Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| frequency and diversity of class a extended-spectrum beta-lactamases in hospitals of the auvergne, france: a 2 year prospective study. | to evaluate the frequency and diversity of extended-spectrum beta-lactamases (esbls) produced by enterobacteriaceae and pseudomonas aeruginosa in one french region. | 2004 | 15282240 |
| use of tuf sequences for genus-specific pcr detection and phylogenetic analysis of 28 streptococcal species. | a 761-bp portion of the tuf gene (encoding the elongation factor tu) from 28 clinically relevant streptococcal species was obtained by sequencing amplicons generated using broad-range pcr primers. these tuf sequences were used to select streptococcus-specific pcr primers and to perform phylogenetic analysis. the specificity of the pcr assay was verified using 102 different bacterial species, including the 28 streptococcal species. genomic dna purified from all streptococcal species was efficient ... | 2004 | 15297518 |
| molecular epidemiology of enterobacteriaceae isolates producing extended-spectrum beta-lactamases in a french hospital. | in 2002, 80 isolates of enterobacteriaceae producing extended-spectrum beta-lactamases (esbls) were collected from infected patients in our hospital. enterobacter aerogenes was the most common bacterium isolated from all specimens (36.5%). the esbls were predominantly (90%) tem derivatives (tem-24, tem-3). pulsed-field gel electrophoresis highlighted that e. aerogenes, klebsiella pneumoniae, and citrobacter koseri had a clonal propagation. | 2004 | 15297534 |
| [incidence of extended spectrum beta-lactamase (esbl)-producing enterobacteria in the area of caltagirone (sicily)]. | the authors report the incidence of extended spectrum b-lactamases (esbl)- producing strains in 1,602 enterobacteria consecutively isolated, from april 2002 to december 2003, in caltagirone (ct) hospital, and their in vitro susceptibility to several antimicrobial agents. the incidence of esbl-producing enterobacteria was equal to 1.5%, mainly among escherichia coli, klebsiella spp and citrobacter koseri, isolated by emergency and medicine wards. in vitro, the enterobacteria were fully susceptibl ... | 2004 | 15316296 |
| a selective differential medium for enterobacter sakazakii, a preliminary study. | enterobacter sakazakii can cause fatal invasive infection of neonates associated with the presence of this organism in powdered infant milk formula. a new chromogenic medium (druggan-forsythe-iversen agar, dfi) is described for the selective detection of this emergent pathogen. the medium is based on the alpha-glucosidase reaction which is detected using 5-bromo-4-chloro-3-indolyl-alpha,d-glucopyranoside (xalphaglc). ent. sakazakii hydrolyses this substrate to an indigo pigment, producing blue-g ... | 2004 | 15364468 |
| citrobacter koseri infection and abscess associated with harrington rods. | 2004 | 15454901 | |
| phylogeny, clinical associations, and diagnostic utility of the pilin subunit gene (sfpa) of sorbitol-fermenting, enterohemorrhagic escherichia coli o157:h-. | the plasmid-borne sfpa gene encodes the pilin subunit in sorbitol-fermenting (sf) enterohemorrhagic escherichia coli (ehec) o157:h-. we investigated the distribution of sfpa among 600 e. coli isolates comprising the complete e. coli standard reference (ecor) and diarrheagenic e. coli (dec) strain collections and clinical isolates associated with enteric disease. sfpa was detected in dec3f sf ehec o157:h- strain 493/89, each of 107 sf ehec o157:h- clinical isolates, and 14 shiga toxin-negative sf ... | 2004 | 15472329 |
| two novel real-time reverse transcriptase pcr assays for rapid detection of bacterial contamination in platelet concentrates. | the incidence of platelet bacterial contamination is approximately 1 per 2,000 units and has been acknowledged as the most frequent infectious risk from transfusion. in preliminary studies, the sterility of platelet concentrates (pcs) was tested with an automated bacterial blood culturing system and molecular genetic assays. two real-time reverse transcriptase pcr (rt-pcr) assays performed in a lightcycler instrument were developed and compared regarding specificity and sensitivity by the use of ... | 2004 | 15472337 |
| identification and phylogeny of enterobacter sakazakii relative to enterobacter and citrobacter species. | the phylogenetic relationships of enterobacter sakazakii strains were investigated using 16s ribosomal dna (rdna) and hsp60 sequencing. each analysis distributed e. sakazakii strains among four clusters, indicating substantial taxonomic heterogeneity. the e. sakazakii type strain 16s rdna sequence was 97.8% similar to that of citrobacter koseri but 97.0% similar to that of enterobacter cloacae. | 2004 | 15528745 |
| histidine decarboxylase in enterobacteriaceae revisited. | with a modification of taylor's decarboxylation broth, histidine decarboxylase was detected in enterobacter aerogenes, morganella morganii, raoultella ornithinolytica, and some strains of citrobacter youngae and raoultella planticola. this method provides a useful confirmatory test for identification of e. aerogenes strains. | 2004 | 15583342 |
| clinical microbiology of bacterial and fungal sepsis in very-low-birth-weight infants. | twenty percent of very-low-birth-weight (<1500 g) preterm infants experience a serious systemic infection, and despite advances in neonatal intensive care and antimicrobials, mortality is as much as threefold higher for these infants who develop sepsis than their counterparts without sepsis during their hospitalization. outcomes may be improved by preventative strategies, earlier and accurate diagnosis, and adjunct therapies to combat infection and protect the vulnerable preterm infant during an ... | 2004 | 15258097 |
| evaluation of the new vitek 2 card for identification of clinically relevant gram-negative rods. | the vitek 2 card for gram-negative bacteria (biomérieux,marcy-l'etoile, france) has been redesigned to improve the identification of fermenting and nonfermenting bacilli. forty-seven biochemical tests, including 19 enzymatic tests, are present in the new card and interpreted in a kinetic mode. final identification results are available within 10 h. the database allows the identification of 159 different taxa. six hundred fifty-five gram-negative rods (gnr; 511 fermenters and 144 nonfermenters), ... | 2004 | 15364991 |
| computer-assisted surveillance for detecting clonal outbreaks of nosocomial infection. | whole-house surveillance for healthcare-associated infection is no longer the recommended practice because of the large personnel time investment required. we developed a computer-based tracking system using microbiologic data as an aid in detecting potential outbreaks of healthcare-associated infections on a hospital-wide basis. monthly total isolates of 25 clinically significant hospital pathogens were tallied from 1991 to 1998 to form a database for future comparison. two different algorithm ... | 2004 | 15004070 |
