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failure to consult specialist. 20051173090
[an analysis of the afrikaans-speaking child's two word sentences]. 2005551534
the role of the surrounding tissue in the propagation of waves through the arterial system.a theoretical analysis of the flow in arteries is presented, taking into consideration the role played by the surrounding tissues in determining the speed of propagatoion and the damping of the blood pressure pulse. this study was undertaken (a) to exhibit a method of computing the flow properties with a more nearly accurate model, (b) to see if the displacement on the skin would be related to the arterial wall displacement, and hence to pressure, velocity and flow rate of blood in the artery, a ...20051231056
[initial experiences with a self-expanding metal stent in malignant ureteral compression].self-expanding metallic stents for the treatment of hydronephrosis were implanted in 12 ureters with malignant compression in 10 patients. in 3 ureters the stents were introduced percutaneously by a transrenal route; in 8 ureters introduction was transurethral and in one ureter by a combined route. patency rate after 6 months was 90.9%. in all cases the stent was able to withstand pressure by the tumour for the remainder of the patient's life. in one patient there was incrustation of both stents ...20051370762
[immunological in vitro tests in the assessment of specific cellular reactivity in tuberculosis]. 20051079782
[scheele research and acclaim in travels to other countries. the 250th birthday of carl wilhelm scheele]. 20051287672
xeromammography at a community hospital. a year's experience. 20051183210
a volumetric assessment of pollen levels in the air of ann arbor, michigan. 20051196148
[clinico-morphological signs of different forms of destructive pancreatitis].clinicomorphological comparisons in 434 cases of destructive pancreatitis showed that macroscopic signs of destruction develop in the first 12 hours from the onset of the attack. the elaborated criteria make it possible to evaluate the main morphological components of destructive pancreatitis--pancreonecrosis proper, parapancreatitis, peritonitis, and "polyvisceritis" and to use therapeutic measures on an individual basis.20061779556
rural advanced practice nurses: a decade of growth. 20061764326
rediscovering wormwood: qinghaosu for malaria. 20061347342
study of acute intraoperative suprachoroidal hemorrhage.acute intraoperative suprachoroidal hemorrhage or effusion (aish) was studied in a prospective manner over the past three years. in a general cataract surgery population of 2,523 patient eyes, 15 (0.6%) experienced an aish. results of a specific surgical management technique are presented. surgical control of the aish consisted of immediate closure of the incision and application of pressure directly to the eye. this tamponades the effusion or hemorrhage, which allows coagulation and completion ...20061403754
acute myocardial infarction after blunt chest trauma in young people: need for prompt intervention.we describe four cases of acute myocardial infarction in young patients, secondary to blunt chest trauma. one case was treated with intracoronary thrombolysis and angioplasty, two cases received systemic thrombolysis, and the last one did not have any reperfusion therapy. the coronary angiograms of the left anterior descending artery showed thrombosis in two cases, coronary dissection in one case, and no morphological lesions in the other. we encourage the early performance of angiographic studi ...20061764738
[fundus plication with or without proximal selective vagotomy?].the aim of this study was to determine the influence of proximal gastric vagotomy on the outcome after fundoplication. of 141 patients operated on for reflux disease between 1972 and 1988, 53 had fundoplication alone (group a) and 88 fundoplication combined with proximal gastric vagotomy (group b). the two groups were similar with regard to the severity of the reflux disease (esophagitis: a 69%, b 73%) but had a different incidence of concomitant ulcer disease (a 2%, b 55%). after a mean follow- ...20061621082
network of signal transduction pathways involving lipids: protein kinase c-dependent and -independent pathways. 20061636498
carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i.the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ...20061525184
"raynaud's disease" in migraineurs: one entity or two?two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ...20061446993
the carpal tunnel syndrome: part ii.the carpal tunnel syndrome is a compression of the median nerve within the carpal tunnel with very specific signs and symptoms. anatomical dissection of 156 wrists is presented and then the authors compare their findings with the findings of other investigators. the purpose of this article is not to present results but rather to discuss the anatomic entities involved with the syndrome and to present the open treatment modality.20061550309
ontario's proposed consent laws: 1. consent and capacity, substitute decisions, advance directives and emergency treatment. 20061544072
