Publications

induction of reaginic (ige) gonococcal antibodies in the rat by a common antigen of neisseria gonorrhoeae.	an antigen (zab) common to neisseria gonorrhoeae was prepared by stepwise elution of a crude gonococcal antigen (za) from columns of diethylaminoethyl cellulose employing 0.02 m phosphate buffers, ph 7.6, containing increasing concentrations of sodium chloride. rats immunized with zab produced reaginic (ige) antibody which cross-reacted with za prepared from eight gonococcal strains by the passive cutaneous anaphylaxis (pca) test. heating of the sera at 56 degrees c for 4 h destroyed the pca act ...	1979	108009
[antiarrhythmic properties of 3-(2-hydroxy-3 isopropylamino-propoxy)-3 phenyl-2 isoindolinone-1, (rs, sr) in the dog].	in the dog, 3-(2-hydroxy-3 isopropylamino-proxy)-2-phenyl-1-isoindolinone (rs, sr) possesses an anti-arrhythmic activity similar to that of quinidine but at dose levels 2 to 6 times lower than in the case of the latter compound. furthermore, in contrast to quinidine, at the dose levels where the antiarrhythmic activity is well observed, the compound is devoid of hypotensive activity and of depressive action on cardiac contractility. the first clinical studies of this compound have shown its usef ...	1979	108025
the viability of cryopreserved aegyptianella pullorum carpano, 1928 in the vector argas (persicargas) walkerae kaiser and hoogstraal, 1969.		1979	107668
pituitary-thyroid function in spironolactone treated hypertensive women.	four weeks high dose spironolactone treatment (aldactone searle, 100 mg q. i. d.) significantly enhanced the tsh (delta max. 8.5 +/- 4.1 vs. 4.6 +/- 3.1 microunits/ml, p less than 0.05) and t3 (delta max. 32 +/- 27 vs. 11 +/- 16 ng/100 ml, p less than 0.05) responses to an intravenous trh/lh-rh bolus injection in 6 eumenorrhoeic euthyroid hypertensive women, without affecting basal serum tsh, t3 or t4 levels or the basal and stimulated lh, fsh and prolactin values (p greater than 0.10). the mean ...	1979	107696
adverse hemodynamic and ultrastructural changes in dog hearts subjected to protein-calorie malnutrition.	in the absence of thiamine deficiency, the specific effects of protein-calorie malnutrition on left ventricular (l.v.) function are unknown. mature beagle dogs of both sexes were subjected to a hypocaloric, nitrogen-poor diet which resulted in a weight loss of approximately 40% after seven weeks. following preparation of this nutritional model, myocardial contractility was assessed acutely by obtaining isovolumetric l.v. contractions on cardiopulmonary bypass at constant heart rate, mean aortic ...	1979	107775
pseudomonas orbital cellulitis.	a 3-month-old infant being treated for bronchitis developed a rapid onset but otherwise typical orbital cellulitis. because gram-negative infections and septicemia are common occurrences in the newborn nursery, this patient was given systemic gentamicin and ampicillin. sinus x-rays were not attempted. two days after treatment the eyelids were opened. a strikingly large corneal ulcer with perforated globe and endophthalmitis was found. pseudomonas aeroginosa was cultured from the blood, conjuncti ...	1979	107805
experimental transmission of wuchereria bancrofti to monkeys.	infective larvae of wuchereria bancrofti from laboratory-raised culex pipiens fatigans and aedes togoi mosquitoes fed on human volunteers in jakarta, indonesia (j strain) and kinmen island, china (k strain) were introduced into taiwan monkeys (macaca cyclopis) by subcutaneous inoculation, by foot puncture, or by permitting infected mosquitoes to feed weekly on the monkeys. some animals were splenectomized and others were treated with varying regimens of immunosuppressants. necropsy was done on m ...	1979	107818
glyconamides as inhibitors of human beta-glucosidases and beta-galactosidases.		1979	107857
[a patient with meningococcal pericarditis without signs of meningitis].		1979	107462
congenital partial hemimelia tibia in a kitten.		1979	106597
trans-stilbene oxide: a new inducer of rat liver microsomal udp-glucuronyltransferase.		1979	106858
carboxypeptidase of streptomyces griseus. implications of its characteristics.		1979	106886
a monolayer study of the reaction of trinitrobenzene sulphonic acid with amino phospholipids.	the reaction of trinitrobenzene sulphonic acid with amino phospholipids, and in particular phosphatidylethanolamine has been studied by the monolayer technique. injection of trinitrobenzene sulphonic acid under a monolayer of amino phospholipid results in an increase in surface pressure. the rate and extent of the pressure change is greatly affected by the initial surface pressure, the fatty acid composition of the lipid, and the presence of other non-reactive lipids, especially negatively charg ...	1979	106889
inhibition of neisseria gonorrhoeae by normal human saliva.	saliva was found to be a powerful and specific inhibitor of neisseria gonorrhoeae. although 28 other species of bacteria were tested, including neisseria meningitidis, neisseria pharyngis var flava, neisseria lactamica, and neisseria catarrhalis, we failed to find any others sensitive to saliva under similar conditions. the physical properties of the inhibitory substance indicated that it might be salivary alpha-amylase. to test this hypothesis alpha-amylase was extracted from saliva and was sho ...	1979	106919
