Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| doubling the dose of clopidogrel restores the loss of antiplatelet effect induced by esomeprazole. | introduction: concerns have been raised about the potential adverse interaction between clopidogrel and ppis. we studied the impact of esomeprazole and ranitidine on the antiplatelet action of clopidogrel and aspirin and sought to determine whether doubling the dose of clopidogrel could restore its efficacy. materials and methods: in a randomized prospective crossover study, we tested platelet reactivity to aspirin and clopidogrel (75 and 150mg) with and without esomeprazole or ranitidine using ... | 2011 | 21777954 |
| cultural rationales guiding medication adherence among african american with hiv/aids. | abstract to date, only modest gains have been achieved in explaining adherence to medical regimens, limiting effective interventions. this is a particularly important issue for african americans who are disproportionately affected by the hiv epidemic. few studies have focused on intragroup variation among african americans in adherence to art. the aim of this study was to identify and describe the cultural rationales guiding african american patients' formulation and evaluation of adherence. rat ... | 2011 | 21777141 |
| twenty-year experience in the management of squamous cell anal canal carcinoma with interstitial brachytherapy. | objectives the aim of this study was to retrospectively evaluate clinical characteristics, local control, acute and late toxicity, and prognostic factors of patients with anal canal carcinoma treated with brachytherapy. methods from 1989 to 2009, 38 patients were treated with iridium 192 low-dose-rate (n=26) or pulsed-dose-rate (n=12) interstitial brachytherapy at a single institution. the median age was 62 years (range, 38-86 years). the tnm classification was as follows: 10 t1, 22 t2, 5 t3 and ... | 2011 | 21775274 |
| radiation therapy oncology group 0247: a randomized phase ii study of neoadjuvant capecitabine and irinotecan or capecitabine and oxaliplatin with concurrent radiotherapy for patients with locally advanced rectal cancer. | purpose: to evaluate the rate of pathologic complete response (pcr) and the toxicity of two neoadjuvant chemoradiotherapy (chemort) regimens for stage t3-t4 rectal cancer in a randomized phase ii study. methods and materials: patients with stage t3 or t4 rectal cancer of <12 cm from the anal verge were randomized to preoperative rt (50.4 gy in 1.8-gy fractions) with concurrent capecitabine (1,200 mg/m(2)/d mondays through friday) and irinotecan (50 mg/m(2) weekly in four doses) (arm 1) or concur ... | 2011 | 21775070 |
| concurrent superselective intra-arterial chemotherapy and radiotherapy for late-stage squamous cell carcinoma of the temporal bone. | this study evaluated the efficacy of concurrent superselective intra-arterial chemotherapy and radiotherapy without surgery for late-stage squamous cell carcinoma of the temporal bone, which typically has a poor prognosis. | 2011 | 21774443 |
| prognostic and risk factors in patients with locally advanced cutaneous squamous cell carcinoma of the trunk and extremities. | 55 patients with advanced cutaneous squamous cell carcinoma (cscc) of the trunk and extremities were studied. a tissue microarray was constructed using immunohistochemistry to quantify expression of the her family, e-cadherins, and podoplanin. clinical and histopathological factors related to lymph node metastasis and prognosis were also established. primary tumor positivity was 25.5% for egfr, 87.3% for her-3, and 48.1% for her-4. metastases were positive for egfr in 41.7%, for her-3 in 83.3%, ... | 2011 | 21773035 |
| the ftsz gene of mycobacterium smegmatis is expressed through multiple transcripts. | the principal essential bacterial cell division gene ftsz is differentially expressed through multiple transcripts in diverse genera of bacteria in order to meet cell division requirements in compliance with the physiological niche of the organism under different environmental conditions. we initiated transcriptional analyses of ftsz gene of the fast growing saprophytic mycobacterium, mycobacterium smegmatis, as the first step towards understanding the requirements for ftsz for cell division und ... | 2011 | 21772930 |
| central npy-y5 receptors activation plays a major role in fasting-induced pituitary-thyroid axis suppression in adult rat. | neuropeptide y (npy) inhibits trh neurons in fed state, and hypothalamic npy higher expression during fasting has been proposed to be involved in fasting-induced suppression of the hypothalamus-pituitary-thyroid (hpt) axis. we investigated the role of central y5 receptors in the control of thyrotropin (tsh) and thyroid hormone (th) secretion. fed and fasting rats received twice daily central injections (3rd ventricle) of y5 receptor antagonist (cgp71683; 15nmol/rat) for 72h. fasted rats also rec ... | 2011 | 21771616 |
| lectin domains of polypeptide galnac-transferases exhibit glycopeptide binding specificity. | udp-galnac:polypeptide alpha-n-acetylgalactosaminyltransferases (galnac-ts) constitute a family of up to 20 transferases that initiate mucin-type o-glycosylation. the transferases are structurally composed of catalytic and lectin domains. two modes have been identified for the selection of glycosylation sites by galnac-ts: confined sequence recognition by the catalytic domain alone, and concerted recognition of acceptor sites and adjacent galnac-glycosylated sites by the catalytic and lectin dom ... | 2011 | 21768105 |
| should we treat mild subclinical/mild hyperthyroidism? no. | the management of a patient with subclinical hyperthyroidism or mild thyroid over-activity is controversial. subclinical hyperthyroidism is defined as a serum thyrotrophin (tsh) below the reference range but a normal thyroxine (t(4)) and triiodothyronine (t(3)) level in a patient who is either asymptomatic or has only non-specific symptoms. epidemiological studies report an overall prevalence of approximately 3%, with men and women over 65years and those in iodine deficient regions having the hi ... | 2011 | 21767747 |
| acute evaluation of pituitary function in patients with crimean congo haemorrhagic fever. | context: crimean congo haemorrhagic fever (cchf) can cause a fatal haemorrhagic syndrome. pituitary ischaemia/infarction and necrosis are known causes of hypopituitarism, often remaining unrecognized due to subtle clinical manifestations. objective: our aim was to evaluate the effect of cchf on pituitary function. subject and methods: levels of serum free t3, free t4, tsh, gh, igf-i, prolactin, cortisol, testosterone (in males) and oestrogen (in females) were studied in 20 patients who had be ... | 2011 | 21767285 |
| antenatal maternal antidepressants drugs affect activin a concentrations in maternal blood, in amniotic fluid and in fetal cord blood. | abstract objective. the use of antidepressant drugs during pregnancy is rapidly increasing both in europe and in the usa, with controversial data regarding side-effects on fetus and newborn. we investigated, in pregnant women and in fetal biological fluids whether the concentrations of a brain protein, activin a, changed in association with the use of selective serotonin re-uptake inhibitors (ssri). methods. we conducted a case control study in 24 women treated with ssris, matched with 24 health ... | 2011 | 21767104 |
