Publications

the genetics and structure of the o-specific polysaccharide of yersinia pseudotuberculosis serotype o:10 and its relationship with escherichia coli o111 and salmonella enterica o35.	the o-specific polysaccharide (ops) is a variable constituent of the lipopolysaccharide of gram-negative bacteria. the polymorphic nature of opss within a species is usually first defined serologically, and the current serotyping scheme for yersinia pseudotuberculosis consists of 21 o serotypes of which 15 have been characterized genetically and structurally. here, we present the structure and dna sequence of y. pseudotuberculosis o:10 ops. the o unit consists of one residue each of d-galactopyr ...	2011	21321053
genetic analysis of the o-antigen gene clusters of yersinia pseudotuberculosis o:6 and o:7.	among the 21 o-polysaccharide (ops) o-antigen-based serotypes described for yersinia pseudotuberculosis, those of o:6 and o:7 are unusual in that both contain colitose (4-keto-3,6-dideoxy-d-mannose or 4-keto-3,6-dideoxy-l-xylo-hexose), which has not otherwise been reported for this species, and the o:6 ops also contains yersiniose a (4-c[(r)-1-hydroxyethyl]-3,6-dideoxy-d-xylo-hexose), another unusual dideoxyhexose sugar. in y. pseudotuberculosis, the genes for ops synthesis generally cluster tog ...	2011	21325338
the rack1 signaling scaffold protein selectively interacts with yersinia pseudotuberculosis virulence function.	many gram-negative bacteria use type iii secretion systems to translocate effector proteins into host cells. these effectors interfere with cellular functions in a highly regulated manner resulting in effects that are beneficial for the bacteria. the pathogen yersinia can resist phagocytosis by eukaryotic cells by translocating yop effectors into the target cell cytoplasm. this is called antiphagocytosis, and constitutes an important virulence feature of this pathogen since it allows survival in ...	2011	21347310
yersinia pseudotuberculosis is resistant to killing by human neutrophils.	the interaction between human neutrophils and the gram negative gastrointestinal pathogen yersinia pseudotuberculosis was investigated in vitro. despite the wealth of data describing how yersinia can affect the function of neutrophils, there are no published studies describing if neutrophil cells can affect the viability of y. pseudotuberculosis. the wild-type ip32953 strain of y. pseudotuberculosis was found to be resistant to killing by human neutrophils. confocal examination and flow-cytometr ...	2011	21354325
Antimicrobial Susceptibility and Distribution of ß-Lactamase A (blaA) and ß-Lactamase B (blaB) Genes in Enteropathogenic Yersinia Species.	One hundred eighty-six strains of enteropathogenic Yersinia (Y.) enterocolitica of bioserotypes 2/O:5,27, 2/O:9, 3/O:3, and 4/O:3 and 12 strains of Yersinia pseudotuberculosis of bioserotypes 1/O:1, 1/O:2, and 2/O:1 from different human (feces) and nonhuman (pig, pork, wild boar, monkey, chinchilla, mara, capybara, salad) sources collected in the years 1995-2009 were examined. Antimicrobial resistance patterns for 12 antimicrobial agents were generated using broth microdilution. The presence and ...	2011	21970627
Population structure of the Yersinia pseudotuberculosis complex according to multilocus sequence typing.	Multilocus sequence analysis of 417 strains of Yersinia pseudotuberculosis revealed that it is a complex of four populations, three of which have been previously assigned species status [Y. pseudotuberculosis sensu stricto (s.s.), Yersinia pestis and Yersinia similis] and a fourth population, which we refer to as the Korean group, which may be in the process of speciation. We detected clear signs of recombination within Y. pseudotuberculosis s.s. as well as imports from Y. similis and the Korean ...	2011	21951486
tubular immunostimulating complex based on cucumarioside a2-2 and monogalactosyldiacylglycerol from marine macrophytes.	there is an urgent need to develop safe and effective adjuvants for the new generation of subunit vaccines. we developed the tubular immunostimulating complex (ti-complex) as a new nanoparticulate antigen delivery system. the morphology and composition of ti-complexes principally differ from the known vesicular immunostimulating complexes (iscoms). however, methodology for the preparation of ti-complexes has suffered a number of shortcomings. the aim of the present work was to obtain an antigen ...	2011	21888630
impact of the n-terminal secretor domain on yopd translocator function in yersinia pseudotuberculosis type iii secretion.	type iii secretion systems (t3sss) secrete needle components, pore-forming translocators, and the translocated effectors. in part, effector recognition by a t3ss involves their n-terminal amino acids and their 5' mrna. to investigate whether similar molecular constraints influence translocator secretion, we scrutinized this region within yopd from yersinia pseudotuberculosis. mutations in the 5' end of yopd that resulted in specific disruption of the mrna sequence did not affect yopd secretion. ...	2011	21965570
