Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| propionibacterium acnes phylotypes and acne severity: an observational prospective study. | although a number of facts on the physiopathological mechanisms of acne are now well established, it is still unclear what triggers the severity of this inflammatory disease of the sebaceous follicle. thus, could the severity of the acne be somehow linked to different strains of its main bacterium, propionibacterium acnes? we know that there are several types of p. acnes, and a study (1) has recently shown that different strains of p. acnes could up-regulate or down-regulate in vitro inflammator ... | 2017 | 28295699 |
| the influence of direct inoculation of propionibacterium acnes on modic changes in the spine: evidence from a rabbit model. | modic changes (inflammatory-like changes visible on magnetic resonance imaging [mri] scans of a vertebral end plate) are common and are associated with low back pain, but their origin is unclear. to our knowledge, there have been no previous in vivo animal models of modic changes. we hypothesized that modic changes may be related to propionibacterium acnes. | 2017 | 28291179 |
| gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach. | there is evidence that nonalcoholic fatty liver disease (nafld) is affected by gut microbiota. therefore, we investigated its modifications in pediatric nafld patients using targeted metagenomics and metabolomics. stools were collected from 61 consecutive patients diagnosed with nonalcoholic fatty liver (nafl), nonalcoholic steatohepatitis (nash), or obesity and 54 healthy controls (ctrls), matched in a case-control fashion. operational taxonomic units were pyrosequenced targeting 16s ribosomal ... | 2017 | 27028797 |
| the evaluation of cultivable microbiota profile in patients with secondary endodontic infection before and after photo-activated disinfection. | secondary/persistent endodontic infection can be the outcome of failure of endodontic treatment. photo-activated disinfection (pad) can be a useful adjunct to mechanical and antimicrobial agents in eliminating endopathogenic microorganisms. in this study, we evaluated the effect of pad on diversity and count of microbiota related to secondary/persistent endodontic infections. | 2017 | 28249746 |
| stress hormone epinephrine (adrenaline) and norepinephrine (noradrenaline) effects on the anaerobic bacteria. | microbial endocrinology is a relatively new research area that already encompasses the anaerobes. stress hormones, epinephrine and norepinephrine, can affect the growth of anaerobic bacteria such as fusobacterium nucleatum, prevotella spp., porhyromonas spp., tanerella forsythia and propionibacterium acnes and can increase virulence gene expression, iron acquisition and many virulence factors of some anaerobic species such as clostridium perfringens, porphyromonas gingivalis and brachyspira pilo ... | 2017 | 28077337 |
| factors shaping the composition of the cutaneous microbiota. | from birth, we are constantly exposed to bacteria, fungi and viruses, some of which are capable of transiently or permanently inhabiting our different body parts as our microbiota. the majority of our microbial interactions occur during and after birth, and several different factors, including age, sex, genetic constitution, environmental conditions and lifestyle, have been suggested to shape the composition of this microbial community. propionibacterium acnes is one of the most dominant lipophi ... | 2017 | 27518483 |
| dynamic interactions between prophages induce lysis in propionibacterium acnes. | progress in next-generation sequencing technologies has facilitated investigations into microbial dynamics. an important bacterium in the dairy industry is propionibacterium freudenreichii, which is exploited to manufacture swiss cheeses. a healthy culture of these bacteria ensures a consistent cheese with formed 'eyes' and pleasant flavour profile, and the investigation of prophages and their interactions with these bacteria could assist in the maintenance of the standard of this food product. ... | 2017 | 27639668 |
| the cost effectiveness of vancomycin for preventing infections after shoulder arthroplasty: a break-even analysis. | increasing methicillin resistance and recognition of propionibacterium acnes as a cause of infection in shoulder arthroplasty has led to the adoption of local vancomycin powder application as a more effective method to prevent expensive periprosthetic infections. however, no study has analyzed the cost effectiveness of vancomycin powder for preventing infection after shoulder replacement. | 2017 | 27727049 |
| proteomic analysis of extracellular vesicles derived from propionibacterium acnes. | extracellular vesicle (ev) has been reported to conduct critical pathophysiological functions as an emerging mode of communication in bacteria. recently, propionibacterium acnes, an anaerobic gram-positive human commensal found in the skin and gastrointestinal tract, has drawn increasing attention as an underestimated pathogen in a variety of diseases. | 2017 | 27594576 |
| determination of the mutant prevention concentration and the mutant selection window of topical antimicrobial agents against propionibacterium acnes. | determination of the mutant prevention concentration (mpc) and the mutant selection window (msw) of antimicrobial agents used to treat pathogenic bacteria is important in order to apply effective antimicrobial therapies. here, we determined the mpcs of the major topical antimicrobial agents against propionibacterium acnes and staphylococcus aureus which cause skin infections and compared their msws. among the mpcs of nadifloxacin and clindamycin, the clindamycin mpc was determined to be the lowe ... | 2017 | 27764829 |
| proteomic and transcriptomic investigation of acne vulgaris microcystic and papular lesions: insights in the understanding of its pathophysiology. | the pathogenesis of acne vulgaris involves several phases including androgen-dependent hyper-seborrhea, colonization by propionibacterium acnes, and inflammation. recent investigations have shown that in fact p. acnes provokes the activation of the inflammasome present in macrophages and dendritic cells. this signaling pathway leads to excessive production of interleukin il-1β, a proinflammatory cytokine. nevertheless, these well-studied phenomena in acne fail to elucidate the mechanisms respons ... | 2017 | 27789243 |
