Publications

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effect of terpenes on the cell permeability to tetracycline. 19724629176
antimicrobial properties of fungal macrolide antibiotics. 19724629229
[properties of mutants of bacillus subtilis which are resistant to the isoleucine antagonist ketomycin]. 19724629239
molecular basis for the differential anti-metabolite action of d-tyrosine in strains 23 and 168 of bacillus subtilis. 19724629377
inhibition of bacterial dna replication in vitro by 6-(p-hydroxyphenylazo)-uracil: selective interference with the function of deoxyguanosine nucleotides. 19724629423
the influence of secondary structure on the translation of ribosomal rna. 19724629470
carcinogen-induced trna methylase activity in yeast cells. 19724629471
characterization of an intracellular protease in b. subtillus during sporulation. 19724629621
purification of mycobacterial deoxyribonucleic acid.impurities believed to be polysaccharides have been found in mycobacterial deoxyribonucleic acid (dna) preparations. agar-gel diffusion of the dna preparations against concanavalin a indicated the presence of three polysaccharides and was used to follow the purification procedures. the polysaccharides appeared to be the same for all strains studied. precipitation of dna with cetyltrimethylammonium bromide was used to separate impurities from some dna preparations. the presence of the contaminant ...19724629650
action of phospholipase a 2 and phospholipase c on bacillus subtilis protoplasts.protoplasts prepared from bacillus subtilis by lysozyme digestion lysed in the presence of pure pancreatic phospholipase a(2). the phospholipids cardiolipin, phosphatidylethanolamine, phosphatidylglycerol and lysylphosphatidylglycerol, which are present in the membrane, are degraded by phospholipase a(2) only after removal of the cell wall, giving free fatty acids and lyso derivatives. the four phospholipids are hydrolyzed equally well at a given enzyme concentration. differences in the phosphol ...19724629652
template specificity of ribonucleic acid polymerase in asporogenous mutants of bacillus subtilis.asporogenous mutants of bacillus subtilis were examined for the change in template specificity of ribonucleic acid (rna) polymerase characteristic of wild-type cells undergoing sporulation. mutants blocked at stages ii, iii, and iv showed a changed specificity of the enzyme after the end of growth and were in this respect indistinguishable from the wild type. the rna polymerase of eight stage-zero mutants (out of nine tested) which possess mutations that map at six distinct loci retained the tem ...19724629655
teichoic acid hydrolase activity in soil bacteria (bacillus subtilis-sporulation-phosphodiesterase-polyamines-concanavalin a).bacterial phosphodiesterases have been found that are capable of cleaving the backbone of teichoic acid. such enzymes have not been reported previously. an aerobic, gram-negative, rod-shaped bacterium producing this activity was detected and isolated by autoradiography of soil suspensions growing on minimal medium containing (32)p-labeled bacillus subtilis atcc 6051 cell walls as the sole phosphorus source. broken-cell preparations are capable of depolymerizing teichoic acids in media of low ion ...19724333041
interaction of antibiotics with membranes: chlorothricin. 19724334682
action of haemophilus endodeoxyribonuclease on biologically active deoxyribonucleic acid.an enzyme similar to that described by smith and wilcox (15) for haemophilus influenzae which attacks foreign deoxyribonucleic acid (dna) but not its own has been isolated and purified from h. parainfluenzae. the enzyme degrades foreign dna to limited sizes and can destroy the transforming activity of h. influenzae and bacillus subtilis dna. the enzyme can also destroy the biological activity of h. influenzae phage and prophage dna. on the other hand, the h. influenzae endodeoxyribonuclease can ...19724334766
isolation of a lysine transfer ribonucleic acid species from bacillus subtilis by use of chemical modification. 19724339674
semi-in vitro repair of radiation-induced damage in transforming dna of bacillus subtilis. 19724339851
the structural analysis and enzymic synthesis of a pentasaccharide alpha-limit dextrin formed from amylopectin by bacillus subtilis alpha-amylase. 19724340184
