Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| genome-wide definition of selective sweeps reveals molecular evidence of trait-driven domestication among elite goat (capra species) breeds for the production of dairy, cashmere, and meat. | the domestication of wild goats and subsequent intensive trait-driven crossing, inbreeding, and selection have led to dramatic phenotypic purification and intermediate breeds for the high-quality production of dairy, cashmere wool, and meat. genomic resequencing provides a powerful means for the direct identification of trait-associated sequence variations that underlie molecular mechanisms of domestication. | 2018 | 30165633 |
| population genomics analyses of european ibex species show lower diversity and higher inbreeding in reintroduced populations. | restoration of lost species ranges to their native distribution is key for the survival of endangered species. however, reintroductions often fail and long-term genetic consequences are poorly understood. alpine ibex (capra ibex) are wild goats that recovered from <100 individuals to ~50,000 within a century by population reintroductions. we analyzed the population genomic consequences of the alpine ibex reintroduction strategy. we genotyped 101,822 genomewide single nucleotide polymorphism loci ... | 2018 | 29387150 |
| exposure to neospora spp. and besnoitia spp. in wildlife from israel. | neosporosis and besnoitiosis, caused by cyst-forming protozoa neospora caninum and besnoitia besnoiti, respectively, are parasitic infestations of livestock in israel. these parasites cause significant economic losses in cattle due to reproductive and productive disorders. both parasites have been detected in several wild ruminant species throughout other regions of the world, while the existence of a sylvatic life cycle in israel remains uncertain. thus, a wide panel of 871 sera from two wild c ... | 2018 | 30175044 |
| transmission of helminths between species of ruminants in austria appears more likely to occur than generally assumed. | helminth infections of the gastrointestinal tract and lungs can lead to devastating economical losses to the pastoral based animal production. farm animals can suffer from malnutrition, tissue damage, and blood loss resulting in impaired production traits and reproduction parameters. in austria, pastures grazed by sheep, goats, and cattle overlap with the habitats of several species of wild cervids (roe deer, red deer, sika deer, and fallow deer) and bovids (mouflon, chamois, and ibex), and tran ... | 2018 | 29662884 |
| hplc-qtof method for quantifying 11-ketoetiocholanolone, a cortisol metabolite, in ruminants' feces: optimization and validation. | studies of animal ecology can benefit from a quantified understanding of eco-physiological processes and, in particular, of the physiological responses in free-ranging animals to potential stressors. the determination of fecal cortisol metabolites as a noninvasive method for monitoring stress has proved to be a powerful tool. high-performance liquid chromatography coupled with tandem mass spectrometry (hplc-ms/ms) has emerged as the most accurate method for avoiding problems related to the nonsp ... | 2018 | 30377495 |
| the effect of male age on patterns of sexual segregation in siberian ibex. | sexual segregation is very common in sexually size dimorphic ungulates and may be the result of different habitat preferences and/or differential social behaviours of males and females. various hypotheses have been put forward to explain this phenomenon. in the present research, we examined sexual segregation in a quite poorly understood species, the siberian ibex. the species presents a marked sexual size dimorphism, with adult males weighing double as much as females. we use the sexual segrega ... | 2018 | 30166602 |
| batch effects in a multiyear sequencing study: false biological trends due to changes in read lengths. | high-throughput sequencing is a powerful tool, but suffers biases and errors that must be accounted for to prevent false biological conclusions. such errors include batch effects; technical errors only present in subsets of data due to procedural changes within a study. if overlooked and multiple batches of data are combined, spurious biological signals can arise, particularly if batches of data are correlated with biological variables. batch effects can be minimized through randomization of sam ... | 2018 | 29573184 |
| characterizing the growth of sarcoptes scabiei infrapopulations. | during the course of parasitic disease infestations, parasite population sizes change at both individual host (infrapopulation) and host population (metapopulation) levels. however, most studies only report epidemiological values for specific locations and times. in this study we analysed the dynamics of several sarcoptes scabiei infrapopulations from experimentally infested iberian ibex, capra pyrenaica. we obtained mite counts by digesting small skin biopsies, which we compared with indices ob ... | 2018 | 30155594 |
| evaluation of radiomics to predict the accuracy of markerless motion tracking of lung tumors: a preliminary study. | template-based matching algorithms are currently being considered for markerless motion tracking of lung tumors. these algorithms use tumor templates derived from the planning ct scan, and track the motion of the tumor on single energy fluoroscopic images obtained at the time of treatment. in cases where bone may obstruct the view of the tumor, dual energy fluoroscopy may be used to enhance soft tissue contrast. the goal of this study is to predict which tumors will have a high degree of accurac ... | 2018 | 30109215 |
| the role of pickup ion dynamics outside of the heliopause in the limit of weak pitch angle scattering: implications for the source of the ibex ribbon. | we present a new model of the interstellar boundary explorer (ibex) ribbon based on the secondary energetic neutral atom (ena) mechanism, under the assumption that there is negligible pitch angle scattering of pickup ions (puis) outside the heliopause. using the results of an mhd-plasma/kinetic-neutral simulation of the heliosphere, we generate puis in the outer heliosheath, solve their transport using guiding center theory, and compute ribbon ena fluxes at 1 au. we implement several aspects of ... | 2018 | 29861499 |
| variation in algorithm implementation across radiomics software. | given the increased need for consistent quantitative image analysis, variations in radiomics feature calculations due to differences in radiomics software were investigated. two in-house radiomics packages and two freely available radiomics packages, mazda and ibex, were utilized. forty 256×256-pixel regions of interest (rois) from 40 digital mammograms were studied along with 39 manually delineated rois from the head and neck (hn) computed tomography (ct) scans of 39 patients. each package was ... | 2018 | 30840747 |
