Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| activities of leishmania from human skin ulcers in small laboratory animals. | 1977 | 23653 | |
| the use of gvh methods in analysis of the b-complex. | 1977 | 24559 | |
| the detection of bacterial antigens by counter-immunoelectrophoresis in n. meningitidis, h. influenzae serotype b, s. pneumoniae infections. diagnostic value and evolutive aspect (in 216 cases) (author's transl). | using counterimmunoelectrophoresis (cie) the authors have assayed for soluble bacterial s. pneumoniae, n meningitidis group a, b, c. h. influenzae type b antigens, biological fluids in 216 patients (meningitis: 136; pneumonia: 76; miscellaneous: 4) during 16 months. because of heterogeneous recruiting (the bacteriology was carried out by different laboratories) the increase in aetiological diagnosis given by cie is only statistically valid for the bacteriologic negative group when blind antibiot ... | 1977 | 26041 |
| central antagonism of tyramine-induced systemic hypotension by mescaline. | 1977 | 22607 | |
| research of the soluble microbial substances in organic fluids for the rapid diagnosis of some infections and particularly of bacterial meningitis (author's transl). | a number of immunological and non-immunological techniques have been recently used to detect soluble microbial substances in body fluids of patients with acute meningitis, bacteremia, and lobar pneumonia. by the immunological methods capsular highly polymerized polisaccharide group- or type-specific antigens of the most common c. n. s. pathogens (n. meningitidis a, b, and c; str. pneumoniae, h. influenzae type b, e. coli k1, mucoid pseudomonas, cryptococcus neoformans) can be detected and quanti ... | 1977 | 28697 |
| rapid detection of chloramphenicol resistance in haemophilus influenzae. | 1977 | 74780 | |
| frequency of e. coli k antigens in urinary-tract infections in children. | the somatic (o) and casular (k) antigens of escherichia coli from the urine of patients with acute pyelonephritis, acute cystitis, and asymptomatic bacteriuria, and in the faeces of healthy schoolchildren have been investigated. typing antisera for sixteen capsular acidic polysaccharide k antigens were used, and five (numbers 1, 2, 3, 12, and 13) accounted for 70% of isolates from patients with acute pyelonephritis. these five k antigens were found to a lesser extent in the three other study gro ... | 1977 | 66470 |
| counterimmunoelectrophoresis in the diagnosis of bacterial meningitis. | the aim of the present study was to investigate whether counterimmunoelectrophoresis (cie) would facilitate the rapid, etiological diagnosis of bacterial meningitis when used in parallel with other routine methods in a medical bacteriological laboratory. of 3,674 consecutive specimens of cerebrospinal fluid (csf) received at the department of diagnostic bacteriology, statens seruminstitu, 283 specimens (each representing one patient) were selected for examination by cie on the basis of the follo ... | 1977 | 67124 |
| degradation of transforming and transfecting dna by the restriction endonucleases of type i and type ii isolated from haemophilus influenzae. | the restriction endonucleases of type i and ii from haemophilus influenzae were studied for their activity on transforming and transfecting dna. type i restriction enzyme from haemophilus influenzae rf, which requires adenosine 5'-triphosphate, reduced the size of unmodified bacterial dna from 66x106 daltons to approximately 18x106 daltons and did not attack modified dna. the action of this enzyme gives only a low level of inactivation of single and linked markers in the transforming dna. in con ... | 1977 | 67762 |
| etiopathogenetic studies in a patient with whipple's disease. | a patient is presented with whipple's disease. before treatment, haemophilus influenzae type e, sensitive to tetracycline was cultured from multiple small intestinal biopsies. this isolated micro-organism was structurally similar to the one observed in the tissue. all further culture experiments during and after treatment proved negative except for one biopsy from which a tetracycline-resistant h. influenzae type-e mutant was isolated. the immunological disturbances, mainly characterized by cuta ... | 1977 | 67979 |
| antigens of haemophilus influenzae. | three antigenic preparations were obtained from a non-capsulated strain of haemophilus influenzae by ultrasonic disintegration, hot phenol extraction and from a fluid culture. they were designated h. influenzae cytoplasmic antigen (h(1-5); h. influenzae cell wall antigen (hcw); and h. influenzae culture filtrate antigen (hcf). studies showed that h(1-5) antigen contained heat stable and heat labile components. the heat stable fraction stained positively for polysaccharide, had a positive limulus ... | 1977 | 68839 |
| ovalbumin gene. action of restriction endonucleases upon dna coding sequence. | 1977 | 68956 | |