| efficacy, safety and prognostic features of resected colon carcinoma treated in "real world" practice: a retrospective cohort-study. | treatment outcomes and prognostic features of a specific cancer generally come from prospective randomized studies. it seems reasonable to ask the question whether the results of prospective randomized studies entirely reflect the results of the population treated in "real world" practice. therefore we performed a retrospective cohort analysis in order to find out the efficacy of adjuvant chemotherapy as well as the prognostic factors of our patient population treated in daily practice, and comp ... | 2011 | 21766495 |
| the effect of lead acetate toxicity on experimental male albino rat. | the toxic effect of pb ion (lead acetate) was investigated using male albino rats, which was ingested at 1/20, 1/40, and 1/60 sublethal doses. relative to normal control, the ingestion of pb(2+) induced significant stimulation in alt and ast activity. in addition, total soluble protein and albumin contents of plasma were decreased, while the content of globulin was changed by the pb(2+) treatments. the cholinesterase activity was inhibited, but the activities of alkaline and acid phosphates as w ... | 2011 | 21766233 |
| effects of supraphysiological doses of levothyroxine on sleep in healthy subjects: a prospective polysomnography study. | disrupted sleep is prevalent in both mood and thyroid disorders. given the emerging use of thyroid hormones in the treatment of mood disorders, we investigated the effects of supraphysiological doses of levothyroxine (l-t4) on sleep. in an open-label design, 13 healthy subjects received up to 500?µg/day for an eight-week period. a baseline night was polysomnographically recorded (psg) followed by psg under the maximum tolerated dose of l-t4. all subjects developed hyperthyroxinemia. the heart ra ... | 2011 | 21765990 |
| the role of hypothalamic tri-iodothyronine availability in seasonal regulation of energy balance and body weight. | seasonal cycles of body weight provide a natural model system to understand the central control of energy balance. studies of such cycles in siberian hamsters suggest that a change in the hypothalamic availability of thyroid hormone is the key determinant of annual weight regulation. uptake of thyroid hormone into the hypothalamus from the peripheral circulation occurs largely through a specific monocarboxylate transporter expressed by tanycyte cells lining the third ventricle. tanycytes are the ... | 2011 | 21765988 |
| thyroid hormone action in cerebellum and cerebral cortex development. | thyroid hormones (th, including the prohormone thyroxine (t4) and its active deiodinated derivative 3,3',5-triiodo-l-thyronine (t3)) are important regulators of vertebrates neurodevelopment. specific transporters and deiodinases are required to ensure t3 access to the developing brain. t3 activates a number of differentiation processes in neuronal and glial cell types by binding to nuclear receptors, acting directly on transcription. only few t3 target genes are currently known. deeper investiga ... | 2011 | 21765985 |
| stereotactic radiosurgery in combination with chemotherapy as primary treatment for head and neck cancer. | purpose: the purpose of this study was to investigate the effect of stereotactic radiosurgery on local control and organ preservation in cases of primary head and neck cancer. patients and methods: in this retrospective study, 14 patients with a mean age of 73 years were treated between march 2006 and september 2007 with stereotactic radiosurgery for the management of primary head and neck cancer. the patients had biopsy confirmation of disease before treatment and all patients were confirmed wi ... | 2011 | 21764492 |
| the significance of abdominal para-aortic lymph node metastasis in patients with lower thoracic esophageal cancer. | para-aortic lymph node (paln) recurrence is often seen in patients with lower thoracic esophageal cancer treated by esophagectomy with extended lymph node dissection. however, the clinicopathological characteristics of patients with paln metastasis and the significance of paln dissection are unknown. a total of 283 patients with lower thoracic esophageal cancer underwent esophagectomy with lymphadenectomy at our hospital between april 1984 and march 2007. among these 283 patients, 60 patients we ... | 2011 | 21762280 |
| radiotherapy may improve overall survival of patients with t3/t4 transitional cell carcinoma of the renal pelvis or ureter and delay bladder tumour relapse. | abstract: background: since transitional cell carcinoma (tcc) of the upper urinary tract is a relatively uncommon malignancy, the role of adjuvant radiotherapy is unknown. methods: we treated 133 patients with tcc of the renal pelvis or ureter at our institution between 1998 and 2008. the 67 patients who received external beam radiotherapy (ebrt) following surgery were assigned to the radiation group (rt). the clinical target volume included the renal fossa, the course of the ureter to the entir ... | 2011 | 21756352 |
| comparison of clinical and surgical-pathological staging in iiia non-small cell lung cancer patients. | background: the heterogeneous group of iiia nsclc patients requires careful preoperative clinical staging as tumor size and lymph node involvement guide treatment. the purpose of our study was to analyze the correctness of clinical staging in iiia patients. methods: retrospective analysis of all patients resected due to lung cancer that had been staged iiia either clinically using invasive and noninvasive techniques or surgical-pathologically after surgical resection. correctness, sensitivity, s ... | 2011 | 21755379 |
| staging and grading as prognostic factors in maxillary squamous cell carcinoma. | purpose: this retrospective study was performed to present our long-term results in the treatment of maxillary squamous cell carcinoma and evaluate especially the influence of t staging and grading on patients' survival. patients and methods: we performed a retrospective analysis of 93 consecutive patients with alveolar, gingival, or palatal maxillary scc treated at our clinic with surgical resection and/or radiation therapy. data were obtained from chart review and patients' records and were an ... | 2011 | 21752505 |
| mass spectrometric immunoassay for quantitative determination of transthyretin and its variants. | transthyretin (ttr, or prealbumin) is a tetrameric protein found in plasma and cerebrospinal fluid. its major role is to transport thyroid hormones (thyroxin-t4) and retinol (through association with retinol-binding protein). ttr has been studied extensively, due to the great number of point mutations that result in sequence heterogeneity. many of these variants are associated with pathological conditions that result in extracellular deposition of amyloid fibers in tissues. in this work, we have ... | 2011 | 21751365 |
