Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| hemophilus influenzae infections in adults. | 1978 | 366294 | |
| quantitative determination of alpha-amylase in glucoamylase preparations. | 1978 | 347977 | |
| use of the minitek system for biotyping haemophilus species. | the minitek system was used for characterization and identification of haemophilus. the system was simple to use and provided rapid and clear-cut test results. | 1978 | 348723 |
| survival of upper respiratory tract bacteria on cotton-wool swabs. | plain, buffered cotton-wool swabs and albumen-coated cotton-wool swabs were prepared with known numbers of the following: haemophilus influenzae, streptococcus pneumoniae, staphylococcus aureus, corynebacteria and escherichia coli. swabs were plated immediately (0 hours) after loading with a 0.1 ml standardised inoculum; each swab was plated out four times by streaking on both halves of two plates. at 0 hours recovery rates from first platings on solid media ranged from 3.3%-8.9%; from platings ... | 1978 | 348727 |
| cefamandole vs. procaine penicillin for treatment of pneumonia due to streptococcus pneumoniae: a random trial. | the efficacy and safety of cefamandole nafate and penicillin g procaine suspension were compared in the treatment of pneumococcal pneumonia in hospitalized adults. one hundred thirteen patients with clinical and radiographic evidence of pneumococcal pneumonia were randomly assigned to receive 600,000 units of procaine penicillin intramuscularly every 12 hr or 500 mg of cefamandole intramuscularly every 6 hr. the two groups were comparable with regard to patient type and extent and severity of pn ... | 1978 | 349092 |
| clinical and laboratory investigation of cefamandole therapy of infections in infants and children. | cefamandole nafate was effective in the treatment of a variety of infections caused by staphylococcus aureus, streptococcus pyogenes group a, streptococcus pneumoniae, and haemophilus influenzae in infants and children. the infections included periorbital cellulitis and ethmoiditis, bacteremia, cellulitis, pneumonia, and lymphadenitis. in vitro, cefamandole was effective in inhibiting the growth of h. influenzae isolated from blood or cerebrospinal fluid of patients with meningitis or sepsis. in ... | 1978 | 349094 |
| antibacterial activity of cefamandole in vitro. | cefamandole, a new cephalosporin derivative, was found to have a broad spectrum of antimicrobial activity against a cross-section of both gram-positive and gram-negative bacteria isolated clinically. gram-positive cocci, except for streptococcus faecalis, were extremely susceptible to cefamandole; penicillin g-resistant staphylococcus aureus also was highly susceptible. minimal bactericidal concentrations for gram-positive cocci approximated the minimal inhibitory concentrations. strains of haem ... | 1978 | 349095 |
| mechanisms of reaginic hypersensitivity and immunotherapy. | reaginic antibodies in hay fever patients belong to ige. the immunoglobulin sensitizes basophilic granulocytes and mast cells from homologous species and mediates the release of chemical mediators which cause allergic symptoms. the sensitization is due to the binding of ige to receptors on the target cells through the fc portion of the molecules. high affinity of the molecules for the receptor is responsible for the biologic activity of ige antibodies and for the persistence of sensitization wit ... | 1978 | 351300 |
| extraneuronal uptake and metabolism of catecholamines as a site of loss. | 1978 | 351318 | |
| prehistoric new zealanders. | the physical condition of prehistoric man in new zealand is briefly surveyed. these were tall, robust polynesian people living an active existence, and having an adequate diet. the mean life span of about 30 years for adults was short only by modern western standards. a number of skeletal features, notably aspects of skull and long bone form, set them apart from other races of mankind. | 1978 | 351477 |
| the interconversion of conformers of phenylalanyl-trna with different affinity to 70s ribosomes of escherichia coli. | earlier the existence of two conformers of phe-trnaphe of e. coli was demonstrated because one of them yields complexes with 70s-poly(u) of extremely high affinity and the other with at least a 105 lower binding constant. we denote the first conformer as hac (high affinity conformer) and the second as lac (low affinity conformer). this high difference in binding constants was used for studying the process of reversible interconversion of conformers of phe-trnaphe. the transition kinetics of lac ... | 1978 | 351562 |
| anti-m in children with acute bacterial infections. | four children, 7 to 24 months old, were found to have anti-m at the time of admission to the hospital for severe acute bacterial infections. all were m-n+. two patients had meningitis, one had septic arthritis, and the fourth had a third-degree burn of the left hand. in follow-up studies the anti-m of patients no3 and no4 were no longer detectable after 12 and 11 months respectively. in all patients no demonstrable antibody was in either maternal or cord sera at time of birth. the clinical data ... | 1978 | 351884 |
| replication of a nuclear polyhedrosis virus in a continuous cell line of spodoptera frugiperda: partial characterization of the viral dna, comparative dna-dna hybridization, and patterns of dna synthesis. | 1978 | 351928 | |
