Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| hepatitis a virus among captive panamanian owl monkeys. | 1981 | 6118799 | |
| relapsing hepatitis associated with hepatitis a virus. | 1982 | 6123879 | |
| [radioimmunological determination of hav and anti-hav iga in the feces of patients with acute type-a hepatitis]. | 58 fecal specimens from 14 patients (10 hepatitis a, 2 hepatitis b and 2 infectious mononucleosis) were tested for the hepatitis a virus (hav) and iga anti-hav by micro-solid-phase-radioimmunoassay. only patients with hepatitis a were positive for hav and/or iga anti-hav. in the first days of the disease we found hav in the feces of 4 patients but it was never present after the sixth day. in all hepatitis a we found iga anti-hav in at least one fecal specimen and the titer of the antibodies incr ... | 1982 | 6100166 |
| serological markers of hepatitis a and b virus infection in university students. | serological markers of hepatitis a and b virus infection were determined by radioimmunoassay in 162 university students. antibody to hepatitis b e antigen (anti-hbe) was demonstrated in 11 of 15 students positive for both antibody to hepatitis b e antigen (hbsag) and antibody to hepatitis b core antigen (anti-hbc). the presence of anti-hbc alone seemed to denote previous hepatitis b virus infection. antibody to hepatitis a virus was demonstrated only in 3%. study of 23 stored hbsag-positive sera ... | 1982 | 6294917 |
| antibody to hepatitis a and hemodialysis. | antibody to hepatitis a virus (anti-hav) was surveyed in 469 patients from 20 of 31 michigan hemodialysis units, during spring 1978. the mean point prevalence of anti-hav was 59.5% and within the 20 individual units ranged from zero to 100%. for the entire survey population, the point prevalence of anti-hav was significantly greater with increasing age, among blacks, and in individuals with hypertension as their underlying renal disease. anti-hav was independent of sex, duration of dialysis, or ... | 1982 | 6293303 |
| use of conventional and igm-specific radioimmunoassays for anti-hepatitis a antibody in an outbreak of hepatitis a. | during a common source outbreak of hepatitis a, we studied the characteristics and utility of commercially available radioimmunoassays for total and igm-specific antibody to hepatitis a virus. igm hepatitis a antibody was detectable in all serum specimens obtained up to 119 days following onset from the seven persons with hepatitis a, and as long as 347 days in one person. acute infection could also be documented by a four-fold or greater increase in titers of hepatitis a antibody, although as l ... | 1982 | 6291386 |
| detection of hepatitis a antigen in human liver. | for the first time, hepatitis a viral antigen (haag) was shown in liver biopsy tissue from a patient in the acute phase of hepatitis type a by light and electron microscopy, using the peroxidase-antibody technique. under light microscopy, the staining for haag appeared as a fine, granular reaction product, scattered throughout the cytoplasm of hepatocytes and sinusoidal lining cells. standard thin-section electron microscopy revealed virus-like particles, 24 to 27 nm in diameter, in cytoplasmic ... | 1982 | 6281190 |
| hepatitis virus vaccines: present status. | during the past decade there has been extraordinary progress toward the development of vaccines for the prevention of type a and type b hepatitis. the successful propagation of hepatitis a virus in cell culture in 1979 was followed by the preparation of experimental live attenuated hepatitis a vaccines that have been shown to induce antibody in marmosets and chimpanzees and protect immunized marmosets against challenge with hepatitis a virus. the first human immunization trials will begin in mid ... | 1982 | 6295013 |
| survival of hepatitis a virus in feces after drying and storage for 1 month. | hepatitis a virus in feces remained viable after being dried and then stored at 25 degrees c and 42% relative humidity for 30 days, as evidenced by infection of two marmosets inoculated with 1 ml of the treated fecal material. the virus was excreted in stool specimens from these animals, and seroconversion to antibody to hepatitis a virus occurred 28 and 35 days post-inoculation. | 1982 | 6296198 |
| the spread of hepatitis a virus in connection with hepatitis cases in children's communities. | in order to investigate the characteristics of hepatitis a virus excretion, 372 children in semi-closed day-care centres were examined at the time of the seasonal increase in hepatitis incidence. enzyme immunoassay and immune electron microscopy were used to detect virus in faeces. ten communities were surveyed and, for the purposes of this paper, were divided into four groups on the basis of the observed pattern of virus excretion. the first group consisted of 4 communities with one hepatitis c ... | 1982 | 6286164 |
| an outbreak of infectious hepatitis investigated using radioimmunoassays for hepatitis a virus antibody. | an outbreak of suspected infectious hepatitis in a primary school was investigated using sensitive diagnostic methods for hepatitis a. a total of 116 sera from children were tested for the presence of both igm and igg antibodies to hepatitis a (hav). the results were compared to those obtained for samples from a control school. igg antibodies were present in 45% and 10% of the children in the outbreak and control schools respectively. | 1982 | 6278018 |
| demonstration of a single antigen-antibody system in 26 patients with non-a, non-b viral hepatitis. | 26 patients with viral hepatitis were selected on the basis of negative responses to serological tests for hepatitis b virus and hepatitis a virus infections. the illness was acute in 19 patients and chronic persistent in the remaining 7. immunodiffusion tests showed a single antigen-antibody system in the sera of all 26 patients. each patient had at least one serum sample positive for antigen or antibody. in 1 post-transfusion case, the corresponding immunological marker was found in the donor. ... | 1982 | 6181364 |
| hepatitis a virus (hav) cultivation on the cercopithecus kidney cell line (rc37). | 1982 | 6314917 | |
