Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| schistosome infections in humans: perspectives and recent findings. nih conference. | approximately 200 million persons are infected with schistosomes. of those infected, a small proportion develop serious chronic disease, usually after years of intensive exposure and infection. schistosoma mansoni and schistosoma japonicum reside in the mesenteric veins and produce liver fibrosis, which results in portal hypertension and bleeding esophageal varices but little hepatocellular dysfunction. schistosoma haematobium resides primarily in the pelvic veins and produces mass lesions in th ... | 1982 | 6753683 |
| [long-term follow-up observations on 502 cases of schistosomiasis japonica treated by praziquantel]. | 1982 | 6812909 | |
| adhesion-precipitation technic for schistosome cercariae recovery from natural waters. | 1982 | 6817982 | |
| granuloma formation around exogenous eggs of schistosoma mansoni and schistosoma japonicum in mice. | hepatic granulomata which were qualitatively and quantitatively similar to those seen in infections established with cercariae were induced by surgical injection of exogenous eggs of schistosoma mansoni and schistosoma japonicum via the mesenteric veins of previously unexposed albino mice. thereafter, their comparative histopathologic studies were made. the maximum mean sizes of granulomata were attained on day 32 with viable eggs of these parasite species. although s. mansoni eggs produced sign ... | 1982 | 6301246 |
| [studies on the microsome antigen of schistosoma japonicum. 1. preliminary report on the preparation and antigenic properties of adult worm microsomes]. | 1982 | 6219772 | |
| schistosomiasis: clinical features and relevance to hematology. | 1982 | 7041263 | |
| schistosoma japonicum: immediate hypersensitivity reactions to egg antigen in humans and rodents. | 1982 | 7047199 | |
| adoptive transfer of modulation of granuloma formation and hepatosplenic disease in murine schistosomiasis japonica by serum from chronically infected animals. | the course of disease due to schistosoma japonicum in c57bl/6j mice was examined. animals infected with 25 cercariae of the philippine strain of s. japonicum for 9 wk develop a peak portal hypertension of 13 +/- 0.6 cm h2o and mean hepatic granuloma area of 459 x 10(3) micrometers 2. by 30 wk, disease manifestations were reduced; mean portal pressure was 7 +/- 0.5 cm h2o and mean hepatic granuloma area was 12 x 10(3) micrometers 2. adoptive transfer of serum but not 1 x 10(8) spleen or 4 x 10(7) ... | 1982 | 7057037 |
| correlation between lipid partition coefficients and surface permeation in schistosoma japonicum. | comparison of transintegumental membrane permeability and partition coefficients of selected nonelectrolytes was attempted to correlate the parameters of lipid solubility, hydrophilicity, and membrane permeation in male and female schistosomes (parasites of the portal venous tributaries of man). surface permeation (measured by the triple isotope technique) and octanol/water partition coefficients were determined for 17 compounds (acetamide, aminopyrine, antipyrine, benzyl alcohol, butanol, caffe ... | 1982 | 7057454 |
| hepatic calcification in schistosomiasis japonica. | 1982 | 7069015 | |
| plasma spectrometric analysis for na, k, ca, mg, fe, and cu in schistosoma mansoni and s. japonicum. | the concentration of k, na, ca, mg, fe, and cu in adult schistosoma mansoni and s. japonicum was determined using plasma spectrometric analysis. there was no difference in elemental composition of schistosoma mansoni pairs that were incubated in various media such as rpmi/1640, eagle's medium or hanks' balanced salt solution. these values were also equivalent to those obtained from worms directly extracted with 2% hcl. female worms of both species contained a relatively higher concentration of f ... | 1982 | 7077448 |
| metabolic requirements of schistosomes. | in adult schistosoma mansoni and s. japonicum carbohydrate utilization, formation of lactic acid and atp levels were the same under aerobic and anaerobic conditions. therefore, these parasites exhibited no pasteur effect. when the metabolic requirements of the parasites were raised by 5-hydroxytryptamine-(5-ht)-induced stimulation of the worm's motor activity, aerobic conditions did not reduce the rate of carbohydrate utilization nor the atp levels of the worms. therefore, these parasites do not ... | 1982 | 7077454 |
| schistosoma japonicum in rabbits: differences in the host-parasite relationship over a seven-year period. | rabbits were infected with schistosoma japonicum of japanese origin between 1973 and 1979. the distribution of lesions and eggs in the small intestine and colon changed significantly twice during that period, and the number of eggs per worm pair passed in the feces changed at least once. the shift in egg distribution and that in egg passage occurred at different times and appeared not to be causally related. the number of eggs per worm pair retained in the tissues of chronically infected rabbits ... | 1982 | 7081545 |