[effects of chemotherapeutic agents on strains of neisseria meningitidis isolated in bohemia during 1970-1976].		1979	106970
effects of nitroglycerin on echocardiographic measurements of left ventricular wall thickness and regional myocardial performance during acute coronary ischemia.	the effects of nitroglycerin on regional left ventricular performance, assessed by echocardiographic techniques, were investigated in anesthetized, open-chest dogs during acute myocardial ischemia. during transient occlusion of the left anterior descending coronary artery, there was end-diastolic thinning and marked reduction in systolic thickening in the central ischemic zone. similar changes of lesser degree were noted in the border zone. the normal zone was unaffected. infusion of nitroglycer ...	1979	106986
liver transplantation.		1979	107000
contralateral projection of primary afferent fibers to mammalian spinal cord.		1979	107041
influence of alvogyl on the healing of extraction wound in man.	eight volunteer patients free of any systamic disease underwent extraction of two teeth on the same day. one extraction socket was packed with alvogyl, the other served as a control wound. biopsies for histological assessment were taken from both sockets 1 and 2 weeks after extraction. histological study revealed the normal sequence of wound healing in the sockets allowed to heal spontaneously. on the other hand, the signs of retarded wound healing (acute inflammatory infiltrate, persistent gran ...	1979	107131
rubella virus maturation and production in two host cell systems.	when inoculated at the same moi, vero cells released a larger amount of infectious rubella virus into the culture medium than did bhk21 cells, however, bhk21 cells (in monolayer or in suspension) produced more intracellular infectious virus than vero cells when tested 24 h after infection. maturation of the virus in bhk21 cells occurred at the plasma membrane and, in a larger quantity, in the cytoplasm (golgi apparatus and vacuoles). viral particles consisted of an electron-dense core (32 nm) su ...	1979	107143
overall pathway of mononucleosome production.	five electrophoretically distinguishable classes of mononucleosomes (mi, mii, ...mv) are produced upon treatment of mammalian nuclear chromatin with micrococcal nuclease. these five forms differ in their initial dna lengths, relative mass proportions, stability, contents of histone h1, and presence of certain nonhistone proteins. a new "chromatin fingerprinting" technique has been developed in order to trace nuclease-mediated interconversions between these mononucleosomes and their polynucleosom ...	1979	107168
acetylated methylmannose polysaccharide of streptomyces griseus. locations of the acetyl groups.	the positions of esterification of the 4 to 5 acetyl residues in the acetylated methylmannose-containing polysaccharide from streptomyces griseus have been established by the methyl replacement technique, wherein ester substituents are specifically replaced with methyl ether substituents. the newly incorporated methyl groups were distinguished from 3-o-methyl groups by the use of polysaccharide containing radioactively labeled endogenous methyl groups. the positions of methyl group localization ...	1979	107171
alcohol, malnutrition and liver disease.		1979	107268
dietary protein, aryl hydrocarbon hydroxylase and chemical carcinogenesis in rats.		1979	107295
percutaneous nitroglycerin absorption in rats.	percutaneous nitroglycerin absorption was studied in shaved rats by monitoring unchanged plasma drug concentrations for up to 4 hr. drug absorption from the neat liquid state or from an alcoholic solution was considerably poorer than that from a commercial ointment. this observation was unanticipated since the driving force for percutaneous drug absorption was assumed to be drug thermodynamics. potential artifacts such as drug volatilization from the skin, reduction of surface area through dropl ...	1979	107313
the antinociceptive effect of intracerebroventricularly administered prostaglandin e1 in the rat.	it is generally accepted that prostaglandins (pgs) are nociceptive substances. however, earlier studies from this laboratory indicated that morphine analgesia, in the rat, was not only serotonin mediated, but involved pgs as well. several pg synthesis inhibitors were shown to inhibit morphine analgesia and pge1 was shown to potentiate the antinociceptive effect of morphine. intraperitoneal administration of pge1, but not pge2 and pgf2alpha, elicited antinociceptive effect per se, by the radiant ...	1979	106425
effects of atenolol and propranolol on human performance and subjective feelings.	in a double-blind, double crossover experiment, 18 healthy young men received over 3-day periods either 100 mg atenolol, 80 mg propranolol, or placebo. the subjects underwent various motor and cognitive tests 18 h after each last dose had been taken. propranolol significantly increased variability of a choice reaction-time task. scores on various subjective rating scales showed that propranolol had a larger mood elevating effect than atenolol. heart rate and blood pressure were significantly red ...	1979	106432
