Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| assessment of the risk of african swine fever introduction into finland using nora-a rapid tool for semiquantitative assessment of the risk. | the nora rapid risk assessment tool was developed for situations where there is a change in the disease status of easily transmissible animal diseases in neighbouring countries or in countries with significant interactions with finland. the goal was to develop a tool that is quick to use and will provide consistent results to support risk management decisions. the model contains 63 questions that define the potential for entry and exposure by nine different pathways. the magnitude of the consequ ... | 2017 | 28303673 |
| insights into early pig domestication provided by ancient dna analysis. | pigs (sus scrofa) were first domesticated between 8,500 and 8,000 cal bc in the near east, from where they were subsequently brought into europe by agriculturalists. soon after the arrival of the first domestic pigs in northern europe (~4500 bc), farmers are thought to have started to incorporate local wild boars into their swine herds. this husbandry strategy ultimately resulted in the domestication of european wild boars. here, we set out to provide a more precise geographic and temporal frame ... | 2017 | 28300151 |
| peri-conceptional under-nutrition alters the expression of trim28 and zfp57 in the endometrium and embryos during peri-implantation period in domestic pigs. | dna methylation is maintained by the main elements of methylation complex-tripartite motif containing 28 (trim28) and zinc finger protein 57 (zfp57). previously, it was found that the activity of trim28 and zfp57 determines the process of dna methylation and preserves over-expression of genes. we hypothesized that restricted diet applied during peri-conceptional period may induce changes in the expression of methylation complex in porcine endometrium and embryos during the peri-implantation peri ... | 2017 | 28295703 |
| effects of different iron supply to pregnant sows (sus scrofa domestica l.) on reproductive performance as well as iron status of new-born piglets. | the present study aimed to investigate the effects of different iron (fe) supply to sows during gestation on their reproductive performance and placental fe load. additionally, the fe status of the corresponding offspring was assessed. twenty multiparous sows were fed from insemination to farrowing with isoenergetic and isonitrogenic balanced diets differing in fe content. the diet low in fe (group -fe) was mainly composed of soybean meal and maize meal and had a fe content of 114 mg/kg dm. for ... | 2017 | 28293962 |
| phosphorylated pullulan coating enhances titanium implant osseointegration in a pig model. | to investigate the effect of coating a titanium implant surface with a phosphorylated exopolysaccharide, pullulan, on the peri-implant bone formation and implant osseointegration. | 2017 | 28291848 |
| cardioprotective effect of nicorandil against myocardial injury following cardiac arrest in swine. | nicorandil, a vasodilatory drug used to treat angina, was reported to protect against myocardial ischemia-reperfusion injury in various animal models. however, its cardioprotective action following cardiac arrest is unknown. we examined the cardioprotective effects of nicorandil in a porcine model of cardiac arrest and resuscitation. | 2017 | 28285861 |
| how much does it cost to look like a pig in a wild boar group? | hybridization between domestic and wild species is known to widely occur and it is reported to be one of the major causes of the current biodiversity crisis. despite this, poor attention has been deserved to the behavioural ecology of hybrids, in particular in relation to their social behaviour. we carried out a camera trap study to assess whether phenotypically anomalous colouration in wild boar, i.e. potentially introgressed with domestic pigs, affected the hierarchical structure of wild boar ... | 2017 | 28274764 |
| sequential activation of different pathway networks in ischemia-affected and non-affected myocardium, inducing intrinsic remote conditioning to prevent left ventricular remodeling. | we have analyzed the pathway networks of ischemia-affected and remote myocardial areas after repetitive ischemia/reperfusion (r-i/r) injury without ensuing myocardial infarction (mi) to elaborate a spatial- and chronologic model of cardioprotective gene networks to prevent left ventricular (lv) adverse remodeling. domestic pigs underwent three cycles of 10/10 min r-i/r by percutaneous intracoronary balloon inflation/deflation in the mid left anterior descending artery, without consecutive mi. sh ... | 2017 | 28266659 |
| the 'real welfare' scheme: benchmarking welfare outcomes for commercially farmed pigs. | animal welfare standards have been incorporated in eu legislation and in farm assurance schemes, based on scientific information and aiming to safeguard the welfare of the species concerned. recently, emphasis has shifted from resource-based measures of welfare to animal-based measures, which are considered to assess more accurately the welfare status. the data used in this analysis were collected from april 2013 to may 2016 through the 'real welfare' scheme in order to assess on-farm pig welfar ... | 2017 | 28249629 |
| continuous intraoperative neuromonitoring study using pigs for the prevention of mechanical recurrent laryngeal nerve injury in esophageal surgery. | during esophageal surgery, clamping injury and injury associated with the use of energy devices are common mechanisms underlying intraoperative recurrent laryngeal nerve (rln) damage. recently, intraoperative neuromonitoring (ionm) has been applied to prevent rln injury. this study was aimed at investigating the changes in the emg signals associated with clamping injury of the rln caused by picking up of the nerve with tweezers in domestic pigs. | 2017 | 28142325 |