| haemophilus endocarditis. | 1977 | 69917 | |
| relationship between prophage induction and transformation efficiencies in haemophilus influenzae rd9. | 1977 | 70977 | |
| effect of heat on antigenicity and immunogenicity of the antigenic determinant shared by haemophilus influenzae type b and escherichia coli k100. | escherichia coli k100 produces an antigenic determinant similar to, or identical with, the capsular antigen of haemophilus influenzae type b. studies of the effects of heat on the immunogenicity, erythrocyte-modifying capacity, and antigenicity of this cross-reacting antigen (cra) revealed the following findings. immunization of rabbits with viable or formaldehyde-killed suspensions of e. coli k100, producing cra, engendered cra antibodies in significant titers, as demonstrated by hemagglutinati ... | 1977 | 71269 |
| chloramphenicol in haemophilus endocarditis. | 1977 | 72214 | |
| a rapid test for beta-lactamase production by haemophilus influenzae. | 1977 | 72244 | |
| [modification of the passive hemagglutination test for detection of the antibodies to capsular polysaccharide of haemophilus influenzae type b]. | 1977 | 72861 | |
| thymidine-requiring haemophilus influenzae and staphylococcus aureus. | 1977 | 72988 | |
| tumor biology of helium and heavy ions. | 1977 | 96044 | |
| mediators of immediate-type hypersensitivity in sputum from patients with chronic bronchitis and asthma. | mediators of immediate-type hypersensitivity were studied in the sputum of patients with chronic bronchitis. the same mediators were also measured in early-onset, skin-test-positive asthmatics, in late-onset, skin-test-negative asthmatics, and in patients with bronchial carcinoma, bronchiectasis, and pneumonia. sputum eosinophilia was a feature of bronchitics and asthmatics, whereas raised blood eosinophil levels were found only in the early-onset, skin-test-positive asthmatics. histamine and ig ... | 1977 | 95732 |
| [pathogenicity of the indigenous flora of the oral cavity]. | 1977 | 96398 | |
| effect of oophorectomy on estrogen receptors in rat mammary tumors induced by 7,12-dimethylbenz (a)anthracene. | 1977 | 96813 | |
| critical factors in the quality control of antilymphocyte globulin (alg). | 1977 | 98763 | |
| developmental patterns of peripheral nerve, myoneural junction and muscle: a review. | 1977 | 148071 | |
| mechanical properties of cardiac muscle from spontaneously hypertensive rats: accentuated aftercontractions. | 1977 | 139613 | |
| changes in calcium and magnesium in the kidneys of rats intoxicated with a single large dose of fluoride. | 1977 | 139709 | |
| a complete cleavage map of neurospora crassa mtdna obtained with endonucleases eco ri and bam hi. | a physical map of neurospora crassa mitochondrial dna has been constructed using specific fragments obtained with restriction endonucleases. the dna has 5 cleavage sites for endonuclease bam hi, 12 for endonuclease eco ri and more than 30 for endonuclease hind iii. the sequence of the eco ri and bam hi fragments has been established by analysis of partial fragments. by digestion of the eco ri fragments with bam hi, a complete overlapping map has been constructed. the position of the largest hind ... | 1977 | 139928 |
| transient-phase of atp hydrolysis by myosin sub-fragment-1 isoenzymes. | 1977 | 140068 | |
| recovery of preimplantation blastocysts in the squirrel monkey by a laparoscopic technique. | a laparoscopic uterine flushing technique has been developed for the recovery of preimplantation embryos from the squirrel monkey. fourteen adult female squirrel monkeys were induced to ovulate with 4 or 5 days' treatment with follicle-stimulating hormone (1 mg) followed by human chorionic gonadotropin (hcg) (500 iu). natural mating with a fertile male or artificial insemination was performed near the time of ovulation. thirty-six hours and eleven days after hcg administration, the females were ... | 1977 | 140077 |
| preparation of human immunoglobulin free of plasmin and anticomplement activities. | human igg separated by cohn fractionation showed variability in the content of aggregates, plasminogen and anticomplement activity. the plasminogen was removed or markedly reduced by affinity chromatography on sepharose-lysine. anticomplement activity was reduced by chromatography of cohn fraction ii on deae-cellulose. preparations of igg obtained by chromatography of intermediates from cohn fractionation (e.g. cohn fii + fiii or fii + fiii w) on deae-cellulose were devoid of aggregates, plasmin ... | 1977 | 140530 |
| [melkersson-rosenthal syndrome: stabilization by streptococcal desensitization]. | 1977 | 147303 | |
| skin test reactivity to h. influenzae antigens as an outcome of the antigen structure and the balance between humoral and cell-mediated immunity in rats. | 1977 | 141351 | |