| horn growth variation and hunting selection of the alpine ibex. | selective hunting can affect demographic characteristics and phenotypic traits of the targeted species. hunting systems often involve harvesting quotas based on sex, age and/or size categories to avoid selective pressure. however, it is difficult to assess whether such regulations deter hunters from targeting larger "trophy" animals with longer horns that may have evolutionary consequences. here, we compile 44,088 annually resolved and absolutely dated measurements of alpine ibex (capra ibex) ho ... | 2018 | 29676473 |
| the effect of lung consolidation, as determined by ultrasonography, on first-lactation milk production in holstein dairy calves. | bovine respiratory disease (brd) is a complex disease process and many reports emphasize the negative implications of clinical brd in dairy calves. early diagnosis can be difficult because of inconsistent or absent clinical signs; however, the use thoracic ultrasonography has the potential to improve detection of respiratory disease. earlier detection of brd may result in actions to improve calf welfare and production. the objective of this prospective cohort study was to determine if lung conso ... | 2018 | 29525311 |
| effect of two cooling protocols on the post-thaw characteristics of iberian ibex sperms. | the rate at which lethal intracellular ice forms during sperm cryopreservation is highly dependent on the cooling protocol. the present work compares two cooling protocols for use with iberian ibex (capra pyrenaica) sperm by assessing the effects on the motility, viability, and size of frozen-thawed sperm cells. ejaculates, obtained from six adult ibex males via transrectal, ultrasound-guided massage of the accessory sex glands plus electroejaculation if necessary, were cooled via either 1) prot ... | 2018 | 29352980 |
| on the possible role of ticks in the eco-epidemiology of coxiella burnetii in a mediterranean ecosystem. | ruminant livestock is the main reservoir of coxiella burnetii (cb), but little is known about the role of wildlife and ticks in its epidemiology. the iberian ibex (capra pyrenaica, schinz 1838) population of "ports de tortosa i beseit" (ne spain) suffers intense tick infestations and low reproduction rates. this study aims to (1) assess the relationship between infection in ibexes (detection of serum antibodies and/or of cb dna in tissues) and cb dna presence in ticks hosted by the same ibexes; ... | 2018 | 29478883 |
| linking seasonal home range size with habitat selection and movement in a mountain ungulate. | space use by animals is determined by the interplay between movement and the environment, and is thus mediated by habitat selection, biotic interactions and intrinsic factors of moving individuals. these processes ultimately determine home range size, but their relative contributions and dynamic nature remain less explored. we investigated the role of habitat selection, movement unrelated to habitat selection and intrinsic factors related to sex in driving space use and home range size in iberia ... | 2018 | 29318021 |
| fertilizing capacity of vitrified epididymal sperm from iberian ibex (capra pyrenaica). | in this study, we successfully described for the first time a vitrification of epididymal iberian ibex spermatozoa. spermatozoa from epididymis were obtained from 15 iberian ibex. the right epididymis' semen sample was vitrified and the left one was frozen. after thawing/warming, samples were selected by density gradient. sperm characteristics from each treatment were evaluated. to test the spermatozoa fertilization ability, heterologous ivf was carried out using bovine oocytes. despite of the o ... | 2018 | 29288975 |
| investigation of radiomic signatures for local recurrence using primary tumor texture analysis in oropharyngeal head and neck cancer patients. | radiomics is one such "big data" approach that applies advanced image refining/data characterization algorithms to generate imaging features that can quantitatively classify tumor phenotypes in a non-invasive manner. we hypothesize that certain textural features of oropharyngeal cancer (opc) primary tumors will have statistically significant correlations to patient outcomes such as local control. patients from an irb-approved database dispositioned to (chemo)radiotherapy for locally advanced opc ... | 2018 | 29367653 |
| guidelines and experience using imaging biomarker explorer (ibex) for radiomics. | imaging biomarker explorer (ibex) is an open-source tool for medical imaging radiomics work. the purpose of this paper is to describe how to use ibex's graphical user interface (gui) and to demonstrate how ibex calculated features have been used in clinical studies. ibex allows for the import of dicom images with dicom radiation therapy structure files or pinnacle files. once the images are imported, ibex has tools within the data selection gui to manipulate the viewing of the images, measure vo ... | 2018 | 29364284 |
| toxoplasma gondii in sympatric domestic and wild ungulates in the mediterranean ecosystem. | toxoplasma gondii is a zoonotic protozoan of worldwide distribution. the present study provides information on risk factors affecting t. gondii infection in domestic and free-ranging wild ungulates sharing habitats in mediterranean ecosystems in spain. serum samples from 482 extensively reared domestic ruminants and 2351 wild ungulates were tested for t. gondii antibodies using the modified agglutination test (mat, cut-off 1:25). toxoplasma gondii seroprevalence was 41.2% of 194 sheep, 18.6% of ... | 2018 | 29344801 |
| tear production, intraocular pressure and conjunctival bacterial flora in selected captive wild ruminants. | evaluation of tear production (schirmer's tear test, stt) and measurement of intraocular pressure (iop) were performed in a population of captive wild ungulates in a slovenian zoo during routine annual health check. | 2018 | 28493440 |
| responses of snow leopards, wolves and wild ungulates to livestock grazing in the zorkul strictly protected area, tajikistan. | long recognized as a threat to wildlife, livestock grazing in protected areas has the potential to undermine conservation goals, via competition, habitat degradation, human-carnivore conflict and disruption of predator-prey relationships. in the strictly protected area zorkul in tajikistan (zorkul reserve), grazing is commonplace despite official prohibition, with potentially detrimental effects on local fauna, in particular, snow leopard panthera uncia, wolf canis lupus, brown bear ursus arctos ... | 2018 | 30500847 |
