Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| the use of pcr/electrospray ionization-time-of-flight-mass spectrometry (pcr/esi-tof-ms) to detect bacterial and fungal colonization in healthy military service members. | the role of microbial colonization in disease is complex. novel molecular tools to detect colonization offer theoretical improvements over traditional methods. we evaluated pcr/electrospray ionization-time-of-flight-mass spectrometry (pcr/esi-tof-ms) as a screening tool to study colonization of healthy military service members. | 2016 | 27448413 |
| the novel aminomethylcycline omadacycline has high specificity for the primary tetracycline-binding site on the bacterial ribosome. | omadacycline is an aminomethylcycline antibiotic with potent activity against many gram-positive and gram-negative pathogens, including strains carrying the major efflux and ribosome protection resistance determinants. this makes it a promising candidate for therapy of severe infectious diseases. omadacycline inhibits bacterial protein biosynthesis and competes with tetracycline for binding to the ribosome. its interactions with the 70s ribosome were, therefore, analyzed in great detail and comp ... | 2016 | 27669321 |
| is there any association between sarcoidosis and infectious agents?: a systematic review and meta-analysis. | during the last few years, investigators have debated the role that infectious agents may have in sarcoidosis pathogenesis. with the emergence of new molecular biology techniques, several studies have been conducted; therefore, we performed a meta-analysis in order to better explain this possible association. | 2016 | 27894280 |
| multiplex antibody detection for noninvasive genus-level diagnosis of prosthetic joint infection. | we developed and evaluated a multiplex antibody detection-based immunoassay for the diagnosis of prosthetic joint infections (pjis). sixteen protein antigens from three staphylococcusspecies (staphylococcus aureus,staphylococcus epidermidis, and staphylococcus lugdunensis) (8 antigens),streptococcus agalactiae(4 antigens), and propionibacterium acnes(4 antigens) were selected by comparative immune proteomics using serum samples from pji cases versus controls. a bead-based multiplex immunoassay t ... | 2016 | 26865683 |
| urban transit system microbial communities differ by surface type and interaction with humans and the environment. | public transit systems are ideal for studying the urban microbiome and interindividual community transfer. in this study, we used 16s amplicon and shotgun metagenomic sequencing to profile microbial communities on multiple transit surfaces across train lines and stations in the boston metropolitan transit system. the greatest determinant of microbial community structure was the transit surface type. in contrast, little variation was observed between geographically distinct train lines and statio ... | 2016 | 27822528 |
| genome stability of propionibacterium acnes: a comprehensive study of indels and homopolymeric tracts. | we present a species-wide comparative analysis of 90 genomes of propionibacterium acnes that represent the known diversity of the species. our results are augmented by six high-quality genomes and a manual investigation of all gene-sized indels found in the strains. overall, the order of genes is conserved throughout the species. a public sybil database for easy comparative analysis of the 90 genomes was established. the analysis of indels revealed a total of 66 loci of non-core genes that corre ... | 2016 | 26857276 |
| lung microbiome analysis in steroid-naїve asthma patients by using whole sputum. | although recent metagenomic approaches have characterized the distinguished microbial compositions in airways of asthmatics, these results did not reach a consensus due to the small sample size, non-standardization of specimens and medication status. we conducted a metagenomics approach by using terminal restriction fragment length polymorphism (t-rflp) analysis of the induced whole sputum representing both the cellular and fluid phases in a relative large number of steroid naïve asthmatics. | 2016 | 27433177 |
| propionic acid produced by propionibacterium acnes strains contri-butes to their pathogenicity. | propionibacterium acnes is an important member of the skin microbiome. the bacterium can initiate signalling events and changes in cellular properties in keratinocytes. the aim of this study was to analyse the effect of the bacterium on an immortalized human keratinocyte cell line. the results show that various p. acnes strains affect the cell-growth properties of these cells differentially, inducing cytotoxicity in a strain-specific and dose-dependent manner. we propose that bacterially secrete ... | 2016 | 26039371 |
| sunscreen remanence on the skin: a noninvasive real time in vivo spectral analysis assessing the quenching of specular ultraviolet a light reflectance. | under specific light illumination, particularly ultraviolet radiation (uvr), the skin produces both specular light reflectance and, possibly, specific fluorescent emission. a quenching effect of fluorescence is observed following the application of sunscreens active against uva radiations. | 2016 | 26260120 |
| multicenter cross-sectional observational study of antibiotic resistance and the genotypes of propionibacterium acnes isolated from chinese patients with acne vulgaris. | antibiotics are widely applied in management of acne vulgaris, which raises the issue of antibiotic resistance. due to improper application and supervision of antibiotics, antibiotic resistance has become a serious problem in china. so, the efficacy of antimicrobial therapy in acne is unclear without an objective monitor of antibiotic resistance of propionibacterium acnes. this cross-sectional, multicenter observational study is aimed at understanding the status of antibiotic resistance in p. ac ... | 2016 | 26508505 |
| [low grade endophthalmitis caused by p. acnes : case report]. | low grade endophthalmitis is usually a chronic indolent inflammation that may be misdiagnosed as noninfectious uveitis. therefore, this form of endophthalmitis is often unsuccessfully treated with corticosteroids. we describe the case of a patient with low grade endophthalmitis caused by propionibacterium acnes after cataract surgery. this case report presents the difficulties in establishing the diagnosis of this form of endophthalmitis as well as the benefits of a combined operative therapy wi ... | 2016 | 26531293 |
