Publications

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crystal formation by a ribonucleic acid polymerase mutant of bacillus subtilis.a crystalline inclusion has been observed in a ribonucleic acid polymerase mutant of bacillus subtilis which is conditionally temperature sensitive only during sporulation. the crystal is formed at the permissive temperature in 1 to 2% of the sporulating (stage iii-iv) cells; about 85% of the cells sporulate normally, while the cells with crystals do not sporulate. the wild type does not form crystals at either the permissive (30 c) or the nonpermissive (47 c) temperatures. the crystal may resul ...19734126822
studies on bacillus subtilis bacteriophage phi 15. 19734126839
feulgen-derived techniques for electron microscopical cytochemistry of dna. 19734127220
the effect of cationic compounds of biological origin on the heat resistance of bacillus subtilis spores. 19734127816
characterization of bleomycin-resistant dna.after reaction of dna with high concentrations of bleomycin, approximately 80% of the dna becomes trichloroacetic acid (tca) soluble. the remaining 20% of the dna remains tca insoluble. upon further treatment of this tca-insoluble material with high concentrations of the drug, no further drug action can be detected. drug action is defined as fragmentation of dna to smaller molecular size, release of free bases, and tca solubilization. this material which is not attacked by bleomycin has been ter ...19734128368
uptake of bacterial dna by chlamydomonas reinhardi. 19734133557
proceedings: the effect of sporulation temperature upon the post-germinative resistance of bacillus subtilis. 19734150530
[subtilin, vi: the structure of subtilin (author's transl)]. 19734154277
disturbance of immune system in mice by administration of 7,12-dimethylbenz(a)anthracene and normal thymocytes. 19734205230
production of bacterial amylase on some commercial materials. 19734205242
optimal conditions for production of bacterial amylase. 19734205243
[asimple apparatus for measuring the efficiency of quick acting disinfectants and sterilizing solutions. application to the action of sodium hypochlorite against bacterial spores]. 19734205286
antimetabolites produced by microorganisms. vii. l-(n5-phosphono)methionine-s-sulfoximinyl-l-alanyl-l-alanine. 19734205374
studies on the antiviral substance. mechanism of action of bihoromycin, a new antibiotic. 19734205375
[the effect of bacillus subtilis alpha-amylase on starch]. 19734205437
the characteristic action patterns of crystalline bacterial saccharifying alpha-amylase independent of its microheterogeneity. 19734205461
[relationship between the instability in saline and the competence for genetic transformation in bacillus subtilis]. 19734205483
follow-up of a group of workers exposed to dusts containing derivatives of bacillus subtilis. 19734205552
clinical and immunological responses to enzymes of bacillus subtilis in factory workers and consumers. 19734205553
mutants of bacillus subtilis blocked in acetoin reductase. 19734205556
[toxicological studies of enzymatic preparations intended for use in the food industry]. 19734205601
maridomycin, a new macrolide antibiotic. i. taxonomy and fermentation. 19734205650
[studies on the combination action of synthetic penicillins, hetacillin and dicloxacillin (author's transl)]. 19734205655
[membranous structures of bacillus subtilis cells revealed by a negative contrast method]. 19734205726
chemical modification of neutral subtilopeptidase by aromatic diazo compounds. 19734205761
studies on the antitumor activity of an alazopeptin isolated from a new strain of streptomyces. 19734205875
letter: the probable identity of bacilysin and tetaine. 19734205876
recombination deficient mutants of e. coli and other bacteria. 19734205905
characterisation & identification of two aerobic spore forming bacteria producing extracellular glutamic acid & valine respectively. 19734205940
investigation of the protease forming ability of serratia marcescens and one of its mutant strains. 19734205979
mechanism of the formation of concanavalin a-teichoic acid complexes. 19734206131
amidase activity of human alpha-macroglobulin. 19734206274
stimulation of non-conservative dna synthesis by ultraviolet light in freeze-treated bacillus subtilis. 19734202756
control of metabolite secretion in bacillus subtilis. 19734202781
