Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| treatment outcomes and prognostic features in adenoid cystic carcinoma originated from the head and neck. | surgery is the main treatment modality for adenoid cystic carcinoma (acc) originated from the head and neck. however, the extensive local infiltrative and perineural spread related to this malignancy often cause difficulty to achieve high tumor control. the aim of this study is to evaluate the efficacy of postoperative radiotherapy (rt) in acc, and to identify prognostic variables associated with treatment outcomes. a retrospective review of 101 patients diagnosed with acc in the head and neck r ... | 2011 | 22209446 |
| redox status and pro-survival/pro-apoptotic protein expression in the early cardiac hypertrophy induced by experimental hyperthyroidism. | this study was conducted to analyse the redox status and redox-sensitive proteins that may contribute to a non-genomic mechanism of cardiac hypertrophy induction by hyperthyroidism. wistar rats, treated with l-thyroxine (t4) during 2 weeks (12 mg·l(-1) in drinking water), presented cardiac hypertrophy (68% higher than control), without signals of liver or lung congestion. myocardial reduction of the reduced glutathione: oxidized glutathione (gssg) ratio (45%) (redox status) and elevation in hydr ... | 2011 | 21989893 |
| [Preoperative staging MRI for rectal cancer and pathologic correlation]. | Our aim is to asses the accuracy of MRI for preoperative rectal cancer staging and to establish a histopathologic correlation. | 2011 | 21904400 |
| four-week neoadjuvant intensity-modulated radiation therapy with concurrent capecitabine and oxaliplatin in locally advanced rectal cancer patients: a validation phase ii trial. | purpose: to validate tolerance and pathological complete response rate (pcr) of a 4-week preoperative course of intensity-modulated radiation therapy (imrt) with concurrent capecitabine and oxaliplatin (capox) in patients with locally advanced rectal cancer. methods and materials: patients with t3 to t4 and/or n+ rectal cancer received preoperative imrt (47.5 gy in 19 fractions) with concurrent capecitabine (825 mg/m(2) b.i.d., monday to friday) and oxaliplatin (60 mg/m(2) on days 1, 8, and 15). ... | 2011 | 22079731 |
| decreased cognitive functioning in patients with advanced oral squamous cell carcinoma. | cognitive impairment causes a delay in diagnosis and treatment of the various cancer entities, resulting in reduced surgical outcomes and patient survival. however, no investigations have been carried out as to whether an association exists between cognitive functioning and tumour size in patients with oral squamous cell carcinoma (oscc). in this study, 46 patients with oscc were evaluated by using a screening test for dementia, consisting of a combination of the mini-mental state examination an ... | 2011 | 21903447 |
| maternal thyroid function during the second half of pregnancy and child neurodevelopment at 6, 12, 24, and 60 months of age. | although evidence suggests that maternal hypothyroidism and mild hypothyroxinemia during the first half of pregnancy alters fetal neurodevelopment among euthyroid offspring, little data are available from later in gestation. in this study, we measured free t4 using direct equilibrium dialysis, as well as total t4 and tsh in 287 pregnant women at 27 weeks' gestation. we also assessed cognition, memory, language, motor functioning, and behavior in their children at 6, 12, 24, and 60 months of age. ... | 2011 | 22132346 |
| structure and dynamics of a conformationally constrained nitroxide side chain and applications in epr spectroscopy. | a disulfide-linked nitroxide side chain (r1) is the most widely used spin label for determining protein topology, mapping structural changes, and characterizing nanosecond backbone motions by site-directed spin labeling. although the internal motion of r1 and the number of preferred rotamers are limited, translating interspin distance measurements and spatial orientation information into structural constraints is challenging. here, we introduce a highly constrained nitroxide side chain designate ... | 2011 | 21911399 |
| prediction of enzyme mutant activity using computational mutagenesis and incremental transduction. | wet laboratory mutagenesis to determine enzyme activity changes is expensive and time consuming. this paper expands on standard one-shot learning by proposing an incremental transductive method (t2brf) for the prediction of enzyme mutant activity during mutagenesis using delaunay tessellation and 4-body statistical potentials for representation. incremental learning is in tune with both escience and actual experimentation, as it accounts for cumulative annotation effects of enzyme mutant activit ... | 2011 | 22007208 |
| 55.1, a gene of unknown function of phage T4, impacts on Escherichia coli folate metabolism and blocks DNA repair by the NER. | Phage T4, the archetype of lytic bacterial viruses, needs only 62 genes to propagate under standard laboratory conditions. Interestingly, the T4 genome contains more than 100 putative genes of unknown function, with few detectable homologues in cellular genomes. To characterize this uncharted territory of genetic information, we have identified several T4 genes that prevent bacterial growth when expressed from plasmids under inducible conditions. Here, we report on the various phenotypes and mol ... | 2011 | 22029793 |
| structural conservation of the myoviridae phage tail sheath protein fold. | bacteriophage phikz is a giant phage that infects pseudomonas aeruginosa, a human pathogen. the phikz virion consists of a 1450 å diameter icosahedral head and a 2000 å-long contractile tail. the structure of the whole virus was previously reported, showing that its tail organization in the extended state is similar to the well-studied myovirus bacteriophage t4 tail. the crystal structure of a tail sheath protein fragment of phikz was determined to 2.4 å resolution. furthermore, crystal structur ... | 2011 | 22153511 |
| Caveolin-1 as a potential high-risk prostate cancer biomarker. | Current diagnostic techniques of prostate cancer cannot efficiently distinguish the latent and low-risk forms from the high-risk significant forms of prostate cancer. Caveolin-1 (Cav-1), except other functions, plays an important role in cell transformation and the process of tumorigenesis. Furthermore, Cav-1 is involved in metastatic processes. It has also been shown that Cav-1 expression is induced under stress conditions, such as oxi ... | 2011 | 22159333 |
| the biomechanics of the pediatric and adult human thoracic spine. | a growing body of literature points out the relevance of the thoracic spine dynamics in understanding the thorax-restraint interaction as well as in determining the kinematics of the head and cervical spine. this study characterizes the dynamic response in bending of eight human spinal specimens (4 pediatric: ages 7 and 15 years, 4 adult: ages 48 and 52 years) from two sections along the thoracic spine (t2-t4 and t7-t9). each specimen consisted of three vertebral bodies connected by the correspo ... | 2011 | 22105396 |