| activity of electrical current in experimental propionibacterium acnes foreign-body osteomyelitis. | foreign-body-associated infections are often difficult to treat, given that the associated microorganisms are in a biofilm state. previously, we showed that a low-amperage direct electrical current (dc) reduces propionibacterium acnes biofilms formed on implant-associated materials in vitro in this study, low-amperage dc was compared to ceftriaxone treatment or no treatment in a novel rat femur model of foreign-body osteomyelitis. a platinum implant seeded with a p. acnes biofilm (10(7) cfu/cm(2 ... | 2017 | 27821457 |
| draft genome sequence of an erythromycin-resistant propionibacterium acnes isolate recovered from folliculitis of the scalp. | propionibacterium acnes is now well-known and recognized for its implication in the pathogenesis of acne vulgaris. here, we report the draft genome sequence of an erythromycin-resistant p. acnes strain isolated from a case of folliculitis of the scalp belonging to phylotype ia1 and sequence type 18 (st18). | 2017 | 28126936 |
| a multifactorial comparison of ternary combinations of essential oils in topical preparations to current antibiotic prescription therapies for the control of acne vulgaris-associated bacteria. | acne vulgaris, a chronic condition associated with overgrowth of propionibacterium acnes and staphylococcus epidermidis, is commonly treated with antibiotics. however, the emergence of antibiotic resistance has resulted in a need for alternative therapies. the aim of this study is to develop a topical preparation incorporating essential oils (eos) for use against acne-associated bacteria and assess its efficacy against prescription therapies dalacin t and stiemycin. antimicrobial screening of ro ... | 2017 | 28124400 |
| topical delivery of roxithromycin solid-state forms entrapped in vesicles. | recently, considerable interest developed in using newer/improved antibiotics for the treatment of acne vulgaris. during this study, different roxithromycin solid-state forms (i.e. crystalline and amorphous) were encapsulated into vesicle systems (niosomes, proniosomes, ufosomes and pro-ufosomes) for dermis targeted delivery. characterization of the vesicles was done with transmission electron microscopy, light microscopy, droplet size, droplet size distribution, ph, zeta-potential and entrapmen ... | 2017 | 28119103 |
| treatment effects of lysozyme-shelled microbubbles and ultrasound in inflammatory skin disease. | acne vulgaris is the most common skin disorder, and is caused by propionibacterium acnes (p. acnes) and can induce inflammation. antibiotic therapy often needs to be administered for long durations in acne therapy, which results in extensive antibiotic exposure. the present study investigated a new treatment model for evaluating the antibacterial effects of lysozyme (ly)-shelled microbubbles (mbs) and ultrasound (us)-mediated ly-shelled mbs cavitation against p. acnes both in vitro and in vivo, ... | 2017 | 28117399 |
| inhibition of propionibacterium acnes lipase activity by the antifungal agent ketoconazole. | the common skin disease acne vulgaris is caused by propionibacterium acnes. a lipase secreted by this microorganism metabolizes sebum and the resulting metabolites evoke inflammation in human skin. the antifungal drug ketoconazole inhibits p. acnes lipase activity. we previously showed that the drug also inhibits the growth of p. acnes. thus, ketoconazole may serve as an alternative treatment for acne vulgaris, which is important because the number of antibiotic-resistant p. acnes strains has be ... | 2017 | 28111792 |
| characterisation of microbial communities within aggressive prostate cancer tissues. | an infectious aetiology for prostate cancer has been conjectured for decades but the evidence gained from questionnaire-based and sero-epidemiological studies is weak and inconsistent, and a causal association with any infectious agent is not established. we describe and evaluate the application of new technology to detect bacterial and viral agents in high-grade prostate cancer tissues. the potential of targeted 16s rrna gene sequencing and total rna sequencing was evaluated in terms of its uti ... | 2017 | 28101126 |
| development of actinobacterial resources for functional cosmetics. | actinobacteria usually produce different functional compounds for various applications. | 2017 | 28097821 |
| skin microbiome and acne vulgaris: staphylococcus, a new actor in acne. | propionibacterium acnes (p. acnes), the sebaceous gland and follicular keratinocytes are considered the three actors involved in the development of acne. this exploratory study investigated the characteristics of the skin microbiota in subjects with acne and determined microbiota changes after 28 days of application of erythromycin 4% or a dermocosmetic. skin microbiota were collected under axenic conditions from comedones, papulo-pustular lesions and non-lesional skin areas from subjects with m ... | 2017 | 28094874 |
| bacteriological profile of ocular surface flora in meibomian gland dysfunction. | to compare the bacteriological profile of meibomian gland secretion and conjunctival cul-de-sac in subjects with and without meibomian gland dysfunction (mgd). | 2017 | 28093340 |
| future surgery after revision shoulder arthroplasty: the impact of unexpected positive cultures. | the clinical implications and treatment of unexpected positive cultures (upcs) in revision shoulder arthroplasty are not well defined. the purpose of this study was to describe results of patients with and without upcs after revision shoulder arthroplasty. | 2017 | 28087166 |
| multiple activities of punica granatum linne against acne vulgaris. | acne is a common skin condition with sebum overproduction, hyperkeratosis, propionibacterium acnes (p. acnes) and staphylococcus aureus, and inflammation. punica granatum (pomegranate) is well-known for its anti-inflammatory effects; however, few studies have discussed the anti-acne effects of pomegranate. in this study, we found that pomegranate extract (pg-e) significantly reduced p. acnes-induced edema in wistar rat ears. therefore, an evaluation platform using multiple pathogenic mechanisms ... | 2017 | 28085116 |
| performance of two blood culture systems to detect anaerobic bacteria. is there any difference? | we studied the performance characteristics of two blood culture (bc) bottles/systems, (i) bact/alert-fn plus/3d (biomérieux, marcy l'étoile, france) and (ii) bactec-lytic/9000 (becton dickinson, sparks, usa) for detection of growth and time-to-positivity (ttp) against a balanced and diverse collection of anaerobic bacterial strains (n = 48) that included reference strains (n = 19) and clinical isolates (n = 29) of 32 species (15 gram-negative and 17 gram-positive). standard suspension of bacteri ... | 2017 | 28279857 |