on the amino-acid sequence of flagellin from bacillus subtilis 168: comparison with other bacterial flagellins.a partial amino-acid sequence of bacillus subtilis 168 flagellin is presented. the region of unassigned sequence in this 304-residue polypeptide chain spans residues 158-173. comparison of the 27-residue aminoterminal cnbr peptide of b. subtilis 168 flagellin with that derived from the flagellin of the serologically unrelated strain of b. subtilis, w23, shows only three conservative substitutions, whereas the 16-residue carboxyl-terminal peptides derived from these flagellins were identical. the ...19734202846
the occurrence of two types of synthesis of deoxyribonucleic acid during normal growth in bacillus subtilis.a study of the relative utilization of thymine and thymidine as precursors for dna synthesis during normal growth in bacillus subtilis showed that thymine serves preferentially as a precursor for ;repair' synthesis, whereas thymidine is used preferentially for ;replicative' synthesis. further, evidence was obtained which suggests that during normal growth both ;replicative' and ;repair' dna syntheses occur simultaneously. ;repair' synthesis is distinguished not only on the basis of its preferent ...19734202939
the structure of a polymer containing galactosamine from walls of bacillus subtilis 168.cell walls of bacillus subtilis 168 contain a phosphorylated polysaccharide composed of n-acetylgalactosamine, glucose and phosphate. controlled acid hydrolysis gives 3-o-beta-d-glucopyranosyl-n-acetylgalactosamine with a phosphomonoester group at the 6-position of glucose. it is likely that the polysaccharide consists of disaccharide units connected by phosphodiester residues joining the 1-position of n-acetylgalactosamine to the 6-position of glucose in the neighbouring unit.19734202940
protection by histidine from inactivation of dna transforming activity by near-ultraviolet light (365 nm) compared with far-ultraviolet light (254 nm). 19734204254
biochemical genetics of bacterial sporulation. iv. sequential development of resistances to chemical and physical agents during sporulation of bacillus subtilis. 19734204357
effect of iron deprivation and temperature upon bacterial survival. 19734204389
two forms of the dna ligase of human cells. 19734204425
synthesis of the unusual dna of bacillus subtilis bacteriophage sp-15.cultures of bacillus subtilis infected with phage sp-15 were examined to investigate the metabolic origin of two of the unique components of the phage dna: the component responsible for the unusually high buoyant density in cscl and the unusual pyrimidine, 5-(4', 5'-dihydroxypentyl) uracil (dhpu). newly synthesized pulse-labeled dna was light in buoyant density and shifted to the high density of mature phage dna upon further incubation. parental dna was converted to a light-density intermediate ...19734203083
viral protein synthesis in bacteriophage phi 29-infected bacillus subtilis.twenty-three (14)c-labeled phage phi29-specific proteins in lysates of uv-irradiated bacillus subtilis have been resolved by sodium dodecyl sulfate polyacrylamide gel electrophoresis and identified by autoradiography. included in this group of proteins are the six major structural proteins of the virion. analysis of the temporal sequence of viral protein synthesis indicates that three groups of proteins can be identified by time of appearance, beginning at 2 to 4, 4 to 6, or 8 to 10 min after in ...19734203085
regulation of transport systems: a means of controlling metabolic rates. 19734203320
[production of levorin in mixed cultures with different microorganisms]. 19734203328
scanning electron microscopy of bacterial colonies.a technique is described for observing bacterial colony growth. bacillus cereus, b. subtilis, and b. cereus var. mycoides were grown on strips of dialysis membrane layered on nutrient agar. microcolonies of the organisms on strips were fixed in formalin vapor in situ; the strips then were removed from the agar and secured to scanning microscope specimen stubs without markedly disturbing the cellular arrangement. scanning electron micrographs clearly depict morphology of individual cells, as well ...19734203336
a new polypeptide associated with rna polymerase from bacillus subtilis during late stages of vegetative growth. 19734203344
[comparative study of bacterial thermophily in the genus bacillus (author's transl)]. 19734204528
the conversion of bisnorbiotin and bisnordethiobiotin to biotin and dethiobiotin, respectively, by microorganisms. 19734204631