| osteochondrosis, synovial fossae, and articular indentations in the talus and distal tibia of growing domestic pigs and wild boars. | articular osteochondrosis (oc) often develops in typical locations within joints, and the characterization of oc distribution in the pig tarsus is incomplete. prevalence of oc is high in domestic pigs but is presumed to be low in wild boars. postmortem and computed tomography (ct) examinations of the talus and distal tibia from 40 domestic pigs and 39 wild boars were evaluated for the locations and frequencies of oc, synovial fossae, and other articular indentations, and frequency distribution m ... | 2017 | 28129094 |
| the complete mitochondrial genome sequence of the indigenous i pig (sus scrofa) in vietnam. | the i pig is a long nurtured longstanding breed in vietnam, and contains excellent indigenous genetic resources. however, after 1970s, i pig breeds have become a small population because of decreasing farming areas and increasing pressure from foreign breeds with a high growth rate. thus, there is now the risk of the disappearance of the i pigs breed. the aim of this study was to focus on classifying and identifying the i pig genetic origin and supplying molecular makers for conservation activit ... | 2017 | 28111450 |
| radiosynthesis and evaluation of [11c]3-hydroxycyclopent-1-enecarboxylic acid as potential pet ligand for the high-affinity γ-hydroxybutyric acid binding sites. | γ-hydroxybutyric acid (ghb) is an endogenous neuroactive substance and proposed neurotransmitter with affinity for both low- and high-affinity binding sites. a radioligand with high and specific affinity toward the high-affinity ghb binding site would be a unique tool toward a more complete understanding of this population of binding sites. with its high specific affinity and monocarboxylate transporter (mct1) mediated transport across the blood-brain barrier in pharmacological doses, 3-hydroxyc ... | 2017 | 28095676 |
| generation of germline ablated male pigs by crispr/cas9 editing of the nanos2 gene. | genome editing tools have revolutionized the generation of genetically modified animals including livestock. in particular, the domestic pig is a proven model of human physiology and an agriculturally important species. in this study, we utilized the crispr/cas9 system to edit the nanos2 gene in pig embryos to generate offspring with mono-allelic and bi-allelic mutations. we found that nanos2 knockout pigs phenocopy knockout mice with male specific germline ablation but other aspects of testicul ... | 2017 | 28071690 |
| accuracy of echocardiographic area-length method in chronic myocardial infarction: comparison with cardiac ct in pigs. | we evaluated echocardiographic area-length methods to measure left ventricle (lv) volumes and ejection fraction (ef) in parasternal short axis views in comparison with cardiac computed tomography (ct) in pigs with chronic myocardial infarction (mi). | 2017 | 28069008 |
| electrical impedance tomography for non-invasive assessment of stroke volume variation in health and experimental lung injury. | functional imaging by thoracic electrical impedance tomography (eit) is a non-invasive approach to continuously assess central stroke volume variation (svv) for guiding fluid therapy. the early available data were from healthy lungs without injury-related changes in thoracic impedance as a potentially influencing factor. the aim of this study was to evaluate svv measured by eit (svveit) against svv from pulse contour analysis (svvpc) in an experimental animal model of acute lung injury at differ ... | 2017 | 28039243 |
| normal values for heart electrophysiology parameters of healthy swine determined on electrophysiology study. | swine are a well-recognized animal model for human cardiovascular diseases. despite the widespread use of porcine model in experimental electrophysiology, still no reference values for intracardiac electrical activity and conduction parameters determined during an invasive electrophysiology study (eps) have been developed in this species thus far. | 2017 | 28028980 |
| impact of synthetic elements on aortic root haemodynamics: computed fluid dynamics of aortic root reconstruction and valve reimplantation. | the aim was to evaluate the impact of the aortic valve reimplantation (david) and of the aortic root (aor) remodelling (yacoub) on the aor haemodynamics. | 2017 | 28013289 |
| anemia tolerance during normo-, hypo-, and hypervolemia. | restrictive intraoperative fluid management has been demonstrated to improve outcome of visceral and lung surgery in several studies. however, subsequent hypovolemia (hov) may be accompanied by a decrease of anemia tolerance, resulting in increased transfusion needs. we therefore investigated the effect of volume status on anemia tolerance. | 2017 | 27990642 |
| dynamics of myosin heavy chain isoform transition in the longissimus muscle of domestic and wild pigs during growth: a comparative study. | dynamics of myofiber differentiation/maturation in porcine skeletal muscle is associated with domestication, breeding and rearing conditions. this study was aimed to comparatively elucidate the age-dependent myosin heavy chain (myhc) isoform expression and transition pattern in domestic and wild pig (wp) skeletal muscle from birth until adulthood. domestic pigs (dps) of large white breed raised in conventional production system were compared with wps reared in a large hunting enclosure. muscle s ... | 2017 | 27345286 |