| in vitro processing of avian oncovirus precursor polypeptide pr76gag by virion protein p15. | in vitro cleavage by p15 virion protein of the primary translation product of the avian oncovirus gag gene, the precursor polypeptide pr76gag, was studied in kinetic experiments. nondenatured 35s-methionine-labelled pr76gag, which was synthetized in reticulocyte lysate programmed by genomic amv-rna was used as a substrate, pure native p15 (amv) as a protease. reaction conditions were optimal for in vitro protein synthesis. composition of the cleavage products was estimated by immune precipitatio ... | 1982 | 6286372 |
| [the prevalence of antibody to hepatitis a virus in different age groups of hokkaido inhabitants (author's transl)]. | serum specimens drawn at random from hokkaido inhabitants were tested for antibody to the hepatitis a virus (anti-hav) by radioimmunoassay. the prevalence in different age groups was as follows, cord blood and newborn infants 44.4%, under one year 0%, 1-9 years 5.3%, 10-19 years 0%, 20-29 years 9.1%, 30-39 years 80%, 40-49 years 90%, and over 50 years 100%. this survey confirmed that antibody against hav could pass through placenta and hav had been very common virus by the 1950's in hokkaido. | 1982 | 6281151 |
| [hepatitis b and hepatitis a markers in 33 cases of acute hepatitis b surface antigen-negative, hepatitis a virus antibody-positive viral hepatitis. importance of immune complexes]. | the authors have looked for the markers of hbv by r.i.a. method (hbsag, anti hbsag, hbeag, anti hbeag, anti hbcag), of hav (by measurement on two samples of havab or by measurement of havab igm), the immune-complexes (i.c.c.) by c1q solid-phase binding assay method with e.l.i.s.a. with determination after division i.c.c. of hbsag by r.i.a. method in 33 cases of hbsag negative acute viral hepatitis. the 9% (3 cases) were hav acute hepatitis, the 42,4% (14 cases) no a no b acute hepatitis, the 36, ... | 1982 | 6281689 |
| [concentration of the hepatitis a virus on artificial and natural sorbents]. | 1982 | 6284591 | |
| a large outbreak of hepatitis a in a day-care center: association with non-toilet-trained children and persistence of igm antibody to hepatitis a virus. | in early summer, 1979, a large outbreak of hepatitis a occurred in an oklahoma day-care center. a total of 41 cases were confirmed, all in adults. of the 115 non-employee households represented by children in the center, 19 households (16.5%) had one or more cases of hepatitis. hepatitis occurred in 29% of the households with at least one non-toilet-trained child, compared to 2% of the households without such a child (p = 0.00004). at least four (15%) of 27 center employees had hepatitis. of 26 ... | 1982 | 6278926 |
| increased risk of infection with hepatitis a and b viruses in men with a history of syphilis: relation to sexual contacts. | serum samples from 269 men with at least one episode of syphilis were tested for the presence of markers of hepatitis a and b viruses. the patients were divided into three groups: 177 homosexual men, 35 heterosexual men, and 57 men with unknown sexual contacts. the incidence of hepatitis b surface antigen or its antibody (anti-hbs) was three times greater in the homosexual men (67%) than in the men with unknown sexual contacts (25%) and the heterosexual men (23%). the incidence of anti-hbs incre ... | 1982 | 6274966 |
| excretion of hepatitis a virus in the stools of hospitalized hepatitis patients. | a study was carried out to determine whether hepatitis a virus (hav) can be detected in the stools of patients hospitalized for hav infection. acute phase samples of whole blood and stool, as well as completed questionnaires, were obtained from 31 patients hospitalized at any of 13 hospitals in the phoenix metropolitan area. blood specimens were tested for hepatitis b surface antigen (hbsag), igg antibody to hav (igg anti-hav), and igm antibody to hav (igm anti-hav). stools were tested for hav b ... | 1982 | 6279780 |
| foodborne hepatitis a at a family reunion use of igm-specific hepatitis a serologic testing. | a cluster of cases of hepatitis a that occurred among 46 participants in a family reunion in utah in august 1980 was investigated with epidemiologic and serologic techniques. no index patient with clinical illness had been present at the reunion. twenty-three cases of hepatitis a were ultimately identified; 14 developed clinical hepatitis. immunoglobulin m-specific hepatitis a virus antibody testing identified nine recently infected asymptomatic subjects. eight additional individuals had serolog ... | 1982 | 6282115 |
| purification of acute phase anti-hepatitis a virus (hav) igm and development of an igm solid-phase radioimmunoassay for the detection of hav. | a simple two-step procedure for the purification of igm from acute phase hepatitis a infected chimpanzee serum has been developed. the procedure involves the precipitation of the euglobulin fraction with boric acid and the fractionation of the resuspended material on sephacryl s-300 (pharmacia fine chemicals, piscataway, nj). the purified igm was used to develop a solid-phase radioimmunoassay (spria) in which igm was used as capture antibody and iodinated igm was used as a probe. this assay was ... | 1982 | 6286776 |
| dissociation of hepatitis a virus antigen-anti-hav antibody complexes by 2-mercaptoethanol and dithiothreitol. | intravenous inoculation of two marmosets and one chimpanzee with hepatitis a virus (hav) resulted in the replication of virus in liver, excretion of hav particles in stool, and the appearance of circulating antibodies specific for hepatitis a. the development of an early antibody response in the chimpanzee and in one of the two infected marmosets was shown to interfere with the serologic detection of hav antigen (hav ag) in homogenates of acute phase liver tissue obtained from these animals. tre ... | 1982 | 6286866 |
| [cultivation of hepatitis a virus in tissue culture: the possibility of virus production for vaccines and testing, for the diagnosis of infection in patients and for the testing of disinfectants]. | 1982 | 6287377 | |
| presumable non-a, non-b hepatitis in hemodialysis. | hepatitis a and b markers, igm-anti-cmv and -ebv were determined in 154 dialysis patients, 118 relatives of patients and 42 members of the staff. episodes of elevated transaminases were investigated for presumable non-a, non-b hepatitis as well as secondary infections among relatives. --the cumulative frequency of hbv markers was 71% in center dialysis patients, 63% in home dialysis patients, 50% in staff and 19% in relatives. the frequency of hbv markers increased with duration of dialysis trea ... | 1982 | 6287760 |