| neer award 2017: a rapid method for detecting propionibacterium acnes in surgical biopsy specimens from the shoulder. | propionibacterium (p) acnes infection of the shoulder after arthroplasty is a common and serious complication. current detection methods for p acnes involve anaerobic cultures that require prolonged incubation periods (typically 7-14 days). we have developed a polymerase chain reaction (pcr)-restriction fragment length polymorphism (rflp) approach that sensitively and specifically identifies p acnes in tissue specimens within a 24-hour period. | 2017 | 27887873 |
| rhodomyrtone inhibits lipase production, biofilm formation, and disorganizes established biofilm in propionibacterium acnes. | virulence enzymes and biofilm a play crucial role in the pathogenesis of propionibacterium acnes, a major causative agent of acne vulgaris. in the present study, the effects of rhodomyrtone, a pure compound identified from rhodomyrtus tomentosa (aiton) hassk. leaves extract against enzyme production and biofilm formation production by 5 clinical isolates and a reference strain were evaluated. the degree of hydrolysis by both lipase and protease enzymes significantly decreased upon treatment with ... | 2017 | 27923605 |
| risk factors for propionibacterium acnes infection after neurosurgery: a case-control study. | propionibacterium acnes is increasingly known as a causative organism for post-neurosurgical infection; however, no clinical studies have examined the risk factors associated with p. acnes infections. clinical data obtained from 14 cases of p. acnes infection and 28 controls infected with other pathogens were analyzed. craniotomy, malignancy, and prolonged duration of operation were significantly associated with the onset of p. acnes infection. no fatal cases were reported. | 2017 | 27889246 |
| nonunion after clavicle osteosynthesis: high incidence of propionibacterium acnes. | the objective of this study was to review the etiology of clavicle nonunions after osteosynthesis and investigate the outcomes of a treatment with a single-stage revision. | 2017 | 27984454 |
| prevention of propionibacterium acnes biofilm formation in prosthetic infections in vitro. | the role of propionibacterium acnes in shoulder arthroplasty and broadly in orthopedic prosthetic infections has historically been underestimated, with biofilm formation identified as a key virulence factor attributed to invasive isolates. with an often indolent clinical course, p acnes infection can be difficult to detect and treat. this study investigates absorbable cements loaded with a broad-spectrum antibiotic combination as an effective preventive strategy to combat p acnes biofilms. | 2017 | 27989720 |
| frequency of propionibacterium acnes infection in prostate glands with negative biopsy results is an independent risk factor for prostate cancer in patients with increased serum psa titers. | propionibacterium acnes has recently been implicated as a cause of chronic prostatitis and this commensal bacterium may be linked to prostate carcinogenesis. the occurrence of intracellular p. acnes infection in prostate glands and the higher frequency of p. acnes-positive glands in radical prostatectomy specimens from patients with prostate cancer (pca) than in those from patients without pca led us to examine whether the p. acnes-positive gland frequency can be used to assess the risk for pca ... | 2017 | 28081259 |
| modern management of acne. | acne is a chronic inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production; altered keratinisation; bacterial colonisation of hair follicles on the face, neck, chest and back by propionibacterium acnes; and an inflammatory response in the skin. the exact way these processes interact and the order in which they occur in the pathogenesis of acne are still unclear. scarring that occurs from acne, particularly severe acne, can persist a lifetime and h ... | 2017 | 28076744 |
| clinical impact of positive propionibacterium acnes cultures in orthopedic surgery. | the clinical significance of a positive culture to propionibacterium acnes in orthopedic specimens remains unclear, whether about its role as a contaminant or a pathogen, or its impact as a coinfectant. therefore, we performed a retrospective study to provide a more accurate description of the clinical impact of p. acnes in an orthopedic population aiming to determine: 1) if there is a clinical difference between p. acnes infection and contamination? 2) if there is a clinical difference between ... | 2017 | 28065868 |
| propionibacterium acnes endocarditis: a case series. | propionibacterium acnes remains a rare cause of infective endocarditis (ie). it is challenging to diagnose due to the organism's fastidious nature and the indolent presentation of the disease. the purpose of this study was to describe the clinical presentation and management of p. acnes ie with an emphasis on the methods of diagnosis. | 2017 | 28057559 |
| bacteriophage formulated into a range of semisolid and solid dosage forms maintain lytic capacity against isolated cutaneous and opportunistic oral bacteria. | resistance of bacteria to antimicrobial agents is of grave concern. further research into the development of bacteriophage as therapeutic agents against bacterial infections may help alleviate this problem. | 2017 | 28033675 |
| recognition of propionibacterium acnes by human tlr2 heterodimers. | propionibacterium acnes has been considered as a crucial contributor to the pathogenesis of acne vulgaris. the interaction between p. acnes and the host is mainly mediated by toll like receptor (tlr) 2 recognition. tlr2 homodimers recognize p. acnes in mice, but here we describe the prerequisite of tlr2/1 and tlr2/6 heterodimers in human cells for p. acnes recognition. p. acnes-induced nf-κb and ap-1activation observed in hek htlr2-transfected but not control cells confirmed the specificity of t ... | 2017 | 28024924 |
| epidemiology of deep surgical site infections after pediatric spinal fusion surgery. | single-institution, retrospective case series. | 2017 | 27306257 |