| forecasting the response to global warming in a heat-sensitive species. | avoiding hyperthermia entails considerable metabolic costs for endotherms. such costs increase in warm conditions, when endotherms may trade food intake for cooler areas to avoid heat stress and maximize their energy balance. the need to reduce heat stress may involve the adoption of tactics affecting space use and foraging behaviour, which are important to understand and predict the effects of climate change and inform conservation. we used resource selection models to examine the behavioural r ... | 2019 | 30816191 |
| in situ hybridization for localization of ovine herpesvirus 2, the agent of sheep-associated malignant catarrhal fever, in formalin-fixed tissues. | a constraint on understanding the pathogenesis of malignant catarrhal fever (mcf) is the limited number of tools to localize infected cells. the amount of detectable virus, visualized in the past either by immunohistochemistry or in situ hybridization (ish), has been modest in fixed or frozen tissues. this complicates our understanding of the widespread lymphoid proliferation, epithelial necrosis/apoptosis, and arteritis-phlebitis that characterize mcf. in this work, we developed a probe-based i ... | 2019 | 30222071 |
| individual stress responses to sarcoptes scabiei infestation in iberian ibex, capra pyrenaica. | in this study we have monitored the stress of iberian ibex at individual level within the course of an experimental infection with sarcoptes scabiei mites. for this purpose we have measured faecal 11-ketoetiocholanolone (11-k) using high-performance liquid chromatography coupled with tandem mass spectrometry (hplc-ms/ms). we used linear mixed models to explore the effects of host sex and age, clinic (mange status) and time (number of days post-infection) on the concentration of faecal 11-k. the ... | 2019 | 31095943 |
| pathological and molecular characterisation of peste des petits ruminants in nubian ibex (capra nubiana) in israel. | peste des petits ruminants (ppr) is a devastating disease that generally affects sheep and goats, mostly in asia, the middle east and africa. the disease has been declared a target for global eradication. despite its high prevalence in domestic flocks and its high seroprevalence among wildlife, it is rarely reported as a fulminant disease in wild ruminant species (with the exception of central asia). in this report, we describe a severe ppr outbreak in a zoo herd of nubian ibex (capra nubiana), ... | 2019 | 31089959 |
| software comparison to analyze bone radiomics from high resolution cbct scans of mandibular condyles. | radiomics refers to the extraction and analysis of advanced quantitative imaging from medical images to diagnose and/or predict diseases. in the dentistry field, the bone data from mandibular condyles could be computationally analyzed using the voxel information provided by high-resolution cbct scans to increase the diagnostic power of temporomandibular joint (tmj) conditions. however, such quantitative information demands innovative computational software, algorithm implementation, and validati ... | 2019 | 31075043 |
| parallax of the ibex ribbon indicates a spatially-retained source. | in 2009, the interstellar boundary explorer (ibex) discovered the existence of a narrow "ribbon" of intense energetic neutral atom (ena) emission projecting approximately a circle in the sky. it is believed that the ribbon originates from outside of the heliopause in radial directions ( r ) perpendicular to the local interstellar magnetic field (ismf), b , i.e., b∙ r = 0. swaczyna et al. (2016a) estimated the distance to the ibex ribbon via the parallax method comparing the ribbon position obser ... | 2019 | 31395988 |
| strong scattering of ~kev pickup ions in the local interstellar magnetic field draped around our heliosphere: implications for the ibex ribbon's source and imap. | the leading hypothesis for the origin of the interstellar boundary explorer (ibex) "ribbon" of enhanced energetic neutral atoms (enas) from the outer heliosphere is the secondary ena mechanism, whereby neutralized solar wind ions escape the heliosphere and, after several charge-exchange processes, may propagate back toward earth primarily in directions perpendicular to the local interstellar magnetic field (ismf). however, the physical processes governing the parent protons outside of the heliop ... | 2019 | 31359881 |
| technical note: proof of concept for radiomics-based quality assurance for computed tomography. | routine quality assurance (qa) testing to identify malfunctions in medical imaging devices is a standard practice and plays an important role in meeting quality standards. however, current daily computed tomography (ct) qa techniques have proven to be inadequate for the detection of subtle artifacts on scans. therefore, we investigated the ability of a radiomics phantom to detect subtle artifacts not detected in conventional daily qa. | 2019 | 31609076 |
| inbreeding reduces long-term growth of alpine ibex populations. | many studies document negative inbreeding effects on individuals, and conservation efforts to preserve rare species routinely employ strategies to reduce inbreeding. despite this, there are few clear examples in nature of inbreeding decreasing the growth rates of populations, and the extent of population-level effects of inbreeding in the wild remains controversial. here, we take advantage of a long-term dataset of 26 reintroduced alpine ibex (capra ibex ibex) populations spanning nearly 100 yea ... | 2019 | 31477848 |
| how sensitive and specific is the visual diagnosis of sarcoptic mange in free-ranging iberian ibexes? | sarcoptic mange is a broadly distributed parasitic disease caused by sarcoptes scabiei that affects wild mammals from all over the world, including the iberian ibex (capra pyrenaica). selective culling of the scabietic individuals is the main management measure for disease control in iberian ibex populations. although visual identification of mange-compatible lesions is the reference method to decide the target individual, both false negative and positive cases are common in the wild. the aim of ... | 2019 | 31416471 |
| climate, fascism, and ibex: experiments in using population dynamics modeling as a historiographical tool. | in the interwar years the gran paradiso ibex population followed two subsequent, contrasting trends: a steady rise once the national park was established in 1922, followed by a precipitous fall after the fascist regime took direct control of conservation in 1934, which almost led to the colony's extinction. this paper addresses the issue of how models taken from population ecology may inform historical narratives. the data for the interwar years were analyzed using a statistical model based on c ... | 2019 | 31321590 |