| failure of guanidine and 2-(alpha-hydroxybenzyl)benzimidazole to inhibit replication of hepatitis a virus in vitro. | replication of hepatitis a virus (hav) in the human hepatoma-derived plc/prf/5 cell line was neither inhibited in the presence of various concentrations of guanidine or d-2-(alpha-hydroxybenzyl)benzimidazole (d-hbb), nor were the two chemicals effective in combination. under identical conditions, however, replication of poliovirus type 1 was inhibited. tracer experiments with radiolabelled guanidine and d-hbb also furnished no evidence that the two antiviral substances were metabolized gradually ... | 1982 | 6288846 |
| antibody to hepatitis a virus in healthy nigerians. | two hundred and fifty nigerians (175 male and 75 female), whose ages ranged from 5 to 70 years, were surveyed for the presence of antibody to hepatitis a virus (anti-hav). the prevalence was determined to be 82 percent. the rates were highest in blood donors (90 percent) and hospital workers (91.4 percent) and lowest in children under the age of 10 (25 percent). the prevalence rates were not related to socioeconomic groups, previous exposure, jaundice, or sex. the study confirms that hav infecti ... | 1982 | 6288969 |
| [determination of hepatitis a virus in the feces of patients in the dynamics of the infectious process]. | excretion of hepatitis a virus (hav) in the time course of the infectious process is described. among 197 fecal specimens collected from 45 patients hav was found in 40 (20.5%); in 51% of the patients the virus was isolated in the 1st week of the icteric period, in 25% in the 2nd week and in 4% in the 3rd week. the buoyant density in cesium chloride gradient of virus specimens obtained on the 1st-2nd day of jaundice was represented by one peak of 1.30-1.35 g/cm3, whereas the material collected a ... | 1982 | 6289528 |
| [detection of igm and igg antibodies to hepatitis a virus by reversed passive hemagglutination inhibition test]. | 1982 | 6290007 | |
| transmission of hepatitis a virus among recently captured panamanian owl monkeys. | the presence of antibody to hepatitis a virus (anti-hav) in 60% of procured owl monkeys (aotus trivirgatus) held within the united states prompted a study of recently captured a trivirgatus in panama. only 2 of 145 newly captured monkeys, but all of 35 a trivirgatus held within a colony for over 100 days, were found to have anti-hav. of 41 sero-negative, newly captured monkeys followed prospectively, 25 became infected with hepatitis a virus (hav) as evidenced by seroconversion or demonstration ... | 1982 | 6290600 |
| hepatitis a virus infection of hbsag-producing hepatocellular carcinomas in athymic mice. | 1982 | 6297712 | |
| [antibodies to the hepatitis a virus in the healthy population of moscow]. | serum specimens collected from 1002 persons in moscow were tested for the presence of antibodies to hepatitis a virus (anti-hav antibodies) by solid-phase enzyme immunoassay. the prevalence of these antibodies increased progressively with age from 10% in children aged 5-9 years to over 90% in the age groups of 40-49 years and over, the 50% immunity level being established at the age of 18 years. 79% of infants under 1 year were found to be immune, which was obviously due to the placental transfe ... | 1982 | 6285646 |
| seroepidemiology of infection with hepatitis a virus and hepatitis b virus in the seychelles. | a batch of 417 serum samples obtained from native-born subjects were tested for the presence of hepatitis b surface antigen (hbsag) and corresponding antibody (anti-hbs), by enzyme-linked immunosorbent assay (elisa); and antibodies to hepatitis b core antigen (anti-hbc), e-antigen (anti-hbe), and hepatitis a virus (anti-hav), by radioimmunoassay (ria). hbsag was found in only two of the 417 subjects studied. anti-hbs was detected in 112 samples (26.8%), anti-hbc in 114 (27.3%) and anti-hbe in 31 ... | 1982 | 6285695 |
| classification of hepatitis a virus as enterovirus type 72 and of hepatitis b virus as hepadnavirus type 1. | 1982 | 6292125 | |
| biophysical and biochemical characterization of hepatitis a virus. | biophysical and biochemical analysis of hepatitis a virus has shown it to be a 27- to 32-nm icosahedral particle with 32 capsomers. the mature virion has a buoyant density of 1.33-1.34 g/cm3, a sedimentation coefficient of 156-160s, and is composed of four polypeptides with molecular weights of 30,000-33,000 (vp1), 24,000-27,000 (vp2), 21,000-23,000 (vp3), and 7,000-14,000 (vp4). the genome of hepatitis a virus consists of a single piece of single-stranded rna which sediments at 32-35s and has a ... | 1982 | 6292126 |
| [quantitative evaluation of the content of antibodies to hepatitis of a virus in serial immunoglobulin preparations]. | a total of 156 samples of several lots of immune serum globulin (isg) were tested for antibodies to hepatitis a virus (anti-hav). in this study the blocking variant of the solid-phase enzymoimmunological method was used. the samples under test were the production of 12 manufacturing enterprises in the ussr and i enterprise in czechoslovakia. all the samples under test were found to contain anti-hav within the limits from 2500-5000 to 20000-40000. the samples produced by different manufacturing e ... | 1982 | 6293225 |
| [current methods of detecting the hepatitis a virus and its antibodies]. | 1982 | 6295031 | |
| changing epidemiological characteristics of acute viral hepatitis in greece. | we have studied the epidemiological characteristics of acute viral hepatitis (avh) in adult patients admitted to the infectious diseases hospital of athens in 1980. commercially available radioimmunoassays were used for the detection of the hepatitis b surface antigen, its antibody, the antibody to the core of the hepatitis b virus (hbv) and the igg and igm antibody to the hepatitis a virus (hav). hbv was responsible for 59.9%, hav for 20.4% and hepatitis non-a, non-b virus for the remaining 19. ... | 1982 | 6802765 |
| acute b viral hepatitis becomes fulminant after infection with hepatitis a virus. | 1982 | 6805759 | |
| simultaneous acute infections with hepatitis non-a, non-b, and b viruses. | a case of overt acute hepatitis acquired through accidental needle stick was reported. the episode of hepatitis was classified as non-a, non-b because no hepatitis b marker or igm-anti-hav was detected during the peak of hepatitis. concurrent with non-a, non-b hepatitis, subclinical acute hepatitis b virus infection might have developed as evidence by de novo hepatitis b seroconversion 6 weeks later. it was concluded that hepatitis b and non-a, non-b viruses can be transmitted simultaneous by th ... | 1982 | 6807662 |