| clinical features of anaerobic orthopaedic infections. | some patient populations and types of orthopaedic surgery could be at particular risk for anaerobic infections. in this retrospective cohort study of operated adult patients with infections from 2004 to 2014, we assessed obligate anaerobes and considered first clinical infection episodes. anaerobes, isolated from intra-operative samples, were identified in 2.4% of 2740 surgical procedures, of which half (33/65; 51%) were anaerobic monomicrobial infections. propionibacterium acnes, a penicillin a ... | 2017 | 27581503 |
| assessment of anaerobic blood cultures in pediatric oncology patients. | the routine use of a single aerobic bottle for blood culture in pediatric patients has become commonplace, as anaerobic bacteria are not frequently involved in clinically significant infections. the aim of this study was to assess the usefulness of routinely performing anaerobic blood cultures in pediatric oncology patients. | 2017 | 27221161 |
| is it time to switch on or off the green light for ultraviolet-induced red fluorescence as a surrogate marker for propionibacterium acnes in vivo? | 2017 | 27307204 | |
| induction of pulmonary granuloma formation by propionibacterium acnes is regulated by myd88 and nox2. | sarcoidosis is characterized by noncaseating granulomas with an unknown cause that present primarily in the lung. propionibacterium acnes, an immunogenic commensal skin bacterium involved in acne vulgaris, has been implicated as a possible causative agent of sarcoidosis. here, we demonstrate that a viable strain of p. acnes isolated from a patient with sarcoidosis and instilled intratracheally into wild-type mice can generate pulmonary granulomas similar to those observed in patients with sarcoi ... | 2017 | 27607191 |
| infections following arthroscopic rotator cuff repair: incidence, risk factors, and prophylaxis. | the primary aim of the present study was to determine the incidence of infections following arthroscopic rotator cuff repair in a single department over a 10-year period. secondary goals included the evaluation of potential risk factors for infections and to investigate the efficacy of perioperative antibiotic prophylaxis in the reduction of infectious complications. | 2017 | 27342982 |
| cross-sectional pilot study of antibiotic resistance in propionibacterium acnes strains in indian acne patients using 16s-rna polymerase chain reaction: a comparison among treatment modalities including antibiotics, benzoyl peroxide, and isotretinoin. | antibiotic resistance is a worldwide problem in acne patients due to regional prescription practices, patient compliance, and genomic variability in propionibacterium acnes, though the effect of treatment on the resistance has not been comprehensively analyzed. | 2017 | 26955094 |
| strain-level differences in porphyrin production and regulation in propionibacterium acnes elucidate disease associations. | propionibacterium acnes is an important skin commensal, but it is also considered a pathogenic factor in several diseases including acne vulgaris, the most common skin disease. while previous studies have revealed p. acnes strain-level differences in health and disease associations, the underlying molecular mechanisms remain unknown. recently, we demonstrated that vitamin b12 supplementation increases p. acnes production of porphyrins, a group of proinflammatory metabolites important in acne dev ... | 2017 | 27303708 |
| a rare case of delayed onset capsular block syndrome managed using 25-gauge vitrector. | we report a case of delayed onset capsular block syndrome in a patient 6 years after undergoing cataract surgery. ocular examination revealed marked diminution of vision accompanied with a collection of milky fluid between the intraocular lens and posterior capsule. to treat and to understand the pathology of the condition, aspiration of fluid using 25-gauge vitrector through pars plana was done, and contents sent for microbiological analysis which did not reveal any growth. postoperative period ... | 2017 | 26903727 |
| propionibacterium acnes infection after shoulder surgery. | propionibacterium acnes has been implicated as a cause of infection following shoulder surgery, may occur up to 2 years after the index operation and has been shown to be responsible for up to 56% of shoulder infections after orthopedic implant. male patients within the population undergoing shoulder surgery are particularly at risk, especially if their shoulder surgery involved prosthesis or was posttraumatic. p. acnes infection can be difficult to diagnose clinically and laboratory techniques ... | 2017 | 26622132 |
| inhibition of lipase and inflammatory mediators by chlorella lipid extracts for antiacne treatment. | acne vulgaris is a chronic inflammatory disease, and its treatment is challenging due to the multifactorial etiology and emergence of antibiotic-resistant propionibacterium acnes strains. this study was focused to reduce antibiotics usage and find an alternate therapeutic source for treating acne. lipid extracts of six chlorella species were tested for inhibition of lipase, reactive oxygen species (ros) production, cytokine production using p. acnes (microbial type culture collection 1951). lipa ... | 2017 | 25709963 |
| preliminary evidence for vitamin d deficiency in nodulocystic acne. | acne vulgaris is a chronic inflammatory disease, and hormonal influences, follicular plugging and follicular hyperkeratinization, increased sebum secretion, propionibacterium acnes colonization, and inflammation are involved in its pathogenesis. recently, a significant body of evidence has accumulated that describes the comedolytic properties of vitamin d and its roles as a modulator of the immune system, a regulator of the proliferation and differentiation of sebocytes and keratinocytes, and as ... | 2017 | 26413187 |
| propionibacterium acnes endophthalmitis in ahmed glaucoma valve. | to report a case of propionibacterium acnes endophthalmitis in a patient with an ahmed glaucoma valve. | 2017 | 28226111 |
| primary intraocular lymphoma: another great masquerader. | to describe diverse and atypical presentations of the most common masquerader in neoplastic masquerade syndromes. | 2017 | 28221644 |
| late onset posttraumatic propionibacterium acnes endophthalmitis. | to report a case of late onset posttraumatic endophthalmitis secondary to propionibacterium acnes infection. | 2017 | 28221490 |