| [bacteriological findings in chronic infantile tonsillitis (author's transl)]. | under general anaesthesia cultures were taken from infantile tonsils prior to t & a. the bacteriological results and the serological classification of hemophilus are questionning literature reports. according to our findings one must consider haemophilus influencae as a resident of the common oral flora. there was no significant difference culturing tonsils with or without repeated antibiotic treatment. hemophilus influencae combined with beta-hemolytic streptococci is common. immunological cons ... | 1977 | 141563 |
| a reconstituted na+ + k+ pump in liposomes containing purified (na+ + k+)-atpase from kidney medulla. | liposomes containing either purified or microsomal (na+,k+)-atpase preparations from lamb kidney medulla catalyzed atp-dependent transport of na+ and k+ with a ratio of approximately 3na+ to 2k+, which was inhibited by ouabain. similar results were obtained with liposomes containing a partially purified (na+,k+)-atpase from cardiac muscle. this contrasts with an earlier report by goldin and tong (j. biol. chem. 249, 5907-5915, 1974), in which liposomes containing purified dog kidney (na+,k+)-atp ... | 1977 | 141941 |
| suppressor cells in the spleen of tumor-allosensitized mice. | c57bl/6 mice were sensitized i.p. with 20 x 10(6) p-815 mastocytoma cells. spleen and lymph node cells from these tumor-allosensitized mice become hyporesponsive in mixed-lymphocyte culture. the hyporesponsiveness appears to be due to the presence of suppressor cells. these suppressor cells can be demonstrated by their ability to inhibit the mixed-lymphocyte culture reactivity of normal mouse spleen cells. suppressor activity in the spleen of tumor-allosensitized mice remains long after cytotoxi ... | 1977 | 141979 |
| the in vitro antibacterial activity of nine aminoglycosides and spectinomycin on clinical isolates of common gram-negative bacteria. | 1977 | 143468 | |
| [studies on restriction endonucleases (author's transl)]. | 1977 | 144930 | |
| [morphine self-administration added to food conditioning: methodological variant in rats]. | rats with permanent intra-jugular cannula are submitted to an alimentary operant reinforcement schedule with fixed ratio type fr 1, fr5, then fr 20. as a result, the animals are self administering (together with the alimentary inducer) a slow (about 5 sec) intravenous infusion of morphine (0.05 mg/kg). 20 per cent only of the experimental population exhibit a psychogenic dependance afterward. on the other hand, the animals for which morphine self-administration has been substituted to the alimen ... | 1977 | 145282 |
| [metabolism of nucleoside y in a mutant strain auxotrophic for guanine (gua 2 su+) of saccharomyces cerevisiae]. | the study of free nucleoside y metabolism in a mutant strain of saccharomyces cerevisiae seems to indicate that this component is not only provided by t-rna phe turnover. a peculiar physiologic activity-mitogenic type - may be connected with this observation. | 1977 | 145285 |
| heparin: a potent inhibitor of ovarian luteinizing hormone-sensitive adenylate cyclase. | 1977 | 145375 | |
| association of pantothenic acid with a protein subunit of yeast mitochondrial atpase. | 1977 | 145952 | |
| [swine influenza in antioquia, columbia]. | 1977 | 138429 | |
| [changes in allogeneic immune response of swine in the course of a liver allograft]. | pig liver allografts showed a typical rejection crisis. the degree of rejection depended on the sla-typing. despite sla-incompatibility pig liver allografts can be tolerated. short-term survivors showed an immunological hyporeactivity. long-term survivors reconstituted their cellular immune-reactions and developed an antibody which appeared to function as an antigen-antibody-complex or an anti-ia-antibody. | 1977 | 156111 |
| adenosine 5'-triphosphate-linked transhydrogenase in cytoplasmic membranes of colicin-treated and untreated escherichia coli. | the adenosine 5'-triphosphate (atp)-linked transhydrogenase reaction, present in the particulate fractions of escherichia coli, was previously shown to be inhibited in these fractions when the bacteria were treated with colicins k or el. the purpose of this study was to characterized the atp-linked transhydrogenase reaction and the colicin-caused inhibition of the reaction in purified cytoplasmic membranes. particulate fractions from bacteria treated or untreated with colicins were separated on ... | 1977 | 139401 |
| clearance of chylomicron triacylglycerol and cholesteryl ester from the plasma of streptozotocin-induced diabetic and hypercholesterolemic hypothyroid rats. | labeled chylomicrons in thoracic duct lymph were collected after test meals containing 14c cholesterol and 2-3h glyceryl trioleate and were given by intravenous injection to groups of control rats, rats made diabetic by treatment with streptozotocin, and rats made hypothyroid and hypercholesterolemic by a diet containing cholesterol, peanut oil, cholic acid, and thiouracil. in the diabetic rats clearances from the plasma of chylomicron triacylglycerol and cholesteryl ester were impaired. a large ... | 1977 | 139529 |