rna helicase csda is needed for growth of yersinia pseudotuberculosis ip32953 at low temperature.	the expression of csda, encoding an rna helicase, was induced at 3°c in yersinia pseudotuberculosis. the role of csda in y. pseudotuberculosis at cold was confirmed by impaired growth of insertional csda mutants at 3°c. the results suggest csda is central for y. pseudotuberculosis survival in the chilled food chain.	2011	22156424
phosphorylated cpxr restricts production of the rova global regulator in yersinia pseudotuberculosis.	rova is a global transcriptional regulator of gene expression in pathogenic yersinia. rova levels are kept in check by a sophisticated layering of distinct transcriptional and post-transcriptional regulatory mechanisms. in the enteropathogen y. pseudotuberculosis, we have previously reported that the extracytoplasmic stress sensing cpxa-cpxr two-component regulatory system modulates rova expression.	2011	21876746
Effects of orange juice pH on survival, urease activity and DNA profiles of Yersinia enterocolitica and Yersinia pseudotuberculosis stored at 4 degree C.	The objective of this study was to determine the survival, growth rate and possible cellular adaptation mechanisms of Y. pseudotuberculosis and Y. enterocolitica in orange juice under different pH conditions. Yersinia was inoculated in orange juice with adjusted pH levels of 3.9, 4.0, and 7.0 and stored at 4 C for 3, 24, 72 and 168 hours (h). The inter-and intra-species variation is significant to the pH and time of incubation variables (p<0.05). At 3.9 pH the CFU (colony forming units) count de ...	2011	22081735
global discovery of small rnas in yersinia pseudotuberculosis identifies yersinia-specific small, noncoding rnas required for virulence.	a major class of bacterial small, noncoding rnas (srnas) acts by base-pairing with mrnas to alter the translation from and/or stability of the transcript. our laboratory has shown that hfq, the chaperone that mediates the interaction of many srnas with their targets, is required for the virulence of the enteropathogen yersinia pseudotuberculosis. this finding suggests that srnas play a critical role in the regulation of virulence in this pathogen, but these srnas are not known. using a deep sequ ...	2011	21876162
[the mode of spot test of plague and pseudotuberculosis agents mix cultures].	it is supposed to implement the polymerase chain reaction with mix of two pairs of "chromosome" primers "vlm12for'/"is216rev" and "js for"/jsrev" species-specific for y. pestis and y. psdtbc correspondingly in spot test of plague and pseudotuberculosis. the additional immunodiagnostics is applied to find defective and full-fledged on plague bacteria f1-antigen synthesis in the volume agglomeration reaction and paragglutination with diagnosticums of plasmid-dependent f1 antigen and chromosome fv ...	2011	21899119
PhoP and OxyR transcriptional regulators contribute to Yersinia pestis virulence and survival within Galleria mellonella.	The virulence of Yersinia pestis KIM6+ was compared with multiple isolates of Yersinia pseudotuberculosis and Yersinia enterocolitica toward larvae of the greater wax moth Galleria mellonella. Although Y. pestis and Y. pseudotuberculosis were able to cause lethal infection in G. mellonella, these species appeared less virulent than the majority of Y. enterocolitica strains tested. Y. pestis survived primarily within hemocytes of G. mellonella, and induced a strong antibacterial peptide response ...	2011	21964409
In vivo-induced InvA-like autotransporters Ifp and InvC of Yersinia pseudotuberculosis promote interactions with intestinal epithelial cells and contribute to virulence.	The Yersinia pseudotuberculosis Ifp and InvC molecules are putative autotransporter proteins with a high homology to the invasin (InvA) protein. In order to characterize the function of these surface proteins we expressed both factors in Escherichia coli K-12 and demonstrated attachment of Ifp- and InvC-expressing bacteria to human-, mouse- and pig-derived intestinal epithelial cells. Ifp was also found to mediate microcolony formation and internalization into polarized human enterocytes. The if ...	2011	22158741
Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.	Bioassay-guided fractionation of the CH(2)Cl(2)/MeOH extract of the Australian marine sponge Pseudoceratina sp. resulted in the purification of four new bromotyrosine alkaloids, pseudoceramines A-D (1-4), along with a known natural product, spermatinamine (5). The structures of 1-5 were determined by spectroscopic methods. Pseudoceramines A (1) and B (2) feature a rare bromotyrosyl-spermine-bromotyrosyl sequence, and pseudoceramine C (3) is the first example of bromotyrosine coupled with an N-me ...	2011	21850326
Development of Phage-Based Single Chain Fv Antibody Reagents for Detection of Yersinia pestis.	Most Yersinia pestis strains are known to express a capsule-like antigen, fraction 1 (F1)(.) F1 is encoded by the caf1 gene located on the large 100-kb pFra plasmid, which is found in Y. pestis but not in closely related species such as Yersinia enterocolytica and Yersinia pseudotuberculosis. In order to find antibodies specifically binding to Y. pestis we screened a large single chain Fv antibody fragment (scFv) phage display library using purified F1 antigen as a selection target. Different fo ...	2011	22174746
[primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden].		2011	3927607
disease transmission from companion parrots to dogs and cats: what is the real risk?	a number of common misconceptions exist regarding the degree of transmission from companion parrots to dogs and cats. concern regarding bacterial, viral, fungal, and parasitic transmission is generally unfounded, because disease transmission between companion parrots and dogs and cats is not well-documented. infections with mycobacterium spp, aspergillus spp, giardia spp, chlamydophila psittaci, salmonella spp, yersinia pseudotuberculosis, cryptococcus neoformans, histoplasma capsulatum, cryptos ...	2011	22041215
revision of the o-polysaccharide structure of yersinia pseudotuberculosis o:1a; confirmation of the function of wbym as paratosyltransferase.	an o-polysaccharide was isolated by mild acid degradation at ph 4.5 of the long-chain lipopolysaccharide of yersinia pseudotuberculosis pb1 (serotype o:1a) and studied using 2d nmr spectroscopy. it was found to contain two uncommon monosaccharides: paratose (3,6-dideoxy-d-ribo-hexose, par) in the furanose form and 6-deoxy-d-manno-heptose (d-6dmanhep). the following structure of a branched tetrasaccharide repeat (o-unit) with a disaccharide side chain was established: this structure is at varianc ...	2011	22269980
cloning, expression and characterization of the recombinant yersinia pseudotuberculosisl-asparaginase.	we have cloned ansb (yptb1411) gene from yersinia pseudotuberculosis q66cj2 and constructed stable inducible expression system that overproduce l-asparaginase from y. pseudotuberculosis (ypa) in escherichiacoli bl21 (de3) cells. for purification of ypa we used q-sepharose and deae-toyopearl column chromatography. we examined kinetics of the enzyme reaction, catalytic activity as a function of ph, temperature and ionic strength, thermostability and other enzyme properties. biochemical properties ...	2011	22226870
creation of a producent, optimization of expression, and purification of recombinant yersinia pseudotuberculosis l-asparaginase.	recombinant e. coli strain producing y. pseudotuberculosis q66cj2 (ypa) l-asparaginase ii was created. gene ansb homologue encoding y. pseudotuberculosis ip 32953 l-asparaginase precursor was synthesized. the gene was cloned in pbad24 expression vector and expressed in e. coli bl21 (de3) strain. optimal conditions for the producer strain culturing were selected. an effective method for isolation and purification of the enzyme by two-staged column chromatography was developed.	2011	22808465
[effect of phenol on yersinia pseudotuberculosis bacteria cultivated in various media].	study of bactericidal effect of phenol on yersinia pseudotuberculosis produced in various nutrient media. materials and methods: bacteria were produced in nutrient broth (nb) and nb with glucose (nb+glu) or galactose (nb+gal) at 8 degrees c. effect of phenol on bacteria was evaluated by changes in optical density of suspension and quantity of viable cells, and by staining of cells with ethidium bromide. lipids were analyzed by thin-layer and gas-liquid chromatography, gas-liquid- chromatography- ...	2011	22308732
pathogenetic role of yersinia pseudotuberculosis endotoxin in hemostasis and microcirculation disturbances.	we studied the role of y. pseudotuberculosis endotoxin (lps) in the pathogenesis of hemostasis and microcirculation disorders. it was found that changes in the hemostasis system after injection of lps had biphasic character corresponding to the stages of dic syndrome development. pathomorphological findings in animals with endotoxemia induced by y. pseudotuberculosis lps attested to increased permeability and destruction of the vascular endothelium in the microcirculatory bed and focal degenerat ...	2011	22235399
yersinia enterocolitica and yersinia pseudotuberculosis detection in foods.	yersinia enterocolitica and y. pseudotuberculosis which can cause yersiniosis in humans and animals are thought to be significant food-borne pathogens and be important as hygiene indicator in food safety. the pathogenic y. enterocolitica serotypes/biotypes are o:3/4 and 3 variant vp negative, o:5, 27/2, o:8/1b, and o:9/2, have been reported worldwide. y. pseudotuberculosis is distributed less widely than y. enterocolitica. isolation methods usually involve selective and recovery enrichment of th ...	2011	22567341
pathogenesis of y. enterocolitica and y. pseudotuberculosis in human yersiniosis.	yersiniosis is a food-borne illness that has become more prevalent in recent years due to human transmission via the fecal-oral route and prevalence in farm animals. yersiniosis is primarily caused by yersinia enterocolitica and less frequently by yersinia pseudotuberculosis. infection is usually characterized by a self-limiting acute infection beginning in the intestine and spreading to the mesenteric lymph nodes. however, more serious infections and chronic conditions can also occur, particula ...	2011	22567322
