Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| virome and bacteriome characterization of children with pneumonia and asthma in mexico city during winter seasons 2014 and 2015. | acute asthma exacerbations and pneumonia are important causes of morbidity and mortality in children and may coexist in the same children, although symptom overlap may lead to difficulties in diagnosis. microbial and viral diversity and differential abundance of either may play an important role in infection susceptibility and the development of acute and chronic respiratory diseases. | 2018 | 29447223 |
| propionibacterium acnes has low susceptibility to chlorhexidine digluconate. | the skin bacterium propionibacterium acnes has been reported to be responsible for surgical site infections (ssis). skin disinfection before surgery therefore is of the utmost importance in the prevention of ssis caused by skin bacteria. | 2018 | 29447075 |
| preventing infection in shoulder surgery. | although rare, infection after shoulder surgery can represent a devastating complication. infection can negatively affect clinical outcomes, and eradication often requires a protracted treatment course. staphylococcus aureus, staphylococcus epidermidis, and propionibacterium acnes are among the most frequently isolated pathogens. perioperative measures can be implemented to reduce infection risk. here we review various perioperative practices and their efficacy at reducing infection after should ... | 2018 | 29444755 |
| propionibacterium acnesandstaphylococcus epidermidisolecranon bursitis/osteomyelitis: a case involving surgical and antibiotic treatment. | this report describes a 63-year-old generally healthy male with septic olecranon bursitis caused bypropionibacterium acnesthe patient sustained a small laceration after striking the posterior aspect of his left elbow on a metal railing when he was at a public swimming pool. we concluded thatp. acneswas not initially detected because cultures were only kept for 5 days. consequently, initial antibiotic treatment failed.p. acnesandstaphylococcus epidermidisgrew in a subsequent tissue culture. the i ... | 2018 | 29440139 |
| bacteriology and cefuroxime-resistance in endophthalmitis following cataract surgery before and after the introduction of prophylactic intracameral cefuroxime: a retrospective single-centre study. | intracameral cefuroxime as prophylaxis against postoperative endophthalmitis (poe) following cataract surgery was introduced in 1996 at st erik eye hospital. soon after the introduction of intracameral cefuroxime the rate of poe fell dramatically and a shift in the aetiology was noticed. | 2018 | 29432821 |
| dysbiosis of inferior turbinate microbiota is associated with high total ige levels in allergic rhinitis patients. | abnormalities in the human microbiota are associated with the etiology of allergic diseases. although disease site-specific microbiota may be associated with disease pathophysiology, the role of the nasal microbiota is unclear. we sought to characterize the microbiota of the site of allergic rhinitis, inferior turbinate, in subjects with allergic rhinitis (n=20) and healthy controls (n=12), and to examine the relationship of mucosal microbiota with disease occurrence, sensitized allergen number, ... | 2018 | 29426044 |
| topical delivery of erythromycin through cubosomes for acne. | topical delivery is an attractive route for local and systemic treatment. novel topical application has many advantages like avoids the gi-irritation, prevent the metabolism of drug in the liver and increase the bioavailability of the drug over the conventional dosage forms. the aim of present work was to prepared and characterized erythromycin encapsulated cubosomes using different concentration of glyceryl monooleate and poloxamer 407 by emulsification method. the prepared dispersion of cuboso ... | 2018 | 29424323 |
| [pseudarthrosis and construct failure after lumbar pedicle subtraction osteotomy : influence of biomechanics, surgical technique, biology and avoidance strategies]. | there are numerous factors that can lead to construct failure and pseudarthrosis after corrective pedicle subtraction osteotomy (pso) in the lumbar spine. frequently, several factors are of relevance in these problematic cases. this article attempts to explain the surgical, biomechanical and biological aspects that should be understood in order to minimize the risk of pseudarthrosis and construct failure. it addresses technical varieties of the pso procedure as well as the surgical technique, th ... | 2018 | 29411050 |
| a rationally designed multi-functional antibiotic for the treatment of drug-resistant acne. | acne is a multifactorial skin disease, underpinned by colonization of propionibacterium acnes and inflammation. the emergence of resistant propionibacterium acnes strains has affected the current acne treatment algorithm. this setback served as an impetus for rationally designing a library of next-generation antibiotics that exhibit a bactericidal effect on resistant propionibacterium acnes as well as exert an immunomodulatory function to reduce inflammation. in silico screening revealed that on ... | 2018 | 29409921 |
| propionibacterium acnes-derived extracellular vesicles promote acne-like phenotypes in human epidermis. | acne vulgaris is an inflammatory disease occurring in the pilosebaceous unit and is the most common skin condition in young people. a gram-positive bacterium, propionibacterium acnes (p. acnes), has been suspected to contribute to the development of acne. here, we report that p. acnes constitutively releases extracellular vesicles (evs) exhibiting typical ev morphology and size. moreover, the p. acnes-derived evs (pevs) can induce acne-like phenotypes in human epidermal keratinocytes and a recon ... | 2018 | 29409885 |
| propionibacterium acnes-derived insoluble immune complexes in sinus macrophages of lymph nodes affected by sarcoidosis. | propionibacterium acnes is thought to be a causative agent of sarcoidosis. patients with sarcoidosis have circulating immune complexes. we attempted to detect p. acnes-derived immune complexes in sarcoid lesions. | 2018 | 29401490 |
| anaerobic bacterial meningitis in adults. | anaerobic infection is a very uncommon condition in adult bacterial meningitis (abm), and its clinical characteristics have yet to be clarified. we enrolled 540 patients with culture-proven bacterial meningitis during a study period of 30 years (1986-2015), of whom 13 (2.4%) had anaerobic infections. these 13 patients were eight men and five women, aged 22-77 years. among them, 53.8% (7/13) had a postneurosurgical state as the preceding event, and 79.6% (10/13) had underlying medical conditions ... | 2018 | 29396061 |
