Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| update: severe acute respiratory syndrome--united states, may 21, 2003. | cdc continues to work with state and local health departments, the world health organization (who), and other partners to investigate cases of severe acute respiratory syndrome (sars). this report updates sars cases reported worldwide and in the united states and highlights recent modifications to the u.s. sars case definition that define criteria for exclusion of previously reported sars cases and for reporting travel-associated cases of sars. | 2003 | 12807079 |
| cluster of severe acute respiratory syndrome cases among protected health-care workers--toronto, canada, april 2003. | infections among health-care workers (hcws) have been a common feature of severe acute respiratory syndrome (sars) since its emergence. the majority of these infections have occurred in locations where infection-control precautions either had not been instituted or had been instituted but were not followed. recommended infection-control precautions include the use of negative-pressure isolation rooms where available; n95 or higher level of respiratory protection; gloves, gowns, and eye protectio ... | 2003 | 12807083 |
| update: severe acute respiratory syndrome--united states, may 14, 2003. | cdc continues to work with state and local health departments, the world health organization (who), and other partners to investigate cases of severe acute respiratory syndrome (sars). this report provides an update on reported sars cases worldwide and in the united states. | 2003 | 12807084 |
| severe acute respiratory syndrome--singapore, 2003. | the singapore ministry of health (moh), with assistance from the world health organization (who), has been investigating an outbreak of severe acute respiratory syndrome (sars). this is a novel condition caused by the sars-associated coronavirus (sars-cov) and is characterized by both an atypical pneumonia and efficient nosocomial transmission. this report summarizes epidemiologic features of this outbreak in singapore, including the influence of super spreaders and the national prevention and c ... | 2003 | 12807088 |
| update: severe acute respiratory syndrome--united states, 2003. | cdc, in collaboration with state and local health departments, the world health organization (who), and other partners, continues to investigate cases of severe acute respiratory syndrome (sars). during november 1, 2002-may 7, 2003, a total of 6,903 sars cases were reported to who from 29 countries, including the united states; 495 deaths (case-fatality proportion: 7.2%) have been reported. this report updates information on reported u.s. sars cases. | 2003 | 12807089 |
| a new infectious disease challenge: urbani severe acute respiratory syndrome (sars) associated coronavirus. | 2003 | 12807475 | |
| lessons learned. | 2003 | 12808698 | |
| update: severe acute respiratory syndrome--united states, may 28, 2003. | cdc continues to work with state and local health departments, the world health organization (who), and other partners to investigate cases of severe acute respiratory syndrome (sars). this report updates sars cases reported worldwide and in the united states and reports a seventh laboratory-confirmed u.s. case. | 2003 | 12809112 |
| mrna cap-1 methyltransferase in the sars genome. | the 3d jury system has predicted the methyltransferase fold for the nsp13 protein of the sars coronavirus. based on the conservation of a characteristic tetrad of residues, the mrna cap-1 methyltransferase function has been assigned to this protein, which has potential implications for antiviral therapy. | 2003 | 12809601 |
| sars: at least and at last, are we learning from the worst? | 2003 | 12809801 | |
| [severe acute respiratory syndrome (sars)]. | severe acute respiratory syndrome (sars) is a viral disease, observed primarily in southern china in november 2002, with variable flu-like symptoms and pneumonia, in approx. 5% leading to death from respiratory distress syndrome (rds). the disease was spread over more than 30 states all over the globe by sars-virus-infected travelers. who and cdc received first information about a new syndrome by the end of february 2003, after the first cases outside the republic of china had been observed. a c ... | 2003 | 12811416 |