spore formation and germination of clostridium perfringens in the digestive tract of holoxenic and axenic mice. 19724340357
effects of acetate and other short-chain fatty acids on sugar and amino acid uptake of bacillus subtilis.acetate and other short chain n-fatty acids (c(1)-c(6)) inhibit strongly the uptake of l-serine or other l-amino acids but inhibit only weakly that of alpha-methylglucoside or fructose, whether measured in whole cells of bacillus subtilis or in membrane vesicles that have been energized with reduced nicotinamide adenine dinucleotide (nadh), l-alpha-glycerol phosphate, or ascorbate plus phenazine methosulfate. the acetate inhibition is noncompetitive, as was shown for l-alpha-aminoisobutyric acid ...19724340866
characterization of the specificity of intracellular phosphodiesterases in bacillus subtilis. 19724341592
distribution of pyrimidine oligonucleotides in strands l and h of bacillus subtilis dna.the distribution of pyrimidine oligodeoxynucleotide clusters in l and h strands of bacillus subtilis dna separated by methylated albumin-kieselguhr has been determined. preparations of native and single-stranded dna were degraded with diphenylamine in formic acid, and the released isostichs with the general formula of py(n)p(n+1) were separated on deae-cellulose by chain length. eleven isostichs were obtained for strands l and h in unequal proportions. each isostich fraction was subfractionated ...19724341707
measurement of beta-lactamase activity and rate of inactivation of penicillins by a ph-stat alkalimetric titration method. 19724342044
phosphodiesterase and nucleoside-phosphomonoesterase activities in b. subtilis during sporulation. 19724342230
in vitro and host-mediated "rec-assay" procedures for screening chemical mutagens; and phloxine, a mutagenic red dye detected. 19724342303
observations on the post-transcriptionally modified nucleotides in the 16s ribosomal ribonucleic acid.the 16s (18s) ribosomal ribonucleic acids from a number of organisms were screened for the presence of (some of) the post-transcriptionally modified oligomers found in escherichia coli 16s ribosomal ribonucleic acid. all prokaryotic 16s species contained all of the modified oligomers tested, with the sole exception that one such oligomer was missing in alcaligenes faecalis. the post-transcriptional modifications in all of these oligomers except one appear to occur at the later stagesin ribosomal ...19724342811
peptides from a mycobacillin-synthesizing cell-free system.in a cell-free system from bacillus subtilis b(3), atp-p(i) exchange was catalysed by l-proline at a ph optimum of 7.2. further stimulation by component amino acids of mycobacillin was inhibited by deprivation from the synthesizing system of even a single amino acid occurring at any point of the cyclic peptide. this inhibition, however, decreased with the distance in the molecule of the given amino acid from l-proline. peptides containing respectively two, three, four, five and six amino acids w ...19724343664
five penicillin-binding components occur in bacillus subtilis membranes. 19724344991
[functional morphology of the bacterial cell]. 19724345136
analysis of taxonomic characteristics of highly active viomycin-producing mutants of streptomyces griseus var. purpureus. 19724345459
thermal injury and recovery of bacillus subtilis.exposure of bacillus subtilis nctc 8236 to sublethal temperatures produced a change in the sensitivity of the organism to salt and polymyxin. after 30 min at 47 c, 90% of the population was unable to grow on a modified sulfite polymyxin sulfadiazine agar containing an added 1% nacl, 1% glucose, and 1% asparagine. the data presented demonstrate that thermal injury results in degradation of both 16s and 23s ribonucleic acid (rna) and in damage to the cell membrane, suggested by leakage into the he ...19724346627
formation of antibody in rabbit spleen cell cultures stimulated with immunogenic rna. 19724337671
concerning the production of free radicals in proteins by ultraviolet light. 19724337770
serine biosynthesis and its regulation in bacillus subtilis.cell-free extracts of bacillus subtilis strains gsy and 168 convert (14)c-phosphoglycerate to (14)c-serine phosphate and (14)c-serine. these reactions indicate a functional phosphorylated pathway for serine biosynthesis in these cells. the addition of serine to the incubation mixture inhibited the formation of both radioactive products. extracts of mutant strains that require serine for growth lacked the capacity to synthesize serine phosphate, confirming that the phosphorylated pathway was the ...19724337849
