in cultured cells of affected animals, and supernatants from these cultures caused the phenotype in cultures originating from bibd-negative snakes. viruses were ...201323926354
conopeptides from cape verde conus crotchii.marine cone snails of the genus conus contain complex peptide toxins in their venom. living in tropical habitats, they usually use the powerful venom for self-defense and prey capture. here, we study conus crotchii venom duct using a peptide mass-matching approach. the c. crotchii was collected on the cape verde archipelago in the boa vista island. the venom was analyzed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms). about 488 molecular masses ...201323783403
molecular mr imaging of neovascular progression in the vx2 tumor with αvβ3-targeted paramagnetic nanoparticles.to assess the dependence of neovascular molecular magnetic resonance (mr) imaging on relaxivity (r1) of αvβ3-targeted paramagnetic perfluorocarbon (pfc) nanoparticles and to delineate the temporal-spatial consistency of angiogenesis assessments for individual animals.201323771914
preliminary genetic analysis supports cave populations as targets for conservation in the endemic endangered puerto rican boa (boidae: epicrates inornatus).the endemic puerto rican boa (epicrates inornatus) has spent 42 years on the endangered species list with little evidence for recovery. one significant impediment to effective conservation planning has been a lack of knowledge of the distribution of genetic variability in the species. it has previously been suggested that boas might best be protected around caves that harbor large populations of bats. prior study has found puerto rican boas at relatively high densities in and around bat caves, w ...201323691110
implementing the national hip fracture database: an audit of care.hip fractures are common injuries in the elderly, with significant associated morbidity and mortality rates. the national hip fracture database (nhfd) was implemented to audit care according to national standards thus improving its clinical and cost-effectiveness.201323680283
potential adverse health effects of persistent organic pollutants on sea turtles: evidences from a cross-sectional study on cape verde loggerhead sea turtles.the cape verde nesting population of loggerhead sea turtles (caretta caretta) is the third largest population of this species in the world. for conservation purposes, it is essential to determine how these reptiles respond to different types of anthropogenic contaminants. we evaluated the presence of organochlorine pesticides (ocps), polychlorinated biphenyls (pcbs), and polycyclic aromatic hydrocarbons (pahs) in the plasma of adult nesting loggerheads from boa vista island, cape verde, and stud ...201323665416
snakes mimic earthworms: propulsion using rectilinear travelling waves.in rectilinear locomotion, snakes propel themselves using unidirectional travelling waves of muscular contraction, in a style similar to earthworms. in this combined experimental and theoretical study, we film rectilinear locomotion of three species of snakes, including red-tailed boa constrictors, dumeril's boas and gaboon vipers. the kinematics of a snake's extension-contraction travelling wave are characterized by wave frequency, amplitude and speed. we find wave frequency increases with incr ...201323635494
beyond the born-oppenheimer approximation: a treatment of electronic flux density in electronically adiabatic molecular processes.intuition suggests that a molecular system in the electronic ground state φ0 should exhibit an electronic flux density (efd) in response to the motion of its nuclei. if that state is described by the born-oppenheimer approximation (boa), however, a straightforward calculation of the efd yields zero, since the electrons are in a stationary state, regardless of the state of the nuclear motion. here an alternative pathway to a nonzero efd from a knowledge of only the boa ground-state wave function ...201323634652
pegylated filgrastim is comparable with filgrastim as support for commonly used chemotherapy regimens: a multicenter, randomized, crossover phase 3 study.the purpose of this study was to compare the efficacy and safety of a single subcutaneous injection of pegylated filgrastim with daily filgrastim as a prophylaxis for neutropenia induced by commonly used chemotherapy regimens. fifteen centers enrolled 337 chemotherapy-naive cancer patients with normal bone marrow function. all patients randomized into aob and boa arms received two cycles of chemotherapy. patients received a single dose of pegylated filgrastim 100 µg/kg in cycle 1 (aob) or cycle ...201323571496
diagnosis and treatment of a pharyngeal squamous cell carcinoma in a madagascar ground boa (boa madagascariensis).a 15-yr-old female madagascar ground boa (boa madagascariensis) presented with a history of anorexia, wheezing, and occasional open-mouth breathing. on oral examination, a firm, caseous mass was noted in the right caudoventral pharyngeal region, which was confirmed as a carcinoma on incisional biopsy. advanced imaging (computed tomography and magnetic resonance imaging) was performed to evaluate local tumor invasion and to plan for palliative radiation therapy. however, following the second trea ...201323505715
