Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| visualization of mitochondrial coupling factor f1(atpase) by freeze-drying. | it is known that the negatively stained preparations of inner mitochondrial membrane display characteristic approximately 9 nm f1 (atpase) knobs projecting from the matrix surface. freeze-etch studies have reported the absence of such knobs from the "etched" surface of the inner mitochondrial membranes. we have demonstrated their presence on the surface of smp (submitochondrial particles) prepared by freeze-drying for transmission electron microscopy. this identification has been substantiated b ... | 1979 | 95168 |
| effects of ovarian hormones on cell membranes in the rat uterus. i. freeze fracture studies of the apical membrane of the liminal epithelium. | freeze fracture techniques have been used to study the apical membrane of cells of the luminal epithelium of the rat uterus under various hormonal regimes. in the ovariectomized but otherwise untreated rat, intramembranous particles (imps) occur at a density of 1395 +/- 122 per micron 2; they appeared spherical and uniformly distributed. after 3 days treatment with estrogen, no change in appearance or density was found, but 3 days of progesterone treatment produced a significant increase in imp ... | 1979 | 95176 |
| isoprinosine increases the antitumor action of interferon. | the association of relatively low doses of interferon with an immunostimulant, isoprinosine, enhanced the antitumor effect of interferon. each mouse was inoculated with 10(6) crocker tumor 180/tg cells. the best results were obtained when both interferon and isoprinosine were injected three times a week for 1 month. under these conditions, the mean survival time increased from 26 days in the controls to 45 days in the interferon-treated group to 64 days when both agents were used. isoprinosine a ... | 1979 | 95187 |
| immunochemical identity of "decidualization-associated protein' and alpha 2 acute-phase macroglobulin in the pregnant rate. | 1979 | 95199 | |
| experimental determination of interacting sequences in ribosomal rna. | 1979 | 95206 | |
| inhibition and stimulation of histamine release by oxatomide. | 1979 | 95250 | |
| chromatographic properties of sephacryl s-300 superfine. | sephacryl s-300 superfine is a new gel filtration medium that consists of allyldextran crosslinked with n,n'-methylenebisacrylamide. it was shown to have a separation range for proteins that extends to 1--2 x 10(6) dalton. the gel filtration properties were characterized by fractionation of human serum and of bovine colostrum. thyroglobulin from pig could be isolated in one step in a very pure form. the flow properties were characterized by the relationship between flow rate and pressure drop. i ... | 1979 | 95254 |
| spontaneous termination of reentry ventricular tachycardia in the late myocardial infarction period: an experimental study in the dog. | forty episodes of induced ventricular tachycardia in the late myocardial infarction period (4-6 days old) were analyzed in 12 dogs in an attempt to identify the possible mechanisms for the termination of reentry tachycardia. multiple epicardial and endocardial composite electrograms were recorded in and around the central ischemic zone of the infarction. during tachycardia, the earliest site of activation was identified in the epicardial surface of the border or normal zone immediately adjacent ... | 1979 | 95291 |
| a rat model (using a semipurified diet) of the fetal alcohol syndrome. | a semipurified liquid diet was used to develop a chronic rat model of the fetal alcohol syndrome. control female rats gained weight normally, reproduced normally, and gave birth to normal litters on this diet. increased neonatal mortality, decreased neonatal weights, and altered sex ratios were observed in offspring of experimental alcoholic animals. preliminary histological results include a mild delay in cell lamination patterns in the cerebral cortex at 4 days postnatal in alcoholic offspring ... | 1979 | 95338 |
| antigenic similarity between squamous cell carcinoma of horn (horn cancer) and normal bovine foetal tissues. | normal bovine foetal (liver and skin) and horn cancer tissue antigens were examined using double diffusion agar gel precipitation and immuno-electrophoretic tests to detect any cross reactivity among them. rabbit horn cancer antisera absorbed with normal bovine liver, skin and horn core epithelium antigens, when tested with foetal skin and liver (4 to 6 months of gestation), revealed the presence of 2 foetal antigens in horn cancer. immuno-chemically 2 of the horn cancer antigens were found to b ... | 1979 | 95358 |
| [adaptation of the cardiac cell to chronic mechanical overload]. | 1979 | 95439 | |