| [severe acute respiratory syndrome (sars)]. | the severe acute respiratory syndrome (sars) is a highly infectious respiratory disease, to the best of our knowledge caused by a hitherto unknown corona virus. the virus has spread from south east asia to many countries of the world. three case reports of patients from the prince of wales hospital of the chinese university of hong kong demonstrate typical clinical courses. fever, cough, in most cases non-productive, myalgia, chills, and rigor are the leading symptoms. leucopenia and thrombocyto ... | 2003 | 12813666 |
| [sars--the facts. transmission, diagnosis and managing suspected cases]. | severe acute respiratory syndrome (sars) is a new infectious disease that, in the short period between 1 february and 24 april 2003, has been diagnosed in more than 4000 patients. its origin was traced to guandong, a province in southeast china. the culprit organism was identified as a new coronavirus. the clinical presentation is unspecific and includes fever, respiratory symptoms, lymphopenia and pulmonary infiltrates on x-ray. essential steps to prevent further dissemination of the virus are ... | 2003 | 12813976 |
| severe acute respiratory syndrome coronavirus and viral mimicry. | 2003 | 12814734 | |
| china and germany join forces over sars. | 2003 | 12815391 | |
| update: severe acute respiratory syndrome--united states, june 18, 2003. | cdc continues to work with state and local health departments, the world health organization (who), and other partners to investigate cases of severe acute respiratory syndrome (sars). this report updates reported sars cases worldwide and in the united states and summarizes changes in travel recommendations for provinces in china with the exclusion of beijing, where a travel advisory remains. | 2003 | 12816108 |
| sars wars: confronting a new microbe. | 2003 | 12818820 | |
| from the centers for disease control and prevention. severe acute respiratory syndrome--singapore, 2003. | 2003 | 12824198 | |
| from the centers for disease control and prevention. update: severe acute respiratory syndrome--united states, may 28, 2003. | 2003 | 12824199 | |
| severe acute respiratory syndrome. | the mysterious severe acute respiratory syndrome (sars) that has originated from the southern chinese province of guangdong appears to be a major public health threat and medical challenge. laboratory studies of sars patients in a number of countries identified the etiologic agent being a novel member of coronaviridae. high rna concentrations of this virus in sputum make it as a highly infectious agent. low concentrations of viral genome are also detectable in feces. coronaviruses are ubiquitos. ... | 2003 | 12824956 |
| pentoxifylline and severe acute respiratory syndrome (sars): a drug to be considered. | the recent outbreak of severe acute respiratory syndrome (sars) as a new viral disease is causing a great concern for health authorities and general population. very little is known about the infectious agent (a coronavirus) and its etiopathogeny, having no specific treatment yet. proinflammatory cytokines released by stimulated macrophages in the alveoli could have a prominent role in pathogenesis of sars. current treatment of sars with antiviral agents such as ribavirin and corticosteroids hav ... | 2003 | 12824965 |
| [sars (severe acute respiratory syndrome). from which animal does this coronavirus originate?]. | 2003 | 12825583 | |
| [sars genome deciphered]. | 2003 | 12828178 | |
| [will a vaccine save us from sars?]. | 2003 | 12830249 | |
| [sars--the merciless test of preparedness]. | 2003 | 12830275 | |
| sars: an emerging global disease with a local impact. | 2003 | 12830677 | |
| health is a global issue. | 2003 | 12835748 | |
| sars outbreak in the philippines. | 2003 | 12836452 | |
| sars--a fast moving infectious disease. | 2003 | 12836636 | |
| [recommendations on corticosteroid therapy in patients with severe acute respiratory syndrome]. | 2003 | 12837159 | |
| [clinical investigation of outbreak of nosocomial severe acute respiratory syndrome]. | to summarize and analyze the clinical manifestation, diagnosis and therapeutic strategy of severe acute respiratory syndrome (sars), and its characteristics of outbreak in hospital via infection transmission cluster associated with sars patients. | 2003 | 12837162 |
| from the centers for disease control and prevention. update: severe acute respiratory syndrome-- united states, june 11, 2003. | 2003 | 12837704 | |
| global outbreak of severe acute respiratory syndrome (sars). | 2003 | 12839707 | |