| acid precipitation of clostridium botulinum type c and d toxins from whole culture by addition of ribonucleic acid as a precipitation aid. | the ratios of ribonucleic acid to protein contents of clostridium botulinum type c, d, and e cultures were lower than those of type a, b, and f cultures. addition of ribonucleic acid at 0.4 mg/ml to culture satisfactorily aided acid precipitation of type c and d toxins, but not that of type e toxin. | 1978 | 344224 |
| a rapid slide test for penicillinase. | the authors developed a rapid slide test modification of the iodometric method for detection of penicillinase produced by organisms growing on routine plating media. a loopful of colonies is scraped from the agar surface and emulsified in one drop of an iodine-penicillin solution on a glass slide. addition of a drop of 0.4% starch solution results in a purple color when penicillinase is not present; a colorless reaction denotes a positive test. the slide test yielded positive results identical t ... | 1978 | 345799 |
| restriction endonucleases and modification methylases in bacteria. | 1978 | 346412 | |
| molecular properties of transmissible r factors of haemophilus influenzae determing tetracycline resistance. | the tetracycline-resistant haemophilus influenzae strains lu121 and fr16017, recently isolated in west germany, each harbour a plasmid; that of the former (plu12u) has a mol. wt of 31.5 x 10(6) and that of the latter (pfr16017) has a mol. wt of 33 x 10(6). conjugation and dna-dna hybridization studies have shown that both plasmids are self-transmissible and carry tetracycline-resistance genes. the purified plasmid dna of h. influenzae strain lu121 transformed a sensitive escherichia coli strain ... | 1978 | 347029 |
| hemophilus influenzae type b disease in a day-care center. report of an outbreak. | four episodes of serious hemophilus influenzae type b infection occurred in three children attending a day-care center. this was 100 times the expected annual total. the pharyngeal carriage rate of hib was 60% for siblings of patients, 20% for adult household contacts, and 5% for well children at the center. no carriers were found in control populations. escherichia coli k100, which cross-reacts serologically with hib, was found in rectal swabs of 20% of family contacts of patients and 3.5% of w ... | 1978 | 347042 |
| late sequelae of adult-onset acute bacterial nephritis. | the late manifestations of adult-onset acute bacterial nephritis were studied in four patients from 4 months to 5.6 years following initial infection. an unusual combination of generalized (global) wasting of the kidney and focal calyceal clubbing developed within a few weeks of the acute infection. the pattern of calyceal deformity strongly suggests papillary necrosis; it may develop during the acute phase, but go unrecognized during excretory urography at that time because of impaired contrast ... | 1978 | 347494 |
| naturally occurring anti-kell stimulated by e. coli enterocolitis in a 20-day-old child. | anti-a and anti-k have been found in the serum of a 20-day-old child who had not been transfused but who was acutely ill with e. coli enterocolitis. both antibodies are igm proteins. the mother's serum does not contain either antibody and the anti-a and anti-k in the infant's serum are not of maternal origin. both parents and the child are of the kell phenotype k-k+. stool cultures made from the child yielded e. coli o 125:b15, an uncommon b-variant pathogenic coliform. cell-free preparations ma ... | 1978 | 347643 |
| [pleural empyema and tauroflex. study of a new bactericidal agent]. | a pilot study of 8 cases of lung empyema treated with taurolin, a new bactericidal agent, is reported. rapid sterilization of exudates and favorable clinical course are discussed. thanks to the absence of toxicity and its bacteriological efficacy, taurolin is a useful therapeutic agent in pleural empyema. its use in the prophylaxis of complications in thoracic surgery is suggested. | 1978 | 341304 |
| experimental and clinical immunopathology of middle ear transplantation. | on the basis of experimental data the concept of immuno-tolerance in allograft-tympanoplasty is discussed. immunological interference in human tympanic membrane grafts has been demonstrated by means of t-cell membrane fluorescence. | 1978 | 310740 |
| characterization of lipopolysaccharide of haemophilus influenzae. | lipopolysaccharide from strains of haemophilus influenzae was extracted and isolated by the hot phenol-water procedure. the preparations were relatively insoluble in water but could be solubilized with surface-active agents. the preparations contained carbohydrate (30%), fatty acid (29%), and phosphate (4.7%); protein content was less than 1%. thin-layer chromatography, gas-liquid chromatography, and colorimetric assays detected glucose, galactose, glucosamine, heptose, and a 2-keto-3-deoxy-octo ... | 1978 | 310855 |
| utility scaling of intracranial reinforcement duration. | 1978 | 311015 | |
| human mucosal lymphocytes - memory for 'recall' antigens and non-specific suppression by t-lymphocytes. | 1978 | 311142 | |