| hepatitis a and non-a, non-b viral hepatitis in são paulo, brazil: epidemiological, clinical and laboratory comparisons in hospitalized patients. | during a 33-month period, 295 patients with acute viral hepatitis were admitted to a state hospital for civil servants and their dependents in são paulo, brazil. seventy-nine per cent (232) were hbsag negative. to define the contribution of non-a, non-b viral hepatitis to hepatitis morbidity in this population, further serological studies were performed in 147 confirmed hbsag-negative patients. one hundred and twelve (76%) were serologically classified as hepatitis a based on identification of i ... | 1982 | 6807794 |
| acute non-a, non-b hepatitis in norway. clinical, epidemiological, and immunological characteristics in comparsion with hepatitis a. | serological analysis by radioimunoassay of sera from 297 patients hospitalized with acute non-toxic hepatitis was used for classification according to virus etiology. radioimmunoassays included tests for hepatitis b surface antigen (hbsag), antibody to hbsag (anti-hbs), antibody to hepatitis a virus (anti-hav), anti-hav of igm class, and antibody against cytomegalovirus (gmv) and epstein-barr virus. one patient with a significant rise in anti-cmv antibodies was classified as having cmv hepatitis ... | 1982 | 6817410 |
| fulminant type a viral hepatitis in a chimpanzee. | a case of a chimpanzee with fulminant hepatitis caused by spontaneous hepatitis a virus (hav) infection was reported. the liver at autopsy revealed massive liver cell necrosis with mononuclear and polymorphonuclear cell infiltration. aggregation of hav-like particles (22-25 nm in diameter) were found within the vesicles of hepatocytes under the electron microscope. immunofluorescent examination of the liver showed positive staining for hav antigen, c1q, c3, c4, immunoglobulin m (igm), and immuno ... | 1982 | 7041511 |
| [igm class antibodies against hepatitis a viruses in the differentiation of viral hepatitis]. | the sera of 64 patients with acute viral hepatitis which were previously hbsag negative by rpha were tested by ria methods for the presence of hbsag and anti-hbc, by eia method for hbc and anti-hbc and also by ria method for the presence of igm antibodies against hepatitis a virus. the pairs of sera were tested also for the presence of antibodies against cytomegalovirus and eb viruses. of the total of 64 patients, markers of fresh hb viral infection were proved in 5 patients, sera positive to ig ... | 1982 | 6765185 |
| prevalence of hepatitis a antibodies in a normal population and some selected groups of patients in norway. | the prevalence of hepatitis a virus antibodies was tested by radioimmunoassay in norway in healthy blood donors, in patients without clinical signs of liver diseases and in two selected groups of patients. the presence of hepatitis a antibodies was highly age-dependent in 625 normal persons. a major reduction occurred from 50 per cent or more in those born before 1938 to 10 per cent or less among those born after 1943. the decline of hepatitis a antibody prevalence was correlated to the history ... | 1982 | 7058777 |
| hepatitis a virus infection in households. | the behavior of hepatitis a virus (hav) infection among 980 members of 230 families in two rural districts of costa rica was studied prospectively from the recognition of the index case. the initial prevalence of detectable antibody (anti-hav) ranged from 26.2% in children to 71.4% in adults. the ratio of index to household-associated infections was significantly higher among children than among adolescents and adults, indicating that children were most often responsible for the hav introduction ... | 1982 | 7072704 |
| cryoglobulinemia in acute type-a hepatitis. | serum cryoglobulins were detected in 18 of 19 patients with type-a, and six of eight with type-b hepatitis. the predominant immunoglobulin in the cryoprecipitates was polyclonal igm. patients with type-a hepatitis had a significantly higher mean serum level of cryoglobulins when compared to those with type-b (106.9 vs. 20.5 micrograms/ml). igm anti-hepatitis-a virus activity was detected in all cryoprecipitates obtained from hepatitis-a patients. cryoglobulinemia in these patients was transient, ... | 1982 | 7083634 |
| hepatitis virus infection in flying airline personnel. | sera of 1126 flying personnel of an airline were tested for signs of ongoing or past infections with hepatitis b virus (hbv) or with hepatitis a virus (hav). the prevalence of anti-ha antibodies was similar in all professional categories of flying personnel and the same or slightly lower than in swiss blood donors. the frequency of immune markers identifying hbv immunity was similar in pilots, flight-engineers, and female flight attendants compared to swiss blood donors. however, hbv immunity wa ... | 1982 | 7115245 |
| hepatitis virus infection in an isolated canadian inuit (eskimo) population. | the epidemiology of hepatitis a virus (hav) and hepatitis b virus (hbv) infection was studied in a northern canadian inuit (eskimo) settlement. sera from 720 of the 850 inhabitants of baker lake, canada, were tested for markers of hav and hbv infection. anti-hav was present in 71% of the residents and its prevalence increased with age. serologic evidence of hbv infections was found in 27% of residents. the prevalence increased with age, being uncommon under the age of 20 (6%) and almost universa ... | 1982 | 7161596 |
| antibody to hepatitis b virus surface and core antigens in gambia pouched rats (cricetomys gambianus). | sera from 108 cricetomys gambianus (gambia pouched rat) were investigated for hbv and hav serum markers. 42.6% of them evidenced anti-hbs and 12.0% anti-hbc. hbs ag was never detected. the most probable hypothesis is that these animals were infected with a new virus related to hbv. | 1982 | 7184516 |