a quantitative microbiological determination of 6-aminopenicillanic acid. 19724338004
the effects of various cure cycles upon the viability of bacillus subtilis var. niger spores within solid propellant. 19724338866
concentration effect of bisulfite on the inactivation of transforming activity of dna. 19724339404
[the cytochromes of cytoplasmic and mesosomal membranes of bacillus subtilis]. 19724335841
inactivation of an alkaline bacillopeptidase by pentasodium triphosphate. 19724335856
incorporation of water oxygens into intracellular nucleotides and rna. i. predominantly non-hydrolytic rna turnover in bacillus subtilis. 19724336697
the influence of relative humidity on the aerosol stability of different strains of foot-and-mouth disease virus suspended in saliva. 19724337217
[experimental study of the antibacterial action of 7-chloro-7-deoxylincomycin]. 19724348897
semisynthetic -lactam antibiotics. 1. acylation of 6-aminopenicillanic acid with activated derivatives of -sulfophenylacetic acid. 19724347548
isolation and some distinctive properties of a new type of recombination-deficient mutant of bacillus subtilis. 19724349761
the radioprotective effect of dimethyl sulfoxide on bacillus subtilis cultures. 19724219273
structure of the peptidoglycan from spores of bacillus subtilis. 19724259915
medical problems in the detergent industry caused by proteolytic enzymes from bacillus subtilis. 19724260199
isolation of a high-molecular-weight hybrid between ribosomal rna and dna. 19724263474
comparison of two transformation systems for the assay of the neurospora photoreactivating enzyme. 19724263773
the disinfecting activity of methyl bromide on various microbes and infected materials under controlled conditions. 19724263775
[bacteriophage receptor--cell surface structure of the bacteria as the site of gene acceptance]. 19724265206
blocking of bacteriophage receptor sites by concanavalin a. 19724266463
correlates of skin test reactions to bacillus subtilis enzyme preparations. 19724257104
freeze-etching and dental research. 19724272046
the genetics of bacterial ribosomes. 19724269096
mode of action of a staphylococcus epidermidis bacteriocin.staphylococcin 1580, a bacteriocin produced by staphylococcus epidermidis 1580, is bactericidal to sensitive cells of many gram-positive bacteria and stable staphylococcal l-forms. the bacteriocin inhibited simultaneously the syntheses of deoxyribonucleic acid, ribonucleic acid, and protein, and caused neither degradation of deoxyribonucleic acid nor induction of phages in lysogenic, sensitive cells. after 1 hr of treatment, extensive degradation of ribonucleic acid occurred, which was accompani ...19724274969
[effect of the toxic metabolites of bacillus subtilis-mesentericus on tumorous and normal cells in tissue culture]. 19724208819
[newly discovered sugars in the specific polysaccharides of bacteria]. 19724208820
factors influencing the microbiological assay of tobramycin.tobramycin belongs to the aminoglycoside class of antibiotics. assay procedures were investigated to determine the most suitable methods for the assay of tobramycin in blood, urine, and pharmaceutical preparations. the agar-plate assay was the method of choice for determinations in urine and serum. the turbidimetric assay was selected for the assay of pharmaceutical preparations. an extraction technique is described that minimizes problems encountered in the estimation of tobramycin in urine. sa ...19724208898
regulated biosynthesis of protease and alpha-amylase in bacillus subtilis. 19724206761
the mechanism of transfection. kinetics and nature of b. subtilis transfection by phage sp-50 desoxyribonucleic acid. 19724207744
[biosynthesis of alpha-amylase by microorganisms]. 19724207888
[autolysis of bacterial cell surface and its physiology (biosynthesis)]. 19724143920
loss of biological activity of bacteriophage 2c and degradation of its dna in storage. 19724143992
the influence of temperate bacteriophage phi105 on transformation and transfection in bacillus subtilis. 19724196974
in vitro synthesis of dna spontaneously released by bacteria or frog auricles. 19724196378
[methods for determining the proteolytic activity of rennet preparations]. 19724196273