[isolation and general characteristics of a group of pseudomonas aeruginosa temperate phages].	eighteen temperate phages were isolated from 38 natural strains of pseudomonas aeruginosa. the phages belong to five heteroimmune groups according to the ability of lysogenic variants of the strains pao1 and pat2 to exclude the growth of the superinfecting phage. phages of the ii and v immunity groups are serologically similar; the remaining phages are not inactivated by antisera against phages b26 (ii group) and k1338 (v group). prophages of the ii, iv, and v groups are induced by uv for vegeta ...	1979	106221
[xerophytic microorganisms multiplying under conditions close to martian ones].	the xerophytic cultures bacillus megaterium and mycococcus ruber can grow in the imitated martian conditions. therefore, they are resistant to the extreme factors of the environment: the composition of atmosphere, low pressure, the maximum hygroscopicity of a substrate, periodic freezing-thawing.	1979	106224
maternal separation vs removal from group companions in rhesus monkeys.		1979	106065
comparative in vivo nitrogen-15 nuclear magnetic resonance study of the cell wall components of five gram-positive bacteria.	the proton-decoupled 9.12 mhz 15n nmr spectra of 15n-labeled bacillus subtilis, bacillus licheniformis, staphylococcus auresu, streptococcus faecalis, and micrococcus lysodeikticus intact cells, isolated cells walls, and cell wall digests have been examined. the general characteristics of gram-positive bacteria 15n nmr spectra and described and spectral assignments are provided, which allow in vivo 15n nmr to be applied to a wide range of problems in bacterial cell wall research. the qualitative ...	1979	105756
[determination of cholera vibrion enterotoxin by an aggregate hemagglutination method].		1979	105503
characterization of plasmid transformation in bacillus subtilis: kinetic properties and the effect of dna conformation.	transformation of competent cells of bacillus subtilis with antibiotic resistance plasmid dna has shown that (a) competence for plasmid and chromosomal dna develops with similar kinetics; (b) dna linearized with a variety of restriction endonucleases does not transform; (c) ccc plasmid dna is inactivated for transformation by a single nick; (d) t4 ligase restores transforming activity to both nicked and linearized dna; (e) ccc relaxed dna is fully active in transformation; (f) the dna concentrat ...	1979	105246
field trials of slow-release formulations of chlorpyrifos and malathion for the control of chagas's disease vectors.		1979	95561
restricted posterior parietal lesions in the rhesus monkey and performance on visuospatial tasks.	monkeys with lesions restricted to the inferior parietal lobule or the banks and depths of the superior temporal sulcus were tested on a route-following task. these areas are considered on neuroanatomical grounds to be homologous to parts of the human posterior parietal cortex, where lesions produce profound spatial disorientation. the operated monkeys were impaired on the route task, thus confirming at the behavioural level the anatomical predictions of comparability between parietal cortex in ...	1979	103604
effects of immunization with the beta-subunit of ovine luteinizing hormone on corpus luteum function in the rhesus monkey.	rhesus monkeys immunized with the beta-subunit of ovine luteinizing hormone (olhbeta) developed circulating antibodies which cross-reacted strongly with rhesus monkey chorionic gonadotropin. normal ovulatory cycles continued, but the fertility of immunized monkeys as compared with that of controls was significantly reduced. thus, the rhesus monkey represented a useful animal model for the study of certain aspects of an "antifertility vaccine." we investigated the effects of circulating antibodie ...	1979	104890
[study of the initial stages of microorganism growth and development for assessing the bactericidal action of chemical substances].		1979	104902
transcription and translation in a pleiotropic streptomycin-resistant mutant of escherichia coli.	the role of the ribosomal protein s12 (streptomycin protein) in ribosome function and in other metabolic processes in the cell has been investigated. a spontaneous streptomycin-resistant strain of escherichia coli (sm3) carrying a mutation in the rpsl gene is deficient in its ability to induce the synthesis of the enzyme bets-galactosidase. it was demonstrated that the reduced rate of enzyme synthesis results from deficiencies in both the transcription of the lactose operon and translation of th ...	1979	104958
separation and characterization of highly purified forms of liver microsomal cytochrome p-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.		1979	105007
turnover of human and monkey plasma kininogens in rhesus monkeys.	the normal metabolic turnover of plasma kininogens was studied by measuring the disappearance of intravenously administered radiolabeled human and monkey plasma kininogens from the circulation of healthy adult rhesus monkeys. curves obtained by plotting log radioactivity against time could be expressed as double exponential equations, with the first term representing diffusion, and the second, catabolism. no significant difference between the turnovers of human and monkey kininogens was observed ...	1979	105015