| severe acute respiratory syndrome (sars). | several cases of life threatening respiratory disease with no identifiable cause were reported from guangdong province, china; these were soon followed by reports from many other countries. the disease was named as severe acute respiratory syndrome (sars). a novel coronavirus, isolated from the respiratory secretions of patients, has been implicated in the causation of sars. the modes of transmission include droplet spread, close contact, and fomites; shedding of virus from respiratory tract is ... | 2003 | 12841401 |
| sars: lessons learned thus far. | 2003 | 12841969 | |
| update: severe acute respiratory syndrome--united states, 2003. | cdc continues to work with state and local health departments, the world health organization (who), and other partners to investigate cases of severe acute respiratory syndrome (sars). this report updates reported sars cases worldwide and in the united states, and summarizes changes in travel recommendations for beijing and taiwan, where travel advisories have been downgraded to travel alerts. | 2003 | 12844079 |
| a new recruit for the army of the men of death. | the army of the men of death, in john bunyan's memorable phrase, has a new recruit, and fear has a new face: a face wearing a surgical mask. | 2003 | 12844350 |
| the effect of sars coronavirus on blood system: its clinical findings and the pathophysiologic hypothesis. | severe acute respiratory syndrome (sars) has recently recognized as a new human infectious disease. a novel coronavirus was identified as the causative agent of sars. this report summarizes the hematological findings in sars patients and proposes a hypothesis for the pathophysiology of sars coronavirus related abnormal hematopoiesis. hematological changes in patients with sars were common and included lymphopenia (68% - 90% of adults; 100% of children, n = 10), thrombocytopenia (20% - 45% of adu ... | 2003 | 12844398 |
| sars genome chip available to scientists: the niaid hopes that widespread access to the sars genome chip will catalyse research into effective treatments for the virus. | 2003 | 12846246 | |
| severe acute respiratory syndrome (sars). | 2003 | 12846882 | |
| severe acute respiratory syndrome. | 2003 | 12847831 | |
| [study on the epidemiological characteristics of severe acute respiratory syndrome in shanxi province]. | to describe the epidemiological characteristics and related factors of sars in shanxi in order to provide scientific basis for prevention and control of severe acute respiratory syndrome (sars). | 2003 | 12848908 |
| [the application of indirect immuno-fluorescence assay in the diagnosis of severe acute respiratory syndrome]. | to explore the temporal profile of serum antibody against coronavirus in patients with severe acute respiratory syndrome (sars), and to evaluate the reliability of indirect immuno-fluorescence assay (ifa) in the diagnosis of sars. | 2003 | 12848915 |
| coronavirus genomic-sequence variations and the epidemiology of the severe acute respiratory syndrome. | 2003 | 12853594 | |
| sars: what have we learned? | 2003 | 12853923 | |
| zcurve_cov: a new system to recognize protein coding genes in coronavirus genomes, and its applications in analyzing sars-cov genomes. | a new system to recognize protein coding genes in the coronavirus genomes, specially suitable for the sars-cov genomes, has been proposed in this paper. compared with some existing systems, the new program package has the merits of simplicity, high accuracy, reliability, and quickness. the system zcurve_cov has been run for each of the 11 newly sequenced sars-cov genomes. consequently, six genomes not annotated previously have been annotated, and some problems of previous annotations in the rema ... | 2003 | 12859968 |
| identification of an epitope of sars-coronavirus nucleocapsid protein. | the nucleocapsid (n) protein of severe acute respiratory syndrome-coronavirus (sars-cov) is a major virion structural protein. in this study, two epitopes (n1 and n2) of the n protein of sars-cov were predicted by bioinformatics analysis. after immunization with two peptides, the peptides-specific antibodies were isolated from the immunized rabbits. the further experiments demonstrated that n1 peptide-induced polyclonal antibodies had a high affinity to bind to e. coli expressed n protein of sar ... | 2003 | 12862314 |
