Publications

gynecologic infections in the pediatric age group.		1984	6610860
fatty acid, polar lipid and wall amino acid composition of gardnerella vaginalis.	representative strains of gardnerella vaginalis were degraded using both an alkaline and an acid methanolysis and the fatty acid methyl esters released examined by thin-layer and gas chromatography. the profiles obtained were both qualitatively and quantitatively similar and were comprised of straight chain saturated and unsaturated non-hydroxylated fatty acids with hexadecanoic acid (16:0) and octadecenoic acid (18:1) the major components. all of the strains contained very characteristic polar ...	1984	6611140
a study of the susceptibility of three species of primate to vaginal colonization with gardnerella vaginalis.	in an attempt to develop an animal model of gardnerella-associated vaginitis, several strains of gardnerella vaginalis were inoculated into the lower genital tract of female pig-tailed macaques, tamarins and chimpanzees. g. vaginalis was not recovered from either tamarins or chimpanzees, but was recovered from each of 1o pig-tailed macaques inoculated with either of two freshly isolated gardnerella strains, colonization persisting for 11-39 days. examination of gram-stained vaginal smears obtain ...	1984	6611168
isolation of gardnerella vaginalis from women attending gynaecological clinics and general practice surgeries.		1984	6611356
[first experience with the diagnosis of gardnerella vaginalis].		1984	6230162
in vitro activity of ciprofloxacin and norfloxacin against gardnerella vaginalis.		1984	6237906
non-gonococcal urethritis in men & its response to therapy.		1984	6097537
[microbiologic findings in vaginal discharges].	microbiological examinations were performed in 247 women complaining of vaginal discharge. an average of 3.9 different organisms was isolated from each patient. gardnerella vaginalis was found in 62.8% of all women. candida spp. were seen in 22.7%. trichomonas vaginalis occurred in 6.5%, neisseria gonorrhoeae in 1.2%, chlamydia trachomatis in 10.1%, mycoplasmata in 13.8%, cytomegalovirus in 2.8%, and herpes simplex type 2-virus in 1.1%. none of the above was found in 17.4% of the patients. stati ...	1984	6098512
upper urinary tract infection with gardnerella vaginalis in a woman.		1984	6332020
microbiology of vaginitis associated with the intrauterine contraceptive device.	a malodorous, homogeneous, grey, thin and non-purulent discharge, which resembles non-specific vaginitis occurs in 20% of women with an intrauterine contraceptive device (iucd); four times more common than in non-users. the aim of this investigation was to study the bacteriological aetiology of this iucd-associated vaginal discharge, and to assess whether the infection was ascendent. no specific microbiological aetiology was found, but the normal, lactobacillus-dominated microbial vaginal flora ...	1984	6332643
biotypes of gardnerella vaginalis.	a simple and reproducible scheme for identifying biotypes of gardnerella vaginalis has been developed, based on reactions for lipase, hippurate hydrolysis, and beta-galactosidase. among a total of 359 strains tested, eight biotypes were observed, the most common ones being types 1 (beta-galactosidase positive, lipase positive, hippurate positive), 2 (beta-galactosidase negative, lipase positive, hippurate positive), and 5 (beta-galactosidase negative, lipase negative, hippurate positive). the di ...	1984	6333436
treatment of gardnerella vaginalis vaginitis.		1984	6333920
anaerobic vaginosis: therapeutic and epidemiological aspects.		1984	6334683
use of betadine in the pregnant woman.		1984	6334771
susceptibility of gardnerella vaginalis to thiamphenicol: clinical experience with nonspecific vaginitis.	we compared the in-vitro activity of thiamphenicol against 100 strains of gardnerella vaginalis with the activity of 11 other antimicrobial agents. the mics for thiamphenicol ranged from 0.39 micrograms/ml to 6.25 micrograms/ml. the concentration at which 50% of strains were inhibited (mic50) was 1.96 micrograms/ml, and the concentration at which 90% of strains were inhibited (mic90) was 3.93 micrograms/ml. all strains were very susceptible to erythromycin, chloramphenicol, beta-lactam antibioti ...	1984	6335301
a newly discovered sialidase from gardnerella vaginalis.	a sialidase (neuraminidase, acylneuraminosyl hydrolase, ec 3.2.1.18) has been discovered and isolated from gardnerella vaginalis (ex. haemophilus vaginalis), a possibly pathogenic inhabitant of the female genital tract. bacteria were grown in peptone-yeast-extract medium with 2.0 mm n-acetylmannosamine as enzyme inductor under co2 atmosphere. sialidase activity was found in the bacterial sediment and in the culture medium. the enzyme was liberated from the cells by ultrasonic treatment. purifica ...	1984	6335332