| [the influence of cryoprotective solutions on the ultrastructure of rabbit corneal endothelium (author's transl)]. | a series of rabbit corneae was preserved at -196 degrees c in liquid nitrogen using five different cryoprotective solutions: (1) 5% dextran t 40, (2) 10% polyvinylpyrrolidone, (3) 5% dextran t 40 + 10% polyvinylpyrrolidone + dimethyl sulfoxide, (4) 25% rabbit albumin + 10% polyvinylpyrrolidone, (5) 25% rabbit albumin + dimethyl sulfoxide. after thawing the corneae, the influence of the different cryoprotective solutions on the ultrastructure of corneal endothelium was evaluated and compared with ... | 1978 | 311165 |
| effects of bacterial infection and irradiation on serum colony-stimulating factor levels in tolerant and nontolerant cf1 mice. | 1978 | 339978 | |
| qualitative study of paradoxical zone phenomenon of penicillins against 17 bacterial species of clinical importance. | using a triple agar layer technique and enzymatic inactivation of penicillin, the occurrence of a paradoxical zone phenomenon (illustrated by a typical 'target' image around the reservoir of antibiotic) was determined for several bacterial species specially chosen with regards to their taxonomic position, clinical importance and penicillin susceptibility. among gram-positive bacteria, a paradoxical zone was obtained for approximately 43% of the strains studied here (all 10 strains of staphylococ ... | 1978 | 340171 |
| [development of haemophilus influenzae in culture media]. | 1978 | 315604 | |
| on the nature of nontypable haemophilus influenzae. | 193 haemophilus cultures, including 71 nontypable h. influenzae isolates, were examined with respect to phage hp1 sensitivity, lysogeny for this and for other phages and for excretion of bacteriocins. fifty of the 71 nontypable cultures were sensitive to phage hp1 but only three produced plaques. the other 47 isolates were thus probably not non-encapsulated derivatives of h. influenzae serotypes a, b, d, and e, which have discrete and characteristic phage hp1 restriction and modification systems ... | 1978 | 313183 |
| [antibacterial effect of silver nitrate and "hexargin"]. | 1978 | 416309 | |
| penicillin resistant gonorrhea discovered in allegheny county. | 1978 | 416411 | |
| rapid diagnosis of gram-negative bacterial meningitis by the limulus endotoxin assay. | the limulus amoebocyte lysate endotoxin assay was evaluated as a method for rapid diagnosis of acute bacterial meningitis in a series of 305 patients. the results of limulus assays on cerebrospinal fluid (csf) samples from these patients were compared with the results for each patient of routine bacterial cultures and gram stains. positive limulus tests were obtained on initial csf specimens from 84% of patients with culture-proven bacterial meningitis, including all patients with meningitis due ... | 1978 | 624769 |
| periorbital and orbital cellulitis in children. | the clinical and laboratory data on 87 cases of orbital and periorbital cellulitis were reviewed. two distinct clinical presentations were encountered. one group of 45 patients had no history of trauma or apparent focus of infection. blood cultures on these patients were positive in 34%. haemophilus influenzae accounted for 82% of the positive blood cultures. this group of patients shares common features with children who have facial cellulitis due to h. influenzae type b. the second group cons ... | 1978 | 634683 |
| auditory function after haemophilus influenczae meningitis. | eighty-three children, having recovered from haemophilus influenzae meningitis, were examined with audiometrical tests. fifteen of the children (18.1%) had significant hearing loss. bilateral severe hearing loss was found in 3 patients. three patients had severe hearing loss affecting one ear and slight or moderate hearing loss affecting the contralateral ear. six children had entirely unilateral severe hearing loss. bilateral or unilateral slight or moderate hearing loss was found in 3 patients ... | 1978 | 636872 |
| cephalosporin antibiotics in therapy of experimental streptococcus pneumoniae and haemophilus influenzae meningitis in rabbits. | six cephalosporin antibiotics (cefamandole, cefazolin, cephacetrile, cephalothin, cephaloridine, and cephradine) and two penicillin (ampicillin and penicillin g) were evaluated in vitro and in a rabbit model of experimental meningitis due to haemophilus influenzae or streptococcus pneumoniae. the percentage penetration ([concentration in cerebrospinal fluid/concentration in serum] x 100%) of these antibiotics varied from 0.7% for cephalothin to 17% for cephaloridine. the penetration varied inver ... | 1978 | 649999 |
| the critical role of iron in host-bacterial interactions. | the ability of potential pathogens to acquire iron in a host is an important determinant of both their virulence and the nature of the infection produced. virulent gram-negative bacteria are capable of acquiring sufficient iron from the host because their virulence (for chick embryos) is unaffected by exogenous iron. avirulent mutants which are apparently limited in their ability to acquire iron could be isolated from the virulent strains. the lethality of these mutants was significantly enhance ... | 1978 | 659605 |
| pyogenic meningitis in ibadan, nigeria. a 15-month prospective study. | between january 1976 and march 1977, cerebrospinal fluid samples from 2130 patients at university college hospital, ibadan, nigeria were examined, 130 patients were shown to have pyogenic meningitis. the commonest causative bacteria were streptococcus pneumoniae (53.8%), haemophilus influenzae (23%), neisseria meningitidis (7.7%) and klebsiella spp. (3%). most of the infections occurred in very young children: 47% of all patients were under 1 year of age, and 69% were under 5 years old. the over ... | 1978 | 675164 |