computation of the electronic flux density in the born-oppenheimer approximation.a molecule in the electronic ground state described in the born–oppenheimer approximation (boa) by the wave function ψbo = φ0χ0 (where φ0 is the time-independent electronic energy eigenfunction and χ0 is a time-dependent nuclear wave packet) exhibits a nonzero nuclear flux density, whereas it always displays zero electronic flux density (efd), because the electrons are in a stationary state. a hierarchical approach to the computation of the efd within the context of the boa, which utilizes only ...201323425513
benzoxazinoids in rye allelopathy - from discovery to application in sustainable weed control and organic farming.the allelopathic potency of rye (secale cereale l.) is due mainly to the presence of phytotoxic benzoxazinones-compounds whose biosynthesis is developmentally regulated, with the highest accumulation in young tissue and a dependency on cultivar and environmental influences. benzoxazinones can be released from residues of greenhouse-grown rye at levels between 12 and 20 kg/ha, with lower amounts exuded by living plants. in soil, benzoxazinones are subject to a cascade of transformation reactions, ...201323385365
intracoelomic anaplastic sarcoma in an intersex madagascar tree boa (sanzinia madagascariensis).an adult madagascar tree boa (sanzinia madagascariensis) underwent coeliotomy for investigation of a coelomic mass. at surgery, a large mass originating from the peri-pancreatic adipose tissue and involving the gall bladder was removed. the snake did not recover from general anesthesia. a complete postmortem was performed, and samples were submitted to the university of glasgow for histopathology. on histological examination, the mass was composed of adipose tissue infiltrated with a poorly dema ...201323345276
[socioeconomic and demographic indicators and nutritional status of children in a rural land settlement in rio de janeiro].this study evaluated socioeconomic indicators and nutritional status in 201 children and adolescents in a rural land settlement in são josé da boa morte, rio de janeiro. nutritional deficit was defined as a value below -2 z score for the reference median from the national center for health statistics (nchs) for weight-for-age (w/a) and stature-for-age (s/a) for children under five years of age and weight-for-stature (w/s) and s/a for children from 5.0 to 9.9 years. for adolescents, the study use ...201311784907
stillbirth rates and folic acid and zinc status in low-socioeconomic pregnant women of brazilian amazon.twenty-five women in their first trimester and 25 women in their third trimester of pregnancy were randomly chosen from the slum areas of eight towns in the brazilian amazon (manaus, sao luis, boa vista, porto velho, sao gabriel, santarem, tefe, and benjamin constant). blood samples were removed from the subjects for folic acid and zinc analyses, and the women were asked questions about whether they had suffered from complications during previous pregnancies. it was found that the stillbirth rat ...20138485329
[the health status of yanomámi indians: diagnosis from the casa do indio, boa vista, roraima, 1987 - 1989].the change in the morbidity profile of the yanomámi indians admitted to the casa do indio, at boa vista, roraima, from january 1987 to august 1989, is reported. the most frequent diseases observed in 495 patients were malaria, acute respiratory infections, tuberculosis, severe under nutrition, and sexually transmitted diseases. malaria was the main cause of death of 114 indians throughout the period. a striking increase in hospital admissions was noted in the population from the villages which w ...201315798859
wet- and dry-season steroid hormone profiles and stress reactivity of an insular dwarf snake, the hog island boa (boa constrictor imperator).field endocrine studies providing new comparisons for inference into the evolutionary and ecological factors shaping organismal physiology are important, often yielding novel physiological insights. here, we explored factors associated with the sex steroid hormone concentrations and adrenocortical response to capture stress in hog island boas (boa constrictor imperator) in the cayos cochinos archipelago of honduras to generate comparative field hormone data from a tropical reptile and test the i ...201424769701
immediate care of open extremity fractures: where can we improve?clear guidelines are set by the british orthopaedic association (boa) and british association of plastic, reconstructive and aesthetic surgeons (bapras) on the preoperative management of open fractures. this as well as the clinical consequences of poor management of open fractures means the patient workup for surgery is important as well as the timing of surgery. experience suggests few patients are managed 100% as per the guidelines and we look to test this hypothesis. a retrospective analysis ...201424672795
consenting operative orthopaedic trauma patients: challenges and solutions.guidelines exist to obtain informed consent before any operative procedure. we completed an audit cycle starting with retrospective review of 50 orthopaedic trauma procedures (phase 1 over three months to determine the quality of consenting documentation). the results were conveyed and adequate training of the staff was arranged according to guidelines from boa, doh, and gmc. compliance in filling consent forms was then prospectively assessed on 50 consecutive trauma surgeries over further three ...201424653843
reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old.reliable and valid biomarkers of ageing (boa) are needed to understand mechanisms, test interventions and predict the timing of adverse health events associated with ageing. since increased reactive oxygen species (ros) production and mitochondrial dysfunction are consequences of cellular senescence and may contribute causally to the ageing of organisms, we focused on these parameters as candidate boa. superoxide levels, mitochondrial mass and mitochondrial membrane potential in human peripheral ...201424614678
cytogenetic and morphometric analysis in the species astyanax altiparanae garutti & britski, 2000 (teleostei, characidae) from the iguatemi river basin, brazil.the genus astyanax is relatively common and encompasses various similar taxa forming a highly complex group that is difficult to precisely delimit. the present study aims to analyze cytogenetically and morphologically specimens of a. altiparanae belonging to distinct populations of the iguatemi river basin, mato grosso do sul state, brazil, for a better understanding of the evolutionary processes in this fish group. this study analysed 32 specimens of astyanax altiparanae from iguatemi river bas ...201425403073
stone anvil damage by wild bearded capuchins (sapajus libidinosus) during pounding tool use: a field experiment.we recorded the damage that wild bearded capuchin monkeys (sapajus libidinosus) caused to a sandstone anvil during pounding stone tool use, in an experimental setting. the anvil was undamaged when set up at the fazenda boa vista (fbv) field laboratory in piauí, brazil, and subsequently the monkeys indirectly created a series of pits and destroyed the anvil surface by cracking palm nuts on it. we measured the size and rate of pit formation, and recorded when adult and immature monkeys removed loo ...201425372879
spectral analysis of two coupled diatomic rotor molecules.in a previous article the theory of frame transformation relation between body oriented angular (boa) states and lab weakly coupled states (lwc) was developed to investigate simple rotor-rotor interactions. by analyzing the quantum spectrum for two coupled diatomic molecules and comparing it with spectrum and probability distribution of simple models, evidence was found that, as we move from a lwc state to a strongly coupled state, a single rotor emerges in the strong limit. in the low coupling, ...201425353181
effect of biometric variables on two-dimensional echocardiographic measurements in the red-tailed boa (boa constrictor constrictor).the effects of body biometrics on cardiac measurements and description of cardiac anatomy were performed in red-tailed boas (boa constrictor constrictor) (n = 29) using real-time b-mode ultrasonography. statistical comparison of measured cardiac metrics according to sex and body measurements demonstrated no significant difference between sexes but a highly significant linear increase between body length and mass and all cardiac metrics.201425314841
ecology of the sand boa, eryx jayakari in riyadh region of saudi arabia.the ecology, feeding habits and sexual dimorphism in arabian sand boa, eryx jayakari from the central region of saudi arabia, were studied. in this study the e. jayakari was recorded for the first time from several sites. significant differences were noted in total length of body and tail, and body diameter of male and female. the females were of larger size. the mean number of the dorsal body scales, ventrals and subcaudal for both sexes were not significantly different. the mean number of the ...201425313272
subsistence hunting of cuniculus paca in the middle of the solimões river, amazonas, brazil.ungulates, large primates and caviomorfs are cited by amazonian hunters as preferred species. in this research, paca (cuniculus paca) hunting was investigated in relation to water levels and the lunar cycle. in eight years of monitoring in the amanã sustainable development reserve, the killing of 625 pacas was registered in five monitored communities. paca hunting took place mainly at night and the most commonly used method is "spotlighting". a positive correlation between the number of pacas ki ...201425296203
prevalence of neutralising antibodies against adenoviruses in lizards and snakes.adenoviruses (advs) are relatively common in lizards and snakes, and several genetically distinct advs have been isolated in cell culture. the aims of this study were to examine serological relationships among lizard and snake advs and to determine the frequency of adv infections in these species. isolates from a boa constrictor (boa constrictor), a corn snake (pantherophis gutattus) and a central bearded dragon (pogona vitticeps), and two isolates from helodermatid lizards (heloderma horridum a ...201425163614
anti-inflammatory potential of zootherapeutics derived from animals used in brazilian traditional medicine.animals are used for the treatment of diseases caused by inflammatory processes, although few studies evaluate their potential for these purposes.201425026349