| a rapid method for the infection of laboratory mice with schistosoma japonicum. | known numbers of medium-suspended cercariae of schistosoma japonicum were injected either intraperitoneally, subcutaneously, intramuscularly or intravenously into mice and were compared for infectivity with s. japonicum cercariae that had been administered percutaneously. the injected cercariae appeared to be no less infective or fecund even after their maintenance in vitro for up to six hours. the intraperitoneal route of inoculation was preferred as it facilitated the rapid infection of mice a ... | 1982 | 7101404 |
| eradication of schistosomiasis. | 1982 | 7102873 | |
| control of schistosomiasis japonica in the nagatoishi area of kurume, japan. | a pilot experiment using napcp as a molluscicide to control schistosomiasis japonica was initiated in 1950--51 in nagatoishi-cho, kurume, japan, where 1,050 persons lived behind dikes built to prevent flooding from the chikugo river. they farmed 60 ha of rice, and 72.9% of them were infected with schistosomiasis. at the end of 2 years, 99.5% of the snails (oncomelania h. nosophora) were controlled and new cases dropped from 30--35 per year to 5 and 0 at the end of the 1st and 2nd year, respectiv ... | 1982 | 7102909 |
| further studies on the susceptibility of new taiwan foci of oncomelania hupensis to geographic strains of schistosoma japonicum. | two known colonies of o.h chiui in alilao and of o.h. formosana in changhua and four new foci of snails in nantou, chiayi, hualien and taitung on taiwan were exposed each to 5 miracidia of changhua zoophilic strain and chinese, philippine and indonesian anthropopilic or human strains of s. japonicum. the results showed that all four new foci demonstrated various degrees of susceptibility to this parasite. infectivity of chinese strain of s. japonicum in 4 new foci of snails is reported for the f ... | 1982 | 7112218 |
| serologic responses to schistosoma japonicum: evaluation of total and parasite-specific immunoglobulins during the course of murine infection. | mice with a primary infection of schistosoma japonicum develop high levels of both total immunoglobulins and parasitic-specific antibodies, beginning about 1.5 wk after the onset of oviposition in the host. radial immunodiffusion demonstrated an 18-fold, fivefold, and threefold increase in the levels of igg1, igm, and iga, respectively, during the course of infection. schistosoma japonicum-specific antibodies, as measured by an enzyme-linked immunoabsorbent assay, appeared and increased at about ... | 1982 | 7119981 |
| parasitological and pathological findings in capuchin monkeys infected with schistosoma japonicum or schistosoma mansoni. | capuchin monkeys were studied for 7 months after exposure to schistosoma mansoni or to either a japanese or a philippine strain of schistosoma japonicum. the number of eggs present in the tissues and passed in the feces of s. mansoni-infected monkeys correlated well with the number of worm pairs recovered. monkeys infected with the philippine strain of s. japonicum passed large numbers of eggs in the feces and the number of these eggs correlated well with the number of worm pairs present. in mon ... | 1982 | 7125064 |
| [development of schistosoma japonicum in the intermediate host oncomelania hupensis hupensis snail]. | 1982 | 7126136 | |
| comparison of recovery of schistosomula of schistosoma japonicum from lungs of mice and rats. | various strains of mice and rats were exposed to small doses of schistosoma japonicum cercariae. at intervals, they were challenged with 200 to 230 cercariae per mouse and 500 to 520 cercariae per rat. age-matched control animals received only the challenge infection from the same pool of cercariae. recoveries of schistosomula from experimental and control groups were different on day 3 through day 5, with peak recovery on day 3 or 4 in four strains of mice examined (dba/2, c57bl/6, c3h/he, and ... | 1982 | 7131184 |
| isolation of a concanavalin a-binding glycoprotein from adult schistosoma japonicum. | 1982 | 7131202 | |
| population studies on oncomelania quadrasi, the snail intermediate host of schistosoma japonicum, in the philippines. 3. data transformation for significance test of snail density. | for the comparative study of densities of oncomelania quadrasi, the snail intermediate host of schistosoma japonicum in the philippines, the survey data should be transformed to stabilize the variance in determining the significant difference of densities among populations and to evaluate control measures by the difference, since the snail is distributed unevenly in the field. comparison was made for the efficiency of stabilizing variance among 7 transformation formulas so far reported, and 2 ne ... | 1982 | 7131853 |
| resistance of mice to secondary infection with schistosoma japonicum, with special reference to neutrophil enriched response to schistosomula in the skin of immune mice. | the lung recovery assay for schistosomula has been used as a rapid method for measuring acquired resistance to schistosoma mansoni infection in challenged animals. this assay method was successfully utilized in the present study with s. japonicum in mice. assay of resistance to reinfection with the lung recovery technique and with the conventional perfusion method demonstrated that a considerable level of resistance developed in mice which had received the primary infection of 30 s. japonicum ce ... | 1982 | 7131856 |