| relationship between urinary phthalate and bisphenol a concentrations and serum thyroid measures in u.s. adults and adolescents from nhanes 2007-08. | background: limited animal, in vitro, and human studies have reported that exposure to phthalates or bisphenol a (bpa) may impact thyroid signaling. objective: explore the cross-sectional relationship between urinary concentrations of metabolites of di(2-ethylhexyl) phthalate (dehp), dibutyl phthalate (dbp), and bpa with a panel of serum thyroid measures among a representative sample of u.s. adults and adolescents. methods: data on urinary biomarkers of exposure to phthalates and bpa, serum thyr ... | 2011 | 21749963 |
| diagnostic significance of magnetic resonance imaging in preoperative evaluation of patients with laryngeal tumors. | to evaluate the diagnostic accuracy of pretreatment surgical magnetic resonance images (mri) in the assessment of patients with laryngeal tumors. the prospective study included 34 patients (mean age 62.2 ± 5.1 years) with suspected tumors of the larynx who underwent laryngeal endoscopy, followed by mri. the mri images were evaluated for the invasion of anterior commissure, subglottis, paraglottic and preepiglotic space, cartilage invasion, extension to extralaryngeal tissue and lymph nodes, and ... | 2011 | 21748653 |
| association between vitiligo and thyroid autoimmunity. | background. vitiligo is a common skin disorder characterized by macular depigmentation of the skin. the etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity and endocrine disfunction may be involved. objective. the aim of this study was to determine whether vitiligo is statistically associated with thyroid autoimmunity. method. in a prospective case-control study, we compared the frequency of thyroid autoantibodies (thyroglobulin antibody, anti-tg and thyroid ... | 2011 | 21747969 |
| speech impairment in primary hypothyroidism. | thyroid hormone deficiency may affect human speech and voice. the aim of this study was to evaluate speech variables in patients with hypothyroidism. | 2011 | 21747217 |
| the gp38 adhesins of the t4 superfamily: a complex modular determinant of the phage's host specificity. | the tail fiber adhesins are the primary determinants of host range in the t4-type bacteriophages. among the indispensable virion components, the sequences of the long tail fiber (ltf) genes and their associated adhesins are among the most variable. the predominant form of the adhesin in the t4-type phages is not even the version of the gene encoded by t4, the archetype of the superfamily, but rather a small unrelated protein (gp38) encoded by closely related phages such as t2 and t6. this gp38 a ... | 2011 | 21746838 |
| impact of flavonoids on thyroid function. | flavonoids are polyphenolic compounds of natural occurrence produced by plants that are largely consumed both for therapeutic purposes and as food. experimental data have shown that many flavonoids could inhibit thyroperoxidase activity, decreasing thyroid hormones levels thus increasing tsh and causing goiter. in humans, infants fed with soy formula have been shown to develop goiter. however, in post-menopausal women soy intake did not affect thyroid function. in thyroid tumor cell line, flavon ... | 2011 | 21745527 |
| protein profiling of angiogenesis-related growth factors in laryngeal carcinoma: pattern of protein expression in relation to tumour progression. | the expression of angiogenesis-related proteins was determined in laryngeal tumour tissue, associated tumour involved lymph nodes, apparently normal mucosa and control tissue and were related to tumour stage. both laryngeal tumour tissue and associated metastatic nodes were obtained from seven patients undergoing surgical resection; in four cases apparently normal mucosa was also dissected from the tumour specimen margins. control uvula mucosa was obtained from five healthy volunteers undergoing ... | 2011 | 21743965 |
| impact of evidence-based clinical guidelines on the adoption of postmastectomy radiation in older women. | background: although postmastectomy radiation therapy (pmrt) improves survival for patients with high-risk breast cancer, previous literature suggested that it is underused. the impact of recent clinical guidelines on pmrt use is unknown. accordingly, the authors used the surveillance, epidemiology, and end results (seer)-medicare cohort to determine whether the use of pmrt has increased in response to evidence-based guidelines. methods: in total, 38,322 women aged ôëñ66 years who underwent mast ... | 2011 | 21710653 |
| exploring the roles of nucleobase desolvation and shape complementarity during the misreplication of o(6)-methylguanine. | o(6)-methylguanine (o(6)-meg) is a miscoding dna lesion arising from the alkylation of guanine. this report uses the bacteriophage t4 dna polymerase as a model to probe the roles of hydrogen-bonding interactions, shape/size, and nucleobase desolvation during the replication of this miscoding lesion. this was accomplished by using transient kinetic techniques to monitor the kinetic parameters for incorporating and extending natural and nonnatural nucleotides. in general, the efficiency of nucleot ... | 2011 | 21819995 |
| associations between polybrominated diphenyl ether (pbde) flame retardants, phenolic metabolites, and thyroid hormones during pregnancy. | background: polybrominated diphenyl ethers (pbdes) are chemical additives used as flame retardants in commercial products. pbdes are bioaccumulative, persistent, and have been linked to several adverse health outcomes. objectives: this study leverages an ongoing pregnancy cohort to measure pbdes, and pbde metabolites, in serum collected from an understudied population of pregnant women late in their third trimester. a secondary objective was to determine if the pbdes, or their metabolites, were ... | 2011 | 21715241 |
| Genome and proteome of Campylobacter jejuni bacteriophage NCTC 12673. | Campylobacter jejuni continues to be the leading cause of bacterial food-borne illness worldwide, so improvements to current methods used for bacterial detection and disease prevention are needed. We describe here the genome and proteome of C. jejuni bacteriophage NCTC 12673 and the exploitation of its receptor-binding protein for specific bacterial detection. Remarkably, the 135-kb Myoviridae genome of NCTC 12673 differs greatly from any other proteobacterial phage genome described (including C ... | 2011 | 21965409 |
| Cord blood levels of thyroid hormones and IGF-1 weakly correlate with breast milk levels of PBDEs in Taiwan. | In vivo studies indicate that prenatal or neonatal exposure of rodents to polybrominated diphenyl ethers (PBDEs) disrupts thyroid hormone balance, but few studies have reported an association of PBDEs and insulin-like growth factor 1 (IGF-1). The goal was to examine whether PBDEs exposure affects the levels of thyroid hormones and IGF-1 in cord blood. Study participants were healthy pregnant women recruited from the general population in central Taiwan between 2000 and 2001 and in southern Taiwa ... | 2011 | 22088798 |