| flow cytometry: general principles and applications to selected studies in tumor biology. | the cell populations derived from normal tissues and solid tumors comprised many different cell types. within each cell type there is a distribution of cells in different phases of the cell cycle and/or metabolic states (ie, differing rates of protein, rna, and other macromolecular syntheses). flow cytometry and companion instrumentation now promise to aid in rapid quantitative analyses of heterogeneous cell populations, thus finding broad applicability in many areas of cancer research and treat ... | 1979 | 95452 |
| [nucleic acids in the liver of rat treated with "e. coli" o 127 lipopolysaccharide (author's transl)]. | the authors have studied the variations of nucleic acids, proteins and histological aspect in the liver of rats, treated with 1 mg of e. coli ) 127 lipopolysaccharide and killed at 24th, 48th, 72th, 96th hour after the inoculation. the endotoxin determines an increase of nucleic acids and a reduction of hepatic proteic contents. the histological observation shows throw-back phenomenons of the hepatocyte with hyperplasy and hypertrophy of kupffer cells at 24th hour, while at following intervals t ... | 1979 | 95476 |
| in vivo and in vitro reactions to antigens of haemophilus influenzae in bronchial obstruction. | the frequency of precipitating antibody to heat-labile (h(1--2) and heat-stable (hcw and hcf) antigens of haemophilus influenzae was determined in patients with asthma, chronic bronchitis, cystic fibrosis and bronchiectasis and compared with that in a control group. this showed that the immune response of asthmatic patients to heat-stable antigens was different from that to the heat-labile antigens. exposure to antigens of h. influenzae is common in all the disease groups. skin test reactions ha ... | 1979 | 95481 |
| the role of eosinophil receptors in the non-genomic response to oestrogens in the uterus. | 1979 | 90751 | |
| protection of rhesus monkeys from lassa virus by immunisation with closely related arenavirus. | 1979 | 90819 | |
| hyperammonaemia, plasma aminoacid imbalance, and blood-brain aminoacid transport: a unified theory of portal-systemic encephalopathy. | it is proposed that hyperammonaemia in liver cirrhosis or after portacaval shunt contributes to plasma neutral aminoacid imbalance and to increased activity of the blood-brain neutral amino-acid transport system. plasma neutral aminoacid concentrations are deranged, partly, but not completely, because ammonia stimulates glucagon secretion; a high rate of gluconeogenesis and hyperinsulinaemia follow. brain uptake of neutral aminoacids rises because ammonia stimulates brain-glutamine synthesis, wh ... | 1979 | 90864 |
| schistosome patterns in egypt. | 1979 | 90881 | |
| splenectomy and karyotypic conversion in chronic myeloid leukaemia. | 1979 | 90884 | |
| stationary potential of the brain: part i. basic studies. | 1979 | 91122 | |
| the structure and evolution of the hla--bw4 and bw6 antigens. | the hla--bw4 and bw6 antigenic determinants have been shown to co-migrate with hla--b determinants on gel-filtration, sucrose density gradient centrifugation and affinity chromatography, using lens culinaris lectin and antibody against human beta 2 microbulin. these and other published data imply that the hla--bw4 and bw6 determinants reside on the same polypeptide chain as other hla--b locus determinants. the implications of this in terms of the evolution of cross reacting groups of antigens at ... | 1979 | 91209 |
| monolayer absorption of human cytotoxic t cells: evidence for clonality. | 1979 | 91211 | |
| [primary liver cell carcinoma, aetiology and clinical picture (author's transl)]. | geographic area, age and sex influence the epidemiology of hepatoma. aetiological factors are aflatoxins, sex hormones, thorotrast, alpha 1-antitrypsin deficiency, immunosuppression, vinylchloride, parasites, cirrhosis of the liver, and the hepatitis-b virus. early diagnosis of the tumour is possible using alpha 1-fetoprotein estimations and modern morphological methods, particularly scintiscanning. tumour resection is therapeutically desirable, while selective chemotherapy remains palliative an ... | 1979 | 91271 |
| glutathione conjugate formation from hexachlorocyclohexane and pentachlorocyclohexene by rat liver in vitro. | 1979 | 91272 | |
| changes in human event related potentials with prolonged delta-9-tetrahydrocannabinol (thc) use. | auditory event related potentials and contingent negative variation (cnv) were recorded in a series of behavioral tasks from 27 hospitalized human volunteers before, early during (1--3 days), late during (10--14 days) and after chronic thc intoxication at two dose levels (70--90 mg/day or 180--210 mg/day in divided doses). twelve additional hospitalized volunteers served as a control group. the n1 component of the auditory event related potential in all tasks was depressed when tested early duri ... | 1979 | 91483 |