| microarray-based identification of bacteria in clinical samples by solid-phase pcr amplification of 23s ribosomal dna sequences. | the rapid identification of the bacteria in clinical samples is important for patient management and antimicrobial therapy. we describe a dna microarray-based pcr approach for the quick detection and identification of bacteria from cervical swab specimens from mares. this on-chip pcr method combines the amplification of a variable region of bacterial 23s ribosomal dna and the simultaneous sequence-specific detection on a solid phase. the solid phase contains bacterial species-specific primers co ... | 2004 | 15004052 |
| growing group of extended-spectrum beta-lactamases: the ctx-m enzymes. | 2004 | 14693512 | |
| single daily amikacin versus cefotaxime in the short-course treatment of spontaneous bacterial peritonitis in cirrhotics. | to compare the efficacy and safety of single daily amikacin vs. cefotaxime in the 5-d treatment of spontaneous bacterial peritonitis (sbp). | 2005 | 16425390 |
| increased concentration of the complement split product c5a in acute pyelonephritis during pregnancy. | pregnant women with acute pyelonephritis develop acute respiratory distress syndrome (ards) more frequently than non-pregnant women. the reasons for this remain unknown. the complement system is a complex set of self-assembling proteins that have been implicated in the pathophysiology of ards and sepsis. the purpose of this study was to determine if activation of the complement system occurs in pregnant women with acute pyelonephritis. | 2005 | 16147833 |
| performances of vitek 2 colorimetric cards for identification of gram-positive and gram-negative bacteria. | the purpose of this study was to evaluate the new vitek 2 identification cards that use colorimetric reading to identify gram-positive and gram-negative bacteria (gp and gn cards, respectively) in comparison to fluorimetric cards (id-gpc and id-gnb, respectively). a total of 580 clinical isolates and stock collection strains belonging to 116 taxa were included in the study. of the 249 gram-positive strains tested with both the id-gpc and gp cards, 218 (87.5%) and 235 (94.4%) strains were correct ... | 2005 | 16145083 |
| effect of medium age and supplementation with the biocatalytic oxygen-reducing reagent oxyrase on in vitro activities of tigecycline against recent clinical isolates. | in determining the quality control limits for the clinical laboratory standards institute-recommended quality control organisms with tigecycline, a number of inconsistencies in the results were encountered that appeared to be related to the age of the mueller-hinton broth ii. this study was performed to examine the effect of medium age and supplementation with oxyrase on the activity of tigecycline using a large number of clinical isolates. | 2005 | 16127070 |
| controlled clinical comparison of plastic versus glass bottles of bact/alert pf medium for culturing blood from children. | the plastic pediatric bact/alert (biomérieux, durham, n.c.) pf (ppf) is a new nonvented aerobic culture medium in a clear plastic bottle designed to prevent breakage. we compared the performance of the new ppf bottle to that of the present glass bact/alert pf bottle for the recovery of microorganisms as well as for the time to detection of growth in samples of blood obtained for culture from children. we found that the ppf and pf bottles were comparable for recovery of microorganisms and that th ... | 2005 | 15635011 |
| vertically acquired neonatal citrobacter brain abscess - case report and review of the literature. | vertically acquired citrobacter meningitis in the neonate is very rare and carries a very high mortality and morbidity. overall, approximately 30% of neonates with citrobacter meningitis die and 50% sustain some damage to the cns. the authors describe a case of a newborn with citrobacter koseri meningitis with multiple brain abscesses, with a successful outcome following multiple burr-hole aspirations and prolonged antibiotic therapy. an aggressive surgical approach combined with intravenous ant ... | 2005 | 15749429 |
| mimivirus in pneumonia patients. | mimivirus, the largest virus known to date, is an amebal pathogen-like legionella sp. when mimivirus was used as an antigen in a microimmunofluorescense assay, seroconversion was found in patients with both community- and hospital-acquired pneumonia. mimivirus dna was found in respiratory samples of a patient with hospital-acquired pneumonia. | 2005 | 15757563 |
| presence of multidrug-resistant enteric bacteria in dairy farm topsoil. | in addition to human and veterinary medicine, antibiotics are extensively used in agricultural settings, such as for treatment of infections, growth enhancement, and prophylaxis in food animals, leading to selection of drug and multidrug-resistant bacteria. to help circumvent the problem of bacterial antibiotic resistance, it is first necessary to understand the scope of the problem. however, it is not fully understood how widespread antibiotic-resistant bacteria are in agricultural settings. th ... | 2005 | 15778307 |
| novel tem-type extended-spectrum beta-lactamase, tem-134, in a citrobacter koseri clinical isolate. | a new natural tem derivative with extended-spectrum beta-lactamase activity, tem-134, was identified in a ceftazidime-resistant clinical isolate of citrobacter koseri. compared to tem-1, tem-134 contains the following mutations: q39k, e104k, r164h, and g238s. the bla(tem-134) gene was not transferable by conjugation and, apparently, was chromosomally encoded. expression studies with escherichia coli revealed efficient cefotaximase and ceftazidimase activity for tem-134. | 2005 | 15793140 |
| identification of clinically relevant viridans streptococci by an oligonucleotide array. | viridans streptococci (vs) are common etiologic agents of subacute infective endocarditis and are capable of causing a variety of pyogenic infections. many species of vs are difficult to differentiate by phenotypic traits. an oligonucleotide array based on 16s-23s rrna gene intergenic spacer (its) sequences was developed to identify 11 clinically relevant vs. these 11 species were streptococcus anginosus, s. constellatus, s. gordonii, s. intermedius, s. mitis, s. mutans, s. oralis, s. parasangui ... | 2005 | 15814960 |
| efficient discrimination within a corynebacterium diphtheriae epidemic clonal group by a novel macroarray-based method. | a large diphtheria epidemic in the 1990s in russia and neighboring countries was caused by a clonal group of closely related corynebacterium diphtheriae strains (ribotypes sankt-peterburg and rossija). in the recently published complete genome sequence of c. diphtheriae strain nctc13129, representative of the epidemic clone (a. m. cerdeno-tarraga et al., nucleic acids res. 31:6516-6523, 2003), we identified in silico two direct repeat (dr) loci 39 kb downstream and 180 kb upstream of the oric re ... | 2005 | 15814981 |