| complete genomic sequence of a t4-like bacteriophage, phias4, infecting aeromonas salmonicida subsp. salmonicida. | a newly identified virulent phage (named phias4) infecting aeromonas salmonicida subsp. salmonicida was isolated from river water in korea. morphological analysis of phias4 by transmission electron microscopy revealed that it belonged to the family myoviridae. the genome of phias4 comprised a linear double-stranded dna of 163,875 bp with a g + c content of 41.3%, and genomic analysis revealed 271 putative orfs, 67 putative promoters, 25 putative terminator regions, and 16 trna-encoding genes. mo ... | 2011 | 22116495 |
| bispectral monitoring in dogs subjected to ovariohysterectomy and anesthetized with halothane, isoflurane or sevoflurane. | to assess the effect of halothane (h), isoflurane (i) or sevoflurane (s) on the bispectral index (bis), and the effect of the addition of meperidine in dogs subjected to ovariohysterectomy. | 2011 | 21831053 |
| Resistant thyrotoxicosis in a patient with graves disease: a case report. | Background. Conventional management of thyrotoxicosis includes antithyroid drugs, radioactive iodine, and surgery while adjunctive treatment includes beta-blockers, corticosteroids, inorganic iodide and iopanoic acid. Very rarely, patients may be resistant to these modalities and require additional management. Case Presentation. A 50-year-old lady presented with weight loss and palpitations diagnosed as atrial fibrillation. Her past history was significant for right thyroid lobectomy for thyroto ... | 2011 | 21845211 |
| vash is a transcriptional regulator of the type vi secretion system functional in endemic and pandemic vibrio cholerae. | the gram-negative bacterium vibrio cholerae is the etiological agent of cholera, a disease characterized by the release of high volumes of watery diarrhea. many medically important proteobacteria, including v. cholerae, carry one or multiple copies of the gene cluster that encodes the bacterial type vi secretion system (t6ss) to confer virulence or interspecies competitiveness. structural similarity and sequence homology between components of the t6ss and the cell-puncturing device of t4 bacteri ... | 2011 | 21949076 |
| Effectiveness and pitfalls of elective neck dissection in N0 laryngeal cancer. | The aim of the study was to evaluate the efficacy and potential pitfalls of selective neck dissection of levels II-IV in controlling occult neck disease in clinically negative neck (cN0) of patients with laryngeal squamous cell carcinoma. Charts of 96 consecutive cN0 laryngeal cancer patients undergoing 122 neck dissections at the University of Florence from January 2000 to December 2004 were reviewed. N0 neck was defined with contrast enhanced computed tomography scan. Occult neck disease rate ... | 2011 | 22058599 |
| Neoadjuvant Chemotherapy in 29 Patients with Locally Advanced Follicular or Hürthle Cell Thyroid Carcinoma: A Phase 2 Study. | Background: It is believed that chemotherapy (ChT) is ineffective in follicular thyroid carcinoma (FTC) and Hürthle cell thyroid carcinoma (HCTC). The aim of our retrospective study was to find out whether neodjuvant ChT before thyroid surgery had any effect on the size of primary tumor in patients with FTC or HCTC. Methods: The study included 29 patients (20 women, 9 men; mean age: 60.8 years) with FTC or HCTC who had T3 or T4 tumor and were treated with neoadjuvant ChT from 1979 to 2004. A m ... | 2011 | 22175241 |
| Geofold: Topology-based protein unfolding pathways capture the effects of engineered disulfides on kinetic stability. | Protein unfolding is modeled as an ensemble of pathways, where each step in each pathway is the addition of one topologically possible conformational degree of freedom. Starting with a known protein structure, GeoFold hierarchically partitions (cuts) the native structure into substructures using revolute joints and translations. The energy of each cut and its activation barrier are calculated using buried solvent accessible surface area, side chain entropy, hydrogen bonding, buried cavities, and ... | 2011 | 22189917 |
| Thrombin generation in severe sepsis. | INTRODUCTION: Hemostasis and inflammation are two tightly interrelated systems in the host's response to infection. Thrombin generation in sepsis plays a crucial role in enhancing and modulation of inflammation. The present study aimed to investigate the course of thrombin generation in patients with severe sepsis, and its correlation with outcome. MATERIALS AND METHODS: Thrombin generation was measured in platelet-poor plasma from 32 healthy controls and 75 patients with severe sepsis using the ... | 2011 | 21872299 |
| Viral Infections in Septic Shock (VISS-Trial)-Crosslinks Between Inflammation and Immunosuppression. | BACKGROUND: Recent investigations provided evidence that herpes simplex virus (HSV-1) and cytomegalovirus (CMV) are reactivated in critically ill individuals. However, at this time, it remains unclear whether these viral infections are of real pathogenetic relevance or represent innocent bystanders. MATERIALS AND METHODS: In total, 60 patients with septic shock were enrolled. Blood samples and tracheal secretion were collected at the time of sepsis diagnosis (T0) as well as 7 d (T1), 14 d (T2), ... | 2011 | 22172138 |
| The incidence of thyroid function abnormalities and natural course of subclinical thyroid disorders, Tehran, I. R. Iran. | Back ground: Despite the high prevalence of thyroid dysfunction, the epidemiology and natural course of these disorders have not yet been identified. Aim: the present survey was conducted to determine the incidence of thyroid dysfunction and natural course of subclinical thyroid disorders in an urban community of Tehran, I. R. Iran. Subjects & Methods: Serum TSH and thyroperoxidase antibody (TPOAb) were measured at baseline and after 6.7 years from a sample of 1999 randomly selected subjects ... | 2011 | 21971483 |
| spinal intradural, extramedullary anaplastic ependymoma with an extradural component: case report and review of the literature. | there have been 18 reported cases of primary spinal intradural, extramedullary ependymomas reported in the literature. one of the 18 cases had an extradural component and was benign. our case is the second spinal intradural, extramedullary ependymoma with an extradural component and the first with its initial presentation as an anaplastic ependymoma. | 2011 | 21918734 |
| treatment with levothyroxine in pregnant rats with subclinical hypothyroidism improves cell migration in the developing brain of the progeny. | aim: this study aims to investigate whether maternal subclinical hypothyroidism (sch) influences the developing brain, and the effect of treatment with levothyroxine in early maternal sch on the progeny's developing brain. material and methods: 75 thyroidectomized female wistar rats were divided randomly into groups of hypothyroidism (ch), sch, sch treated with levothyroxine from embryonic day 10 (e10), e13 and e17 till post-natal day 21. there were 15 sham operated controls. results: pups from ... | 2011 | 22024639 |