| investigation of antibacterial activity of aspidin bb against propionibacterium acnes. | in the present study, antibacterial activity of four kinds of phloroglucinol derivatives extracted from dryopteris fragrans (l.) schott against s. aureus, s. epidermidis and p. acnes has been tested. aspidin bb exerted the strongest antibacterial activity with minimal inhibition concentration (mic) values ranging from 7.81 to 15.63 μg/ml. the time-kill assay indicated that aspidin bb could kill p. acnes completely at 2 mic (mbc) within 4 h. by using afm, we demonstrated extensive cell surface al ... | 2016 | 26596576 |
| effect of surgical delay on bacterial colonization in proximal humeral fractures. | postoperative infection is a severe complication after proximal humeral fracture surgical treatment. the aim of this study was to determine if the surgical delay could modify the number and type of bacteria on the surgical site. a two stages study was set up. in the first stage the effect of delay was simulated in 20 patients affected by proximal humeral fracture treated conservatively. in a second stage, the effect of delay was measured in 20 patients that underwent surgery. in stage 1, three s ... | 2016 | 26580139 |
| association between lumbar disc degeneration and propionibacterium acnes infection: clinical research and preliminary exploration of animal experiment. | clinical research and animal experiment. | 2016 | 26656049 |
| microbial colonization of normal skin: direct visualization of 194 skin biopsies. | recent genetic studies have suggested the presence of numerous microbial species on and in the skin. we characterised microbial colonization of a large collection of skin biopsies from 194 healthy subjects by fluorescence assay. forty per cent of all biopsies did not show any evidence for microbial colonization. propionibacterium acnes was the sole predominant bacterial species in both sebaceous and non-sebaceous areas. non- p. acnes species were present in approximately 30% of all colonized sam ... | 2016 | 26655456 |
| microorganisms inhabiting follicular contents of facial acne are not only propionibacterium but also malassezia spp. | to clarify the relationship between major cutaneous microorganisms (propionibacterium, staphylococcus and malassezia spp.) and acne vulgaris (acne), we examined the microbiota quantitatively in the follicular contents of inflammatory acne and on the facial skin of patients with acne. fifteen japanese untreated acne outpatients were studied. the follicular contents from inflammatory acne lesions of the face were collected using a comedo extractor. the skin surface samples were obtained by the swa ... | 2016 | 26705192 |
| propionibacterium acnes in primary shoulder arthroplasty: rates of colonization, patient risk factors, and efficacy of perioperative prophylaxis. | recent literature has shown that propionibacterium acnes can be cultured from superficial and deep layers of the shoulder. our aims were to assess the rate of p. acnes colonization in patients undergoing primary shoulder arthroplasty, to identify patient-related risk factors, and to evaluate the efficacy of our perioperative antisepsis protocol. | 2016 | 26704361 |
| compressive spinal epidural mass caused by propionibacterium acnes. | propionibacterium acnes is a gram-positive and facultative anaerobe bacillus that is found within sebaceous follicles of the human skin and recognized as a cause of infections after spinal surgery. to our knowledge, there has been no previously reported case of symptomatic compressive chronic inflammatory epidural mass caused by p. acnes in a patient with no prior spinal procedures. | 2016 | 26721733 |
| deciphering the effect of novel bacterial exopolysaccharide-based nanoparticle cream against propionibacterium acnes. | acne vulgaris (acne) is a chronic inflammatory disease prevalent among adolescents and adults, with significant psychological effects. the aetiology of acne is multifactorial. several pathophysiological associations have been identified in which propionibacterium acnes plays a major role. this bacteria primarily affects areas containing oil glands including the face, back and trunk, where it causes the formation of seborrhoea and inflammatory lesions. the treatment methods currently in place hav ... | 2016 | 28330105 |
| staphylococcus aureus carriage rates and antibiotic resistance patterns in patients with acne vulgaris. | overuse of antibiotics has led to the development of antibiotic-resistant strains of staphylococcus aureus, which are occurring more frequently within the community. | 2016 | 26777099 |
| propionibacterium acnes in shoulder surgery: is loss of hair protective for infection? | propionibacterium acnes (p acnes) has been linked to chronic infections in shoulder surgery. it was recently observed during first-time shoulder surgery in healthy patients at a rate between 36% and 56%. male gender and the anterolateral approach were reported risk factors. because the skin biology greatly differs, we aimed to correlate skin complaints with p acnes-positive intraoperative cultures from different tissue layer samples in patients undergoing shoulder surgery for the first time. | 2016 | 26763856 |
| rapid diagnosis of propionibacterium acnes infection in patient with hyperpyrexia after hematopoietic stem cell transplantation by next-generation sequencing: a case report. | the rapid determination of pathogenic agent is very important to clinician for guiding their clinical medication. however, current diagnostic methods are of limitation in many aspects, such as detecting range, time-consuming, specificity and sensitivity. in this report, we apply our new-developing pathogen detection method to clarify that propionibacterium acnes is the causative agent of a two-year-old boy with juvenile myelomonocytic leukemia presenting clinical symptoms including serious rash ... | 2016 | 26743541 |
| staphylococcal lta-induced mir-143 inhibits propionibacterium acnes-mediated inflammatory response in skin. | staphylococcus epidermidis (s. epidermidis) plays a critical role in modulating cutaneous inflammatory responses in skin. although s. epidermidis has been shown to co-colonize with propionibacterium acnes (p. acnes) in acne lesions, it is unclear whether s. epidermidis is involved in the regulation of p. acnes-induced inflammatory responses. in this study, we demonstrated that s. epidermidis inhibited p. acnes-induced inflammation in skin. p. acnes induced the expression of interleukin-6 and tum ... | 2016 | 26739093 |