| clinicobacteriological study of acne vulgaris. | the aetiological relationship propionibacterium acnes in acne vulgaris has been suggested. a clinicobacteriological study in 45 patients suffering from acne vulgaris was conducted for the first time in indian patients. p acnes could be isolated from 18 (40.0%) and other propionibacterium species from 9 (20.0%) of the 45 patients studied. no correlation of culture positivity with the sex of the patient or duration and grade of the disease could be established, p acnes antibodies were, tested for ... | 2017 | 28223653 |
| mikania glomerata sprengel extract and its major compound ent-kaurenoic acid display activity against bacteria present in endodontic infections. | the search for new, effective and safe antimicrobial compounds from plant sources has continued to play an important role in the maintenance of human health since ancient times. such compounds can be used to help to eradicate microorganisms from the root canal system, preventing/healing periapical diseases. mikania glomerata (spreng.), commonly known as "guaco," is a native climbing plant from brazil that displays a wide range of pharmacological properties. many of its activities have been attri ... | 2017 | 28627377 |
| b cell cross-epitope of propionibacterium acnes and actinobacillus pleuropneumonia selected by phage display library can efficiently protect from actinobacillus pleuropneumonia infection. | contagious porcine pleuropneumonia (cpp), caused by actinobacillus pleuropneumoniae (app), is a highly transmissible and fatal respiratory illness that causes tremendous economic losses for the pig breeding industry worldwide. propionibacterium acnes (pa) has a strong cross-reaction with anti-app1 and anti-app5 serum and can efficiently prevent app infection, which was fortuitously found in researching the differential gene between the different app serotypes. there seems to be some natural cros ... | 2017 | 28622855 |
| anaerobic bacteria growth in the presence of cathelicidin ll-37 and selected ceragenins delivered as magnetic nanoparticles cargo. | cationic antibacterial peptides (caps) and synthetic molecules mimicking the amphiphilic structure of caps, such as ceragenins, are promising compounds for the development of new antimicrobials. | 2017 | 28747178 |
| [effect of silver nanoparticles on anaerobic bacteria]. | the aim was to evaluate the antibacterial effect of silver nanoparticles on anaerobic bacteria. | 2017 | 28467592 |
| comparative antimicrobial efficacy of selected root canal irrigants on commonly isolated microorganisms in endodontic infection. | this study aims to evaluate and compare the antimicrobial efficacy of three selected root canal irrigants (biopure mtad, metronidazole, aztreonam) against microbes commonly isolated from polymicrobial microbiota of root canal infection. | 2017 | 28435359 |
| identification and characterization of multifunctional cationic and amphipathic peptides from soybean proteins. | in this study, we identified and chemically synthesized three cationic and amphipathic peptides (glycinin-17, bcas-16, and bcbs-11) from soybean proteins. these peptides had high isoelectric points, high positive net charges, and included multiple hydrophobic amino acids. subsequently, we identified multiple functions of these peptides, including antimicrobial, lipopolysaccharide-neutralizing, and angiogenic activities, and examined their cytotoxic activities against mammalian red blood cells. g ... | 2017 | 28459130 |
| propionibacterium acnes-associated neurosarcoidosis: a case report with review of the literature. | a 56-year-old woman with a 3-year history of hydrocephalus and ventriculo-peritoneal shunt placement, presented with worsening altered level of consciousness for 2 days. imaging studies showed severe ventriculomegaly involving the lateral and third ventricles with multiple septated cysts noted in the lateral ventricles predominantly near the frontal horns. histopathologic examination of the excised brain lesion revealed choroid plexus tissue and adjacent cerebral parenchyma with several non-case ... | 2017 | 28856748 |
| whole-body microbiota of sea cucumber (apostichopus japonicus) from south korea for improved seafood management. | sea cucumber (apostichopus japonicus) is a popular seafood source in asia, including south korea, and its consumption has recently increased with recognition of its medicinal properties. however, because raw sea cucumber contains various microbes, its ingestion can cause foodborne illness. therefore, analysis of the microbiota in the whole body of sea cucumber can extend our understanding of foodborne illness caused by microorganisms and help to better manage products. we collected 40 sea cucumb ... | 2017 | 28851208 |
| utility of strain typing of propionibacterium acnes in central nervous system and prosthetic joint infections to differentiate contamination from infection: a retrospective cohort. | the study aimed to retrospectively assess if strain typing of propionibacterium acnes could help to distinguish between infection and contamination in isolates recovered from the central nervous system (cns) and prosthetic joints (pjs). this was a retrospective cohort of all propionibacterium species isolates from the barnes-jewish hospital (st louis, mo, usa) clinical microbiology laboratory from 2011 to 2014. available frozen isolates were recovered, and strain type (ia-1, ia-2, ib, ii, iii, o ... | 2017 | 28842758 |
| evaluation of anti-inflammatory and antimicrobial activity of ahpl/aycap/0413 capsule. | conventional therapeutic agents used for treatment of acne are associated with various adverse effects necessitating development of safe and effective alternative therapeutic agents. in this context, a polyherbal formulation ahpl/aycap/0413 was developed for treatment of acne. | 2017 | 28827969 |
| cutibacteriumacnes septic arthritis of the nonoperated knee: a case report. | cutibacterium (propionibacterium) acnes , a gram-positive bacillus with low pathogenicity, is an uncommon but known cause of prosthetic joint infections, particularly related to shoulder surgery. c. acnes , however, is an extremely rare pathogen in the nonoperated knee joint. this report details an uncommon case of c. acnes septic knee arthritis after multiple intra-articular steroid injections in a 56-year-old male patient. after an indolent presentation and late diagnosis, the patient underwen ... | 2017 | 28825032 |