| unusual topographic specializations of retinal ganglion cell density and spatial resolution in a cliff-dwelling artiodactyl, the nubian ibex (capra nubiana). | the nubian ibex (capra nubiana) occurs in information-rich visual habitats including the edges of cliffs and escarpments. in addition to needing enhanced spatial resolution to find food and detect predators, enhanced visual sampling of the lower visual field would be advantageous for the control of locomotion in such precarious terrains. using retinal wholemounts and stereology, we sought to measure how the ganglion cell density varies across the retina of the nubian ibex to reveal which portion ... | 2019 | 31045240 |
| reproducibility and non-redundancy of radiomic features extracted from arterial phase ct scans in hepatocellular carcinoma patients: impact of tumor segmentation variability. | the reproducibility and non-redundancy of radiomic features are challenges in accelerating the clinical translation of radiomics. in this study, we focused on the robustness and non-redundancy of radiomic features extracted from computed tomography (ct) scans in hepatocellular carcinoma (hcc) patients with respect to different tumor segmentation methods. | 2019 | 31032192 |
| brucella melitensis rev.1 vaccination generates a higher shedding risk of the vaccine strain in alpine ibex (capra ibex) compared to the domestic goat (capra hircus). | epidemiological investigations implemented in wild and domestic ruminants evidenced a reservoir for brucella in capra ibex in the french alps. vaccination was considered as a possible way to control brucella infection in this wildlife population. twelve ibexes and twelve goats were allocated into four groups housed separately, each including six males or six non-pregnant females. four to five animals were vaccinated and one or two animals were contact animals. half of the animals were necropsied ... | 2019 | 31775863 |
| method validation, reference values, and characterization of acute-phase protein responses to experimentally induced inflammation and bluetongue virus infection in the iberian ibex. | acute phase protein (app) concentrations can change due to inflammation and be used to monitor disease in the iberian ibex (capra pyrenaica). | 2019 | 31746492 |
| seventy-five mosses and liverworts found frozen with the late neolithic tyrolean iceman: origins, taphonomy and the iceman's last journey. | the iceman site is unique in the bryology of the quaternary. only 21 bryophytes (mosses and liverworts) grow now in the immediate vicinity of the 5,300 year old iceman discovery site at 3,210m above sea level in the ötztal alps, italy. by contrast 75 or more species including at least ten liverworts were recovered as subfossils frozen in, on and around the iceman from before, at and after his time. about two thirds of the species grow in the nival zone (above 3,000m above sea level) now while ab ... | 2019 | 31665165 |
| sanitary emergencies at the wild/domestic caprines interface in europe. | population density and distribution of the four native european wild caprines (rupicapra rupicapra, rupicapra pyrenaica, capra ibex, capra pyrenaica) have increased in recent decades. the improved conservation status of this valuable wildlife, while a welcome event in general terms, is at the same time a matter of concern since, intuitively, frequent and tighter contacts with sympatric livestock imply a greater risk of cross-transmission of emerging and re-emerging pathogens, and offer unexpecte ... | 2019 | 31694211 |
| sequencing and characterization of the complete mitochondrial genome of mishmi takin (budorcas taxicolor taxicolor) and comparison with the other caprinae species. | mishmi takin (budorcas taxicolor taxicolor) is an endangered and least studies species. we sequenced and annotated a 16,584 bp long complete mitogenome of mishmi takin (b. t. taxicolor). it was encoded by 37 genes: 13 protein-coding genes (pcgs), two ribosomal rna genes, 22 transfer rna, and non-coding control region. all trna genes show a typical secondary cloverleaf structure, except trnaser(agy) in which dihydrouridine arm did not form a stable structure. we observed 82 bp nucleotide deletion ... | 2019 | 31254580 |
| screening of wild ruminants from the kaunertal and other alpine regions of tyrol (austria) for vector-borne pathogens. | knowledge about vector-borne pathogens important for human and veterinary medicine in wild ruminants in tyrol (austria) is scarce. blood samples from alpine ibex (capra ibex; n = 44), alpine chamois (rupicapra rupicapra; n = 21), roe deer (capreolus capreolus; n = 18) and red deer (cervus elaphus; n = 6) were collected over a period of 4 years (2015-2018) in four regions in north tyrol, with a primary focus on the kaunertal. blood spots on filter paper were tested for the presence of dna of vect ... | 2019 | 31375956 |
| mycoplasma conjunctivae in insect vectors and anatomic locations related to transmission and persistence. | mycoplasma conjunctivae is an obligate microparasite that causes infectious keratoconjunctivitis (ikc) in caprinae species. ikc is a long-recognised disease, but little attention has been paid to the mechanisms of transmission of the mycoplasma and its occurrence in locations other than the eyes. in this study, the presence of m. conjunctivae is assessed in the eyes, external ear canals (eec), nasal cavity, and vagina of host species as well as in potential vectors, which may be involved in the ... | 2019 | 30593383 |
| purging of highly deleterious mutations through severe bottlenecks in alpine ibex. | human activity has caused dramatic population declines in many wild species. the resulting bottlenecks have a profound impact on the genetic makeup of a species with unknown consequences for health. a key genetic factor for species survival is the evolution of deleterious mutation load, but how bottleneck strength and mutation load interact lacks empirical evidence. we analyze 60 complete genomes of six ibex species and the domestic goat. we show that historic bottlenecks rather than the current ... | 2020 | 32081890 |
| assessing possible hybridization among managed nubian ibex in north america. | hybridization among closely related species is a concern in zoo and aquarium populations where unpedigreed animals are frequently exchanged with the private sector. in this study, we examine possible hybridization in a group of nubian ibex (capra nubiana) imported into the association of zoos and aquariums' (aza) species survival program (ssp) from a private institution. these individuals appeared smaller in stature than adult ssp nubian ibex and were excluded from breeding recommendations over ... | 2020 | 31833594 |