| changes in the activity of certain lysosomal enzymes in the blood serum and organs of rats subjected to fractionated whole body irradiation with 60 co. | 1977 | 97933 | |
| epidemiology and treatment of dog bites in ibadan: a 12-year retrospective study of cases seen at the university college hospital ibadan (1962-1973). | a retrospective epidemiological study was made of dog bite accidents seen at the casualty department of the university college hospital, ibadan, between 1 january 1962 and 31 december 1973. a variety of host, agent and environmental factors were analysed. the incidence per 1000 attendances was 11.5 with a male/female ratio of 57:43. majority of the bites occurred in the dry season and 75.4% of the victims were less than 20 years of age. 83.5% of the bites were inflicted on the extremities and 59 ... | 1977 | 97941 |
| absorption of dieldrin through monkey & dog skin. | 1977 | 97210 | |
| tropical diseases. | 1977 | 97727 | |
| tonic retinal influences in primates. | a type of unit discharge, termed "luxotonic," has been found in the striate cortex of unanesthetized squirrel monkeys and macaques.6, 21 the firing frequency of these units shows relatively little adaptation, continues indefinitely (hours), and reflects the level of diffuse illumination of the eye. the more numerous "photergic" units discharge more rapidly in the light, whereas "scotergic" units fire fastest in the dark (or at luminance levels below threshold for cones). luxotonic activity is ab ... | 1977 | 96720 |
| somatosensory restriction and behavioral development in stumptail monkeys. | 1977 | 96721 | |
| lipophilic o-antigens in rhodospirillum tenue. | lipopolysaccharides of eight wild-type strains of the phototrophic bacterium rhodospirillum tenue have been analyzed. all of the lipopolysaccharides are highly lipophilic. the compositions of preparations obtained by the phenol-water or by the phenol-chloroform-petroleum ether procedure are very similar. the polysaccharide moiety, obtained by mild acid hydrolysis of lipopolysaccharide, consists mainly of aldoheptoses: l-glycero-d-mannoheptose is present in all strains, whereas d-glycero-d-mannoh ... | 1977 | 95659 |
| the effect of lymphoma and other neoplasms on hepatic and plasma enzymes of the host rat. | considerable thymidine kinase and pyrroline-5-carboxylate reductase activities were found in the plasma of rats bearing a transplanted lymphoma; neither activity was detected in plasma of hosts carrying hepatic, renal, mammary, or submaxillary gland tumors. all host livers exhibited signs of biochemical immaturity as indicated by the appropriate increases or decreases in the concentrations of the nine enzymes measured. the extent and time schedule of the changes in host liver varied with the enz ... | 1977 | 187334 |
| quantification of apolipoprotein b in grossly normal human aorta. | a quantitiative electroimmunodiffusion (eid) assay was developed for apolipoprotein b (apob), the major apoprotein of human plasma low density lipoproteins (ldl) and very low density lipoproteins (vldl). specificity, sensitivity (30-200 ng) and reproducibility (11%) were established. we used this system to determine the amount of buffer-soluble apob in supernatant fractions from homogenates of the intima from grossly normal human aortas. assays of whole tissue minces yielded only one-third of th ... | 1977 | 187358 |
| postheparin plasma lipoprotein lipase and hepatic lipase in diabetes mellitus. relationship to plasma triglyceride metabolism. | the activity of two triglyceride lipases was determined by an immunochemical method in the postheparin plasma of 60 diabetic patients and of 47 age- and sex-matched nondiabetic control subjects. the results were related to the type of diabetes, to plasma triglyceride and insulin concentrations, to removal of exogenous fat from the blood, and to turnover of vldl-triglycerides . the mean postheparin plasma lipoprotein lipase (lpl) activity was decreased by 44 per cent (p less than 0.001) in patien ... | 1977 | 187516 |
| the potency ratio of galanthamine and neostigmine on the reversal of the tubocurarine block in the isolated rat diaphragm. | the potency ratio of galanthamine and neostigmine was studied on the rat phrenic nerve-diaphragm preparation. this ratio appeared to be about 18 on a weight base. the potency ratio in man in vivo, is about 20. hence we concluded that this potency ratio might mainly be due to the difference in potency on the neuromuscular transmission and not to kinetic differences. | 1977 | 201139 |