| [bacterial resistance in acne? a meta-analysis of the controversy]. | acne is one of the dermatological pathologies with the highest incidence around the world. it is a multifactorial disease and its treatment can be complex. propionibacterium acnes play a key role in the inflammation of this dermatosis. topical antibiotics, including mainly erythromycin and clindamycin, have been used, but there is controversy over their use due to the widely documented bacterial resistance. for this reason a meta-analysis of the publications over the past 10 years is presented i ... | 2016 | 26738649 |
| antimicrobial activities of ozenoxacin against isolates of propionibacteria and staphylococci from japanese patients with acne vulgaris. | ozenoxacin, a novel non-fluorinated topical quinolone, was assessed for in vitro antimicrobial activity against clinical isolates of propionibacteria and staphylococci according to the broth microdilution method recommended by the clinical and laboratory standards institute. the isolates used in this study were collected from japanese patients with acne vulgaris during a period from 2012 to 2013. the mic90s of ozenoxacin against propionibacterium acnes (n=266), propionibacterium granulosum (n=10 ... | 2016 | 27305898 |
| staphylococcus epidermidis sets things right again. | commensal cutaneous bacteria are believed to play a role in skin homeostasis, possibly by counteracting the effects of pathogenic inflammation. in this issue, xia et al. show that staphylococcus epidermidis is involved in the regulation of propionibacterium acnes-induced inflammation. staphylococcal lipoteichoic acid induces mir-143, which in turn inhibits toll-like receptor 2 mrna to decrease toll-like receptor 2 protein and consequently suppresses p. acnes-induced proinflammatory cytokines. | 2016 | 26902125 |
| guidelines of care for the management of acne vulgaris. | acne is one of the most common disorders treated by dermatologists and other health care providers. while it most often affects adolescents, it is not uncommon in adults and can also be seen in children. this evidence-based guideline addresses important clinical questions that arise in its management. issues from grading of acne to the topical and systemic management of the disease are reviewed. suggestions on use are provided based on available evidence. | 2016 | 26897386 |
| high-throughput sequencing of cerebrospinal fluid for diagnosis of chronic propionibacterium acnes meningitis in an allogeneic stem cell transplant recipient. | a 40-year-old man with chronic myelogenous leukemia presented multiple times over a period of 3 years with episodes of confusion, wide-based gait and falls because of recurrent hydrocephalus despite repeated therapeutic lumbar punctures. these problems occurred in the context of persistent cerebrospinal fluid (csf) pleocytosis and leptomeningeal enhancement. extensive diagnostic workups and therapeutic trials had failed to identify a clinically plausible cause or produce any significant improvem ... | 2016 | 26895706 |
| glycerol monolaurate inhibits lipase production by clinical ocular isolates without affecting bacterial cell viability. | we sought to determine the relative lipase production of a range of ocular bacterial isolates and to assess the efficacy of glycerol monolaurate (gml) in inhibiting this lipase production in high lipase-producing bacteria without affecting bacterial cell growth. | 2016 | 26873514 |
| do sublaminar polyester bands affect the outcomes of postoperative infections after adolescent idiopathic scoliosis surgery? | the incidence of surgical site infections (ssi) after adolescent idiopathic scoliosis (ais) surgery ranges from 0.5% to 7%. there is currently a regain of interest in hybrid constructs, combining lumbar pedicle screws and thoracic sublaminar bands, but some authors have raised concerns about the risk of ssi and the difficulty of bacterial eradication. the goal of this study was therefore to assess the outcomes of ssi after ais surgery using sublaminar bands. | 2016 | 26866646 |
| systematic review of antibiotic resistance in acne: an increasing topical and oral threat. | topical and oral antibiotics are routinely used to treat acne. however, antibiotic resistance is increasing, with many countries reporting that more than 50% of propionibacterium acnes strains are resistant to topical macrolides, making them less effective. we reviewed the current scientific literature to enable proposal of recommendations for antibiotic use in acne treatment. references were identified through pubmed searches for articles published from january, 1954, to march 7, 2015, using fo ... | 2016 | 26852728 |
| effects of magnesium ascorbyl phosphate on the expression of inflammatory biomarkers after treatment of cultured sebocytes with propionibacterium acnes or ultraviolet b radiation. | 2016 | 26848238 | |
| wide-spectrum activity of a silver-impregnated fabric. | fabrics, such as clothing, drapes, pillowcases, and bedsheets are potential sources of pathogenic bacteria and viruses. we found fabrics (ie, professional clothing, pillowcases, and lab coats) treated with a silver-impregnated material to be effective in significantly reducing a wide spectrum of ordinary and drug-resistant microorganisms, including salmonella, methicillin-resistant staphylococcus aureus, propionibacterium acnes, trichphyton mentagrophytes, and norovirus. fabrics impregnated with ... | 2016 | 26827093 |
| overview: the role of propionibacterium acnes in nonpyogenic intervertebral discs. | propionibacterium acnes (p. acnes), an important opportunistic anaerobic gram-positive bacterium, causes bone and joint infections, discitis and spondylodiscitis. accumulated evidence suggested that this microbe can colonise inside intervertebral discs without causing symptoms of discitis. epidemiological investigation shows that the prevalence ranges from 13 % to 44 %. furthermore, colonisation by p. acnes inside nonpyogenic intervertebral discs is thought to be one pathogen causing sciatica, m ... | 2016 | 26820744 |