| dizygotic twins discordant for early-onset citrobacter koseri and group b streptococcal sepsis. | early-onset neonatal sepsis is usually a multisystem fulminant illness with prominent respiratory symptoms, and typically the infant has acquired the organism from the maternal genital tract during the intrapartum period. in this article, we report a rare case of dizygotic twins where each individual suffered early-onset sepsis caused by a different pathogen. group b streptococcal (gbs) sepsis was diagnosed in twin a 1 day after birth; sepsis and meningitis caused by citrobacter koseri was diagn ... | 2005 | 15959606 |
| comparative recovery of microorganisms from bact/alert plastic and glass fa and fn blood culture bottles. | biomerieux, inc., has recently introduced plastic bottles to replace glass bottles for use in the bact/alert blood culture system. we compared the performance of the plastic to the glass bottles in a large clinical evaluation. two blood cultures were collected from each patient, one using glass fa (aerobic) and fn (anaerobic) bottles and one using plastic fa and fn bottles. of the 4,040 sets of four bottles collected, 3,110 contained the recommended 8 to 12 ml of blood, yielding 524 microorganis ... | 2005 | 16000442 |
| enhanced culture detection of citrobacter koseri from cerebrospinal fluid in bactec. | 2005 | 16094244 | |
| multidrug-resistant pseudomonas aeruginosa strain that caused an outbreak in a neurosurgery ward and its aac(6')-iae gene cassette encoding a novel aminoglycoside acetyltransferase. | we characterized multidrug-resistant pseudomonas aeruginosa strains isolated from patients involved in an outbreak of catheter-associated urinary tract infections that occurred in a neurosurgery ward of a hospital in sendai, japan. pulsed-field gel electrophoresis of spei-, xbai-, or hpai-digested genomic dnas from the isolates revealed that clonal expansion of a p. aeruginosa strain designated imcj2.s1 had occurred in the ward. this strain possessed broad-spectrum resistance to aminoglycosides, ... | 2005 | 16127047 |
| regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the asia-pacific region (sentry 1998-2002). | we examined the prevalence of extended-spectrum beta-lactamase (esbl)-producing strains of klebsiella pneumoniae, klebsiella oxytoca, escherichia coli, proteus mirabilis, citrobacter koseri, and salmonella spp. that were isolated as part of the sentry asia-pacific surveillance program between 1998 and 2002. during the study period, a total of 6,388 strains were gathered from 17 medical centers in 7 countries and examined for esbl production and hyperproduction of k. oxytoca chromosomal k1 beta-l ... | 2005 | 16165001 |
| evaluation of a rapid direct assay for identification of bacteria and the mec a and van genes from positive-testing blood cultures. | we performed the first evaluation of a dna strip assay (genotype blood culture; hain lifescience, nehren, germany) for the detection of the most relevant bacterial sepsis pathogens directly from positive bactec blood culture bottles (becton dickinson, heidelberg, germany). the test comprises two panels, one for the direct species identification of important gram-positive cocci and the other for gram-negative rods. additionally, detection of the mec a and the van genes are implemented. the genoty ... | 2005 | 16207992 |
| enteroaggregative escherichia coli isolated from chinese diarrhea patients with high-pathogenicity island of yersinia is involved in synthesis of siderophore yersiniabactin. | to investigate the distribution of 12 high-pathogenicity island (hpi) genes and the relation between hpi genes and expression of yersiniabactin (ybt) in enteroaggregative e.coli (eaggec) isolated from chinese diarrhea patients. | 2005 | 16270391 |
| culture-independent characterization of the microbiota of the ant lion myrmeleon mobilis (neuroptera: myrmeleontidae). | ant lions are insect larvae that feed on the liquefied internal components of insect prey. prey capture is assisted by the injection of toxins that are reportedly derived from both the insect and bacterial symbionts. these larvae display interesting gut physiology where the midgut is not connected to the hindgut, preventing elimination of solid waste until adulthood. the presence of a discontinuous gut and the potential involvement of bacteria in prey paralyzation suggest an interesting microbia ... | 2005 | 16332874 |
| use of several inducer and substrate antibiotic combinations in a disk approximation assay format to screen for ampc induction in patient isolates of pseudomonas aeruginosa, enterobacter spp., citrobacter spp., and serratia spp. | two-hundred consecutive, single patient isolates of enterobacter spp., serratia spp., citrobacter spp., and pseudomonas aeruginosa were evaluated for ampc production using a variety of inducer-substrate antibiotic combinations in a disk approximation format. the combinations examined included cefoxitin-piperacillin, imipenem-cefotaxime, imipenem-ceftazidime, imipenem-piperacillin-tazobactam, and imipenem-cefoxitin. all isolates were also screened for the presence of extended-spectrum beta-lactam ... | 2005 | 16333080 |
| peritumoral citrobacter koseri abscess associated with parasagittal meningioma. | this is the second report of a citrobacter-associated brain abscess in an adult and the first report of its association with an intradural tumor. excluding those associated with trauma, neurosurgical procedures, and proximity to the skull base, only seven other cases of abscesses associated with intracranial tumors have been published. five of seven tumor-associated abscesses with a microbiological diagnosis involved gram-negative bacteria, a finding that may indicate a predilection of these mic ... | 2005 | 17152669 |
| [nationwide surveillance of parenteral antibiotics containing meropenem activities against clinically isolated strains in 2004]. | the antibacterial activity of meropenem (mepm) and other parenteral antibiotics against clinical isolates of 907 strains of gram-positive bacteria, 1790 strains of gram-negative bacteria, and 192 strains of anaerobic bacteria obtained from 30 medical institutions during 2004 was measured. the results were as follows; 1. mic90 of mepm for almost all of enterobacteriaceae and haemophilus influenzae were 4-fold to 32-fold lower than those of other carbapenems. mepm was more active than other carbap ... | 2005 | 16521347 |
| a robotic dna purification protocol and real-time pcr for the detection of enterobacter sakazakii in powdered infant formulae. | enterobacter sakazakii is the causative agent of rare but severe food-borne infections associated with meningitis, necrotizing enterocolitis and sepsis in infants. rehydrated powdered infant formulae have been implicated as the source of infection in several outbreaks and sporadic cases. in this work, a real time fluorescence resonance energy transfer pcr assay incorporating an internal amplification control (iac) was developed for the specific detection of e. sakazakii in foods. performance of ... | 2006 | 17166252 |