| the spectrum of infection and sensitivity of organisms isolated from african and indian children in a durban hospital. | a prospective study was undertaken over a period of six months to determine the spectrum of infection, sensitivity of organisms isolated, and suitability of antibiotics chosen in 520 consecutive patients admitted to a paediatric unit. culture and sensitivity of stool, urine and blood yielded 752 isolates; in 147 cases, more than one pathogen was isolated from the same or different sites. high rates of resistance to chloramphenicol, ampicillin, and kanamycin were seen in salmonellae other than sa ... | 1978 | 705838 |
| [antimicrobial treatment of meningitis in children: problems raised by haemophilus influenzae]. | 1978 | 709395 | |
| cephamycin derivatives: comparison of the in vitro and in vivo antibacterial activities of sq 14,359, cs-1170, and cefoxitin. | sq 14,359 is a new cephamycin-type (7alpha-och3) antibiotic belonging to a series containing a 7alpha-ureidoacetyl substituent. the compound is the most potent extended spectrum derivative of this type yet reported, surpassing cs-1170 and cefoxitin by a wide margin. this activity in vitro which extends throughout the enterobacteriaceae is particularly prominent against gram-negative organisms that are producers of "cephalosporinase-type" beta-lactamases such as enterobacter, serratia, citrobacte ... | 1978 | 711611 |
| violaceous discoloration in pneumococcal cellulitis. | two patients with periobital cellulitis, one of whom also had buccal cellulitis, had violaceous discoloration of the skin. blood cultures from both patients yielded streptococcus pneumoniae. therefore, pneumococci should be considered, in addition to haemophilus influenzae, as possible causes of cellulitis with violaceous or bluish-red discoloration. | 1978 | 714580 |
| sce-963, a new broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities. | sce-963 {7beta-[2-(2-aminothiazol-4-yl)acetamido]-3-[({1-(2-dimethylaminoethyl)- 1h-tetrazol-5-yl}thio)methyl]-ceph-3-em-4-carboxylic acid}, a new semisynthetic cephalosporin, showed excellent antibacterial activity against gram-positive and gram-negative bacteria, including haemophilus influenzae, indole-positive proteus, enterobacter species, and citrobacter freundii. the minimum inhibitory concentrations of sce-963 against most strains of clinically isolated escherichia coli, klebsiella pneum ... | 1978 | 718154 |
| bacterial infections, sensitivity patterns, and chemotherapy among hospital patients in the tropics. | a prospective clinical and bacteriological review of the pattern of bacterial infections and chemotherapy among 1931 patients admitted to university college hospital, ibadan, between july and september, 1976, showed that 394 patients (20%) had bacterial infections, but 940 patients (49%) received antimicrobial chemotherapy. thus 58% of the patients were treated either prophylactically or without bacteriological confirmation of infection. infections of the respiratory tract were commonest (28%), ... | 1978 | 725540 |
| latex agglutination, counterimmunoelectrophoresis, and protein a co-agglutination in diagnosis of bacterial meningitis. | specimens of cerebrospinal fluid from 201 patients with meningitis caused by neisseria meningitidis groups a/b/c/135, streptococcus pneumoniae (23 types), and haemophilus influenzae type b were tested for the presence of specific bacterial antigens by latex agglutination, counterimmunoelectrophoresis (cie), and protein a co-agglutination. specific antigens were found in 75% of the specimens by latex agglutination and cie, and in 60% of the specimens by protein a co-agglutination. non-specific re ... | 1978 | 748387 |
| [on the phenotypical characteristics of haemophilus isolates from human respiratory tract (author's transl)]. | 50 strains of hemophilic bacteria from the human upper respiratory tract were studied using morphological, physiological, and biochemical features including respiratory quinones. the isolates were associated with the conventional species haemophilus influenzae, h. parainfluenzae and h. aegyptius. they were grouped into the proposed biovarieties of the influenzae- and parainfluenzae-groups according to kilian's classification. the heterogeneous group of aegyptius-strains was not classified in det ... | 1978 | 749417 |
| activation of the alternate complement pathway by peptidoglycan from streptococcal cell wall. | activation of the alternate complement pathway in human serum by several bacterial components was compared. peptidoglycan from group a streptococcal cell walls was the most active material, on a weight basis, followed by cell walls, protoplast membranes, and whole cells. the group-specific carbohydrate was inactive. treatment of peptidoglycan with low concentrations of lysozyme or short periods of sonic treatment enhanced complement activation. high concentrations of lysozyme or extended sonic t ... | 1978 | 415005 |
| spread of r-factors outside the enterobacteriaceae. | 1978 | 415035 | |