experimental infection of boa constrictor with an orthoreovirus isolated from a snake with inclusion body disease.orthoreoviruses have been associated with disease in reptiles, but have not previously been isolated from snakes with inclusion body disease (ibd). an orthoreovirus was isolated from a boa constrictor diagnosed with ibd and then used to conduct a transmission study to determine the clinical importance of this virus. for the transmission study, 10 juvenile boas were experimentally infected with the isolated orthoreovirus and compared to 5 sham-infected control animals. orthoreovirus was reisolate ...201425000715
[better management of osteoarthritis, boa]. 201424946500
the behavioural outcomes of anxiety scale (boa): a preliminary validation in stroke survivors.to determine the psychometric properties of an observational scale of anxiety.201424837000
an overview of the south american fossil squamates.the evolution of squamates in south america is the result of the complex geological and paleoclimatic history of this part of the world. the incomplete and episodic fossil record allows us to know only a small part of this evolution. most mesozoic squamate remains come from the patagonian region, but remarkable specimens have also been recovered from brazil. both major squamate clades (iguania and scleroglossa) are present in the south american mesozoic. remains of mesozoic snakes are common and ...201424482358
adder bite on eyelid along with retained intraorbital fangs.snake bite to the eye is a rare event. most cases reported in the literature are due to boa constrictor bites. this is a rare case of snake bite from a common adder (vipera berus) to the ocular adnexa along with a retained intraorbital tooth.201424195742
toward a tree-of-life for the boas and pythons: multilocus species-level phylogeny with unprecedented taxon sampling.snakes in the families boidae and pythonidae constitute some of the most spectacular reptiles and comprise an enormous diversity of morphology, behavior, and ecology. while many species of boas and pythons are familiar, taxonomy and evolutionary relationships within these families remain contentious and fluid. a major effort in evolutionary and conservation biology is to assemble a comprehensive tree-of-life, or a macro-scale phylogenetic hypothesis, for all known life on earth. no previously pu ...201424315866
osteomyelitis caused by salmonella enterica serovar derby in boa constrictor.after demonstrating chronic weight loss, prostration, and muscle flaccidness, a captive-bred 9-mo-old boa constrictor (boa constrictor constrictor) died and was submitted for necropsy. along the spinal column there were multiple, yellowish white, macroscopic nodules of 1-5 mm in diameter in the ventral side of the vertebral body and in the intervertebral spaces. severe multifocal necrotizing osteomyelitis associated with granulomatous inflammation was the main histologic finding in the vertebral ...201425314834
identification and quantification of benzimidazole resistance polymorphisms in haemonchus contortus isolated in northeastern brazil.haemonchus contortus is the most prevalent nematode in brazil. the objective of this study was to select 6 populations of h. contortus of known or suspected benzimidazole resistance status and characterize these using quantitative real-time polymerase chain reaction (qpcr) for single nucleotide polymorphisms (snps) f200y, f167y and e198a in the β-tubulin isotype 1 gene. qpcr was performed using dna from a pool of 10 adult male h. contortus from a single animal per farm. faecal egg count reductio ...201424295955
new tick records from the state of rondônia, western amazon, brazil.from 2005 to 2012, ticks were collected from different hosts at different localities of the state of rondônia. the following 16 ixodid tick species were identified: ixodes fuscipes, amblyomma auricularium, amblyomma coelebs, amblyomma dubitatum, amblyomma geayi, amblyomma humerale, amblyomma latepunctatum, amblyomma longirostre, amblyomma naponense, amblyomma nodosum, amblyomma oblongoguttatum, amblyomma ovale, amblyomma romitii, amblyomma rotundatum, amblyomma scalpturatum, and amblyomma varium ...201423975565
computed tomography-guided bone biopsies for evaluation of proliferative vertebral lesions in two boa constrictors (boa constrictor imperator).two boa constrictors (boa constrictor imperator) presented with paresis of the trunk originating cranial to the cloaca. radiographs were consistent with proliferative bone lesions involving several vertebrae. computed tomography (ct) demonstrated the presence of lytic/expansile lesions. computed tomography-guided biopsies of the lesions were performed without complications. histology was consistent with bacterial osteomyelitis and osteoarthritis. gram-negative bacteria (salmonella sp. and pseudo ...201425632696
ultrasound imaging of the anterior section of the eye of five different snake species.nineteen clinically normal snakes: six ball pythons (python regius), six burmese pythons (python bivittatus), one children's python (antaresia childreni), four amazon tree boas (corallus hortulanus), and two malagasy ground boas (acrantophis madagascariensis) were subjected to ultrasound imaging with 21 mhz (ball python) and 50 mhz (ball python, burmese python, children's python, amazon tree boa, malagasy ground boa) transducers in order to measure the different structures of the anterior segmen ...201425547871