| how a dna polymerase clamp loader opens a sliding clamp. | processive chromosomal replication relies on sliding dna clamps, which are loaded onto dna by pentameric clamp loader complexes belonging to the aaa+ family of adenosine triphosphatases (atpases). we present structures for the atp-bound state of the clamp loader complex from bacteriophage t4, bound to an open clamp and primer-template dna. the clamp loader traps a spiral conformation of the open clamp so that both the loader and the clamp match the helical symmetry of dna. one structure reveals ... | 2011 | 22194570 |
| Investigation of thyroid dysfunction in general practice is more likely in patients with high psychological morbidity. | BACKGROUND: Mild or subclinical hypothyroidism [raised thyroid-stimulating hormone (TSH) but normal free thyroxine (T4)] affects 5-10% of adults. Symptoms are non-specific and TSH levels are needed for diagnosis. OBJECTIVES: We explore the relationship between thyroid function and psychological distress and investigate the usefulness of an expert-designed Thyroid Symptom Questionnaire (TSQ) in identifying hypothyroidism. METHODS: DEPTH (DEPression and THyroid) is a cross-sectional study of 325 p ... | 2011 | 21890841 |
| [Administration of sugammadex to a patient with myasthenia gravis with fade of the train-of-four ratio]. | A 50-year-old man (weight 87 kg, height 171 cm) with myasthenia gravis (MG) was scheduled for extended thymectomy under general anesthesia. His preanesthetic train-of-four ratio (T4/T1) was 59%. The first twitch of the train-of-four (T1) was 130% after calibration. We administered rocuronium 10 mg (0.11 mg x kg(-1)) for tracheal intubation. Maximal suppression was achieved in 50 seconds. During the operation, we did continuous infusion of rocuronium to maintain T1 at 10%. We discontinued rocuron ... | 2011 | 21950042 |
| sephardic signature in haplogroup t mitochondrial dna. | a rare combination of mutations within mitochondrial dna subhaplogroup t2e is identified as affiliated with sephardic jews, a group that has received relatively little attention. four investigations were pursued: search of the motif in 250 000 control region records across 8 databases, comparison of frequencies of t subhaplogroups (t1, t2b, t2c, t2e, t4, t(*)) across 11 diverse populations, creation of a phylogenic median-joining network from public t2e control region entries, and analysis of on ... | 2011 | 22108605 |
| Value of Repeat Stimulated Thyroglobulin Testing in Patients with Differentiated Thyroid Carcinoma Considered to Be Free of Disease in the First Year After Ablation. | Background: In patients with differentiated thyroid carcinoma considered to be free of the disease after initial therapy, the appropriate timing or necessity of subsequent stimulated thyroglobulin (Tg) testing is uncertain. The objective of this study was to determine the value of a repeat stimulated Tg in patients considered to be free of disease 6-12 months after thyroid ablation, and also who continued to have serum Tg <1?ng/mL while on thyrotropin suppressive doses of thyroxine (T4) (Tg/T4), ... | 2011 | 22175271 |
| Kinematic analysis of kicking in young top-class soccer players. | The aim of this study was to describe the kinematic pattern of the kicking movement of young top-class soccer players focusing in examining the linear joint markers velocity of the leg kick and the segments angular position. | 2011 | 21904274 |
| Reproductive biomarkers to identify endocrine disruption in Clarias gariepinus exposed to 4-nonylphenol. | The present study investigated the hormones concentrations and gonads alterations of Clarias gariepinus caused by sublethel concentrations of 4-nonylphenol (0, 0.05, 0.08 and 0.1mg/l). The changes in the activities of the hormones after exposure to these sublethel doses of 4-nonylpenol referred to endocrine disruption in Clarias gariepinus in association with histopathological changes in reproductive tissues. The levels of thyroid stimulating hormone (TSH), triiodothyronine (T3), total thyroxine ... | 2011 | 22177982 |
| The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. | Background:Upregulation of the proto-oncogene plasminogen activator inhibitor-1 (PAI-1) is a common hallmark of various solid tumours, but the mechanisms controlling its expression are not fully understood.Methods:We investigate microRNAs (miRNAs) regulating PAI-1 in a panel of normal bladder urothelial biopsies, superficial Ta bladder tumours and invasive T1-T4 tumours using expression microarrays and qRT-PCR. The prognostic implications of PAI-1 deregulation are established by tissue microarra ... | 2011 | 22108519 |
| Initial PET/CT staging for choroidal melanoma: AJCC correlation and second nonocular primaries in 333 patients. | Purpose. To report on whole body positron emission tomography/computed tomography (PET/CT) screening for metastasis at diagnosis of primary uveal melanoma. Methods. Since August 2003, 333 consecutive patients were diagnosed with uveal melanoma and underwent whole body screening for metastatic disease with PET/CT along with liver function tests and physical examination. Abnormal findings prompted further biopsies, blood tests, imaging, or clinical evaluations for confirmation. The presence of met ... | 2011 | 21959680 |
| the presence of facial nerve weakness on diagnosis of a parotid gland malignant process. | the objectives of this article are to assess the frequency and significance of facial paralysis and undiagnosed nerve infiltration in patients with parotid malignancies. 103 patients with parotid gland malignancies were treated in a single institution, the tertiary center for ent at the university department in poznan between 1996 and 2006. facial palsy at the initial presentation was found in 32 patients. the stage of the primary tumor in the examined group of 103 patients is as follows: 20-t1, ... | 2011 | 22179671 |
| Prognostic significance of cyclooxygenase-2, epidermal growth factor receptor 1, and microvascular density in gastric cancer. | Gastric cancer remains a significant global health burden with poor treatment outcome. New treatment modalities that target inflammation, proliferation, and angiogenesis have been used in various cancers, including gastric cancer. We sought to study the pattern of expression of two important proteins, cyclooxygenase-2 and epidermal growth factor receptor, and their association with microvascular density, clinicopathological features, and survival in Arab Omani patients with gastric cancer. Forma ... | 2011 | 22048943 |
| whole-pelvis or bladder-only chemoradiation for lymph node-negative invasive bladder cancer: single-institution experience. | purpose: whole-pelvis (wp) concurrent chemoradiation (ccrt) is the standard bladder preserving option for patients with invasive bladder cancer. the standard practice is to treat elective pelvic lymph nodes, so our aim was to evaluate whether bladder-only (bo) ccrt leads to results similar to those obtained by standard wp-ccrt. methods and materials: patient eligibility included histopathologically proven muscle-invasive bladder cancer, lymph nodes negative (t2-t4, n-) by radiology, and maximal ... | 2011 | 21945107 |