| an epidemic outbreak of hepatitis a among homosexual men in stockholm. hepatitis a, a special hazard for the male homosexual subpopulation in sweden. | in 1979-1980, a distinct outbreak of hepatitis a occurred among homosexual men in stockholm, sweden, city and county area. the epidemic comprised 145 known cases. it began in december 1979 and progressed in waves during the following 10 months, with three distinct peaks separated by about six-week intervals. actually, the incidence of hepatitis a in the stockholm area showed a fivefold increase during 1980 as compared to the previous year. clinical serologic, and social characteristics were stud ... | 1982 | 7137147 |
| radioimmunoassay detection of igm antibodies to the hepatitis b core antigen in hbsag liver disease. | a radioimmunoassay is described for detection of igm antibody to the hepatitis b core antigen. the assay is based on the selective absorption of igm immunoglobulins from test serum by anti-igm fixed on a solid phase, followed by incubation with hbcag and radiolabeled anti-hbc of igg type. igm anti-hbc was found in high titers in all the patients with acute hepatitis b; in two of four patients whose acute hepatitis progressed to chronicity, igm anti- hbc disappeared in 4-6 months despite continui ... | 1982 | 6985422 |
| prevalence of antibody to hepatitis a in iceland in relation to age, sex, and number of notified cases of hepatitis. | the prevalence of antibody to hepatitis a virus (anti-hav) was investigated in 623 outpatients in iceland. no difference in anti-hav prevalence according to sex or rural vs. urban residence was found. the prevalence rates in different age groups were found to be comparable to those in the scandinavian countries, increasing from 1.6% (1/63) in persons below 20 years of age to 66% (51/77) in persons above 60 years of age. the numbers of notified cases of hepatitis (epidemic jaundice) in iceland du ... | 1982 | 7124712 |
| hepatitis b and a virus antibodies in alcoholic steatosis and cirrhosis. | sera from 74 alcoholics with cirrhosis and 63 alcoholics with steatosis were tested for antibody to hepatitis b surface antigen, to hepatitis b core antigen, and to hepatitis a virus by radioimmunoassay or enzyme-linked immunosorbent assay. no significant difference between the two groups of alcoholics could be found concerning the prevalence of these antibodies. the total group of patients had antibody to hepatitis b surface antigen or hepatitis b core antigen, or both, significantly (p less th ... | 1982 | 6284803 |
| viral hepatitis. | three forms of viral hepatitis can be recognized: hepatitis a, hepatitis b, and hepatitis non-a, non-b. hepatitis a is caused by a picornavirus, is transmitted by the faceal-oral route, does not become chronic, and no chronic virus carriers exist. the virus can be grown in cell cultures, and killed as well as live attenuated virus vaccines are under development. hepatitis b is caused by an enveloped virus containing a circular, double-stranded form of dna. the disease is transmitted parenterally ... | 1982 | 6817933 |
| prevalence of antibody to hepatitis a virus in a canadian inuit community. | to determine the prevalence of hepatitis a in a canadian inuit population, serum from 85% of the 850 inhabitants of baker lake, northwest territories, was tested by radioimmunoassay for antibody to the hepatitis a virus (anti-hav). the overall prevalence of anti-hav in the community was 71%. exposure to the virus occurred early in life, such that by the age of 6 years 53% of the children had anti-hav in their serum. the rate approached 100% by the age of 50 years. these findings document the ubi ... | 1982 | 7139503 |
| serodiagnosis of acute hepatitis b virus infection by a modified competitive binding radioimmunoassay. | using the staphylococcus aureus absorption method, we have modified a commercial radioimmunoassay kit for the determination of total antibody to hepatitis b core antigen so that we can now determine the predominant globulin species of that antibody. one-hundred percent of acute hepatitis b sera had a predominance of immunoglobulin m antibody to hepatitis b core antigen, whereas immunoglobulin g antibody to hepatitis b core antigen was predominant in 98.2% of chronic hepatitis b surface antigen c ... | 1982 | 7153350 |
| acute type b hepatitis among hbsag negative patients detected by anti-hbc igm. | a consecutive group of 169 patients with acute hepatitis found negative for hepatitis b surface antigen (hbsag) and negative for igm antibody against hepatitis a (anti-hav igm) was studied for presence of igm antibody against hepatitis b core antigen (anti-hbc igm) by elisa. anti-hbc igm was found in a total of 34 of 60 patients with detectable total anti-hbc. one hundred and nine patients had no detectable anti-hbc igm and no total anti-hbc and were thus considered as having acute non-a, non-b ... | 1982 | 6976301 |
| a longitudinal study of hepatitis infection in an institution for the mentally retarded. | the natural history of hepatitis a and b infections in a large institution for the mentally retarded were studied over an eight year period. serum samples were obtained from most subjects on three occasions and tested for anti-hav, hbsag, anti-hbs and occasionally anti-hbc, by solid-phase radioimmunoassay. hepatitis a was found to have been a common infection was 74.8% of subjects having detectable levels of antibody. the virus does not appear to be endemic, as the prevalence of antibody in chil ... | 1982 | 6952837 |
| clinical characteristics and response to therapy in egyptian children heavily infected with schistosoma mansoni. | forty-one egyptian schoolchildren (36 boys and five girls; age, 12-16 years) who were heavily infected with schistosoma mansoni were studied. symptomatic subjects had swimmer's itch and hematochezia. hepatomegaly was found in 39 and splenomegaly in 31 children. all subjects had eosinophilia, 13 had anemia, 31 had elevated levels of serum globulins, and nine had elevated levels of alkaline phosphatase. all but one subject had antibody to hepatitis a virus, and 26 had antibody to hepatitis b core ... | 1982 | 7086203 |
| [role of the water factor in the transmission of the hepatitis a virus]. | 1982 | 7101795 | |
| guillain-barré syndrome associated with hepatitis a in a male homosexual. | 1982 | 7104658 | |
| antibody to hepatitis a virus in young inmates. | 1982 | 7108284 | |
| nosocomial hepatitis a transmission by an adult patient with diarrhea. | hepatitis a occurred in five registered nurses, a licensed practical nurse, and a recently discharged patient at a community hospital; one of these seven was asymptomatic. all had been exposed to a woman with confirmed hepatitis a who had undergone elective cholecystectomy and who had had vomiting, diarrhea, and fecal incontinence during the eight days before onset of jaundice. of the 107 hospital workers identified as having at least some exposure to the source patient, 58 (54.2 percent) had no ... | 1982 | 7114079 |