| qnrb, another plasmid-mediated gene for quinolone resistance. | a novel plasmid-mediated quinolone resistance gene, qnrb, has been discovered in a plasmid encoding the ctx-m-15 beta-lactamase from a klebsiella pneumoniae strain isolated in south india. it has less than 40% amino acid identity with the original qnr (now qnra) gene or with the recently described qnrs but, like them, codes for a protein belonging to the pentapeptide repeat family. strains with qnrb demonstrated low-level resistance to all quinolones tested. the gene has been cloned in an expres ... | 2006 | 16569827 |
| quantitative real-time legionella pcr for environmental water samples: data interpretation. | quantitative legionella pcrs targeting the 16s rrna gene (specific for the genus legionella) and the mip gene (specific for the species legionella pneumophila) were applied to a total of 223 hot water system samples (131 in one laboratory and 92 in another laboratory) and 37 cooling tower samples (all in the same laboratory). the pcr results were compared with those of conventional culture. 16s rrna gene pcr results were nonquantifiable for 2.8% of cooling tower samples and up to 39.1% of hot wa ... | 2006 | 16597985 |
| emergence of an invasive clone of nontoxigenic corynebacterium diphtheriae in the urban poor population of vancouver, canada. | invasive disease due to corynebacterium diphtheriae is rare in north america. here we describe the emergence of a predominant clone of a nontoxigenic strain of c. diphtheriae in the impoverished population of vancouver's downtown core. this clone has caused significant morbidity and contributed to at least two deaths. over a 5-year period, seven cases of bacteremia due to c. diphtheriae were detected in patients admitted to vancouver hospitals. injection drug use, diabetes mellitus, skin coloniz ... | 2006 | 16672385 |
| trends in production of extended-spectrum beta-lactamases among enterobacteria of medical interest: report of the second italian nationwide survey. | results of a 2003 survey carried out in italy to evaluate the prevalence of extended-spectrum beta-lactamase (esbl)-producing enterobacteria are presented. eleven italian microbiology laboratories investigated 9,076 consecutive nonreplicate isolates (inpatients, 6,850; outpatients, 2,226). esbl screening was performed by mic data analysis. confirmation was obtained using the double-disk synergy test and the combination disk test based on clsi methodology. esbl determinants were investigated by c ... | 2006 | 16672390 |
| panophthalmitis secondary to infection with citrobacter koseri. | 2006 | 16691260 | |
| adhesive properties of enterobacter sakazakii to human epithelial and brain microvascular endothelial cells. | enterobacter sakazakii is an opportunistic pathogen that has been associated with sporadic cases and outbreaks causing meningitis, necrotizing enterocolitis and sepsis especially in neonates. however, up to now little is known about the mechanisms of pathogenicity in e. sakazakii. a necessary state in the successful colonization, establishment and ultimately production of disease by microbial pathogens is the ability to adhere to host surfaces such as mucous membranes, gastric and intestinal epi ... | 2006 | 16800879 |
| segmental tracheal dysplasia in a mixed breed dog. | a 6-month-old, spayed female, mixed breed dog was referred for respiratory difficulty. radiographic and bronchoscopic evaluations showed tracheal narrowing from the thoracic inlet to its bifurcation. under anesthesia, the trachea ruptured and the dog died. microscopic evaluation revealed underlying segmental tracheal and bronchial cartilaginous malformation (dysplasia). | 2006 | 17078250 |
| [clinical results of resection arthroplasty for infected shoulder arthroplasty]. | infection is a rare complication of shoulder arthroplasty. various therapeutic solutions have been proposed: antibiotics alone, one-stage or two-stage reimplantation, surgical or arthroscopic cleaning without prosthesis removal, scapulohumeral arthrodesis or simple arthroscopic resection. we evaluated the mid-term clinical outcome after resection arthroplasty for the treatment of infected shoulder arthroplasty. | 2006 | 17088753 |
| flip influences citrobacter koseri macrophage uptake, cytokine expression and brain abscess formation in the neonatal rat. | citrobacter koseri causes neonatal meningitis frequently complicated with multiple brain abscesses. during c. koseri central nervous system infection in the neonatal rat model, previous studies have documented many bacteria-filled macrophages within the neonatal rat brain and abscesses. previous studies have also shown that c. koseri is taken up by, survives phagolysosomal fusion and replicates in macrophages in vitro and in vivo. in this study, in order to elucidate genetic and cellular factors ... | 2006 | 17108264 |
| ai-3 synthesis is not dependent on luxs in escherichia coli. | the quorum-sensing (qs) signal autoinducer-2 (ai-2) has been proposed to promote interspecies signaling in a broad range of bacterial species. ai-2 is spontaneously derived from 4,5-dihydroxy-2,3-pentanedione that, along with homocysteine, is produced by cleavage of s-adenosylhomocysteine (sah) and s-ribosylhomocysteine by the pfs and luxs enzymes. numerous phenotypes have been attributed to ai-2 qs signaling using luxs mutants. we have previously reported that the luxs mutation also affects the ... | 2006 | 16885435 |
| fishmeal extract bile salt lactose agar--a differential medium for enteric bacteria. | fishmeal extract bile salt lactose agar (febla), a new differential medium for enteric bacteria was developed and evaluated for its ability to grow and differentiate lactose fermenters (lf) from non-lactose fermenters (nlf) in comparison with macconkeys agar. performance of febla was at par with the latter. on febla medium, the contrast between lf and nlf colonies was pronounced and klebsiella pneumoniae produced more mucoid colonies than on macconkeys agar (hi media). unlike macconkeys agar, a ... | 2006 | 16924840 |
| mobilizable incq-related plasmid carrying a new quinolone resistance gene, qnrs2, isolated from the bacterial community of a wastewater treatment plant. | plasmid-encoded quinolone resistance was previously reported for different bacteria isolated from patients not only in the united states and asia but also in europe. here we describe the isolation, by applying a new selection strategy, of the quinolone resistance plasmid pgnb2 from an activated sludge bacterial community of a wastewater treatment plant in germany. the hypersensitive escherichia coli strain kam3 carrying a mutation in the multidrug efflux system genes acrab was transformed with t ... | 2006 | 16940104 |
| isolation of a lactobacillus salivarius strain and purification of its bacteriocin, which is inhibitory to campylobacter jejuni in the chicken gastrointestinal system. | we evaluated anti-campylobacter jejuni activity among >1,200 isolates of different lactic acid bacteria. lactobacillus salivarius strain nrrl b-30514 was selected for further study. the cell-free, ammonium sulfate precipitate from the broth culture was termed the crude antimicrobial preparation. ten microliters of the crude preparation created a zone of c. jejuni growth inhibition, and growth within the zone resumed when the crude preparation was preincubated with proteolytic enzymes. bacterioci ... | 2006 | 16940109 |