| propionibacterium acnes: disease-causing agent or common contaminant? detection in diverse patient samples by next-generation sequencing. | propionibacterium acnesis the most abundant bacterium on human skin, particularly in sebaceous areas.p. acnesis suggested to be an opportunistic pathogen involved in the development of diverse medical conditions but is also a proven contaminant of human clinical samples and surgical wounds. its significance as a pathogen is consequently a matter of debate. in the present study, we investigated the presence ofp. acnesdna in 250 next-generation sequencing data sets generated from 180 samples of 20 ... | 2016 | 26818667 |
| in vitro antimicrobial activity of benzoyl peroxide against propionibacterium acnes assessed by a novel susceptibility testing method. | benzoyl peroxide (bpo), a therapeutic agent for acne vulgaris, was assessed for in vitro antimicrobial activity against propionibacterium acnes using a novel broth microdilution testing that improved bpo solubility. we searched for a suitable culture medium to measure the minimum inhibitory concentration (mic) of bpo against p. acnes and finally found the gifu anaerobic medium (gam) broth supplemented with 0.1(v/v)% glycerol and 2(v/v)% tween 80, in which bpo dissolved up to 1250 μg/ml and p. ac ... | 2016 | 26806150 |
| follicular fluorescence quantity to characterize acne severity: a validation study. | porphyrins are native fluorophores in the follicle openings, visible under ultraviolet-a light. acne severity might be associated with increased propionibacterium acnes colonization and porphyrin production. aim of this study was to investigate whether the parameter fluorescence quantity can be used to measure acne severity. | 2016 | 26804729 |
| antimicrobial activities of ethanol and butanol fractions of white rose petal extract. | white rose (rosa hybrida) petals were extracted with ethanol (etoh) or butanol (buoh), and tested for their antimicrobial activities against two species of gram-positive bacteria, six species of gram-negative bacteria, and two species of fungi. on in vitro antimicrobial assays, helicobacter pylori and propionibacterium acnes were highly susceptible to white rose petal extract (wrpe)-etoh and wrpe-buoh, leading to minimal inhibitory concentrations of 100 and 10 μg/ml for h. pylori and 400 and 40 ... | 2016 | 26802535 |
| bilateral sequential propionibacterium acnes exogenous endophthalmitis. | a 68-year-old man underwent uncomplicated sequential cataract extractions performed more than a year apart. he presented 6 months after the second surgery with persistent intraocular inflammation in both eyes. cultures from both eyes grew propionibacterium acnes and he responded well to treatment. suspicion for delayed-onset post-operative endophthalmitis must remain high in uveitis cases that fail to resolve with anti-inflammatory treatments. the authors believe this is the first reported case ... | 2016 | 27220771 |
| clinical features of infectious keratitis caused by propionibacterium acnes. | propionibacterium acnes is a commensal bacteria whose pathogenicity in infectious keratitis is unclear. in this study, we report infectious keratitis cultured with p. acnes and evaluate its clinical characteristics. | 2016 | 27203796 |
| pulmonary fibrosis in a mouse model of sarcoid granulomatosis induced by booster challenge with propionibacterium acnes. | pulmonary fibrosis (pf) associated with chronic sarcoidosis remains poorly understood, and no experimental model is currently available for this condition. previous studies have shown that propionibacterium acnes (pa) was associated with sarcoidosis and induced granuloma formation in mice. here, we investigated whether repeated challenge with pa induces persistent inflammation leading to sarcoidosis followed by pf in mice. specifically, c57bl/6 mice were inoculated intraperitoneally and subjecte ... | 2016 | 27203210 |
| first cultivation of health-associated tannerella sp. hot-286 (bu063). | despite significant advances in recent years in culture-independent molecular microbiology methods, the detailed study of individual bacterial species still relies on having pure cultures in the laboratory. yet, more than a third of the approximately 700 bacterial taxa found in the human oral cavity are as yet uncultivated in vitro. one such taxon, tannerella sp. hot-286 (phylotype bu063), is the focus of much interest since it is associated with periodontal health, while tannerella forsythia, i ... | 2016 | 27193146 |
| inhibition of propionibacterium acnes associated biofilm formation by decanediol. | 2016 | 27188522 | |
| comparison effect of azithromycin gel 2% with clindamycin gel 1% in patients with acne. | acne vulgaris is the most common skin disease. local and systemic antimicrobial drugs are used for its treatment. but increasing resistance of propionibacterium acnes to antibiotics has been reported. | 2016 | 27169103 |
| nasal and conjunctival screening prior to refractive surgery: an observational and cross-sectional study. | to investigate bacterial flora of clinically healthy conjunctiva and nasal cavity among patients prior to refractive surgery, as well as the characteristics of patients with methicillin-resistant staphylococcus aureus (mrsa) colonisation. | 2016 | 27160843 |
| osteomyelitis of the humerus caused by propionibacterium acnes. | propionibacterium acnes is a fastidious slow-growing anaerobic gram-positive bacillus best known for causing acne. however, it only occasionally has been isolated from invasive infections. in that setting, slow growth and low virulence may lead to indolent presentations and diagnostic delays as illustrated by the following case. | 2016 | 27159477 |
| influence of a polymerizable eugenol derivative on the antibacterial activity and wettability of a resin composite for intracanal post cementation and core build-up restoration. | eugenol has been used in dentistry due to its ability to inhibit the growth of a range of microorganisms, including facultative anaerobes commonly isolated from infected root canals. the aim of this study was to evaluate the antibacterial activity of the experimental composites containing eugenyl methacrylate monomer (egma), a polymeric derivative of eugenol, against a range of oral bacteria, commonly associated with failure of coronal and endodontic restorations. in vitro composite behavior and ... | 2016 | 27130610 |