| reliability and prognostic value of radiomic features are highly dependent on choice of feature extraction platform. | to investigate the effects of image biomarker standardisation initiative (ibsi) compliance, harmonisation of calculation settings and platform version on the statistical reliability of radiomic features and their corresponding ability to predict clinical outcome. | 2020 | 32483644 |
| ibex-associated malignant catarrhal fever in duikers (cephalophus spp). | eight duikers, representing 3 different species cohoused in a single zoological collection, died in a 10-month period. black, red-flanked, and yellow-backed duikers were affected, appearing clinically with a combination of anorexia, diarrhea, ataxia, tremors, and/or stupor, followed by death within 72 hours of onset of clinical signs. consistent gross findings were pulmonary ecchymoses (8/8), generalized lymphadenomegaly (6/8), ascites (5/8), and pleural effusion (4/8). dense lymphocyte infiltra ... | 2020 | 32406327 |
| sars-cov-2 diagnostic diary: from rumors to the first case. early reports of molecular tests from the military research and diagnostic institute of rio de janeiro. | corona virus disease (covid-19) presents a serious threat to global health. a historical timeline of early molecular diagnostics from government alert (january 22) (d) was presented. after in silico analysis, brazilian army institute of biology (ibex-rj) tested samples in house using real-time reverse transcriptase polymerase chain reaction (rt-pcr) (fast mode) based on centers for disease control and prevention (cdc) recommendations. first cases from brazil, rio de janeiro, ibex, and diagnosis ... | 2020 | 32667461 |
| long-term monitoring of the iberian ibex population in the sierra nevada of the southeast iberian peninsula. | this dataset provides long-term information on the presence of the iberian ibex (capra pyrenaica hispanica schimper, 1848) in sierra nevada (se iberian peninsula). data on the abundance and demographic structure of the iberian ibex population were compiled over the last three decades. transects were laid out to record different variables such as the number of individuals sighted, the perpendicular distance of each group of iberian ibex to the transect line and sex as well as age of individuals i ... | 2020 | 32587252 |
| re-emergence of bluetongue virus serotype 4 in iberian ibex (capra pyrenaica) and sympatric livestock in spain, 2018-2019. | between early october and mid-december 2018, mortalities were detected in iberian ibex (capra pyrenaica) populations in southern spain. in the same region and period, bluetongue virus (btv) circulation was also reported in sentinel and clinically affected domestic ruminant herds. molecular analyses confirmed btv serotype 4 (btv-4) infection in eight iberian ibexes from six hunting areas, and in 46 domestic ruminants from seven herds in close proximity to affected hunting estates. histopathologic ... | 2020 | 32573968 |
| radiomics prediction of egfr status in lung cancer-our experience in using multiple feature extractors and the cancer imaging archive data. | we investigated the performance of multiple radiomics feature extractors/software on predicting epidermal growth factor receptor mutation status in 228 patients with non-small cell lung cancer from publicly available data sets in the cancer imaging archive. the imaging and clinical data were split into training (n = 105) and validation cohorts (n = 123). two of the most cited open-source feature extractors, ibex (1563 features) and pyradiomics (1319 features), and our in-house software, columbia ... | 2020 | 32548300 |
| radiomics method for the differential diagnosis of radionecrosis versus progression after fractionated stereotactic body radiotherapy for brain oligometastasis. | stereotactic radiotherapy (srt) is recommended for treatment of brain oligometastasis (bom) in patients with controlled primary disease. where contrast enhancement enlargement occurs during follow-up, distinguishing between radionecrosis and progression presents a critical challenge. without pathological confirmation, decision-making may be inappropriate and delayed. quantitative imaging features extracted from routinely performed examinations are of interest in potentially addressing this probl ... | 2020 | 32160109 |
| genetic epidemiology of the alpine ibex reservoir of persistent and virulent brucellosis outbreak. | while it is now broadly accepted that inter-individual variation in the outcomes of host-pathogen interactions is at least partially genetically controlled, host immunogenetic characteristics are rarely investigated in wildlife epidemiological studies. furthermore, most immunogenetic studies in the wild focused solely on the major histocompatibility complex (mhc) diversity despite it accounts for only a fraction of the genetic variation in pathogen resistance. here, we investigated immunogenetic ... | 2020 | 32157133 |
| suttearima: short-term forecasting method, a case: covid-19 and stock market in spain. | this study aimed to predict the short-term of confirmed cases of covid-19 and ibex in spain by using suttearima method. confirmed data of covid-19 in spanish was obtained from worldometer and spain stock market data (ibex 35) was data obtained from yahoo finance. data started from 12 february 2020-09 april 2020 (the date on covid-19 was detected in spain). the data from 12 february 2020-02 april 2020 using to fitting with data from 03 april 2020 - 09 april 2020. based on the fitting data, we can ... | 2020 | 32361446 |
| complete genome sequence of mycoplasma feriruminatoris strain ivb14/od_0535, isolated from an alpine ibex in a swiss zoo. | mycoplasma feriruminatoris is a fast-growing and genetically tractable mycoplasma species. we sequenced the swiss strain ivb14/od_0535, isolated from an alpine ibex. this strain has a circular genome of 1,027,435 bp with a g+c content of 24.3%. it encodes 835 open reading frames (orfs), 2 rrna operons, and 30 trnas. | 2020 | 32193243 |
| spatiotemporal monitoring of selected pathogens in iberian ibex (capra pyrenaica). | an epidemiological surveillance programme was carried out to assess exposure and spatiotemporal patterns of selected pathogens (brucella spp., mycobacterium avium subsp. paratuberculosis (map), mycoplasma agalactiae, pestivirus and bluetongue virus (btv)) in iberian ibex (capra pyrenaica) from andalusia (southern spain), the region with the largest population of this species. a total of 602 animals in five distribution areas were sampled during 2010-2012 (p1) and 2013-2015 (p2). the rose bengal ... | 2020 | 32303109 |