| demyelination in allergic and marek's disease virus induced neuritis. comparative electron microscopic studies. | patterns of demyelination were studied in sciatic nerves, spinal roots and ganglia of chickens afflicted with either marek's disease (md) or experimental allergic neuritis (ean). md was induced in susceptible chicks after hatching by inoculation of the jm strain of md herpes virus. tissues from these chickens were examined 7-83 days after infection. ean was studied 10-21 days after sensitization of 4 week old chickens to emulsions containing human peripheral nerve with complete freund's adjuvant ... | 1977 | 201143 |
| epstein-barr virus and cytomegalovirus antibodies in infectious mononucleosis. | a method has been evolved for the demonstration of epstein-barr virus (ebv) and cytomegalovirus (cmv) infection in 83 cases of infectious mononucleosis. serum samples were tested for ebv igm, anti-vca igg, anti-ebna, cmv igm and cmv igg antibodies. an acute-phase sample (or samples) and a convalescence sample were examined in each case, and in 44 cases an additional samples was examined 5-12 months after the illness. since the different antibodies showed characteristic differences in both titre ... | 1977 | 201153 |
| isolation and partial characterization of a glycine- and serine-rich polypeptide from human serum high-density lipoproteins (hdl). | lately, several minor polypeptides characterized by a high content of glycine and serum have been described in human serum lipoproteins. by column chromatography we have isolated a glycine- and serine-rich polypeptide from totally delipidized high-density lipoproteins, apo-hdl. the partial characterization of this polypeptide by total amino acid composition and by immunology utilizing monospecific antisera to polypeptides of human serum lipoproteins, would indicate a unique polypeptide. this low ... | 1977 | 203023 |
| [the effect of nalorphine on analgesia induced by peripheral stimulation]. | the blockade of effects induced by percutaneous peripheral stimulation were abolished by injection of an opiate antagonist as nalorphine. our results lead to the hypothesis that central and peripheral stimulations act by the same mechanism in producing blockade of noxious impulses. one may suggest that peripheral stimulations induce release of endogenous morphine-like substances which in turn give descending inhibition. | 1977 | 203372 |
| in vitro synthesis of herpes simplex virus dna in nuclei isolated from infected bsc 1 cells. | the synthesis of herpes simplex virus dna in isolated nuclei under in vitro conditions was found to be dependent on the addition of atp and an atp generating system to the reaction mixture. in vitro dna synthesis was stimulated and prolonged when p-hydroxymercuribenzoate was added to the isolated nuclei. under these improved conditions virus dna molecules which were initiated in vivo were completed in vitro, but most of the dna molecules synthesized in vitro sedimented in sucrose gradients more ... | 1977 | 190343 |
| effect of heterologous antimacrophage serum on growth of rous virus-induced sarcoma in the allogeneic and syngeneic system. | the effect of heterologous antimacrophage serum (ams) and normal rabbit serum (nrs) on the immune reaction against rous virus-induced sarcoma (rsl) was studied in rats. the growth of rsl sarcoma transplanted against the h-1 barrier in ams-treated rats was more progressive than in the untreated or nrs-treated control group. on the other hand, the growth of rsl sarcoma was significantly suppressed in syngeneic ams- or nrs-treated recipients compared to the untreated control rats. | 1977 | 190550 |
| unit activity in the cat visual cortex in the sleep--waking cycle. | changes in spontaneous unit activity in the primary visual cortex during the sleep-waking cycle were studied in chronic experiments on dark-adapted cats. in the cell poulation studied activity in states of wakefulness and of paradoxical sleep did not differ significantly either in mean discharge frequency or in pattern. activity of most cells in a state of slow sleep differed significantly from that in states of wakefulness and paradoxical sleep by the development of a "burst-pause" pattern in t ... | 1977 | 211461 |
| secretion of fluid and amylase in the perfused rat pancreas. | 1. the isolated rat pancreas was perfused with physiological salt solutions of varying composition. flow of pancreatic juice and output of amylase during rest and after stimulation with pure secretin, pure cholecystokinin-pancreozymin (cck-pz), caerulein or acetylcholine (ach) were measured. 2. basal fluid secretion was abolished replacing perfusion fluid na+ or cl- by tris+ or so42- respectively. readmission of na+ or cl- caused a transient increase above the normal control level of both fluid ... | 1977 | 191595 |
| rat adrenocortical dynamics. | 1. the dynamics of the adrenocortical response to adrenocorticotrophic hormone (acth) was studied in anaesthetized, acutely hypophysectomized male rats. 2. acth test-signals were applied either in a jugular vein ('intact infused preparation') or in the aorta through the coeliac artery with the aorta ligated below this artery ('isolated in situ perfused preparation'). the adrenocortical responses were measured directly in samples serially taken from the left adrenal vein. 3. tested acth signals w ... | 1977 | 191596 |