[psoriasis and progressive multifocal leukoencephalopathy in aids]. 20061475452
the clinical engineer as medical laser safety officer. 20061393206
expression of her2/neu oncogene product p185 in correlation to clinicopathological and prognostic factors of gastric carcinoma.the expression of the her2/neu gene product p185 was retrospectively analyzed in 58 patients with gastric carcinoma. the results were correlated to various clinicopathological and prognostic factors. positive membrane staining for p185 could be detected in 38% of the patients (22/58). membrane staining was significantly greater in well and moderately differentiated tumors of the intestinal type when compared with poorly differentiated lesions and carcinomas of the diffuse type (p less than 0.01) ...20061352299
diagnostic value of some matrix components.although most diagnostic markers lie within the cell, a few are found in the matrix. well-known examples of these are amyloid filaments and fibrous long-spacing collagen (luse body). perhaps not so well-known are the diagnostic values of anchoring fibrils and microvillus-matrix associations. the latter two form the subject of this paper.20061557821
chronophysiology and ambulatory monitoring instrumentation. 20062242512
design and inhibitory properties of synthetic bowman-birk loops.a cyclic tridecapeptide based on the sequence of an anti-tryptic loop of a bowman-birk inhibitor was synthesized, and demonstrated to be active as an inhibitor of trypsin. molecular modeling of this sequence suggested an improved sequence which demonstrated an order of magnitude improvement in the inhibitory constant.20061446974
report from a national cancer institute (usa) workshop on quality of life assessment in cancer clinical trials.to promote the inclusion of quality of life (qol) end-points in clinical research on cancer, the national cancer institute (usa) sponsored a workshop on qol assessment in cancer clinical trials in july, 1990. experts in clinical trials and qol research formed four working groups to identify current areas of cancer treatment in which qol end-points are most important; to discuss methodologic problems in qol assessment; to address common problems in implementing clinical studies with qol end-point ...20061363776
aging and immunity.the function of the immune system peaks at around puberty and gradually declines thereafter with advance in age. the age-related decline of immunological function primarily occurs in the t cell-dependent immune system and is generally associated with increase in susceptibility to infections as well as in incidence of autoimmune phenomena in the elderly. the age-related change in t cell-dependent immune functions can be ascribed to the physiological thymic atrophy which starts in an early stage o ...20061449050
determination of ring- and n-substituted amphetamines as heptafluorobutyryl derivatives.an improved derivatization method for analysing 12 ring- and n-substituted amphetamine-derivatives in body fluids or seized materials by gas chromatograph combined either with mass spectrometer, electron capture or nitrogen phosphorus detector is presented. heptafluorobutyric anhydride is used as derivatization reagent. no heating or standing period is needed in this procedure. most of the drugs considered were distinguishable from each other according to their retention times and all of them ac ...20061855720
determination of ring- and n-substituted amphetamines as heptafluorobutyryl derivatives.an improved derivatization method for analysing 12 ring- and n-substituted amphetamine-derivatives in body fluids or seized materials by gas chromatograph combined either with mass spectrometer, electron capture or nitrogen phosphorus detector is presented. heptafluorobutyric anhydride is used as derivatization reagent. no heating or standing period is needed in this procedure. most of the drugs considered were distinguishable from each other according to their retention times and all of them ac ...20061855720
[planning in the health field]. 20061553488
quantitative gamma-ray computed tomography of the radius in normal subjects and osteoporotic patients.a new design of gamma-ray computed tomography (ct) scanner was used to measure bone density in 516 normal adults and in 116 female patients with osteoporotic fractures. trabecular bone density (tbd) was measured for a core of the ultradistal radius; cortical bone mass per unit length (mls) and mass per unit volume (mvs) were computed for the radius shaft. tbd, mls and mvs peaked at the age of about 40 in females and fell by 32%, 15% and 24%, respectively, by the age of 65. in males, tbd decrease ...20062242474
comparing clinical tests of visual loss in cataract patients using a quantification of forward light scatter. 20061794427
effects of norethisterone on pressor response to angiotensin ii in men.we examined the effects of norethisterone and/or mestranol on the pressor response to angiotensin ii in 20 healthy men.20061635747
caution advised when changing to new therapies. 20061458280