| effects of carbon dioxide insufflation during direct cholangioscopy on biliary pressures and vital parameters: a pilot study in porcine models. | direct per-oral cholangioscopy allows endoscopic visualization of the biliary tract. insufflation with carbon dioxide (co2) is an alternative to saline solution irrigation during direct cholangioscopy. there are no data on maximal co2insufflation in direct cholangioscopy without causing biliary barotrauma or fatal gas embolism. we aimed to evaluate the safety of increasing co2insufflation in direct cholangioscopy without causing biliary barotrauma or fatal gas embolism. | 2017 | 27327853 |
| histopathological comparative analysis of periimplant bone inflammatory response after dental implant insertion using flap and flapless surgical technique. an experimental study in pigs. | to evaluate by histopathological analysis the peri-implant bone inflammation degree, in certain time intervals (7, 14, 21 and 28 days), following mini-incision flapless and flap implant placement. | 2017 | 27393033 |
| influence of on-farm pig salmonella status on salmonella shedding at slaughter. | the risk of salmonella shedding among pigs at slaughter with regard to their previous on-farm salmonella status was assessed in a group of pigs from a farm from ne of spain. a total of 202 pigs that had been serologically monitored monthly during the fattening period and from which mesenteric lymph nodes (mln) and faecal (sfec) samples were collected at slaughter for salmonella isolation were included. a repeated-measures anova was used to assess the relationship between mean od% values during t ... | 2017 | 27549508 |
| periconceptional undernutrition affects in utero methyltransferase expression and steroid hormone concentrations in uterine flushings and blood plasma during the peri-implantation period in domestic pigs. | female undernutrition during early pregnancy may affect the physiological pattern of genomic dna methylation. we hypothesised that in utero dna methylation may be impaired in females fed a restrictive diet in early pregnancy. in this study we evaluated whether poor maternal nutritional status, induced by applying a restricted diet during the peri-conceptional period, may influence: (1) the potential for in utero dna methylation, expressed as changes in the mrna expression and protein abundance o ... | 2017 | 27534526 |
| a cartographic tool for managing african swine fever in eurasia: mapping wild boar distribution based on the quality of available habitats. | the current african swine fever (asf) epidemic in eurasia represents a risk for the swine industry with devastating socio-economic and political consequences. wild boar appears to be a key factor in maintaining the disease in endemic areas (mainly the russian federation) and spreading the disease across borders, including within the european union. to help predict and interpret the dynamics of asf infection, we developed a standardized distribution map based on global land cover vegetation (glob ... | 2017 | 27596983 |
| a simulation model to determine sensitivity and timeliness of surveillance strategies. | animal surveillance systems need regular evaluation. we developed an easily applicable simulation model of the german wild boar population to investigate two evaluation attributes: the sensitivity and timeliness (i.e. the ability to detect a disease outbreak rapidly) of a surveillance system. classical swine fever (csf) was used as an example for the model. csf is an infectious disease that may lead to massive economic losses. it can affect wild boar as well as domestic pigs, and csf outbreaks i ... | 2017 | 27619421 |
| cholinergic profiles in the goettingen miniature pig (sus scrofa domesticus) brain. | central cholinergic structures within the brain of the even-toed hoofed goettingen miniature domestic pig (sus scrofa domesticus) were evaluated by immunohistochemical visualization of choline acetyltransferase (chat) and the low-affinity neurotrophin receptor, p75ntr. chat-immunoreactive (-ir) perikarya were seen in the olfactory tubercle, striatum, medial septal nucleus, vertical and horizontal limbs of the diagonal band of broca, and the nucleus basalis of meynert, medial habenular nucleus, z ... | 2017 | 27490949 |
| biodegradable polymeric stents for vascular application in a porcine carotid artery model: english version. | over the past years the development of biodegradable polymeric stents has made great progress; nevertheless, essential problems must still be solved. modifications in design and chemical composition should optimize the quality of biodegradable stents and remove the weaknesses. new biodegradable poly-l-lactide/poly-4-hydroxybutyrate (plla/p4hb) stents and permanent 316l stents were implantedendovascularly into both common carotid arteries of 10 domestic pigs. at 4 weeks following implantation, co ... | 2017 | 27034581 |
| still room for improvement: preclinical and bench testing of a thin-strut cobalt-chromium bare-metal stent with passive coating. | there is a renewed interest in bare-metal stent (bms) design as degradable polymer coatings are increasingly used as drug-delivery vehicles in drug-eluting stents (dess), leaving it to the bms platform to determine the long-term outcome of des treatment. in this study comprising preclinical and bench tests, we compare two modern thin-strut bmss of different design. angiography, morphometry, and histopathology data were acquired in a porcine coronary artery model in a 28-day single-stent study (1 ... | 2017 | 27149341 |