| bis-basic-substituted polycyclic aromatic compounds. a new class of antiviral agents. 8. bis-basic derivatives of carbazole, dibenzofuran, and dibenzothiophene. | a series of bisalkamine esters, bis-basic ethers, and bis-basic ketones of carbazole, n-ethylcarbazole, dibenzofuran, and dibenzothiophene was synthesized and evaluated for antiviral activity. the series also included two bis-basic alkanes of n-ethylcarbazole and one bis-basic carboxamide of dibenzofuran. structure-activity relationships indicated that within the carbazole and n-ethylcarbazole series the bisalkamine esters gave the most active derivatives while the bis-basic ketone derivatives o ... | 1977 | 191610 |
| mapping of the hhai and hinfi cleavage sites on simian virus 40 dna. | 1977 | 191618 | |
| photographic quantitation of dna in gel electrophoresis. | 1977 | 192103 | |
| hormonal and ionic control of the glycogenolytic cascade in rat liver. | 1. a parallel dose-dependent activation of histone kinase, phosphorylase kinase and phosphorylase was observed in isolated hepatocytes incubated in the presence of glucagon; the effect of suboptimal concentrations of glucagon was antagonized by insulin. 2. an activation of phosphorylase which was not accompanied by a stable change in the activity of phosphorylase kinase was observed in hepatocytes incubated with phenylephrine, isoproterenol or vasopressin as well as on decapitation of unanesthet ... | 1977 | 192206 |
| factors controlling the activities of phosphatidate phosphohydrolase and phosphatidate cytidylyltransferase. the effects of chlorpromazine, demethylimipramine, cinchocaine, norfenfluramine, mepyramine and magnesium ions. | 1. microsomal membranes from rat liver were incubated with atp, coa, mg2+, [14c]palmitate, f- and sn-glycerol 3-phosphate in order to label them with [14c]phosphatidate. these membranes were isolated and used in a second incubation in which [3h]ctp was present, and the simultaneous synthesis of [14c]diacylglycerol and [3h]cdp-diacylglycerol was measured. 2. the addition of phosphatidate phosphohydrolase, which had been partially purified from the particle-free supernatant, supplemented the activ ... | 1977 | 192211 |
| amino acid concentrating ability of slowly growing autochthonous hepatomas and host livers. | 1977 | 192232 | |
| inhibition of macromolecular synthesis in tumors by l-1-tosylamido-2-phenylethyl chloromethyl ketone. | 1977 | 192237 | |
| [depressor reactions to sural nerve stimulation in intact unanesthetized cats]. | changes in the arterial pressure, in the heart and respiratory rate evoked by the gastrocnemuis nerve stimulation were studied on conscious cats before and during intravenous injection of noradrenaline. stimulation of the gastrocnemius nerve increased the arterial pressure, the heart and respiratory rates. the same stimulation of the nerve during hypertension caused by noradrenaline injection led to the fall of arterial pressure and tachycardia. the depressor response failed to change under the ... | 1977 | 192391 |
| surface exposure of glycosaminoglycans in resting, growing and virus transformed 3t3 cells. | glycosaminoglycans (gag's) were released by trypsin from the surface of cultured mouse cells (3t3) in two different growing states: during log-growth phase and during resting due to serum starvation. doubly labelled molecules from resting cells were compared with those from growing as well as from trnsformed cells. reproducible differences in the elution pattern during ion exchange chromatography and in susceptibility to specific hydrolytic enzymes have been demonstrated: the gags pattern of gro ... | 1977 | 192739 |
| failure to find beta-adrenergic receptor binding in guinea pig cerebral cortex with [3h]dihydroalprenolol. | 1977 | 193615 | |
| effects of aliphatic aldehyde metabolism on protein synthesis and thiol compounds in rat liver and hepatoma induced by 4-dimethylaminoazobenzene. | 1977 | 193635 | |
| regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors. | the effect of phenoxybenzamine (pba), desmethylimipramine (dmi), clonidine (clnd), sotalol (stl), and isoproterenol (ispr) on the release of endogenous norepinephrine (ne) from the heart on right cardioaccelerator nerve stimulation was studied in anesthetized dogs. under control conditions, the catecholamine levels in coronary sinus blood increased linearly with increasing frequencies of stimulation up to 10 hz and did not increase further at 30 hz. the release of ne was markedly enhanced after ... | 1977 | 193655 |
| [effect of conditioned reflex factors on the motor and bioelectrical activity of the stomach in small ruminants under the influence of acth]. | 1977 | 193740 | |