| decreased levels of alternative co-stimulatory receptors ox40 and 4-1bb characterise t cells from head and neck cancer patients. | background and aim: head and neck cancers (hnc) are aggressive tumours. tumour-specific t cells are frequently identified in patients with cancer, although they fail to control tumour progression. a family of proteins called co-stimulatory receptors regulate the function of t cells and may account for t cell dysfunction in cancer. our aim was to characterise co-stimulatory receptors on t cells in hnc patients to identify novel targets for immunotherapy. methods: peripheral blood mononuclear cell ... | 2011 | 22204816 |
| expression analysis elucidates the roles of maml1 and twist1 in esophageal squamous cell carcinoma aggressiveness and metastasis. | background: epithelial-mesenchymal transition has recently attracted great attention in studying the malignant progression of cells through a converging pathway of oncogenesis and metastasis. twist1 and mastermind-like 1 (maml1) are major regulators of emt through different pathways. the aim of this study was to investigate the clinicopathological relevance of the expression of maml-1 and twist1 genes in esophageal squamous cell carcinoma (escc). ... | 2011 | 22006371 |
| thyroid autoimmunity in children with coeliac disease: a prospective survey. | thyroid autoimmunity (ta) is often associated with coeliac disease (cd). | 2011 | 21862521 |
| Quality of life and patient satisfaction after video-assisted thoracic sympathicolysis for essential hyperhidrosis: a follow-up of 138 patients. | Abstract Objectives: Essential hyperhidrosis (EH) is defined as excessive functioning of the sudomotor sweat system. Definitive treatment of choice is video-assisted thoracoscopic sympathetic interruption. Success rates are high, but compensatory hyperhidrosis (CH) remains a troublesome side effect. The aim of this study was to document patient satisfaction and side effects at least 6 months after thoracoscopic sympathicolysis. Methods: Between 2001 and 2005, 246 patients underwent bilateral ... | 2011 | 22011277 |
| Plasmatic vasopressin in patients undergoing conventional infra-renal abdominal aorta aneurysm repair. | To evaluate plasmatic arginine vasopressin (AVP) levels in patients undergoing scheduled conventional abdominal aortic aneurysm (AAA) repair. | 2011 | 22086577 |
| Restriction enzyme-free construction of random gene mutagenesis libraries in Escherichia coli. | Directed evolution relies on both random and site-directed mutagenesis of individual genes and regulatory elements to create variants with altered activity profiles for engineering applications. Central to these experiments is the construction of large libraries of related variants. However, a number of technical hurdles continue to limit routine construction of random mutagenesis libraries in Escherichia coli, in particular, inefficiencies during digestion and ligation steps. Here, we report a ... | 2011 | 22155067 |
| adenine recognition is a key checkpoint in the energy release mechanism of phage t4 dna packaging motor. | atp is the source of energy for numerous biochemical reactions in all organisms. tailed bacteriophages use atp to drive powerful packaging machines that translocate viral dna into a procapsid and compact it to near-crystalline density. here we report that a complex network of interactions dictates adenine recognition and atp hydrolysis in the pentameric phage t4 large "terminase" (gp17) motor. the network includes residues that form hydrogen bonds at the edges of the adenine ring (q138 and q143) ... | 2011 | 22100308 |
| significant association between thyroid hormones and erythrocyte indices in euthyroid subjects. | objective hypothyroidism and hyperthyroidism are each associated with anaemia, but relationships between thyroid function and erythrocyte indices in euthyroid subjects have not been examined. the aim of this study was to examine these relationships in a community-based cohort. design, subjects and measurements linear regression models with free t4, free t3 and tsh as predictors of erythrocyte indices and serum iron parameters were fitted to data from a cohort of 1179 participants in the 1994 b ... | 2011 | 21913954 |
| Are thyroid hormone concentrations at birth associated with subsequent autism diagnosis? | Thyroid hormones substantially influence central nervous system development during gestation. We hypothesized that perturbations of early thyroid profiles may contribute to the development of autism spectrum disorders (ASD). Thyroid pathways could provide a mechanism by which environmental factors that affect the thyroid system may impact autism occurrence or phenotypic expression. We investigated whether thyroxine (T4) levels at birth are associated with subsequent ASD, using two existing Calif ... | 2011 | 21882364 |
| [Thyreopathy in primary care]. | Thyroid gland disorders, as the core of all endocrinopathies, affect 5-7% of the population of the Czech Republic, with women being affected 6-8 times more often than men. Clinically, thyreopathies are divided into hormonal production disorders and morphology disorders. Thyroid hormones fT3, fT4 and TSH serum levels determine the diagnosis of a thyroid gland disorder. Primary hypothyreosis is characterized by reduced fT4 and increased TSH. Low T3 syndrome is a protective reaction of the organism ... | 2011 | 21957775 |
| [Patient-controlled epidural analgesia combined with patient-controlled intravenous analgesia for postoperative analgesia after miles' operation for rectal cancer]. | A 69-year-old woman (156 cm, 53 kg) underwent a Miles' operation, total hysterectomy, resection of vagina, and thigh flap to vulva for rectal cancer. Before general anesthesia, an epidural catheter was inserted at T11-12 interspace, and 1.5% mepivacaine 7ml was administered. Sensory block level spread from T4 to L1. Anesthesia was induced with propofol and maintained with sevoflurane in air oxygen mixture. Operation was performed uneventfully. After the operation, postoperative analgesia was ach ... | 2011 | 21861422 |
| [Rectal cancer: The radiation basis of radiotherapy, target volume]. | Since the implementation of preoperative chemoradiotherapy and mesorectal excision, the 5-year rates of locoregional failures in T3-T4 N0-N1 M0 rectal cancer fell from 25-30% thirty years ago to 5-8% nowadays. A critical analysis of the locoregional failures sites and mechanisms, as well as the identification of nodal extension, helps the radiation oncologist to optimize the radiotherapy target definition. The upper limit of the clinical target volume is usually set at the top of the third sacra ... | 2011 | 21890393 |