eccrine hidrocystoma: two cases of robinson and smith types.two cases of eccrine hidrocystoma, one of which is a "classic" robinson type and the other a smith type, were reported. the walls of both cysts consisted mainly of two layers of flat or low cuboidal epithelial cells with eosinophilic cytoplasm. immunostaining for s-100 protein was negative in the cells of the cyst wall of the robinson type and only weakly positive in the inner luminal layer of the smith type. electron microscopically, the smith type showed double-layered cuboidal lining and cell ...20061401509
[transient, prolonged, combined sicca syndrome of the eyes and mouth. occurrence along with a common cold in an 8-year-old girl].a girl of eight years fell ill with signs of common cold and bronchitis. already on the second day of illness, before any treatment was started, she showed symptoms of a sicca-syndrome, beginning in the eyes, later the mouth. ophthalmologic examination showed keratitis filiformis, histology of the salivary glands in the mucosa of the mouth was normal. local substitution therapy led to subjective improvement. the disorder of secretion persisted for four months only, then rapid restitutio ad integ ...20061435804
peripheral stem cells made to work. 20061347341
what role will residency education take in the profession by the year 2000?residency education has enjoyed relatively slow but steady growth since its inception in the mid-1970s. a certain segment of recent graduates consider graduation from optometry school as entry level and perceive the need for additional clinical education. the creation of new residency programs and the expansion of existing ones may occur in a variety of settings. for residency education to realize its full potential, optometry must seek federal support for post-graduate clinical education. this ...20061447463
schizophrenia: gender and familial risk.the morbid risks for schizophrenia and any nonaffective psychosis in the first degree relatives of male and female schizophrenic probands were compared utilizing cox proportional hazards models. the schizophrenic probands (275 male; 106 female) were drawn from a larger sample of hospitalized patients obtained by systematically screening all psychiatric admissions to 15 facilities over a six-year period. proband diagnoses (dsm-iii) were based on a direct assessment of the patient and a review of ...20061560406
adoptive immunotherapy of cancer: biological response modifiers and cytotoxic cell therapy.immunotherapy has been developed for the treatment of metastatic cancers refractory to conventional therapies. immunotherapy utilizes immune cells and/or biological response modifiers (brms) to induce an anti-tumor response mediated by the patient's immune system. brms, including lymphokines and cytokines, are used as single agents or in combination for cancer therapy. some brms, particularly interleukin 2 (il-2), can activate and expand in vitro lymphocytes with anti-tumor reactivity which will ...20061524952
[local meeting series--a model for continuing education of the general practice staff].during the period january 1987 to june 1990 28 educational afternoon meetings were held for the office staff and nurses in general practice in bodø, as well as for the nurses in the bodø emergency clinic/service. office staff and nurses in the occupational health service were also invited, bringing the number up to 42. on average 40.0% of the invited persons attended the meetings. each meeting lasted 2 hours. the number attending the last meetings was so few that the series was discontinued. how ...20061557764
[expert assessment of asbestos-induced lung damage].asbestos is a mineral of special technical properties and therefore used in many products all over the world. the inhalation of asbestos causes chronic inflammation of lung--the asbestosis--and pleura--pleuraplaques and pleuritis--and is responsible for mesothelioma and lung cancer. under normal conditions the diagnosis asbestosis is easy because of the typical x-ray findings and the history of intensive exposure of asbestos. in rare conditions the history of exposure is uncertain and the diagno ...20072139990
doppler flow velocities in single umbilical arteries.fetal compromise has been associated with an umbilical artery waveform pattern of low or absent diastolic velocity relative to systolic velocity. fetuses with single umbilical arteries have an increased risk of major malformations, mortality, retarded fetal growth, and prematurity. in this study doppler flow velocities were obtained in 13 fetuses (four twin fetuses and nine singletons) with a single umbilical artery. five (38%) fetuses, consisting of four singletons and one twin, had anomalies. ...20071951526
[hydatidosis of the cranial vault. two case reports].the authors report 2 cases of echinococcosis of the cranial vault, an extremely rare localization of hydatid disease. the parietal bone was involved in one case and the occipital bone in the other. the authors discuss the mechanism and classification of cranial vault echinococcosis. the clinical signs of the disease as well as its radiological appearances and especially its very characteristic ct scan appearances are studied in relation to the literature.20072234264