experimental infection of mares with haemophilus equigenitalis.	inoculation of haemophilus equigenitalis into the uterus of 7 mares caused a disease clinically indistinguishable from contagious equine metritis. the duration of clinical signs varied from 4 to 11 days. the causative organism persisted for a relatively short time (2 to 10 weeks) in 5 mares, but in 2 others it established a carrier status and persisted until they were killed 6 and 10 months after infection. h. equigenitalis was recovered from the vestibule of the vagina and from a combined swab ...	1984	6335966
clinical aspects of gardnerella vaginalis-associated vaginitis. a review of the literature.	almost 30 years ago gardner & dukes introduced the term haemophilus vaginalis vaginitis. most authors agree that this disease entity is characterized by a malodorous, homogeneous, greyish-white discharge, displaying clue cells in the wet-mount preparation. the diagnosis can be made in the office, the microscope being the most important diagnostic tool. there still seems to be some controversy regarding cause and clinical manifestations of the condition. a lack of uniformity in case definition an ...	1984	6336130
vaginal colonization with gardnerella vaginalis and anaerobic curved rods.	ninety-four women colonized with anaerobic curved rods (cr) and/or gardnerella vaginalis, were studied. of these women, 34 were culture-positive for the long variant of cr. eight of these latter women also harboured the short variant of these bacteria. in women colonized with cr, none had a predominance of lactobacilli in their vaginal flora, which was the case in 26 of the 60 women not harbouring cr. g. vaginalis was isolated from all 94 women. mycoplasma hominis occurred significantly more oft ...	1984	6336131
studies on the mechanism of adhesion of gardnerella vaginalis to human erythrocytes.	a quantitative method using radiolabelled bacteria was used to examine the adherence of gardnerella vaginalis to human erythrocytes. adherence was mannose resistant, but inhibited by d-galactose and d-galactosamine. it was independent of temperature, but reduced at ph 3. there was considerable variation in the adherence of different isolates of g. vaginalis to human erythrocytes.	1984	6336132
can gardnerella vaginalis and anaerobic curved rods attach to vaginal epithelial cells in vitro, resulting in clue cells?	vaginal epithelial cells were taken from asymptomatic patients and from patients with non-specific vaginosis. four bacterial species-gardnerella vaginalis, wolinella succinogenes and short and long anaerobic curved rods-were tested in vitro regarding attachment to the epithelial cells. in most experiments the curved rods and w. succinogenes attached to the cells. less often, incubation with g. vaginalis resulted in cell attachment. there was no difference in attachment ability between the short ...	1984	6336133
the grivet monkey as a model for study of vaginitis. challenge with anaerobic curved rods and gardnerella vaginalis.	the grivet monkey was used as an experimental model for vaginitis. gardnerella vaginalis was used for challenge in one monkey. g. vaginalis plus a long variant (lcr) of a hitherto unclassified anaerobic curved rod (cr) in another 2 monkeys, this lcr alone in 2, a short variant (scr) of cr in 2, and g. vaginalis plus scr in one monkey. all the bacterial strains had been isolated from human vaginal specimens. in the 2 monkeys exposed to g. vaginalis plus lcr, distinct signs of bacterial vaginosis ...	1984	6336134
vaginal colonization of pig-tailed macaques by gardnerella vaginalis.	ten pig-tailed macaques inoculated intravaginally with gardnerella vaginalis organisms were colonized for 11-39 days. in contrast, 4 tamarins and 3 chimpanzees inoculated similarly failed to become colonized. examination of gram-stained vaginal smears obtained from infected pig-tailed macaques failed to demonstrate clue cells, a feature which is pathognomonic of non-specific vaginitis in humans. additionally, the ph value, the levels of non-volatile fatty acids and the anaerobic flora of the mac ...	1984	6336135
bacterial vaginosis during pregnancy. an association with prematurity and postpartum complications.	although bacterial vaginosis (bv) is a common disorder associated with high concentrations of potentially pathogenic micro-organisms, bv has not yet been linked to infections outside the vagina. to investigate the association of bv with adverse outcomes during or following pregnancy, we analysed the prevalence of bv among women with and without premature labor, and early-onset postpartum endometritis. bacterial vaginosis was identified by gas-liquid chromatographic criteria in 28 (49%) of 57 wom ...	1984	6336136
bacterial vaginosis. an evaluation of treatment.	various treatment regimens for bacterial vaginosis are reviewed. orally administered metronidazole and tinidazole have been consistently successful, whereas widely variable results have been published from use of peroral ampicillin or tetracycline and from locally applied sulphonamide cream. the rationale for different treatments is discussed, with particular regard to the pathogenesis of the disease.	1984	6336137