| genetic environment of quinolone resistance gene qnrb2 in a complex sul1-type integron in the newly described salmonella enterica serovar keurmassar. | a qnrb2 determinant was described for a new complex sul1-type integron from salmonella enterica serovar keurmassar. the genetic structure contained two class 1 integrons surrounding two common regions (crs) separated by a partial 3' conserved segment. the qnrb2 gene is adjacent to the first cr. | 2006 | 16940131 |
| phenotypic detection of carbapenem-susceptible metallo-beta-lactamase-producing gram-negative bacilli in the clinical laboratory. | rapid detection of metallo-beta-lactamase (mbl)-producing gram-negative pathogens is critical to prevent their widespread dissemination. thus far, no standardized phenotypic method is available, and previously reported techniques have poor sensitivity for detecting carbapenem-susceptible mbl-carrying isolates, an increasingly described phenomenon. we developed a phenotypic detection method using both a double-disk synergy test and a combined-disk test with imipenem and 292 microg edta on one aga ... | 2006 | 16954239 |
| prevalence of newer beta-lactamases in gram-negative clinical isolates collected in the united states from 2001 to 2002. | newer beta-lactamases such as extended-spectrum beta-lactamases (esbls), transferable ampc beta-lactamases, and carbapenemases are associated with laboratory testing problems of false susceptibility that can lead to inappropriate therapy for infected patients. because there appears to be a lack of awareness of these enzymes, a study was conducted during 2001 to 2002 in which 6,421 consecutive, nonduplicate clinical isolates of aerobically growing gram-negative bacilli from patients at 42 intensi ... | 2006 | 16954267 |
| detection of enterobacter sakazakii in dried infant milk formula by cationic-magnetic-bead capture. | enterobacter sakazakii has been associated with life-threatening infections in premature low-birth-weight infants. contaminated infant milk formula (imf) has been implicated in cases of e. sakazakii meningitis. quick and sensitive methods to detect low-level contamination sporadically present in imf preparations would positively contribute towards risk reduction across the infant formula food chain. here we report on the development of a simple method, combining charged separation and growth on ... | 2006 | 16957259 |
| ft-ir microspectroscopy for early identification of some clinically relevant pathogens. | to investigate the potentials and limitations of fourier transform-infrared (ft-ir) microspectroscopy as a tool to identify, at the level of microcolonies, pathogenic bacteria frequently isolated in the clinical environment. | 2006 | 16968290 |
| diffuse pneumocephalus in neonatal citrobacter meningitis. | pneumocephalus, intracranial air or gas collection, associated with neonatal meningitis is extremely rare. we report the first case in the united states and the second case in the world of intracranial gas accumulation in a neonate with citrobacter koseri meningitis. the clinical presentation was acute with pneumocephalus demonstrated by cranial sonography and computed tomography. the clinical course was fatal despite the prompt administration of antibiotics. | 2006 | 17000783 |
| two-center collaborative evaluation of performance of the bd phoenix automated microbiology system for identification and antimicrobial susceptibility testing of gram-negative bacteria. | the performance of the bd phoenix automated microbiology system (bd diagnostic systems, sparks, md) was assessed for identification (id) and antimicrobial susceptibility testing (ast) of the majority of clinically encountered bacterial isolates in a european collaborative two-center trial. a total of 494 bacterial isolates including various species of the enterobacteriaceae and 110 nonfermentative gram-negative bacteria were investigated: of these, 385 were single patient isolates, and 109 were ... | 2006 | 17005752 |
| pcr classification of ctx-m-type beta-lactamase genes identified in clinically isolated gram-negative bacilli in japan. | of 1,456 strains isolated from 2001 to 2003 demonstrating resistance to either oxyimino-cephalosporin, 317 strains, isolated in 57 of 132 clinical facilities, were found to harbor bla(ctx-m) genes by pcr. fifty-seven, 161, and 99 strains harbored bla(ctx-m) genes belonging to the bla(ctx-m-1), bla(ctx-m-2), and bla(ctx-m-9) clusters, respectively. | 2006 | 16436748 |
| characterization of the chromosomal class a beta-lactamase cko from citrobacter koseri. | the gene bla(cko) encoding the chromosomal class a beta-lactamase of citrobacter koseri was cloned and sequenced. cko was found to display only 41% identity with sed-1 from citrobacter sedlakii and 36% with cdia from citrobacter amalonaticus (formerly citrobacter diversus). no transcriptional regulator was found upstream from bla(cko). silent and missense mutations were detected in four bla(cko) genes amplified from different c. koseri clinical isolates, but the cko variants displayed identical ... | 2006 | 16445758 |
| use of electrochemical dna biosensors for rapid molecular identification of uropathogens in clinical urine specimens. | we describe the first species-specific detection of bacterial pathogens in human clinical fluid samples using a microfabricated electrochemical sensor array. each of the 16 sensors in the array consisted of three single-layer gold electrodes-working, reference, and auxiliary. each of the working electrodes contained one representative from a library of capture probes, each specific for a clinically relevant bacterial urinary pathogen. the library included probes for escherichia coli, proteus mir ... | 2006 | 16455913 |
| ameba-associated microorganisms and diagnosis of nosocomial pneumonia. | to elucidate the role of ameba-associated microorganisms (aams) as etiologic agents of pneumonia, we screened for legionella spp., parachlamydia acanthamoeba, afipia sp., bosea spp., bradyrhizobium spp., mesorhizobium amorphae, rasbo bacterium, azorhizobium caulinodans, acanthamoeba polyphaga mimivirus, and conventional microorganisms in 210 pneumonia patients in intensive-care units by using culture, polymerase chain reaction, and serologic testing. these resulted in 59 diagnoses in 40 patients ... | 2006 | 16494750 |
| a nosocomial outbreak due to novel ctx-m-2-producing strains of citrobacter koseri in a hematological ward. | 2006 | 16495644 | |
| evaluation of the phoenix 100 id/ast system and nid panel for identification of enterobacteriaceae, vibrionaceae, and commonly isolated nonenteric gram-negative bacilli. | the phoenix 100 id/ast system (becton dickinson co., sparks, md.) is an automated system for the identification and antimicrobial susceptibility testing of bacterial isolates. this system with its negative identification (nid) panel was evaluated for its accuracy in the identification of 507 isolates of the family enterobacteriaceae, 57 other nonenteric gram-negative isolates that are commonly isolated in clinical microbiology laboratories, and 138 isolates of the family vibrionaceae. all of the ... | 2006 | 16517878 |