| enantioselective cleavage of supercoiled plasmid dna catalyzed by chiral macrocyclic lanthanide(iii) complexes. | the enantiomers of the sm (iii), eu (iii) and yb (iii) complexes [lnl(no(3))(2)](no(3)) of a chiral hexaazamacrocycle were tested as catalysts for the hydrolytic cleavage of supercoiled plasmid dna. the catalytic activity was remarkably enantioselective; while the [lnl(ssss)(no(3))(2)](no(3)) enantiomers promoted the cleavage of plasmid pbr322 from the supercoiled form (sc) to the nicked form (nc), the [lnl(rrrr)(no(3))(2)](no(3)) enantiomers were inactive. kinetics of plasmid dna hydrolysis was ... | 2011 | 22169034 |
| A new strategy for the synthesis of bisaminoacylated tRNAs. | Tandemly activated tRNAs participate effectively in protein synthesis and exhibit superior chemical and biochemical stability compared to the more commonly used singly aminoacylated tRNAs. While several bisaminoacylated tRNAs have been prepared via the T4 RNA ligase-mediated condensation of bisaminoacylated pdCpAs and abbreviated tRNA transcripts (tRNA-C(OH)), the bisaminoacylated pdCpAs are difficult to prepare when using bulky amino acids. Described herein is a new strategy for preparing bisam ... | 2011 | 21861452 |
| continued reduction in the prevalence of retinopathy in adolescents with type 1 diabetes: role of insulin therapy and glycemic control. | to examine trends in microvascular complications in adolescents with type 1 diabetes between 1990 and 2009 in sydney, australia. | 2011 | 22025782 |
| Spinal Cord Intramedullary Pressure in Thoracic Kyphotic Deformity: A Cadaveric Study. | ABSTRACT: Study Design. In vitro cadaveric study of thoracic spinal cord intramedullary pressure (IMP) in kyphotic deformity.Objective. To define the relationship between thoracic spinal kyphotic deformity and spinal cord intramedullary pressure.Summary of Background Data. Previous studies of asymptomatic volunteers have revealed that there is wide variation in regional sagittal neutral upright thoracic spinal alignment with "normal" thoracic T4-T12 kyphosis ranging up to approximately +69° for ... | 2011 | 21857404 |
| [Effectiveness of neoadjuvant chemoradiotherapy of locally advanced rectal cancer in conjunction with local hyperthermia and metronidazole]. | Our study included 36 patients with hard fixed rectal tumors (T3, T4) who had received combined treatment at the Center's Clinics. On irrigoscopic evidence, lesions were more than 10 cm long. Radiotherapy was conducted thrice a week, STD of 4 Gy--TTD of 40 Gy; capecitabine, per os, 650 mg/m2 twice a day, days 1-22; oxaliplatin, 50 mg/m2, intravenously, days 3, 10 and 17; metronidazole in polymer composition, intrarectally, 10 mg/m2, twice, days 12 and 17 of radiotherapy; local hyperthermia (the ... | 2011 | 21882611 |
| adjuvant radiotherapy in the treatment of invasive intraductal papillary mucinous neoplasm of the pancreas: an analysis of the surveillance, epidemiology, and end results registry. | background: management and outcomes of patients with invasive intraductal papillary mucinous neoplasm (ipmn) of the pancreas are not well established. we investigated whether adjuvant radiotherapy (rt) improved cancer-specific survival (css) and overall survival (os) among patients undergoing surgical resection for invasive ipmn. methods: the surveillance, epidemiology, and end results (seer) registry was used in ... | 2011 | 22002799 |
| utilisation of iodine from different sources by sows and their progeny. | the aim of the study was to compare iodine utilization from different sources by sows and their progeny and the levels of t3 and t4 in their serum. | 2011 | 21876486 |
| [genetic diversity of major capsid genes (g23) of t4-type bacteriophages in natural environments--a review]. | during the past two decades, the genetic diversities of bacterial and fungal communities and their relationship with the inhabited environments were intensively studied with the development of molecular biological techniques. however, although bacteriophages are ubiquitous and more abundant than their hosts in biosphere, their diversity is still little known. in this paper, we targeted the major capsid genes (g23) of t4-type bacteriophages and reviewed the recent progress on their genetic divers ... | 2011 | 21866696 |
| guillain-barre syndrome presenting with sensory disturbance following a herpes virus infection: a case report. | abstract: introduction: we present a case of an unusual clinical manifestation of guillain-barre syndrome following a pre-existing herpes virus infection. although there have been several reports describing the co-existence of herpes virus infection and guillain-barre syndrome, we undertook a more in-depth study of the cross-reactivity between herpes viruses and recommend a follow-up study based on serology tests. case presentation: a 39-year-old healthy caucasian man with guillain-barre syndro ... | 2011 | 22136568 |
| [results of preoperative chemoradiotherapy for t4 rectal cancer]. | we reviewed clinical records of 11 cases with preoperative chemoradiotherapy to evaluate the clinical effectiveness of chemoradiotherapy for t4 rectal cancer. the preoperative radiotherapy consisted of 40-50 gy delivered in fractions of 1 .8- 2.0 gy per day, five days per week. a treatment of 5-fluorouracil, 500 mg/body per day intravenously, or oral uft-e (300 mg/m2) with l-leucovorin (75 mg) per day, or oral s-1 (80 mg/m2) per day five days per week, was given during radiotherapy. one patient ... | 2011 | 22202339 |
| transient changes in thyroid functions tests after zoledronic acid infusion. | zoledronic acid (za) induces an acute phase response in association with elevation of serum cytokines, which possibly alter the 3 types of iodothyronine deiodinase activity. we therefore studied the possible alteration in thyroid function tests by za. we investigated the acute changes in serum thyroid hormones, tsh, cortisol, white blood cells, crp, interleukin-6 (il-6) and tumor necrosis factor (tnf-α), before (0) and 1, 2 and 3 days after iv infusion of 5 mg za in 24 asymptomatic postmenopau ... | 2011 | 21891972 |
| bacteriophage t4 mota activator and the β-flap tip of rna polymerase target the same set of σ70 carboxyl-terminal residues. | sigma factors, the specificity subunits of rna polymerase, are involved in interactions with promoter dna, the core subunits of rna polymerase, and transcription factors. the bacteriophage t4-encoded activator, mota, is one such factor, which engages the c terminus of the escherichia coli housekeeping sigma factor, σ(70). mota functions in concert with a phage-encoded co-activator, asia, as a molecular switch. this process, termed sigma appropriation, inhibits host transcription while activating ... | 2011 | 21911499 |