| morphological alterations of schistosoma japonicum associated with the administration of amoscanate. | morphological alterations of schistosoma japonicum induced by the administration of a curative dose (20 mg/kg) of the schistosomicide, amoscanate (4-isothiocyanate-4'-nitrodiphenylamine, cgp4540), were studied. worms from amoscanate-treated ddy mice exhibited remarkable changes on the surface of male and female worms, as well as in the vitelline cells of females. various types of lesions, such as swelling and ballooning of the tegument, constriction of folds and channels, disruption of sensory r ... | 1982 | 7131858 |
| enzyme-linked immunosorbent assay with egg antigens of schistosoma japonicum. | a micromethod of the enzyme-linked immunosorbent assay (elisa) was applied to infections with schistosoma japonicum in humans and mice with egg antigens. in mouse infections, antibody responses were detected between 6 and 8 weeks after the cercarial challenge. in human infections, a circum oval precipitin positive group showed the highest reaction values in elisa. elisa with egg antigens did not show any cross reaction with sera of humans infected with intestinal parasites (ascaris, trichuris an ... | 1982 | 7136190 |
| isolation of schistosoma japonicum egg glycoprotein antigens which sensitize mice to lung granuloma formation and elicit an immediate hypersensitivity response. | crude schistosoma japonicum soluble egg antigen (sea) could be resolved into at least 25-30 coomassie blue-reactive polypeptides when subjected to polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. two of these polypeptides also gave a strong reaction for carbohydrate with the periodic acid-schiff (pas) reagent. although only four antigens could be demonstrated by double immunodiffusion in agar against the sera of mice with a 9-week s. japonicum infection, double antib ... | 1982 | 7149104 |
| [study on fragility of mast cells in skin tissue in mice infected with schistosoma japonicum]. | 1982 | 7150000 | |
| lung granulomatous hypersensitivity to eggs of schistosoma japonicum in mice analysed by a radioisotopic assay and effects of hybridoma (idiotype) sensitization. | the radioisotopic assay for acute granulomatous hypersensitivity (agh) to eggs of schistosoma japonicum in mice sensitized with eggs in adjuvant has been examined in the high responder strain. c57bl/6. responsiveness is expressed as the lung-kidney ratio of radioactivity in mice challenged intravenously with eggs and injected with 125i-iododeoxyuridine. eggs vary in their agh sensitizing and eliciting potency; eggs proven to be superior in the circumoval precipitation (cop) test for detection of ... | 1982 | 7150121 |
| [phenithionate(phenyl-4-nitrodiphenylamine-4'-thionocarbamate) in the treatment of schistosomiasis japonicum--a preliminary report on 463 cases]. | 1982 | 7151549 | |
| [the in vitro effect of agrimophol on schistosoma japonicum]. | 1982 | 7158350 | |
| [sythesis and antischistosomal action of phenithionate and related derivatives of thiocarbamic acid]. | 1982 | 7158351 | |
| an epidemiological study on schistosoma japonicum in domestic animals in leyte, philippines. | an epidemiological study of schistosoma japonicum in domestic animals in two municipalities of the eastern coastal plain of leyte, philippines, showed that pigs and dogs have the highest rates of prevalence. dogs had the highest mean 24-hour egg output, and pigs the proportion of hatchable eggs. however, dogs serve an important role in maintaining the transmission of the parasite as indicated by a high transmission potential and the close habitual contact of the animals to human. although necrop ... | 1982 | 7170639 |
| studies on the susceptibility of new taiwan foci of oncomelania hupensis to ilan and japanese strains of schistosoma japonicum. | sixty snails from four new foci of o. hupensis in taitung, chiayi, hualien and nantou counties, and 4 known colonies of o. h. chiui in alilao and pali in taipei as well as of o. h. formosana in changhua and ilan on taiwan were exposed each to 5 miracidia of ilan zoophilic strain and japanese anthropophilic or human strain of s. japonicum. this is the first report to note that all four new foci of o. hupensis snails were highly susceptible to ilan strain of s. japonicum (17-20%). susceptibility t ... | 1982 | 7170640 |
| malignant schwannoma occurring with schistosoma japonicum: a case report. | an 18-year-old filipina presented with a 28 cm retroperitoneal malignant schwannoma arising from the sigmoid colon. histopathologic examination revealed the presence of numerous schistosome ova immediately adjacent to the tumor and throughout the submucosa. due to the rarity of malignant schwannomas, their infrequent occurrence in young persons in the absence of von recklinghausen's neurofibromatosis, and the presence of schistosomal ovideposition, the possible role of schistosomal infection in ... | 1982 | 7170642 |
| protein, glycogen, and water content in schistosomes. | the volume of distribution (= vd) of water was measured in schistosoma mansoni, s. haematobium, s. japonicum, and hymenolepis diminuta. in the rat tapeworm, h. diminuta, the volume of distribution of 3h-water was positively correlated with wet weight (r = 0.87, p less than 0.001) and this same phenomenon also was demonstrated in s. mansoni (r = 0.90, p less than 0.001). the 5-sec vdwater was constant over a range of glucose (0.01-50 mm) and phenylalanine (0.01-20 mm) concentrations in both male ... | 1982 | 7175609 |