| a serological survey of accredited breeding colonies in the united kingdom for common rodent viruses. | this paper reports the results of a general survey, the first in the united kingdom, carried out on accredited breeding colonies of mice, rats and guinea-pigs over a period of a year. while the results show the potential usefulness of a viral accreditation grading scheme, they also show that contamination of breeding colonies with inapparent viral infections is widespread. this situation can only be improved by the continuous monitoring of animal stocks for rodent viruses, with the aim of improv ... | 1978 | 415178 |
| endogenous prostaglandin e and contractile activity of isolated ileal smooth muscle. | the effects of endogenous prostaglandin e (pge) on the contractile activity of isolated cat ileal muscle rings were studied. force development in circularly oriented muscle fibers were recorded. the muscles contained a mean basal pge concentration of 1 +/- 0.6 ng pge per g wet wt (mean +/- se) as measured by radioimmunoassay. acetylcholine (ach) or elevated potassium caused contractions and enhanced pge concentration (p less than 0.05). removing ca2+ from high potassium solutions blocked contrac ... | 1978 | 414630 |
| clavulanic acid, a novel inhibitor of beta-lactamases. | clavulanic acid, z-(2r,5r)-3-(beta-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0] heptane-2-carboxylic acid, has been shown to be an effective inhibitor of the beta-lactamases of the richmond types ii, iii, iv, and v. inhibition is a time-dependent reaction and is irreversible. clavulanic acid had poor antibacterial activity against staphylococcus aureus, enterobacteriaceae, and pseudomonas aeruginosa, with minimal inhibitory levels greater than 25 mug/ml. it did inhibit the majority of nei ... | 1978 | 310279 |
| minimum bactericidal concentration of sulfamethoxazole-trimethoprim for haemophilus influenzae: correlation with prophylaxis. | the inability of sulfamethoxazole-trimethoprim (sxt) to eradicate haemophilus influenzae nasopharyngeal carriage in all asymptomatic patients in closed populations was examined in vitro. a broth medium was adapted for susceptibility testing of h. influenzae which permitted us to determine minimum inhibitory concentrations and minimum bactericidal concentrations (mbcs). the minimum inhibitory concentrations were all low, but the mbcs were bimodally distributed. trimethoprim alone or the combinati ... | 1978 | 310281 |
| adult haemophilus influenzae type b vertebral osteomyelitis: a case report and review of the literature. | osteomyelitis in adults due to haemophilus influenzae is exceedingly rare. we report a case of h. influenzae type b vertebral osteomyelitis in an adult. review of the english literature reveals one other adult patient with h. influenzae osteomyelitis, and sporadic pediatric cases. although a variety of predisposing host resistance factors have been postulated to account for this infection, the deficiency responsible for adult infection remains undelineated. bone biopsy is mandatory for diagnosis ... | 1978 | 310376 |
| enzyme-linked immunosorbent assay for detection and quantitation of capsular antigen of haemophilus influenzae type b. | an enzyme-linked immunosorbent assay was developed to detect the presence of the ribose-ribitol phosphate capsular antigen of haemophilus influenzae type b in laboratory and clinical specimens. the assay is simple, sensitive, specific, and quantitative and should prove to be of value in the diagnosis and management of h. influenzae infections. | 1978 | 310425 |
| [haemophilus influenzae antibodies in the body fluid]. | 1978 | 310481 | |
| the role of pre-replication and post-replication processes in mutation induction in haemophilus influenzae by n-methyl-n'-nitro-n-nitrosoguanidine. | studies were carried out on the repair and fixation of premutational damage induced in haemophilus influenzae by n-methyl-n'-nitro-n-nitrosoguanidine (mnng). the studies employed a temperature-sensitive dna elongation mutant (dna9) and its combinations with mutants defective in pyrimidine dimer excision (uvr1, uvr2) and in recombination (rec1). the dna9 mutant is shown to be leaky, allowing about 1% of the normal rate of dna synthesis at the restrictive temperature. repair of premutational lesio ... | 1978 | 310510 |
| clinical implications of preseptal (periorbital) cellulitis in childhood. | the available hospital records of all pediatric patients diagnosed as having periorbital, preseptal or orbital cellulitis over a five-year period were reviewed and compared to previously reported series. only two of 39 patients had orbital cellulitis. the 37 patients with preseptal cellulitis had two characteristic clinical presentations. twenty-two children had local trauma, abscesses, insect bites, or impetigo as the inciting event for their cellulitis. infection was usually caused by staphylo ... | 1978 | 310537 |
| meningitis due to haemophilus influenzae other than type b: case report and review. | a 4-month-old female infant with meningitis caused by haemophilus influenzae type f had a hospital course complicated by sterile subdural effusions and persistent neurologic abnormalities. one year later she was normal in all respects. the infant's mother had serum bactericidal antibodies to h. influenzae type b but not to type f. during recovery the patient had no bactericidal antibodies to type b, and the type f organism could not be maintained in her serum. review of the literature identified ... | 1978 | 310538 |