| crystal structure of the bacteriophage t4 late-transcription coactivator gp33 with the β-subunit flap domain of escherichia coli rna polymerase. | activated transcription of the bacteriophage t4 late genes, which is coupled to concurrent dna replication, is accomplished by an initiation complex containing the host rna polymerase associated with two phage-encoded proteins, gp55 (the basal promoter specificity factor) and gp33 (the coactivator), as well as the dna-mounted sliding-clamp processivity factor of the phage t4 replisome (gp45, the activator). we have determined the 3.0 å-resolution x-ray crystal structure of gp33 complexed with it ... | 2011 | 22135460 |
| Central hypothyroidism. | Central hypothyroidism is defined as hypothyroidism due to insufficient stimulation by thyroid stimulating hormone (TSH) of an otherwise normal thyroid gland. It has an estimated prevalence of approximately 1 in 80,000 to 1 in 120,000. It can be secondary hypothyroidism (pituitary) or tertiary hypothyroidism (hypothalamus) in origin. In children, it is usually caused by craniopharyngiomas or previous cranial irradiation for brain tumors or hematological malignancies. In adults, it is usually due ... | 2011 | 21966662 |
| the effect of heating insufflation gas on acid-base alterations and core temperature during laparoscopic major abdominal surgery. | carbon dioxide (co(2)) has different biophysical properties under different thermal conditions, which may affect its rate of absorption in the blood and the related adverse events. the present study was aimed to investigate the effects of heating of co(2) on acid-base balance using stewart's physiochemical approach, and body temperature during laparoscopy. | 2011 | 22110878 |
| Production of the stable human histamine H(1) receptor in Pichia pastoris for structural determination. | G-protein coupled receptors (GPCRs) play essential roles in regulation of many physiological processes and are one of the major targets of pharmaceutical drugs. The 3D structure can provide important information for the understanding of GPCR function and the design of new drugs. However, the success of structure determination relies largely on the production of recombinant GPCRs, because the expression levels of GPCRs are very low in native tissues except rhodopsin. All non-rhodopsin GPCRs whose ... | 2011 | 21903167 |
| nanoliter droplet array for microrna detection based on enzymatic stem-loop probes ligation and sybr green real-time pcr. | in this paper, a nanoliter droplet array based on enzymatic stem-loop probes ligation and sybr green real-time pcr for quantification of microrna was developed. by employing t4 rna ligase 2 instead of t4 dna ligase, we designed simplified stem-loop probes to perform microrna-templated dna ligation and reduced the non-specific ligation of t4 dna ligase. sybr green i dye was employed instead of taqman probes in present miniaturized real-time pcr systems. specifically, we optimized the dosage of sy ... | 2011 | 21872015 |
| blood-based biomarkers of selenium and thyroid status indicate possible adverse biological effects of mercury and polychlorinated biphenyls in southern beaufort sea polar bears. | we examined biomarkers of selenium status (whole blood se; serum se; glutathione peroxidase activity) and thyroid status (concentrations and ratios of thyroxine, t4; tri-iodothyronine, t3; albumin) in polar bears to assess variations among cohorts, and relationships to circulating concentrations of contaminants. concentrations of total mercury (hg) in whole blood were similar among cohorts (prime aged males and females, older animals, ages≥16 years, and young animals, ages 1-5 years; 48.44±35. 8 ... | 2011 | 21903210 |
| Tripchlorolide induces cell death in lung cancer cells by autophagy. | It has been demonstrated that triptolide inhibits the growth of several types of cancer cells in vitro and prevents tumor growth in vivo by inducing apoptosis and autophagy. Here we showed that Tripchlorolide (T4) significantly suppressed the proliferation of A549 cells in a dose- and time-dependent manner. This suppressive effect was diminished when cells were pretreated with 3-Methylamphetamine (3-MA). After the cells were treated wit ... | 2011 | 22139090 |
| Effects of thyroxine replacement on endothelial function and carotid artery intima-media thickness in female patients with mild subclinical hypothyroidism. | Previous studies have suggested an association between subclinical hypothyroidism and coronary artery disease that could be related to changes in serum lipids or endothelial dysfunction. | 2011 | 21915478 |
| [t3, t4 pathologic fracture with incompletely paralysis caused by langerhans cell histiocytosis: a case report]. | 2011 | 22097135 | |
| Hydrazide reactive peptide tags for site-specific protein labeling. | New site-specific protein labeling (SSPL) reactions for targeting-specific, short peptides could be useful for the real-time detection of proteins inside of living cells. One SSPL approach matches bioorthogonal reagents with complementary peptides. Here, hydrazide reactive peptides were selected from phage-displayed libraries using reaction-based selections. Selection conditions included washes of varying pH and treatment with NaCNBH(3) in order to specifically select reactive carbonyl-containin ... | 2011 | 21905743 |
| Is the Kidney a Major Storage Site for Thyroxine as Thyroxine Glucuronide? | Background: Previous studies have shown that thyroxine (T4) is stored as T4 glucuronide (T4G) in the kidney, and that 24 hours after administration of [(125)I]T4 to mice, 17% of the radioactivity was present in the kidneys, whereas only 4% was found in the liver. The present study was carried out to determine the relative amounts of conjugated and unconjugated T4 and 3,5,3'-triiodothyronine (T3) in the kidney and liver, and whether the conjugated hormones are extracted from tissues using our est ... | 2011 | 22175240 |
| Impact of elective neck dissection on regional recurrence and survival in cN0 staged oral maxillary squamous cell carcinoma. | To evaluate the impact of elective neck dissection (END) on regional recurrence and survival in cN0 staged patients with maxillary squamous cell carcinoma (SCC). Eighty-six patients with maxillary SCC and clinically staged N0 cervical lymph-nodes were evaluated in this single center retrospective study. Seventy-four of 86 patients were included in this analysis, of which 36 patients were treated with END, 38 without END. Following END, pathohistologically verified regional lymph-nodes in the ini ... | 2011 | 21974917 |
| The development of articulatory awareness and the relationship between perception and production of the articulatory gesture. | To investigate the articulatory awareness of children with normal phonological development according to the variables gender, age and schooling, as well as to analyze their performances in speech perception and production tasks. | 2011 | 22012160 |
| [diffusion-weighted mr imaging in patients with rectal cancer: our initial experience]. | pre-surgical characterization of post-neoadjuvant residual tumor response in patients with rectal cancer by means of an imaging technique could be useful in order to determine the therapeutic strategy or observation. | 2011 | 22232997 |