| in vitro anti-acne activity of phytoactives from the stem bark of artocarpus hirsutus lam. and characterisation of pyranocycloartobiloxanthone a as a mixture of two anomers. | this study is aimed to isolate the phytoactives from the stem bark of artocarpus hirsutus and evaluate their in vitro anti-acne activity. the ethanolic stem bark extract of a. hirsutus provided two major phytoactive constituents: (i) pyranocycloartobiloxanthone a, (1) and (ii) artonine e, (2) whose structures were determined by nmr and ms spectroscopic analysis. the present study is the first to report compound 1 as a mixture of two anomers (α and β), approximately 70:30 ratio. both compounds 1 ... | 2017 | 28820275 |
| description of actinokineospora acnipugnans sp. nov., an actinomycete isolated from soil, showing potential uses in cosmetics. | during isolation of soil bacteria having antibacterial functions, an aerobic, gram-stain-positive, oxidase-negative, catalase-positive bacterium, designated strain r434t, was isolated. strain r434t showed antimicrobial activity against propionibacterium acnes and staphylococcus epidermidis and significant enzyme-inhibitory capability. the diagnostic diamino acid of the cell-wall peptidoglycan was meso-diaminopimelic acid, and the whole-cell sugars were galactose, arabinose and glucose. phylogene ... | 2017 | 28820111 |
| what is new in the pathophysiology of acne, an overview. | acne is a chronic inflammatory disease of the pilosebaceous unit. its pathophysiology includes hyperseborrhoea, abnormal follicular keratinization and propionibacterium acnes proliferation in the pilosebaceous unit. recent research has shed some new light on the involvement of the sebaceous gland, as well as on the pro-inflammatory activity of the cutaneous microbiome. during puberty, alteration of the sebaceous lipid profile, called dysseborrhoea, stress, irritation, cosmetics and potential die ... | 2017 | 28805938 |
| sebocytes contribute to skin inflammation by promoting the differentiation of th17 cells. | the main function of sebocytes is considered to be the lipid production for moisturizing the skin. however, it became recently apparent that sebocytes release chemokines and cytokines and respond to pro-inflammatory stimuli as well as presence of bacteria. | 2017 | 28799643 |
| conjunctival bacteria flora of glaucoma patients during long-term administration of prostaglandin analog drops. | to investigate the effects of the long-term use of prostaglandin analogs for glaucoma treatment on the indigenous flora of the conjunctiva. | 2017 | 28796877 |
| propionibacterium acnes and the th1/th17 axis, implications in acne pathogenesis and treatment. | acne vulgaris is one of the most commonly seen conditions and the immunological link is a topic of active research. recently, the th17 pathway has been found to play a pivotal role in acne. the adaptive immune response toward propionibacterium acnes leads to activation of th17 axis. consequently, the th17 cytokines (il-17, il-1 β, il-6, and tumor growth factor, in turn, activate the various pathogenic steps in acne. drugs such as vitamin d3 and isotretinoin which target the th17 pathway may offe ... | 2017 | 28794550 |
| synchronizing pharmacotherapy in acne with review of clinical care. | acne is a chronic inflammatory skin disease that involves the pathogenesis of four major factors, such as androgen-induced increased sebum secretion, altered keratinization, colonization of propionibacterium acnes, and inflammation. several acne mono-treatment and combination treatment regimens are available and prescribed in the indian market, ranging from retinoids, benzoyl peroxide (bpo), anti-infectives, and other miscellaneous agents. although standard guidelines and recommendations overvie ... | 2017 | 28794543 |
| non-antibiotic isotretinoin treatment differentially controls propionibacterium acnes on skin of acne patients. | emergence and potential transfer of antibiotic resistance in skin microorganisms is of current concern in medicine especially in dermatology contexts where long term treatment with antibiotics is common. remarkably, non-antibiotic therapy in the form of isotretinoin - a non-antimicrobial retinoid is effective at reducing or eradicating the anaerobe propionibacterium acnes which is causally involved in the complex pathogenesis of acne vulgaris. this study measured the extent of colonization of p. ... | 2017 | 28790988 |
| periprosthetic joint infection of shoulder arthroplasties: diagnostic and treatment options. | periprosthetic joint infection (pji) is one of the most frequent reasons for painful shoulder arthroplasties and revision surgery of shoulder arthroplasties.cutibacterium acnes (propionibacterium acnes)is one of the microorganisms that most often causes the infection. however, this slow growing microorganism is difficult to detect. this paper presents an overview of different diagnostic test to detect a periprosthetic shoulder infection. this includes nonspecific diagnostic tests and specific te ... | 2017 | 29423407 |
| [progress on propionibacterium acnes and degenerative intervertebral disc]. | the mechanism of degenerative intervertebral disc is very complex, which may be associated with multiple factors such as the mechanical stress force injury of intervertebral disc, nutritional deficiency, inflammatory stimulation, etc. recently, many studies detected propionibacterium acnes(p. acnes) in degenerative intervertebral disc and supposed p. acnes was associated with degenerative intervertebral disc. here, the papers related to p. acnes and degenerative intervertebral disc were reviewed ... | 2017 | 29417784 |
| over a decade of reca and tly gene sequence typing of the skin bacterium propionibacterium acnes: what have we learnt? | the gram-positive, anaerobic bacteriumpropionibacterium acnesforms part of the normal microbiota on human skin and mucosal surfaces. while normally associated with skin health,p. acnesis also an opportunistic pathogen linked with a range of human infections and clinical conditions. over the last decade, our knowledge of the intraspecies phylogenetics and taxonomy of this bacterium has increased tremendously due to the introduction of dna typing schemes based on single and multiple gene loci, as ... | 2017 | 29267255 |
| glenohumeral joint sepsis after joint injection through a new tattoo. | we report a case of propionibacterium acnes septic arthritis of a shoulder following two joint access procedures. methodical investigation of these two procedures was performed using the joint commission root cause analysis matrix, which involved examination of protocols, interviews with technologists and physicians, and inspection of the procedure rooms and equipment. no procedural error or other causal factor for infection was found other than the injection through a five day-old tattoo during ... | 2017 | 29296168 |