implications for adult roles from differential styles of mother-infant bonding: an ethological study.	ethological observations of maternal and infant behaviors of nine vervet monkey pairs (cercopithecus aethiops sabaeus) showed the effects of differential styles of early maternal responsiveness on later infant competence. those infants receiving the least amount of maternal responsiveness and the most time-off the mother in the first 3 months of development were more socially competent at 6 months of age. the results are discussed within current ethological "attachment" theories. the detachment ...	1979	105083
the pathophysiology of asthma.	because postmortem studies of humans provide little information on the initial pathophysiologic events in asthma, animal models have been developed. recently the ascaris-allergic rhesus monkey has provided an opportunity to examine the onset of pathophysiologic changes following challenge and to correlate them with airway structure. these studies have suggested that the initial interaction between antigen and mast cells may occur in the bronchial lumen or in the epithelium superficial to the tig ...	1979	89006
trasylol prevents trypsin-induced shock in dogs.	the effect of simultaneous intravenous administration in the dog of bovine trypsin and trasylol followed by continued infusion of trasylol was studied. special attention was paid to the interchange between the dominating plasma protease inhibitors alpha1-antitrypsin and a-macroglobulins and to the disappearance of trasylol and its trypsin complexes from the circulation. the following results were obtained: 1) trypsin was preferentially bound by the alpha-macroglobulins, though trasylol is a stro ...	1979	89067
steroid secretion by in vitro perfused testes: inhibitors of testosterone biosynthesis.		1979	89816
[application to the study of connections in the cns of the retrograde axonal transport of an iron-dextran complex].	the retrograde axonal transport of an iron-dextran complex was observed in neurons of the substantia nigra and of the intralaminar nuclei of the thalamus, after previous injection into the striatum. the histochemical demonstration of iron is simple and rapid, and can be combined with that of horseradish peroxidase, under precise conditions in the sequence of reactions. the iron-dextran complex revealed to be a valuable material for neuronal connectivity studies in the central nervous system.	1979	89914
antigenic drift in type a influenza virus: sequence differences in the hemagglutinin of hong kong (h3n2) variants selected with monoclonal hybridoma antibodies.		1979	90425
location of the antigenic determinants of bovine pancreatic ribonuclease.	four antigenic regions of native bovine pancreatic ribonuclease have been located by using antibodies that react specifically with segments 1--13, 31--79, and 80--124. these antibodies were purified by affinity chromatography on columns to which these peptide segments were bound. analysis of precipitin curves indicates that there are at least three antigenic determinants to which antibody molecules can bind simultaneously in the presence of excess antibodies. analysis of binding data, however, f ...	1979	90520
relative affinity of antisera for myelin basic protein (mbp) and degree of affinity heterogeneity.		1979	90641
characterization of the antigenic determinants of cholera toxin subunits.	the antigenic specificity of purified preparations of a subunit, b subunit, alpha chain, and gamma chain of cholera toxin was studied by double immunodiffusion and radioimmunoassay with antisera produced in rabbits and mice. rabbits immunized with a subunit produced serum antibodies which were capable of binding radiolabeled a subunit, alpha chain, and b subunit. rabbits immunized with alpha chain produced serum antibodies that would bind radiolabeled alpha chain and a subunit. rabbits immunized ...	1979	90654
the genetics of an expanded secretor system.	the genetics of salivary secretion of abh blood group substance was investigated. eight secretor phenotypes were determined by sephadex g-100 chromatography. presence or absence of three different fractions were shown to be controlled by three different secretor gene loci. these loci are called sec1, sec2 and sec3. sec1 controls expression of the traditional secretor status. sec2 and sec3 are linked, but distinct, loci controlling the expression of low molecular weight abh substance in human sal ...	1979	90711
rubella vaccines.		1979	90773
bottle feeding as a risk factor for cholera in infants.	to determine risk factors for cholera in infants, a retrospective matched-pair study of 42 cases and their controls was undertaken during an outbreak of el tor cholera in bahrain in the autumn of 1978. the highest attack-rate of cholera (125/10 000) occurred in infants in the 6--11 month age-group, which corresponds to the weaning age in this community. significantly more cases than controls were principally bottle fed (greater than 50% milk intake by bottle) than principally breast fed during t ...	1979	90813
antimicrobial susceptibility of vibrio cholerae from zaire and rwanda.		1979	90940
viral liver disease.		1979	91032