x-ray fluorescence and gamma-ray spectrometry combined with multivariate analysis for topographic studies in agricultural soil.physical and chemical properties of soils play a major role in the evaluation of different geochemical signature, soil quality, discrimination of land use type, soil provenance and soil degradation. the objectives of the present study are the soil elemental characterization and soil differentiation in topographic sequence and depth, using energy dispersive x-ray fluorescence (edxrf) as well as gamma-ray spectrometry data combined with principal component analysis (pca). the study area is an agri ...201425464179
replication of boid inclusion body disease-associated arenaviruses is temperature sensitive in both boid and mammalian cells.boid inclusion body disease (bidb) is a fatal disease of boid snakes, the etiology of which has only recently been revealed following the identification of several novel arenaviruses in diseased snakes. bibd-associated arenaviruses (bibdav) are genetically divergent from the classical old and new world arenaviruses and also differ substantially from each other. even though there is convincing evidence that bibdav are indeed the etiological agent of bibd, the bibdav reservoir hosts--if any exist ...201425378485
undesirable consequences of insecticide resistance following aedes aegypti control activities due to a dengue outbreak.during a dengue outbreak with co-circulation of denv-1 and -2 in the city of boa vista, one patient was diagnosed with denv-4, a serotype supposed absent from brazil for almost 30 years. the re-emergence of denv-4 triggered the intensification of mechanical and chemical aedes aegypti control activities in order to reduce vector density and avoid denv-4 dissemination throughout the country.201424676277
challenges encountered using standard vector control measures for dengue in boa vista, brazil.in 2010, dengue virus (denv) serotype-4 was detected during a dengue outbreak in the amazonian city of boa vista. at that time brazil was already endemic for denv-1, denv-2 and denv-3. this was the first time denv-4 was observed in the country after it was initially detected and eliminated in 1981.201425378760
ocular surface squamous neoplasia in hiv-positive and hiv-negative patients and response to 5-fluorouracil in angola.ocular surface squamous neoplasia (ossn) is becoming increasingly prevalent and aggressive in sub-saharan africa. it is a phenomenon linked with human immunodeficiency virus (hiv) infection, although association rates in angola are currently unknown. a topical treatment that is effective in hiv-positive and hiv-negative individuals may be preferable to surgery in some contexts. we aimed to estimate the proportion of ossn associated with hiv in angola and to report on the success of topical 5-flu ...201425506205
anti-inflammatory activity of animal oils from the peruvian amazon.animal oils and fats from the fishes electrophorus electricus and potamotrygon motoro, the reptiles boa constrictor, chelonoidis denticulata (geochelone denticulata) and melanosuchus niger and the riverine dolphin inia geoffrensis are used as anti-inflammatory agents in the peruvian amazon. the aim of the study was to assess the topic anti-inflammatory effect of the oils/fats as well as to evaluate its antimicrobial activity and fatty acid composition.201425150527
abutilon theophrasti's defense against the allelochemical benzoxazolin-2(3h)-one: support by actinomucor elegans.abutilon theophrasti medik., previously found to be rather insensitive to benzoxazinoid containing rye mulch and the allelochemical benzoxazolin-2(3h)-one (boa), can be associated with the zygomycete actinomucor elegans, whereby the fungus colonizes the root relatively superficially and mainly in the maturation zone. the fungus mitigates necrosis of the cotyledons when seedlings are incubated with 2 mm boa, in contrast to those that lack the fungus. in liquid cultures of the fungus, tryptophan w ...201425432667
the influence of industrial and agricultural waste on water quality in the água boa stream (dourados, mato grosso do sul, brazil).water quality monitoring is used to determine the impact of human activities on the environment. we evaluated water quality in the água boa stream, located within the municipality of dourados, state of mato grosso do sul, brazil, by analyzing physico-chemical, chemical, and microbiological parameters, as well as chlorophyll concentrations. five sets of water samples were collected between december 2012 and november 2013 from three locations within the stream. the results showed the presence of e ...201526088756
prevalence and characterization of chlamydia dna in zoo animals in japan.because many people visit zoos, prevention of zoonoses is important from the standpoint of public health. this study examined the prevalence of chlamydia among zoo animals in japan by pcr and characterized these bacteria by performing phylogenetic analyses of the sequences of the variable domain (vd) 2 and vd4 regions of the ompa gene, which encodes the chlamydia major outer membrane protein. fecal samples were collected from 1150 zoo animals in five zoos and examined for chlamydia dna. chlamydi ...201526215334