| population studies on oncomelania quadrasi, the snail intermediate host of schistosoma japonicum, in the philippines. 4. evaluation of drainage for snail control. | 1982 | 7176144 | |
| schistosoma japonicum: migration of adult worm pairs within the mesenteric veins of mice. | mice infected with a single worm pair of a japanese, a philippine and a formosan strain of schistosoma japonicum were examined to determine the frequency of movement of worms within the mesenteric veins eight to 76 weeks after infection. by the 18th week after infection, one or more gross focal lesions developed in the gut, and 47 to 89% of eggs in the gut were concentrated in these lesions. in spite of this predominantly focal oviposition, oograms revealed first-stage eggs scattered throughout ... | 1982 | 7179417 |
| [scanning electron microscope observations on tegumental surface alterations of schistosoma japonicum induced by pyquiton]. | 1982 | 7180480 | |
| [comparison of the cercarial chaetotaxy of 10 species of schistosomes]. | the cercarial chaetotaxy permits the differenciation of four groups of schistosomatinae. --schistosomatium douthitti, parasite of stagnicola and lymnaea (lymnaeidae); --schistosoma japonicum, parasite of oncomelania (melaniidae); --schistosoma mansoni and s. rodhaini, parasites of biomphalaria (planorbiinae, bulinidae); --schistosoma haematobium, s. bovis, s. margrebowiei, s. mattheei, s. leiperi and s. intercalatum, parasites of isidora, physopsis and bulinus (bulininae, bulinidae). for the thi ... | 1982 | 7181377 |
| [observation of various immunological indices in 207 patients with schistosomiasis]. | 1982 | 7182137 | |
| a study of ultrastructure of egg shell of schistosoma japonicum. i. transmission electron microscopic observation of s. japonicum egg. | ultrathin sections of egg shell of s. japonicum were observed. the micropores and network of microcanals were first reported in egg shell of s. japonicum. both the micropores and microcanals are lined by a membrane being continous with the inner layer of egg shell and filled with materials coming from inside of the egg. as in the egg of s. mansoni, the possibility of micropores and microcanals that may play an important role as natural channels in secreting materials such as soluble antigens and ... | 1982 | 7187198 |
| [superficial argyrophilic structures of the infective larval forms of schistosoma japonicum]. | integumentary argentophilic structures in miracidium and cercaria of schistosoma japonicum, chinese strain, are described in detail. - miracidium. the pattern of organites between the first and second tier and between the second and third tier in miracidia of s. japonicum is identical to that in miracidia of s. incognitum, but differs from that seen in miradicia of other species of schistosoma. - cercaria. chaetotaxy differs from that reported in a previous study but, in our opinion, these diffe ... | 1982 | 7187199 |
| "control of schistosomiasis": morbidity-reduction and chemotherapy. | 1982 | 7188153 | |
| epidemiology of schistosomiasis. | 1982 | 7188157 | |
| circulating antigens in schistosoma-infections. | 1982 | 7188159 | |
| collaborative study on antigens for immunodiagnosis of schistosomiasis. | eight research laboratories in europe and the united states of america were selected on the basis of having published data on schistosoma mansoni and s. japonicum antigens to participate in a study of various antigen/test combinations for immunodiagnosis of schistosomiasis. the serum bank consisted of 395 well documented sera from four endemic areas in brazil (2 areas), kenya, and the philippines. altogether, 21 s. mansoni and four s. japonicum antigen and immunoassay combinations were evaluated ... | 1982 | 6983926 |
| studies on the host-parasite relationship of schistosoma japonicum in normal and immunosuppressed mice. | infections of schistosoma japonicum were studied in mice which were immunosuppressed either by thymectomy and administration of antithymocyte serum or by treatment with hydrocortisone acetate. the relation of s. japonicum with the immunosuppressed host differed with that reported for schistosoma mansoni. the pathogenesis of the s. japonicum infection in the immunosuppressed host was less severe than that caused by s. mansoni, with respect to survival of, and hepatocellular damage to, the host. i ... | 1982 | 6984166 |
| [studies on chemotherapy of parasitic helminths (iv). effects of alkaloids from sophora flavescens on the motility of parasitic helminths and isolated host tissues (author's transl)]. | effects of n-methylcytisine (n-mc) and matrine (mat), alkaloids from sophora flavescens on the motility of parasitic helminths and isolated frog rectus and mouse ileum were studied. 1) the motility of angiostrongylus cantonensis was affected spastically by n-mc (1.2 x 10(-6) approximately 1.2 x 10(-4) m), but paralytically by mat (10(-5) approximately 10(-4) m). 2) the motility of dipylidium caninum and fasciola hepatica was affected paralytically by n-mc (1.2 x 10(-4) approximately 1.2 x 10(-3) ... | 1982 | 7200047 |