[effect of the antibiotics resistomycin and resistoflavin on growth, nucleic acid and protein synthesis in bacillus subtilis]. 19724197364
effect of aflatoxins on microorganisms. 19724197365
[evaluation of blood levels following oral administration of penicillin v-potassium]. 19724197738
[formation of extracellular rnases by microorganisms on a synthetic medium]. 19724197399
[toxic properties of the metabolites of some saprophytic bacteria]. 19724197401
[study of the antibiotic activity of mycetes isolated from the soil of various regions of bulgaria. i]. 19724197602
the mode of action of sterinol on microorganisms: effect on the external layers of bacterial cells. 19724197995
[purification and properties of exocellular levan-sucrase from bacillus subtilis marburg]. 19724200404
the location of n-acetylgalactosamine in the walls of bacillus subtilis 168.the n-acetylgalactosamine in the walls of bacillus subtilis 168 occurs in two polymers. one of these contains n-acetylgalactosamine, glucose and phosphorus and is attached to the peptidoglycan through an alkali-labile bond; preliminary studies indicate that a repeating unit of this polymer is glucosyl-n-acetylgalactosamine 1-phosphate. n-acetylgalactosamine is also associated with the peptidoglycan in a component that is not converted into the free sugar or other soluble compounds on treatment o ...19724198356
[fundamental and clinical evaluation of lividomycin]. 19724198943
kinetic analysis of the base sequence heterogeneity of rna molecules by rna-dna hybridization. 19724198952
[establishment of the genetic transformation system from tryptophan auxotrophy to protorophy in bacillus subtilis 168]. 19724199202
[studies on the isolation and elucidation of constitution of the rhyodomycin antibiotic agent in the streptomyces strain ja 8467]. 19724198117
sporulation in bacillus subtilis. properties and time of synthesis of alkali-soluble protein of the spore coat.an alkali-extractable protein fraction comprising 6% of the dry weight of the spore can be removed from spores of bacillus subtilis 168. three different extraction procedures each yield at least one similar protein. extracted protein behaved as a single species on ion-exchange chromatography or gel filtration, but two polypeptides were found on electrophoresis. comparison of molecular weights on electrophoresis and by sucrosegradient analysis suggests that the protein(s) undergo aggregation into ...19724198082
[biosynthesis and accumulation of dipicolinic acid in spore-forming bacteria. 2. isolation of an active compound catalyzing the synthesis of dipicolinic acid from the diketopimelate-nh3 complex]. 19724199419
[factors facilitating heteromorphism and competence in the genetic transformation of bacillus subtilis]. 19724199499
screening tests for argininosuccinic aciduria, orotic aciduria, and other inherited enzyme deficiencies using dried blood specimens. 19724199795
[the isoelectric point of extracellular proteases of certain bacterial species]. 19724200183
deoxyribonucleic acid distribution in bacillus subtilis independent of cell elongation.a temperature-sensitive dna(-) mutant of bacillus subtilis has been studied during the resumption of deoxyribonucleic acid (dna) synthesis following a 45 to 30 c temperature shift. for several hours after return to 30 c, dna synthesis proceeds although the cells fail to elongate appreciably. autoradiographs of cell populations synthesizing dna during the recovery period demonstrate that dna can become distributed to previously unoccupied regions along the cell length. by varying the labeling reg ...19724204904
initiation of bacillus subtilis ribonucleic acid polymerase on deoxyribonucleic acid from bacteriophages 2c, phi 29, t4, and lambda.ribonucleic acid (rna) synthesis primed by bacteriophage t4 or lambda deoxyribonucleic acid (dna) with bacillus subtilis rna polymerase is severely inhibited by high ionic strength. in contrast, rna synthesis on b. subtilis bacteriophage 2c, spo1, or phi29 dna is only moderately affected under similar conditions. the basis of this inhibition lies in the inability of the enzyme to initiate rna chains with adenosine triphosphate or guanosine triphosphate (atp, gtp). binding to templates and the ra ...19724204905