| complete genome sequence and characterization of a broad-host range t4-like bacteriophage phias5 infecting aeromonas salmonicida subsp. salmonicida. | in this study, we report one lytic myoviridae bacteriophage (phage) infecting aeromonas salmonicida subsp. salmonicida. the phage (named as phias5) was isolated from environmental river waters in korea, and showed broad infectivity to other bacterial species in the family aeromonadaceae as well as antibiotic-resistant a. salmonicida subsp. salmonicida strains. the biological properties and complete genome of phias5 were simultaneously investigated. the complete genome of phias5 composed of linea ... | 2011 | 22226819 |
| [rocuronium vs vecuronium for neuromuscular block during transsternal thymectomy in the patient with myasthenia gravis]. | myasthenia gravis is an autoimmune disease marked by high titers of immunoglobulin g antibodies, which accelerate destruction of cholinergic receptors and interfere with neuromuscular transmission. this study aimed to determine whether neuromuscular function under a rocuronium block is different from function under a vecuronium block patients with myasthenia gravis and to describe extubation conditions in the operating room or the intensive care unit. | 2011 | 22263401 |
| efficacy and safety of concurrent chemoradiation with weekly cisplatin ± low-dose celecoxib in locally advanced undifferentiated nasopharyngeal carcinoma: a phase ii-iii clinical trial. | background: this is the first study that aimed to determine the efficacy and safety of concurrent chemoradiation with weekly cisplatin ± celecoxib 100 mg twice daily in locally advanced undifferentiated nasopharyngeal carcinoma. materials and methods: eligible patients had newly diagnosed locally advanced (t3-t4, and/or n2-n3, m0) undifferentiated nasopharyngeal carcinoma, no prior therapy, karnofsky performance status ≥ 70, and normal organ function. the patients were assigned to receive 7 wee ... | 2011 | 22269407 |
| low concentrations of bisphenol a suppress thyroid hormone receptor transcription through a nongenomic mechanism. | bisphenol (bpa) is one of the highest-volume chemicals produced worldwide, and human exposure to bpa is thought to be ubiquitous. various rodent and in vitro studies have shown that thyroid hormone (th) function can be impaired by bpa. however, it is still unknown if low concentrations of bpa can suppress the thyroid hormone receptor (tr) transcription. the present study aims to investigate the possible suppressing effects of low concentrations of bpa on tr transcription and the involved mechani ... | 2011 | 22227104 |
| [the expression and its potentially clinical significance of epha2 in nasopharyngeal carcinoma]. | to observe the expression of epha2, and investigate its correlation with the development, progression, invasion, metastasis, angiogenesis and prognosis in nasopharyngeal carcinoma(npc). | 2011 | 22256737 |
| effectiveness of adjuvant chemotherapy with 5-fu/leucovorin and prognosis in stage ii colon cancer. | the aims of this study were to investigate the survival results and the prognostic factors of adjuvant chemotherapy in stage ii colon cancer in the sparsity of korean data. | 2011 | 22259748 |
| 3,5-diiodo-l-thyronine increases resting metabolic rate and reduces body weight without undesirable side effects. | recently, it was demonstrated that 3,5-diiodo-l-thyronine (t2) stimulates the resting metabolic rate (rmr), and reduces body-weight gain of rats receiving a high-fat diet. the aim of this study is to examine the effects of chronic t2 administration on basal metabolic rate and body weight in humans. two euthyroid subjects volunteered to undergo t2 administration. body weight, body mass index, blood pressure, heart rate, electrocardiogram, thyroid and liver ultrasonography, glycemia, total cholest ... | 2011 | 22217997 |
| Thoracoscopic excision of the sympathetic chain: an easy and effective treatment for hyperhidrosis in children. | BACKGROUND: Thoracoscopic sympathectomy (TS) is an effective treatment for hyperhidrosis. Various surgical approaches are described in the literature. We describe the technique of thoracoscopic excision of the sympathetic chain done exclusively in children younger than 13 years. METHODS: All patients younger than 13 years who underwent TS from 2006 at a single institution were prospectively identified and fully e ... | 2011 | 21960313 |
| Chemoradiation for patients with large-volume laryngeal cancers. | BACKGROUND: Patients with T4 laryngeal cancers, including those with large-volume (cartilage or tongue-base invasion) lesions, are often excluded from organ-preservation trials due to expectations of inferior outcome in terms of survival and function. We hypothesize that such patients indeed have acceptable survival and function when treated with organ-preservation strategies. METHODS: Retrospective analysis of prospectively collected data of a cohort of patients with T4 laryngeal cancer was car ... | 2011 | 22052816 |
| A homing endonuclease and the 50-nt ribosomal bypass sequence of phage T4 constitute a mobile DNA cassette. | Since its initial description more than two decades ago, the ribosome bypass (or "hop") sequence of phage T4 stands out as a uniquely extreme example of programmed translational frameshifting. The gene for a DNA topoisomerase subunit of T4 has been split by a 1-kb insertion into two genes that retain topoisomerase function. A second 50-nt insertion, beginning with an in-phase stop codon, is inserted near the start of the newly created downstream gene 60. Instead of terminating at this stop codon ... | 2011 | 21930924 |
| Activity of some physiological modulators in reducing the side effects of levothyroxine in patients suffering from primary hypothyroidism. | The use of L-T4 (levothyroxine) in the treatment of primary hypothyroidism causes oxidative stress (OS) and daily discomfort. It is believed that the use of physiological modulators (PMs) may make the treatment more tolerable. | 2011 | 22108485 |
| Diffusion of bacteriophages through artificial biofilm models. | The simple two-chamber diffusion method was improved to study the diffusion properties of bacteriophage (phage) T4 through a model biofilm agarose gel membrane (AGM) embedded with dead host Escherichia coli K12 cells. The apparent diffusion coefficient (D(app) ) of phage T4 was calculated to be 2.4 × 10(-12) m(2) /s in 0.5% AGM, which was lower than the coefficient of 4.2 × 10(-12) m(2) /s in 0.5% AGM without host cells. The phage adsorption process by dead host cells slowed the apparent phage ... | 2011 | 22058083 |
| Ferrocene-functionalized SWCNT for electrochemical detection of T4 polynucleotide kinase activity. | A novel electrochemical strategy for monitoring the activity and inhibition of T4 polynucleotide kinase (PNK) is developed by use of titanium ion (Ti(4+)) mediated signal transition coupled with signal amplification of single wall carbon nanotubes (SWCNTs). In this method, a DNA containing 5'-hydroxyl group is self-assembled onto the gold electrode and used as substrate for PNK. The biofunctionalized SWCNTs with anchor DNA and ferrocene are chosen as the signal indicator by virtue of the intrins ... | 2011 | 22209074 |
