Publications

dietary pectic oligosaccharide administration improves growth performance and immunity in weaned pigs infected by rotavirus.	rotavirus infection is one of the main pathogenic causes of gastroenteritis and diarrhea in children and young animals. the present study aimed to determine whether dietary pectic oligosaccharide (pos) supplementation could improve the growth performance and immunity in weaned pigs infected by porcine rotavirus (prv). twenty-eight crossbred weaned galts were randomly divided into two groups fed basal diet with or without pos for 18 days. on the 15th day, prv was orally infused to half of the pig ...	2017	28320203
analysis of porcine rotavirus a enterotoxin gene for structure-function relationship.	rotavirus (rv) infected piglets are presumed to be the latent sources of heterologous rv infection to humans and other animals. in rvs, non-structural protein 4 (nsp4) is the major virulence factor with pleiotropic properties. in this study, we analyzed nsp4 gene from porcine rvs, isolated from diarrheic and non-diarrheic cases, at different levels of protein folding to explore any correlation with their diarrhea inducing capabilities and evolution of nsp4 in porcine population. the full length ...	2017	28057906
whole genome analysis provides evidence for porcine-to-simian interspecies transmission of rotavirus-a.	we report here whole genome analysis of a porcine rotavirus-a (rva) strain rva/pig-wt/kna/et8b/2015/g5p[13] detected in a diarrheic piglet, and nearly whole genome (except for vp4 gene) analysis of a simian rva strain rva/simian-wt/kna/08979/2015/g5p[x] detected in a non-diarrheic african green monkey (agm) on the island of st. kitts, caribbean region. strain et8b exhibited a g5-p[13]-i5-r1-c1-m1-a8-n1-t7-e1-h1 genotype constellation that was identical to those of brazilian porcine rva g5p[13] s ...	2017	28039076
genomic organization and recombination analysis of a porcine sapovirus identified from a piglet with diarrhea in china.	sapovirus (sav), a member of the family caliciviridae, is an etiologic agent of gastroenteritis in humans and pigs. to date, both intra- and inter-genogroup recombinant strains have been reported in many countries except for china. here, we report an intra-genogroup recombination of porcine sav identified from a piglet with diarrhea of china.	2017	28302145
il-22 suppresses the infection of porcine enteric coronaviruses and rotavirus by activating stat3 signal pathway.	interleukin-22 (il-22), a member of the il-10 superfamily, plays essential roles in fighting against mucosal microbial infection and maintaining mucosal barrier integrity within the intestine. however, little knowledge exists on the ability of porcine il-22 (pil-22) to fight against viral infection in the gut. in this study, we found that recombinant mature pil-22 (mpil-22) inhibited the infection of multiple diarrhea viruses, including alpha coronavirus, porcine epidemic diarrhea virus (pedv), ...	2017	28322925