| [results from the hepatitis a-virus diagnostic of the hygiene-institut in tübingen]. | the age-specific and seasonal distribution of serologically confirmed hepatitis a-cases in the area of tübingen in southern germany is reported. during 1978-1980 most of the hepatitis a-cases diagnosed by high anti-hav-igm titers occurred from september to december. the age distribution of patients with german names showed two age-related peaks, the first one in young children 5-10 years of age and a second one in young adults between 20-30 years. in patients with names suggesting mediterranean ... | 1982 | 7124159 |
| virus antibodies in the serum of patients with liver disease. | two hundred and twenty-six patients suspected of having liver disease were examined clinically, by a liver biopsy and laboratory test, according to a prospective scheme. blood samples obtained just before the liver biopsy were coded and subsequently examined blindly, using the complement fixation test (cft). the antigens were influenza a and b viruses, parainfluenza 1, 2, and 3, respiratory syncytial viruses, varicella, morbilli, cytomegalo and herpes simplex viruses. the sera were also examined ... | 1982 | 7134837 |
| experimental infection of the new world owl monkey (aotus trivirgatus) with hepatitis a virus. | epidemiological studies have demonstrated the susceptibility of the owl monkey (aotus trivirgatus) to hepatitis a virus, but have not shown an association between infection and histopathological or chemical evidence of liver disease. therefore, 12 seronegative, colony-bred monkeys were inoculated intravenously with a fecal suspension containing either pa33 strain hepatitis a virus (a strain recovered from a naturally infected aotus sp.) or hm-175 virus (recovered from a human). viral antigen was ... | 1983 | 6840861 |
| incidence of hepatitis a virus infection among japanese volunteers staying in developing countries. | incidence of hepatitis a virus infection was studied serologically in 260 adult males and females sent for volunteer service to developing countries from japan. among 225 initially seronegative subjects, 29 (12.9%) were seropositive to hepatitis a virus at their return from two year's overseas service. seroconversion occurred in none of 39 subjects who received two doses or more of prophylactic administration of human immunoglobulin. there were clinical records of acute non-b hepatitis in 10 sub ... | 1983 | 6663803 |
| hepatitis a virus infection. summary of discussion and statement of opinions on selected issues at an international workshop. | 1983 | 6840058 | |
| the risk of hepatitis a virus infection for hospital staff. | the prevalence of antiha was assessed in 594 hospital employees and in control groups comprising 932 "healthy" adults not working in the hospital, selected from different socioeconomic classes. age specific antiha prevalence which was lower in doctors than in nurses and ancillary staff, was also found to be lower in each group than in the respective controls, matched according to socioeconomic criteria. it is concluded that in our population (i.e. high risk area) the hospital environment does no ... | 1983 | 6661287 |
| increased occurrence of hepatitis a with cyclic outbreaks among drug addicts in a swedish community. | to determine the prevalence of antibodies to hepatitis a virus (anti-hav) among drug addicts, sera collected in a swedish city during a ten-year period from 234 drug addicts with acute hepatitis b were tested for anti-hav. the results were compared with the normal population, where only 3.8% of those born after 1950 were anti-hav-positive. in individuals born between 1941 and 1965, 8.2% in the normal population and 30.2% of the drug addicts were anti-hav-positive (p less than 0.001). the level o ... | 1983 | 6618674 |
| haemolytic-uraemic syndrome associated with hepatitis a virus infection. | 1983 | 6618848 | |
| are nuclear particles specific for non-a, non-b hepatitis? | this study reports the findings of an electron microscopic search for so-called non-a, non-b nuclear particles in liver biopsies from patients with mainly chronic or prolonged liver disease and from chimpanzees. in patients without hepatitis b virus or acute hepatitis a virus serological markers, non-a, non-b-like nuclear particles were seen in hepatocytes in 28 of 31 cases of presumed non-a, non-b hepatitis, but also in 11 of 12 cases of liver disease not usually attributed to hepatitis viruses ... | 1983 | 6407955 |
| guillain-barré syndrome associated with acute hepatitis a. | a case of guillain-barré syndrome in a 49-year-old male is described. the syndrome presented as tetraplegia with sensory impairment and the pre-icteric phase of acute hepatitis a. both viral hepatitis and neurologic disturbances improved, although neurologic changes lasted for 3 months after the onset. ha igm antibody in cerebrospinal fluid was first manifest with onset of neurologic symptoms. on the basis of this finding and some reports in the literature it seems possible that the guillain-bar ... | 1983 | 6608463 |
| hepatitis a in swedish foreign travellers. | scandinavians present antibodies to hepatitis a virus (anti-hav) in low frequency or under 25% in ages up to 50 years. this means that scandinavians ought to be particularly vulnerable when travelling to hyperendemic hepatitis a areas. about one million swedes travel to the mediterranean area each year and about 75% of these travellers receive gammaglobulin before departure. since hepatitis a is a notifiable disease in sweden it is possible to compare the incidence of this disease in travellers ... | 1983 | 6653896 |
| prognostic significance of piecemeal necrosis in acute viral hepatitis. | the predictive value of piecemeal necrosis (pmn) in acute hepatitis was investigated in 62 patients (39 hepatitis b virus infection, 9 hepatitis a virus infection and 14 possible hepatitis nanb virus infection). the 62 initial biopsies were blindly recoded and classified into three groups: 1. acute hepatitis with signs of possible transition to chronicity (ahtc) (n = 35) (i.e. a picture of acute hepatitis associated with pmn). 2. ahtc-borderline group (bl) (n = 15) (i.e. a picture of acute hepat ... | 1983 | 6406783 |