growth model of a plasmid-bearing virulent strain of yersinia pseudotuberculosis in raw ground beef.	the growth kinetics of virulence plasmid-bearing yersinia pseudotuberculosis (ypst) in sterile ground beef were studied at temperatures ranging from 0 to 30°c. in irradiated sterile ground beef, ypst replicated from 0 to 30°c, with corresponding growth rates (gr) ranging from 0.023 to 0.622 log cfu/h at 0-25°c, and the gr was 0.236 log cfu/h at 30°c. the maximum population densities (mpd) ranged from 8.7 to 11.0 log cfu/g. the growth and mpd of ypst were reduced significantly at 30°c. models for ...	2011	19912603
a novel ompy porin from yersinia pseudotuberculosis: structure, channel-forming activity and trimer thermal stability.	a novel ompy porin was predicted based on the yersinia pseudotuberculosis genome analysis. whereas it has the different genomic annotation such as "outer membrane protein n" (abs46310.1) in str. ip 31758 or "outer membrane protein c2, porin" (yp_070481.1) in str. ip32953, it might be warranted to rename the ompn/ompc2 to ompy, "outer membrane protein y", where letter "y" pertained to yersinia. both phylogenetic analysis and genomic localization clearly support that the ompy porin belongs to a ne ...	2011	21142221
development of a loop-mediated isothermal amplification assay for the detection of mycobacterium bovis.	bovine tuberculosis caused by mycobacterium bovis is an important zoonosis. in this study, a simple, rapid method for detecting this organism was developed based on loop-mediated isothermal amplification of the mpt83 gene. the technique will be of value in the clinical and field-based diagnosis of m. bovis and can differentiate it from other bacteria such as corynebacterium diphtheriae, streptococcus pneumoniae, β-haemolytic streptococci, pseudomonas aeruginosa, yersinia pseudotuberculosis, stap ...	2011	20138787
variation in the prevalence of enteropathogenic yersinia in slaughter pigs from belgium, italy, and spain.	tonsils of 829 fattening pigs originating from belgium (n = 201), italy (n = 428), and spain (n = 200) were collected between 2005 and 2007 to study the prevalence of enteropathogenic yersinia in slaughter pigs. isolation of yersinia enterocolitica and yersinia pseudotuberculosis was done by selective enrichment and by cold enrichment for 7 and 14 days. pathogenic y. enterocolitica and y. pseudotuberculosis isolates were identified by polymerase chain reaction targeting the chromosomal genes ail ...	2011	20187744
arthroplasty of the knee in rheumatoid arthritis and osteoarthritis. a follow-up study after implantation of the mckeever and macintosh prostheses.		2011	5054449
hemobilia due to ruptured hepatic artery aneurysm.		2011	3235180
[superior caliceal obstruction caused by vascular compression (fraley's syndrome)].		2011	3189028
k channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells.	by averaging the current that passes through cell-attached patches on beating heart cells, while measuring action potentials with a whole-cell electrode, we were able to study k channels during beating. in 7-d chick ventricle in 1.3 mm k physiological solutions at room temperature, delayed-rectifier channels have three linear conductance states: 60, 30, and 15 ps. the 60 and 15 ps conductances can exist alone, but all three states may appear in the same patch as interconverting conductance level ...	2011	3233269
[individual, reproducible temporomandibular joint radiograph].		2011	3166299
perinatal outcome, maternal weight gain, cigarette smoking and social status in jerusalem.	past studies have reported consistent depression of birthweight among offspring of mothers who smoked during pregnancy, but depression of maternal weight gain and increase in perinatal mortality have been inconsistent; these have been generally associated with smoking among women of low social status. among 8,263 pregnancies in west jerusalem from 1974 to 1976 to women who were not religiously observant, birthweight was low among infants of smokers, but maternal weight gain was not depressed nor ...	2011	3187144
cleavage lines of the oral mucosa in japanese cadavers.	cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.	2011	3165386
tourette syndrome and neuropsychiatric disorders: is there a genetic relationship?		2011	3165247
the role of substitutes in policy analysis: acute care services in state medicaid programs.	using four acute care equations (inpatient, physician, outpatient, and clinic) from a larger model of medicaid, this research examines the "contents" of policy outcomes. this closer examination of outcomes brings to light the interactions between redistributive programs and services and the role of substitutes and complements in state-level policy analysis. (a substitute is a benefit or service that can be used instead of another to produce a similar outcome; a complement is a benefit or service ...	2011	3049773
botulinum toxin a-induced protective ptosis in corneal disease.	botulinum toxin a produces a temporary, flaccid ptosis when injected into the levator palpebrae superioris muscle. the resulting protective ptosis was used to aid healing in 21 cases of indolent ulceration, and, prophylactically, in 4 cases of neuroparalytic keratitis. of the indolent ulcers, 90% healed completely. in all but one case, the cornea was covered completely by the lid and complete ptosis was produced in 75% of cases in an average of 3.6 days, lasting for 16 days on average before rec ...	2011	3050691