the sojourn time and its use in pharmacology.a short review on some pharmacokinetic parameters (mean residence time, sojourn time, transit time) is given in relation to compartmental models and some examples and application are discussed. in particular the use of the sojourn time is suggested because this parameter can give useful informations when comparing the pharmacokinetics of different drugs or in pharmacodynamics.20071820930
systematized progradient multiple combined melanocytic and blue nevus.a 44-year-old woman was diagnosed as having unilateral multiple progradient pigmented macules and papules of the upper extremity and adjacent part of the back. microscopically increased amounts of melanin and melanocytes in the basal layer of the epidermis in the early developmental stage of macules were seen. combinations of blue nevus with junctional or compound nevus or with a simple proliferation of melanocytes in the epidermis were present in the papules. the question of prognosis is discus ...20071867359
measuring cholesterol. a handbook for out-patient clinics and laboratory personnel. 20072100407
nasopharyngeal carcinoma with spinal secondaries.nasopharyngeal carcinoma has been reported to have a higher incidence of distant metastases as compared to other head and neck cancers. distant metastases of nasopharyngeal carcinoma has been reported in the bones, lungs, liver, distant lymph nodes, brain and porta hepatis. this report presents a case of nasopharyngeal carcinoma with secondaries in the extradural space at the thoracic level of the spinal cord which hitherto has been an unreported site.20071919352
results of cochlear implants in children.about 700 children throughout the world have been implanted to date. placing a cochlear implant represents no particular problem in the child. the incidence of complications is not high, being of about the same proportion as that in the adult. to obtain the best results, the selection of patients must be correct and carried out by a multi-disciplinary team of specialists, while the operated child must be subject to regular and intensive rehabilitation. the results appear to have become more sati ...20071950547
introduction to endoscopic therapy for bleeding peptic ulcers. 20072242806
controversies in otoplasty.in the last 30 years many surgeons, plastic as well as ent surgeons, have been increasingly concerned with the correction of protruding ears. there are many controversial points of view regarding the preferable surgical approach. each surgeon is claiming to find the best solution to this specific issue. to find an acceptable solution, various techniques tackling all the components of the deformity are screened. my preferred technique for the reconstruction of prominent ears, using the best of se ...20071950548
familial predisposition for herniation of a lumbar disc in patients who are less than twenty-one years old.the parents of sixty-three patients who were less than twenty-one years old and who had operatively confirmed herniation of a lumbar disc were interviewed regarding a history of sever back pain, sciatica, and herniated disc, to determine whether aggregation of herniation of a lumbar disc occurs in families of patients in this young age-group. the parents of sixty-three additional patients who had a non-spinal orthopaedic diagnosis (control group) were matched for age and sex with the study group ...20071824705
major histocompatibility complex (mhc) class ii region in humans. 20071855818
the first 2 years of the gambian national cancer registry.we describe the creation, and the first 2 years experience, of the gambian national cancer registry. the major problems involved in the creation of such a registry in a developing country are discussed. the data accumulated show a low overall rate of cancer incidence compared to more developed parts of the world and indicate that the prevalent cancers, hepatoma, carcinoma of the cervix and lymphoma, are likely to be due to infectious agents. it is hoped that immunisation of children under one ye ...20072223583
the first 2 years of the gambian national cancer registry.we describe the creation, and the first 2 years experience, of the gambian national cancer registry. the major problems involved in the creation of such a registry in a developing country are discussed. the data accumulated show a low overall rate of cancer incidence compared to more developed parts of the world and indicate that the prevalent cancers, hepatoma, carcinoma of the cervix and lymphoma, are likely to be due to infectious agents. it is hoped that immunisation of children under one ye ...20072223583
predominant expression of lambda light chain in adult cases with non-t-cell acute lymphocytic and chronic myelogenous leukemia in lymphoid blast crisis.the authors investigated cytoplasmic immunoglobulins of the leukemic cells from 20 adult cases with non-t-cell acute lymphocytic leukemia (all) and from three cases with chronic myelogenous leukemia in lymphoid blast crisis using immunoelectron microscopy. they also studied these cases using various monoclonal antibodies. of the 23 examined cases, nine were negative for both heavy and light chains of immunoglobulins; the authors defined these as common all. two cases were positive for the mu cha ...20071906773