| [studies on chemotherapy of parasitic helminths (iii). effects of tuberostemonine from stemona japonica on the motility of parasitic helminths and isolated host tissues (author's transl)]. | effects of tuberostemonine (ts), an alkaloid from stemona japonica, on the motility of parasitic helminths and isolated frog rectus and mouse ileum were studied. 1) ts (6.7 x 10(-6) approximately 2 x 10(-5) m) paralyzed the motility of angiostrongylus cantonensis. 2) ts (6.7 x 10(-5) m) showed contractive effects on the motility of dipylidium caninum and fasciola hepatica. 3) treatment with ts (6.7 x 10(-5) approximately 4.8 x 10(-4) m) had little effect on the motility of schistosoma japonicum. ... | 1982 | 7200048 |
| a comparative study of the vitelline cell in schistosoma mansoni, s. haematobium, s. japonicum and s. mattheei. | a comparison is given of the ultrastructure of the vitelline cell in schistosoma mansoni, s. haematobium, s. japonicum and s. mattheei. four stages in development of the vitelline cell have been categorized as follows: stage 1, the undifferentiated cell; stage 2, the developing cell showing the beginning of synthetic activity; stage 3, the developing cell showing active protein synthesis; stage 4, the fully mature vitelline cell. these stages in development have been defined morphologically and ... | 1982 | 7200223 |
| purification and characterization of a high molecular weight eosinophil chemotactic factor from schistosoma japonicum eggs. | a high m.w. eosinophil chemotactic factor (ecf-sje) was isolated and purified from a soluble egg antigen preparation (sea) of schistosoma japonicum by gel filtration on sephacryl s-200, anion-exchange chromatography on de52, and isoelectric focusing. ecf-sje had a m.w. of more than 900,000 and an isoelectric point of 4.1. it contained 40% (w/w) sugar residues and bound to concanavalin a (con a). the chemotactic activity of ecf-sje was heat stable (100 degrees c, 60 min) and resistant to pronase ... | 1982 | 6889620 |
| new methods of purifying and identifying parasitic diagnostic antigens: a review of the systematic and quantitative approach with the schistosoma model. | several antigen preparations intended for use in the serodiagnosis of schistosomiasis were reviewed. the efficacies of these antigens in terms of specific activities and cross-reactivities were compared. the idea of quantitation of the actual usable amount of antigens in various preparations was introduced. a systematic approach to the purification and identification of relevant antigens in the schistosoma system was discussed. use of the quantitative single-tube kinetic-dependent enzyme-linked ... | 1982 | 6890267 |
| isozyme patterns of schistosoma japonicum and s. mansoni. | isozyme patterns of six enzymes, glucose-6-phosphate dehydrogenase, glucosephosphate isomerase, hexokinase, malate dehydrogenase, 6-phosphate dehydrogenase and phosphoglucomutase were examined in electrophoresed homogenates of adult male worms of schistosoma japonicum and s. mansoni. in general, enzyme patterns obtained from the parasite homogenates differed from that of host (mouse) blood and muscle, indicating that electrophoretic patterns from parasite extracts are most probably of parasite o ... | 1983 | 6221047 |
| [effect in vitro of metabolites of praziquantel on schistosoma japonicum]. | 1983 | 6223498 | |
| nutritional requirements of schistosoma japonicum eggs. | newly laid eggs of schistosoma japonicum were cultured in a serum-free, chemically defined medium, rpmi 1640, which contained 20 amino acids, glutathione, 11 vitamins, and glucose in a balanced salt solution. the requirements for these components in the nutrition of the eggs was investigated by the deletion of single component from the medium. the following 14 amino acids were shown to be essential for the full development of the egg in the medium: l-arginine, l-cystine, glycine, l-histidine, l- ... | 1983 | 6231359 |
| recurrent lumbosacral and brachial plexopathy associated with schistosomiasis. | 1983 | 6311145 | |
| schistosoma and related genera: acquired resistance in mice. | 1983 | 6337057 | |
| hybridoma antibody-based competitive elisa in schistosoma japonicum infection. | a competitive enzyme-linked immunosorbent assay (elisa) has been developed and compared with the circumoval precipitin test (copt) for diagnosis of schistosomiasis japonica using philippine sera. the assay is based on the inhibition, by sera, of the binding of a penicillinase-conjugated hybridoma-derived antibody, i. 134, to a crude schistosoma japonicum adult worm extract. a change in ph subsequent to addition of the substrate is used as the indicator system. development of the color change in ... | 1983 | 6337516 |
| fluorescent histochemistry of acid proteases in adult schistosoma mansoni and schistosoma japonicum. | the acid proteases, cathepsin b, dipeptidyl aminopeptidase i and ii were demonstrated by fluorescent histochemistry in adult schistosoma mansoni and schistosoma japonicum. alanyl- and leucine-aminopeptidase activities were not observed. the substrates consisted of 4-methoxy-beta-naphthylamide derivatives coupled to the fluorescent molecule, 5-nitrosalicylaldehyde. reaction product was observed as discrete granules in the gastrodermis; activity was also observed in the testes and vitelline cells ... | 1983 | 6338188 |