efficacy of oral acyclovir treatment of acute herpes zoster.	oral acyclovir, 800 mg five times per day for seven days, was compared with placebo in a randomized, double-blind trial conducted at three centers in the united kingdom. the study group consisted of 364 elderly immunocompetent patients with herpes zoster who were entered within 72 hours of the onset of rash. acyclovir significantly reduced the times to last new lesion formation (p less than 0.01), loss of vesicles (p less than 0.01), and full crusting (p = 0.03). no significant hastening of rash ...	2011	3044098
an on-line detection system for aerosols of proteolytic enzymes.		2011	3067643
catabolism of intracellular protein: molecular aspects.	all living cells regulate the content and composition of their resident proteins, but the mechanisms by which this is accomplished are not understood. the process of protein degradation has an important role in determining steady state and fluctuations of protein concentrations in mammalian cells. this process may be regulated by innate properties of the protein substrates, by factors that interact or "brand" proteins for degradation or by the degradative machinery of the cell. for a specific pr ...	2011	3017118
stability of tonic vergence.	tonic vergence was monitored at 30 min intervals over a 10 hr period of a single day and at intervals of approximately 14 days over a period of 19 weeks. measurements were also made during a continuous 112 min period in total darkness. tonic vergence showed neither significant systematic variation nor large random fluctuations during the course of either a day or weeks, demonstrating stability under naturally occurring viewing conditions. during the period in total darkness, however, tonic verge ...	2011	3170129
antithrombin iii, plasminogen, plasmin, and alpha-2-antiplasmin in donor blood and plasma components.	the functional levels of antithrombin iii, plasminogen, plasmin, and alpha-2-antiplasmin were evaluated in sequentially derived fresh frozen plasma, cryoprecipitate, and cryo-poor plasma aliquots from 20 registered blood donors. antithrombin iii is the major plasma inhibitor of the serine proteases of the procoagulant system. plasminogen, the proenzymatic form of plasmin, is the primary endogenous profibrinolytic moiety; alpha-2-antiplasmin is the principal intermediate acting inhibitor of plasm ...	2011	3158265
hospital visiting hours: time for improvement.	in a survey of hospital visiting hours in general medical and surgical wards throughout the united kingdom a pattern of visiting emerged showing that many hospitals still have very restricted visiting. a quarter of the 404 hospitals that responded permitted visiting for an average of two hours a day or less. in contrast, just over a third of hospitals allowed visiting for more than five hours a day. there was no relation between visiting times and type of hospital, but a striking regional variat ...	2011	3133059
[cavinton in the treatment of ischemic cerebral stroke. clinical and computerized-tomographic evaluation].	intravenous cavinton (ethyl ester of apovincaminic acid) was given to 27 patients with acute ischaemic stroke, while 30 patients were given aminophylline twice daily during 10 days. the results of this treatment was compared on the basis of clinical manifestations and changes in computerized tomograms (ct) before and after the treatment. it was found that cavinton gave similar results as aminophylline and other vasoactive preparations studied by other authors. in the group of severe strokes bett ...	2011	3537828
ethics committees.		2011	3220749
[effect of the background activity of a network of excitatory neuron-like elements on the conduction of excitation].	calculation on a mathematical model showed that for distortion-free conduction of excitation through a net of excitatory elements (ees) a system is necessary of optimum correlation of ees parameters, links between them and of external influences. when these parameters are deviated from their optimum values, excitation is conducted through the net either with attenuation or with intensification (as a result of divergence and convergence of the influences of the previous layer on the following one ...	2011	3195231
biochemical and other markers of colon cancer.	advances in the understanding of biochemical and molecular processes associated with cellular growth and differentiation, as well as colonic carcinogenesis hold promise for the development of new diagnostic and therapeutic modalities for this disease. altered glycosylation of cell surface and secreted glycoconjugates appear to be useful markers in differentiating normal from malignant colonic tissue. new information regarding deletion and inappropriate expression of several blood group-related c ...	2011	3068143
[congenital malformations of the female genital tract and gestation capacity].		2011	3232910
