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control of sarcoptes scabiei var. suis with ivermectin: influence on scratching behaviour of fattening pigs and occurrence of dermatitis at slaughter.the behaviour of fattening pigs, the occurrence of erythematous papular dermatitis in pigs at slaughter and the effects of treatment for mange with ivermectin at the start of the fattening period were evaluated at ten farms. at each farm, trial pigs were randomly allotted to a control or a treated group. at the start of the trial, the control group was injected intramuscularly with 5 mg kg-1 levamisole, and the treated group was injected subcutaneously with 300 micrograms kg-1 ivermectin. skin s ...19957676592
efficacy of injectable moxidectin against mixed (psoroptes ovis and sarcoptes scabiei var. ovis) mange infestation in sheep.field efficacy of injectable moxidectin was evaluated in sheep naturally infested with both psoroptes ovis and sarcoptes scabiei var. ovis mange. three groups of 15 ewes were selected from the flock based on parasitological and clinical status. group 1 remained as untreated controls; group 2 animals received a subcutaneous injection of moxidectin at 0.2 mg kg-1 body weight on day 1; group 3 animals received 0.2 mg kg-1 moxidectin twice on day 1 and day 7. efficacy was assessed by taking skin scr ...19957754610
the treatment of scabies with ivermectin.ivermectin is an anthelmintic agent that has been a safe, effective treatment for onchocerciasis (river blindness) when given in a single oral dose of 150 to 200 micrograms per kilogram of body weight. anecdotal reports of improvement in patients who suffered from infestation with the mite sarcoptes scabiei suggest that the ectoparasitic disease scabies might be treated with ivermectin.19957776990
a method for in vitro determination of the acaricidal effect of ivermectin using sarcoptes scabiei var. suis as test organism.an in vitro assay for the acaricidal effect of ivermectin is described. the test is based on the migration ability and survival of sarcoptes scabiei var. suis mites on the surface of agar gels containing the acaricide. the effect of a given concentration of ivermectin is expressed as an activity index (ai) for the mites, calculated from observed migration and mite survival after 24 h of incubation. in order to allow a concentration-effect curve to be based on true values of the acaricide, a meth ...19958533283
ivermectin and crusted (norwegian) scabies. 19958538537
neonatal scabies.between 1981 and 1991, eleven infants (ranging in age from 2 to 9 months) were hospitalized in our department for evaluation of microscopically verified scabies infestations. six presented signs of norwegian scabies. all of the latter infants had been treated (prior to the scabies infestation) for long periods with topical steroids, in most cases for lesions suggestive of atopic dermatitis. we believe that the occurrence of the norwegian form in these newborns was due to localized steroid-induce ...19958575219
serum levels of tumour necrosis factor alpha (tnf-alpha) versus immunoglobulins (igg., igm., and ige.) in egyptian scabietic children.the tumour necrosis factor-alpha (tnf-alpha or cachectin) is a protein produced mainly by macrophages, with a wide range of biological activities and in inflammatory process. on the other hand, scabies is a skin disease caused by sarcoptes scabiei which is typified by severe itching (particularly at night), red papules and often secondary infection. the female mite tunnels in the skin to lay her eggs and the newly hatched mites pass easily from person to person by contact. commonly the infested ...19958586872
infantile acropustulosis in six immigrant children.infantile acropustulosis is a recurrent, pruriginous, vesiculopustular eruption of the palms and soles first described in 1979. we report six cases of infantile acropustulosis in recently emigrated children treated for scabies. clinical follow-up was obtained by questionnaire addressed to patients' families and general practitioners. our study suggests infantile acropustulosis is frequent in immigrant infants and could be a non-specific hypersensitivity reaction to sarcoptes scabiei.19957501548
some effects of sarcoptic mange on dogs.sequential changes in pathology were examined for scabies-infested dogs to determine the effects of infestation with sarcoptes scabiei var. canis. during 8 wk of infestation with s. scabiei, the progression of the disease was evaluated weekly by skin scrape, clinical examination, and blood analyses. at 8 wk, selected organs were microscopically examined for histopathology. all infested dogs developed an advanced level of scabies infestation by 8 wk. of the 36 blood parameters evaluated, only val ...19957472858
the role of mast cells in treatment of scabies.the purpose of this study was to recognize the role of mast cells in the pathogenesis of scabies.19957538495
transmission of sarcoptes scabiei from animal to man and its control.outbreak of sarcoptes scabiei in animals spilling over to man in close association was observed in two adjacent villages, fewgram and nurpur in the district of birbhum, west bengal, from mid-november to mid-december, 1991. nineteen goats and one calf who did not receive any treatment died of sarcoptic manage. all infected animals got cured with external application of deltamethrin, a synthetic pyrethroid and triazapentadiene. human cases were treated successfully with benzene hexachloride (2%).19958699041
infantile acropustulosis--how often is it a sequela of scabies? 19957501565
response of sarcoptes scabiei var. canis (acari: sarcoptidae) to lipids of mammalian skin.bioassays were conducted to determine if sarcoptes scabiei (l.) were attracted to lipid compounds that occur in or on the epidermis of human or other mammalian skin. seventeen lipid compounds attracted s. scabiei including odd and even carbon chain lengths and saturated and unsaturated fatty acids, fatty acid methyl esters, a steroid, a steroid precursor, and a triglyceride. the attractive saturated fatty acids were pentanoic (5:0), hexanoic (6:0), octanoic (8:0), lauric (12:0), pentadecanoic (1 ...19957869340
