Publications

the genetic identification of camel contagious ecthyma virus as the causative agent of contagious ecthyma in dromedary camels (camelus dromedarius) in qatar.	camel contagious ecthyma is a contagious viral disease of camels caused by either orf virus (orfv) or camel contagious ecthyma virus (ccev). it has been previously reported and shown to cause economic losses in some camel-rearing countries in asia and africa, but has not been detected in qatar. the purpose of this study was to identify and genetically characterize the contagious ecthyma causative agent in qatari dromedary camels between 2017 and 2018. accordingly, we made diagnoses of camel cont ...	2021	34008092
pathological and molecular investigations of systemic form of camelpox in naturally infected adult male dromedary camels in india.	camelpox is a wide-spread infectious viral disease of camelids. an outbreak of camelpox was reported in 15 adult male dromedary camels aged between 10 to 16 years of an organized herd in winter season. the infected camels showed clinical signs of fever, anorexia, lachrymation, pendulous lips, excessive salivation and pock lesions on the skin of head, neck, mouth, lips, extremities, thigh, abdomen, scrotum and inguinal region. mortalities were recorded in three infected camels after 10-12 days of ...	2021	33598582
a survey of bluetongue infection and associated risk factors among the one-humped camel (camelus dromedaries) in gadarif state, eastern sudan.	bluetongue (bt) is an infectious, noncontagious, vector-borne viral disease that affects wild and domestic ruminants transmitted by culicoides spp. a cross-sectional study was carried out during the period 2016-2017 in gadarif state. a total of 276 sera samples were collected from camels in six localities of gadarif state, eastern sudan, to investigate bluetongue virus (btv) seroprevalence and associated risk factors of btv infection including age, sex, breed, locality, and ecology of the region ...	2021	33833864
sero-epidemiological survey of bluetongue disease in one-humped camel (camelus dromedarius) in kassala state, eastern sudan.	bluetongue (bt) is a vector-borne viral disease of ruminant and camelid species which is transmitted by culicoides spp. the causative agent of bt is bluetongue virus (btv) that belongs to genus orbivirus of the family reoviridae. the clinical disease is seen mainly in sheep but mostly sub-clinical infections of bt are seen in cattle, goats and camelids. the clinical reaction of camels to infection is usually not apparent. the disease is notifiable to the world organization for animal health (oie ...	2021	33771226
seroprevalence of bovine viral diarrhea virus in local borana cattle breed and camels (camelus dromedarius) in ethiopia.	bovine viral diarrhea, caused by bovine viral diarrhea virus (bvdv), has been considered a disease of cattle but is now emerging in camels. in ethiopia it has been detected in exotic and cross-bred dairy cattle but no information is available on its occurrence in indigenous cattle breeds and camels. this study was, therefore, conducted to estimate the prevalence of bvdv infection in indigenous borana cattle and camels (camelus dromedarius) in moyale and miesso pastoral districts.	2021	34136370
structural analysis of covid-19 spike protein in recognizing the ace2 receptor of different mammalian species and its susceptibility to viral infection.	the pandemic covid-19 was caused by a novel coronavirus-2 (sars-cov-2) that infects humans through the binding of glycosylated sars-cov-2 spike 2 protein to the glycosylated ace2 receptor. the spike 2 protein recognizes the n-terminal helices of the glycosylated metalloprotease domain in the human ace2 receptor. to understand the susceptibility of animals for infection and transmission, we did sequence and structure-based molecular interaction analysis of 16 ace2 receptors from different mammali ...	2021	33552834
nanobodies from camelid mice and llamas neutralize sars-cov-2 variants.	since the start of the covid-19 pandemic, sars-cov-2 has caused millions of deaths worldwide. although a number of vaccines have been deployed, the continual evolution of the receptor-binding domain (rbd) of the virus has challenged their efficacy. in particular, the emerging variants b.1.1.7, b.1.351 and p.1 (first detected in the uk, south africa and brazil, respectively) have compromised the efficacy of sera from patients who have recovered from covid-19 and immunotherapies that have received ...	2021	34098567
nonlinear dynamics for the spread of pathogenesis of covid-19 pandemic.	coronaviruses did not invite attention at a global level and responsiveness until the series of 2003-sars contagion followed by year-2012 mers plus, most recently, 2019-ncov eruptions. sars-cov &mers-cov are painstaking, extremely pathogenic. also, very evidently, both have been communicated from bats to palm-civets & dromedary camels and further transferred ultimately to humans. no country has been deprived of this viral genomic contamination wherever populaces reside and are interconnected. th ...	2021	34118731
which species does the virus like most: binding modes study between sars-cov-2 s protein and ace2 receptor.	the emergence of a novel coronavirus (sars-cov-2) has been spreading worldwide in 2020. coronaviruses could mainly cause respiratory tract infections in humans and multiple system infections in many animals. the coronavirus enters the host cell through the binding of surface spike glycoprotein (s protein) with host angiotensin-converting enzyme-ⅱ (ace2) protein.	2021	33740562
coronaviruses in humans and animals: the role of bats in viral evolution.	bats act as a natural reservoir for many viruses, including coronaviruses, and have played a crucial epidemiological role in the emergence of many viral diseases. coronaviruses have been known for 60 years. they are usually responsible for the induction of mild respiratory signs in humans. however, since 2002, the bat-borne virus started to induce fatal epidemics according to who reports. in this year, the first serious human coronavirus epidemic (severe acute respiratory syndrome; sars) occurre ...	2021	33655480
bovine coronavirus and the associated diseases.	coronaviruses (covs) possess the largest and most complex rna genome (up to 32 kb) that encodes for 16 non-structural proteins regulating rna synthesis and modification. coronaviruses are known to infect a wide range of mammalian and avian species causing remarkably diverse disease syndromes. variable tissue tropism and the ability to easily cross interspecies barriers are the well-known characteristics of certain covs. the 21st century epidemics of severe acute respiratory cov (sars-cov), middl ...	2021	33869323