body composition of low-birth-weight infants determined by using bioelectrical resistance and reactance.we tested the hypothesis that bioelectrical resistance and reactance are indices of total body water (tbw) and extracellular water (ecw), respectively. infants less than 2500 g in birth weight were studied while less than 24 h old and at 4-7 d of age. tbw (n = 32) was measured by h2(18)o dilution and ecw (n = 34), by bromide dilution. measurements were made by using an impedance plethysmograph from each of four electrode pairs. bioelectrical resistance correlated inversely with tbw (r = -0.683). ...20071858693
two years as a veterinarian in africa: thoughts and observations. 20071874661
[menopausal hospital units]. 20071821060
the 1990 merck frosst award. ischemic and reperfusion injury in the heart. cellular mechanisms and pharmacological interventions.reperfusion in the heart represents an important form of tissue injury, particularly in view of the emerging importance of reperfusion protocols aimed at salvaging the ischemic myocardium. both the manifestations and the causes of reperfusion injury are multifold. with respect to the former, reperfusion injury can be characterized by various abnormalities including development of arrhythmias, contractile dysfunction, ultrastructural damage as well as various defects in intracellular biochemical ...20071913318
[the hemodynamic effects of isradipine and nifedipine in hypertension].hemodynamic effects of isradipine and nifedipine in hypertension myocardial wall tension is an important determinant of the oxygen demand, the function and the degree of hypertrophy of the left ventricle. myocardial wall tension should be influenced more favourably by a non-cardiodepressive antihypertensive than by a potentially cardiodepressive one. therefore, we investigated the effects of an intravenous infusion of the calcium antagonists isradipine (i; 0.4 mg; 3,5-pyridinecarboxylic acid, 4- ...20071839125
[derivative spectroscopy and its use in sanitary hygiene control].an analytical method is developed for defining the residual quantities of rodenticide "brodifacoum" (talon) used in the control of harmful field rodents and especially for species microtus. the method is based on extracting the pesticide with chloroform and making use of spectrophotometry in the ultraviolet field in intervals 340-240 nm. the second derivative of the absorption is utilized as well as the band with maximum 288 nm and minimum 228 nm. the peak height in this interval is in proportio ...20072099444
a comparative study for fiberoptic and video endoscopic determination of the extent in minimal changes of gastric mucosa using indigo dye spraying.the image resolution of fiberoptic and video endoscopy was compared in a series of patients with early gastric cancer. eighteen patients were divided into two groups. one group of patients (n = 9) was evaluated with fiberoptic endoscopy while the second group (n = 9) was evaluated using video endoscopy. the extent of cancer invasion, with special attention to size, shape and type of the lesions, was evaluated in each patient. attempts were also made to identify the proximal and distal limits of ...20072374986
hospital outbreak of scabies stemming from two aids patients with norwegian scabies. 20071971073
regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action.the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ...20071852316
[laser therapy in acute nonspecific epididymo-orchitis].laboratory experiments were followed by clinical investigations of low-intensity laser radiation (lr) feasibility in therapy of acute epididymo-orchitis. a total of 117 patients aged 15-68 were treated with mild, moderate and severe scrotal inflammation. the response was compared to that in physiotherapy (54 patients) and early surgery (40 patients). it proved higher by 38.5%, the proportion of the treatment failure diminished from 22.2% for conservative and 15% for surgical management to 7.7%. ...20072063504
imaging of the temporomandibular joint in juvenile rheumatoid arthritis. 20071932822
when to do a lumbar puncture in a neonate. 20082650636
occupational medicine. organizational behavior.work flow and the administrative processes by which it is controlled are fundamental in shaping the realities of the organization as a system of relationships. organization is technology in the broadest sense: processes, procedures, policies, controls, formal authority structures, and techniques. among groups or organizations, it is unusual for changes in sentiment to precede action or organizational rearrangements. technology and structure must be changed first. this chapter has outlined organi ...20082644717