resistance and immune response in scabies-infested hosts immunized with dermatophagoides mites.seventy-one percent of rabbits immunized with a mixed (50:50) dermatophagoides farinae and d. pteronyssinus house dust mite extract were resistant to infestation by sarcoptes scabiei var. canis. the resistance was evidenced by a marked reduction in parasite load. all immunized hosts developed similar immunogen-specific antibody titers that were independent of the levels of scabies infestation that developed when the hosts were infested with scabies. resistant hosts exhibited significantly lower ...19957611562
clinical picture and antibody response to experimental sarcoptes scabiei var. vulpes infection in red foxes (vulpes vulpes).three red foxes (vulpes vulpes) were experimentally infected with sarcoptes scabiei isolated from a naturally infected wild red fox. a fourth red fox served as a control. the first signs of sarcoptic mange became evident on the 31st day post infection (dpi). the signs gradually increased thereafter and between dpi 49 and 77 characteristic lesions of hyperkeratosis developed. two of the infected foxes developed severe sarcoptic mange, and one of these animals died on dpi 121. the third fox develo ...19958669378
topical application of ivermectin for human ectoparasites.ivermectin is used in veterinary practice against many ectoparasites and endoparasites and is the drug of choice for treatment of human onchocerciasis. this study was carried out to investigate the effect of topical application of this drug against human ectoparasites (sarcoptes scabiei and pediculus humanus capitis). ivernectin was found to have a curative effect on head lice after a single topical application. in patients with scabies, the drug was also found to be effective after a single app ...19958561270
production of il-1 alpha and il-1 beta by human skin equivalents parasitized by sarcoptes scabiei.human skin equivalents (hses) were used as a model to investigate interleukin (il)-1 alpha and il-1 beta secretions by keratinocytes stimulated by sarcoptes scabiei (ss). ss mites burrowed into the stratum corneum when placed on the surface of cultured hses. mites lived for 14 days. mites and mite products induced cells in the hses to secrete il-1 alpha and il-1 beta within 16 hr. scabies mites induced production of greater amounts of il-1 alpha than il-1 beta. hepatocyte growth factor in the cu ...19968885878
responses of sarcoptes scabiei (acari: sarcoptidae) to nitrogenous waste and phenolic compounds.this study found that > or = 1 life stage(s) of sarcoptes scabiei (l.) was significantly attracted to the nitrogenous compounds, guanine, purine, adenine, allantoin, hypoxanthine, xanthine, uric acid, ammonium chloride, ammonium nitrate, and ammonium sulfate. females and larvae responded to all compounds. males responded to all compounds except purine and allantoin. nymphs responded to all compounds except allantoin. some specific concentrations of compounds attracted only 1 life stage but other ...19968742528
immunologic cross-reactivity among various strains of sarcoptes scabiei.varieties of sarcoptes scabiei from different hosts are highly host specific but they are morphologically indistinguishable. the purpose of this study was to investigate the immunologic cross-reactivity among several varieties of scabies mites using serum from a human scabies patient and from several other species of infested hosts. homologous and heterologous crossed-immunoelectrophoretic (cie) analysis of extracts prepared from var. canis (dog) and var. suis (pig) mites yielded very similar an ...19968627503
sarcoptic mange in wild ruminants in zoological gardens in israel.sarcoptic mange (sarcoptes scabiei) occurred among wild ruminant species in five zoological gardens in israel, from 1984 to 1994. infestation of five ruminants by s. scabiei is reported for the first time: mountain gazelles (gazella gazella), nubian ibexes (capra ibex nubiana), a barbary sheep (ammotragus lervia), elands (taurotragus oryx), and an arabian oryx (oryx leucoryx). all animals in the herds were administered ivermectin orally at a dose of 200 micrograms/kg body weight daily for 3 cons ...19968627937
the development of protective immunity in canine scabies.seven of eight dogs that had been previously infested with sarcoptes scabiei var. canis and then cured, expressed protective immunity when experimentally reinfested with scabies. all seven dogs that expressed resistance were spontaneously cleared of scabies by 64 days after they were experimentally reinfested. five of the eight dogs were free of scabies by 24 days. the sequential changes in the inflammatory/immune cellular infiltrate in the scabietic lesions of each dog were determined during th ...19968638386
evaluation of the monitoring of papular dermatitis lesions in slaughtered swine to assess sarcoptic mite infestation.we investigated the association between the presence of papular dermatitis and sarcoptic mite infestation in pigs slaughtered in southern minnesota. following dehairing, a sample of 30 pigs from each of 50 herds was inspected for papular dermatitis lesions. herds were selected after being categorized into one of five categories according to the prevalence and severity of dermatitis lesions. herd infestation with sarcoptic mange was determined by recovery of mites from ear scrapings of slaughtere ...19968638387
a histomorphological study of sarcoptic acariasis in the dog: 19 cases.nineteen cases of canine sarcoptic acariasis (sarcoptes scabiei var. canis) were diagnosed histologically by identifying sarcoptic mites present in the stratum corneum. the inflammatory responses to these mites could be staged as early, fully developed, or late lesions. no histomorphological features were identified that could serve as reliable markers of infestation in the absence of a sectioned mite.19968680917