| ultrastructural investigations on the effects of praziquantel on human trematodes from asia: clonorchis sinensis, metagonimus yokogawai, opisthorchis viverrini, paragonimus westermani and schistosoma japonicum. | the effect of praziquantel (biltricide) on the ultrastructure of trematodes pathogenic to man in asia was investigated in: clonorchis sinensis, opisthorchis viverrini, schistosoma japonicum, metagonimus yokogawai, and paragonimus westermani. the different parasites were isolated from their respective experimental hosts and uniformly incubated for 5, 15, 30 or 60 min at 37 degrees c in medium tc 199 containing 0, 1, 10 or 100 micrograms praziquantel/ml. all parasites exposed to praziquantel were ... | 1983 | 6338885 |
| localization of antigen within eggs of schistosoma japonicum that participate in circumoval precipitin (cop) reaction. | 1983 | 6343579 | |
| seroepidemiology of schistosomiasis japonica by elisa in the philippines. i. underestimation by stool examination of the prevalence of infection in school children. | in a longitudinal seroepidemiological study in the schistosoma japonicum endemic area of leyte, the elisa technique to determine prevalence and incidence rates in elementary school children was compared with similar determinations made by a modified quantitative stool examination (mifc). in the area of this study, barrio salvador, tanauan, leyte, the ongoing schistosomiasis japonica control program in the philippines is dependent on stool examination by mifc and/or the quantitative thick smear ( ... | 1983 | 6359910 |
| evaluation of micro-elisa for schistosomiasis japonica using crude egg antigen. | procedures of micro-elisa for detecting antibody of schistosoma japonicum infection were improved by using crude egg antigen, peroxidase-labeled antibody and o-phenylenediamine on a micro-elisa plate (m129a, dynatech). reactions were performed with 0.1 ml of reagents in 0.3 ml wells at each step and 0.3 ml of substrate was placed at the final procedure. the endpoint of reaction was defined as the upper limit of 99% critical range of absorbance in negative sera at 1:40 dilution which was approxim ... | 1983 | 6363767 |
| lung-stage expression of a major schistosome surface antigen. | the topographical expression of a glycoprotein of 180,000 molecular weight on the surface of lung-stage schistosoma mansoni schistosomula was determined by immunofluorescence microscopy using a monoclonal antibody. postfixation treatment with graded ethanols enhanced specific immunofluorescent staining of adult worms, and was required for detection of the antigen on the surfaces of lung-stage schistosomula. the epitope recognized by the monoclonal antibody was also present on the surfaces of adu ... | 1983 | 6371211 |
| [studies on the antigens common to adult worm and cercaria of schistosoma japonicum]. | 1983 | 6380794 | |
| [urease-antibody conjugate elisa and its application in the diagnosis of schistosomiasis japonica--a preliminary report]. | 1983 | 6380804 | |
| liver collagen synthesis and degradation in schistosomiasis. | 1983 | 6825441 | |
| vaccination against bovine schistosomiasis japonica with highly x-irradiated schistosomula. | cercariae of the chinese mainland strain of schistosoma japonicum were used. eighteen cattle, divided into six groups of three each, were immunized with schistosomula transformed from cercariae exposed to three different doses of x-irradiation (24, 36, and 48 kr). the immunization was given either once, twice, or thrice, and the number of immunizing schistosomula was 10,000 or more in each immunization. the immunized cattle were challenged with 500 normal cercariae. five native cattle were simil ... | 1983 | 6837845 |
| schistosoma japonicum: immunological response to circulating polysaccharide antigens in rabbits with a light infection. | to study the detectability of circulating polysaccharide antigens and the immunological response to such antigens in rabbits with a light schistosoma japonicum infection, sera of five rabbits infected with 50 cercariae were studied up to 29 weeks post infection (p.i.). while one rabbit developed no worm burden, the other rabbits developed low worm burdens (4 to 16 worms). in the sera of these rabbits, the only polysaccharide antigen demonstrable with immunoelectrophoresis (ief), was the circulat ... | 1983 | 6852173 |
| [histological and histochemical changes of schistosoma japonicum and host liver caused by artemether]. | 1983 | 6858697 | |
| [electron microscopic studies on the effect of nithiocyamine on schistosoma japonica]. | 1983 | 6880755 | |
| immunoglobulin m-immunoglobulin g mixed cryoglobulinemia in schistosoma japonicum-infected rabbits. | cryoprecipitation was observed in defibrinated serum from schistosoma japonicum-infected rabbits. ouchterlony immunodiffusion, sodium dodecyl sulfate-polyacrylamide gels, and anti-cryoprecipitate antiserum demonstrated the presence of immunoglobulin g (igg), igm, c3, fibrinogen, and an alpha-macroglobulin. parasite antigen was not detected. igg and igm from pooled cryoprecipitates failed to react with each other in ouchterlony immunodiffusion gels after separation by column chromatography. the d ... | 1983 | 6404826 |