gynatren/solcotrichovac in the treatment of non-specific vaginitides.		1984	6336151
treatment of non-specific colpitis with gynatren/solcotrichovac.		1984	6336152
[bacterial vaginitis. microbiology, diagnosis, therapy and complications].		1985	3871690
vaginal infection with gardnerella vaginalis.		1985	3871942
vaginitis due to gardnerella vaginalis and to candida albicans in sexual abuse.	sexually transmitted diseases may be transferred to children and adolescents during voluntary or involuntary sexual contact. two children are reported with the unusual association of sexual abuse and candida albicans or gardnerella vaginalis infections. awareness of the techniques for diagnosis of these infections is essential for appropriate management of the abused child. these organisms should not be considered normal flora when found in symptomatic children and adolescents and should raise t ...	1985	3872154
treatment of gardnerella vaginalis vaginitis.		1985	3872155
anaerobes and gardnerella vaginalis in non-specific vaginitis.	clinical evidence of bacterial vaginosis was present in 25 (35%) of 72 patients attending a london venereology clinic and correlated significantly with abnormal organic acids in vaginal secretions (24/25), with gardnerella vaginalis on culture (17/25), with complaints of vaginal malodour (15/25), and with a relative scarcity of white blood cells in vaginal secretions. anaerobic vaginal flora were presumptively identified by gas-liquid chromatographic analysis of organic acids found in vaginal se ...	1985	3872256
carriage of gardnerella vaginalis and anaerobes in semen.	gardnerella vaginalis was isolated from 22 (38%) of 58 semen samples obtained from men attending an infertility clinic. counts ranged from 1.2 x 10(3) to greater than 10(7) colony forming units (cfu)/ml. there was no association between the isolation of g vaginalis and the sperm count. twenty (34.4%) samples contained non-sporing anaerobes and nine (15.5%) both anaerobes and g vaginalis. the infective dose of g vaginalis is not known, but semen could act as a medium for its sexual transmission.	1985	3872257
single-dose metronidazole for gardnerella vaginalis.		1985	3872426
hemophilus influenzae in urine.		1985	3872646
[gardnerella vaginitis].		1985	3873117
colistin-oxolinic acid blood agar: a selective medium for the isolation of gardnerella vaginalis.	colistin-oxolinic acid medium is proposed as a selective isolation medium for gardnerella vaginalis. the medium is effective in inhibiting staphylococci and gram-negative bacteria while allowing growth of g. vaginalis.	1985	3873471
vaginitis.	vaginitis is one of the most common complaints of women in the united states today. about 90% of patients with this problem suffer from infection of the vagina caused by candida, gardnerella, or trichomonas. the diagnosis and effective treatment of these common infections depend on accurate identification of the entity, effective specific therapy, and restoration of the normal ecosystem of the vagina. at the same time women should be made aware that not all discharge means infection and that any ...	1985	3873872
identification of gardnerella vaginalis with the api 20 strep system.	a total of 137 strains of gardnerella vaginalis were examined by the api 20 strep system. the system was shown to be reliable when the tests were compared with standard identification methods, and very little confusion occurred with streptococcal profiles; consequently, g. vaginalis has been included in the api 20 strep data base.	1985	3874213
gardnerella vaginalis in urinary tract infections of immunocompromised patients.		1985	3874777
gardnerella vaginalis & associated aerobic bacteria in nonspecific vaginitis.		1985	3874825
phagocytosis and killing of gardnerella vaginalis by human neutrophils.	gardnerella vaginalis was ingested and killed by neutrophils in the presence of normal human serum. heat inactivation of the serum inhibited these processes. the opsonisation of some but not all g vaginalis strains was enhanced by immune rabbit serum. immune serum did not, however, enhance intracellular killing. blockade of the classical pathway of complement activation had no effect on the opsonic activity of human serum. these results suggest that the opsonisation, phagocytosis, and killing of ...	1985	3874884
laboratory identification of sexually transmitted diseases.	laboratory methods are used for the rapid identification of nine sexually transmitted diseases. some problems are inherent in those methods. alternate approaches can be used in the laboratory.	1985	3874959
importance of differential diagnosis in acute vaginitis.	acute vaginitis is one of the most common diseases seen in the practice of office gynecology. large survey studies of women with lower genital tract symptoms suggestive of vaginitis have demonstrated the presence of three major etiologic categories in acute vaginitis: (1) nonspecific vaginosis (gardnerella vaginalis), (2) vulvovaginal candidiasis (candida albicans), and (3) trichomoniasis (trichomonas vaginalis). effective treatment of acute vaginitis requires that an accurate diagnosis be estab ...	1985	3875290