coexistence of an unusual form of scabies and lepromatous leprosy. a case report.a case of unusual crusted (norwegian) scabies involving the entire skin of a 26 year old brazilian patient with lepromatous leprosy is reported. the more prominent histopathological findings were acanthosis, hyperkeratosis and crusting with many mites of sarcoptes scabiei. in the dermis, numerous foamy histiocytes filled with abundant acid-fast bacilli were seen.19968685047
treatment of sarcoptic mite infestation and mite hypersensitivity in pigs with injectable doramectin.thirty-two pigs were infested experimentally with sarcoptes scabiei var suis and allocated randomly to a medicated group (injected intramuscularly with 300 micrograms doramectin/kg) or an unmedicated group (injected intramuscularly with 1 ml saline/33 kg). they were observed daily for 15 minutes for signs of pruritus, and the ear lesions were assessed and skin scrapings examined for mites on days 7, 14, 21 and 28 after treatment. in the 16 pigs treated with doramectin the ear lesions resolved co ...19968735539
prevalence of sarcoptic mange in fattening pigs sacrificed in a slaughterhouse of northeastern spain.a study was conducted in fattening pigs from ne spain to determine the prevalence of sarcoptic mange. pigs were sacrificed in a slaughterhouse in the province of barcelona (catalonia, ne spain) in november 1990, april 1991, and october 1991. from 7906 pigs slaughtered on those dates, 818 ear scrapings were taken. the survey results indicate that 276 (33.7%) of 818 pigs sampled from 58 (86.6%) of 67 herds were positive for sarcoptes scabiei (de geer). the presence of sarcoptes-induced skin lesion ...19968750691
scabies and leukocytoclastic vasculitis in an hiv-seropositive man. 19968854172
crusted scabies associated with systemic lupus erythematosus: response to benzyl benzoate therapy.a 30-year-old thai woman with systemic lupus erythematosus developed crusting, erythematous scaling plaques on the scalp and neck. histologic section showed numerous mites in the stratum corneum. the diagnosis was further confirmed by identification of sarcoptes scabiei in scraping and potassium hydroxide preparations made from the cutaneous lesions. after applications of 25 per cent benzyl benzoate for one month, there was complete resolution of the parasitic infestation.19968867406
immunohistopathological status of the skin in cases infested with three species of mites.this study was performed on eighty patients with clinical manifestations of scabies. sarcoptes scabiei adult or larva was isolated from 39 patients (48.8%). dermanyssus gallinae (red poultry mite) and dermatophagoides sp. were isolated from 6 and 5 patients respectively. punch biopsies were taken from the patients, stained with haematoxylin and eosin and direct immunofluorescence stain to study the immunopathological status of the skin infested with three species of mites. the results declared t ...19968918029
occupationally acquired infections in health care workers. part ii.health care workers are at occupational risk for a vast array of infections that cause substantial illness and occasional deaths. despite this, few studies have examined the incidence, prevalence, or exposure-associated rates of infection or have considered infection-specific interventions recommended to maintain worker safety.19968967673
activity of doramectin against nematode and arthropod parasites of swine.the efficacy of doramectin, a novel avermectin, was assessed against both naturally-acquired and experimentally-induced infections of gastrointestinal roundworms, lungworms, kidneyworms, lice and mites in studies conducted across north america and europe. twenty-two studies evaluated efficacy against fourth larval and adult stages of the following nematode species: hyostrongylus rubidus, ascaris suum, strongyloides ransomi, oesophagostomum dentatum, oesophagostomum quadrispinulatum, trichuris su ...19968988559
seroprevalence of sarcoptes scabiei var canis antibodies among aborigines in peninsular malaysia.the aborigines or orang asli in peninsular malaysia who are still seminomadic are known to have a close association with dogs. in this study, enzyme-linked immunosorbent assay (elisa) was used to detect anti-sarcoptes scabiei var canis antibodies in this community as a measure of exposure to the mite. out of 312 orang asli tested, 24.7% were positive for polyvalent anti-sarcoptes antibodies. no significant difference was found between the positive rates in males (26.1%) and females (23.6%). only ...19969031401
[animal mite-induced epizoonoses and their significance in dermatology].different mite species may infest humans temporarily; such arthropods should be considered a possible cause of pruritic skin reactions of unclear origin. pseudo-scabies is a common problem. this self-limiting dermatosis may often be misdiagnosed. several mite species including sarcoptes scabiei var. canis, sarcoptes scabiei var. bovis, notoedres cati, cheyletiella yasguri, cheyletiella blakei, dermanyssus gallinae and ophionyssus natricis may infest human skin, causing symptoms. other less commo ...19969036121
the behaviour of sarcoptes scabiei var. hominis in human skin: an ultrastructural study.the biology of sarcoptes scabiei var. hominis is poorly understood because of the lack of an in vivo or in vitro propagation system. to obtain more information on the mite behaviour in its natural habitat we conducted an ultrastructural study of burrows in a number of patients with common scabies. scanning electron microscopy furnished attractive images of the tunnel, parasite body and eggs architecture and demonstrated the presence of holes in the tunnel roof probably representing aeration stru ...19979066149
efficacy of doramectin against intestinal nematodes and sarcoptic manage mites in naturally infected swine.endectocidal efficacy of doramectin administered intramuscularly at a dosage of 300 micrograms/kg was evaluated in 464 pigs naturally infected with intestinal nematodes or mange mites on 14 commercial farms in japan. by doramectin treatment, fecal egg counts were reduced > 99% for ascaris suum, strongyloides ransomi, oesophagostomum dentatum, and trichuris suis; worm counts of t. suis and mite counts of sarcoptes scabiei reduced 90.1% on day 21 and 99.5% on day 28 following treatment, respective ...19979070986