| properties of androphilic proteins in cytosols of human benign prostatic hypertrophy. | androphilic proteins in the cytosol from the human benign prostatic hypertrophy are separated into two fractions by sephadex chromatography; void volume fraction and igg fraction which was eluted near the site of higg. in the present study, properties of these two androphilic proteins were compared. association constants of these proteins were in the order of 10(9) m-1. however, the binding capacity of the former was smaller than that of the latter. these two androphilic proteins well bound to n ... | 1979 | 91507 |
| application of human erythrocytes to a radioimmune assay of immune complexes in serum. | 1979 | 91576 | |
| behavior of a surface antigenic determinant of lateral flagella of vibrio parahaemolyticus. | the behavior of a surface antigenic determinant (sa) of lateral flagella of vibrio parahaemolyticus was studied. sa, located on the surface of flagellar filaments, is responsible for h-agglutination and specific for serotype. results of h-agglutination inhibition tests demonstrated that sa could not be detected on the flagellin molecule when the flagellar filaments were dissociated to flagellin monomers by heating or treatment with urea, sodium dodecyl sulfate, hcl, or acetone, although sa could ... | 1979 | 91584 |
| rat liver cytosolic azoreductase. electron transport properties and the mechanism of dicumarol inhibition of the purified enzyme. | 1979 | 91608 | |
| development of new antiallergic drugs (cromolyn sodium, lodoxamide tromethamine). what is the role of cholinergic stimulation in the biphasic dose response? | the antiallergy drugs, cromolyn sodium and lodoxamide tromethamine (u-42,585e) show in vitro dose responses which are bell-shaped or biphasic in mast cells. the nature of the biphasic dose response is poorly understood; however, through the use of specific antagonists, it has been possible to show that at the high concentrations of these drugs leading to enhanced histamine release or multiple high-dose tachyphylaxis, a cholinergic receptor is stimulated in the cell. this receptor is muscarinic i ... | 1979 | 91955 |
| [blood-brain barrier and chemotherapy of experimental brain tumors (author's transl)]. | 1979 | 91993 | |
| synthesis of a 600-nucleotide-long plus-strand dna by virions of moloney murine leukemia virus. | a discrete, 600-nucleotide-long plus-strand dna has been identified among the products of reverse transcription by virions of moloney murine leukemia virus. its polarity was shown by hybridization to minus-strand dna. it appears to be copied from the right end of minus-strand dna because (i) its restriction endonuclease cleavage pattern corresponds to the redundant 600-base segment found at either end of the ultimate double-stranded reverse transcription products, (ii) its synthesis is actinomyc ... | 1979 | 92028 |
| micromplement fixation studies of human plasma prothrombin and purified prothrombin preparations. | 1979 | 92071 | |
| [antigenic and biological characteristics of the a (h1n1) strains that caused the 1977--1978 epidemic]. | by the antigenic specificity of the surface subunits, hemagglutinin and neuraminidase, the influenza virus strains a (h1n1) isolated in 1977--1978 were related but not identical to the a (h1n1) strains circulating in 1950--1952. the a/fm/1/47 strain differed from the a/england/51, a/pan/52 strains and a/ussr/090/77 strain by its antigenic relations with the a/netherland/56 and a/denver/57 strains. biologically, the new a/h1n1/77 strains were similar to the reference strains circulating in 1947-- ... | 1979 | 92100 |
| the effect of organic substrate concentration on activity for microbiological reduction of sulfates. | lactate, pyruvate, malate and alpha-glycerophosphate are excellent sources of energy and structural carbon for desulfovibrio vulgaris. a fully stoichiometric course of the sulfate reduction process has been observed. a simplified equation of the reaction describing the respiration process of the above bacteria in the presence of alpha-glycerophosphate is proposed. | 1979 | 92173 |
| processing of 19 s thyroglobulin in vitro [proceedings]. | 1979 | 92247 | |
| immunologic regulation in pregnancy. | theories to explain the failure of rejection of the fetus by the mother during pregnancy include immunologic privilege of the uterus as a graft site, lack of transplantation antigen expression on the trophoblast, weakening of maternal cellular immunity during pregnancy, and separation of maternal and fetal circulations. evidence for and against each of these theories is discussed. local concentration of a variety of hormones, including human chorionic gonadotropin (hcg), sex steroids, alpha-feto ... | 1979 | 92318 |
| kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, iii. sequence of the two kunitz-type domains inside the native inter-alpha-trypsin inhibitor, its biological aspects and also of its cleavage products. | the human inhibitor hi-14 consists of two kunitz-type domains covalently connected. they are liberated from the human iti by limited tryptic proteolysis. the inhibitor hi-14 is formed via a trypsin inhibitor complex. we have reported the amino acid sequences of the domain with antitryptic activity and the homologous domain without activity. here we present the sequence of the domains as present in iti. the domain lacking antitryptic activity is the n-terminal part of the inhibitor hi-14, whereas ... | 1979 | 92449 |