| modulation of the processive abasic site lyase activity of a pyrimidine dimer glycosylase. | the repair of cis-syn cyclobutane pyrimidine dimers (cpds) can be initiated via the base excision repair (ber) pathway, utilizing pyrimidine dimer-specific dna glycosylase/lyase enzymes (pdgs). however, prior to incision at lesion sites, these enzymes bind to non-damaged dnas through charge-charge interactions. following initial binding to dna containing multiple lesions, the enzyme incises at most of these sites prior to dissociation. if a subset of these lesions are in close proximity, cluster ... | 2011 | 21889915 |
| two pathways for rnase e action in escherichia coli in vivo and bypass of its essentiality in mutants defective for rho-dependent transcription termination. | the endonuclease rnase e of escherichia coli is essential for viability, but deletion of its c-terminal half (cth) is not lethal. rnase e preferentially acts on 5'-monophosphorylated rna whose generation from primary transcripts is catalysed by rpph, but δrpph strains are viable. here we show that the rnase e-δcth δrpph combination is lethal, and that the lethality is suppressed by rho or nusg mutations impairing rho-dependent transcription termination. lethality was correlated with defects in b ... | 2011 | 22026368 |
| quality of life in breast cancer survivors: 2 years post self-management intervention. | introduction: today, cancer survivors have an added new role to self manage living with the medical, emotional and role tasks that can affect their quality of life (qol). the purpose of the study was to evaluate the qol of women two years after participating in a self-management intervention program. method: the clinical trial was conducted at university malaya medical centre between 2006 and 2008. the experimental group underwent a 4-week self management program, and the control group underwent ... | 2011 | 22126488 |
| medical image analysis: computer-aided diagnosis of gastric cancer invasion on endoscopic images. | background: the aim of this study was to investigate the efficacy of diagnosing depth of wall invasion of gastric cancer on endoscopic images using computer-aided pattern recognition. methods: the back propagation algorithm was used for computer training. data of 344 patients who underwent gastrectomy or endoscopic tumor resection between 2001 and 2010 and their 902 endoscopic images were collected. the images we ... | 2011 | 22083334 |
| regulation of adiponectin gene expression in adipose tissue by thyroid hormones. | available experimental data suggest that adiponectin and thyroid hormones have biological interaction in vivo. however, the effects of thyroid hormones on adipose adiponectin gene expression in thyroid dysfunction are unclear. we induced hyper- (hyper) and hypothyroidism (hypo) by daily administration of a 12 mg/l of levothyroxine and 250 mg/l of methimazole in drinking water of rats, respectively, for 42 days. the white adipose tissues and serum sample were taken on days 15, 28, 42 and also 2 w ... | 2011 | 22127636 |
| [pharmacological effects of oleum cinnamomi and water extract of cortex cinnamomi in rats with yang-deficiency cold syndrome and the mathematical analysis]. | to compare the effects of oleum cinnamomi and water extract of cortex cinnamomi in rats with yang-deficiency cold syndrome based on mathematical analysis. | 2011 | 21906523 |
| positive correlation between type 1 and 2 iodothyronine deiodinases activities in human goiters. | type 1 (d1) and 2 (d2) iodothyronine deiodinases are selenocysteine-containing enzymes that catalyze the deiodination of t4 to t3 in the thyroid and in peripheral tissues. despite their importance to the plasma t3 pool in human beings, there are few studies about their behavior in human thyroids. in order to better understand iodothyronine deiodinase regulation in the thyroid gland, we studied thyroid tissue samples from follicular adenoma (ad, n = 5), toxic diffuse goiter (tdg, n = 6), nontoxic ... | 2011 | 22207295 |
| differentiated thyroid carcinomas in childhood: clinicopathologic results of 26 patients. | epithelial solid tumors which are rare in childhood are responsible for about 9% of all childhood cancers. however, differentiated thyroid carcinomas (dtcs) are the most common of the endocrine neoplasia (0.5%-3%) in all childhood malignancies. pediatric thyroid cancers have some clinicopathological differences from adult thyroid cancers. this analysis investigates the clinical behavior and pathological characteristics of childhood thyroid cancers, with treatment options and outcomes. a total of ... | 2011 | 22145466 |
| subclinical hypothyroidism and cardiovascular risk: recommendations for treatment. | the definition of subclinical hypothyroidism (sch) is solely biochemical: a serum free t4 level within the reference range in the presence of an elevated serum thyroid-stimulating hormone (tsh) level. while overt hypothyroidism is associated with an increased cardiovascular disease risk, sch, the mildest form of hypothyroidism, may also be associated with an increased cardiovascular disease risk, but to a lesser degree. recent evidence points to a significant trend toward an increase in cardiova ... | 2011 | 21983317 |
| membrane and nuclear permeabilization by polymeric pdna vehicles: efficient method for gene delivery or mechanism of cytotoxicity? | the aim of this study is to compare the cytotoxicity mechanisms of linear pei to two analogous polymers synthesized by our group: a hydroxyl-containing poly(l-tartaramidoamine) (t4) and a version containing an alkyl chain spacer poly(adipamidopentaethylenetetramine) (a4) by studying the cellular responses to polymer transfection. we have also synthesized analogues of t4 with different molecular weights (degrees of polymerization of 6, 12, and 43) to examine the role of molecular weight on the c ... | 2011 | 22175236 |
| effects of adjuvant treatment on cognitive function in women with early breast cancer. | purpose: whether adjuvant therapy impairs cognitive function in women with breast cancer (bc) is unclear. we determined the effects of adjuvant therapy on cognitive function in women with early bc. methods: we consecutively and prospectively enrolled women aged 40-69 years who had a positive radiographic finding from the mammography screening program at stockholm south general hospital. all women completed the headminder web-based neuropsychological battery cognitive stability index (csi) for re ... | 2011 | 21908235 |
| analysis of the seventh edition of american joint committee on colon cancer staging. | purpose: the seventh edition of the american joint committee on cancer (ajcc) staging system has new substages for colon cancer. we used survival data from a single medical center to analyze this new ajcc edition. methods: the colon cancer database of taipei veterans general hospital provided 1,865 patient records covering from 1999 to 2005. survival rates were evaluated using the kaplan-meier method. ... | 2011 | 22146786 |
| factors influencing the outcomes of primary surgery with postoperative radiotherapy for pn2 oropharyneal squamous cell carcinoma. | the purpose of this study was to examine treatment outcomes and define factors that influence survival in patients with pn2 oropharyngeal carcinoma. fifty-five patients underwent primary surgery with postoperative radiotherapy between 1994 and 2009. primary tumor sites were 36 tonsil, 13 base of tongue, 3 soft palate, and three posterior pharyngeal wall. there were 15, 26, 5, and 9 patients with stage t1 to t4 cancers, respectively. the n stage were 5 n2a, 37 n2b, and 13 n2c. the 5-year disease- ... | 2011 | 21924946 |