genetically controlled removal of "spore photoproduct" from deoxyribonucleic acid of ultraviolet-irradiated bacillus subtilis spores.previous genetic analysis indicated that at least two genes determine the ultraviolet (uv) sensitivity of bacillus subtilis spores. the present study shows that these genes independently control two distinguishable processes for removing uv-induced spore photoproduct (5-thyminyl-5,6-dihydrothymine, or tdht) from spore deoxyribonucleic acid. the first, is a spore repair mechanism by which tdht is removed rapidly without appearing in acid-soluble form. this mechanism, which is demonstrated in both ...19724204907
division site regulation in a temperature-sensitive mutant of bacillus subtilis.division site location was measured in bacillus subtilis clones grown from spores at 30 and 45 c. regulation of division location is lost in mutant 168ts-151 at 45 c.19724204908
mapping of rod mutants of bacillus subtilis.nine class a salt-dependent rod mutants were mapped on the bacillus subtilis genome by pbs1-mediated transduction. they are distributed into two small linkage groups designated rod b and rod c; mutations in rod b are over 80% cotransducible with phea and different mutations in rod c are 12 to 21% cotransducible with hisa. it is established that neither rod b nor rod c is linked by transformation to the other identified rod mutations present in 168-ts-200b and 8332 glu(-). it is hypothesized that ...19724204911
synthesis of pulcherriminic acid by bacillus subtilis.the pathway of pulcherriminic acid synthesis in bacillus subtilis strains am and am-l11 (a leucine-requiring auxotroph) was investigated. determinations of radioactivity in pulcherriminic acid synthesized by cells growing in media containing (14)c-labeled amino acids indicated that b. subtilis produced pulcherriminic acid from l-leucine. the organism utilized the carbon skeletons of two l-leucine molecules to synthesize one molecule of pulcherriminic acid. similar results were obtained with star ...19724204912
sporulation of tricarboxylic acid cycle mutants of bacillus subtilis.a mutant of bacillus subtilis 168 lacking aconitase (ec 4.2.1.3) was found to be blocked at stage 0 or i of sporulation. although adenosine triphosphate levels, which normally decrease in tricarboxylic acid cycle mutants at the completion of exponential growth, could be maintained at higher levels by feeding metabolizable carbon sources, this did not permit the cells to progress further into the sporulation sequence. when post-exponential-phase cells of mutants blocked in the first half of the t ...19724110146
temperature-sensitive mutant of bacillus subtilis that accumulates membrane-associated protein inclusions.at 47 c, a temperature-sensitive mutant of bacillus subtilis 168 accumulates membrane-associated protein inclusions and exhibits a pleiotropic phenotype indicative of a defect in lipid synthesis. the mutant bacteria cease growing at 47 c, and the turbidity of the culture gradually declines. the lack of growth is not due to the death or lysis of the cells, since viability does not decrease for about 1 hr and the "lysis" can be delayed for several hours by increasing the osmotic pressure of the me ...19724110148
ultrastructural analysis of sporulation in a conditional serine protease mutant of bacillus subtilis.the morphological characteristics of wild-type bacillus subtilis and a temperature-sensitive serine protease derivative have been observed during vegetative and sporulation time periods. at 30 c wild-type and mutant cells grow and sporulate identically. at 47.5 c wild-type and mutant cells grow identically, but the mutant cells are blocked at stage 0 or i in the sporulation sequence. wild-type cells sporulate normally at 47.5 c.19724130426
[do aerobic sporers contain endotoxins which can be activated by trypsin digestion?]. 19724124591
[influence of thallium acetate on the growth of acholeplasmataceae, mycoplasmataceae, and some bacteria species]. 19724145172
[induction of dehydrogenase activity for branched amino acids in bacillus subtilis (brief report)]. 19724145586
[concentration of bleomycin in the brain tumor tissue determined by bioassay]. 19724118609
mechanism of resistance to 5-azacytidine in bacillus subtilis. i. isolation and some properties of mutants resistant to 5-azacytidine and 5-aza-2'-deoxycytidine. 19724118611
nucleic acid--specificity of bleomycin. 19724119299
mechanism of action of bleomycin. i. bacterial growth studies. 19724119359
Displaying items 3701 - 3800 of 32189