[amine colpitis].		1985	3876973
vaginal discharge and gardnerella vaginalis. predisposing factors.	a total of 284 women in the reproductive years with vaginal discharge from which only gardnerella vaginalis (gv) had been isolated, entered a questionnaire study on the possible causal relation between presence of gv and type of menstrual hygiene, type of contraception, number of deliveries, infertility and number of sexual partners. a control group consisted of 225 women without vaginal discharge. the study showed that patients with gv significantly more frequently used tampons for menstrual hy ...	1985	3877329
microbiology of the lower genital tract in postmenarchal adolescent girls: differences by sexual activity, contraception, and presence of nonspecific vaginitis.	the prevalence of selected microorganisms in the lower genital tract in postmenarchal adolescent girls was assessed, including vaginal gardnerella vaginalis, group b streptococcus, lactobacillus, mycoplasma species, ureaplasma urealyticum, staphylococcus aureus, and yeast, and endocervical mycoplasma species, u. urealyticum, chlamydia trachomatis, neisseria gonorrhoeae, and trichomonas vaginalis. specific attention was focused on important sexually transmitted disease organisms, and differences ...	1985	3877803
predictive value of the "clue cells" investigation and the amine volatilization test in vaginal infections caused by gardnerella vaginalis.	although still controversial, an etiologic role of gardnerella vaginalis is imputed in vaginitis. besides isolation of the organism by culture, two alternative diagnostic procedures have been claimed to be useful: the investigation of "clue cells" in clinical specimens and the amine volatilization test or fishy odor perception in genital secretions. herein we report on the findings of the simultaneous use of g. vaginalis isolation, the clue cell test and amine volatilization perception in specim ...	1985	3878365
comparison of two different metronidazole regimens in the treatment of gardnerella vaginalis infection with or without trichomoniasis.	gardnerella vaginalis infection confirmed by culture was treated either by a 2 g dose or divided doses of metronidazole in 100 and 200 female patients respectively. both dosages were equally effective. we recommend a single dose of 2 g metronidazole in the treatment of gard. vaginalis infection, particularly when association with trichomoniasis is confirmed or suspected.	1985	3879249
isolation of gardnerella vaginalis from high vaginal swabs.	vaginal swabs from 2715 consecutive unselected women with vaginal discharge were examined for gardnerella vaginalis, candida albicans and trichomonas vaginalis. of 2715 women, 2043 had non-specific vaginitis and g. vaginalis was isolated from 269 cases (13.2%). thirty five of the strains were isolated together with c. albicans, eight with t. vaginalis, six with bacteroides species and three each with group b streptococcus and staphylococcus aureus. two hundred and sixteen (80%) of the isolates w ...	1985	3879398
a case of conjunctivitis in a neonate due to gardnerella vaginalis.	a case of conjunctivitis in a neonate caused by gardnerella vaginalis is described. the diagnosis was confirmed by examination of a gram-stained smear, isolation of the organism from the conjunctival swab, and also by response to treatment with chloramphenicol. the organism was probably derived from the mother's birth canal during delivery and the early rupture of membrane might be the predisposing factor.	1985	3879399
[clinical, diagnostic and management aspects in vulvovaginitis and pelvic inflammatory disease].		1985	3879641
[antimicrobial activity of nifuratel].		1985	3879754
gardnerella vaginalis: genitourinary pathogen in men.		1985	3883630
[amine colpitis, not only an esthetic problem: increased infection risk in labor].	in 76 women with non-specific vaginitis we could always isolate gardnerella vaginalis and several anaerobics, especially bacteroides species, in hgh counts. in 19 puerperae, bacteriologial examinations of the infected episiotomy wound yielded a spectrum of pathogens similar to that of non-specific vaginitis. in 74 per cent of the women with wound infection following episiotomy, non-specific vaginitis had either already been present before childbirth (and identified as gardnerella vaginalis vagin ...	1985	3884431
non-specific vaginitis: diagnostic features and response to imidazole therapy (metronidazole, ornidazole).	detailed quantitative aerobic, anaerobic, fungal and mycoplasma flora was obtained for 43 women presenting with complaints of vaginal discharge and malodour. clinical response was associated with eradication of the abnormal anaerobic flora, despite persistence of g vaginalis in nine (26%). topical imidazole therapy appeared to have some advantage over oral therapy. gram stains of vaginal swabs were found to be the most useful laboratory investigation.	1985	3887255