| quantification of the antibody response to propionibacterium acnes in a patient with prosthetic valve endocarditis: - a case report. | the isolation of propionibacterium acnes in blood cultures is often considered a contaminant. on rare occasions, p. acnes can cause severe infections, including endocarditis and intravascular prosthesis-associated infections. to evaluate the discrimination between a contaminant and a clinically relevant infection we used an ouchterlony test system to quantify the antibody response to p. acnes in a patient with a proven p. acnes endocarditis. | 2016 | 27126586 |
| absence or low density of propionibacterium acnes in comedonal lesions of acne patients? a surface to inside study of skin fluorescence. | 2016 | 27125260 | |
| microbiota of an italian grana-like cheese during manufacture and ripening, unraveled by 16s rrna-based approaches. | the microbial ecology of cheese involves a rich and complex interaction between starter lactic acid bacteria and nonstarter lactic acid bacteria (nslab), mainly originating from raw milk and/or from the environment, that can contribute to the final characteristics of cheese. the aim of the present research was the exploration of the active microbiota by rna-based approaches during the manufacturing and ripening of a grana-like cheese. reverse transcriptase pcr (rt-pcr)-denaturing gradient gel el ... | 2016 | 27107125 |
| propionibacterium acnes infected intervertebral discs cause vertebral bone marrow lesions consistent with modic changes. | modic type i change (mc1) are vertebral bone marrow lesions adjacent to degenerated discs that are specific for discogenic low back pain. the etiopathogenesis is unknown, but occult discitis, in particular with propionibacteria acnes (p. acnes), has been suggested as a possible etiology. if true, antibiotic therapy should be considered for patients with mc1. however, this hypothesis is controversial. while some studies report up to 40% infection rate in herniated discs, others fail to detect inf ... | 2016 | 27101067 |
| a silent ghost in the right atrium. | 2016 | 27082775 | |
| efficacy of red or infrared light-emitting diodes in a mouse model of propionibacterium acnes-induced inflammation. | laser/light-based devices may provide an alternative to conventional acne therapeutics in some patients with nonresponsive acne. | 2016 | 27081265 |
| pulmonary mucosa-associated lymphoid tissue lymphoma associated with pulmonary sarcoidosis: a case report and literature review. | differentiating low-grade lymphoma from preexisting sarcoidosis is difficult because of their pathological similarity. this article describes a case of pulmonary mucosa-associated lymphoid tissue lymphoma associated with pulmonary sarcoidosis. the patient, a 45-year-old japanese man, presented with a 10-year history of pulmonary sarcoidosis and 5-year history of ocular sarcoidosis with histologic findings. because only the right s3 lung nodule had gradually enlarged, partial resection was perfor ... | 2016 | 27067783 |
| prosthetic valve endocarditis due to propionibacterium acnes. | to study the characteristics of patients with propionibacterium acnes prosthetic valve endocarditis (pve) who required surgery. | 2016 | 27052748 |
| which is the best treatment for prosthetic joint infections due to propionibacterium acnes: need for further biofilm in vitro and experimental foreign-body in vivo studies? | 2016 | 27045190 | |
| zolav(®) (a p-carboethoxy-tristyrylbenzene derivative) [corrected]: a new antibiotic for the treatment of acne. | acne is a prominent skin condition affecting >80% of teenagers and young adults and ~650 million people globally. isotretinoin, a vitamin a derivative, is currently the standard of care for treatment. however, it has a well-established teratogenic activity, a reason for the development of novel and low-risk treatment options for acne. | 2016 | 27042015 |
| the challenge of propionibacterium acnes and revision shoulder arthroplasty: a review of current diagnostic options. | propionibacterium acnes is the most common cause of infection after shoulder arthroplasty. whereas there are several methods that can aid in the diagnosis of p. acnes infection, there is not a single "gold standard" because of the difficulties inherent in identifying this bacterium. we present an evidence-based discussion of the demographic, clinical, and radiographic predictors of p. acnes infection and review the current options for diagnosis. | 2016 | 27038565 |
| clinical analysis of propionibacterium acnes infection after total knee arthroplasty. | propionibacterium acnes is a common cause of upper extremity arthroplasty infection and usually presents in an indolent subacute fashion. it is not well described how total knee arthroplasty (tka) patients infected with p acnes present. | 2016 | 27036925 |
| microbiologic profile of infections in presumed aseptic revision spine surgery. | intra-operative cultures may be obtained in revision spine surgery despite the absence of pre-operative clinical markers of infection. the microbiologic profile of culture positive cases in which there is no clear evidence of infection preoperatively has not been described. the aim of this investigation is to report on the microbiologic profile of unexpected culture positive revision spine surgery cases. | 2016 | 27026016 |
| propionibacterium prosthetic joint infection: experience from a retrospective database analysis. | with improved diagnostic methods and longer prosthesis indwelling time, the frequency of diagnosed propionibacterium prosthetic joint infections (pji) is increasing. data on clinical, microbiological, radiological and surgical treatment are limited, and importance of this organism in pji is probably underestimated. | 2016 | 27017334 |
| physical modalities (devices) in the management of acne. | treatment options for acne vulgaris are enhanced by laser and light therapy. both visible and laser light are effective treatments for acne. visible light and many lasers target propionibacterium acnes porphyrins while others act as anti-inflammatory mediators or reduce sebaceous gland activity. compared with topical and systemic therapies, laser and light therapies have few if any side effects and appear to be safe during pregnancy. if patients prefer at home light treatments, several devices a ... | 2016 | 27015782 |