| identifying bap1 mutations in clear-cell renal cell carcinoma by ct radiomics: preliminary findings. | to evaluate the potential application of computed tomography (ct) radiomics in the prediction of brca1-associated protein 1 (bap1) mutation status in patients with clear-cell renal cell carcinoma (ccrcc). in this retrospective study, clinical and ct imaging data of 54 patients were retrieved from the cancer genome atlas-kidney renal clear cell carcinoma database. among these, 45 patients had wild-type bap1 and nine patients had bap1 mutation. the texture features of tumor images were extracted u ... | 2020 | 32185138 |
| unilateral single vaginal ectopic ureter with ipsilateral hypoplastic and degenerated kidney associated with infertility in iberian ibex (capra pyrenaica) does. | this article describes the urinogenital condition of three female iberian ibexes (capra pyrenaica-one infertile 3-yr-old adult and two prepubertal animals aged 1 (pp1) and 2 (pp2) yr, respectively, all raised in captivity. all showed constant urinal dribbling, leading to ulcerative dermatitis in the vulvar area. housed in a stable with other females, the adult did not become pregnant after male contact in either of two consecutive mating seasons. vaginoscopy and laparoscopic exploration performe ... | 2020 | 32212563 |
| a general framework for modeling population abundance data. | time-series data resulting from surveying wild animals are often described using state-space population dynamics models, in particular with gompertz, beverton-holt, or moran-ricker latent processes. we show how hidden markov model methodology provides a flexible framework for fitting a wide range of models to such data. this general approach makes it possible to model abundance on the natural or log scale, include multiple observations at each sampling occasion and compare alternative models usi ... | 2020 | 31342508 |
| issues and opportunities associated with trophy hunting and tourism in khunjerab national park, northern pakistan. | trophy hunting and mass tourism are the two major interventions designed to provide various socioeconomic and ecological benefits at the local and regional levels. however, these interventions have raised some serious concerns that need to be addressed. this study was conducted in khunjerab national park (knp) with an aim to analyze comparatively the socioeconomic and ecological impacts of trophy hunting and mass tourism over the last three decades within the context of sustainability. focus gro ... | 2020 | 32244688 |
| eimeria tamimi sp. n. (apicomplexa: eimeriidae) from the rock hyrax (procavia capensis jayakari) in central saudi arabia. | faecal samples from the rock hyrax (procavia capensis jayakari thomas) were collected from the ibex reserve in central saudi arabia. eimerian oocysts, which are believed to represent a new species described here as eimeria tamimi sp. n., were detected in 40 out of 93 samples. oocysts were fully sporulated in 24-48 hours at 25 ± 2 °c. sporulated oocysts of e. tamimi sp. n. were ovoid, measuring 35-42 × 19-25 μm (39 × 23 μm), a length/width ratio 1.5-2 (1.7). oocyst wall was bilayered and measured ... | 2020 | 32075950 |
| foot health and prevalence of dichelobacter nodosus in 11 ungulate species at berne animal park. | dichelobacter nodosus (d. nodosus) is the etiological agent of ovine footrot affecting mainly sheep worldwide, but also free-ranging wild ungulates such as alpine ibex (capra ibex ibex) and mufflon (ovis orientalis orientalis). a nationwide ovine footrot eradication program is planned for the years to come, based on polymerase chain reaction (pcr)-testing of interdigital swab samples and regular footbathing. in this cross-sectional study, we clinically evaluated the foot health and analysed pres ... | 2020 | 33140726 |
| adaptability, resilience and environmental buffering in european refugia during the late pleistocene: insights from la riera cave (asturias, cantabria, spain). | the upper palaeolithic in europe was a time of extensive climatic changes that impacted on the survival and distribution of human populations. during the late glacial maximum (lgm), southern european peninsulas were refugia for flora, fauna, and human groups. one of these refugia, the cantabrian region (northern atlantic spain), was intensively occupied throughout the upper palaeolithic. characterising how climatic events were expressed in local environments is crucial to understand human and an ... | 2020 | 31988327 |
| genetic characterisation of wild ungulates: successful isolation and analysis of dna from widely available bones can be cheap, fast and easy. | genetic characterisation of wild ungulates can be a useful tool in wildlife management and in obtaining a greater understanding of their biological and ecological roles in a wider spatiotemporal context. different ways of optimising methodologies and reducing the costs of genetic analyses using widely available bone tissues collected within regular hunting allocations were examined. successful isolation and analysis of dna from widely available bones can be cheap, fast and easy. in particular, t ... | 2020 | 32973384 |
| detection of porcine circovirus 3 in wildlife species in spain. | porcine circovirus 3 (pcv-3) is the third member of the family circoviridae, genus circovirus, able to infect swine. a high prevalence of viral dna has been recorded in wild boars. recently, pcv-3 dna was identified in italian wild ruminants. based on these previous results, this study assessed the frequency of pcv-3 dna detection in free-ranging ruminants and lagomorpha species in spain. in addition, the genetic characterization of the pcv-3 pcr-positive samples was performed. a total of 801 se ... | 2020 | 32369945 |
| first records of dermacentor albipictus larvae collected by flagging in yukon, canada. | the winter tick (dermacentor albipictus) has garnered significant attention throughout north america for its impact on wildlife health, and especially for moose (alces alces), where high tick burdens may result in host hair loss, anemia, and can prove fatal. the environmental transmission of d. albipictus larvae to a host is a critical event that has direct impact on infestation success, yet in-field observations of this life stage are lacking. in yukon, canada, d. albipictus had previously been ... | 2020 | 33176864 |
| stable body size of alpine ungulates. | in many species, decreasing body size has been associated with increasing temperatures. although climate-induced phenotypic shifts, and evolutionary impacts, can affect the structure and functioning of marine and terrestrial ecosystems through biological and metabolic rules, evidence for shrinking body size is often challenged by (i) relatively short intervals of observation, (ii) a limited number of individuals, and (iii) confinement to small and isolated populations. to overcome these issues a ... | 2020 | 32874622 |