| propionibacterium acnes strains differentially regulate the fate of th17 responses in the skin. | agak et al. demonstrate that different strains of propionibacterium acnes, a bacterium colonizing pilosebaceous units in healthy skin and acne, have the ability to induce t helper type 17 cells secreting either ifn-γ or il-10 and exhibiting either pathogenic or protective properties, respectively. this work contributes to growing evidence indicating that the phenotype of t helper type 17 cells is largely dependent on their microbiological environment. | 2018 | 29389326 |
| epidermal growth factor attenuated the expression of inflammatory cytokines in human epidermal keratinocyte exposed topropionibacterium acnes. | while the beneficial effects of topical epidermal growth factor (egf) on wound healing have been repeatedly reported, there are few reports about the effects of egf on inflammatory skin diseases including acne. | 2018 | 29386833 |
| platelet activation and aggregation by the opportunistic pathogen cutibacterium (propionibacterium) acnes. | cutibacterium (propionibacterium) acnes, considered a part of the skin microbiota, is one of the most commonly isolated anaerobic bacteria from medical implants in contact with plasma. however, the precise interaction of c. acnes with blood cells and plasma proteins has not been fully elucidated. herein, we have investigated the molecular interaction of c. acnes with platelets and plasma proteins. we report that the ability of c. acnes to aggregate platelets is dependent on phylotype, with a sig ... | 2018 | 29385206 |
| propionibacterium acnes abundance correlates inversely with staphylococcus aureus: data from atopic dermatitis skin microbiome. | the microbiome may influence disease severity in atopic dermatitis. the skin of atopic dermatitis patients and healthy individuals was sampled in a standardized manner and the microbial composition analysed using next-generation sequencing. optical density measurements were used to investigate bacterial growth under defined conditions in vitro. lesional skin from patients with atopic dermatitis had a higher abundance of s. aureus and reduced quantities of propionibacterium acnes and lawsonella c ... | 2018 | 29379979 |
| propionibacterium acnes suture contamination in arthroscopic rotator cuff repair: a prospective randomized study. | to examine the contamination rate of the anchor-suture and to determine the efficacy of 2 different surgical skin preparation solutions with or without a plastic adhesive drape from suture contamination in arthroscopic rotator cuff repair. | 2018 | 29373294 |
| a profile of propionibacterium acnes resistance and sensitivity at a tertiary dermatological centre in singapore. | propionibacterium acnes (p. acnes) is a key component in the pathogenesis of acne. both topical and oral antibiotics are key therapeutic options. unfortunately, antibiotic resistance is rapidly increasing globally. many countries have reported greater than 50% of p.acnes strains acquiring resistance to topical macrolides1-3. in singapore, antibiotic resistance rates of 8% in 19994rising to 14.9%5in 2007 were reported. we aimed to update the local prevalence of antibiotic resistance and identify ... | 2018 | 29368337 |
| prevalence of propionibacterium acnes in the glenohumeral compared with the subacromial space in primary shoulder arthroscopies. | we hypothesized that the prevalence of propionibacterium acnes in patients undergoing primary shoulder arthroscopy is equal in the glenohumeral space compared with the subacromial space. | 2018 | 29361412 |
| the human skin microbiome. | functioning as the exterior interface of the human body with the environment, skin acts as a physical barrier to prevent the invasion of foreign pathogens while providing a home to the commensal microbiota. the harsh physical landscape of skin, particularly the desiccated, nutrient-poor, acidic environment, also contributes to the adversity that pathogens face when colonizing human skin. despite this, the skin is colonized by a diverse microbiota. in this review, we describe amplicon and shotgun ... | 2018 | 29332945 |
| shunt nephritis: an increasingly unfamiliar diagnosis. | shunt nephritis is a rare, reversible immune-complex mediated complication of csf shunt infection that can progress to end-stage renal disease and even death if diagnosis is delayed. | 2018 | 29325951 |
| propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell apoptosis via the tlr2/jnk/mitochondrial-mediated pathway. | evidence suggests that intervertebral disc degeneration (ivdd) can be induced by propionibacterium acnes (p. acnes), although the underlying mechanisms are unclear. in this study, we analyzed the pathological changes in degenerated human intervertebral discs (ivds) infected with p. acnes. compared with p. acnes-negative samples, p. acnes-positive ivds showed increased apoptosis of nucleus pulposus cells (npcs) concomitant with severe ivdd. then, a p. acnes-inoculated ivd animal model was establi ... | 2018 | 29323102 |
| on revealing the gene targets of ebola virus micrornas involved in the human skin microbiome. | ebola virus, a negative-sense single-stranded rna virus, causes severe viral hemorrhagic fever and has a high mortality rate. histopathological and immunopathological analyses of ebola virus have revealed that histopathological changes in skin tissue are associated with various degrees of endothelial cell swelling and necrosis. the interactions of microbes within or on a host are a crucial for the skin immune shield. the discovery of micrornas (mirnas) in ebola virus implies that immune escape, ... | 2018 | 29312814 |
| susceptibility of enterococcus faecalis and propionibacterium acnes to antimicrobial photodynamic therapy. | bacterial resistance to available antibiotics nowadays is a global threat leading researchers around the world to study new treatment modalities for infections. antimicrobial photodynamic therapy (apdt) has been considered an effective and promising therapeutic alternative in this scenario. briefly, this therapy is based on the activation of a non-toxic photosensitizing agent, known as photosensitizer (ps), by light at a specific wavelength generating cytotoxic singlet oxygen and free radicals. ... | 2018 | 29253813 |