| early detection of chlamydia trachomatis using fluorescent, dna binding dyes. | hela 229 cells were infected with genital tract strains of chlamydia trachomatis. after incubation for varying times the infected cells were fixed and stained with the fluorescent dna binding dyes hoechst 33258 or dapi for comparison with conventional giemsa stain. fluorochrome-treated preparations were examined by incident ultraviolet fluorescence microscopy and the giemsa-stained preparations by dark-ground light microscopy. chlamydial inclusion bodies could be identified unambiguously as earl ... | 1979 | 92480 |
| ia determinants on human t-cell subsets defined by monoclonal antibody. activation stimuli required for expression. | the nature of ia antigens which appear on human t cells after activation and the stimuli required for their expression was examined utilizing a monoclonal antibody reactive with the ia antigen framework. t cells were purified using monoclonal antibodies directed either at the entire t-cell population (okt3) or the t-cell inducer subset (okt4). by indirect immunofluorescence, it was shown that the human t-cell population contains no detectable ia+ cells in the resting state. in contrast, in exces ... | 1979 | 92523 |
| [microorganisms of genus haemophilus, their biological and serological characteristics (literature review)]. | 1979 | 92600 | |
| soluble proteins in the human atherosclerotic plaque. with spectral reference to immunoglobulins, c3-complement component, alpha 1-antitrypsin and alpha 2-macroglobulin. | a number of soluble proteins contained in human aortic intimal tissue was extracted into buffered saline (ph 7.4) and identified and quantitated by immunoelectrophoresis and immunodiffusion. the proteins included iga, igg, igm, b1c (c3), alpha 1-antitrypsin, alpha 2-macroglobulin, fibrinogen, albumin, ldl, hdl, alpha 1-acid glycoprotein, beta 2-glycoprotein, transferrin and ceruloplasmin. the concentration of soluble proteins was significantly higher in the atherosclerotic intima than in the nor ... | 1979 | 92993 |
| immunological properties of peptic fragments of bovine serum albumin. | the effect of peptic degradation on the immunological and antigenic properties of bovine serum albumin (bsa) was investigated. molecular fragments obtained after various times of digestion (3-360 min) were studied. enzymatic digestion resulted in a rapid loss of serologically defined antigenic determinants. the immunogenicity of the fragments as measured by the level of reaginic and total anti-bsa antibody response in bdf1 mice was also diminished. pre-treatment of mice with fragments exhibiting ... | 1979 | 93079 |
| delayed hypersensitivity to staphylococcus aureus in mice: in vivo responses to isolated staphylococcal antigens. | the development of delayed hypersensitivity (dh) to staphylococcus aureus in swiss mice was evaluated by the footpad (fp) assay. in order to determine which component of the bacteria was responsible for the in vivo immune reactivity, purified staphylococcal cell wall, cell membrane, protein a, lipoteichoic acid, teichoic acid, as well as lipid-free membrane proteins were isolated. the immune responses of mice receiving one to eight s. aureus injections indicated that the first dh peak, following ... | 1979 | 93087 |
| experimental infection with ancylostoma caninum larvae in mice. vi. serum protein pattern use due to repeated exposures to infection. | three mice groups were infected with various repeated doses and other four groups with single doses of ancylostoma caninum larvae. serum samples collected at various intervals were analysed electrophoretically. the results were compared first with an uninfected control group and then with those of the corresponding non-immunized single-dose-infected groups. remarkably decreased values of albumin, increased beta globulin and increased total globulins with a decreased a/g ratio were observed. ther ... | 1979 | 93128 |
| biosynthesis of human blood group t-, n- and m-specific immunodeterminants on human erythrocyte antigens. | we synthesized on tn erythrocytes with human sera, udp-gal, and activators t-specific haptenic structures in satisfactory yield. the specificity of this biosynthesis was ascertained by agglutination with human and animal anti-t, by specific absorption of human anti-t as well as by agglutination inhibition assays. with isolated human erythrocyte t antigen as substrate we synthesized n- and m-specific structures with sera from individual human donors in presence of cmp-sialic acid by incubation fo ... | 1979 | 93134 |
| the cerebellar corticonuclear and nucleocortical projections in the cat as studied with anterograde and retrograde transport of horseradish peroxidase. i. the paramedian lobule. | 1979 | 93421 | |