| risk factors for umbilical cord infection among newborns of southern nepal. | although umbilical cord infection contributes to neonatal mortality and morbidity and risk can be reduced with topical chlorhexidine, behavioral or other factors associated with cord infection in low-resource settings have not been examined. data on potential risk factors for omphalitis were collected during a community-based, umbilical cord care trial in nepal during 2002-2005. newborns were evaluated in the home for signs of umbilical cord infection (pus, redness, and swelling). omphalitis was ... | 2006 | 17065275 |
| risk factors for umbilical cord infection among newborns of southern nepal. | although umbilical cord infection contributes to neonatal mortality and morbidity and risk can be reduced with topical chlorhexidine, behavioral or other factors associated with cord infection in low-resource settings have not been examined. data on potential risk factors for omphalitis were collected during a community-based, umbilical cord care trial in nepal during 2002-2005. newborns were evaluated in the home for signs of umbilical cord infection (pus, redness, and swelling). omphalitis was ... | 2006 | 17065275 |
| prevalence and genetic analysis of plasmid-mediated quinolone resistance determinants qnra and qnrs in enterobacteriaceae isolates from a french university hospital. | the spread of plasmid-mediated quinolone resistance determinants qnra and qnrs was evaluated in a collection of 186 extended-spectrum beta-lactamase (esbl)-positive enterobacterial isolates from 2002 to 2005 and 185 nalidixic acid-resistant strains isolated during the first 6 months of 2005 at the bicêtre hospital, france. out of these 186 esbl-positive isolates, 2.2 and 1.6% carried a qnra1 and a qnrs1 determinant, respectively. the esbls associated with qnra1 were veb-1, shv-12, and ctx-m-1, w ... | 2006 | 16982792 |
| decreases in procalcitonin and c-reactive protein are strong predictors of survival in ventilator-associated pneumonia. | this study sought to assess the prognostic value of the kinetics of procalcitonin (pct), c-reactive protein (crp) and clinical scores (clinical pulmonary infection score (cpis), sequential organ failure assessment (sofa)) in the outcome of ventilator-associated pneumonia (vap) at an early time point, when adequacy of antimicrobial treatment is evaluated. | 2006 | 16956405 |
| evaluation of the new vitek 2 extended-spectrum beta-lactamase (esbl) test for rapid detection of esbl production in enterobacteriaceae isolates. | extended-spectrum beta-lactamases (esbls) are a large, rapidly evolving group of enzymes that confer resistance to oxyimino cephalosporins and monobactams and are inhibited by clavulanate. rapid reliable detection of esbl production is a prerequisite for successful infection management and for monitoring resistance trends and implementation of intervention strategies. we evaluated the performance of the new vitek 2 esbl test system (biomérieux, inc, hazelwood, mo.) in the identification of esbl- ... | 2006 | 16954257 |
| widely distributed and predominant ctx-m extended-spectrum beta-lactamases in amsterdam, the netherlands. | three hundred sixty enterobacteriaceae and nonfermenting gram-negative bacilli, isolated during one week in may 2004 at five hospitals in amsterdam, the netherlands, were evaluated for the presence of extended-spectrum beta-lactamases (esbls). a prevalence of 7.8% was found, in contrast to the 1% observed in 1997. ctx-m esbls dominated, and four types were identified in 18 isolates. | 2006 | 16891530 |
| role of staged endoprosthetic revision with flap cover for limb salvage in endoprosthetic failure. | endoprosthetic replacement (epr) is commonly required for limb salvage in bone malignancies. endoprosthetic failure is a term used to denote mechanical failure or infection usually requiring removal of the prosthesis. treatment of infection consists of epr revision with or without placement of a temporary spacer. flap cover (either local or free) may be required if the overlying soft tissues are of concern. it is claimed that the investment of the endoprosthesis in well-vacularised soft tissue f ... | 2006 | 16607554 |
| prosthetic vascular graft infection: a multi-center review of surgical management. | a multi-center retrospective review of major prosthetic graft infection outcomes was undertaken to determine graft preservation and limb salvage rates. the management of infected prosthetic vascular grafts continues to be controversial. the purpose of this study was to review the surgical management of major extracavitary prosthetic vascular graft infections and to correlate the outcomes on the basis of bacteriology and grade. the change in patient population seen by vascular surgeons and the re ... | 2007 | 18299723 |
| prosthetic vascular graft infection: a multi-center review of surgical management. | a multi-center retrospective review of major prosthetic graft infection outcomes was undertaken to determine graft preservation and limb salvage rates. the management of infected prosthetic vascular grafts continues to be controversial. the purpose of this study was to review the surgical management of major extracavitary prosthetic vascular graft infections and to correlate the outcomes on the basis of bacteriology and grade. the change in patient population seen by vascular surgeons and the re ... | 2007 | 18299723 |
| maternal serum concentrations of the chemokine cxcl10/ip-10 are elevated in acute pyelonephritis during pregnancy. | acute pyelonephritis is one of the most frequent medical complications of pregnancy, as well as a common cause of antepartum hospitalization. interferon (ifn)-gamma inducible protein, cxcl10/ip-10, is a member of the cxc chemokine family with pro-inflammatory and anti-angiogenic properties. the purpose of this study was to determine whether maternal serum concentrations of cxcl10/ip-10 change in patients with acute pyelonephritis during pregnancy. | 2007 | 17763275 |
| sonographic findings in bacterial meningitis in neonates and young infants. | cranial sonography plays an important role in the initial evaluation of infants with suspected bacterial meningitis and in monitoring for complications of the disease. echogenic widening of the brain sulci, meningeal thickening and hyperemia suggest the diagnosis in an at-risk population. sonography can identify the presence of extra-axial fluid collections, and color doppler sonography can be very helpful in differentiating benign enlargement of subarachnoid spaces from subdural effusions. intr ... | 2007 | 17611750 |