an assessment of the efficacy of deltamethrin with hch for the treatment of sarcoptic mange in camels. 19979090015
[oral treatment of scabies with ivermectin]. 19979132382
evaluation of an enzyme-linked immunosorbent assay (elisa) for the serological diagnosis of sarcoptic mange in swine.an enzyme-linked immunosorbent assay (elisa) using an extract from sarcoptes scabiei var. culpes as antigen was evaluated for its usefulness in monitoring antibodies to s. scabiei var. suis in naturally infected pigs. five hundred and fifty-eight serum samples from certified sarcoptes-free pigs (120 from weaned piglets, 218 from fatteners and 220 from adult sows) and 94 samples from certified sarcoptes-infected pigs (35 from weaned piglets, 45 from fatteners and 14 from adult sows) were examined ...19979187036
topical (pour-on) ivermectin in the treatment of canine scabies.the efficacy of a pour-on formulation of ivermectin at 500 micrograms/kg body weight applied on the dorsum on days 1 and 15 was evaluated in 90 dogs from a shelter, naturally infested with sarcoptes scabiei. this very practical form of treatment was successful in eradicating scabies from this shelter.19979187806
endectocidal efficacies of doramectin in naturally parasitized pigs.the studies reported here were conducted to investigate the effectiveness of doramectin, given intramuscularly at the rate of 300 micrograms kg-1 of bodyweight, in the treatment of naturally acquired porcine nematodosis and acariasis. twenty pigs demonstrated to be naturally infected with pulmonary and gastrointestinal nematodes were used in one control study, and 22 pigs demonstrated to be naturally parasitized with sarcoptes scabiei var. suis were used in a second study. in both studies, anima ...19979195716
epiluminescence microscopy. a new approach to in vivo detection of sarcoptes scabiei.the usual methods of scabies diagnosis include microscopic identification of the mites and their eggs and feces in skin scrapings. in many cases, the results of microscopic examination can be negative owing to the low number of parasites present in the cornified layer. epiluminescence microscopy (elm) is an in vivo technique that allows a detailed inspection of the skin, from the surface to the superficial papillary dermis. this is where the scabies mite lives. in this study, we evaluate the app ...19979197830
serodiagnosis of sarcoptic mange in pigs.a serodiagnostic test (elisa) for detecting antibodies to sarcoptes scabiei in the sera of pigs was evaluated. the elisa results from 221 specific pathogen-free pigs of three different age categories were used to establish a cut-off value for the assay. background optical density values differed significantly between the three groups, the sows having the highest values. the mean + 3 sd of their values was chosen as the cut-off. four farrow-to-finish herds of pigs with sarcoptic mange were invest ...19979248016
skin test and radioallergosorbent test characteristics of scabietic patients.the scabies mite sarcoptes scabiei and the dermatophagoides house dust mites (hdm) are related phylogenetically and are the sources of several cross-reactive antigens. the purpose of this study was to investigate the immune response to s. scabiei and hdm in scabietic patients. skin test sensitivity and serum ige to both s. scabiei and hdm were determined for patients who had or previously had confirmed ordinary scabies. a retrospective group included nine subjects who had received successful tre ...19979288815
our man in havana. 19979329903
the spread of porcine sarcoptic mange during the fattening period revealed by development of antibodies to sarcoptes scabiei.using an indirect elisa based on a whole body homogenate of sarcoptes scabiei var vulpes, the development of serum antibodies to s. scabiei var suis during the fattening period was studied in two herds, purchasing fatteners and performing age segregated production systems. all the pigs in one of the herds were treated with ivermectin on the same day within a week after arrival, while no precautions were made to prevent sarcoptic mange in the other herd. in both herds, a transient immune response ...19979477518
[transitory acantholytic dermatosis (grover's disease) in sarcoptic scabies infection].an eighty-two year old patient had scabies and transient acantholytic dermatosis (tad, grover's disease) at the same time. persistent itching papules after lindane therapy finally led us to the microscopic diagnosis of tad. different trigger mechanisms can apparently induce the typical acantholysis. in addition to solar radiation, tumors and tumor therapy-dependent conditions, cutaneous infections have been implicated reports (demodex folliculorum, malassezia furfur) as causes of tad. this may b ...19979486364
[epidemiological study of pediculosis capitis and scabies in schoolchildren from antofagasta, chile, 1995].in order to contribute to a better knowledge of the pediculosis capitis and scabies during march-december 1995, 1122 primary schoolchildren under 14 years of age in the city-port of antofagasta in northern chile (20 degrees south lat.), were examined. a total of 285 (25.4%) were found to be infested with pediculus humanus capitis and only 20 (1.8%) with sarcoptes scabiei. in general the rates of infestation to both ectoparasitic diseases were higher in groups of younger schoolchildren, also high ...19979497538
'burrow-trucut'--a method for harvesting scabietic burrows. 19979529570
control of sheep scab. 19979248021
epizootiology of sarcoptic mange in a population of cantabrian chamois (rupicapra pyrenaica parva) in northwestern spain.in may of 1993, an epizootic of sarcoptic mange (sarcoptes scabiei) was detected in the chamois (rupicapra pyrenaica parva) population of the cantabrian mountains in northwestern spain. the epizootic initially spread across an area inhabited by some 1600 chamois. mortality was lower than reported for other populations of ungulates. the maximum number of animals were affected from february to may. four red deer (cervus elaphus) and a roe deer (capreolus capreolus), were diagnosed with sarcoptic m ...19979477502