| transgenic rice plants harboring the grain hardness-locus region of aegilops tauschii. | grain hardness of wheat is determined by the hardness (ha)-locus region, which contains three friabilin-related genes: puroindoline-a (pina), puroindoline-b (pinb) and gsp-1. in our previous study, we produced the transgenic rice plants harboring the large genomic fragment of the ha-locus region of aegilops tauschii containing pina and gsp-1 genes by agrobacterium-mediated transformation. to examine the effects of the transgenes in the rice endosperms, we firstly confirmed the homozygosity of th ... | 2011 | 21850595 |
| Early pospartum alexithymia and risk for depression: Relationship with serum thyrotropin, free thyroid hormones and thyroid autoantibodies. | Most psychometric evaluations in the postpartum (PP) target depression (PPD) and show an association with thyroid autoantibodies (TAb), not with thyroid function. Three studies evaluated PP alexithymia, but none its relationship with thyroid indices. We tested 74 women aged 31.8±4.64 years, on day 3 PP, by the Edinburgh Postnatal Depression Scale (EPDS), the Montgomery and Asberg Depression Rating Scale (MADRS), and the Toronto Alexithymia Scale (TAS). Concurrently, we measured serum thyrotropin ... | 2011 | 22047958 |
| validation of the 2009 tnm classification for renal cell carcinoma: comparison with the 2002 tnm classification by concordance index. | to assess the validity of the 2009 tnm classification for renal cell carcinoma (rcc) and compare its ability to predict survival relative to the 2002 classification. | 2011 | 21927698 |
| Real-time PCR for the detection of precise transgene copy number in durum wheat. | Recent results obtained in various crops indicate that real-time PCR could be a powerful tool for the detection and characterization of transgene locus structures. The determination of transgenic locus number through real-time PCR overcomes the problems linked to phenotypic segregation analysis (i.e. lack of detectable expression even when the transgenes are present) and can analyse hundreds of samples in a day, making it an efficient method for estimating gene copy number. Despite these advanta ... | 2011 | 21922222 |
| P-selectin, E-selectin, and CD40L over time in chronic hemodialysis patients. | The aim of this study was to measure P-selectin, E-selectin, and CD-4L levels over time in chronic hemodialysis (HD) patients. Thirty stable patients with end-stage renal failure undergoing chronic HD were included in the study. Blood samples were obtained before HD for measurement of P-selectin, E-selectin, and CD-40L. Measurements were performed at month 0 (T0), 3 (T2), 8 (T3), and 13 (T4). The levels of P-selectin, E-selectin, and CD40L were also analyzed according to the occurrence of cardio ... | 2011 | 22099468 |
| in vivo delivery of nucleic acids via glycopolymer vehicles affords therapeutic infarct size reduction in vivo. | using a new class of nontoxic and degradable glycopolymer-based vehicles termed poly(glycoamidoamine)s, we demonstrate virus-like delivery efficacy of oligodeoxynucleotide (odn) decoys to cardiomyoblasts (h9c2), primary cardiomyocytes, and the mouse heart. these glycopolymers bind and compact odn decoys into nanoparticle complexes that are internalized by the cell membrane and mediate nuclear uptake of dna in 90+% of cultured primary cardiomyocytes and 87% of the mouse myocardium. experimental r ... | 2011 | 22186793 |
| [Effects of incretion hormones on growth pituitary adenoma ectomy and evaluation of long-term therapeutic efficacy]. | To investigate the effect of incretion hormones on growth pituitary adenoma ectomy patients and evaluate its long-term therapeutic efficacy. | 2011 | 22094038 |
| Significance of histological prostatitis in patients with urinary retention and underlying benign prostatic hyperplasia or adenocarcinoma of the prostate. | What's known on the subject? and What does the study add? It is known that histological prostatitis is associated with a significantly higher risk for acute urinary retention in men with BPH. This study showed that, in men with BPH, histological prostatitis was associated with urinary retention at a significantly younger age and with higher serum PSA levels. In men with ACP, histological prostatitis was associated with urinary retention at an earlier stage of cancer. Study Type - Prognosis (indi ... | 2011 | 21851551 |
| Postmenopausal women with osteoporosis and musculoskeletal status: a comparative cross-sectional study. | With increased life expectancy of the world's population that has taken place in recent decades, there has been growth in the incidence of illnesses of the most advanced ages, including osteoporosis. However, changes in musculoskeletal disorders are not yet so clear. This study proposes to evaluate musculoskeletal alterations in osteoporotic postmenopausal women and healthy and correlate with bone mineral density of the lumbar spine. | 2011 | 22121400 |
| The effect of the intravenous phenylephrine on the level of spinal anesthesia. | Spinal anesthesia causes hypotension and bradycardia due to sympathetic nerve block and it is difficult to predict the level of sensory block and the duration of blockade. Recent studies have reported that intravenous phenylephrine can reduce the rostral spread of spinal anesthesia in pregnant women. We think a phenylephrine infusion will be useful for maintaining the baseline blood pressure by reducing the rostral spread of spinal anesthesia during the elective surgery of non-obstetric patients ... | 2011 | 22148084 |
| rapid genetic characterization of a novel enterobacteria phage and determination of its host recognizing genes. | we isolated a novel enterobacteria phage ime08 from hospital sewage, then confirmed it was a double-stranded dna phage by digesting its genetic material with dnase i, rnase a and several restriction endonucleases respectively. blast results of random fragments generated by a random pcr cloning method revealed that it belonged to t4-like virus. we subsequently determined the host recognizing genes (g37 and g38) sequence with a pcr-based "genome jumping" protocol based on highly conserved region a ... | 2011 | 22034817 |
| rubinstein-taybi syndrome with scoliosis. | abstract: | 2011 | 21961764 |
| Expression of programmed cell death protein 4 (PDCD4) and miR-21 in urothelial carcinoma. | BACKGROUND: We investigated the role of the programmed cell death 4 (PDCD4) tumor suppressor gene in specimens of transitional cell carcinoma and of healthy individuals. METHODS: PDCD4 immunohistochemical expression was investigated in 294 cases in histologically proven transitional cell carcinoma in different tumorous stages (28 controls, 122 non-muscle invasive urothelial carcinoma, stages Tis-T1, 119 invasive transitional cell carcinoma stages T2-T4 and 25 metastases). MiR-21 expression, an i ... | 2011 | 22133680 |