| sonographic findings in bacterial meningitis in neonates and young infants. | cranial sonography plays an important role in the initial evaluation of infants with suspected bacterial meningitis and in monitoring for complications of the disease. echogenic widening of the brain sulci, meningeal thickening and hyperemia suggest the diagnosis in an at-risk population. sonography can identify the presence of extra-axial fluid collections, and color doppler sonography can be very helpful in differentiating benign enlargement of subarachnoid spaces from subdural effusions. intr ... | 2007 | 17611750 |
| reevaluation of clinical and laboratory standards institute disk diffusion breakpoints for tetracyclines for testing enterobacteriaceae. | we reevaluated enterobacteriaceae disk diffusion breakpoints for the tetracyclines published in the clinical and laboratory standards institute (clsi) document m100-s16, which were (susceptible/resistant) >or=19 mm/<or=14 mm for tetracycline, >or=16 mm/<or=12 mm for doxycycline, and >or=19 mm/<or=14 mm for minocycline. a collection of 504 recent clinical isolates of enterobacteriaceae were tested against these tetracycline compounds by disk diffusion and broth microdilution methods according to ... | 2007 | 17360844 |
| immunological system status and the appearance of respiratory system disturbances in thymectomized patients. | adult-onset thymoma may be responsible for several diseases, such as pure red cell aplasia, myasthenia gravis, and immunodeficiency (good's syndrome). thymectomy does not always improve the patient's condition, and may even produce additional symptoms. its pathogenesis is still not entirely understood, but autoimmunological processes and bone marrow defect are the most frequently suggested. | 2007 | 17277895 |
| comparative evaluation of automated reading versus visual interpretation with the bbl crystal enteric/nonfermenter identification system in a clinical setting. | 2007 | 17520304 | |
| some bacteria degrade explosives, others prefer boiling methanol. | 2007 | 17991022 | |
| zoo animals as reservoirs of gram-negative bacteria harboring integrons and antimicrobial resistance genes. | a total of 232 isolates of gram-negative bacteria were recovered from mammals, reptiles, and birds housed at asa zoological park, hiroshima prefecture, japan. forty-nine isolates (21.1%) showed multidrug resistance phenotypes and harbored at least one antimicrobial resistance gene. pcr and dna sequencing identified class 1 and class 2 integrons and many beta-lactamase-encoding genes, in addition to a novel ampc beta-lactamase gene, bla(cmy-26). furthermore, the plasmid-mediated quinolone resista ... | 2007 | 17720829 |
| evaluation of the merlin micronaut system for rapid direct susceptibility testing of gram-positive cocci and gram-negative bacilli from positive blood cultures. | bloodstream infections are life-threatening conditions which require the timely initiation of appropriate antimicrobial therapy. we evaluated the automated merlin micronaut system for rapid direct microtiter broth antimicrobial susceptibility testing (ast) of gram-positive cocci and gram-negative bacilli from bactec 9240 bottles with positive blood cultures in comparison to the standard method for the merlin micronaut system. this prospective study was conducted under routine working conditions ... | 2007 | 17202283 |
| increased serum iga and igm against lps of enterobacteria in chronic fatigue syndrome (cfs): indication for the involvement of gram-negative enterobacteria in the etiology of cfs and for the presence of an increased gut-intestinal permeability. | there is now evidence that chronic fatigue syndrome (cfs) is accompanied by immune disorders and by increased oxidative stress. the present study has been designed in order to examine the serum concentrations of iga and igm to lps of gram-negative enterobacteria, i.e. hafnia alvei; pseudomonas aeruginosa, morganella morganii, proteus mirabilis, pseudomonas putida, citrobacter koseri, and klebsiella pneumoniae in cfs patients, patients with partial cfs and normal controls. we found that the preva ... | 2007 | 17007934 |
| sensitive quantitative detection of commensal bacteria by rrna-targeted reverse transcription-pcr. | a sensitive rrna-targeted reverse transcription-quantitative pcr (rt-qpcr) method was developed for exact and sensitive enumeration of subdominant bacterial populations. using group- or species-specific primers for 16s or 23s rrna, analytical curves were constructed for escherichia coli, enterococcus faecalis, staphylococcus aureus, clostridium perfringens, and pseudomonas aeruginosa, and the threshold cycle value was found to be linear up to an rna amount of 10(-3) cell per rt-pcr. the number o ... | 2007 | 17071791 |
| sensitive quantitative detection of commensal bacteria by rrna-targeted reverse transcription-pcr. | a sensitive rrna-targeted reverse transcription-quantitative pcr (rt-qpcr) method was developed for exact and sensitive enumeration of subdominant bacterial populations. using group- or species-specific primers for 16s or 23s rrna, analytical curves were constructed for escherichia coli, enterococcus faecalis, staphylococcus aureus, clostridium perfringens, and pseudomonas aeruginosa, and the threshold cycle value was found to be linear up to an rna amount of 10(-3) cell per rt-pcr. the number o ... | 2007 | 17071791 |
| comparison of media for the isolation of enterobacter sakazakii. | enterobacter sakazakii is associated with neonatal infections and is occasionally present at low levels (<1 cfu/g) in powdered infant formula milk (ifm). it has been previously reported that some e. sakazakii strains do not grow in standard media for enterobacteriaceae and coliform bacteria; therefore, a reliable method is needed for recovery of the organism. three e. sakazakii enrichment broths-enterobacteriaceae enrichment broth (ee), e. sakazakii selective broth (essb), and modified lauryl su ... | 2007 | 17071794 |
| comparison of media for the isolation of enterobacter sakazakii. | enterobacter sakazakii is associated with neonatal infections and is occasionally present at low levels (<1 cfu/g) in powdered infant formula milk (ifm). it has been previously reported that some e. sakazakii strains do not grow in standard media for enterobacteriaceae and coliform bacteria; therefore, a reliable method is needed for recovery of the organism. three e. sakazakii enrichment broths-enterobacteriaceae enrichment broth (ee), e. sakazakii selective broth (essb), and modified lauryl su ... | 2007 | 17071794 |
| novel ambler class a beta-lactamase lap-1 and its association with the plasmid-mediated quinolone resistance determinant qnrs1. | the plasmid-mediated quinolone resistance determinant qnrs1 was identified in non-clonally related enterobacter cloacae isolates in association with a transferable narrow-spectrum beta-lactam resistance marker. cloning experiments allowed the identification of a novel ambler class a beta-lactamase, named lap-1. it shares 62 and 61% amino acid identity with the most closely related beta-lactamases, tem-1 and shv-1, respectively. it has a narrow-spectrum hydrolysis of beta-lactams and is strongly ... | 2007 | 17116662 |