the structure and evolution of the hla--bw4 and bw6 antigens.	the hla--bw4 and bw6 antigenic determinants have been shown to co-migrate with hla--b determinants on gel-filtration, sucrose density gradient centrifugation and affinity chromatography, using lens culinaris lectin and antibody against human beta 2 microbulin. these and other published data imply that the hla--bw4 and bw6 determinants reside on the same polypeptide chain as other hla--b locus determinants. the implications of this in terms of the evolution of cross reacting groups of antigens at ...	1979	91209
[use of antistaphylococcal immune preparations in acute suppurative-septic staphylococcal diseases].		1979	91270
latex fetuin spheres as probes for influenza virus neuraminidase in productively and abortively infected cells.	fetuin bound latex spheres do not adhere to the membranes of non-infected cells but adhere to those of cells productively infected by fowl plague virus (fpv dobson strain). in contrast, asialo fetuin spheres do not attach to the membranes of productively infected cells. moreover latex fetuin spheres incubated with extracts of productively infected cells and extensively washed are specifically enriched in neuraminidase activity without any trace of haemagglutinin. these observations suggest that ...	1979	91354
ultrastructure of peripheral nerves of mice inoculated with rabies virus.	fourty adult female albino mice were inoculated in the right hind leg with rabies viruses of the street type. the mice were sacrificed with an interval of 24 hours each, starting in the next day after inoculation. from the 10th day ownwards the animals started presenting signs of paralysis, first on the leg where the viruses were inoculated anbnormalities were found in peripheral nerves compatible with axonal degeneration with secondary demyelination but the rabies viruses were not found in the ...	1979	91359
[anti-arrhythmic effect of tetrodotoxin in the late stage of experimental myocardial infarct].	the action of tetrodotoxin (tt), blocking the fast sodium current, on arrhythmias that occurred 24 hours after occlusion of the coronary artery was studied in 10 dogs. tt injected intravenously in doses of 0.5--3.0 micrograms/kg significantly decreased the number of ventricular extrasystoles, and completely restored sinum rhythm in 4 animals. the maximum antiarrhythmic effect was noted 3 to 5 minutes after tt adminstration. it is suggested that arrhythmias and the antiarrhythmic effect of the dr ...	1979	91393
connectivity of the auditory forebrain nuclei in the guinea fowl (numida meleagris).	injection of tritiated leucine and proline into the nucleus ovoidalis of the guinea fowl (numida meleagris) produces terminal labeling in the palaeostriatum and in three adjacent zones (field l1-l3) of the auditory neostriatum (an). l2, situated between l1 and l3, receives the main input and corresponds to the former field l of rose. these neuroanatomically defined zones of the auditory neostriatum are also characterized by differing properties of their neurons. injection of radioactive material ...	1979	91442
short latency mechanically evoked somatosensory potentials in humans.	somatosensory potentials evoked by mechanical stimulation were recorded by surface electrodes over (1) the digital nerves in the index finger, (2) the median nerve at the wrist, (3) the median nerve near the axilla, (4) the brachial plexus, (5) the cervical cord at cii, (6) the scalp overlying the somatosensory cortex. nerve conduction velocities varied inversely with age and ranged from 43 to 68 m/sec. mechanically evoked potentials recorded from the electrodes overlying the digital nerves were ...	1979	91479
procaine-induced seizures in epileptic monkeys with bilateral hippocampal foci.	intravenous procaine hcl given at low doses (0.5-2.5 mg/kg) to two monkeys with bilateral alumina hippocampal foci depressed interictal spiking or had little effect. at 5.0 mg/kg unilateral limbic activation occurred. at 10.0 mg/kg unilateral or bilateral limbic activation and generalized seizures could be evoked within 3-10 min. at higher doses (15 and 20 mg/kg) bilateral limbic activation or brief (one min) generalized seizures occurred. the unilateral-onset psychomotor seizures were not ident ...	1979	91502
antigenic correlation between rat brain synaptic vesicles and rat bone marrow b lymphocytes.	rabbit anti-rat brain synaptic vesicle serum reacted with thymocytes and b lymphocytes in cytotoxicity and immunofluorescence assays. quantitative absorption analysis revealed that this antiserum contained antibodies specific for antigenic determinants on the surface membrane of a subpopulation of rat bone marrow b lymphocytes.	1979	91533
generation of a fibroblast chemotactic factor in serum by activation of complement.	when serum complement is activated by either the classical or alternative pathways, a factor with an apparent 80,000 mol wt is generated that is chemotactic for human dermal fibroblasts. the origin of this serum-derived chemotactic factor (sdcf) is not known; however, it may be a cleavage product from c5 because it is inactivated by monospecific antiserum to human c5, and it is not generated when the complement system is activated in human serum deficient in c5. sdcf is not chemotactic for human ...	1979	91624