| [ultrastructure of ovum shell and circumoval precipitates of schistosoma japonicum]. | 1983 | 6413032 | |
| phenithionate in schistosomiasis japonica. preliminary report of 463 cases. | 1983 | 6413140 | |
| abo blood group and late schistosomiasis japonica. | 1983 | 6413161 | |
| malate dehydrogenase isozymes in schistosoma japonicum (chinese mainland strain) by electrophoresis. | 1983 | 6418450 | |
| immunologic function in schistosomiasis japonica patients before and after treatment. | 1983 | 6426886 | |
| resistance to reinfection with schistosoma japonicum in the mouse. | balb/c and outbred mice infected with a philippine isolate of schistosoma japonicum for 50 to 60 days expressed strong resistance to reinfection. the extent of this reinfection resistance ranged from 72 to 93% in 5 experiments (mean = 80% resistance) as determined by numbers of immature worms recovered from already infected and age- and sex-matched challenge control mice exposed 20 days previously to cercariae. determination of numbers of recoverable worms from (the initial) infection suggest th ... | 1983 | 6612418 |
| preliminary research on relationship between late stage schistosomiasis japonica and liver autoimmunity: measuring anti-lsp level by radioimmunoelectrophoresis. | 1983 | 6621976 | |
| [observation on tegument damage of schistosoma japonicum and penetration of host leukocytes into the worm body caused by pyquiton]. | 1983 | 6624466 | |
| [effect of pyquiton derivatives in experimental schistosomiasis japonica]. | 1983 | 6624468 | |
| efficacy of amoscanate against experimental schistosomal infections in monkeys. | the antischistosomal activity of oral doses of amoscanate (4-isothiocyanato-4'-nitrodiphenylamine) was determined in infected cebus apella (capuchin monkeys) and macaca mulatta (rhesus monkeys). in c. apella infected with schistosoma japonicum or s. mansoni an initial dose of 10 mg/kg body weight did not alter fecal egg counts, but a subsequent dose of 25 mg/kg markedly reduced both egg counts and worm burdens; in animals infected with s. haematobium, a single dose of 25 mg/kg of amoscanate was ... | 1983 | 6625061 |
| [one-dose regimen of praziquantel in the treatment of chronic schistosomiasis japonica]. | 1983 | 6628093 | |
| innate resistance to schistosoma japonicum in a proportion of 129/j mice. | 1983 | 6631630 | |
| [7 types of cerebral complications of schistosomiasis japonica]. | 1983 | 6639799 | |
| schistosoma mansoni, s. japonicum, s. haematobium: glycogen content and glucose uptake in parasites from fasted and control hosts. | the glycogen content of male and female schistosoma mansoni has been measured in flukes from normally fed hosts and those from fasted hosts. in infections from both the mouse and the hamster, a significant reduction in schistosomal glycogen of males is seen hours after food is withdrawn from the host. reductions in protein content of the schistosomes were only observed in hamster infections fasted at least 72 hr. the livers of infected mice not only decrease in size during fasting, but there is ... | 1983 | 6641897 |
| [bacterio-parasitic interactions. enterobacteria and schistosomes (salmonella - schistosome association)]. | the description of a case imported from chad of an association of salmonella typhi - schistosoma haematobium and, in this connection, a new revised general account. the association salmonella-schistomas is wide-spread. it corresponds to a salmonello - schistosomo - micro - association by the fixation of precise bacteria in the case of a bacteriemia on the cutaneous surface of male schistosomes in clearly defined places. these salmonella constitute a permanent antigenic solicitation and they are ... | 1983 | 6645880 |
| the host-parasite relationship of schistosoma japonicum in cba mice. | the host-parasite relationship of the chinese mainland strain of schistosoma japonicum in cba mice is described and compared to previous reports on this parasite in mice. s. japonicum took under 2 weeks to complete its migration to the portal system of mice, and peak passage of schistosomula through the lungs occurred 5-6 days after infection. the mean percentage establishment of worms, which was independent of the infecting inoculum, was 46%. the adult worm burdens remained constant over a 28-w ... | 1983 | 6646812 |
| immunodiagnosis of schistosomiasis haematobium and schistosomiasis mansoni in man. application of crude extracts from adult worms and cercariae in the iha and the elisa. | the antibody responses of patients infected with s. haematobium or s. mansoni were investigated in an indirect hemagglutination test (iha) and an enzyme linked immunosorbent assay (elisa) using crude extracts of cercariae and adult worms of s. haematobium and s. mansoni, and of adult worms of s. japonicum. patients were africans from endemic areas, as well as europeans who had acquired their infection relatively recently. although the iha showed a similar pattern of antibody responses as the eli ... | 1983 | 6649986 |