| occurrence of haemophilus epiglottitis. | 1978 | 306191 | |
| haemophilus influenzae type b infections. | 1978 | 306192 | |
| haemophilus influenzae type b osteomyelitis. | three children had osteomyelitis due to haemophilus influenzae type b. they were seen with signs and symptoms indistinguishable from infection caused by other organisms. one child was initially misdiagnosed as having septic arthritis because of failure to appreciate that hemophilus may also cause bone infection. in the second patient osteomyelitis and arthritis developed during ampicillin sodium therapy for treatment of hemophilus meningitis. his initial infection was caused by an ampicillin-sen ... | 1978 | 306193 |
| acidometric agar plate method for ampicillin susceptibility testing of haemophilus influenzae. | the need for an accurate and rapid method of testing ampicillin susceptibility of haemophilus influenzae, especially strains isolated from patients with meningitis and septicemia, is indisputable. various methods have been employed for this purpose. each has advantages and disadvantages. this report describes a modification of the capillary acidometric procedure in which an agar plate is substituted for a tube. all beta-lactamase results obtained by this modified technique correlated with minima ... | 1978 | 306220 |
| comparative activities of selected beta-lactam antibiotics against haemophilus influenzae. | the comparative activities of ampicillin, cefamandole, cefoxitin, cefaclor, and cefatrizine against both beta-lactamase-producing and non-beta-lactamase-producing isolates of haemophilus influenzae were determined by using an agar dilution susceptibility test procedure. ampicillin was the most active drug tested against non-beta-lactamase-producing isolates, whereas cefamandole was most active against beta-lactamase-producing strains. | 1978 | 306221 |
| haemophilus influenzae type b pneumonia. | thirteen patients with haemophilus influenzae type b pneumonia are reported to emphasise the clinical, radiographic, and therapeutic aspects of this illness. all but one patient was under 2 1/2 years of age. the presenting complaint was a variable duration of upper respiratory infection and fever in most cases. one-third of patients had radiographic evidence of pleural involvement; one-third showed a patchy bronchopneumonia on roentgenogram; and the remainder had segmental or lobar infiltrates. ... | 1978 | 306225 |
| bacterial infections in pediatric hodgkin's disease: relationship to radiotherapy, chemotherapy and splenectomy. | the occurrence of bacterial infections (b.i.) among 181 children with hodgkin's disease (121 with splenectomy, 60 without splenectomy) was analyzed. twenty-seven b.i. occurred among 22 children and included 15 episodes of bacteremia-meningitis in 14 children. b.i. occurred in all age groups, but bacteremia-meningitis occurred most commonly in splenectomized children 10 years of age or less. the frequency of b.i. in splenectomized children receiving radiotherapy was 1.4%, compared to 18.3% among ... | 1978 | 306282 |
| ampicillin resistance in haemophilus influenzae. | 1978 | 306385 | |
| clinical and laboratory evaluation of cefamandole in infants and children. | fifty-three infants and children, aged three months to 15 years, were treated with an average daily dose of 100 mg of cefamandole/kg intravenously. of these patients, 47 had soft tissue cellulitis and six had pneumonia. primary pathogens, including staphylococcus aureus, streptococcus pyogenes, streptococcus pneumoniae, and haemophilus influenzae, were isolated from 43 of the 53 patients. bacteremia was documented in six of the 53 patients. a satisfactory clinical and bacteriologic response to c ... | 1978 | 306402 |
| failure of cefamandole in treatment of meningitis due to haemophilus influenzae type b. | the in vitro activity of cefamandole was determined against 58 isolates of haemophilus influenzae type b; 47 were beta-lactamase-negative (ampicillin-susceptible), and 11 produced beta-lactamase (ampicillin-resistant). ampicillin-susceptible strains were susceptible to cefamandole with a median minimal bactericidal concentration (mbc) of 0.4 microgram/ml. ampicillin-resistant strains had a median mbc of 0.8 microgram/ml. prior studies have documented these concentrations of cefamandole in cerebr ... | 1978 | 306403 |
| rapid diagnosis of hemophilus influenzae type b infections by latex particle agglutination and counterimmunoelectrophoresis. | latex particle agglutination and counterimmunoelectrophoresis techniques were compared in a clinical trial to demonstrate their sensitivity, specificity, and usefulness in the rapid diagnosis of invasive hemophilus influenzae type b disease. lpa, a simplified lpa performed by house officers, and cie used in this study detected 0.2, 0.5, and 1 to 10 ng/ml of hib capsular antigen, respectively. one hundred-six illnesses suspected of being caused by hib were evaluated prospectively by these assays. ... | 1978 | 306427 |
| haemophilus influenzae bacteremia and meningitis resulting from survival of a single organism. | infant rats were infected intranasally with mixtures of streptomycin-sensitive and streptomycin-resistant strains of haemophilus influenzae type b and cultures of nasopharyngeal washings, blood, and cerebrospinal fluid were obtained. if the infecting organisms cooperated with each other during the establishment of infection, nasopharyngeal, blood, and cerebrospinal fluid cultures should have contained mixtures of the variants. if each organism acted independently, then with small infecting inocu ... | 1978 | 306628 |