hypothalamic vasopressin mrna levels in mice are decreased after chronic ethanol ingestion.vasopressin mrna levels in the supraoptic and paraventricular nuclei of the hypothalamus, measured by in situ hybridization with a 35s-labeled rna probe, were decreased by nearly 50% in c57bl/6ncr mice that had ingested an ethanol-containing diet for 7 days, and were tolerant to and physically dependent on ethanol. at 24 h after withdrawal, vasopressin mrna levels in the supraoptic nucleus were still decreased, while levels in the paraventricular nucleus returned toward control values. although ...20082253699
two cytochrome p-450 isoforms catalysing o-de-ethylation of ethoxycoumarin and ethoxyresorufin in higher plants.the o-dealkylating activities of 7-ethoxycoumarin o-de-ethylase (ecod) and 7-ethoxyresorufin o-de-ethylase (erod) have been fluorimetrically detected in microsomes prepared from manganese-induced jerusalem artichoke tubers. cytochrome p-450 dependence of the reactions was demonstrated by light-reversed co inhibition, nadph-dependence, nadh-nadph synergism and by use of specific inhibitors: antibodies to nadph-cytochrome p-450 reductase, mechanism-based inactivators and tetcyclasis. apparent km v ...20082241905
effects of constraint on the oscillatory pattern of endosonic files.when operated in air, the transverse oscillation of the endosonic file exhibits a series of nodes and antinodes along its length with the greatest displacement amplitude occurring at the unconstrained tip. endosonic files of varying design, length, and thickness exhibit differences in their oscillation. preliminary work has revealed that the endosonic file is susceptible to constraint when working within the root canal and a model system was designed to investigate this problem. the constraining ...20082607288
relationship between religiousness and trait anxiety: factor or artifact? 20082608843
[clinical study of osteoporosis]. 20082614196
[use of the crystalline film method in the diagnosis of pathological processes]. 20082409338
a long term treatment with a venotropic drug. results on efficacy and safety of daflon 500 mg in chronic venous insufficiency.drugs for long term administration have to prove their efficacy and safety. previously published double blind controlled studies (from single dose to two months treatment) have already demonstrated the phlebotropic activity of daflon 500 mg in chronic venous insufficiency (cvi). the aim of the study was to investigate the safety of this agent during one year of continuous administration. two-hundred and fifteen out-patients suffering from cvi received daflon 500 mg, 2 tablets per day. therapeuti ...20082632651
spontaneous insertion of integral membrane proteins into preformed unilamellar vesicles. 20082593844
the treatment of urinary incontinence in adults.the inability to control urination is a condition that causes a loss of dignity in persons of all ages. it is a distressing condition that affects a large number of young women and becomes a most distressing problem for the older adult. this article deals with the general treatment approaches for the urinary incontinent patient, including drug therapy, surgical intervention and mechanical devices. special emphasis is placed on nursing measures, including behavioral intervention approaches for th ...20082662059
autologous blood stem cell transplantation. 20082565063
[off. gesundh.-wes. 50 (1988) 670-677, "legal-social observations on prostitution in relation to aids and aids-complex by e. quambusch]. 20082528100
[combination chemotherapy with cis-diamminedichloroplatinum (cddp) and other anticancer agents for patients with advanced esophageal cancer].combination chemotherapy with cis-diamminedichloroplatinum (cddp) and other anticancer agents was performed in patients with advanced esophageal cancer. from july 1982 to september 1984, 16 patients were entered into this study and divided into two regimens. in regimen i, 5 patients were treated with a daily dose of 20 mg cddp and 10 mg peplomycin for five consecutive days and 10 mg mitomycin c on the first day. this course was repeated 2 or 3 times every 4 weeks. as for evaluation, 1 pr (20%) a ...20082408579
cooperativity of carbohydrate moiety orientation and beta-turn stability is determined by intramolecular hydrogen bonds in protected glycopeptide models.the 2,3,4,6-tetra-o-acetyl-beta-d-gluco-, and beta-d-galactopyranosides, as well as approximately 4:1 anomeric mixtures of alpha- and beta-mannopyranosides of boc-x-y-nhch3 dipeptides (x-y = pro-ser, pro-d-ser, val-ser, val-d-ser, and gly-ser) have been synthesized. cd and ir spectroscopic studies were performed to characterize the conformation of the glycosylated peptide backbone and examine the possible formation of intrapeptide and glycopeptide intramolecular h-bonds. it was found that o-glyc ...20082386806
stepwise development of chromosomal abnormalities in angioimmunoblastic lymphadenopathy.cytogenetic studies of lymphoproliferative diseases, such as angioimmunoblastic lymphadenopathy (aild), may provide a clue to the understanding of tumor development. angioimmunoblastic lymphadenopathy may evolve from a nonmalignant lymphoproliferation into a peripheral t-cell lymphoma or even into a high-grade b-cell lymphoma and thus offers the chance to observe cytogenetic changes during lymphoma development. we report the cytogenetic findings in 24 cases of aild. they are discussed together w ...20082253183