human lung tumor-associated antigens of 32,000 daltons molecular weight.	lung tumor-associated antigens of approximately 32,000 daltons were recognized by the use of sensitive radioimmunoassays and rabbit antisera, one raised against an extract of pooled human malignant lung tissues and another raised against a cell line derived from a human squamous cell carcinoma of the lung. these antigens differ from antigens described previously, including carcinoembryonic antigen and alpha-fetoprotein. the antigens were detected on 13 of 13 lung tumors (of all histologic types) ...	1979	91695
[microscopic, immunochemical and ultrastructral study of livers histologically normal or subnormal in patients with hepatitis b surface antigen (hbs). report of 18 cases (author's transl)].	liver specimens obtained by biopsy in 18 patients with asymptomatic hbs ag were studied with specific immunofluorescent technic for this antigen by light and electron microscopy. only insignificant changes were disclosed by routine microscopy examination. under light microscopy "ground glass" hepatocytes were found in eight cases. specific immunofluorescence was found positive in nine cases and was closely correlated with the "ground glass" hepatocytes in eight of them. in one on the three cases ...	1979	92003
concanavalin a stimulates phospholipid methylation and phosphatidylserine decarboxylation in rat mast cells.	when histamine release from rat peritoneal mast cells is stimulated by concanavalin a, membrane phospholipids are methylated in the early stage of this process. exogenously added phosphatidylserine enhances the concanavalin a-induced histamine release, and at the same time the lectin markedly stimulates the decarboxylation and methylation of phosphatidylserine. within minutes after the addition of concanavalin a to rat mast cells, the newly methylated phospholipids begin to disappear and an incr ...	1979	92021
micromplement fixation studies of human plasma prothrombin and purified prothrombin preparations.		1979	92071
[cutaneous leishmaniasis. alcoy: an endemic zone].		1979	92178
horizontal organization of velocity characteristics in area 18 of the cat [proceedings].		1979	92238
effect of fat structure on total, on chylomicron, and on high-density lipoprotein cholesterol in the absorptive state in man [proceedings].		1979	92248
triiodothyronine (t3) receptors in brain and liver during induced hypothyroidism in rats [proceedings].		1979	92254
fate of a "maturation-specific" messenger rna during early germination of mung-bean seeds [proceedings].		1979	92270
[experimental use of prostaglandin f2 alpha to synchronize estrus in cattle].	experiments were conducted for the use of prostaglandin to synchronise oestrus in dairy cows. one single dose of 5 mg f2-alpha prostaglandin was administered via the intrauterine route. the reference values of the control groups were matched by first insemination following induced oestrus among the best of the test animals which were inseminated twice. these values reached 72 and 96 hours following application accounted for 46.7 and 50.0 per cent. the yellow body phase, a prerequisite for oestru ...	1979	92295
immunological cross-reactivity between acid extracts of myelin, liver and neoplastic tissues: studies in immunized guinea-pigs.	groups of 4 guinea-pigs were immunized with acid extracts prepared from bovine myelin (ef), normal human liver tissue and malignant or benign neoplastic tissues in freund's complete adjuvant (fca1. the animals were weighed daily and examined for clinical signs of experimental allergic encephalomyelitis (eae). all the animals immunized with ef developed clinical symptoms of eae within 21 days of the initial immunization, whilst some of the animals immunized with certain tumour extracts developed ...	1979	92328
suramin: a potent inhibitor of the reverse transcriptase of rna tumor viruses.	suramin--a well-known antitrypanosomal agent--was found to exert a strong inhibitory effect on the rna-directed dna polymerase (reverse transcriptase) activity of several oncornaviruses such as moloney murine leukemia virus, murine rauscher leukemia viruses, moloney murine sarcoma virus and avian myeloblastosis virus. inhibition of enzyme activity was obtained with both endogenous viral rna and (a)n . oligo(dt) as the template-primer. suramin effected a 50% inhibition of the reverse transcriptas ...	1979	92362
histochemical observations on pneumocystis carinii: selective demonstration of honeycomb forms.	histochemical investigations of pulmonary lesions indicated selective coloration of membranes of honeycomb stages of pneumocystis carinii by the periodic acid--sodium bisulfite--resorcin-fuchsin reaction for basement membranes; mucus, fibrin and other deposits in respiratory pathways did not react. these membranes were colored selectively also by the picro-sirius red f3ba method for collagens; fungi in tissues from patients with candidiasis remained unstained. for simultaneous demonstration of h ...	1979	92466
nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry.	nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ...	1979	92496