| dipyridamole affects myocardial adenosine kinase activity. | adenosine kinase (en 2.7.1.20) from rat and dog heart was purified until it was devoid of adenosine deaminase activity. a stimulation of adenosine kinase activity by dipyridamole was observed when the enzyme was assayed under optimal conditions. at low substrate concentrations adenosine kinase was inhibited by the drug. it increased the km for adenosine sevenfold. the effects of dipyridamole were mg2+-dependent. the adenosine-sparing action of dipyridamole at low substrate concentrations is in k ... | 1979 | 93442 |
| species differences in the chronotropic response to acid-base alterations. | the chronotropic response to acid-base alterations was studied in isolated spontaneously beating atria of rat, cat and rabbit. in the three species, atrial rate was found to be dependent on extracellular ph. both "respiratory" and "metabolic" alterations affected chronotropism to the same extent. decreasing ph from 7.8 led to a decrease in rate in the three species, although the rabbit kept atrial rate constant when ph changed between 7.65 and 7.18. there was a curvilinear relationship between r ... | 1979 | 93449 |
| [cis expression, at complementation, of mitochondrial mosaic gene exons regulating cytochrome b in saccharomyces cerevisiae (proceedings)]. | 1979 | 93454 | |
| a novel class of schizosaccharomyces pombe mutants, phenotypically unable to grow on glycerol, a respiratory substrate, but still able to oxidize glycerol aerobically [proceedings]. | 1979 | 93469 | |
| reverse transcriptase-associated rnase h. part iv. pyrophosphate does not inhibit rnase h activity of amv dna polymerase. | 1979 | 93479 | |
| alteration in the immunochemical dominance of determinants following the chemical modification of ox insulins: implications for the structure of the ox insulin monomer in solution. | insulins of differing species, together with chemically modified insulins, were used in cross-reactivity experiments employing selected antisera raised to ox insulin in the harley guinea-pig. the immunogen had been administered as a water-in-oil emulsion, using h. pertussis vaccine as adjuvant. antibody was generated by determinants in the c-terminus of the b chain plus the adjacent n-terminus of the a chain, in the central core of the a chain (a8-a14 region) and in its anti-parallel n-terminus ... | 1979 | 93526 |
| study of the role of serotonin in lithium action using shock-elicited fighting. | 1979 | 93531 | |
| vasoconstrictor effect of midodrine, st 1059, noradrenaline, etilefrine and dihydroergotamine on isolated human veins. | st 1059, the pharmacologically active metabolite of midodrine, is a powerful vasoconstrictor compound, acting by stimulation of alpha-receptors. it elicited 80% of noradrenaline-induced contraction of human veins. | 1979 | 93544 |
| generation of specfic t-cell suppressor function induced by streptococcus mutans in monkeys and mice. | specific suppressor cells in mice and monkeys can be induced with high doses of streptococcus mutans antigen. when these cells are further cultured with a low dose of s. mutans antigen in vitro, they secrete specific suppressor factors which decrease the cooperative responses to this antigen. in view of the sensitivity of these cells to anti-thy 1 and complement, and as they are not retained on nylon-wool, these suppressor cells are t cells. the suppressor factor exerts its effect on t helper ce ... | 1979 | 93576 |
| enhancement of feline leukemia virus-induced leukemogenesis in cats exposed to methylnitrosourea. | the effect of methylnitrosourea (mnu), a potent resorptive carcinogen, was evaluated for its influence on the susceptibility of adult cats to infection and induction of oncornavirus disease by feline leukemia virus (felv). young adult cats at an age previously demonstrated to be highly resistant to felv, were injected intravenously with moderately toxic doses (15-20 mg/kg) of mnu alone or with infections felv (rickard strain). following exposure to virus and chemical, cats were monitored for ant ... | 1979 | 93586 |
| alpha-fetoprotein inhibits antibody binding to acetylcholine receptor. significance for myasthenia gravis and other autoimmune diseases. | 1979 | 93589 | |
| practical considerations in using counterimmunoelectrophoresis to identify the principal causative agents of bacterial meningitis. | many clinical laboratories are currently using counterimmunoelectrophoresis (cie) as an aid in the rapid diagnosis of bacterial meningitis. because cross-reactions among causative agents have been reported, the present study was undertaken to explore the problems that might occur when reference and commercial antisera are used in cie. broth cultures of 35 bacterial strains were tested with 76 reference and commercial antisera by cie. some of the antisera tested failed to react with their homolog ... | 1979 | 93606 |