| viral hepatitis among parenteral drug addicts attending a danish addiction clinic. | 100 parenteral drug abusers attending an addiction clinic were studied for past or present infection with hepatitis a and b virus (hav and hbv) by sensitive serological assays for hepatitis b surface and e-antigen and antibodies to hbsag, hbeag, hbcag and hav. 44% of the individuals had past hav infection, which is 4 times as high compared to the general population in denmark. 83% had evidence of past or present hbv infection with no difference between men and women. this is 30 times higher than ... | 1983 | 6603653 |
| hyperendemicity of viral hepatitis in the neapolitan area: an epidemiological study. | an epidemiological study was performed in order to evaluate the diffusion pattern and risk factors in an area of hyperendemicity of viral hepatitis in the neapolitan hinterland. eight hundred-fifty seven asymptomatic subjects, aged 10 to 65 years, who consecutively went to the public health office of the city of afragola to ask for a health certificate, were studied. they were interviewed with an epidemiological questionnaire and tested for a basic liver profile and serological markers of both h ... | 1983 | 6626321 |
| hepatitis a and hepatitis b virus infection in children and adolescents in north-east italy. | the sera of 722 children and adolescents without overt liver disease were tested for hepatitis b surface antigen (hbsag), antihbs and anti-hepatitis b core anti-hbc; 658 of the sera were also tested for anti-hepatitis a virus anti-hav. except for the "passive" antibody peak observed in babies, the anti-hav age-specific prevalence was negligible until the age of 3; it then increased, reaching 35% by the age of 15. serological evidence of hbv was present in 16% of the subjects: this prevalence was ... | 1983 | 6631426 |
| hepatitis a infection in chronic carriers of hepatitis b virus. | by routine screening for serologic markers of hepatitis a and b in patients with acute hepatitis, 30 chronic carriers of hepatitis b virus with serologic evidence of acute hepatitis a and two patients with simultaneous acute infection with hepatitis a virus and hepatitis b virus were detected. for evaluation of clinical data, two major risk groups were distinguished. nine patients were drug addicts and 17 were children and young adults from mediterranean countries or southeast asia. during the a ... | 1983 | 6862364 |
| aspects of the ecology of viral hepatitis. | human viral hepatitis, a major public health problem throughout the world, is caused by several different viruses. hepatitis a virus is a member of the enterovirus genus. hepatitis b is as yet an unclassified dna virus. a number of unidentified viruses cause at least two different types of non-a, non-b hepatitis. the delta agent, which has been described more recently, is a transmissible agent which is dependent for its replication on a helper function provided by hepatitis b virus. aspects of t ... | 1983 | 6432521 |
| aplastic anemia and non-a, non-b hepatitis. | severe aplastic anemia is a rare but important complication of hepatitis. the agent(s) responsible for the hepatitis in these cases have not been well defined. sixteen patient with hepatitis-associated aplastic anemia were studied for evidence of recent infection with hepatitis a virus, hepatitis b virus, cytomegalovirus, epstein-barr virus, and toxoplasma. results were compared with data from 10 randomly selected patients with aplastic anemia unassociated with hepatitis. of the 16 patients, rec ... | 1983 | 6295145 |
| prevalence of antibody to hepatitis a virus in okinawa and kyushu, japan. | between 1968 and 1981, a total of 1955 serum samples from healthy subjects chosen at random in seven districts of okinawa and two districts of kyushu were surveyed for antibody to hepatitis a virus (anti-hav) by radioimmunoassay. overall prevalence of anti-hav was 55.1% in okinawa and 35.9% in kyushu. prevalence of less than 10% was observed in subjects less than or equal to 14 years of age in okinawa and less than or equal to 24 years of age in kyushu. in three of the districts of okinawa, seco ... | 1983 | 6297296 |
| effect of chlorine treatment on infectivity of hepatitis a virus. | this study examined the effect of chlorine treatment on the infectivity of hepatitis a virus (hav). prodromal chimpanzee feces, shown to induce hepatitis in marmosets (saguinus sp.), was clarified, and the virus was precipitated with 7% polyethylene glycol 6000, harvested, and resuspended. the suspension was layered onto 5 to 30% linear sucrose gradients and centrifuged; the fractions containing hav were dialyzed, and a 1:500,000 dilution of this preparation induced hepatitis and seroconversion ... | 1983 | 6297391 |
| the frequency of hepatitis a and b viruses as the offending viral type in suspected hepatitis. | three hundred and thirty blood samples from patients suspected of having hepatitis on clinical grounds but in whom the aetiology of the hepatitis was unknown (93 whites and 237 blacks) were tested for the presence of hepatitis b surface antigen (hbsag), anti-hbs, total anti-hepatitis a virus (hav) activity and anti-hav of the igm class. these tests identified the offending hepatitis virus whenever this was type a or type b, and also revealed the patient's immune status in respect of these viruse ... | 1983 | 6294888 |
| an evaluation of immune electron microscopy as a method for the quantitation of virus particles. | a comparison is made between poliovirus titres obtained by immune electron microscopy and those obtained by plaque assay. the former method yields smaller values which cannot be explained by inefficient sedimentation of virus-antibody clumps or incomplete settling on the grid. using this comparison and immune electron microscopy the theoretical titre of hepatitis a virus can be estimated. | 1983 | 6300158 |
| studies in chimpanzees of live, attenuated hepatitis a vaccine candidates. | human hepatitis a virus was attenuated in virulence for chimpanzees by passage in frhk6 and human diploid lung fibroblast cell cultures. a number of variants were developed by passage in cell cultures which showed different levels of virulence/attenuation for chimpanzees. these results were compared to those obtained with marmosets and reported previously. in general, most variants behaved similarly in the two animal types. two chimpanzees which gave vaccine-like responses following inoculation ... | 1983 | 6302710 |