| a simple porcine model of inducible sustained atrial fibrillation. | the surgical management of atrial fibrillation (af) is an evolving field with a history of testing various lesion sets and ablation technologies. previous animal models of af require a chronic intervention to make af reliably inducible. our objective was to create an acute, reliable, and reproducible porcine model of sustained af. to accomplish this, 21 adult domestic pigs underwent median sternotomy. methods to induce af were then performed sequentially: manual stimulation, rapid pacing (200 be ... | 2017 | 26889882 |
| performance of a novel bipolar/monopolar radiofrequency ablation device on the beating heart in an acute porcine model. | although the advent of ablation technology has simplified and shortened surgery for atrial fibrillation, only bipolar clamps have reliably been able to create transmural lesions on the beating heart. currently, there are no devices capable of reproducibly creating the long linear lesions in the right and left atria needed to perform a cox-maze procedure. this study evaluated the performance of a novel suction-assisted radiofrequency device that uses both bipolar and monopolar energy to create le ... | 2017 | 24145972 |
| the effect of high-fat diet on the composition of the gut microbiota in cloned and non-cloned pigs of lean and obese phenotype. | the aim of this study was to investigate the effect of high-far-high-energy diet on cloned and non-cloned domestic pigs of both lean and obese phenotype and to evaluate if the lean cloned pigs had a lower inter-individual variation as compared with non-cloned pigs. the microbiota of colon and terminal ileum was investigated in cloned and non-cloned pigs that received a high-far-high-energy diet with either restricted or ad libitum access to feed, resulting in lean and obese phenotypes, respectiv ... | 2017 | 23974297 |
| 1ppab5. acoustic radiation force to reposition kidney stones. | our group has introduced transcutaneous ultrasound to move kidney stones in order to expel small stones or relocate an obstructing stone to a nonobstructing location. human stones and metalized beads (2-8 mm) were implanted ureteroscopically in kidneys of eight domestic swine. ultrasonic propulsion was performed using a diagnostic imaging transducer and a verasonics ultrasound platform. stone propulsion was visualized using fluoroscopy, ultrasound, and the ureteroscope. successful stone movement ... | 2017 | 26207161 |
| assessing immune competence in pigs by immunization with tetanus toxoid. | immune competence can be tested by challenging organisms with a set of infectious agents. however, disease control requirements impose restrictions on the infliction of infections upon domestic pigs. alternatively, vaccinations induce detectable immune responses that reflect immune competence. here, we tested this approach with tetanus toxoid (tt) in young domestic pigs. to optimize the vaccination protocol, we immunized the pigs with a commercial tt vaccine at the age of 21 or 35 days. booster ... | 2018 | 28554336 |
| the in vivo performance of a novel thermal accelerant agent used for augmentation of microwave energy delivery within biologic tissues during image-guided thermal ablation: a porcine study. | to investigate the effects of a novel caesium-based thermal accelerant (ta) agent on ablation zone volumes following in vivo microwave ablation of porcine liver and skeletal muscle, and to correlate the effects of ta with target organ perfusion. | 2018 | 28540805 |
| impact of direct epispinal stimulation on bladder and bowel functions in pigs: a feasibility study. | this study assesses the potential of epispinal (subdural) stimulation application in the treatment of urinary and bowel neurological disorders. acute experiments were performed on a large animal model - the domestic pig - to develop a new methodology facilitating future results and technology transfers to human. | 2018 | 28605134 |
| peri-conceptional under-nutrition alters transcriptomic profile in the endometrium during the peri-implantation period-the study in domestic pigs. | female under-nutrition during early pregnancy may affect the physiological pattern of the transcriptomic profile in the endometrium. we aimed to determine if restricted diet applied to females during peri-conceptional period, that is, from the onset of the oestrus until day nine of pregnancy, alters transcriptomic profile in the endometrium during the peri-implantation period. the restricted diet gilts were fed forage, in which the dose of proteins and energy had been reduced by 30% compared to ... | 2018 | 28944507 |
| randomized controlled trial comparing submucosal endoscopy with mucosal resection and endoscopic submucosal dissection in the esophagus and stomach: animal study. | in western countries, endoscopic submucosal dissection (esd) has not prevailed as a result of training problems and a target patient population. we have previously reported a hybrid esd technique, submucosal endoscopy with mucosal resection (semr), in which the submucosal dissection is carried out chiefly by blunt balloon dissection. we have also reported successful application in the porcine colon. in the present study, we compared the safety and efficacy of semr with esd in the porcine esophag ... | 2018 | 28664661 |
| production, performance, slaughter characteristics, and meat quality of ziwuling wild crossbred pigs. | wild boars, because of their large size and ability to survive adverse conditions, are usually used to cross with domestic breeds to improve the quality of domesticated pigs. this study aimed to investigate the growth performance, slaughter performance, and meat quality of ziwuling crossbred pigs. crossbred pigs in four groups (n = 8 per group, 4 boars and 4 sows, all aged 100 days), f1[wild × b (bamei)], f1 × b, f1 × y (yorkshire), and f1 × f1, were selected at a commercial pig farm. growth per ... | 2018 | 29064063 |