| [antibody response of patients with severe acute respiratory syndrome (sars) to nucleocapsid antigen of sars-associated coronavirus]. | to assess serum antibody responses of patients with severe acute respiratory syndrome (sars) to nucleocapsid (n) antigen of sars-associated coronavirus. | 2003 | 12865207 |
| rapid and efficient preparation of monoclonal antibodies against sars-associated coronavirus nucleocapsid protein by immunizing mice. | to develop a rapid and efficient method for preparing monoclonal antibodies (mab) against sars-associated coronavirus (sars-cov) nucleocapsid (n) protein. | 2003 | 12865208 |
| severe acute respiratory syndrome (sars): breath-taking progress. | reports of a new severe respiratory disease, now defined as severe acute respiratory syndrome (sars), began to emerge from guangdong, in southern china, in late 2002. the condition came to international attention through an explosive outbreak in hong kong in march 2003. cases appeared throughout south-east asia and in toronto, the spread of sars being accelerated by international air travel. a global emergency was declared by the world health organization, bringing together an international team ... | 2003 | 12867552 |
| description and clinical treatment of an early outbreak of severe acute respiratory syndrome (sars) in guangzhou, pr china. | severe acute respiratory syndrome (sars), now known to be caused by a coronavirus, probably originated in guangdong province in southern china in late 2002. the first major outbreak occurred in guangzhou, the capital of guangdong, between january and march 2003. this study reviews the clinical presentation, laboratory findings and response to four different treatment protocols. case notes and laboratory findings were analysed and outcome measures were collected prospectively. the sars outbreak i ... | 2003 | 12867568 |
| [severe acute respiratory syndrome: the first transmissible disease of the 21st century]. | the severe acute respiratory syndrome (sars) is the first severe and easily transmissible disease to emerge in the 21st century. it is caused by the infection with a coronavirus, a single strand rna capsulated virus, recently found in a small mammalian, the masked palm civet. it is likely to represent the source of human infection. the first cases of sars have been reported in the chinese province of guangdong and, since then, probable cases have been reported world wide. the clinical picture is ... | 2003 | 12868234 |
| sars in china. china's missed chance. | 2003 | 12869735 | |
| sars in china. tracking the roots of a killer. | 2003 | 12869736 | |
| sars in china. the big question now: will it be back? | 2003 | 12869737 | |
| hong kong sars sequence. | 2003 | 12869741 | |
| update: severe acute respiratory syndrome--worldwide and united states, 2003. | this report updates reported cases of severe acute respiratory syndrome (sars) worldwide and in the united states, describes a change in the recommended timing of collection of a convalescent-phase serum specimen to test for antibody to sars-associated coronavirus (sars-cov), and introduces a new case exclusion criterion based on negative sars-cov serology. in addition, this report also summarizes changes in travel alerts for beijing and mainland china, hong kong, toronto, and taiwan. | 2003 | 12869906 |
| [identification and molecular cloning and sequence analysis of a novel coronavirus from patients with sars by rt-pcr]. | to investigate the etiologic agents of the sars and develop diagnostic method for this disease. | 2003 | 12869994 |
| severe acute respiratory syndrome (sars): an interim information paper for dental health care workers. | 2003 | 12873106 | |
| the complete genome sequence of severe acute respiratory syndrome coronavirus strain hku-39849 (hk-39). | the complete genomic nucleotide sequence (29.7kb) of a hong kong severe acute respiratory syndrome (sars) coronavirus (sars-cov) strain hk-39 is determined. phylogenetic analysis of the genomic sequence reveals it to be a distinct member of the coronaviridae family. 5' race assay confirms the presence of at least six subgenomic transcripts all containing the predicted intergenic sequences. five open reading frames (orfs), namely orf1a, 1b, s, m, and n, are found to be homologues to other cov mem ... | 2003 | 12876307 |
| guest editorial. | 2003 | 12880749 | |
| [ultrastructural characteristics of sars associated virus in infected cells]. | electron microscopical study of infected cells to identify the pathogenic agent of sars. | 2003 | 12882683 |