| the clinical relevance of antibiotic resistance: thirteen principles that every dermatologist needs to consider when prescribing antibiotic therapy. | antibiotics are commonly used by dermatologists in clinical practice, primarily because of the overall track record of favorable efficacy and safety with the most commonly used agents. during the past decade, increased attention has been given to the problems associated with antibiotic resistance. this article summarizes important principles gleaned from the continued efforts of the scientific panel on antibiotic use in dermatology; other groups working diligently in this area, such as the cente ... | 2016 | 27015776 |
| the relationship of proper skin cleansing to pathophysiology, clinical benefits, and the concomitant use of prescription topical therapies in patients with acne vulgaris. | patients often perceive the cause of their acne to be related to a lack of proper cleansing, therefore many patients attempt to treat their acne either alone or with prescription therapy by frequent aggressive cleansing with harsh cleansing agents. altered epidermal barrier function, inflammation, and propionibacterium acnes are related to acne vulgaris (av) pathophysiology; proper cleansing can favorably modulate the development of av. the available clinical studies support gentle cleansing in ... | 2016 | 27015773 |
| outcomes in the treatment of periprosthetic joint infection after shoulder arthroplasty: a systematic review. | although many case series have been published on the treatment of shoulder periprosthetic joint infection (pji), few provide direct comparison of outcomes. this systematic review synthesizes the available english literature on shoulder pji to quantify treatment effectiveness. | 2016 | 27012542 |
| propionibacterium acnes brain abscess in an immunocompetent man in the absence of prior neurosurgery. | propionibacterium acnes is a rare, but established, cause of intracranial abscesses. we describe a case of p. acnes brain abscess in an immunocompetent man without prior neurosurgery. a 49-year old man with mild psoriasis presented with a two-week history of gait changes, generalized weakness and a two-day history of headaches, aphasia and confusion. imaging revealed a left thalamic mass and surgical biopsy suggested a pyogenic abscess. cultures of biopsy samples of the abscess grew p. acnes alo ... | 2016 | 26999913 |
| [bacterial vaginosis: efficacy of a local treatment with a gel containing a fraction derived from propinibacterium acnes]. | bacterial vaginosis (bv) is favored by a decreased activity of vaginal immune system. the fraction derived from propionibacterium acnes is known to activate the immune system and is used parenterally to treat respiratory and urinary infections. the employ of a fraction derived from propionibacterium acnes locally, in the context of the vaginal immune system, is made possible by a vaginal gel in which this fraction is associated with hyaluronic acid, well-known for its moisturizing activity, and ... | 2016 | 26990097 |
| an in vitro model for bacterial growth on human stratum corneum. | the diversity and dynamics of the skin microbiome in health and disease have been studied recently, but adequate model systems to study skin microbiotas in vitro are largely lacking. we developed an in vitro system that mimics human stratum corneum, using human callus as substrate and nutrient source for bacterial growth. the growth of several commensal and pathogenic bacterial strains was measured for up to one week by counting colony-forming units or by quantitative pcr with strain-specific pr ... | 2016 | 26976779 |
| discovery of a novel seminal fluid microbiome and influence of estrogen receptor alpha genetic status. | bacteria harbored in the male reproductive system may influence reproductive function and health of the male and result in developmental origins of adult health and disease (dohad) effects in his offspring. such effects could be due to the seminal fluid, which is slightly basic and enriched with carbohydrates; thereby, creating an ideal habitat for microbes or a potential seminal fluid microbiome (sfm). using wild-type (wt) and estrogen receptor-alpha (esr1) knockout (ko) male mice, we describe ... | 2016 | 26971397 |
| a myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of propionibacterium acnes biofilms to antibiotics used in acne vulgaris. | recent works present evidence of propionibacterium acnes growing as a biofilm in cutaneous follicles. this formation of clusters is now considered as an explanation for the in vivo resistance of p. acnes to the main antimicrobials prescribed in acne vulgaris. | 2016 | 26969384 |
| the formulation of bacteriophage in a semi solid preparation for control of propionibacterium acnes growth. | to isolate and characterise phage which could lyse p. acnes and to formulate the phage into a delivery form for potential application in topical treatment of acne infection. | 2016 | 26964063 |
| dilemmas surrounding the diagnosis of deep brain stimulation electrode infection without associated wound complications: a series of two cases. | when wounds are benign, diagnosis of deep brain stimulation (dbs) electrode infection and associated intraparenchymal infection can be challenging. only a couple, such cases exist in literature. since infections of the central nervous system can be life-threatening, prompt diagnosis is necessary to prevent neurological injury. employed within the appropriate context, magnetic resonance imaging (mri) of the brain, as well as laboratory data and clinical presentation, may help guide diagnosis. | 2016 | 26958428 |
| draft genome sequence of highly rifampin-resistant propionibacterium namnetense nts 31307302t isolated from a patient with a bone infection. | propionibacterium namnetense was recently described as a potential bone pathogen, which is closely related to propionibacterium acnes, a skin commensal microorganism. here, we report the draft genome sequence of the highly rifampin-resistant strain nts 31307302(t) isolated from a patient with a tibia infection. | 2016 | 27516511 |