| the effect of shearing of xc dna on its rsv transfecting activity. | xc dna fragments having the average molecular weight of 10(7) daltons were obtained by hydrodynamic shearing followed by sucrose gradient centrifugation or budr treatment of xc cells used for dna preparation. such dna molecules, even after long-term storage, were found to be active in transfection. | 1977 | 193741 |
| glucose-induced proinsulin biosynthesis. role of islet cyclic amp. | 1977 | 193750 | |
| phosphofructokinase (isozymes) activation by theophylline or by 3',5' cyclic amp administration. | phosphofructokinase activity of rat thyroid, kidney and muscle can be enhanced by in vivo administration of theophylline or cyclic amp. this enhancement occurs in the different tissues to a different extent depending on the tissue-specific isozymes. thyroid and muscle phosphofructokinase which is mainly a-type, is strongly stimulated after administering theophylline in the drinking water over a 8 days period. the kidney enzyme which encompasses about 50% of each a and b type is activated to a le ... | 1977 | 193771 |
| effect of storage, different media constituents and dilution of axenic medium on the growth of axenic culture of entamoeba histolytica. | 1977 | 193783 | |
| characterization of antigens from type a and b yeast cells of histoplasma capsulatum. | the antigenic composition of cytoplasmic extract and culture filtrate antigens of type a and b yeast cells of histoplasma capsulatum grown in a synthetic medium was studied. these preparations from type a and b yeast cells contained varying amounts of protein, carbohydrates, and protein-carbohydrate complexes. the antigenic analysis of these preparations was performed by antigen-antiserum absorption with subsequent immunodiffusion and cross-immunoelectrophoresis with absorption in situ in an int ... | 1977 | 193788 |
| human nasal epithelial cell culture system: evaluation of response to human interferons. | this report describes the response of human nasal epithelial cells to exogenously applied human interferon (if). to measure the response, a system developed to study human nasal epithelial cells in vitro was used. nasal epithelial cells responded equally to both leukocyte and fibroblast if, with development of resistance to virus replication that was time and dose dependent. cells required contact with 1,000 u of if (400 69/19 reference units) for 4 h to produce consistently a significant reduct ... | 1977 | 193789 |
| affinity of sendai virus for the inner ear of mice. | the direct immunofluorescent antibody method revealed that sendai virus, which was thought to be most prevalent in respiratory diseases in mice, infected the inner ear of mice when the virus was injected intracerebrally. specific immunofluorescence that indicated the presence of antigens of sendai virus was observed in both perilymphatic and endolymphatic structures. the routes of virus spread are discussed. this experimental study, using newborn mice and sendai virus, may be useful for the inve ... | 1977 | 193797 |
| histopathological changes in mice treated with extracts of the histamine-sensitizing factor of bordetella pertussis. | the histamine-sensitizing factor (hsf) of bordetella pertussis was isolated in a highly purified form. in addition to inducing profound sensitization to histamine, it also caused a significant lymphocytosis and produced an enhancement of reaginic antibody production in animals upon immunization with antigen. biologically active doses of hsf produced significant pathological changes in mice including congestion and edema of the lung and a marked depletion of cells in the thymus, white pulp of the ... | 1977 | 193800 |
| the effect of polymyxin b on outer membrane of serratia marcescens: activation and dissociation of outer membrane associated alkaline phosphatase. | 1977 | 193812 | |
| effects of chaotropic agents versus detergents on dihydroorotate dehydrogenase. | as chaotropic salts are generally believed to affect water structure in a manner which increases lipophilicity of water, they may seem to be capable of substituting for detergents in the solubilization of particulate enzyme. although solubilization either by detergents or by chaotropic salts has been demonstrated with several membrane proteins, the effects these agents have on the properties and activity of an enzyme may be quite different. this is illustrated by the effects on mammalian mitocho ... | 1977 | 193834 |
| determination of the nucleotide sequence of part of the regulatory region for the galactose operon from escherichia coli. | we have determined the sequence of 59 base pairs in the dna preceding the site for initiation of transcription in the galactose operon. dna from a lambdagal transducing phage was digested with restriction endonucleases to obtain a dna fragment from the gal regulatory region. this fragment extends from 59 base pairs prior to the transcription initiation site through the 45 base pairs which specify the 5'-terminal sequence of gal mrna. analyses of rna transcripts derived from this fragment and a v ... | 1977 | 193835 |