| aluminium effects on thyroid gland function: iodide uptake, hormone biosynthesis and secretion. | the effects of aluminium (al) on thyroid function were evaluated in adult wistar rats intraperitoneally (i.p) injected with 7 mg al (as lactate)/kg body weight (b.w) per day during a six week period. the time-course kinetics of na(125)i (3 μci per 100 g b.w, i.p) was analysed by measuring gamma-radioactivity of thyroid, serum, serum protein precipitate and bile, at times ranging from 2 to 96 h post-dosing. in al-treated group the (125)i(-) thyroid uptake at 24 h (15,840 ± 570 vs. 18,030 ± 630 dp ... | 2011 | 22099156 |
| neuropsychological function in patients who have had epilepsy surgery: a long-term follow-up. | we examined the relationship between seizure outcomes and long-term changes in memory and intellectual function in 70 patients who had undergone temporal lobe resection for medically intractable epilepsy. patients were assessed on four occasions: preoperatively (t1), 3months postoperatively (t2), 1year postoperatively (t3), and more than 5years postoperatively (t4). the majority of patients had stable memory function across the assessments. however, many were functioning below the 15th percentil ... | 2011 | 22100066 |
| [Resistant ovary syndrome. Case report]. | Patients with primary amenorrhea, sexual infantilism and elevated pituitary gonadotropins are frequently diagnosed with hypogonadism hypergonadotropic and suspected ovarian failure, secondary to a chromosomal abnormality, intrinsic ovarian failure or altered receptors for gonadotropins, mainly FSH (ovarian resistance). We report the case of a 16-year-old, admitted to the endocrinology clinic for primary amenorrhea and lack of development of secondary sexual characteristics. A complete physical e ... | 2011 | 21966839 |
| labelled antibody-based one-step time-resolved fluoroimmunoassay for measurement of free thyroxine in serum. | valid assays measuring free thyroxine (ft4) must perform without bias despite large variations in the concentrations and affinities of serum thyroxine-binding proteins in the population. we developed a new, rapid one-step labelled-antibody time-resolved fluoroimmunoassay (trfia) for ft4. | 2011 | 21885471 |
| presence of free cancer cells in the peritoneal cavity of patients who underwent curative gastrectomy with lymph node dissection. | background/aims: the aim of this study was to determine the ratio of patients with positive peritoneal cytology who underwent radical gastrectomy for gastric cancer, to evaluate the factors effecting risk of positive cytology and to analyze the effects cytology findings on survival. methodology: peritoneal lavage samples were obtained from 255 patients who underwent radical gastrectomy with d2 (184 patients) or d3 (71 patients) lymph node dissection between january 2000 and december 2007. result ... | 2011 | 22155861 |
| comparison of treatment results between surgery alone, preoperative short-course radiotherapy, or long-course concurrent chemoradiotherapy in locally advanced rectal cancer. | background: the aim of this study is to compare the results between surgery alone, preoperative radiotherapy (rt), or preoperative concurrent chemoradiotherapy (ccrt) followed by surgery in the treatment of locally advanced rectal cancer in asian patients. methods: this study included 151 consecutive patients with clinical t3, t4 or node-positive rectal cancer from jan. 2005 to dec. 2007. eighty-six patients underwent total mesorectal excision (tme) alone, 28 patients received preoperative rt (2 ... | 2011 | 21938495 |
| [influence of acupuncture of zusanli (st 36) on connectivity of brain functional network in healthy subjects]. | to observe the effect of acupuncture of zusanli (st 36) on electroencephalogram (eeg) so as to probe into its law in regulating the interconnectivity of brain functional network. | 2011 | 21942182 |
| towards a structural comprehension of bacterial type vi secretion systems: characterization of the tssj-tssm complex of an escherichia coli pathovar. | type vi secretion systems (t6ss) are trans-envelope machines dedicated to the secretion of virulence factors into eukaryotic or prokaryotic cells, therefore required for pathogenesis and/or for competition towards neighboring bacteria. the t6ss apparatus resembles the injection device of bacteriophage t4, and is anchored to the cell envelope through a membrane complex. this membrane complex is composed of the tssl, tssm and tagl inner membrane anchored proteins and of the tssj outer membrane lip ... | 2011 | 22102820 |
| phase ii trial of preoperative paclitaxel, gemcitabine, and trastuzumab combination therapy in her2 positive stage ii/iii breast cancer: the korean cancer study group br 07-01. | an addition of trastuzumab preoperatively to chemotherapy for human epidermal growth factor receptor 2 (her2) positive breast cancer improved relapse-free survival (rfs). this study was designed to evaluate the efficacy and safety of preoperative paclitaxel, gemcitabine, and trastuzumab (pgh) combination for her2-positive breast caner. pathologically, proven node positive stage ii/iii breast cancer patients with adequate organ function and no history of anti-cancer therapy were eligible. patient ... | 2011 | 22094934 |
| prognostic value of prevertebral space involvement in nasopharyngeal carcinoma based on intensity-modulated radiotherapy. | purpose: to investigate the prognostic significance of prevertebral space involvement (psi) in patients with nasopharyngeal carcinoma (npc) treated with intensity-modulated radiotherapy (imrt). methods and materials: a retrospective review of data from 506 biopsy-proven, nonmetastatic npcs was performed. patients underwent magnetic resonance imaging examinations and received imrt as their primary treatment. results: in this series, 161 npc patients (31.8%) had psi. parapharyngeal space (p < 0.00 ... | 2011 | 21864993 |
| laminectomy, durotomy, and piotomy effects on spinal cord intramedullary pressure in severe cervical and thoracic kyphotic deformity: a cadaveric study. | object previous studies have shown that cervical and thoracic kyphotic deformity increases spinal cord intramedullary pressure (imp). using a cadaveric model, the authors investigated whether posterior decompression can adequately decrease elevated imp in severe cervical and thoracic kyphotic deformities. methods using an established cadaveric model, a kyphotic deformity was created in 16 fresh human cadavers (8 cervical and 8 thoracic). a single-level rostral laminotomy and durotomy we ... | 2011 | 22077470 |
| The Evolution of Thyroid Function with Puberty. | Objective: This study was planned to describe thyroid functional status in different stages of puberty. Study design: We collected data from 5 schools across different geographical zones of Delhi. All children who consented were evaluated for anthropometry, pubertal stage, goitre status, serum free T3 (FT3), free T4 (FT4), TSH, anti-TPO (thyroid peroxidase) antibodies and thyroid ultrasound. From this sample, a disease- and risk-free or "reference population" was obtained by excluding those wi ... | 2011 | 22171622 |