| hearing disorders after haemophilus influenzae meningitis. comparison of different drug regimens. | of 131 children with bacteriologically verified haemophilus influenzae meningitis, 75 were treated with ampicillin sodium and 45 with a combination of chloramphenicol, sulfonamides, and penicillin g sodium during the first 72 hours. audiological and neuro-otologic examinations performed 1 to 15 years later showed that 3 patients were totally deaf, 11 had moderate and 15 minimal hearing losses, and 6 had vestibular disorders. all three deaf children and all those with recognized vestibular disord ... | 1978 | 306816 |
| [infectious resistance to antibiotics in haemophilus influenzae (author's transl)]. | ampicillin-resistant haemophilus influenzae does occur now in the frg. in one isolate a plasmid with resistance genes (r-factor) could be demonstrated as cause of the ampicillin resistance. this r-factor influences production of a beta-lactamase of the tem type which destroys ampicillin. the infectious nature of the ampicillin resistance was proven by the fact that it was transferable to other bacterial species through cocultivation. parallel to ampicillin resistance tetracycline resistant haemo ... | 1978 | 305840 |
| para-aminobenzoic acid. | 1978 | 305886 | |
| a dnase for apurinic/apyrimidinic sites associated with exonuclease iii of hemophilus influenzae. | an endonuclease purified from hemophilus influenzae made single strand breaks in dna containing apurinic or apyrimidinic sites but had no detectable endonuclease activity on untreated native dna. the new 5'-termini created at the cleavage sites were base-free deoxyribose 5-phosphate residues. the enzyme preparation also catalyzed the exonucleolytic release of 5'-mononucleotides from bihelical dna and the hydrolysis of dna 3'-terminal phosphomonoesters. the phosphatase-exonuclease activity was in ... | 1978 | 305919 |
| purification of specific precipitinogen and extraction of endotoxin from haemophilus influenzae. | after purifying a haemophilus influenzae precipitinogen from endotoxic activity by means of ultracentrifugation, column chromatography (sepharose 6b) and ion exchange chromatography (deae sephadex a25) a fraction was obtained which still contained a specific precipitinogen that was virtually free of endotoxin. furthermore, during the chromatographic procedures fractions with a high and a low molecular weight endotoxic activity were found. the limulus lysate test was more sensitive in the high mo ... | 1978 | 305926 |
| evidence against the reversion of mutation in the haemophilus influenzae phage hp1c1 by preinfection treatment of host cells or phage with mnng. | n-methyl-n'-nitrosoguanidine (mnng) causes reversion of a temperature-sensitive mutation in a bacteriophage of haemophilus influenzae if exposure to the mutagen takes place after infection but before lysis. however, neither pre-infection treatment of the phage dna, host cells, or both will cause reversion. the reasons for this are discussed in relation to the somewhat different results in the escherichia coli lambda phage system and in relation to error-prone repair and replication processes. | 1978 | 306062 |
| hip joint infections in infants and children. | 1978 | 306087 | |
| effect of ampicillin and chloramphenicol against haemophilus influenzae. | synergy, determined by isobolograms constructed from the minimal inhibitory concentrations of combinations of ampicillin and chloramphenicol, was observed against six of 13 ampicillin-susceptible haemophilus influenzae type b isolates and against five of eight ampicillin-resistant strains by using a small inoculum of 10(4) colony forming units (cfu) per milliliter. synergy occurred against nine of 13 ampicillin-susceptible and against two of eight ampicillin-resistant strains using a large inocu ... | 1978 | 306090 |
| radiometric detection of haemophilus influenzae in cerebrospinal fluid specimens. | the investigation demonstrates the usefulness of a radiometric urease test in the rapid detection of haemophilus influenzae in cerebrospinal fluid specimens. the test is simple and economical to perform and results are obtained within a one hour incubation period. | 1978 | 305614 |
| [a study on periodontal dressing materials. part 7. the effects of liquid of periodontal dressing materials on the capillary permeability of subcutaneous tissue of rabbit (author's transl)]. | 1978 | 296221 | |
| [changes in bovine mandible during fetal development; combined microradiographic, x-ray diffractometric and thermogravimetric investigation]. | 1978 | 296266 | |
| ampicillin-resistant hemophilus influenzae. | ampicillin-resistant hemophilus influenzae had not been identified in fresno, california, before june 1976. in the 12 months that followed, eight resistant type b strains and three resistant nontypable isolates were cultured from patients treated at two hospitals that provide nearly all of the acute pediatric inpatient care for the area. two of the resistant strains were obtained from patients with invasive infections and represented 4.2 percent of hemophilus influenzae isolated from blood, cere ... | 1978 | 305157 |