high progesterone/estradiol ratio in follicular fluid at oocyte aspiration for in vitro fertilization as a predictor of possible pregnancy.	eighteen women undergoing in vitro fertilization (ivf) procedures were studied. all had optimal (900 to 1600 pg/ml) peak serum estradiol (e2) response to the same stimulation regimen with clomiphene citrate and menotropins; fertilization rate was above 64%; and two to four embryos in two to eight cell stages were replaced in each patient. all were considered to have optimal chances for conception. the authors compared progesterone (p), e2, and p/e2 ratio in serum and follicular fluid (ff) at the ...	2011	3131157
the first international standard for antibodies to double stranded dna.	this paper announces the availability of the first international standard for anti-double-stranded dna (anti-dsdna). the material, coded wo/80, was obtained after recalcification of plasma taken from a patient with systemic lupus erythematosus. vials were filled with 500 microliters serum and freeze dried. the serum contains no other autoantibodies in measurable quantities. the vials should be stored at -20 degrees c. the standard should be used for establishing national, regional, or local stan ...	2011	3052322
[content of ldh isoenzyme and immunoglobulin in tears of patients with epidemic hemorrhagic conjunctivitis].		2011	3148425
development of training programmes in biotechnology safety and risk assessment.		2011	3228452
autotransplantation of maxillary canine teeth. a follow-up of 35 cases up to 4 years.	35 cases of autotransplantation of nonendodontically treated maxillary canines were followed for up to 4 years and were assessed according to loss of the transplanted tooth, onset of sensibility, mobility, intact lamina dura and presence of tooth resorption. the results of this study compare favourably with other studies and favour the hypothesis that little is to be gained by not endodontically treating autotransplanted teeth immediately after splint removal. it is also suggested that immobiliz ...	2011	3088156
ganglion cells in the turtle retina contain the neuropeptide lant-6.	this study investigated the presence of the neurotensin-related hexapeptide, lant-6, in retinal ganglion cells and their central projections in the turtle pseudemys scripta elegans. immunocytochemical techniques demonstrated that many of the cells in the ganglion cell layer of the turtle retina could be labeled with an antiserum specific for lant-6. radioimmunoassay and chromatographic analysis confirmed the presence of lant-6-related peptides in retina, as well as brain. several molecular forms ...	2011	3339403
hypoglycaemia in patients with insulin dependent diabetes.		2011	3133040
latest figures on aids.		2011	3133045
[acute pancreatitis: fluid accumulation in the lesser omental sac and retroperitoneum].		2011	3563061
adsorption of plasma proteins onto anticoagulant polystyrene derivatives: a fluorescence study.	quenching of fluorescence was used to monitor adsorption of thrombin (t), antithrombin (at) and their inactive complex (t-at) onto three anticoagulant biomaterials made of polystyrene beads bearing the functional groups of heparin. an adsorption capacity of 0.12 mumol of t per mg of polymer allowed the formation of a monolayer of protein at the polymer surface. an affinity constant of 3 x 10(7) l.mol-1 between thrombin and polymer was estimated, whatever the polymer used. the affinity of t-at wa ...	2011	3224125
[treatment of duodenogastric and gastroesophageal reflux].		2012	3420918
head and neck malignancies in children: an age-incidence study.	one hundred forty-seven (147) children under 18 years have been treated for head and neck malignancies at texas children's hospital from 1970 to 1985 and form the data base for this study. in order of frequency, the most common tumors were lymphoma, langerhans' histiocytosis (lh), rhabdomyosarcoma, neuroblastoma, and other soft-tissue sarcoma. children under 2 were most likely to have lh; those from 3 to 5, lh or lymphoma; and those over 5, lymphoma.	2012	3257285
liposarcoma in a canada goose (branta canadensis).	a multicentric liposarcoma was identified in various skeletal muscles of a mature canada goose. the light and electron microscopic appearance of the tumor is discussed in relation to the appearance of liposarcoma in other species.	2012	3442545
suspended scaffolding: proper protection reduces fall injuries.		2012	3347448
a.i.d. and aids--too close for comfort.		2012	3338577
primary malignant tumors of the liver.		2012	4321901
glycoprobe fructosamine kit used with the rotochem cfa 2000 centrifugal analyzer.		2012	3416449
to reduce or to integrate: psychiatry's dilemma.	three conceptual approaches to psychiatry may be distinguished: the somatic (biological); the psychological (psychodynamic, psychosocial); and the integrative (holistic, biopsychosocial). the first two emerged in the early nineteenth century, the third - in this century. all three continue to vie for influence today. the author traces their historical precursors and discusses their current state. he argues that psychiatrists need to apply methodological reductionism but adopt an integrative orie ...	2012	3518907
[polishing and the surface hardness of amalgams].		2012	3461499
[correlation between the arterial and pyelocaliceal systems].		2012	3685705
[correlation between the arterial and pyelocaliceal systems].		2012	3685705