| structure and function of the small terminase component of the dna packaging machine in t4-like bacteriophages. | tailed dna bacteriophages assemble empty procapsids that are subsequently filled with the viral genome by means of a dna packaging machine situated at a special fivefold vertex. the packaging machine consists of a "small terminase" and a "large terminase" component. one of the functions of the small terminase is to initiate packaging of the viral genome, whereas the large terminase is responsible for the atp-powered translocation of dna. the small terminase subunit has three domains, an n-termin ... | 2011 | 22207623 |
| an exploratory study of the influence of clinico-demographic variables on swallowing and swallowing-related quality of life in a cohort of oral and oropharyngeal cancer patients treated with primary surgery. | there are insufficient data on swallowing and the consequences of its dysfunction in patients with cancers of the oral cavity (oc) and oropharynx (op) that are treated with primary surgery. the study attempts to explore the effect of important clinico-demographic variables on post-treatment swallowing and related quality of life (qol) in post-surgical oc and op cancer patients. sixty-two consecutive oc and op cancer patients completed the md anderson dysphagia inventory (mdadi) questionnaire. me ... | 2011 | 21909656 |
| comparative study of perdialytic volemia variability in chronic dialysis patients between acetate- free biofiltration and bicarbonate hemodialysis. | we have developed since 1994 a new hemodialysis (hd) technique called acetate biofiltration 84% (afb 84%) that is characterized by the absence of acetate in the dialysate and the complete correction of buffer balance by post- dilutional infusion of bicarbonate- based replacement solution. our study aimed to compare the variability of perdialytic volemia [net ultrafiltration (uf) rate, total uf, δweight (t4- t0)] during afb 84% and bicarbonate dialysis (bd) for stable chronic hemodynamic patients ... | 2011 | 21912029 |
| a missed injury leading to delayed diagnosis and postoperative infection of an unstable thoracic spine fracture - case report of a potentially preventable complication. | abstract: | 2011 | 21999783 |
| the effect of nitroglycerin on hemodynamic changes during laparoscopic low anterior resection. | more laparoscopic low anterior resections (lar) are being performed in recent years. there has been controversy around the hemodynamic changes affected by the trendelenburg position and pneumoperitoneum during lar. the goal of this study was to analyze the effect of nitroglycerin (ntg) on hemodynamic changes during lar. | 2011 | 22148087 |
| human equilibrative nucleoside transporter 1 expression is a strong independent prognostic factor in uicc t3-t4 pancreatic cancer patients treated with preoperative gemcitabine-based chemoradiotherapy. | background/purpose: we aimed to determine the relationship between the intratumoral expression of human equilibrative nucleoside transporter (hent1), the main gemcitabine transporter into cells, and the outcome of gemcitabine-based chemoradiotherapy (gem-crt) in patients with international union against cancer (uicc) t3-t4 pancreatic adenocarcinoma. methods: the expressions of hent1, thymidylate synthase (ts), and dihydropyrimidine dehydrogenase were immunohistochemically analyzed using the rese ... | 2011 | 21898089 |
| An investigation on different harvesting methods on young pods of KKU # 922 maize (Zea mays L.) cultivar for baby corn production. | This study aimed to search for the best indicator to be used for the harvest of maize pods for baby corn production. A Randomized Complete Block Design (RCBD) with four replications was used. The treatments are: T1 (Control) Taking sample when silks of female flower had extended from tip of pod up to 3 cm long T2, silks had extended 1 cm long T3, silks had extended 2 cm long T4, blooming of female flower for 2 days T5, blooming of female flowers for 4 days T6, blooming of female flower for 6 day ... | 2011 | 21902059 |
| Outcome of T4 (International Union Against Cancer Staging System, 7th edition) or Recurrent Nasal Cavity and Paranasal Sinus Carcinoma Treated with Proton Beam. | PURPOSE: To investigate the clinical features, prognostic factors, and toxicity of treatment for unresectable carcinomas of the nasal cavity and paranasal sinus (NCPS) treated with proton beam therapy (PBT). METHODS AND MATERIALS: Seventeen patients (13 men, 4 women) with unresectable carcinomas of the NCPS who underwent PBT at the University of Tsukuba between 2001 and 2007 were analyzed. The patients' median age was 62 years (range, 30-83 years). The tumors were located in the nasal cavity in ... | 2011 | 22099036 |
| Idiopathic spinal cord herniation at two separate zones of the thoracic spine: the first reported case and literature review. | Idiopathic spinal cord herniation (ISCH) is a rare cause of progressive myelopathy. Preoperative diagnosis can be made with magnetic resonance imaging (MRI). Many surgical techniques have been applied by various authors, and ISCH is usually reversible by surgical treatment. | 2011 | 21862417 |
| Does the baricity of bupivacaine influence intrathecal spread in the prolonged sitting position before elective cesarean delivery? A prospective randomized controlled study. | Difficulties in inserting an epidural catheter while performing combined spinal-epidural anesthesia for cesarean delivery may lead to undue delays between the spinal injection of the local anesthetic mixture and the adoption of the supine position with lateral tilt. We hypothesized that this delay may affect the intrathecal distribution of local anesthetic of different baricities such that hypobaric local anesthetic would lead to a higher sensory block level. | 2011 | 21890887 |
| target highlights in casp9: experimental target structures for the critical assessment of techniques for protein structure prediction. | one goal of the casp community wide experiment on the critical assessment of techniques for protein structure prediction is to identify the current state of the art in protein structure prediction and modeling. a fundamental principle of casp is blind prediction on a set of relevant protein targets, that is, the participating computational methods are tested on a common set of experimental target proteins, for which the experimental structures are not known at the time of modeling. therefore, th ... | 2011 | 22020785 |
| ct thoracic duct lymphography in cats by popliteal lymph node iohexol injection. | three different doses (1.0, 1.5, and 2.0 ml) of iohexol (300 mgi/ml) were injected percutaneously into the popliteal lymph node of eight adult cats under ultrasound guidance. serial transverse ct images of five regions of interest (l3, t13, t8, t4, and t1 level) were performed at 2-min intervals, and the attenuation in hounsfield units (hu) of the lymphatic vessels was measured for determination of the optimal dose of iohexol and ct scan parameters. the optimal dose was 1.5 ml and helical ct acq ... | 2011 | 22136199 |