| novel ambler class a beta-lactamase lap-1 and its association with the plasmid-mediated quinolone resistance determinant qnrs1. | the plasmid-mediated quinolone resistance determinant qnrs1 was identified in non-clonally related enterobacter cloacae isolates in association with a transferable narrow-spectrum beta-lactam resistance marker. cloning experiments allowed the identification of a novel ambler class a beta-lactamase, named lap-1. it shares 62 and 61% amino acid identity with the most closely related beta-lactamases, tem-1 and shv-1, respectively. it has a narrow-spectrum hydrolysis of beta-lactams and is strongly ... | 2007 | 17116662 |
| a rare case of lethal retroperitoneal abscess caused by citrobacter koseri. | retroperitoneal abscesses are very uncommon clinical conditions. the characteristically vague symptomatology of retroperitoneal abscess and the inherent difficulty of identifying retroperitoneal disease by physical examination contributed to these dismal therapeutic outcomes. we present an unusual case of lethal retroperitoneal abscess, caused by citrobacter diversus(koseri), treated with surgical drainage. citrobacter species have rarely been involved in deep tissue infection and there is no re ... | 2007 | 18025858 |
| antimicrobial-resistant enteric bacteria from dairy cattle. | a study was conducted to understand the descriptive and molecular epidemiology of antimicrobial-resistant gram-negative enteric bacteria in the feces of healthy lactating dairy cattle. gram-negative enteric bacteria resistant to ampicillin, florfenicol, spectinomycin, and tetracycline were isolated from the feces of 35, 8, 5, and 42% of 213 lactating cattle on 74, 39, 9, 26, and 82% of 23 farms surveyed, respectively. antimicrobial-resistant gram-negative bacteria accounted for 5 (florfenicol) t ... | 2007 | 17098918 |
| antimicrobial-resistant enteric bacteria from dairy cattle. | a study was conducted to understand the descriptive and molecular epidemiology of antimicrobial-resistant gram-negative enteric bacteria in the feces of healthy lactating dairy cattle. gram-negative enteric bacteria resistant to ampicillin, florfenicol, spectinomycin, and tetracycline were isolated from the feces of 35, 8, 5, and 42% of 213 lactating cattle on 74, 39, 9, 26, and 82% of 23 farms surveyed, respectively. antimicrobial-resistant gram-negative bacteria accounted for 5 (florfenicol) t ... | 2007 | 17098918 |
| citrobacter infections in a tertiary care hospital in northern india. | this prospective study was carried out to look for the frequency of isolation of citrobacter species from clinical specimens and study their antimicrobial susceptibility pattern. | 2007 | 16815552 |
| evaluation of a new selective chromogenic agar medium for detection of extended-spectrum beta-lactamase-producing enterobacteriaceae. | a novel chromogenic agar medium (esbl-bx; biomérieux, marcy l'etoile, france) was compared to macconkey agar supplemented with 2 mg ceftazidime/liter (mckc) for the selective isolation and presumptive identification of extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae directly from clinical samples. of a total of 644 clinical specimens (including 551 fecal samples), 496 yielded no growth and 148 yielded growth on one or both media. overall, 44 esbl-producing enterobacteriaceae ... | 2007 | 17182756 |
| evaluation of a new selective chromogenic agar medium for detection of extended-spectrum beta-lactamase-producing enterobacteriaceae. | a novel chromogenic agar medium (esbl-bx; biomérieux, marcy l'etoile, france) was compared to macconkey agar supplemented with 2 mg ceftazidime/liter (mckc) for the selective isolation and presumptive identification of extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae directly from clinical samples. of a total of 644 clinical specimens (including 551 fecal samples), 496 yielded no growth and 148 yielded growth on one or both media. overall, 44 esbl-producing enterobacteriaceae ... | 2007 | 17182756 |
| multicenter beta trial of the genexpert enterovirus assay. | the genexpert dx system (cepheid, sunnyvale, ca) is a fully integrated and automated nucleic acid sample preparation, amplification, and real-time detection system. it consists of an instrument, a personal computer, and disposable fluidic cartridges. the analytical sensitivity and specificity of the genexpert enterovirus assay (gxea) were determined with a panel of 63 different enterovirus serotypes and 24 other microorganisms, respectively. the potential for blood, hemoglobin, white blood cells ... | 2007 | 17251395 |
| in vitro and in vivo activities of pd 0305970 and pd 0326448, new bacterial gyrase/topoisomerase inhibitors with potent antibacterial activities versus multidrug-resistant gram-positive and fastidious organism groups. | pd 0305970 and pd 0326448 are new bacterial gyrase and topoisomerase inhibitors (quinazoline-2,4-diones) that possess outstanding in vitro and in vivo activities against a wide spectrum of bacterial species including quinolone- and multidrug-resistant gram-positive and fastidious organism groups. the respective mics (microg/ml) for pd 0305970 capable of inhibiting>or=90% of bacterial strains tested ranged from 0.125 to 0.5 versus staphylococci, 0.03 to 0.06 versus streptococci, 0.25 to 2 versus ... | 2007 | 17261623 |
| characterization of the gene encoding the 16s rrna of enterobacter sakazakii and development of a species-specific pcr method. | the gene encoding the 16s rrna of enterobacter (e.) sakazakii (atcc 29544, plus four strains isolated from powdered infant formula) was studied, and the sequence compared with those of other enterobacteriaceae in aspects of genetic variability. sequence differences between e. sakazakii and other enterobacteriaceae within the hypervariable regions v1, v2, and v3, respectively, were used to develop two pcr methods for e. sakazakii. pcr1 employed a primer pair located in v1/v2, while pcr2 utilized ... | 2007 | 17289198 |
| accelerated in vitro differentiation of blood monocytes into dendritic cells in human sepsis. | summary sepsis-induced immune depression is characterized by infection susceptibility and monocyte early deactivation. because monocytes are precursors for dendritic cells (dc), alterations in their differentiation into dc may contribute to defective immune responses in septic patients. we therefore investigated the ability of monocytes to differentiate into functional dc in vitro in patients undergoing surgery for peritonitis. monocytes from 20 patients collected immediately after surgery (d0), ... | 2007 | 17302891 |
| characteristics of beta-lactamases and their genes (blaa and blab) in yersinia intermedia and y. frederiksenii. | the presence of beta-lactamases in y. enterocolitica has been reported to vary with serovars, biovars and geographical origin of the isolates. an understanding of the beta-lactamases in other related species is important for an overall perception of antibiotic resistance in yersiniae. the objective of this work was to study the characteristics of beta-lactamases and their genes in strains of y. intermedia and y. frederiksenii, isolated from clinical and non-clinical sources in india. | 2007 | 17407578 |