| relationship of prevalence and intensity of infection to morbidity in schistosomiasis japonica: a study of three communities in leyte, philippines. | to determine whether prevalence and intensity of infection are factors in morbidity in schistosomiasis japonica, a cross-sectional study was undertaken in three villages in leyte, philippines, namely, santol (a), santa rosa (b), and macanip (c). kato thick-smear fecal examination and egg counts were made on 289 of 341 residents in village a (85%), 824 of 1,008 in village b (82%), and 1,113 of 1,241 in village c (90%). prevalences of 26%, 39%, and 44%, respectively, were found in the three villag ... | 1983 | 6650734 |
| attempts to modify lung granulomatous responses to schistosoma japonicum eggs in low and high responder mouse strains. | a radioisotopic assay for acute granulomatous hypersensitivity (agh) to lyophilized eggs of schistosoma japonicum has been used to further examine responses to egg antigens in various inbred strains of mice. the ranking of responsiveness in mice from high (c57bl/6), intermediate (balb/c) to low (cba/h) was not influenced by high or low egg-sensitization regimens. however, the low responsiveness of responder mice sensitized with eggs by the intraperitoneal compared with the subcutaneous route of ... | 1983 | 6651645 |
| schistosoma japonicum: a comparison of the development of the parasite and associated pathological changes in mice and jirds (meriones unguiculatus). | 1983 | 6654579 | |
| morbidity in schistosomiasis japonica in relation to intensity of infection. a study of two rural brigades in anhui province, china. | schistosomiasis japonica remains endemic in several provinces south of the yangtze river in china because of relatively sparse populations of human beings and dense populations of snails. we studied two brigades in a rural commune in gui-chi county, anhui province, to determine the prevalence, intensity, and morbidity associated with this infection before concerted control efforts were instituted. quantitative fecal examinations, histories, and physical examinations relevant to schistosomiasis j ... | 1983 | 6656848 |
| longitudinal study on schistosoma japonicum infections in the philippines. 3. incidence and environmental modification at dagami, leyte. | the yearly change of incidence of schistosomiasis japonica was observed among 1800 children enrolled in 9 schools situated within a 5 km radius around dagami poblacion, leyte, philippines from school year (sy) 1974/75 to 1979/80. the purpose of this observation was to know the effect of environmental modification undertaken in about 50 ha of snail-infested and abandoned rice field which is the most depressed and central portion of this project area. children were examined by egg detection from s ... | 1983 | 6663805 |
| transfer of delayed hypersensitivity induced by schistosoma japonicum adult worm antigen in guinea pigs. | 1983 | 6663808 | |
| lack of resistance to schistosoma japonicum in mice immunized with irradiated s. mansoni cercariae. | mice immunized with irradiated schistosoma mansoni cercariae were resistant to challenge with s. mansoni cercariae (mean resistance 53%) but not to challenge with s. japonicum cercariae (mean resistance -5%). furthermore, the antibodies induced by vaccination with irradiated s. mansoni cercariae were more reactive with s. mansoni than with s. japonicum schistosomula. these results support the concept that the resistance induced by vaccination with irradiated cercariae is immunologically specific ... | 1983 | 6665834 |
| microtopography of the surface of adult schistosoma japonicum-like (malaysian) as observed by scanning electron microscopy. | the surface of adult schistosoma japonicum-like (malaysian) was studied by scanning electron microscopy. the basic pattern of surface microtopography is similar to other strains of s. japonicum as previously reported. however, among male member there are some unique differences in the types, number and distribution of surface papillae and morphology of ridges. three kinds of papillae were observed: (1) the large fungiform papillae (3.5-4 micron in diameter, most without cilia) are more numerous ... | 1983 | 6673118 |
| circumoval precipitin (cop) test using air-dried eggs of schistosoma japonicum and s. mansoni. | in an attempt to establish a simplified circumoval precipitin (cop) test for the diagnostic purpose of schistosomiasis, air-dried eggs of both schistosoma japonicum and s. mansoni were tested as antigens for this assay. twenty-six sera from mice infected with s. japonicum showed positive cop reactions as assessed by air-dried eggs. among 36 serum samples from patients with schistosomiasis japonica, five exhibited false negative reaction when assessed with air-dried eggs and showed a minimum leve ... | 1983 | 6673119 |
| hbv exposure and hbsag positivity rates in schistosomiasis japonica: study in a philippine community endemic for both infections. | hbv exposure and hbsag positivity rate were examined in 561 residents of an area endemic for s. japonicum and 22 additional cases with severe hss japonica were also included. the differences in hbv exposure and hbsag positivity rates among the groups without the parasitism, with schistosomiasis japonica and with hss (53 cases) were not statistically significant. comparison of the same parameters between those with and without s. japonicum infection according to sex and age groupings did not also ... | 1983 | 6673120 |