| comparison of auramine-rhodamine b and acridine orange for staining of acid-fast bacteria. | in cooperation of 6 laboratories in czechoslovakia and in the gdr, the efficiency of auramine-rhodamine b (ar) and acridine orange (ao) (short-time method) for staining of acid-fast bacilli was compared. whereas a former comparison of ar and ao (original method) pointed out the superiority of ar, the investigation of both methods used as short-time procedures showed significantly more acid-fast rods after using ao. the number of "false positive" results was somewhat higher on ar staining. howeve ... | 1979 | 93610 |
| characterization of adenovirus protein ix. | protein ix from adenovirus type 2 was purified by two methods, one from groups of nine hexons obtained by disrupting purified virus by heating in the presence of deoxycholate, and the other by a previously published method. the purified protein was used to obtain a monospecific antiserum. protein ix was found to possess both sub-group- and type-specific antigenic determinants which were apparently accessible within the groups of nine hexons. approximately 15 molecules of ix were found per group ... | 1979 | 93618 |
| the symptomatology with the most severe clinical course of spontaneous subarachnoid hemorrhage. | the symptomatology of 18 patients with the severest clinical course after subarachnoid hemorrhage (sah) is described and analyzed. seventeen patients died, five with an acute bulbar syndrome with cardiac arrest, and 12 with irreversible breakdown of brain function. one patient had an apallic syndrome with minimal signs of remission, who died 4 months after the first rebleeding. the cases are divided into five clinical groups on the basis of the acute brainstem symptomatology which set in instant ... | 1979 | 93630 |
| base-pairing between distant regions of the escherichia coli 16 s ribosomal rna in solution. | 1979 | 93645 | |
| problems associated with prolonged wear soft contact lenses. | complications of prolonged wearing of soft contact lenses are corneal infection, peripheral vascularization, giant papillary conjunctivitis and allergy, sterile ulcers, corneal warping, lens infection, protein and calcium deposits, lens fragility, and problems with disinfecting solutions. further long-term studies are needed to compare the safety of prolonged wear soft contact lenses with the safety of intraocular lenses, on which long-term studies are currently being done. | 1979 | 93736 |
| effects of intestinal amylase and trypsin on pancreatic secretion in the pig. | pigs were surgically prepared with external pancreatic fistulae and duodenal cannulae in order to elucidate whether the proposed intestinal feedback control of pancreatic secretion in the pig--as in rat and man--is exerted by trypsin. furthermore, the effect of intraluminal amylase on pancreatic secretion was studied. reintroduction of pancreatic juice into the duodenum or infusion of trypsin into the duodenum depressed the volume of the pancreatic flow and the protein output markedly. introduct ... | 1979 | 93774 |
| in vitro primary immunization of human peripheral blood lymphocytes to klh: evidence for hla-d-region restriction. | 1979 | 93813 | |
| recent advances in applied malaria immunology. | our present knowledge of cellular and humoral factors which are involved in immunity to plasmodial infections are discussed. immunization against plasmodial infection has been achieved in birds, rodents, simians, and humans. avian hosts have been immunized against gametocytes which resulted in inhibition of gametocytes within the mosquito vector. immunization of humans against plasmodial gametocytes would indirectly protect them against malaria by blocking mosquito transmission to other suscepti ... | 1979 | 93828 |
| triggering of autolytic cell wall degradation in escherichia coli by beta-lactam antibiotics. | a biochemical method was developed to quantitatively compare the effectiveness of beta-lactams in triggering murein degradation (autolysin activity) in escherichia coli. bacteria prelabeled in their cell walls with radioactive diaminopimelic acid in growth medium were exposed for 10 min to the antibiotics at the appropriate minimal growth inhibitory concentrations and at multiples of these values, and the rate of cell wall degradation was followed during subsequent penicillin-binding protein (pb ... | 1979 | 93877 |
| receptive field organization in areas 17 and 18 of the cat [proceedings]. | 1979 | 93893 | |
| inhibition kinetics of the plasma membrane atpase activity of the yeast schizosaccharomyces pombe [proceedings]. | 1979 | 93918 | |
| integration site of bovine leukemia virus dna in the bovine genome [proceedings]. | 1979 | 93923 | |
| closantel, a new antiparasitic hydrogen ionophore [proceedings]. | 1979 | 93944 | |
| semicarbazide-sensitive amine oxidase in rat aorta: a plasma-membrane enzyme [proceedings]. | 1979 | 93954 | |
| dna-directed cell-free protein-synthesizing system of bacillus subtilis. | a cell-free coupled system of transcription and translation using cell extracts from bacillus subtilis and dna from phage sp82 has been developed. under optimum conditions, it incorporated approx. 300 pmol methionine during a 1 h incubation. the activity of the system increased linearly as the concentration of s-150 supernatant fraction protein increased from 125 to 325 microgram per assay. the optimum mg2+ concentration was 12.5-15 mm. ribosomes required treatment with dnaase in order to reduce ... | 1979 | 93969 |