| the storage lipids in tangier disease. a physical chemical study. | the physical states and phase behavior of the lipids of the spleen, liver, and splenic artery from a 38-yr-old man with tangier disease were studied. many intracellular lipid droplets in the smectic liquid crystalline state were identified by polarizing microscopy in macrophages in both the spleen and liver, but not in the splenic artery. the droplets within individual cells melted sharply over a narrow temperature range, indicating a uniform lipid composition of the droplets of each cell. howev ... | 1977 | 193870 |
| characterization of purely ecotropic and amphotropic naturally occurring wild mouse leukemia viruses. | two new strains of murine leukemia virus, one (strain 4996) purely ecotropic and the other (strain 1313) purely amphotropic, were isolated from spontaneous lymphomas in aged wild mice (mus musculus). the 4996 virus is the first wild mouse field isolate which consists solely of ecotropic virus without the concomitant presence of amphotropic virus. the 1313 isolate is distinct in host range from seven other previously described wild mouse amphotropic isolates and is also the only murine leukemia v ... | 1977 | 197045 |
| isolation of simian virus 40 from rhesus monkeys (macaca mulatta) with spontaneous progressive multifocal leukoencephalopathy. | isolates of virus from the brain tissue of two naturally occurring cases of progressive multifocal leukoencephalopathy in rhesus monkeys (macaca mulatta) have been characterized. both isolates were demonstrated to be simian virus 40 (sv40) by serological tests and analysis of cleavage fragments of viral deoxyribonucleic acid produced by restriction endonuclease from haemophilus influenzae. sv40 virions and the nonvirion t antigen were demonstrated in the brain lesions of one monkey by the fluore ... | 1977 | 198489 |
| penetration of erythromycin stearate into maxillary sinus mucosa and secretion in chronic maxillary sinusitis. | the penetration of oral erythromycin stearate (abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. the average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml in secretion, and 1.8 microgram/ml in mucosa. these concentrations are highly effective against diplococci and most aerobic and anaerobic streptococci (mic value 0.06 microgram/ml) ... | 1977 | 199040 |
| isolation and characterization of bound ion-sulfur proteins from bacterial photosynthetic membranes. i. ferredoxins iii and iv from rhodospirillum rubrum chromatophores. | 1977 | 199587 | |
| the occurrence of antibody to babesia and to the virus of louping-ill in deer in scotland. | sera of wild red deer from 16 localities in scotland were tested by the indirect fluorescent antibody technique for antibody to babesia and by the haemagglutination inhibition test for antibody to the virus of louping-ill. babesial antibody was detected in sera from all localities in proportions ranging from 22 to 100 per cent. antibody to louping-ill virus could not be demonstrated in sera from five of the localities and in the other 11 was found less frequently than was antibody to babesia. se ... | 1977 | 200997 |
| [effect of thyroxine, insulin and cholesterol on the amount of cyclic adenosine monophosphate in normal and oncornavirus infected cells]. | the intracellular concentration of cyclic amp in normal cells and in cells infected with the rous sarcoma virus (chicken fibroblasts) was determined by the method of saturation analysis (method of concurrent binding with protein). thyroxine (2 mcg/ml) increased the level of cyclic amp both in normal and infected cells, insulin (2 mcg/ml) decreased the concentration of cyclic amp in infected cells, but cholesterol (5 mcg/ml) exerted no effect on this parameter in infected cells. the data are disc ... | 1977 | 201057 |
| [laryngotracheitis syndrome in acute respiratory-viral infections in children]. | 1977 | 201074 | |
| [activity of anatoxins against infectious enterotoxemia of sheep, prepared with different adjuvants]. | 1977 | 201079 | |
| [rna-synthesizing complex of the sendai virus in the nucleoli of infected erlich ascitic carcinoma cells]. | a virus-specific complex with sedimentation constant of 250s and buoyant density 1.35 g/cm3 in cesium chloride density gradient is formed within 20--24 hours after infection in nucleoli of ehrlich ascitic carcinoma cells infected with sendai virus. the complex contains a rapidly sedimenting rna (70--90s) which is about 50% stable to rn-ase. the complex has rna-polymerase activity in a cell-free system; the product of the rna-polymerase reaction is a rna with sedimentation constant 50s. it is sug ... | 1977 | 201099 |