| a case of relapsing polychondritis mimicking hemophagocytic lymphohistiocytosis after propionibacterium acnes infection. | we describe a 69-year-old man who presented with a right sternocleidomastoid intramuscular abscess that grew propionibacterium acnes. despite initial improvement with antibiotics, he subsequently developed signs and symptoms fulfilling diagnostic criteria for hemophagocytic lymphohistiocytosis (hlh)-fevers, cytopenias, hyperferritinemia, splenomegaly, and low natural killer cell activity. the patient improved spontaneously but at outpatient follow-up complained of erythema over the bridge of his ... | 2017 | 29280824 |
| bacterial diversity in feline conjunctiva based on 16s rrna gene sequence analysis: a pilot study. | changes in the microbial populations in the conjunctival sacs of animals have traditionally been evaluated using conventional microbiology techniques. the goal of this study was to examine the suitability of a methodology which may reveal a previously unknown microbiome inhabiting feline conjunctival membranes. in the present study, we determined the microbial diversity in feline conjunctivas based on 16s rrna gene sequence analysis. five taxa not described earlier in veterinary ophthalmology (i ... | 2017 | 29279847 |
| topographical diversity of common skin microflora and its association with skin environment type: an observational study in chinese women. | this study evaluated cutaneous microbial distribution, and microbial co-occurrence at different body sites and skin environments in chinese women (39.6 ± 11.9 years, n = 100) during the winter season. microbial distribution (propionibacterium acnes, staphylococcus aureus, staphylococcus epidermidis, lactobacillus, pseudomonadaceae, and malassezia furfur), association with biomarkers (antimicrobial peptides: ll-37, β-defensins [hbd-2, hbd-3]), and claudin-1) and skin biophysical parameters (trans ... | 2017 | 29273721 |
| infection rate after cranial neurosurgical procedures: a prospective single-center study. | to determine infection rate (ir) and to identify modifiable risk factors (rf) in cranial neurosurgery in a neurosurgical department for tertiary referral as part of an infection control surveillance to reduce surgical site infections (ssi). | 2017 | 29269070 |
| culture-dependent approaches to explore the prevalence of root canal pathogens from endodontic infections. | endodontic infections are considered to be caused by the presence of various microorganisms within the root canal system. recognition of this microbiota contributes to the successful treatment of infected root canals. this study investigated the microorganisms associated with primary and secondary endodontic infections via culture methods, biochemical tests, and molecular approaches in an iranian population. microbial specimens were collected from 36 patients with primary endodontic infection an ... | 2017 | 29267669 |
| disseminated propionibacterium acnes infection in a 42-year-old hiv-positive man. | 2017 | 29241870 | |
| long-term administration of oral macrolides for acne treatment increases macrolide-resistant propionibacterium acnes. | macrolide-resistant propionibacterium acnes are frequently isolated from patients with acne vulgaris, and the most resistant isolates (>90% resistance) have the 23s rrna mutation. an increase in resistant p. acnes with this mutation is thought to be caused by the inappropriate use of antimicrobials. therefore, we studied the mutation frequency of macrolide resistance in p. acnes in vitro. when p. acnes mutants were exposed to clarithromycin after being incubated in broth without antimicrobials, ... | 2017 | 29235673 |
| antibiotic treatment of propionibacterium acnes endocarditis. | 2017 | 28782652 | |
| fast 2d nmr spectroscopy for in vivo monitoring of bacterial metabolism in complex mixtures. | the biological toolbox is full of techniques developed originally for analytical chemistry. among them, spectroscopic experiments are very important source of atomic-level structural information. nuclear magnetic resonance (nmr) spectroscopy, although very advanced in chemical and biophysical applications, has been used in microbiology only in a limited manner. so far, mostly one-dimensional (1)h experiments have been reported in studies of bacterial metabolism monitored in situ. however, low sp ... | 2017 | 28769889 |
| the colonisation of the glenohumeral joint by propionibacterium acnes is not associated with frozen shoulder but is more likely to occur after an injection into the joint. | our aim was to investigate the prevalence of propionibacterium (p.) acnes in the subcutaneous fat and capsule of patients undergoing shoulder surgery for frozen shoulder or instability. | 2017 | 28768784 |
| two-stage reimplantation for the treatment of deep infection after shoulder arthroplasty. | two-stage reimplantation is the most common treatment modality considered for periprosthetic shoulder infection (psi). most studies to date have reported on a relatively small number of shoulders. the purpose of this study was to determine the outcome of 2-stage reimplantation for psi in terms of both eradication of infection and restoration of function. | 2017 | 28751093 |
| characterization of a propionibacterium acnes surface protein as a fibrinogen-binding protein. | propionibacterium acnes (p. acnes) is a major skin-associated bacterium that was long considered commensal, until several studies revealed it to be an opportunistic pathogen. we investigated the ability of p. acnes surface proteins to recognize ecm proteins and showed that a 58 kda p. acnes surface protein was specifically recognized by human fibrinogen (hfg). the 58 kda protein was further characterized by two-dimensional (2-d) electrophoresis and maldi-tof as a p. acnes host cell-surface attac ... | 2017 | 28743910 |
| preoperative doxycycline does not decolonize propionibacterium acnes from the skin of the shoulder: a randomized controlled trial. | propionibacterium acnes is frequently cultured in patients undergoing both primary and revision shoulder surgery. the purpose of this study was to evaluate the efficacy and safety of preoperative oral administration of doxycycline in decreasing the colonization of skin around the shoulder by p. acnes. | 2017 | 28734717 |