| evaluation of the antioxidative, antibacterial, and anti-inflammatory effects of the aloe fermentation supernatant containing lactobacillus plantarum hm218749.1. | little work is done to develop aloe vera (av) using probiotics. to explore the potential benefits, the antioxidant effects and the antibacterial effects on foodborne pathogens of aloe fermentation supernatant were evaluated in vitro. our results indicated that the aloe fermentation supernatant fermented by lactobacillus plantarum hm218749.1 had very strong scavenging capacities of the dpph (86%), o2 (•-) (85%), (•)oh (76%), and fe(2+) chelation (82%) and reducing powers (242.5 mg/l), and the inh ... | 2016 | 27493450 |
| analysis of postoperative thoracolumbar spine infections in a prospective randomized controlled trial using the centers for disease control surgical site infection criteria. | wound infections following spinal surgery place a high toll on both the patient and the healthcare system. although several large series studies have examined the incidence and distribution of spinal wound infection, the applicability of these studies varies greatly since nearly every study is either retrospective and/or lacks standard inclusion criteria for defining surgical site infection. to address this void, we present results from prospectively gathered thoracolumbar spine surgery data for ... | 2016 | 27441172 |
| heterogeneity and antibiotic resistance in propionibacterium acnes isolates and its therapeutic implications: blurring the lines between commensal and pathogenic phylotypes. | acne vulgaris is a multifactorial skin disease associated with the colonization of propionibacterium acnes. antibiotics are a mainstay of treatment for acne, yet the emergence of resistance against the currently approved antibiotics is a serious concern. in this case report, a slow responder had multiple propionibacterium acnes isolates with varied levels of sensitivity to the conventional antibiotics. the bacterial isolates obtained from acne samples collected from the patient were analyzed for ... | 2016 | 27424878 |
| drug eruption secondary to vancomycin-laden spacer in the shoulder: a case report. | 2016 | 27422463 | |
| effects of 5-aminolevulinic acid photodynamic therapy on tlrs in acne lesions and keratinocytes co-cultured with p. acnes. | to investigate the effect of 5-aminolevulinic acid photodynamic therapy (ala-pdt) on the expression of toll like receptors (tlrs) in human keratinocytes and its role in acne treatment. | 2016 | 27421917 |
| recent progress in the research about propionibacterium acnes strain diversity and acne: pathogen or bystander? | recent progress has steadily reported the existence of the diverse strains of propionibacterium acnes, and these studies have contributed to the elucidation of their contradictory roles between normal commensals and pathogens. in this review, the authors aimed to provide an update on the recent understanding of research about p. acnes strain diversity and acne, analyzing the potential implications for clinical applications. before the era of genomic research, p. acnes was known to be distinguish ... | 2016 | 27421121 |
| antibiotic-resistant acne: getting under the skin. | propionibacterium acnes is a key pathogenic factor in the development of acne. antibiotics are the first choice of treatment for mild-to-moderate, mixed, papular/pustular, and moderate nodular acne, and an alternative choice in severe, nodular/conglobate acne. the emergence of resistance to the currently available antibiotics poses a serious set-back to this algorithm, and the reduced arsenal can diminish efficacy of treatment. this emerging situation should catalyze innovations in dermatology; ... | 2016 | 27416310 |
| topical and oral antibiotics for acne vulgaris. | antibiotics, both oral and topical, have been an integral component of the management of acne vulgaris (av) for approximately 6 decades. originally thought to be effective for av due to their ability to inhibit proliferation of propionibacterium acnes, it is now believed that at least some antibiotics also exert anti-inflammatory effects that provide additional therapeutic benefit. to add, an increase in strains of p acnes and other exposed bacteria that are less sensitive to antibiotics used to ... | 2016 | 27416309 |
| glove contamination during endodontic treatment is one of the sources of nosocomial endodontic propionibacterium acnes infections. | the opportunistic propionibacterium acnes recovered frequently from failed endodontic treatments might be the result of nosocomial endodontic infections. the study was aimed to determine if gloves worn by dentists could be one of the sources of these nosocomial infections and to investigate the p. acnes phylotypes involved. | 2016 | 27395473 |
| thoracic aortic graft infections secondary to propionibacterium species: two cases and review of the literature. | aortic graft infections are a rare occurrence, most commonly secondary to gram-positive organisms (staphylococcus and streptococcus species). we present 2 cases of thoracic aortic graft infections secondary to anaerobic bacteria, propionibacterium species. the first case, a 40-year-old male, was found to have an anastomotic aneurysm at the distal anastomosis of a previous thoracoabdominal aneurysm repair. during the open repair of his anastomotic aneurysm, the original graft was not incorporated ... | 2016 | 27381316 |
| antimicrobial activity of sebocytes against propionibacterium acnes via toll-like receptor 2 and lysosomal pathway. | 2016 | 27375109 | |
| propionibacterium avidum as an etiological agent of prosthetic hip joint infection. | propionibacterium acnes is well-established as a possible etiologic agent of prosthetic joint infections (pjis). other propionibacterium spp. have occasionally been described as a cause of pjis, but this has not previously been the case for p. avidum despite its capacity to form biofilm. we describe two patients with prosthetic hip joint infections caused by p. avidum. both patients were primarily operated with an anteriorly curved skin incision close to the skin crease of the groin, and both we ... | 2016 | 27355425 |
| propionibacterium acnes infection associated with cancerous prostate hypertrophy. | 2016 | 27629109 | |
| evaluation of intraoperative glove change in prevention of postoperative cerebrospinal fluid shunt infections, and the predictors of shunt infection. | we have previously suggested that surgical gloves could be a possible means for transferring microorganisms from skin flora to shunt material during surgery. the objectives of this study were to examine (1) whether the rate of shunt infections was reduced after introducing intraoperative glove change before handling the shunt material; (2) clinical presentation of shunt infections, microbiological data, and treatment management; and (3) predictors of shunt infections. | 2016 | 27626705 |