| estimation of stature from the foot and its segments in a sub-adult female population of north india. | abstract: | 2011 | 22104433 |
| serum tsh level in healthy koreans and the association of tsh with serum lipid concentration and metabolic syndrome. | the proper treatment of subclinical hypothyroidism and the normal range of serum thyroid stimulating hormone (tsh) concentration are intensely debated. however, few reports have investigated tsh concentrations in asian ethnic groups. therefore, the present study was designed to define the tsh reference range in a korean population and to investigate the metabolic significance of tsh concentration. | 2011 | 22205844 |
| diagnostic and prognostic significance of prostate specific antigen and serum interleukin 18 and 10 in patients with locally advanced prostate cancer: a prospective study. | background: prostate cancer is one of the most common cancers afflicting men today. prostate biopsy, an invasive procedure is generally used for diagnoses but attempts are being made to find accurate and precise non- invasive biomarkers. diagnostic accuracy of prostate specific antigen (psa) has been well documented. serum interleukin-18 (il-18) and interleukin-10 (il-10) have shown their diagnostic ability in other cancers but not investigated well in prostate cancer. this study, thus determine ... | 2011 | 22126577 |
| adaptive radiotherapy for head-and-neck cancer: initial clinical outcomes from a prospective trial. | purpose: to present pilot toxicity and survival outcomes for a prospective trial investigating adaptive radiotherapy (art) for oropharyngeal squamous cell carcinoma. methods and materials: a total of 24 patients were enrolled in an institutional review board-approved clinical trial; data for 22 of these patients were analyzed. daily ct-guided setup and deformable image registration permitted serial mapping of clinical target volumes and avoidance structures for art planning. primary site was bas ... | 2011 | 22138459 |
| effects of butachlor on reproduction and hormone levels in adult zebrafish (danio rerio). | butachlor, a chloracetamide herbicide, is widely used in china. in the present study, paired adult male and female zebrafish (danio rerio) were exposed to various concentrations of butachlor (0, 25, 50 and 100μg/l) for 30 days, and the effects on reproduction and endocrine disruption were evaluated using fecundity, condition factor (cf), gonadosomatic index (gsi), liver somatic index (lsi), plasma vitellogenin (vtg), sex steroids and thyroid hormone levels as endpoints. our results showed that t ... | 2011 | 21920721 |
| clinical pathology of greyhounds and other sighthounds. | owing to the development of greyhounds as racing sighthounds, these dogs have acquired unique physiologic adaptations that distinguish them from other breeds. reference intervals for many analytes in retired racing greyhounds (rrgs) differ from those of other breeds; most of the hematologic differences have also been described in other sighthounds. in this review, we provide a survey of the literature on clinical pathology of greyhounds and other sighthounds and results of laboratory testing, in ... | 2011 | 22092909 |
| the c-terminal domain of the adenomatous polyposis coli (apc) protein is involved in thyroid morphogenesis and function. | adenomatous polyposis coli (apc) is a multifunctional protein as well as a tumor suppressor. to determine the functions of the c-terminal domain of apc, we have investigated apc ( 1638t/1638t ) mice, which express a truncated apc that lacks the c-terminal domain. apc ( 1638t/1638t ) mice are tumor free and exhibit growth retardation. in the present ... | 2011 | 22179183 |
| evaluation of adjuvant chemoradiation therapy for ampullary adenocarcinoma: the johns hopkins hospital-mayo clinic collaborative study. | the role of adjuvant chemoradiation therapy for ampullary carcinoma is unknown. previous literature suggests that certain populations with high risk factors for recurrence may benefit from adjuvant chemoradiation. we combined the experience of two institutions to better delineate which patients may benefit from adjuvant chemoradiation. | 2011 | 21951377 |
| Complete Genome Sequence of the Giant Virus OBP and Comparitive Genome Analysis of the Diverse {varphi}KZ-Related Phages. | The 283,757 bp dsDNA genome of Pseudomonas fluorescens phage OBP shares a general genomic organization with Pseudomonas aeruginosa phage EL. Comparison of this genomic organization assembled in syntenic genomic blocks interspersed with hyperplastic regions of the ?KZ-related phages, supports the proposed division in the "EL-like viruses", and the "phiKZ-like viruses" within a larger subfamily. Identification of putative early transcription promoters scattered throughout the hyperplastic regions, ... | 2011 | 22130535 |
| Diet exposure to technical hexabromocyclododecane (HBCD) affects testes and circulating testosterone and thyroxine levels in American kestrels (Falco sparverius). | Hexabromocyclododecane (HBCD) is a high-production-volume, brominated flame-retardant that is used in items such as polystyrene foams. HBCD has been detected in the environment, wildlife tissues and in humans globally with some of the highest recorded levels in predatory birds. This study examined the effects of exposure to environmentally relevant levels of HBCD on the reproductive physiology of captive male American kestrels (Falco sparverius), a predatory bird. Two sets of males were used: on ... | 2011 | 21917248 |
| Swallowing function after transoral laser microsurgery (TLM) ± adjuvant therapy for advanced-stage oropharyngeal cancer. | To perform a longitudinal description of swallowing function following transoral laser microsurgery (TLM) ± adjuvant therapy for advanced-stage oropharyngeal cancer (OPC) and identify prognostic factors associated with swallowing performance. | 2011 | 21882203 |
| Multi-Institutional Analysis of Robotic Radical Cystectomy for Bladder Cancer: Perioperative Outcomes and Complications in 227 Patients. | Abstract Purpose: Recently, some surgeons have begun to describe single-institution case series with less invasive surgical approaches to bladder cancer such as laparoscopic or robotic-assisted techniques. We report on a multi-institutional, multi-surgeon experience with robotic radical cystectomy with regard to operative and pathologic outcomes and complications to evaluate the feasibility and reproducibility of this technique in a large cohort of patients. Subjects and Methods: Two hundred ... | 2011 | 22142028 |