| identification of a silver binding protein associated with the cytological silver staining of actively transcribing nucleolar regions. | nucleoli isolated from novikoff hepatoma cells were stained with agno3 to demonstrate the typical staining of active ribosomal cistrons. pre-treatment of the nucleoli with 80 mm tris-hcl (ph 7.5) -- 2.0 m nacl did not interfere with silver staining. treatment of the nucleoli with 80 mm tris-hcl (ph 7.5) -- 0.15 m nacl did, however, eliminate silver binding. serial extraction of nucleoli with 2.0 m nacl buffer followed by 0.15 m nacl buffer also abolished silver staining. analysis of the supernat ... | 1979 | 93980 |
| bleomycin pharmacokinetics in man. ii. intracavitary administration. | 1979 | 93985 | |
| common enterobacterial antigen and onpg test in the taxonomy of the genus yersinia. | the detection of the common enterobacterial antigen (kunin) in strains of y. pestis, y. pseudotuberculosis and y. enterotocolitica has brought an additional reason for separating them from the pasteurella and for their inclusion in the family enterobacteriaceae. yersinia that give a positive onpg test lack true beta-galactoridase, except when they harbour a lactose plasmid. | 1979 | 94001 |
| hormone-responsive genes of the mouse mammary tumor virus. | by optimal hormonal treatment the production of exogenously transmitted mmtv can be stimulated in vitro to different degrees, depending on cultivation conditions and origin of tumor cells. moreover, after appropriate hormonal treatment, endogenous mmtv-y can be rescued from primary cell cultures derived from dimethyl benzanthracene- and hormone-induced c57bl/10 mouse mammary adenocarcinoma, as determined by reverse transcriptase assay, distribution of 3h-uridine-labelled viral particles, immunof ... | 1979 | 94006 |
| correlations between a peripheral-lymphocyte-specific surface antigen (lp) and the fc receptor on chicken spleen lymphocytes [proceedings]. | 1979 | 94015 | |
| demonstration of specific antigenecity of various fractions of human liver homogenate. | 1979 | 94039 | |
| effects of tamoxifen on the binding and metabolism of testosterone by human prostatic tissue and plasma in vitro. | the in-vitro metabolism of testosterone in benign and malignant prostatic tissue was examined and distinct quantitative differences between the two types of specimens were observed. the major metabolite of testosterone in the hyperplastic prostate was 5 alpha-dihydrotestosterone and a high 3 alpha(beta)-hydroxysteroid dehydrogenase activity was also detected. in the malignant tissue, 5 alpha-reductase activity was considerably reduced and there was little or no androstanediol formed; the 17 beta ... | 1979 | 94084 |
| structure of the rna portion of the rna-linked dna pieces in bacteriophage t4-infected escherichia coli cells. | 1979 | 94107 | |
| antigenic analysis of acute hemorrhagic conjunctivitis viruses (enterovirus type 70). | the antigenic characteristics of enterovirus type 70 (ev 70) were investigated by means of cross and kinetic neutralization tests (nt). twelve strains of ev 70 isolated in a period from 1971 to 1976 were analyzed using seven rabbit and one monkey hyper-immune sera. all the strains investigated were found to possess a common and prime variant antigens in varying proportions. accordingly, ev 70 isolates were devided intratypically into three antigenic sub groups; (1) prototype-like (four strain fr ... | 1979 | 94146 |
| [clinical and biochemical contributions on the effect of maprotiline and clomipramine in depressive states (preliminary observation)]. | this study has been conducted on 17 patients suffering from neurotic and psychotic depressions, who had not received a pharmacological antidepressive therapy since at least 1 month. 6 patients suffering from psychotic depression were treated with 100 mg clomipramine i.v. daily for 20 days; 11 patients, 7 of whom suffered from psychotic depression and 4 from neurotic depression, were treated with 150 mg maprotiline i.v. daily for 20 days. in both groups the therapy has been continued orally. in ... | 1979 | 94169 |
| antifetal and tumor-specific reactivity in human osteosarcoma. | 1979 | 94187 | |
| distribution and nature of desmosomes in the bovine developing ruminal epithelium. | desmosomes entirely similar to those of the deeper layers of ruminal epithelium are seen in the luminal layers of the early fetal ruminal epithelium. in the older fetuses, these desmosomes have morphological features that reveal to some extent the occurrence of processes of keratinization. this could indicate that the basis for cell keratinization is already present in the fetus and that postnatal keratinization corresponds mainly to the full development of the prenatally existing pattern of dif ... | 1979 | 94228 |