letter: crystal-like structure in the sporulating cells of bacillus subtilis 168. 19734204687
minicells of bacillus subtilis: a new bacteriophage-blocking agent.bacteriophage sp01, sp17, and phi29 rapidly absorb irreversibly to minicells of bacillus subtilis but do not produce a lytic cycle in minicells.19734204693
[use of mathematical methods in planning an experiment to choose the optimum medium for the synthesis of inosine by a culture of bacillus subtilis gene-265]. 19734204737
repair of uv-damaged dna by competent and incompetent bacillus subtilis cells. 19734204834
a rapid micro-assay of gentamicin, kanamycin or streptomycin in serum containing penicillins or cephalosporins. 19734205062
aspects of the pharmacology of gentamicin during the neonatal period. 19734205063
pseudomonas bacteremia. evaluation of factors influencing response to therapy. 19734205064
membrane leakage in bacillus subtilis 168 induced by the hop constituents lupulone, humulone, isohumulone and humulinic acid. 19734205069
[activation of dna ligase in bac. subtilis cells irradiated with ionizing radiation]. 19734205079
[intensive disproportionate flow culture of paramecium caudatum]. 19734205167
an enzyme preparation inactivating all penicillins and cephalosporins.commercial penicillinases vary in their capacity to destroy penicillinase-resistant penicillins and cephalosporins. a new freeze-dried preparation containing both beta-lactamase i and ii was found to inactivate all penicillins and cephalosporins at levels above those likely to be encountered in clinical specimens.19734200322
[the spreading of organisms in aseptic departments by rubber overshoes]. 19734200342
the formation of pyrimidine dimers in the dna of fungi and bacteria. 19734200353
asymmetric transcription of spp1 in vivo. 19734200375
affinity chromatography of thermolysin and of neutral proteases from b. subtilis. 19734200397
recent evidence on trna and trna acylase-mediated cellular control mechanisms: a review. 19734199831
[experimental studies on absorption, excretion, distribution and metabolism of 3',4' dideoxykanamycin b. 1. absorption, excretion, distribution and metabolism in rats]. 19734199875
precursors of 5 s ribosomal rna in bacillus subtilis. 19734200018
effects of physical and chemical agents on competing- and transforming-abilities of dna in bacillus subtilis. 19734200132
inhibitory effect of antibiotic wr-142 on synthesis of nucleic acids and proteins in b. subtilis cells. 19734200158
pleiotropic menaquinone-deficient mutant of bacillus subtilis.a multiple aromatic amino acid auxotroph of bacillus subtilis 168 has been isolated which is unable to synthesize menaquinone-7 (mk-7) unless supplied with shikimic acid (shk). the mutant, rb163, was isolated by selecting for resistance to low levels (1.5 mug/ml) of kanamycin. enzymatic and genetic analyses show that the strain is an arod mutant lacking 5-dehydroshikimate reductase. under growth conditions in which its mk-7 deficiency is expressed, rb163 is deficient in cytochromes a, b, and c, ...19734199502
phenotypes of pleiotropic-negative sporulation mutants of bacillus subtilis.the phenotypic properties of representatives of the five genetic classes of pleiotropic-negative sporulation mutants have been investigated. protease production, alkaline and neutral proteases, was curtailed in spoa mutants, but the remainder of mutant classes produced both proteases, albeit at reduced levels. the spoa and spob mutants plaqued phi2 and phi15 at high efficiency, but the efficiency of plating of these phages on spoe, spof, and spoh mutants was drastically reduced. antibiotic was p ...19734199504
ethidium bromide-resistant mutant of bacillus subtilis.an ethidium bromide-resistant mutant (eb8) derived from a marburg strain of bacillus subtilis was found to be conditionally resistant to 10 mug of ethidium bromide per ml. expression of resistance is complete only during vegetative growth at incubation temperatures above 30 c in complex medium or minimal medium supplemented with casamino acids. strain eb8 is cross-resistant to acriflavine and proflavine. the ethidium bromide resistance marker is co-transduced with hisa1 at a frequency of 6% and ...19734199505