effects of baseplates of orthodontic appliances with in situ generated silver nanoparticles on cariogenic bacteria: a randomized, double-blind cross-over clinical trial.polymethyl-methacrylate (pmma) is commonly used primarily for baseplates of orthodontic appliances (boa). the activities of cariogenic bacteria in biofilm on these surfaces may contribute to dental caries, gingival inflammation and periodontal disease. the pmma incorporated with nanoparticles of silver (nanoag-i-pmma) and nanoag in situ in pmma (nanoag-is-pmma) have been shown to control the growth of cariogenic bacteria, but clinical trial of anti-cariogenic application of these novel materials ...201526067732
quantitative studies on motoneurons. ii. spatial and dimensional organization of hypoglossal motoneurons in the boa constrictor, constrictor constrictor. 20154415432
parsonage-turner syndrome.to describe the clinical, electrophysiological and imaging findings from parsonage-turner syndrome and evaluate the results from conservative treatment.201526229940
uranium isotopes in groundwater occurring at amazonas state, brazil.this paper reports the behavior of the dissolved u-isotopes (238)u and (234)u in groundwater providing from 15 cities in amazonas state, brazil. the isotope dilution technique accompanied by alpha spectrometry were utilized for acquiring the u content and (234)u/(238)u activity ratio (ar) data, 0.01-1.4µgl(-1) and 1.0-3.5, respectively. these results suggest that the water is circulating in a reducing environment and leaching strata containing minerals with low uranium concentration. a tendency ...201525528017
gold-oxoborate nanocomposites and their biomedical applications.a novel inorganic nanocomposite material, called boa, which has the form of small building blocks composed of gold nanoparticles embedded in a polyoxoborate matrix, is presented. it is demonstrated that cotton wool decorated with the boa nanocomposite displays strong antibacterial activity toward both gram-positive and -negative bacteria strains. importantly, the modified cotton does not release any toxic substances, and the bacteria are killed upon contact with the fibers coated with the boa. t ...201525625378
cooperative rescue and predator fatality involving a group-living strepsirrhine, coquerel's sifaka (propithecus coquereli), and a madagascar ground boa (acrantophis madagascariensis).the interactions between primates and their snake predators are of interest because snakes have influenced the evolution of primate visual systems and predation has driven the evolution of primate behaviour, including group living. however, there are few accounts of primate-snake interactions in the wild. we report an incident from northwest madagascar in which a large female madagascar ground boa (acrantophis madagascariensis) captured an adult female coquerel's sifaka (propithecus coquereli); ...201525737055
the audiological journey and early outcomes of twelve infants with auditory neuropathy spectrum disorder from birth to two years of age.to describe the audiological journey of a group of infants with auditory neuropathy spectrum disorder (ansd) following the fitting of hearing aids, and to investigate the potential benefits of including cortical auditory-evoked potentials (caeps) and a measure of functional auditory behaviour during early audiological management.201525812580
detection of arenavirus in a peripheral odontogenic fibromyxoma in a red tail boa (boa constrictor constrictor) with inclusion body disease.a captive bred red tail boa (boa constrictor constrictor) was presented with a large intraoral mass originating from the buccal gingiva, attached to the right dentary teeth row. based on the clinical features and histological examination, the diagnosis of a peripheral odontogenic fibromyxoma was made. sections of liver biopsies and circulating lymphocytes contained relatively few eosinophilic intracytoplasmic inclusion bodies, indistinguishable from those observed in inclusion body disease-affec ...201525776548
preoperative predictive factors for intensive care unit admission after pulmonary resection.to determine whether the use of a set of preoperative variables can predict the need for postoperative icu admission.201525750672
cervical cancer screening coverage in a high-incidence region.objective to analyze the coverage of a cervical cancer screening program in a city with a high incidence of the disease in addition to the factors associated with non-adherence to the current preventive program. methods a cross-sectional study based on household surveys was conducted. the sample was composed of women between 25 and 59 years of age of the city of boa vista, rr, northern brazil who were covered by the cervical cancer screening program. the cluster sampling method was used. the dep ...201525741655
bilaterally symmetrical oral amelanotic melanoma in a boa constrictor (boa constrictor constrictor).a 17-yr-old boa constrictor (boa constrictor constrictor) presented initially with diffuse gingival swelling, loose teeth, and loss of body condition. examination under anesthesia revealed two firm pink masses within the oral cavity. the largest mass was removed for biopsy. histopathology and melan-a-positive immunohistochemistry labeling confirmed a diagnosis of amelanotic melanoma. secondary stomatitis was treated with antibiotics to improve quality of life, but the snake's condition deteriora ...201526352976