| preclinical animal models for temporomandibular joint tissue engineering. | there is a paucity of in vivo studies that investigate the safety and efficacy of temporomandibular joint (tmj) tissue regeneration approaches, in part due to the lack of established animal models. review of disease models for study of tmj is presented herein with an attempt to identify relevant preclinical animal models for tmj tissue engineering, with emphasis on the disc and condyle. although degenerative joint disease models have been mainly performed on mice, rats, and rabbits, preclinical ... | 2018 | 29121815 |
| metabolic syndrome alters expression of insulin signaling-related genes in swine mesenchymal stem cells. | metabolic syndrome (mets) is associated with insulin resistance (ir) and impaired glucose metabolism in muscle, fat, and other cells, and may induce inflammation and vascular remodeling. endogenous reparative systems, including adipose tissue-derived mesenchymal stem/stromal cells (msc), are responsible for repair of damaged tissue. msc have also been proposed as an exogenous therapeutic intervention in patients with cardiovascular and chronic kidney disease (ckd). the feasibility of using autol ... | 2018 | 29101070 |
| characterization of domestic pig spermatogenesis using spermatogonial stem cell markers in the early months of life. | in pigs, spermatogonial stem cells (sscs), which include gonocytes and undifferentiated spermatogonia, are classically defined as being present till up to 2 months of life. however, knowledge about this transition from gonocytes to undifferentiated spermatogonia in pigs is limited. in this study, we characterized pig sscs in neonatal (n = 6), one-month-old (1-mo-old, n = 6), two-month-old (2-mo-old, n = 6), and adult testes (n = 6) anatomically, histologically, and immunohistologically. anatomic ... | 2018 | 29156418 |
| evaluation of protection induced by immunisation of domestic pigs with deletion mutant african swine fever virus beninδmgf by different doses and routes. | a live attenuated african swine fever virus (asfv) vaccine candidate, produced by deletion of several genes belonging to multi-gene families mgf360 and 505 from virulent benin 97/1 strain (beninδmgf), induces protection in pigs against parental virulent strain. in order to better define the safety and efficacy of this attenuated vaccine candidate and to understand protective mechanisms, we extended previous studies by intramuscular immunisation of pigs with the deletion mutant beninδmfg at diffe ... | 2018 | 29254837 |
| host contributes to longitudinal diversity of fecal microbiota in swine selected for lean growth. | in pigs, gut bacteria have been shown to play important roles in nutritional, physiological, and immunological processes in the host. however, the contribution of their metagenomes or part of them, which are normally reflected by fragments of 16s rrna-encoding genes, has yet to be fully investigated. | 2018 | 29301569 |
| intraoperative cardiovascular response of natural orifice transluminal endoscopic surgery versus laparoscopy: a comparative animal study. | natural orifice transluminal endoscopic surgery (notes) emerged as a new alternative method in minimally invasive techniques. although a very small number of studies have compared the physiologic response in notes to laparoscopy, the results remain controversial. | 2018 | 29319013 |
| genetic and immunogenicity analysis of porcine circovirus type 2 strains isolated in central china. | porcine circovirus type 2 (pcv2) is an economically important pathogen in domestic pigs and wild boars all around the world. to understand the molecular epidemiology of pcv2 strains circulating in central china and to provide a potential vaccine candidate strain, we analyzed the genetic variations of 46 pcv2 isolates circulating from 2009 to 2016 in henan province (24 detected in the field from 2009-2013 and 22 from 2013-2016) and evaluated the efficacy of an isolate as a vaccine candidate strai ... | 2018 | 29305646 |
| immunisation of pigs by dna prime and recombinant vaccinia virus boost to identify and rank african swine fever virus immunogenic and protective proteins. | african swine fever virus (asfv) causes an acute haemorrhagic fever in domestic pigs with high socio-economic impact. no vaccine is available limiting options for control. although live attenuated asfv can induce up to one hundred percent protection against lethal challenge, little is known of the antigens which induce this protective response. to identify additional asfv immunogenic and potentially protective antigens we cloned 47 viral genes in individual plasmids for gene vaccination and in r ... | 2018 | 29386289 |
| a serologic survey of pathogens in wild boar ( sus scrofa) in sweden. | the wild boar ( sus scrofa) population has increased markedly during the last three decades in sweden and in other parts of europe. this population growth may lead to increased contact between the wild boar and the domestic pig ( sus scrofa scrofa), increasing the risk of transmission of pathogens. the objective of our study was to estimate the seroprevalence of selective pathogens, known to be shared between wild boars and domestic pigs in europe, in three wild boar populations in sweden. in to ... | 2018 | 29377751 |