| identifying maintenance hosts for infection with dichelobacter nodosus in free-ranging wild ruminants in switzerland: a prevalence study. | footrot is a worldwide economically important, painful, contagious bacterial foot disease of domestic and wild ungulates caused by dichelobacter nodosus. benign and virulent strains have been identified in sheep presenting with mild and severe lesions, respectively. however, in alpine ibex (capra ibex ibex), both strains have been associated with severe lesions. because the disease is widespread throughout sheep flocks in switzerland, a nationwide footrot control program for sheep focusing on vi ... | 2020 | 31917824 |
| the corporate purpose of spanish listed companies: neurocommunication research applied to organizational intangibles. | purpose driven companies have developed their corporate culture with a commitment to stakeholders, sustainable development goals, and social responsibility, prioritizing the management of organizational intangibles over capital. the overall objective of this research is to gain knowledge regarding the attention and emotional intensity registered by young spanish university students when visualizing corporate purpose versus corporate visual identity, as well as the image of the chairman of the ma ... | 2020 | 33117206 |
| radiomics approaches for predicting liver fibrosis with nonenhanced t1 -weighted imaging: comparison of different radiomics models. | liver fibrosis is a common process resulting from various etiologies. sustained progression of liver fibrosis leads to cirrhosis, even hepatocellular carcinoma. thus, noninvasive staging of liver fibrosis is of clinical importance. radiomics is an emerging approach for staging liver fibrosis. however, the feature selection methods and classifier models are complicated, and may result in a discrepancy of diagnostic performance owing to different radiomics models. | 2020 | 33043991 |
| investigating the psychology of financial markets during covid-19 era: a case study of the us and european markets. | the novel coronavirus (covid-19) has imperatively shaken the behavior of the global financial markets. this study estimated the impact of covid-19 on the behavior of the financial markets of europe and the us. the results revealed that the returns of the s&p 500 index have been greatly affected by a lockdown in the us owing to covid-19. however, the health crisis generated due to the novel coronavirus significantly decreased the stock returns of the nasdaq composite index. the results also showe ... | 2020 | 33013504 |
| radiomics features of ascending and descending nasopharyngeal carcinoma. | to evaluate the application value of ct-based radiomics features for the ascending and descending types of nasopharyngeal carcinoma (npc). | 2020 | 32879076 |
| association of bone mineral density with bone texture attributes extracted using routine magnetic resonance imaging. | dual-energy x-ray absorptiometry (dxa)-derived bone mineral density (bmd) often fails to predict fragility fractures. quantitative textural analysis using magnetic resonance imaging (mri) may potentially yield useful radiomic features to predict fractures. we aimed to investigate the correlation between bmd and texture attributes (tas) extracted from mri scans and the interobserver reproducibility of the analysis. | 2020 | 32876107 |
| mri-based radiomics signature for localized prostate cancer: a new clinical tool for cancer aggressiveness prediction? sub-study of prospective phase ii trial on ultra-hypofractionated radiotherapy (airc ig-13218). | radiomic involves testing the associations of a large number of quantitative imaging features with clinical characteristics. our aim was to extract a radiomic signature from axial t2-weighted (t2-w) magnetic resonance imaging (mri) of the whole prostate able to predict oncological and radiological scores in prostate cancer (pca). | 2020 | 32852590 |
| association of quantitative mri-based radiomic features with prognostic factors and recurrence rate in oropharyngeal squamous cell carcinoma. | radiomics focuses on extracting a large number of quantitative imaging features and testing both their correlation with clinical characteristics and their prognostic and predictive values. we propose a radiomic approach using magnetic resonance imaging (mri) to decode tumor phenotype and local recurrence in oropharyngeal squamous cell carcinoma (opscc). the contrast-enhanced t1-weighted sequences from baseline mri examinations of opscc patients treated between 2008 and 2016 were retrospectively ... | 2020 | 32787435 |
| vigilance behaviour in siberian ibex (capra sibirica): effect of group size, group type, sex and age. | gregarious prey species modify their behaviours in response to predation risk in two ways: by increasing vigilance level or enlarging herd size. however, individuals of various sex and age have different responses to the same danger, and even the same individuals react differently depending on their status during biological events or within group types. but how these factors influence the interactions between vigilance level and group size is still poorly understood. therefore, we studied this p ... | 2020 | 31857139 |
| ibex: modular open-source software for digital radiography. | a device-independent software package, named ibex, is developed to accelerate the research and development efforts for x-ray imaging setups such as chest radiography, linear and multidirectional tomography, and dental and skeletal radiography. its extension mechanism makes the software adaptable for a wide range of digital x-ray imaging hardware combinations and provides capabilities for researchers to develop image processing plug-ins. independent of the x-ray sensor technology, ibex could inte ... | 2020 | 31845123 |
| effects of variability in radiomics software packages on classifying patients with radiation pneumonitis. | purpose: while radiomics feature values can differ when extracted using different radiomics software, the effects of these variations when applied to a particular clinical task are currently unknown. the goal of our study was to use various radiomics software packages to classify patients with radiation pneumonitis (rp) and to quantify the variation in classification ability among packages. approach: a database of serial thoracic computed tomography scans was obtained from 105 patients with esop ... | 2020 | 32118090 |