from guidelines to standards of care for open tibial fractures.the standards for the management of open fractures of the lower limb published by the british association of plastic, reconstructive and aesthetic surgeons (bapras) and british orthopaedic association (boa) were introduced to improve the treatment received by patients after open injury to the lower limb. these standards were released after bapras/boa published guidelines for the management of open tibial fractures.201526274742
distinguishing the effects of bond-length alternation versus bond-order alternation on the nonlinear optical properties of π-conjugated chromophores.understanding the relationships between the molecular nonlinear optical (nlo) properties and the bond-length alternation (bla) or π-bond-order alternation (boa) along the molecular backbone of linear π-conjugated systems has proven widely useful in the development of nlo organic chromophores and materials. here, we examine model polymethines to elucidate the reliability of these relationships. while bla is solely a measure of molecular geometric structure, boa includes information pertaining to ...201526266585
molecular cloning and characterization of satellite dna sequences from constitutive heterochromatin of the habu snake (protobothrops flavoviridis, viperidae) and the burmese python (python bivittatus, pythonidae).highly repetitive dna sequences of the centromeric heterochromatin provide valuable molecular cytogenetic markers for the investigation of genomic compartmentalization in the macrochromosomes and microchromosomes of sauropsids. here, the relationship between centromeric heterochromatin and karyotype evolution was examined using cloned repetitive dna sequences from two snake species, the habu snake (protobothrops flavoviridis, crotalinae, viperidae) and burmese python (python bivittatus, pythonid ...201526205503
snake constriction rapidly induces circulatory arrest in rats.as legless predators, snakes are unique in their ability to immobilize and kill their prey through the process of constriction, and yet how this pressure incapacitates and ultimately kills the prey remains unknown. in this study, we examined the cardiovascular function of anesthetized rats before, during and after being constricted by boas (boa constrictor) to examine the effect of constriction on the prey's circulatory function. the results demonstrate that within 6 s of being constricted, peri ...201526202779
bess/boa patient care pathways: traumatic anterior shoulder instability. 201527582981
facultative thermogenesis during brooding is not the norm among pythons.facultative thermogenesis is often attributed to pythons in general despite limited comparative data available for the family. while all species within pythonidae brood their eggs, only two species are known to produce heat to enhance embryonic thermal regulation. by contrast, a few python species have been reported to have insignificant thermogenic capabilities. to provide insight into potential phylogenetic, morphological, and ecological factors influencing thermogenic capability among pythons ...201526113382
identification of snake arenaviruses in live boas and pythons in a zoo in germany.recent studies have described the detection and characterisation of new, snake specific arenaviruses in boas and pythons with inclusion body disease (ibd). the objective of this study was to detect arenaviral rna in live snakes and to determine if these were associated with ibd in all cases. samples for arenavirus detection in live animals were compared. detected viruses were compared in order to understand their genetic variability.201526109078
beta oscillations and reward processing: coupling oscillatory activity and hemodynamic responses.diverse cortical and subcortical regions are synergically engaged during reward processing. previous studies using time-frequency decomposition of electroencephalography (eeg) data have revealed an increase of mid-frontal beta oscillatory activity (boa) after reward delivery, which could be a potential mechanism in the coordination of the different areas engaged during reward processing. in order to evaluate this hypothesis, twenty subjects performed a monetary gambling paradigm in two separate ...201526070260
origins and processes of groundwater salinization in the urban coastal aquifers of recife (pernambuco, brazil): a multi-isotope approach.in the coastal multilayer aquifer system of a highly urbanized southern city (recife, brazil), where groundwaters are affected by salinization, a multi-isotope approach (sr, b, o, h) was used to investigate the sources and processes of salinization. the high diversity of the geological bodies, built since the atlantic opening during the cretaceous, highly constrains the heterogeneity of the groundwater chemistry, e.g. sr isotope ratios, and needs to be integrated to explain the salinization proc ...201526063126
risk chart for future mortality and ischaemic events following peripheral bypass surgery.a prediction model to identify determinants and quantify the risk of future ischaemic events in patients with peripheral arterial disease (pad) provides a personal risk profile to offer individualized patient care. a risk chart was derived and validated in patients who received infrainguinal bypass surgery.201525981699