| optimization of genotypic and biochemical methods to profile p. acnes isolates from a patient population. | propionibacterium acnes is a key factor in the pathogenesis of acne vulgaris, although currently it is also being associated with medical-device infections. the aim of this work was to validate a safe and quick identification and typing of 24 clinical isolates of propionibacterium acnes, applying a range of biochemical as well as genetic methods, and investigating the pathogenic potential to associate the different types with human health. rapd-pcrs revealed the existence of two discernible clus ... | 2017 | 28732695 |
| involvement of adenosine triphosphate-binding cassette subfamily b member 1 in the augmentation of triacylglycerol excretion by propionibacterium acnes in differentiated hamster sebocytes. | an onset of acne, a common inflammatory skin disease, is associated with excess sebum production and secretion in sebaceous glands. because propionibacterium acnes has been reported to augment intracellular sebum accumulation in sebaceous glands in hamsters, it remains unclear whether p. acnes influences sebum secretion from differentiated sebocytes. both p. acnes culture media (acnes73-cm) and formalin-killed p. acnes (f-acnes73) dose-dependently increased the extracellular levels of triacylgly ... | 2017 | 28714181 |
| the distribution of infection with propionibacterium acnes is equal in patients with cervical and lumbar disc herniation. | cervical and back pains are important clinical problems affecting human populations globally. it is suggested that propionibacterium acnes (p. acnes) is associated with disc herniation. the aim of this study is to evaluate the distribution of p. acnes infection in the cervical and lumbar disc material obtained from patients with disc herniation. | 2017 | 28712017 |
| current treatments of acne: medications, lights, lasers, and a novel 650-μs 1064-nm nd: yag laser. | the treatment of acne, especially severe acne, remains a challenge to dermatologists. therapies include retinoids, antibiotics, hormones, lights, lasers, and various combinations of these modalities. acne is currently considered a chronic rather than an adolescent condition. the appropriate treatment depends on the patient and the severity of disease. the purpose of this study was to review current therapies for acne of all severities and to introduce the 650-μs 1064-nm laser for the treatment o ... | 2017 | 28703382 |
| [diagnosis of periprosthetic joint infection of shoulder arthroplasties]. | periprosthetic joint infection of shoulder arthroplasties is one of the most frequent reasons for pain and revision surgery of shoulder arthroplasties. propionibacterium acnes is one of the commonest microorganisms causing periprosthetic joint infection in shoulder arthroplasties. it is difficult to detect this slow growing microorganism. this paper gives an overview of the different diagnostic methods. a combination of unspecific and specific tests (detection of microorganism and sensitivity to ... | 2017 | 28701012 |
| combined photodynamic and antibiotic therapy for skin disorder via lipase-sensitive liposomes with enhanced antimicrobial performance. | a lipase-sensitive singlet oxygen-producible and erythromycin-loaded liposome (lsspl) was developed for combination antibacterial therapy for skin disorder. the lsspl was synthesized by coating pullulan-pheophorbide a (pu-pheo a) conjugates onto erythromycin-loaded liposomes composed of 1,2-dipalmitoyl-sn-phosphatidylcholine (dppc) and cholesterol. lipase activity was chosen as the environmental-stimulus for the controlled release of erythromycin and pheo a from lsspl because skin inflammation-i ... | 2017 | 28697465 |
| association between post-craniotomy propionibacterium acnes infection and dural implants: a case-control study. | in 2011, 15 deep-seated propionibacterium acnes infections were identified in patients following craniotomies in a hospital in the uk. | 2017 | 28694086 |
| propionibacterium acnes host inflammatory response during periprosthetic infection is joint specific. | propionibacterium acnes (p. acnes) has become increasingly recognized as a cause of periprosthetic joint infection (pji). | 2017 | 28690466 |
| immunohistochemical identification of propionibacterium acnes in granuloma and inflammatory cells of myocardial tissues obtained from cardiac sarcoidosis patients. | although rare, cardiac sarcoidosis (cs) is potentially fatal. early diagnosis and intervention are essential, but histopathologic diagnosis is limited. we aimed to detect propionibacterium acnes, a commonly implicated etiologic agent of sarcoidosis, in myocardial tissues obtained from cs patients. | 2017 | 28686683 |
| a case of bilateral hilar and mediastinal lymphadenopathy developing during treatment for mycobacterium avium complex. | we report a rare case of an immunocompetent patient with mycobacterium avium complex (mac) disease in which bilateral hilar lymphadenopathy developed during anti-mac treatment. this case indicates that propionibacterium acnes would be present and might be a cause of sarcoidosis even in patients with mac. | 2017 | 28680616 |
| combination of benzoyl peroxide 5% gel with liquid cleanser and moisturizer spf 30 in acne treatment results in high levels of subject satisfaction, good adherence and favorable tolerability. | skin care products (cleansers and moisturizers) to complement benzoyl peroxide (bpo) in the treatment of acne may improve treatment tolerability and adherence. | 2017 | 28678647 |
| acne. | acne is a chronic disease with a high prevalence among adolescents. key pathogenetic factors (and their clinical correlates) are increased sebum production (seborrhea), follicular hyperkeratosis (comedones), and perifollicular inflammation (papules and pustules). the disease is modulated by a variety of endogenous (androgens, igf-1, neuroendocrine factors) and exogenous (propionibacterium acnes, diet, friction, ingredients of medical or cosmetic topical products) triggers. acne is associated wit ... | 2017 | 28677199 |
| akne. | akne ist eine chronische erkrankung mit hoher prävalenz unter jugendlichen. pathogenetische hauptfaktoren (und ihre klinischen korrelate) sind gesteigerte talgproduktion (seborrhoe), follikuläre hyperkeratose (komedonen) und perifollikuläre entzündungsvorgänge (papulopusteln). die krankheit wird von endogenen (androgene, igf-1, neuroendokrine faktoren) und exogenen (propionibacterium acnes, diät, mechanische irritation, inhaltsstoffe medizinischer oder kosmetischer externa) einflüssen moduliert. ... | 2017 | 28677193 |