| meningitis due to chloramphenicol-resistant haemophilus influenzae type b. | 1978 | 305271 | |
| mapping of the single cleavage site in s13 replicative form dna of hemophilus influenzae (hind iii) restriction enzyme. | 1978 | 304632 | |
| hemophilus influenzae pneumonia in adults. | hemophilus influenzae pneumonia was diagnosed in 41 adult patients based on cultures of blood, pleural fluid or transtracheal aspirate. bacteremia occurred in all age groups, but was most frequent in patients over the age of 50 years with severe underlying pulmonary disease. chest films usually demonstrated multisegmental or multilobar infiltrates without evidence of cavitation. pleural involvement was evident in half of the patients, although empyema occurred infrequently. mortality was almost ... | 1978 | 304671 |
| comparison of rapid methods of antimicrobial susceptibility in haemophilus influenzae. | a method is described for the rapid, simultaneous determination of the mic's of chloramphenicol and ampicillin to haemophilus influenzae. excellent agreement was observed between the autobac method and the agar dilution method for antimicrobial susceptibility. all ampicillin resistant haemophilus isolates produced beta lactamase and none of the suceptible strains produced this enzyme. | 1978 | 304695 |
| characterization of the immunoprotective antigen of ribosomal preparations from haemophilus influenzae. | this investigation was designed to characterize the immunoprotective antigen of ribosomal preparations from haemophilus influenzae. the ribosomes that elicited 80 to 90% protection contained 25% protein and 75% ribonucleic acid but did not contain any detectable hexoses. the immunodiffusion and hemagglutination inhibition tests also failed to demonstrate that the capsular material (polyribose phosphate) was in ribosomal preparations. treatment of ribosomes with ribonuclease degraded 78% ribonucl ... | 1978 | 304844 |
| bacteremia associated with haemophilus influenzae type e biotype 4. | haemophilus influenzae type e biotype 4 was isolated from a single antemortem blood culture obtained from a 60-year-old, white male with abdominal carcinomatosis. | 1978 | 304860 |
| detection of capsulated haemophilus influenzae in chest infections by counter current immunoelectrophoresis. | the application of counter current immunoelectrophoresis to the detection of haemophilus influenzae capsular antigen in sputum is described. the method, technically simple, provided results within 30 minutes. h. influenzae capsular antigen was detected in 12% of patients and in 54.8% of the h. influenzae strains isolated. the test was not impaired by prior antibiotic therapy. | 1978 | 304861 |
| development of ampicillin-resistance during treatment of haemophilus influenzae pneumonia. | 1978 | 304475 | |
| an improved method for detection of hemophilus influenzae b antigen in cerebrospinal fluid. | 1978 | 304476 | |
| ampicillin-resistant followed by ampicillin-sensitive hemophilus influenzae meningitis in a normal host. | 1978 | 304477 | |
| resistance of h. influenzae to ampicillin. | 1978 | 304479 | |
| acute epiglottitis and systemic infection with hemophilus influenzae. | 1978 | 304374 | |
| cell-mediated immune response to dog pulp tissue altered by eugenol within the root canal. | after pulpal extirpation of twenty teeth in each of four dogs, these animals were primarily immunized intramuscularly with the dog's own pulp (three dogs) and saline solution with pulp (one dog). a fifth dog was used as a control for skin tests. secondary immunizations were accomplished via the root canal every 7 days over a 28-day period. cell-mediated skin-test reactions demonstrated less of a response to the eugenol alone than when the dog's pulp was incubated with this material. in vitro ana ... | 1978 | 273194 |
| modification of "c" synapses following partial central deafferentation of thoracic motoneurones. | 1978 | 273463 | |
| evolutionary adaptation of membranes to temperature. | the "fluidity" of brain synaptosomal membrane preparations of arctic and hot-springs fish species, two temperature water fish species acclimated to different seasonal temperatures, and two mammals was estimated using the fluorescence polarization technique. at all measurement temperatures, the fluidity decreased in the order: arctic sculpin, 5 degrees-acclimated goldfish, 25 degrees-acclimated goldfish, desert pupfish, and rat. this correlated with increasing adaptation or body (i.e., cellular) ... | 1978 | 273929 |
| localization of eukaryotic initiation factor 3 on native small ribosomal subunits. | the localization of eukaryotic initiation factor 3(eif-3) on native small ribosomal subunits has been established by electron microscopy through a comparison of native small ribosomal subunits with derived subunits and with native subunits stripped of eif-3. small subunits derived from reticulocyte ribosomes by the puromycin/kcl method are seen in electron micrographs as elongated particles, divided by a heavily stained partition into approximately one-third and two-third domains. most particles ... | 1978 | 274727 |
| [periodontal treatment in general dental practice with emphasis on rational and effective working methods]. | 1978 | 274845 | |
| [total replacement of the temporomandibular joint by means of alloplastic materials. i]. | 1978 | 274848 |