immunoelectron microscopic localization of herpes simplex virus antigens in infected cells using the unlabeled antibody-enzyme method.	subcellular localization of viral antigens was demonstrated during viral morphogenesis using herpes simplex virus type 1 (hsv-1) infected monolayers of rabbit cornea cells. the localization was done by immunoelectron microscopy employing the peroxidase-antiperoxidase (pap) immunocytochemical technique and the postembedding staining method. the localization of viral antigens was followed at time intervals during infection from 2 to 19 hr. after exposure of sections to either polyspecific antibodi ...	1979	92500
evaluation of the validity of the histochemical lead nitrate technique for alkaline and acid deoxyribonuclease.	the results of several tests and the characteristic morphological distribution of the enzymatic activity appeared to be in favor of the validity and specificity of the histochemical lead nitrate technique for alkaline and acid deoxyribonuclease (dnase) detection. these tests included thermal inhibition, omission of substrate, use of different chemical inhibitors and the reproduction of histochemical staining on coujard's slides. most of these results were in conformity with the biochemical data ...	1979	92502
macrophage oxygen-dependent antimicrobial activity. i. susceptibility of toxoplasma gondii to oxygen intermediates.	a sensitive method for evaluating extracellular parasite viability was used to determine the in vitro susceptibility of virulent toxoplasma gondii to selected oxygen intermediates. by acridine orange fluorescent staining criteria, toxoplasmas were resistant to up to either 10(-3) m reagent h2o2 or h2o2 generated by glucose-glucose oxidase. in keeping with a lack of sensitivity to h2o2, toxoplasmas contained endogenous catalase (5.7 x 10(-4) baudhuin units/10(6) organisms). the addition of a pero ...	1979	92521
ia determinants on human t-cell subsets defined by monoclonal antibody. activation stimuli required for expression.	the nature of ia antigens which appear on human t cells after activation and the stimuli required for their expression was examined utilizing a monoclonal antibody reactive with the ia antigen framework. t cells were purified using monoclonal antibodies directed either at the entire t-cell population (okt3) or the t-cell inducer subset (okt4). by indirect immunofluorescence, it was shown that the human t-cell population contains no detectable ia+ cells in the resting state. in contrast, in exces ...	1979	92523
correlation between the capacity of bacterial lipopolysaccharide to supress experimental allergic encephalomyelitis and its mitogenic activity for lymph node cells in guinea pigs.	protection of guinea pigs from experimental allergic encephalomyelitis (eae) was attempted using bacterial lipopolysaccharide (lps) from 4 sources. the ability of these lps to induce dna synthesis in guinea pig lymph node (ln) cells in vitro was also investigated. it was found that there existed a good correlation between the capacity of lps to suppress eae and their degree of mitogenic activities for ln cells. lps from escherichia coli 0111:b4 (ec-lps), which was most effective in suppressing e ...	1979	92530
biologically active polycycloalkanes. 6. antiviral 1-tricyclo[4.3.1.1 2,5]undecyl derivatives.	functionalization reactions via cationic intermediates of tricyclo[4.3.1.1 2,5]undecane (2) were investigated to prepare derivatives with potential antiviral activities. bromination of 2 took place regiospecifically at c-1, and the resulted bromide 5 was converted into the hydroxide 9, the carboxylic acid 12, and the amine 22, from which were synthesized a variety of secondary derivatives, including homologous esters 10 and 20, amides 14 and 19, carbamates 24, and ureas 17 and 25. the hydroxide ...	1979	92566
the accessibility of antigenic determinants of ribosomal protein s4 in situ.	antibodies to escherichia coli ribosomal protein s4 react with s4 in subribosomal particles, eg, the complex of 16s rna with s4, s7, s8, s15, s16, s17, and s19 and the ri reconstitution intermediate, but they do not react with intact 30s subunits. antibodies were isolated by three different methods from antisera obtained during the immunization of eight rabbits. some of these antibody preparations, which contained contaminant antibodies directed against other ribosomal proteins, reacted with sub ...	1979	92615
ultrastructure and partial characterization of a regular array in the cell wall of lactobacillus brevis.	the cell wall of lactobacillus brevis was revealed by electron microscopy to have an outer layer composed of a regular array. the morphological unit of the regular array appeared to consist of four spherical subunits, each about 2 nm in diameter, which were arranged in a tetragonal pattern about 4.5 by 7.0 nm in dimension. the regular array was composed of the tetragonal units in rows in two directions at an angle of about 75 degrees to each other. the average spacing between the rows was about ...	1979	92747
olivocerebellar projections in the cat studied by means of anterograde axonal transport of labelled amino acids as tracers.		1979	92769