| [gene detection of severe acute respiratory syndrome-related coronavirus]. | to develop a newly real-time rt-polymerase chain reaction assay for severe acute respiratory syndrome (sars) related coronavirus in human whole blood. | 2003 | 12882684 |
| [gene detection of severe acute respiratory syndrome-related coronavirus]. | to develop a newly real-time rt-polymerase chain reaction assay for severe acute respiratory syndrome (sars) related coronavirus in human whole blood. | 2003 | 12882684 |
| systematic, genome-wide identification of host genes affecting replication of a positive-strand rna virus. | positive-strand rna viruses are the largest virus class and include many pathogens such as hepatitis c virus and the severe acute respiratory syndrome coronavirus (sars). brome mosaic virus (bmv) is a representative positive-strand rna virus whose rna replication, gene expression, and encapsidation have been reproduced in the yeast saccharomyces cerevisiae. by using traditional yeast genetics, host genes have been identified that function in controlling bmv translation, selecting bmv rnas as rep ... | 2003 | 14671320 |
| [expression, purification and identification of recombinant sars coronavirus membrane protein]. | a novel coronavirus (sars-coronavirus, sars-cov) was discovered as the pathogen of the severe acute respiratory syndrome (sars). according to studies with other coronaviruses, the membrane protein (m protein) is the main structural protein and the recombinant m protein may be useful as an antigen for detecting antibodies against coronavirus and for preparing vaccine. in this work, the m protein of sars-cov was expressed in e. coli as fusion protein with maltose binding protein at n-terminus and ... | 2003 | 14673508 |
| the secret life of ace2 as a receptor for the sars virus. | the membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ace2) is an essential regulator of heart function. now, li at al. identify and characterize an unexpected second function of ace2 as a partner of the sars-cov spike glycoprotein in mediating virus entry and cell fusion. | 2003 | 14675530 |
| severe acute respiratory syndrome vaccine development: experiences of vaccination against avian infectious bronchitis coronavirus. | vaccines against infectious bronchitis of chickens (gallus gallus domesticus) have arguably been the most successful, and certainly the most widely used, of vaccines for diseases caused by coronaviruses, the others being against bovine, canine, feline and porcine coronaviruses. infectious bronchitis virus (ibv), together with the genetically related coronaviruses of turkey (meleagris gallopovo) and ring-necked pheasant (phasianus colchicus), is a group 3 coronavirus, severe acute respiratory syn ... | 2003 | 14676007 |
| severe acute respiratory syndrome vaccine development: experiences of vaccination against avian infectious bronchitis coronavirus. | vaccines against infectious bronchitis of chickens (gallus gallus domesticus) have arguably been the most successful, and certainly the most widely used, of vaccines for diseases caused by coronaviruses, the others being against bovine, canine, feline and porcine coronaviruses. infectious bronchitis virus (ibv), together with the genetically related coronaviruses of turkey (meleagris gallopovo) and ring-necked pheasant (phasianus colchicus), is a group 3 coronavirus, severe acute respiratory syn ... | 2003 | 14676007 |
| sars. | 2003 | 14677346 | |
| a wake-up call for our health-care system. | 2003 | 14677347 | |
| emerging viruses set to soar. | the emergence rate of novel viruses, such as the coronavirus that sparked sars, could well be on the rise. researchers now think that the sars virus split from group 2 coronaviruses, and that this happened relatively recently on the scale of coronavirus evolution. | 2003 | 14678728 |
| [epidemiological study of the features of the index cases in sars case clusters]. | to understand the epidemiological characteristics of the index cases in severe acute respiratory syndrome (sars) cases clusters and to evaluate their importance in the whole epidemic process of sars. | 2003 | 14678890 |
| sars--one year later. | 2003 | 14681502 | |
| the severe acute respiratory syndrome. | 2003 | 14681510 | |
| detection of sars coronavirus in plasma by real-time rt-pcr. | 2003 | 14681520 | |
| estimated timing of the last common ancestor of the sars coronavirus. | 2003 | 14681521 | |