occlusion of a hepatic arterial aneurysm with gianturco coils in a patient with the ehlers-danlos syndrome.	successful transcatheter occlusion of a proper hepatic arterial aneurysm in a patient with type iv ehlers-danlos syndrome is reported. this patient also had multiple, small intrahepatic arterial aneurysms, stenosis, and vascular occlusions. a spontaneous colonic perforation brought this patient to medical attention.	2012	3752386
occlusion of a hepatic arterial aneurysm with gianturco coils in a patient with the ehlers-danlos syndrome.	successful transcatheter occlusion of a proper hepatic arterial aneurysm in a patient with type iv ehlers-danlos syndrome is reported. this patient also had multiple, small intrahepatic arterial aneurysms, stenosis, and vascular occlusions. a spontaneous colonic perforation brought this patient to medical attention.	2012	3752386
exocrine pancreatic neoplasms induced by methylazoxymethanol acetate in the guppy poecilia reticulata.	exocrine pancreatic neoplasms developed in the guppy poecilia reticulata following a single brief exposure to methylazoxymethanol acetate [(mam-ac) cas: 592-62-1]. fish 6-10 days old were exposed to concentrations of mam-ac up to 100 mg/liter for 2 hours. exposed specimens were transferred to carcinogen-free water and sampled periodically for tumor development. pancreatic neoplasms occurred in approximately 9% of histologically examined individuals exposed to 10 mg mam-ac/liter or less. neoplast ...	2012	3470547
[plastic surgery of the ligamentous system of the knee joint].		2012	3431852
design of dental equipment for remote rural and field areas.	in the context of providing dental services, remote areas may be defined as those with overall low population densities; or isolated areas of low population density within more populous regions; or areas of high population density remote from dental services. the provision of equipment for remote areas is not simply a matter of extending the supply of conventional operatories to these regions. the particular needs of a region must be assessed first with equipment and instruments being selected t ...	2012	3468078
partial dissociation of spontaneous otoacoustic emissions and distortion products during aspirin use in humans.	otoacoustic emissions (oaes) of two types--spontaneous and evoked distortion products--were studied before, during, and following a period of aspirin use. as previously reported, aspirin consumption uniformly reduced the spontaneous oaes (soaes) to unmeasurable or extremely low levels. aspirin consumption also reduced the amplitude of the evoked distortion products (edps) but did not eliminate them entirely. the amplitude of the edp and its change with aspirin consumption were related to both th ...	2012	3411052
sensitizing effects of pretreatment measures on cancer chemotherapy nausea and vomiting.		2012	3346453
muscular contraction.		2012	3288085
cell and molecular analysis of long-term sensitization in aplysia.	we have found that one cellular locus for the storage of the memory underlying short-term sensitization of the gill and siphon withdrawal reflex in aplysia is the set of monosynaptic connections between the siphon sensory cells and the gill and siphon motor neurons. these connections also participate in the storage of memory underlying long-term sensitization. in animals that have undergone long-term sensitization, the amplitudes of the monosynaptic connections are significantly larger (2.2x) th ...	2012	3572827
prevalence of bronchial hyperresponsiveness in highly trained athletes.	previous studies indicated that the prevalence of symptomatic asthma is about 4 to 7 percent. no similar studies exist to suggest the prevalence of asthma in highly trained competitive athletes, since asthma is thought to be an uncommon disease in this population. we became concerned, therefore, when a large number of football players developed symptoms consistent with asthma during preparation in california for the rose bowl in december 1981. we studied the team and found 12 percent of the foot ...	2012	3522119
[nursing care of patients with cerebrovascular disorders].		2012	3427734
[therapy of alcoholic hepatitis].		2012	3545753
[therapy of alcoholic hepatitis].		2012	3545753
endogenous digitalis-like immunoreactive substances in cord serum characterized by anti-digitoxin and anti-digoxin antibodies. effect of modulated incubation conditions.	digoxin-like immunoreactive substances (dlis) have been extensively described in biological fluids of pregnant women, neonates and renal impaired patients, by the use of several digoxin immunoassays. in this paper a similar interference with anti-digitoxin antibodies is reported by investigating 20 cord sera. by increasing both the time and the temperature of the incubation, the levels of digitalis-like immunoreactive substances may be modulated and decreased to zero. digitoxin- and digoxin-like ...	2012	3530526
urinary retention secondary to a gartner's duct cyst.	a 22-month-old child with a large cyst of gartner's duct suffered from recurrent episodes of urinary retention. excision of such large symptomatic cysts has been recommended in the past. marsupialization is discussed as an alternative to extensive excision.	2012	3405570