| viability and biocompatibility of an adhesive system for intrarenal embedding and endoscopic removal of small residual fragments in minimally-invasive stone treatment in an in vivo pig model. | to evaluate the viability and biocompatibility of a novel, patented bioadhesive system for intrarenal embedding and retrieval of residual fragments after endoscopic lithotripsy. complete stone clearance via active removal of residual fragments (rf) after intracorporeal laser lithotripsy may be time-consuming and fail in many cases. therefore, the novel adhesive has been developed and evaluated for the first time in an in vivo pig model in the present work. | 2018 | 29368229 |
| genetic diversity, breed composition and admixture of kenyan domestic pigs. | the genetic diversity of african pigs, whether domestic or wild has not been widely studied and there is very limited published information available. available data suggests that african domestic pigs originate from different domestication centers as opposed to international commercial breeds. we evaluated two domestic pig populations in western kenya, in order to characterize the genetic diversity, breed composition and admixture of the pigs in an area known to be endemic for african swine fev ... | 2018 | 29357367 |
| intrarenal fat deposition does not interfere with the measurement of single-kidney perfusion in obese swine using multi-detector computed tomography. | altered vascular structure or function in several diseases may impair renal perfusion. multi-detector computed tomography (mdct) is a non-invasive tool to assess single-kidney perfusion and function based on dynamic changes in tissue attenuation during contrast media transit. however, changes in basal tissue attenuation might hamper these assessments, despite background subtraction. evaluation of iodine concentration using the dual-energy (dect) mdct mode allows excluding effects of basal values ... | 2018 | 29339048 |
| the retina of the collared peccary (pecari tajacu): structure and function. | to study retinal morphology and function in the collared peccary, an ungulate species distantly related to the domestic pig. | 2018 | 29336116 |
| cardiovascular function of modern pigs does not comply with allometric scaling laws. | growing concerns have been expressed regarding cardiovascular performance in modern farm pigs, which has been proposed as a critical factor contributing to the reduced adaptability of modern pigs to stress. here we tested the hypothesis that cardiac dimensions and pump function in modern heavy farm pigs are disproportionally low for their body weight, and investigated potential underlying mechanisms. the results from the present study indeed demonstrate disproportionally low values for stroke vo ... | 2018 | 29335617 |
| faecal escherichia coli as biological indicator of spatial interaction between domestic pigs and wild boar (sus scrofa) in corsica. | on the mediterranean island of corsica, cohabitation between sympatric domestic pigs and eurasian wild boar (sus scrofa) is common and widespread and can facilitate the maintenance and dissemination of several pathogens detrimental for the pig industry or human health. in this study, we monitored a population of free-ranging domestic pigs reared in extensive conditions within a 800-ha property located in central corsica which was frequently visited by a sympatric population of wild boar between ... | 2018 | 29322645 |
| assessing the utility of metabarcoding for diet analyses of the omnivorous wild pig (sus scrofa). | wild pigs (sus scrofa) are an invasive species descended from both domestic swine and eurasian wild boar that was introduced to north america during the early 1500s. wild pigs have since become the most abundant free-ranging exotic ungulate in the united states. large and ever-increasing populations of wild pigs negatively impact agriculture, sport hunting, and native ecosystems with costs estimated to exceed $1.5 billion/year within the united states. wild pigs are recognized as generalist feed ... | 2018 | 29321862 |
| hepatitis e virus infection of slaughtered healthy pigs in brazil. | hepatitis e virus (hev) is an emerging pathogen that can be transmitted through contaminated raw or undercooked meat derived from domestic pigs. hev infections have been documented among pig herds, pig products and environmental samples raising concern about the spread of the virus. hev genotypes 3 and 4 are considered zoonotic and have been linked to human cases. hev was detected in 51 of 335 bile samples (15.2%) from healthy pigs in minas gerais, brazil. phylogenetic analysis of partial sequen ... | 2018 | 29441690 |
| the zbed6-igf2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals. | a single nucleotide substitution in the third intron of insulin-like growth factor 2 (igf2) is associated with increased muscle mass and reduced subcutaneous fat in domestic pigs. this mutation disrupts the binding of the zbed6 transcription factor and leads to a threefold up-regulation ofigf2expression in pig skeletal muscle. here, we investigated the biological significance of zbed6-igf2interaction in the growth of placental mammals using two mouse models, zbed6 knock-out (zbed6-/-) andigf2kno ... | 2018 | 29440408 |
| accurate depth of radiofrequency-induced lesions in renal sympathetic denervation based on a fine histological sectioning approach in a porcine model. | ablation lesion depth caused by radiofrequency-based renal denervation (rdn) was limited to <4 mm in previous animal studies, suggesting that radiofrequency-rdn cannot ablate a substantial percentage of renal sympathetic nerves. we aimed to define the true lesion depth achieved with radiofrequency-rdn using a fine sectioning method and to investigate biophysical parameters that could predict lesion depth. | 2018 | 29440276 |