| value of screening for markers of hepatitis in dialysis units. | the value of monitoring the serum activity of sgot, as well as markers of hepatitis b virus and hepatitis a virus infections, in the patients and staff of two dialysis units has been assessed retrospectively. sera were checked each month for sgot and hbsag on 406 patients and 170 staff members over a 4-year period. anti-hbc, anti-hbs, and anti-hepatitis a antibodies were assayed on the stored sera. only 30% of the patients had normal sgot values (less than 65 units per ml) on all occasions. most ... | 1983 | 6305817 |
| radioimmunofocus assay for quantitation of hepatitis a virus in cell cultures. | a new method is described for the quantitation of hepatitis a virus in cell cultures, based on the immune autoradiographic detection of foci of infected cells (radioimmunofoci) developing beneath an agarose overlay 14 days after the inoculation of petri dish cultures of continuous african green monkey kidney cells (bs-c-1). the number of foci developing in each culture was linearly related to the dose of hepatitis a virus (either hm-175 or pa-21 strain) inoculated. focus development was prevente ... | 1983 | 6306048 |
| age-specific prevalence of antibody to rotavirus, escherichia coli heat-labile enterotoxin, norwalk virus, and hepatitis a virus in a rural community in thailand. | a serological survey in rural thailand demonstrated that inhabitants acquired antibody to rotavirus between the ages of 6 months and 6 years, to norwalk virus between the ages of 4 and 5 years, and to hepatitis a between the ages of 6 and 35 years. antibody of escherichia coli heat-labile toxin was most prevalent between 1 and 4 years and 18 and 25 years of age. | 1983 | 6306049 |
| detection and persistence of specific iga antibodies in serum of patients with hepatitis a by capture radioimmunoassay. | the serum immunoglobulin a (iga) response to hepatitis a virus (hav) was investigated with a sensitive capture radioimmunoassay. in serial serum samples drawn from 15 patients with viral hepatitis a, iga anti-hav antibodies reached their highest titer between 1-2 weeks after onset and peak titers ranged from 10,000-20,000. serum samples were available from six patients 30-32 months after onset of illness. these samples were all positive for iga anti-hav and some had titers similar to peak titers ... | 1983 | 6308139 |
| [the hepatitis a virus antibody (anti-hav) in chronic diffuse liver diseases]. | 1983 | 6308536 | |
| national case-control study of kaposi's sarcoma and pneumocystis carinii pneumonia in homosexual men: part 2. laboratory results. | the centers for disease control conducted a case-control study to investigate an outbreak of kaposi's sarcoma and pneumocystis carinii pneumonia in homosexual men. the occurrence of these diseases was found to be associated with certain aspects of lifestyle, including a greater number of male sex partners per year, exposure to feces during sex, history of syphilis and non-b hepatitis, treatment for enteric parasites, and use of various illicit substances. laboratory studies reflected both this l ... | 1983 | 6309049 |
| topology and immunoreactivity of capsid proteins in hepatitis a virus. | hepatitis a virus (hav) was propagated in a hepatoma cell line and complete viral particles with a density of 1.34 g/ml were purified from cell extracts. the topography of the viral proteins (vps) was studied by surface labelling with 125i and a solid-phase oxidant. the order of labelling intensity in complete particles was vp1 much greater than vp3 greater than vp2; labelling of vp4 was undetectable. when the particles were denatured with sodium dodecyl sulfate at 100 degrees c before iodinatio ... | 1983 | 6310355 |
| molecular cloning and characterization of hepatitis a virus cdna. | double-stranded cdna was synthesized from hepatitis a virus (hav) rna and inserted into the pst i site of pbr322. restriction endonuclease digestion and cross-hybridization of fragments yielded a map of overlapping cloned cdnas that included at least 99% of the viral genome. molecular clones containing hav cdna were identified by hybridizing cloned cdna to electrophoretically resolved rna from uninfected and hav-infected tissue culture cells. cloned cdna probes specifically hybridized to rna fro ... | 1983 | 6310601 |
| inactivation of hepatitis a virus added to pooled human plasma by beta-propiolactone treatment and ultraviolet irradiation. | 1983 | 6313360 | |
| incidence of hepatitis a virus infection in children in taipei, taiwan. | to understand the prevalence and incidence of hepatitis a virus (hav) infection in chinese children in taiwan, we determined the age-specific prevalence of hepatitis a antibodies (anti-hav) in 823 children, ranging from birth (cord blood) to 19 years of age. the frequency of anti-hav rose with increasing age with three different slopes, probably reflecting different age-specific incidences: lowest under 4 years of age, intermediate between 4 and 10 years, and highest above 10 years. we obtained ... | 1983 | 6313545 |
| posttransfusion hepatitis type a. | hepatitis a virus (hav) transmission through blood is a rare but potential cause of posttransfusion hepatitis. we can now document such a case supported by laboratory evidence of hav in the donor blood. a 10-year-old girl manifested icteric hepatitis a 31 days after receiving a single unit of packed rbcs from a donor who subsequently experienced hepatitis a and died in hepatic failure. hepatitis a virus antigen was detected in the donor's hepatocytes and in plasma obtained from the original dono ... | 1983 | 6313973 |
| [serum study of monkeys and other types of animals for antibodies to hepatitis a virus]. | 1983 | 6314667 | |
| [combination of radioimmunological and immunoelectron microscopic methods for detecting hepatitis a virus]. | the possibility of combined performance of radioimmunoassay (ria) and immune electron microscopy (iem) in one preparation using protein a of staphylococcus aureus for hepatitis a virus (hav) detection in fecal specimens from hepatitis a patients within a short time (40-50 min) has been demonstrated. in the examinations of one preparation by ria and iem, their sensitivity was found to be approximately similar. according to ria, a high content of hav antigen was observed in those preparations wher ... | 1983 | 6314673 |