a dna fingerprinting system for the ectoparasite sarcoptes scabiei.we describe multiple hypervariable microsatellites that will provide a highly informative genetic marker system for the sarcoptid mite sarcoptes scabiei. eighteen positive clones containing the highly repetitive sequence (ga)n were isolated from a partial genomic library of s. scabiei. ten of these clones were characterised by sequencing and primers were designed from the unique sequences flanking eight microsatellite loci. genomic dna was subsequently extracted from individual mites and the rep ...19979106192
[francesco redi and the birth of experimental parasitology].francesco redi (1626-1697) born in arezzo (tuscany, italy), an encyclopedic mind simultaneously naturalist, physician and poet is the founder of scientific and experimental parasitology by his works published in 1668 and 1684. in the first he showed the impossibility of spontaneous generation of insects (flies) and in the second are described over hundred species of parasites (helminths, mites, insects) from vertebrates and invertebrates with excellent illustrations. he has also recommended vari ...199711625103
norwegian scabies in a patient with acquired immunodeficiency syndrome.we report the case of a 42-year-old man with symptomatic hiv infection (c3 cdc stage) who presented widespread hyperkeratotic skin lesions diagnosed as norwegian scabies. the cd4 count was 87 cells/mm3. the patient has been the source of a nosocomial outbreak (20 individuals affected). he was treated successfully with combined topical treatment (permethrin 5% cream plus keratolytic agents) and oral ivermectin.19989812044
ivermectin for sarcoptes scabiei hyperinfestation.crusted (norwegian) scabies is an unusual variant of scabies caused by hyperinfestation with sarcoptes scabiei. it has high morbidity, and secondary bacterial skin sepsis may result in life-threatening bacteremia. an open label study of oral ivermectin was carried out in patients with crusted scabies refractory to topical therapy.19989531662
evaluation of the prevalence of sarcoptic mange in slaughtered fattening pigs in southeastern spain.in this study the prevalence of sarcoptic mange in fattening pigs in murcia, southeastern spain was investigated. results showed that 37% of the 1318 slaughtered pigs examined were positive for sarcoptes scabiei var. suis. skin lesions potentially attributable to this mite were present in 92.80% of animals, but the parasite could be detected in only 38.60% of them. the condition of the ear (clean/dirty) was not a defining characteristic for the diagnosis of this swine disease. a sucrose flotatio ...19989615954
scabies: revisit in a depressed economy.scabies is a highly contagious disease of the skin caused by an ectoparasite arthropod called sarcoptes scabiei var hominis. it has a world-wide distribution and affects all ages with no specific gender predisposition. scabies is of public health interest because certain environment factors such as overcrowding, poor hygiene, delayed treatment of primary cases and lack of public enlightenment are conducive to its spread. however, prompt and adequate therapy is rewarding and prevents spread.19989631110
findings in vivo of sarcoptes scabiei with incident light microscopy.parasites, especially sarcoptes scabiei, may represent a difficult diagnostic problem. in many cases, the results of the usual methods for the diagnosis of scabies, such as microscopic identification, can be negative owing to the small number of parasites present in the cornified layer. moreover, tape stripping or removal of mites with a needle is difficult and sometimes painful, and therefore, not well accepted. we have evaluated the applicability and usefulness of epiluminescence microscopy, a ...19989649720
sarcoptic mange in wombats. 19989673765
current distribution of sarcoptic mange in wombats.to determine the distribution and prevalence of sarcoptic mange in wombats, particularly the common wombat (vombatus ursinus).19989673766
responses of red foxes to first and second infection with sarcoptes scabiei.the clinical response of red foxes (vulpes vulpes) to the mange mite, sarcoptes scabiei, was characterized by infection of five, 4-mo-old red foxes with s. scabiei originally isolated from a wild red fox. the infected foxes and three uninfected control foxes were monitored with weekly complete blood counts and biweekly serum chemistry profiles, hypersensitivity tests, and evaluation of skin biopsies. after 7 wk, the foxes were treated and held free of infection for 2 mo. six foxes, three previou ...19989706571
[continuous serologic study and sanitation inspection of sarcoptes scabiei var. suis infection: preliminary results].pig mange was investigated serologically with elisa using chekit sarcoptest. the test consists of a homogenized antigen of sarcoptes scabiei var. vulpes. a total of 356 sows sera samples were collected from 16 mange free breeding units and 19 units with clinical manifestation of mange infestation. the specificity of the test was 99.34% and the mean sensitivity value was 62%. this test will allow in the future not only the rapid and certain diagnosis of pig mange but also the screening of the pig ...19989863358
efficacy and tolerance of oral ivermectin in scabies.the aim of this open-label study was to investigate the therapeutic effect and adverse reactions of oral ivermectin in scabies patients.19989883437
lice and scabies. myths and reality.scabies mites are only distantly related to human lice. nevertheless, the two groups have much in common as regards to structure and life-style. these similarities result from the two groups using parallel adaptations in order to solve some of the problems of being parasites. understanding these adaptations may help us give better advice.19989891692