| the effect of three different surgical techniques for colon anastomosis on regional postoperative microperfusion: laser doppler flowmetry study in pigs. | the optimal surgical approach to reconnecting bowel ends safely after resection is of great importance. | 2018 | 29439318 |
| genomic sequence of a swine pasivirus type 1 strain identified in u.s. swine. | we report for the first time in the united states the identification of a swine pasivirus (spav) strain with a genomic sequence identity of less than 80% to other spavs reported in europe and china, using a next-generation sequencing (ngs) technique in sow tissues collected from an animal study conducted in 2001, suggesting virus circulation in domestic swine. | 2018 | 29439048 |
| identification of two novel foot-and-mouth disease virus cytotoxic t lymphocyte epitopes that can bind six sla-i proteins. | currently available vaccines from inactivated foot-and-mouth disease virus (fmdv) only protect animals by inducing neutralizing antibodies. a vaccine that contains cytotoxic t lymphocytes (ctl) epitopes to induce strong ctl responses might protect animals more effectively. herein, we used swine leukocyte antigen class i (slai) proteins derived from six different strains of domestic pigs to screen and identify shared fmdv ctl epitopes. four potential fmdv ctl epitopes (q01, q02, as3, and qa4) wer ... | 2018 | 29432828 |
| aujeszky's disease and hepatitis e viruses transmission between domestic pigs and wild boars in corsica: evaluating the importance of wild/domestic interactions and the efficacy of management measures. | wildlife species as reservoirs of infectious pathogens represent a serious constraint in the implementation of disease management strategies. in the mediterranean island of corsica, the dynamics of hepatitis e virus (hev) and aujeszky's disease virus (adv) are suspected to be influenced by interactions between wild and domestic pigs. to improve our understanding of these influences, we first compared the seroprevalences of both viruses in domestic pig populations from different locations with co ... | 2018 | 29417054 |
| voluntary locomotor activity promotes myogenic growth potential in domestic pigs. | self-determined physical activity is an essential behavioural need and can vary considerably between individuals of a given species. although locomotion is suggested as a prerequisite for adequate function of skeletal muscle, domestic pigs are usually reared under limited space allowance. the aim of our study was to investigate if a different voluntary locomotor activity leads to altered properties in the muscle structure, biochemistry and mrna expression of selected genes involved in myogenesis ... | 2018 | 29416067 |
| genetic variation analysis of pcv1 strains isolated from guangxi province of china in 2015. | porcine circovirus type 1 (pcv1) was discovered in 1974 as a contaminant of a porcine kidney (pk-15) cell line and was generally accepted to be nonpathogenic. but recently it was shown to cause lesions in experimentally infected pig fetuses. serological evidence and genetic studies suggested that pcv1 was widespread in domestic pigs. thus, the molecular epidemiology and genetic variation of pcv1 are still necessary to understand. | 2018 | 29415728 |
| suitability of the porcine aortic model for transcatheter aortic root repair. | to treat aortic valve disease and concomitant root disease with transcatheter techniques, 'composite graft' implants are required. our goal was to assess the suitability of the porcine aortic root for transcatheter root repair tests. | 2018 | 29415164 |
| observational analysis on inflammatory reaction to talc pleurodesis: small and large animal model series review. | talc pleurodesis has been associated with pleuropulmonary damage, particularly long-term damage due to its inert nature. the present model series review aimed to assess the safety of this procedure by examining inflammatory stimulus, biocompatibility and tissue reaction following talc pleurodesis. talc slurry was performed in rabbits: 200 mg/kg checked at postoperative day 14 (five models), 200 mg/kg checked at postoperative day 28 (five models), 40 mg/kg, checked at postoperative day 14 (five m ... | 2018 | 29403549 |
| the development of an interactive computer-based training program for timely and humane on-farm pig euthanasia. | with extensive knowledge and training in the prevention, management, and treatment of disease conditions in animals, veterinarians play a critical role in ensuring good welfare on swine farms by training caretakers on the importance of timely euthanasia. to assist veterinarians and other industry professionals in training new and seasoned caretakers, an interactive computer-based training program was created. it consists of three modules, each containing five case studies, which cover three dist ... | 2018 | 29400634 |
| in vivo assessment of a novel biodegradable ureteral stent. | to perform an in vivo assessment of a newly developed biodegradable ureteral stent (bus) produced with natural-based polymers. | 2018 | 29128964 |
| developmental regulation of the intestinal fgf19 system in domestic pigs. | fibroblast growth factor-19 (fgf19) is an emerging endocrine factor involved in the regulation of bile acid homeostasis and energy metabolism in rodents and humans. in pigs, however, the fgf19 system remains largely unexplored. this study was designed to investigate the developmental regulation of the fgf19 system in domestic pigs. samples of intestinal sections, liver, and plasma were collected from 24 pigs (n = 6) at four developmental stages (birth, pre-weaning, post-weaning, and adulthood). ... | 2018 | 29446652 |