| [gene prediction and function research of sars-cov(bj01)]. | through reading the articles, this study points out the shortage of gene prediction and function research about sars-cov, and predict it again for developing effective drugs and future vaccines. using twelve gene prediction methods to predict coronavirus known genes, we select four better methods including heuristic models, gene identification, zcurve_cov and orf finder to predict sars-cov(bj01), and use atgpr for analyzing probability of initiation codon and kozak rule, search transcription reg ... | 2003 | 14682248 |
| breakthrough of the year. sars: a pandemic prevented. | 2003 | 14684791 | |
| china: from sars to the stars. | 2003 | 14685192 | |
| sars 3: are we ready? | 2003 | 14690300 | |
| the virus that changed my world. | 2003 | 14691538 | |
| canadian severe acute respiratory syndrome (sars) experience. | 2003 | 14694900 | |
| sars--lessons from two singapore general hospital cases. | two cases of severe acute respiratory syndrome (sars) that occurred in singapore general hospital are described. the lessons learnt are outlined. | 2003 | 14700422 |
| [clinical analysis of patients with severe acute respiratory syndrome in beijing area]. | to study the epidemiological, clinical and laboratory characteristics, treatment and prognosis of patients with severe acute respiratory syndrome (sars). | 2003 | 14703443 |
| development of a sars vaccine: an industrial perspective on the global race against a global disease. | 2003 | 14711331 | |
| [consensus of the management of severe acute respiratory syndrome]. | 2003 | 14723215 | |
| early influenza in europe and sars escaping from high security laboratories! | 2003 | 14724330 | |
| sars: retrospective cohort study among german guests of the hotel 'm', hong kong. | hong kong played a pivotal role in the international spread of the severe acute respiratory syndrome (sars): a doctor who spent the night of 21-22 february 2003 at hotel 'm' was identified as the index case for four national and international clusters of sars. in parallel to the international collaborative study led by who and united states, a retrospective study on the cohort of german persons staying at hotel 'm' was conducted. the inclusion criteria covered a period from 21 february to 3 marc ... | 2003 | 14724331 |
| asymptomatic severe acute respiratory syndrome-associated coronavirus infection. | 2003 | 14725258 | |
| [sars-associated coronavirus gene fragments were detected from a suspected pediatric sars patient]. | a special "fever and cough" clinic was set up at the children's hospital affiliated to capital institute of pediatrics for children with symptoms of fever and cough in late april when the severe acute respiratory syndrome (sars) epidemic was at its peak in beijing to separate the children with fever from others during their visit to the outpatient department. | 2003 | 14733796 |
| [clinical and chest x-ray characteristics of 5 cases with severe acute respiratory syndrome in children in shenzhen area]. | to explore clinical and chest x-ray features of sars in children to facilitate correct diagnosis. | 2003 | 14733797 |
| [clinical analysis of pediatric sars cases in beijing]. | to study clinical characteristics of pediatric sars cases in beijing. | 2003 | 14744375 |
| [the diagnosis and differential diagnosis of three suspect sars cases]. | 2003 | 14744392 | |
| [progresses in studies on sars-associated coronavirus]. | 2003 | 14744401 | |
| conference report - i. investigating new vaccines: ebola and hiv: highlights from the viral vaccine meeting; october 25-28, 2003; barcelona, spain. | 2003 | 14745371 | |
| conference report - ii. investigating new vaccines: sars. highlights from the viral vaccine meeting; october 25-28, 2003; barcelona, spain. | 2003 | 14745373 | |
| class orders now possible under ontario's public health legislation. | in april 2003, the ontario legislature amended the province's public health legislation as part of a package of amendments related to the recent outbreak of severe acute respiratory syndrome (sars). although the amendments to the health protection and promotion act (hppa) were clearly designed to address emergency situations like sars, they may have unintended and negative consequences for people living with hiv/aids. | 2003 | 14746297 |
| [pay attention to severe acute respiratory syndrome]. | 2003 | 14748986 | |
| [etiology of severe acute respiratory syndrome]. | 2003 | 14749001 |