the relation between scabies and hypersensitivity to antigens of house dust mites and storage mites.twenty five non-atopic scabietic patients were examined to estimate their reaction to crude house dust mite dermatophagoides farinae (d. farinae) and storage mite tyrophagus putrescentia (t. putrescentiae) antigens. skin prick testing (spt) by extracts of both mites antigens showed significant higher positive results in scabietics when compared to non-scabietic control subjects. moreover, 60% and 56% of scabietic patients showed positive levels of specific anti-d. farinae and t. putrescentia ige ...19989914700
treatment of scabies with ivermectin.the authors report six new cases of patients suffering from severe infestation with the mite sarcoptes scabiei, treated with ivermectin, currently the only oral therapy available for this disease. each patient received 200 mug/kg of ivermectin, taken as single dose. no topical therapy was undertaken, except for topical treatment with emollient, as needed. the drug was very effective in all cases, easy to use, safe, and particularly useful in those patients with secondary eczematisation and escor ...199910066955
the efficacy of simplified eradication strategies against sarcoptic mange mite infections in swine herds monitored by an elisa.eradication programmes directed against sarcoptes scabiei var. suis, performed without any disinfection of the environment, were compared to an eradication programme including a simultaneous environmental disinfection. the performance of such programmes would be facilitated considerably if environmental disinfection could be avoided. the trial was conducted in four conventional piglet-producing herds designated a-d. all herds suffered from a subclinical but persistent infection with the sarcopti ...199910190868
[scabies]. 199910201273
efficacy of a pour-on formulation of doramectin against lice, mites, and grubs of cattle.to determine effectiveness of a pour-on formulation of doramectin against damalinia bovis, haematopinus eurysternus, linognathus vituli, solenopotes capillatus, chorioptes bovis, sarcoptes scabiei, hypoderma bovis, and hypoderma lineatum.199910211679
persistent efficacy of doramectin and ivermectin against experimental infestations of sarcoptes scabiei var. suis in swine.two studies were performed to compare the persistent efficacy of doramectin and ivermectin in swine experimentally infested with sarcoptes scabiei var. suis. in the study 1, 84 pigs were treated with doramectin, ivermectin, or saline solution on day 0. pigs were then challenged with mites on days 0, 7, 14, 21, 28, 35, or 42. weekly evaluations were performed for 5 weeks following challenge with mites. weekly evaluations included physical examination for clinical signs of sarcoptic mange and coll ...199910223351
dermacase. crusted norwegian scabies. 199910386207
arthropod parasites of nubian ibexes (capra ibex nubiana) and gazelles (gazella gazella) in israel.in a 20-year survey the following ectoparasites were collected from nubian ibexes: larvae of an unidentified oestrus sp. collected from the nasal cavities, sinuses and horns, hippoboscid flies (lipoptena chalcomelaena) specific to the nubian ibex, blood sucking lice (linognathus africanus) and unidentified biting lice (damalinia sp.). ibexes were severely infested with the cattle tick, boophilus annulatus; a few hyalomma anatolicum excavatum ticks were also collected. in five ibexes kept in two ...199910392972
crusted (norwegian) scabies induced by use of topical corticosteroids and treated successfully with ivermectin.crusted scabies is mainly observed in children with immunosuppression or mental illness. treatment is very difficult, and relapse is frequent after topical scabicidal therapy. we describe a case of crusted scabies, induced by long-term application of a topical corticosteroid, relapsing after topical treatment and dramatically improved by ivermectin. we suggest that ivermectin is a safe and effective alternative therapy for the treatment of severe sarcoptes scabiei infestation in children unrespo ...199910393619
molecular analyses suggest monospecificity of the genus sarcoptes (acari: sarcoptidae).to clarify the taxonomic status of mites of the genus sarcoptes, the second internal transcribed spacer (its-2) of the rrna gene, as well as phenotypic characters, were investigated in 23 isolates from nine host species in four continents. phenotypic differences among isolates were observed, but the range of variation within each isolate precluded the differentiation of individual mites. genotypically, there was no delimitation between distinct genotypic groups and no correlation with host speci ...199910404272
[farm animals as disease vectors of parasitic epizoonoses and zoophilic dermatophytes and their importance in dermatology].different pest arthropods and dermatophytes occurring primarily in farm animals may be transmissible to man and produce human dermatoses. the movement and cutaneous penetration habits of external parasites often cause crusted papules, severe itching and dermatitis or may damage their hosts by blood-sucking or by sensitizing them to their saliva. furthermore different dermatophytes should be considered a possible cause of human skin lesions. farm animals (cattle, pig, poultry, and rabbit) can tra ...199910501677
[scabies in infants--problems in differential diagnosis].scabies is very often parasites dermatosis. diagnostic problems are not rare considering the fact that the clinical picture of scabies in infant population is different compared to the adult population. the scabies that is untreated or non-adequately treated has a long course followed by complications. in hospital in tuzla in a period 1995-1997 we have done retrospective study which included 64 infants with scabies followed with complications. skin changes have appeared approximately 2-6 months ...199910758763
[pseudo-scabies transmitted by red fox].pseudoscabies, i.e. infestation of human skin with animal mites may occasionally occur and should be considered in the differential diagnosis of pruritic and papular skin disease. we report here on a 52-year-old woman with pseudoscabies or canine scabies (sarcoptes scabiei var. canis), transmitted by indirect contact with a red fox in the urban area of berlin. red foxes may live in unhabited areas of metropolitan large cities, i.e. in garages, car wrecks and cellars. full remission of the prolon ...199910097956