the zinc iodide-osmium (zio) reaction in the central nervous system: localization and relations to functional activity.	the fine structural characteristics of zio reaction was studied in the cerebral and cerebellar cortex and olfactory bulb of the rat and in synaptosomes prepared from rat cerebellar cortex. it was concluded that: 1. organelles of different nerve cell types exhibit different zio reactions provided that the impregnation was carried out under standardized conditions. 2. 6...10 times more synaptic vesicles were stained by zio in the inhibitory terminals than in the excitatory ones. 3. zio positivity ...	1979	92863
alpha-feto-protein (afp) and human chorionic gonadotropin (hcg) as biochemical markers of intracranial germ-cell tumours.		1979	92878
prostate-specific acid phosphatase: purification and specific antibody production in rabbits.	demonstration of prostate-specific acid phosphatase by immunologic methods in tissue sections or in plasma necessitates a monospecific antiserum. this is produced by immunizing rabbits with pure prostate-specific acid phosphatase antigen, prepared from seminal fluid. the ejaculate is centrifuged, dialyzed against a citrate buffer, ph 4.8, and centrifuged again. the supernatant is brought onto a sephacryl s-200 superfine column and eluted with the same buffer. prostate-specific acid phosphatase-p ...	1979	92890
[relations between oxoglutarate transport function and variations of space in rat heart mitochondria (proceedings)].		1979	92958
antigenic similarity of morphologic type ciii1 bacteriophages.	the aim of the study was to demonstrate antigenic differentiation among bacteriophages belonging to the same morphologic type--ciii1 according to krzywy and slopek or a2 according to ackermann. twenty-six bacteriophages which multiplied on various strains of bacteria of the genera escherichia, shigella and klebsiella, were studied. serologic tests were done by the quantitative complement fixation test. immune sera against 5 phi e. coli. d8 sh. flexneri, g35 sh. sonnei and kl7 klebsiella bacterio ...	1979	92976
[two-layer rocket-electrophoresis on cellulose-acetate membranes].	two-floor rocket-electrophoresis on gelatinated acetate cellulose membrane "cellogel" has been developed. the method is based on electroimmunodiffusion detection of the antigen on the acetate-cellulose membranes, containing monospecific antiserum of the test-system. the procedure is followed by the detection of precipitation bands ("rockets") by staining, if the reaction is conducted in the visible zone or by the further treatment of the acetate-cellulose strips, containing invisible precipitate ...	1979	93004
[immunosuppression in rabbits using the serum of splenectomized animals (author's transl)].		1979	93023
the effect of dose loading and of double labelling with 57co and 125i on the tissue distribution in animals.	dose loading effects upon the performance of 57co-bleomycin as a tumor localizing agent have been investigated in rhabdomyosarcoma bearing wag/ry rats. the addition of non-radioactively labelled co-bleomycin increased the relative uptake of 57co-bleomycin in rapid growing tumors, but the addition of non-chelated bleomycin had no influence at all. in our experimental system, iodinated bleomycin generally labelled by reaction with icl, was found to be an unsatisfactory tumor localizing agent. in o ...	1979	93048
[hygienic standards for a mixture of hexachlorane and phosalone in the atmosphere].		1979	93066
histochemical reactions of gastrointestinal mucosubstances with high iron diamine after prior oxidation and methylation of tissue sections.	high iron diamine reactions after the prior methylation and oxidation of tissue sections with performic acid or potassium permanganate (metox-hid or ox-met-hid) in epithelial mucosubstances and in mucosal mast cells were studied in tissue samples from the human gastrointestinal tract and were compared with reactions with high iron diamine without any pretreatment (hid) and high iron diamine with the prior methylation (met-hid). high iron diamine reactions after the prior oxidation (met-ox-hid, o ...	1979	93103
analysis of vibrio parahaemolyticus soluble antigens by employing passive hemagglutination.	the passive hemagglutination assay was explored as a sensitive test of immunological reactivity of endotoxin and other antigens prepared from selected strains of vibrio parahaemolyticus. the tannic acid procedure for passive hemagglutination, commonly used with protein antigens, was the only procedure yielding good results with v. parahaemolyticus protein extracts, endotoxins, and related preparations. these results were probably due to the presence of large amounts of protein in the v. parahaem ...	1979	93111
experimental infection with ancylostoma caninum larvae in mice. vi. serum protein pattern use due to repeated exposures to infection.	three mice groups were infected with various repeated doses and other four groups with single doses of ancylostoma caninum larvae. serum samples collected at various intervals were analysed electrophoretically. the results were compared first with an uninfected control group and then with those of the corresponding non-immunized single-dose-infected groups. remarkably decreased values of albumin, increased beta globulin and increased total globulins with a decreased a/g ratio were observed. ther ...	1979	93128
induction of ecotropic endogenous murine leukemia virus in long-term bone marrow cultures from mouse strains of varying natural leukemia incidence.		1979	93145