problems in specimen collection for sexually transmitted diseases.	laboratory methods for the diagnosis of sexually transmitted diseases (stds) are continuously undergoing improvement. it remains the responsibility of the clinician to become familiar with the tests available for the diagnosis of stds. those tests depend on obtaining clinical specimens from the proper site and on transporting them to the laboratory under satisfactory conditions.	1985	3894659
comparison of single-dose vs one-week course of metronidazole for symptomatic bacterial vaginosis.	in a prospective, single-blind, randomized study, a single 2-g dose of metronidazole was compared with a seven-day course of 500 mg given twice daily in the treatment of symptomatic vaginal discharge associated with gardnerella vaginalis. based on resolution of symptoms and on cultures negative for g vaginalis, 86% (40/46) of women treated with the single dose and 97% (35/36) of women treated with the seven-day course were considered cured at seven to ten days after treatment. evaluation at 21 d ...	1985	3894707
moxalactam versus clindamycin plus tobramycin in the treatment of obstetric and gynecologic infections.	the clinical efficacy of moxalactam versus clindamycin/tobramycin was evaluated in a comparative, randomized, prospective study. sixty patients were treated: 30 with moxalactam and 30 with clindamycin/tobramycin. there were 15 cases of tuboovarian abscess, 36 cases of severe pelvic inflammatory disease with peritonitis, eight cases of endomyometritis, and one wound abscess. aerobic and anaerobic cultures from the sites of infection yielded 441 microorganisms from 53 patients; an average of 8.3 b ...	1985	3895947
an office laboratory panel to assess vaginal problems.	in determining the cause of vaginal complaints, the routine use of four simple tests ("the vagina panel") enables the physician to identify pathogens (candida, gardnerella, trichomonas), pathologic processes (inflammation, estrogen deficiency) and, in most instances, a healthy vagina. time and money are saved. the specimens can be collected in one minute during a pelvic examination. the panel can provide the answers to eight essential questions in two minutes of observer time, with supplies cost ...	1985	3898791
the treatment of gardnerella vaginalis vaginosis: a randomized comparison of pivampicillin with metronidazole.	the efficacy of pivampicillin and metronidazole were compared in the treatment of gardnerella vaginalis associated bacterial vaginosis. in a multicenter trial 86 women were given pivampicillin (p) 700 mg twice daily for 6 days and 86 women received metronidazole (m) 400 mg three times daily for 7 days. at control, 2 weeks from the start of treatment, patients in group p showed the best clinical results, 77.9% in group p vs. 64.0% in group m (p = 0.066). p showed a higher clinical efficacy than m ...	1985	3898976
diagnostic value of clinical examination, direct microscopy, and culture in the gardnerella vaginalis syndrome.	in a general practice 467 women aged 15-49 years with vaginal discharge were consecutively examined in order to compare the diagnostic value in the gardnerella vaginalis syndrome of the clinical examination, direct microscopy of the vaginal secretion, and culture. we found significant correlations between all relevant combinations of the diagnostic methods. the predictive value of a positive test for the clinical examination, the microscopy, and the clinical examination combined with microscopy, ...	1985	3903905
treatment of the gardnerella vaginalis syndrome. a controlled, double-blind study comparing pivampicillin and metronidazole.	a double-blind, randomized, therapeutic study was carried out in 289 patients with vaginal discharge and growth of gardnerella vaginalis (gv) and no growth of neisseria gonorrhoeae, trichomonas vaginalis or candida. treatment consisted of either pivampicillin (pondocillin), 700 mg twice daily for seven days, or metronidazole, 500 mg twice daily for seven days. the effect was evaluated on the basis of the patient's statement and on the result of culture for gv immediately after end of treatment. ...	1985	3903906
in-vitro and in-vivo activity of metronidazole against gardnerella vaginalis, bacteroides spp. and mobiluncus spp. in bacterial vaginosis.	an open, randomized, culture-controlled clinical study was designed to compare the efficacy of a single 2 g dose of metronidazole (elyzol) with standard 7-day therapy in the treatment of bacterial vaginosis (bv). forty-one of 47 (87%) patients given the single dose and 30 of 33 (91%) given the 7-day treatment were found to be cured seven days after treatment. at final assessment, 24 of 34 (71%) patients given the single dose and 22 of 28 (79%) given the 7-day treatment remained cured. the two re ...	1985	3905748