| cross-reactions between haemophilus influenzae and nineteen other bacterial species. | forty-one different antigens were demonstrated in an antigen preparation obtained by sonication of a haemophilus influenzae (h. influenzae) type b strain, using crossed immunoelectrophoresis and antiserum obtained from rabbits. antigens were characterized by absorption experiments with whole heat-killed bacteria, temperature resistance and protein and polysaccharide staining. cross-reactions between h. influenzae type b and 19 other bacterial species were studied by various quantitative immunoel ... | 1979 | 94235 |
| subpopulations of human peripheral blood cells: analysis of granulocytic progenitor cells by flow cytometry and immunologic surface markers. | normal human peripheral blood cells were separated into different populations based upon isopycnic sedimentation, e rosetting, and eac rosetting. each population was characterized according to morphology, surface markers, granulocytic colony formation in semi-solid media, and stainable rna content by acridine orange (ao) flow cytometry. these techniques enrich for a population of cells that is characterized by a lymphoid morphology, a high granulocytic-macrophage progenitor cell cloning efficien ... | 1979 | 94243 |
| mycoplasma pneumonia presenting as meningoencephalitis and hemolytic anemia. | simultaneous occurrence of cold agglutinin hemolytic anemia and central nervous system disease due to mycoplasma pneumonia is extremely rare. a patient is described who initially presented with severe hemolysis and diffuse neurologic dysfunction which appeared during the period of roentgenographic resolution of her pneumonia. spectrum, pathogenesis, and antimicrobial treatment of the neurologic complications are reviewed. | 1979 | 94244 |
| [vascularization of malignant melanoma in golden hamster]. | 1979 | 94247 | |
| rapid detection of malaria and other bloodstream parasites by fluorescence microscopy with 4'6 diamidino-2-phenylindole (dapi). | dapi is a fluorescent dye which appears to complex specifically with dna. we have used this probe to detect and identify malarial infections by fluorescence microscopy. experiments were conducted using plasmodium berghei yoeli--infected mouse blood, p. lophurae--infected duck blood, and p. vivax--infected human blood. infected avian blood was used to detect parasites within nucleated erythrocytes. control blood smears from uninfected hosts revealed fluorescence only in the leukocytes of mammalia ... | 1979 | 90141 |
| structure of products of the moloney murine leukemia virus endogenous dna polymerase reaction. | we have investigated the process by which the single-stranded rna genome of moloney murine leukemia virus is copied into dna in vitro. dna synthesis if initiated near the 5' end of the genome, and the elongation of the growing chain occurs by a jumping mechanism whereby the dna synthesized at the 5' end of the genome is elongated along the 3' end. unique dna fragments synthesized beyond the 5' end of the genome in vitro have, at their 5' and 3' ends, copies of unique sequences from the 5' and 3' ... | 1979 | 90161 |
| [improving the effectiveness of virological studies in influenza]. | 1979 | 90208 | |
| steroid treatment of male subfertility caused by antisperm antibodies. | 47 subfertile men with significant titres of antisperm antibodies were treated with one of two steroid regimens. the results were assessed by changes in sperm-counts and in serum antibody titres and by subsequent pregnancies. 15 oligozoospermic men were treated with prednisone 5 mg three times a day for 3--12 months. sperm-counts became normal in 10 men and 4 of their wives became pregnant. 14 men with normal sperm-counts received the same treatment: antibody titres fell slightly and 3 of their ... | 1979 | 90218 |
| are there antigenic variants of hepatitis a virus? | 1979 | 90289 | |
| ethanol inhibition of antigen-induced histamine release from guinea pig lung: correlation with intracellular levels of cyclic nucleotides. | 1979 | 90324 | |
| [species and interspecies antigenic specificity of house dust mites (genus dermatophagoides)]. | 1979 | 90327 | |
| sister-chromatid exchanges in human lymphocytes exposed during go to four classes of dna-damaging chemicals. | human lymphocytes were treated prior to mitogenic stimulation with varying concentrations of 6 cytostatic drugs representing 4 classes of dna-damaging chemicals. afterwards the cells were washed to remove residual chemical and cultured in the presence of bromodeoxyuridine for analysis of sister-chromatid exchanges (sces). a dose-related increase in sces was observed in cells exposed during go to the alkylating chemicals mitomycin c, chlorambucil, and thiotepa, while significant increases in sces ... | 1979 | 90341 |
| a normal cell protein cross-reactive to the major abelson murine leukaemia virus gene product. | 1979 | 90344 | |
| use of delmadinone acetate. | 1979 | 90422 |