| serological and virological survey of hepatitis e virus (hev) in animal reservoirs from uruguay reveals elevated prevalences and a very close phylogenetic relationship between swine and human strains. | hepatitis e virus (hev) infection is an issue of public health concern in high-income and non-endemic countries. increasing evidence supports the hypothesis of a zoonotic route as the main mode of infection in this epidemiological setting, since the transmission of genotypes hev-3 and hev-4 from reservoirs to humans has been demonstrated. in america, studies have confirmed the circulation of hev in pig herds but the zoonotic role of wild boars has never been evaluated. uruguay has a high burden ... | 2018 | 29291999 |
| feasibility study of a novel thoraco-abdominal aortic hybrid device (spider-graft) in a translational pig model. | the hybrid spider-graft consists of a proximal descending aortic stent graft and a conventional six branched dacron graft for open abdominal aortic repair. technical feasibility with regard to avoiding thoracotomy and extracorporeal circulation (ecc) during thoraco-abdominal aortic hybrid repair and peri-procedural safety of this novel device are unknown. | 2018 | 29290476 |
| diurnal rhythms in peripheral blood immune cell numbers of domestic pigs. | diurnal rhythms within the immune system are considered important for immune competence. until now, they were mostly studied in humans and rodents. however, as the domestic pig is regarded as suitable animal model and due to its importance in agriculture, this study aimed to characterize diurnal rhythmicity in porcine circulating leukocyte numbers. eighteen pigs were studied over periods of up to 50 h. cosinor analyses revealed diurnal rhythms in cell numbers of most investigated immune cell pop ... | 2018 | 29017838 |
| hepatitis e virus and related viruses in wild, domestic and zoo animals: a review. | hepatitis e is a human disease mainly characterized by acute liver illness, which is caused by infection with the hepatitis e virus (hev). large hepatitis e outbreaks have been described in developing countries; however, the disease is also increasingly recognized in industrialized countries. mortality rates up to 25% have been described for pregnant women during outbreaks in developing countries. in addition, chronic disease courses could be observed in immunocompromised transplant patients. wh ... | 2018 | 28944602 |
| first-time detection of porcine reproductive and respiratory syndrome virus (prrsv) infection in uruguay. | within the last two decades, several high-impact viruses have emerged in the global swine population, including porcine reproductive and respiratory syndrome virus (prrsv). in uruguay, the more recent serological survey for prrsv and other notifiable diseases such as aujeszky's disease virus (adv) and classical swine fever virus (csfv) dated from year 2000. the main purpose of this study was to update our information on the infection status of prrsv, adv and csfv in uruguayan pig herds, in order ... | 2018 | 29330937 |
| elevated proportions of deleterious genetic variation in domestic animals and plants. | a fraction of genetic variants segregating in any population are deleterious, which negatively impacts individual fitness. the domestication of animals and plants is associated with population bottlenecks and artificial selection, which are predicted to increase the proportion of deleterious variants. however, the extent to which this is a general feature of domestic species is unclear. here, we examine the effects of domestication on the prevalence of deleterious variation using pooled whole-ge ... | 2018 | 29325102 |
| gastrointestinal protists and helminths of habituated agile mangabeys (cercocebus agilis) at bai hokou, central african republic. | infectious diseases including those caused by parasites can be a major threat to the conservation of endangered species. there is thus a great need for studies describing parasite infections of these species in the wild. here we present data on parasite diversity in an agile mangabey (cercocebus agilis) group in bai hokou, dzanga-sangha protected areas (dspa), central african republic. we coproscopically analyzed 140 mangabey fecal samples by concentration techniques (flotation and sedimentation ... | 2018 | 29350404 |
| detection of β-lactamase encoding genes in feces, soil and water from a brazilian pig farm. | β-lactam antibiotics are widely used for the treatment of different types of infections worldwide and the resistance to these antibiotics has grown sharply, which is of great concern. resistance to β-lactams in gram-negative bacteria is mainly due to the production of β-lactamases, which are classified according to their functional activities. the aim of this study was to verify the presence of β-lactamases encoding genes in feces, soil, and water from a brazilian pig farm. different β-lactamase ... | 2018 | 29322334 |
| an assessment of shedding with the oral rabies virus vaccine strain spbn gasgas in target and non-target species. | a safety requirement for live vaccines is investigating possible shedding in recipients since the presence of replication competent vaccine in secretions could result in direct and indirect horizontal transmission. this is especially relevant for oral rabies vaccine baits that are deliberately distributed into the environment. in the current study, survival of an oral rabies virus vaccine, spbn gasgas, was examined in excretions from different target and non-target species; red fox, raccoon dog, ... | 2018 | 29325820 |