genetic mapping of a mutant defective in d,l-alanine racemase in bacillus subtilis 168.genetic analysis of a d-alanine requiring mutant (dal) of bacillus subtilis reveals that the gene that codes for d,l-alanine racemase is linked to purb. the order of genes in this region of the chromosome is purb, pig, tsi, dal. thus there are at least two clusters of genes that regulate cell wall biosynthesis in b. subtilis.19734199510
genetic and biochemical characterization of mutants of bacillus subtilis defective in succinate dehydrogenase.eleven succinate-accumulating mutants of bacillus subtilis have been mapped by transformation and transduction crosses and characterized with respect to activities of citric acid cycle enzymes. these mutants could be divided into three genetic groups. nine of the mutants were found to map between arga and leu in the citf locus. a second group was located between lys-1 and trpc2 and the third group could not be located on the b. subtilis chromosome in extensive transduction crosses. all of the ci ...19734199512
threonine synthetase-catalyzed conversion of phosphohomoserine to alpha-ketobutyrate in bacillus subtilis.an enzyme activity of bacillus subtilis has been found that catalyzes the dephosphorylation and deamination of phosphohomoserine to alpha-ketobutyrate, resulting in a bypass of threonine in isoleucine biosynthesis. in crude extracts of a strain deficient in the biosynthetic isoleucine-inhibitable threonine dehydratase, phosphohomoserine was converted to alpha-ketobutyrate. phosphohomoserine conversion to alpha-ketobutyrate was shown not to involve a threonine intermediate. single mutational even ...19734199513
lipopolysaccharide layer protection of gram-negative bacteria against inhibition by long-chain fatty acids.growth, amino acid transport, and oxygen consumption of escherichia coli and salmonella typhimurium are inhibited by short-chain (c(2)-c(6)) but not by medium or long-chain fatty acids (c(10)-c(18)) at concentrations at which these processes are completely inhibited in bacillus subtilis. the resistance of gram-negative organisms is not correlated with their ability to metabolize fatty acids, since an e. coli mutant unable to transport oleic acid is still resistant. however, mutants of both e. co ...19734199515
[study of the possibility of modifying radiation damage to mammalian cells by bacterial dna ligase]. 19734199540
human immunoglobulin a: production of an fc fragment by an enteric microbial proteolytic enzyme. 19734199558
electron microscope study of the structures of the bacillus subtilis prophages, spo2 and phi105. 19734199564
electron microscope mapping of the distribution of ribosomal genes of the bacillus subtilis chromosome. 19734199565
the localization of dna ligase in the chromatin of animal cells. 19734199647
influence of fungicides on mycotoxin production by alternaria mali. 19734199668
comparison of bacillus thuringiensis with other bacillus species based on enzymoserological examinations of their proteolytic enzymes. 19734199697
structure and synthesis of the ribosomal ribonucleic acid of prokaryotes. 19734203396
proceedings: netherlands society for microbiology meeting at utrecht on 2 may 1973. chemotaxis in microorganisms. 19734203453
proceedings: netherllands society for microbiology meeting at utrecht on 2 may 1973. environmental effects on bacterial wall synthesis. 19734203454
biological production of 5-methylthioribose. 19734203512
[sterilization of transplantation material]. 19734203567
[comparative study of microbial protease complexes]. 19734203666
[fine structure, biological properties and intracellular development of phage pbs21 in bacillus subtilis cells]. 19734203669
[the radiosensitivity of different conformations of native dna in solution]. 19734203880
[chemical protection of transforming dna]. 19734203881
quantitative studies on the drainage of the cerebrospinal fluid into the lymphatic system. 19734203896
transformation of bacillus subtilis using gently lysed l-forms; a new mapping technique. 19734203903
comparative immunological and electrophoretic studies on ribosomal proteins of bacillaceae. 19734203929
comparison of ribosomal rna-binding protein "l2" isolated from different bacterial species. 19734203930
erythromycin resistant mutants of bacillus subtilis. 19734203931
chloramphenicol resistant mutants of bacillus subtilis. 19734203932
[conditions for coagulation of the biomass of a culture of bacillus subtilis 103]. 19734203935
the kinetics of extracellular protease production in an abnormal sporulation mutant of b. subtilis. 19734203947
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