[detection of gardnerella vaginalis in the pathogen spectrum of sexually transmissible diseases in vulvovaginitis].	gardnerella vaginalis, a sexually transmittable organism, is regarded as the indicator of the so-called "non-specific vaginitis". the isolation rate of g. vaginalis from 72 women attending our out-patient department during one year because of urogenital complaints was higher in pretreated than in untreated patients. in genital swabs taken from untreated patients, g. vaginalis could be isolated only in 17%, whereas this was observed in 38% of the specimens from women pretreated with various antim ...	1985	3907172
[bacterial vaginosis].		1985	3907521
adhesion of gardnerella vaginalis to vaginal epithelial cells: variables affecting adhesion and inhibition by metronidazole.	variables affecting the adherence of gardnerella vaginalis to human vaginal epithelial cells were examined in vitro. adherence depended on ph, with maximum attachment occurring between ph 5 and ph 6. preincubation of the bacteria at 56 degrees c for 30 minutes and ultraviolet irradiation resulted in a noticeable decrease in adherence. in contrast, adherence was not altered by preincubating the epithelial cells under these conditions. periodate oxidation of the vaginal cells caused an appreciable ...	1985	3910547
[pelvic inflammatory disease and nonspecific vaginitis].		1985	3911475
evaluation of gas-liquid chromatography for the rapid diagnosis of amniotic fluid infection: a preliminary report.	gas-liquid chromatography has been proposed as a possible tool in the rapid diagnosis of amniotic fluid infections. the analysis is based on the identification of specific organic acids derived from bacterial metabolism when organisms are present within the amniotic fluid. we retrospectively subjected 69 samples of amniotic fluid which had been obtained by transabdominal amniocentesis to analysis by gas-liquid chromatography. forty-seven samples were derived from patients who either were in prem ...	1985	3922227
[gardnerella vaginalis in routine cultures of material from the genital region].		1985	3923372
[isolation and identification of gardnerella vaginalis].	thirty-four strains of gardnerella vaginalis were studied. they were isolated from non specific vaginitis. a presumptive identification can be based on colonial morphology, gram stain characteristics, negative catalase and oxidase test. the differentiation of gardnerella vaginalis from other negative catalase coccobacilli is based on the acid formation of carbohydrates, enzymatic test, analysis of short chain volatile and non volatile end products of fermentation in glc. all gardnerella strains ...	1985	3931038
[prevalence of 7 microorganisms in abnormal vaginal secretions (vaginitis)].	seven microorganisms (n. gonorrhoeae, c. albicans, t. vaginalis, g. vaginalis, m. hominis, u. urealyticum and streptococcus of group b) have been assayed in genital samplings of 164 asymptomatic women (control group) and of 374 women suffering from abnormal vaginal secretions (vaginitis group). all these bacteria except group b streptococci were isolated in the vaginitis group more frequently than in the control group (p less than 0.01). the proportion of negative cultures for all tested bacteri ...	1985	3934750
in vitro adherence of lactobacillus species to vaginal epithelial cells.	because of the reported use of yogurt douches for the treatment of vaginitis, the adherence of lactobacillus species to normal human vaginal epithelial cells was tested by in vitro methods. l. acidophilus and l. bulgaricus isolated from three commercial yogurts were compared to l. acidophilus, l. fermentum, l. cellobiosus, and l. casei isolated from clinical specimens and from american type culture collection cultures. l. acidophilus isolated from lactinex tablets was also tested. no significant ...	1985	3934974
reverse camp phenomenon of gardnerella vaginalis (a note).	gardnerella vaginalis strains inhibit the haemolysis by listeria monocytogenes on human blood agar incubated in 5-10% co2 atmosphere or under anaerobic conditions.	1985	3939073
clinical comparison of an agar slide blood culture bottle with tryptic soy broth and a conventional blood culture bottle with supplemented peptone broth.	the roche septi-chek biphasic blood culture system with tryptic soy broth was compared with a conventional blood culture bottle with supplemented peptone broth in 6,956 paired blood cultures from adult patients. both systems were inoculated with equal volumes of blood (5 ml) and incubated aerobically (vented) for 2 weeks. more clinically important bacteria and fungi, including staphylococcus aureus, s. epidermidis, escherichia coli and other enterobacteriaceae, pseudomonas aeruginosa, and candid ...	1985	3998116
nonspecific vaginitis following sexual abuse in children.	nonspecific vaginitis, one of the most common causes of vaginitis in adults, is a polymicrobial infection in which vaginal anaerobes act synergistically with gardnerella vaginalis. the diagnosis is made by examination of the vaginal secretions for clue cells, the development of a fishy odor after the addition of 10% koh to vaginal secretions, and a vaginal ph greater than 4.5. to determine whether nonspecific vaginitis occurs in sexually abused children, we obtained vaginal washes from 31 abused ...	1985	4000776