human scabies of wombat origin. 199910561798
distribution of life cycle stages of sarcoptes scabiei var wombati and effects of severe mange on common wombats in victoria.seven female and three male common wombats (vombatus ursinus) collected from forested areas of victoria (australia) over a 10 mo period, 10 april 1997 to 22 february 1998 had at least 30% of their skin affected by severe hyperkeratotic sarcoptic mange. mangy wombats were grazing during the day, could be readily approached, were in poor body condition, and lacked subcutaneous fat. the anterolateral surface of the body was most heavily parasitised with sarcoptes scabiei var wombati followed by the ...199910574522
sarcoptic mange in spanish ibex from spain.the spanish ibex (capra pyrenaica hispanica) population of the "sierras de cazorla, segura y las villas" nature park (spain) was isolated as the result of a severe epidemic of sarcoptic mange. in this context, the dynamic characteristics of the disease were analyzed in a wild group consisting of 35 animals from the beginning of the epizootic (when the mating period started) to the extinction of the population due to mange. monthly tracking permitted the sequential characterization of the patholo ...199910574523
national guideline for the management of scabies. clinical effectiveness group (association of genitourinary medicine and the medical society for the study of venereal diseases). 199910616390
a gallic affair: the case of the missing itch-mite in french medicine in the early nineteenth century. 199910885132
[serologic herd study and sanitation inspection of sarcoptes scabiei var. suis infection: a seroepidemiologic study in mange-free and chronically-infected facilities].sera from 88 pigs chronically infected with sarcoptes scabiei var.suis were tested in order to evaluate the course of antibody titer with the chekit sarcoptest using homogenized sarcoptes scabiei var.vulpes as antigen. the results were compared with sera of pigs from mange free breeding units. the results of this study show that sera from piglets less than two week old and gilts older than eight months can be used. no positive titers were observed in animals between five weeks and four months of ...199910624151
oral ivermectin in the treatment of scabies.one hundred and twenty scabietic patients attending the outpatient clinic of the department of dermatology, mansoura university hospital, voluntarily participated in this uncontrolled, open label study to evaluate ivermectin 20 microg/kg as a scabietic after they had given their consent. the scabietic subjects included in this study were otherwise healthy, mentally competent, aged more than 18 years, and used no topical antiscabietic treatment in the week before ivermectin treatment, or during t ...199910632775
eradication of sarcoptic mange from a belgian pig breeding farm with a combination of injectable and in-feed ivermectin.sarcoptes scabiei var suis was eradicated from a belgian pig farm by using a combination of injections of ivermectin and ivermectin in the feed. the detection of mites in ear scrapings, and calculations of an average dermatitis score and a scratching index were used to evaluate the mange status of the pigs before and after the treatment. before the treatment 28 per cent of ear scrapings of finishers were positive for the presence of mites, their average dermatitis score (ads) was 0.92 and their ...199910972109
crusted scabies: a molecular analysis of sarcoptes scabiei variety hominis populations from patients with repeated infestations.crusted scabies is a severe debilitating disease due to hyperinfestation with the ectoparasite sarcoptes scabiei. treatment protocols include oral ivermectin and topical scabicides. after single-dose ivermectin, there may be early recrudescence, whereas after 3 doses at 14-day intervals, there is an apparent cure. however, such patients often present again after 6-12 months. to clarify the biology of recurrence, we studied genetic markers in sequential populations of s. scabiei mites from treate ...199910524967
[comment on the work of e. kösler: "transitory acantholytic dermatosis (grover's disease) with sarcoptes scabiei infection". hautarzt (1997) 48:915-7]. 199910354927
genetically distinct dog-derived and human-derived sarcoptes scabiei in scabies-endemic communities in northern australia.overcrowding is a significant factor contributing to endemic infection with sarcoptes scabiei in human and animal populations. however, since scabies mites from different host species are indistinguishable morphologically, it is unclear whether people can be infected from scabies-infested animals. molecular fingerprinting was done using three s. scabiei-specific single locus hypervariable microsatellite markers, with a combined total of 70 known alleles. multilocus analysis of 712 scabies mites ...199910548286
the efficacy of selamectin in the treatment of naturally acquired infestations of sarcoptes scabiei on dogs.selamectin, a novel avermectin, was evaluated for its effect on naturally occurring infestations of sarcoptes scabiei in 42 dogs. in two controlled and masked laboratory studies conducted in the usa and italy, infested dogs received treatment with either selamectin (6mgkg(-1); range: 6-12mgkg(-1)) or the vehicle only (negative control). treatments were administered topically to the skin on each animal's back at the base of the neck in front of the scapulae. study day 0 was defined as the first d ...200010940528
serum antibody to sarcoptes scabiei and house dust mite prior to and during infestation with s. scabiei.in this study, serum antibodies to sarcoptes scabiei var. canis (ss), dermatophagoides farinae (df), and d. pteronyssinus (dp) were determined in 19 healthy, random-source dogs prior to infestation with scabies then again during a primary infestation, cure and challenge infestation with scabies. prior to scabies infestation, serum of 11 dogs contained faintly detectable amounts of ige and/or igg to proteins in ss extract, probably resulting from sensitization to dust mites that share cross-react ...200010856817