| assessment of a new biological complex efficacy on dysseborrhea, inflammation, and propionibacterium acnes proliferation. | acne vulgaris is a common chronic inflammatory disease of the pilosebaceous unit triggered by propionibacterium acnes. a bakuchiol, ginkgo biloba extract, and mannitol (bgm) complex has been developed to provide patients with acne with a specific dermocosmetic to be used adjunctively with conventional treatments. | 2016 | 27621660 |
| delayed propionibacterium acnes surgical site infections occur only in the presence of an implant. | whether propionibacterium acnes (p. acnes) causes surgical-site infections (ssi) after orthopedic surgery is controversial. we previously reported that we frequently find p. acnes in intraoperative specimens, yet none of the patients have clinically apparent infections. here, we tracked p. acnes for 6 months in a mouse osteomyelitis model. we inoculated p. acnes with an implant into the mouse femur in the implant group; the control group was treated with the bacteria but no implant. we then obse ... | 2016 | 27615686 |
| erratum to: frequency and typing of propionibacterium acnes in prostate tissue obtained from men with and without prostate cancer. | [this corrects the article doi: 10.1186/s13027-016-0074-9.]. | 2016 | 27335583 |
| inhibitory effects of schisandra chinensis extract on acne-related inflammation and uvb-induced photoageing. | schisandra chinensis (turcz.) baill. (schisandraceae) fruit extract (sfe) has been reported to induce non-specific tissue protection against inflammation in vivo. however, the effects of sfe on propionibacterium acnes-stimulated acne and uvb-irradiated photoageing have yet to be investigated. | 2016 | 27328727 |
| ereply. towards better understanding and management of propionibacterium acnes in cases of prosthetic valve endocarditis. | 2016 | 27325659 | |
| ecomment. towards better understanding and management of propionibacterium acnes in cases of prosthetic valve endocarditis. | 2016 | 27325658 | |
| saddle nose with sarcoidosis: "a great imitator" of relapsing polychondritis. | sarcoidosis is a systemic granulomatous disease that can affect any organ including the nose. nasal crusting and congestion are common nasal symptoms of sarcoidosis, whereas cases of saddle-nose deformity are rarely reported. we describe here a case of sarcoidosis that presented with saddle nose resembling relapsing polychondritis. since sarcoidosis shares clinical features with relapsing polychondritis, the differential diagnosis of saddle nose can be challenging without a clear pathology. | 2016 | 27321667 |
| frequency and typing of propionibacterium acnes in prostate tissue obtained from men with and without prostate cancer. | prostate cancer is the most common cancer among men in western countries but the exact pathogenic mechanism of the disease is still largely unknown. an infectious etiology and infection-induced inflammation has been suggested to play a role in prostate carcinogenesis and propionibacterium acnes has been reported as the most prevalent microorganism in prostatic tissue. we investigated the frequency and types of p. acnes isolated from prostate tissue samples from men with prostate cancer and from ... | 2016 | 27284286 |
| endocarditis in patients with ascending aortic prosthetic graft: a case series from a national multicentre registry. | endocarditis in patients with ascending aortic prosthetic graft (aapg) is a life-threatening complication. the purpose of this study was to examine the clinical presentation and prognosis of patients with aapg endocarditis included in a large prospective infectious endocarditis multicentre study. | 2016 | 27283156 |
| synovitis, acne, pustulosis, hyperostosis, and osteitis (sapho) syndrome - a challenging diagnosis not to be missed. | sapho syndrome manifests as chronic inflammation of bones and joints, which may or may not be accompanied by skin changes. the term sapho is an acronym that stands for synovitis, acne, pustulosis (usually palmoplantar), hyperostosis and osteitis. the bones most commonly affected are those in the anterior chest wall (mainly the sternum, clavicles and sternocostoclavicular joints), the vertebrae and the sacroiliac joints, but peripheral and flat bones may also be involved, especially in children. ... | 2016 | 27263075 |
| propionibacterium namnetense sp. nov., isolated from a human bone infection. | a polyphasic taxonomic study was performed on two gram-positive-staining, anaerobic, pleomorphic, rod-shaped strains isolated from human bone and tissue samples. sequencing of the 16s rrna genes revealed that the strains belong to a novel species within the genus propionibacterium, most closely related to propionibacterium acnes subsp. acnes and propionibacterium acnes subsp. elongatum with similarity values of 98.4 % and 98.1 %, respectively. in addition, protein-coding genes for rpob, reca and ... | 2016 | 27259292 |
| propionibacterium acnes biofilm - a sanctuary for staphylococcus aureus? | the purpose of this study was to measure the effect of combined culture of propionibacterium acnes and staphylococcus aureus on biofilm formation under different oxygen concentrations. we measured planktonic growth and biofilm formation of p. acnes and s. aureus alone and together under aerobic and anaerobic conditions. both p. acnes and s. aureus grew under anaerobic conditions. when grown under anaerobic conditions, p. acnes with or without s. aureus formed a denser biomass biofilm than did s. ... | 2016 | 27241780 |
| unusual acute onset of abdominal aortic endograft infection by propionibacterium acnes after coil embolization for type ii endoleak. | propionibacterium acnes, an anaerobic gram-positive bacillus that inhabits the skin, has rarely been incriminated in abdominal aortic endograft infection. it is usually responsible for typical delayed and low-grade postoperative infections. we report the case of a 66-year-old patient who developed acute p. acnes aortic stent-graft infection 9 days after percutaneous embolization for type ii endoleak. the stent graft had been implanted 2 years before. because of persistent signs of sepsis and dis ... | 2016 | 27238987 |