[etiology of bacterial vaginosis (non-specific vaginitis)].	56 women who were diagnosed bioclinically as having a bacterial vaginal infection were studied, as were 35 women as a control group. the study was a semi-quantitative analysis of the vaginal bacterial flora, both aerobic and anaerobic. it shows that gardnerella vaginalis and anaerobic bacteria such as peptococcus, peptostreptococcus, bacteroïdes, veillonella and mobiluncus were associated in a statistically significant way with bacterial vaginitis. on the other hand lactobacilli were less freque ...	1985	4078248
[malodorous leukorrhea caused by gardnerella vaginalis vaginitis. biochemical study of vaginal secretions].		1985	2932731
the association of sexually transmitted diseases with cervical intraepithelial neoplasia: a case-control study.	thirty-three women with histologically confirmed cervical intraepithelial neoplasia (grades i to iii, with one case of microinvasive carcinoma) and 54 women without evidence of the disease were prospectively studied to determine the relationship of genital infection to cervical neoplasia. demographic and sexual data for patients and control subjects were collected, with standardized clinical and colposcopic evaluation by means of predefined diagnostic categories. cultures from the cervix were ex ...	1985	2982264
use of a sodium polyanetholesulfonate disk for the identification of gardnerella vaginalis.	several methods have been previously suggested for the presumptive identification of gardnerella vaginalis in clinical laboratories, but none is entirely satisfactory. we previously found that sodium polyanetholesulfonate (sps) inhibits g. vaginalis in blood culture media. we compared susceptibility to an sps-containing paper disk with beta-hemolysis on human blood agar, hippurate hydrolysis, and inhibition by alpha-hemolytic streptococci for identification of 62 previously confirmed g. vaginali ...	1985	2982910
effect of sodium polyanetholesulfonate and gelatin on the recovery of gardnerella vaginalis from blood culture media.	sodium polyanetholesulfonate (sps) is used as a routine supplement to blood culture media to enhance recovery of microorganisms, but it inhibits the growth of peptostreptococcus anaerobius, neisseria meningitidis, neisseria gonorrhoeae, and streptobacillus moniliformis. comparative clinical blood culture studies at the university of colorado hospital suggested that sps also inhibits the growth of gardnerella vaginalis. we inoculated 16 blood culture isolates of g. vaginalis into 11 blood culture ...	1985	2987298
sodium polyanethol sulphonate discs to identify gardnerella vaginalis.		1985	2991122
sodium polyanetholesulfonate in the identification of gardnerella vaginalis.		1985	2993355
the in-vitro activities of enoxacin and ofloxacin compared with that of ciprofloxacin.	the in-vitro activities of enoxacin and ofloxacin were compared with that of the other new 4-quinolone, ciprofloxacin. all three compounds were highly active against enterobacteriaceae, haemophilus influenzae and neisseria gonorrhoeae (mics mostly less than 1 mg/l). the other gram-negative aerobes tested were in general less susceptible, though for acinetobacter and pseudomonas species (including aeruginosa) mics seldom exceeded 8 mg/l. ofloxacin and ciprofloxacin were more active against gardne ...	1985	3159712
[vaginitis due to gardnerella vaginalis in a university medical service].	between august 1983 and june 1984, a total of 363 women were studied who had been referred to the medical service of the school of bacteriology and laboratory clinic of the university of antioquia, medellin, colombia, for obtaining vaginal cytology. they either had or did not have vaginal discharge. the smears were tested for gardnerella vaginalis and trichomonas vaginalis. the majority of the patients were in the third, fourth, and fifth decades of their lives: 51%, 24.5%, and 14%, respectiv ...	1985	12292701
vaginal carriage of anaerobic motile curved rods: relation to contraceptive practice, common pathogens, signs and symptoms.	the carriers of a species of anaerobic motile curved rods, often seen in cases of bacterial vaginosis, were compared with matched controls with respect to type of contraception, current symptoms and signs, and diagnosis of sexually transmitted disease (std). 65 carriers and 72 controls were ascertained from a std clinic. the anaerobes were demonstrated by phase contrast microscopy in a wet vaginal smear in 17.8% of 366 consecutive admissions. these organisms are difficult to culture, but are ...	1986	12281325