wild bearded capuchin monkeys crack nuts dexterously.dexterous tool use has been crucial in the evolution of hominid percussive technology. according to newell, "dexterity" is the ability of an organism to make goal-directed corrections in movements to optimize effort. dexterous movements are smooth and effective and accomplish the same goal with less energy than less dexterous movements. dexterity develops during the later phases of refining a motor skill as the actor becomes sensitive to the outcome of the preceding movement, or to its modulatio ...201525936553
the use of secure anonymised data linkage to determine changes in healthcare utilisation following severe open tibial fractures.severe open fractures of the lower limbs are complex injuries requiring expert multidisciplinary management in appropriate orthoplastic centres. this study aimed to assess the impact of open fractures on healthcare utilisation and test the null hypotheses that there is no difference in healthcare utilisation between the year before and year after injury, and that there is no difference in healthcare utilisation in the year post-injury between patients admitted directly to an orthoplastic centre ...201525916805
environmental dna (edna) sampling improves occurrence and detection estimates of invasive burmese pythons.environmental dna (edna) methods are used to detect dna that is shed into the aquatic environment by cryptic or low density species. applied in edna studies, occupancy models can be used to estimate occurrence and detection probabilities and thereby account for imperfect detection. however, occupancy terminology has been applied inconsistently in edna studies, and many have calculated occurrence probabilities while not considering the effects of imperfect detection. low detection of invasive gia ...201525874630
genetic divergence and diversity in the mona and virgin islands boas, chilabothrus monensis (epicrates monensis) (serpentes: boidae), west indian snakes of special conservation concern.habitat fragmentation reduces the extent and connectivity of suitable habitats, and can lead to changes in population genetic structure. limited gene flow among isolated demes can result in increased genetic divergence among populations, and decreased genetic diversity within demes. we assessed patterns of genetic variation in the caribbean boa chilabothrus monensis (epicrates monensis) using two mitochondrial and seven nuclear markers, and relying on the largest number of specimens of these sna ...201525837733
benzoxazolin-2(3h)-one inhibits soybean growth and alters the monomeric composition of lignin.the effects of the allelochemical benzoxazolin-2-(3h)-one (boa) were evaluated on growth, lignin content and its monomers p-hydroxyphenyl (h), guaiacyl (g) and syringyl (s) in roots, stems and leaves of soybean. boa decreased the lengths and fresh weights of roots and stems, and the fresh weights and areas of leaves. reductions in the growth were accompanied by enhanced lignin content in all tissues. in roots, the allelochemical increased the content of h, g and s monomers as well as the overall ...201525826260
genetic diversity and structure in natural populations of maytenus truncata reiss, 1861, a medicinal plant vulnerable to extractivism in bahia state, brazil.maytenus truncata (celastraceae) is a plant species widely used in the treatment of ulcers and tumors. despite the intensive harvest of native specimens in the state of bahia, northeastern brazil, there is no information about the genetic variability or structure of this species. therefore, the goal of this study was to estimate the genetic diversity and population structure of m. truncata based on inter simple sequence repeat (issr) molecular markers. the samples comprised specimens from jequié ...201526782471
effect of seasonal flooding cycle on litterfall production in alluvial rainforest on the middle xingu river (amazon basin, brazil).the assumption for this study was that litterfall in floodplain environments of the middle xingu river follows a pattern of seasonal variation. according to this view, litterfall production (total and fractions) was estimated in four alluvial rainforest sites on the middle xingu river over an annual cycle, and examined the effect of seasonal flooding cycle. the sites included two marginal flooded forests of insular lakes (ilha grande and pimentel) and two flooded forests on the banks of the xing ...201526691098
why arboreal snakes should not be cylindrical: body shape, incline and surface roughness have interactive effects on locomotion.depending on animal size, shape, body plan and behaviour, variation in surface structure can affect the speed and ease of locomotion. the slope of branches and the roughness of bark both vary considerably, but their combined effects on the locomotion of arboreal animals are poorly understood. we used artificial branches with five inclines and five peg heights (≤40 mm) to test for interactive effects on the locomotion of three snake species with different body shapes. unlike boa constrictors (boa ...201526677261
quality of recovery after anesthesia: validation of the portuguese version of the 'quality of recovery 15' questionnaire.the "quality of recovery 15" questionnaire is used for the study of quality recovery after anesthesia. the aim of this study was to validate the portuguese version of "quality of recovery 15" questionnaire.201526667859
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