experimental quantification of the transmission of sarcoptes scabiei var. suis among finishing pigs.in this study, the rate of s. scabiei var. suis transmission among finishing pigs was quantified in a contact transmission experiment. forty piglets originating from a mange free farrow-to-finish herd were randomly allocated to three groups and one s. scabiei var. suis infested finishing pig was subsequently added to each of these groups. after 35 days, the three seeder pigs were removed from the groups and the remaining 40 pigs were re-allocated to five pens. ear scrapings, to be examined for m ...200011027861
[diet food and ectoparasites play an important role in dermatology]. 200011109277
elimination of sarcoptes scabiei in pig herds by single or double administrations of an avermectin.attempts to eliminate sarcoptes scabiei var. suis were made in 2 piglet producing herds by intramuscular injections with doramectin (dectomax, pfizer inc., new york, usa). no hygienic measures of the environments were undertaken. in herd a, all animals were treated twice at a 14-day interval. theoretically it should be possible to eliminate the mite with a single injection and therefore the animals in herd b were treated only once. the results were measured by attempts to demonstrate s. scabiei ...200011126572
the prevalence of internal and external parasites in pigs of different ages and sexes in southeast district, botswana.botswana imports most pig-based products from neighbouring countries. pig farming is limited by, among other things, the negative effect of parasites and diseases on production. the object of this study was to determine the prevalence of ecto- and endoparasites in pigs of different ages and sexes in the southeast district of botswana. thirty-nine pigs were sampled for endoparasites and 19 for ectoparasites during a period of 2 1/2 months. of all the pigs sampled, 54,55% were infected with ascari ...200011131123
production performance and pruritic behaviour of pigs naturally infected by sarcoptes scabiei var. suis in a contact transmission experiment.reports on the effects of mange on the production performance of pigs are conflicting. so far, studies have used experimental infections, by depositing encrusted lesions from chronically infected pigs into the ears of experimental pigs. however, this is a poor representation of what happens under natural field conditions. the purpose of our study was to quantify the effects of sarcoptic mange on production performance and pruritus in pigs that were infected by contact with s. scabiei var. suis-i ...200010952444
efficacy of an abamectin in-feed preparation against mites in pigs. 200010955896
effects of sarcoptic mange on serum proteins and immunoglobulin g levels in chamois (rupicapra pyrenaica) and spanish ibex (capra pyrenaica).three groups of chamois (rupicapra pyrenaica) and three groups of spanish ibex (capra pyrenaica) were established to study the effects of sarcoptic mange on serum proteins and immunoglobulin g (igg) levels. the first group of chamois consisted of 22 healthy pyrenean chamois (r. pyrenaica pyrenaica) from a non-infested area, the second group consisted of 20 healthy cantabrian chamois (r. p. parva) from an area where sarcoptic mange has been reported since 1994 and the third group consisted of 16 ...200010714470
sero-prevalence of granulocytic ehrlichia spp. and borrelia burgdorferi sensu lato in swedish dogs 1991-94.in sweden, 2 tick-borne zoonotic diseases, granulocytic ehrlichiosis and borreliosis, are frequently diagnosed in dogs, using serological assays. the aims of this study were to determine the sero-prevalences of antibodies to ehrlichia spp. and borrelia burgdorferi sensu lato during 1991-94 in dogs, not clinically suspected to be infected with either of the 2 agents. samples (n = 611) were selected from a serum bank using a systematic sampling strategy, stratified across the 4-y period. the store ...200010716072
validation of elisas for the detection of antibodies to sarcoptes scabiei in pigs.an enzyme-linked immunosorbent assay (elisa) was developed for the detection of antibodies to sarcoptes scabiei. this 'animal health service'-elisa (ahs-elisa) was compared with a commercial test (checkit(r) sarcoptest) using experimental and field sera. the experimental study was a contact infestation experiment. eighty piglets were randomly divided between the experimental and control group. after introduction of three sarcoptes scabiei var. suis infested pigs in the experimental group, both g ...200010729649
studies in vitro on the relative efficacy of current acaricides for sarcoptes scabiei var. hominis.resistance of sarcoptes scabiei to various topical therapies has been described, but clinical assessment of treatment failure is problematic and in-vitro assays are generally not available. we describe a simple in-vitro analysis used to evaluate the relative efficacy of a range of topical, oral, and herbal treatments available in australia for the treatment of scabies. s. scabiei var. hominis mites were collected from skin scrapings obtained from 7 crusted scabies patients over a period of 2 yea ...200010748911
case report: teledermatology and epiluminescence microscopy for the diagnosis of scabies.we wish to share images from a patient seen in our teledermatology program. due to the absence of on-site dermatology services at the togus, maine, department of veterans affairs, and associated community clinics for veterans in aroostook, bangor, calais, and rumford, we created a program to provide dermatologic expertise from providence, rhode island. patients referred for this service were evaluated by a nurse practitioner, who obtained a history, performed a physical examination, and captured ...200010916694
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