blood glucose control and diabetic complications.	two hypotheses have been advanced to explain the appearance of microvascular complications in diabetic patients with glycemic control. the genetic hypothesis suggests that the development of diabetic complications is genetically determined and independent of diabetic control, whereas the metabolic hypothesis suggests that long-term hyperglycemia causes the subsequent development of small-blood-vessel complications. we review data that either support or reject these hypotheses and suggest a third ...	2012	3524339
nocturnal hypoglycemia as a cause of fasting hyperglycemia (somogyi phenomenon)		2012	3285217
traumatic myositis ossificans in masticatory muscles.	3 cases of traumatic myositis ossificans circumscripta, located within the masticatory muscles are presented. two of the lesions involved the masseter muscle, and exceptionally, 1 involved the temporalis muscle. three pathognomonic histological zones, permitting the differential diagnosis of myositis ossificans from sarcomatous lesions, are described, and treatment incorporating ideally early surgical intervention with wide excisional biopsy of the lesion is stressed.	2012	3461100
vitamin e and cell injury.		2012	3386907
[pure sensory stroke caused by thalamic hematoma].	a 59-year-old hypertensive patient presented with dysesthesias and a pure sensory deficit involving face, arm and leg on the left side of the body. ct scan and mri showed a small hematoma in the posterior and lateral part of the right thalamus.	2012	3368695
evaluation of bronchodilator responsiveness in mechanically ventilated patients.	airway pressure, flow, and volume were measured before and after administration of aerosolized metaproterenol during controlled mechanical inflation and stepwise deflation of the relaxed respiratory system in 13 mechanically ventilated patients. an increase in passive expiratory flow at constant respiratory system recoil pressure was considered evidence of bronchodilatation. in 10 patients, at a respiratory system recoil pressure of 6 cm h2o (vp6), expiratory flow increased 21 to 500% above preb ...	2012	3310772
[urinary excretion of beta 2 microglobulin in workers chronically exposed to various heavy metals].	increased urinary excretion of beta-2-microglobulin (b2m) is regarded as one of the earliest indices of the lesion of renal tubules. a great usefulness of the determination of this protein has been demonstrated in workers chronically exposed to heavy metals. the investigations have been carried out in 79 workers chronically exposed to cadmium, 39 workers chronically exposed to mercury and 31 non-exposed subjects. the urinary b2m concentration in all subjects was determined using the radioimmunoa ...	2012	3528739
renal functional reserve of transplanted kidneys.		2012	3534610
isolated hypoaldosteronism and abnormalities in renin, kallikrein, and prostaglandin.	to further define the pathophysiology of the syndrome of acquired isolated hypoaldosteronism, we determined plasma concentrations of active and inactive renin and urinary kallikrein and prostaglandin e2 excretion rates in 11 patients with the syndrome, 12 patients with similar serum creatinine levels, but without hyperkalemia, and in 12 normotensive patients with normal renal function and low plasma renin activities (pra). ten of 11 patients with the syndrome had low baseline pra, and, unlike th ...	2012	3523269
[treatment of severe acute asthma in adults].	although abnormal blood gases are unusual in status asthmaticus, hypercapnia indicates a considerable increase in bronchial resistance. the authors report their experience of 106 personal cases of acute severe asthma. emergency management of acute respiratory failure consisted in symptomatic therapy (low rate oxygen or mechanical ventilation after nasal intubation). corticosteroids, rehydration, antibiotics and beta-2 adrenergic agents were associated. mechanical ventilation was necessary in pat ...	2012	3706959
cerebral hemispheric and contralateral cerebellar hypoperfusion during a transient ischemic attack.	we studied a 79-year-old woman within 3 h of the onset of a motor aphasia and a right hemiparesis. single photon emission computed tomography (spect) showed a 24% decrease in the perfusion of the left middle cerebral artery territory and a 16% reduction in the perfusion of the right cerebellum. a mild naming difficulty was the neurological deficit at the end of the spect examination, and complete recovery was achieved within 24 h. repeated spect study 10 days later was normal. this is the first ...	2012	3497164
personal computers: their use in a low-volume imaging department.		2012	3486574
splenic migration of xid and non-xid splenic b cells.	the x-linked immune deficiency gene (xid) has been viewed as inducing either a deficiency in a b-cell subset or in b-cell maturation. the present experiments were performed in an attempt to better understand whether (a) xid b cells migrate differently from mature and immature non-xid b cells, and (b) whether the failure of mature b cells to be found in xid spleen, but not peyer's patches, is secondary to migratory differences, especially the possible inability of xid spleens to receive mature b ...	2012	3486071