activity of pefloxacin and thirteen other antimicrobial agents in vitro against isolates from hospital and genitourinary infections.	the in-vitro activity of the quinolone derivative pefloxacin was compared with that of three other quinolones, five beta-lactam antibiotics and three aminoglycosides against 367 isolates from hospital patients and from out-patients with genitourinary infections. mic90 of pefloxacin and norfloxacin for each strain was the same; that of ciprofloxacin was a little lower. all strains except escherichia coli were resistant to nalidixic acid. pefloxacin was highly active against staphylococcus aureus ...	1986	3460983
the in-vitro activity of ci-934 compared with that of other new 4-quinolones and nalidixic acid.	the in-vitro activity of ci-934, a new 4-quinolone compound, was compared with that of the other new 4-quinolones, enoxacin and ciprofloxacin, and also with that of nalidixic acid. ci-934 was more active than any of the other 4-quinolones tested against gram-positive aerobic organisms including staphylococcus aureus (mics 0.06-0.25 mg/l), beta-haemolytic streptococci (mics 0.12-0.5 mg/l), streptococcus pneumoniae (mics 0.25-0.5 ml/l), viridans streptococci (mics 0.06-0.5 mg/l) and most enterococ ...	1986	3463557
the comparative in-vitro activity of eight newer quinolones and nalidixic acid.	the in-vitro antibacterial activity of nalidixic acid and the 4-quinolones, ciprofloxacin, norfloxacin, enoxacin, ofloxacin, pefloxacin, a-56619, a-56620 and ci-934 was assessed by determination of mics. the 4-quinolones were all highly active against most isolates of enterobacteriaceae, including nalidixic acid-resistant strains. ciprofloxacin (mics 0.002-2 mg/l) was the most active and a-56619 (mics 0.008-32 mg/l) was the least active. a-56619, a-56620, ofloxacin, ciprofloxacin and ci-934 were ...	1986	3468100
treatment of bacterial vaginosis with an acid cream: a comparison between the effect of lactate-gel and metronidazole.	bacteriological isolation of anaerobes, gardnerella and lactobacilli was carried out in a group of 62 women with the diagnosis bacterial vaginosis and 42 control women. lactobacilli were the predominant organisms in the control group whereas anaerobes dominated the flora in bacterial vaginosis patients. lactate-gel (ph 3.5, 5 ml) inserted into the vagina daily for 7 days is as effective as oral metronidazole, 500 mg twice daily for 7 days. the women in both groups became symptom-free and objecti ...	1986	3485071
the treatment of gardnerella vaginalis infection in general practice.		1986	3485279
etiology of cervical inflammation.	we studied the relationships of selected microbial, clinical, demographic, and behavioral variables to mucopurulent cervicitis in two clinical settings, a sexually transmitted disease clinic and a student health clinic. from each clinic, we studied a group of women referred for suspected mucopurulent cervicitis and a representative sample of other women attending the clinic. after the women were stratified by patient group and summary odds ratios for all groups were obtained, mucopurulent cervic ...	1986	3485379
tioconazole 2% cream in the treatment of trichomonas vaginalis or mixed vaginal infections.	twenty patients with documented t. vaginalis infections, six of whom were simultaneously infected with c. albicans and one with g. vaginalis, were treated topically (intravaginally) once daily with 5 g of 2% tioconazole vaginal cream (trosyd, pfizer) for 3 consecutive days in an open, non-comparative study. at the first follow-up visit (about 7 days post-treatment), 95% (19/20) of the patients were cured; 95% (18/19) of patients remained cured with respect to the baseline infection at the long-t ...	1986	3485546
gardnerella vaginalis and mosaic colposcopic pattern of the cervix: casual or causal association?	we made a retrospective study of the flora found in the vaginal smears of sexually active women who presented with a mosaic colposcopic pattern of the uterine cervix in an attempt to study some of its epidemiologic factors. of the 195 cervicovaginal cytologies of patients with mosaic, 61 revealed an abnormal flora (31.2%) while of the 9,856 patients without mosaic, only 2,234 cytologies had an abnormal flora (22.7%) demonstrating a statistically significant higher frequency (p less than 0.0001) ...	1986	3485553
gardnerella vaginitis--a guide to identification and management for the practitioner.		1986	3485708
diagnosis of gardnerella vaginalis infection by an enzyme-linked immunosorbent assay.		1986	3486120
episiotomy wound infection due to gardnerella vaginalis.		1986	3487451
amoxycillin, augmentin and metronidazole in bacterial vaginosis associated with gardnerella vaginalis.		1986	3487499
gardnerella vaginalis carriage in male patients.	urethral discharge from 579 consecutive men with non-gonococcal urethritis (ngu) was examined for gardnerella vaginalis. the organism was isolated from nine patients (1.5%). of these, one patient had a probable ngu due to g. vaginalis which is an extremely rare occurrence. the remaining eight patients were carriers of g. vaginalis. the prevalence rate of g. vaginalis in 150 randomly selected men without urethritis was five percent.	1986	3488607
[symptomatic and asymptomatic vaginitis. microbiological, clinical and therapeutic aspects].		1986	3488870