[the psychotic anxiety scale (pas). evaluation of inter-rater reliability and correspondence factorial analysis].we recently proposed the first scale for evaluating anxiety in psychotics: the "psychotic anxiety scale" (pas). the first version of this scale was tested in 45 psychotic patients. the multiple correspondence factorial analysis revealed that 4 factors account for respectively 50%, 18%, 17% and 10% of the variance. this scale thus evaluates anxiety along 4 axes: severity of the symptomatology, evolution in time, hetero-aggressiveness and self-aggressiveness. this analysis supports the hypothesis ...20082612427
[the psychotic anxiety scale (pas). evaluation of inter-rater reliability and correspondence factorial analysis].we recently proposed the first scale for evaluating anxiety in psychotics: the "psychotic anxiety scale" (pas). the first version of this scale was tested in 45 psychotic patients. the multiple correspondence factorial analysis revealed that 4 factors account for respectively 50%, 18%, 17% and 10% of the variance. this scale thus evaluates anxiety along 4 axes: severity of the symptomatology, evolution in time, hetero-aggressiveness and self-aggressiveness. this analysis supports the hypothesis ...20082612427
percutaneous excimer laser coronary angioplasty. 20082570302
a mucin containing the x, y, and h type 2 carbohydrate determinants is shed by carcinoma cells.monoclonal antibody br 15-6a directed to the y carbohydrate determinant (fuc alpha 1----2gal beta 1----4glcnac(3----1fuc) beta 1----3gal beta 1----4glc beta 1----1cer) reacted with the cell surface and conditioned media of colorectal and breast carcinoma cell lines. double determinant immunoassays using br 15-6a as detector antibody showed that the y determinant is part of a high molecular weight mucin that coexpressed other carbohydrate antigens based on a type 2 chain (x, h type 2). type 1 cha ...20082442094
phytochrome from the green alga mesotaenium caldariorum. purification and preliminary characterization.a method to purify the phytochrome photoreceptor from the unicellular green alga mesotaenium caldariorum is presented. preparative scale formation of algal protoplasts and controlled osmotic cell lysis have permitted separation of intact organelles from the phytochrome-enriched soluble protein fraction. we have utilized the observation that red light-absorbing (pr) and far-red light-absorbing (pfr) forms of phytochrome are differentially retained on an anion exchange matrix to purify m. caldario ...20082324111
grading white matter lesions on ct and mri: a simple scale.we developed and tested a simple three-point scale for grading white matter lesions in anterior and posterior regions of the brain. twenty four ct scans and 24 mri scans were separately judged by 11 and five observers, respectively, on the presence and severity of white matter lesions. the observers were radiologists and neurologists. for ct scans, these periventricular changes were graded according to their extent as absent, or partly involving the white matter, or extending up to the subcortic ...20082292703
[the place of osteosynthesis using compression-distraction equipment in treating diaphyseal fractures of long tubular bones]. 20083714232
diffusion regulated growth characteristics of a spherical prevascular carcinoma.recently a mathematical model of the prevascular phases of tumor growth by diffusion has been investigated (s.a. maggelakis and j.a. adam, math. comput. modeling, in press). in this paper we examine in detail the results and implications of that mathematical model, particularly in the light of recent experimental work carried out on multicellular spheroids. the overall growth characteristics are determined in the present model by four parameters: q, gamma, b, and delta, which depend on informati ...20082397329
the medical reform group has a purpose. 20082390747
comment: doxorubicin extravasions. 20082596144
endoscopic suspension of the bladder neck by the stamey method for urinary incontinence.eighteen women with stress incontinence underwent endoscopic suspension of the bladder neck by the method of stamey. the procedure was carried out in a department of general surgery. pre- and postoperatively the patients were evaluated by pelvic examination with stress test, colpo-cysto-urethrography, urinary flow rate measurement, cystometry, and culture of the urine. fifteen became fully continent at once, another two after having been treated further by posterior colpoperineorraphy, while one ...20082628392
"o" ring coping attachment for a telescopic prosthodontic appliance. 20082700756
hypergammaglobulinemia and the anticardiolipin antibody test. 20082735967
dialabetic. 20082527708
neu receptor dimerization. 20082567498
antibodies to lymphoblastoid interferon. 20082570278
oral morphine for pain control in cancer patients. 20082441476
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