| the global epidemiology of brucella infections in terrestrial wildlife: a meta-analysis. | brucellosis is a widespread zoonotic disease with serious consequences on human and animal health. brucella infections were reported in many terrestrial wild animals, from subtropical and temperate regions to arctic regions. in many areas, the epidemiology of brucellosis in wildlife is closely associated with the occurrence of the disease in livestock. some wild species may contribute to the re-introduction of brucella infections in livestock (spillback), even in officially brucellosis-free (obf ... | 2020 | 32679611 |
| remote mapping of foodscapes using suas and a low cost bg-nir sensor. | the assessment of landscape condition for large herbivores, also known as foodscapes, is fast gaining interest in conservation and landscape management programs worldwide. although traditional approaches are now being replaced by satellite imagery, several technical issues still need to be addressed before full standardization of remote sensing methods for these purposes. we present a low-cost method, based on the use of a modified blue/green/near-infrared (bg-nir) camera housed on a small-unman ... | 2020 | 32105932 |
| cone-beam ct radiomics features might improve the prediction of lung toxicity after sbrt in stage i nsclc patients. | stereotactic body radiotherapy (sbrt) is the standard care for inoperable early stage non-small cell lung cancer (nsclc). the purpose of our study was to investigate whether a prediction model based on cone-beam ct (cbct) plus pretreatment ct radiomics features could improve the prediction of tumor control and lung toxicity after sbrt in comparison to a model based on pretreatment ct radiomics features alone. | 2020 | 32061061 |
| turbulence in the local interstellar medium and the ibex ribbon. | the effects of turbulence in the very local interstellar medium (vlism) have been proposed by giacalone & jokipii (2015) to be important in determining the structure of the interstellar boundary explorer (ibex) ribbon via particle trapping by magnetic mirroring. we further explore this effect by simulating the motion of charged particles in a turbulent magnetic field superposed on a large-scale mean field, which we consider to be either spatially-uniform or a draped field derived from a 3d mhd s ... | 2020 | 32020922 |
| ultra-rapid cooling of ibex sperm by spheres method does not induce a vitreous extracellular state and increases the membrane damages. | sperm cryopreservation by ultra-rapid cooling based on dropping small volumes of sperm suspension directly into liquid nitrogen, has been successful in some wild ruminant species, including the iberian ibex (capra pyrenaica). in ultra-rapid cooling, the contents of these droplets are expected to enter a stable, glass-like state, but to the best of our knowledge no information exists regarding the presence or absence of ice formation in the extracellular milieu when using this technique. differen ... | 2020 | 31978160 |
| dichelobacter nodosus in sheep, cattle, goats and south american camelids in switzerland-assessing prevalence in potential hosts in order to design targeted disease control measures. | footrot is a contagious foot disease caused by the bacterium dichelobacter nodosus (d. nodosus) that affects sheep worldwide. due to substantial economic and welfare impact, various countries have developed control programs against footrot. the aim of this cross-sectional study was to estimate the national prevalence of virulent and benign d. nodosus in switzerland in the four domestic ruminant species sheep, cattle, goats and south american camelids (sac) to detect potential host populations an ... | 2020 | 31109750 |
| prediction of response to neoadjuvant chemoradiotherapy by mri-based machine learning texture analysis in rectal cancer patients. | neoadjuvant chemoradiotherapy (ncrt) followed by surgical resection is the standard treatment for locally advanced rectal cancer (larc). radiomics can be used as noninvasive biomarker for prediction of response to therapy. the main aim of this study was to evaluate the association of mri texture features of larc with ncrt response and the effect of laplacian of gaussian (log) filter and feature selection algorithm in prediction process improvement. | 2020 | 31456114 |
| first global images of ion energization in the terrestrial foreshock by the interstellar boundary explorer. | the interstellar boundary explorer (ibex) mission provides global energetic neutral atom (ena) observations from the heliosphere and the earth's magnetosphere, including spatial, temporal, and energy information. ibex views the magnetosphere from the sides and almost always perpendicular to noon-midnight plane. we report the first ena images of the energization process in the earth's ion foreshock and magnetosheath regions. we show ena flux and spectral images of the dayside magnetosphere with s ... | 2020 | 33132458 |
| technical note: an ibex adaption toward image biomarker standardization. | interest in the field of radiomics is rapidly growing because of its potential to characterize tumor phenotype and provide predictive and prognostic information. nevertheless, the reproducibility and robustness of radiomics studies are hampered by the lack of standardization in feature definition and calculation. in the context of the image biomarker standardization initiative (ibsi), we investigated the grade of compliance of the image biomarker explorer (ibex), a free open-source radiomic soft ... | 2020 | 31830303 |
| measurement of the force required by blunt-tipped microcannulas to perforate the facial artery. | to measure the force required by blunt-tipped microcannulas of various sizes to penetrate the wall of the facial artery. | 2020 | 30624414 |
| epitheliotropic infections in wildlife ruminants from the central alps and stelvio national park. | the mountain chain of the alps, represents the habitat of alpine fauna where the red deer (cervus elaphus) population is the outmost numerous, followed by the chamois (rupicapra rupicapra) and the alpine ibex (capra ibex) at higher altitudes. previous reports showed the circulation of epitheliotropic viruses, belonging to the families papillomaviridae and poxviridae, causing skin and mucosal lesions in wild ruminants of the stelvio national park, situated in the area. to deepen our knowledge on ... | 2020 | 32426384 |
| spatio-temporal patterns of sarcoptic mange in red deer and iberian ibex in a multi-host natural park. | the reliance on multiple hosts to survive is what makes the management and control of multi-host infectious agents challenging. sarcoptes scabiei causes sarcoptic mange in a wide range of mammal species with ungulates being an important host. little is known about the role different ungulates play in sustaining endemic transmission of the disease and no study has yet to describe the long-term multi-host sarcoptic infestation dynamics in free-ranging wildlife. here, we explore 24 years of sarcopt ... | 2020 | 31837510 |