| Structure-function analysis of HsiF, a gp25-like component of the type VI secretion system, in Pseudomonas aeruginosa. | Bacterial pathogens use a range of protein secretion systems to colonize their host. One recent addition to this arsenal is the type VI secretion system (T6SS), which is found in many Gram-negative bacteria. The T6SS involves 12-15 components, including a ClpV-like AAA(+) ATPase. Moreover, the VgrG and Hcp components have been proposed to form a puncturing device, based on structural similarity to the tail spike components gp5/gp27 and the tail tube component gp19 of the T4 bacteriophage, respec ... | 2011 | 21873404 |
| Gastrectomy as a secondary surgery for stage IV gastric cancer patients who underwent S-1-based chemotherapy: a multi-institute retrospective study. | BACKGROUND: Current advances in chemotherapy provide opportunities for stage IV gastric cancer patients with distant metastasis to undergo potentially curable resection. There are, however, few data on gastrectomy as a secondary surgery aimed at rendering such patients cancer-free. METHODS: We investigated stage IV gastric cancer patients who underwent surgery with curative intent after S-1-based chemotherapy bet ... | 2011 | 22033890 |
| multiple synchronous primary tumours in a single lobe. | we present the case of a 70-year-old man with three synchronous histologically different primary tumours in the same lobe. he initially presented with an intermittent productive cough, dyspnoea and non-specific abdominal pains. radiological investigation revealed three areas of high-intensity fludeoxyglucose uptake of varying size within the right upper lobe. he underwent thoracoscopic right upper lobectomy. histological analysis confirmed the three lesions to be undifferentiated squamous cell c ... | 2011 | 22159234 |
| Sequential evaluations of trace elements in patients receiving parenteral nutrition. | To evaluate alterations of serum trace element (TE) levels in critically ill patients receiving parenteral nutrition (PN) including the recommended doses of TEs. | 2011 | 21940305 |
| The evaluation of SOX9 expression and its relationship with carcinoembryonic antigen-related cell adhesion molecule 1 in gastric neoplastic and nonneoplastic lesions. | The aims of this study were to investigate the expression of SOX9 (sex determining region Y [SRY]-related high-mobility group box 9) and carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in benign, premalignant, and malignant gastric lesions and to explore the association between SOX9 and CEACAM1 in gastric carcinogenesis. SOX9 and CEACAM1 expression was detected in normal gastric mucosa, hyperplastic polyp, intestinal metaplasia, gastric intraepithelial neoplasia, and adenocar ... | 2011 | 22209504 |
| Solution structure of a minor and transiently formed state of a T4 lysozyme mutant. | Proteins are inherently plastic molecules, whose function often critically depends on excursions between different molecular conformations (conformers). However, a rigorous understanding of the relation between a protein's structure, dynamics and function remains elusive. This is because many of the conformers on its energy landscape are only transiently formed and marginally populated (less than a few per cent of the total number of molecules), so that they cannot be individually characterized ... | 2011 | 21857680 |
| oral maxillary squamous carcinoma: an indication for neck dissection in the clinically negative neck. | this multicenter study was undertaken to characterize the metastatic behavior of oral maxillary squamous carcinoma and to determine the role of selective neck dissection. | 2011 | 21990223 |
| impact of subclinical hypothyroidism treatment in systolic and diastolic cardiac function. | to evaluate the effects of levothyroxine (l-t4) replacement in echocardiographic parameters of middle-aged women with subclinical hypothyroidism (sh). | 2011 | 22147094 |
| Plasma progesterone, metabolic hormones and beta-hydroxybutyrate in Holstein-Friesian cows after superovulation. | Metabolic hormones [insulin, leptin, insulin-like growth factor-I (IGF-I), thyroxine (T4) and triiodothyronine (T3)], progesterone (P4) and beta-hydroxybutyrate (BHB) serum concentrations were evaluated and their effect on the superovulation results of donor cows was investigated in a semi-arid environment. Body weight, body condition score (BCS) and lactation stage were also included in the analysis. Twenty-three Holstein-Friesian cows were superovulated with 600 IU FSHp following the routine p ... | 2011 | 22079709 |
| thoracic paravertebral block for video-assisted thoracoscopic surgery: single injection versus multiple injections. | thoracic paravertebral blocks (pvbs) have been shown to be effective for analgesia after video-assisted thoracoscopic surgery (vats) with single- and multiple-injection techniques. the efficacy of single-injection pvb was compared with multiple-injection pvb on postoperative analgesia in vats was studied. | 2011 | 22055006 |
| effects of sitting up for five minutes versus immediately lying down after spinal anesthesia for cesarean delivery on fluid and ephedrine requirement; a randomized trial. | patient position after spinal anesthesia has had variable effects on blood pressure and ephedrine requirements. the aim of this study was to determine the effects that sitting the patient up for five minutes after spinal anesthesia would have on intraoperative fluid and ephedrine requirements. | 2011 | 21971743 |
| treatment of chronic chest wall pain in a patient with loeys-dietz syndrome using spinal cord stimulation. | spinal cord stimulation (scs) has been used with increased frequency for the treatment of intractable pain including chronic chest pain. | 2011 | 21992158 |
| concomitant boost radiotherapy and multidrug chemotherapy in the neoadjuvant treatment of locally advanced rectal cancer: results of a phase ii study. | an intensified multidrug chemotherapy regimen (raltitrexed plus oxaliplatin, tom-ox) plus concomitant boost radiotherapy, in the neoadjuvant treatment of locally advanced rectal cancer patients, was shown feasible in our previous study. the aim of this study was to evaluate the efficacy in terms of pathologic complete response to pre-operative therapy. | 2011 | 21851185 |
| Prevalence of acanthamoeba from tap water in rio grande do Sul, Brazil. | A total of 136 samples of tap water were collected from state and municipal schools between March and November 2009. The samples were filtered through cellulose nitrate membranes that were seeded at non-nutrient agar 1.5% containing an overlayer of Escherichia coli suspension. Thirty-one (22.79%) tap water samples investigated were found positive for free-living amoebae (FLA). From these, 13 presented as FLA that seems to belong to the genus Acanthamoeba. All samples of FLA were cloned and ident ... | 2011 | 21882008 |
| Pilot study: individualized training for caregivers of hospitalized older veterans. | : The hospital-to-home transition represents a vulnerable time for older veterans who are more medically and socioeconomically challenged than the general population of older adults. | 2011 | 22067595 |
| Evaluation of hybrid treatments to produce high quality reuse water. | Four tertiary hybrid treatments to produce high quality reused water, fulfilling Brazilian drinking water regulations, from a slaughterhouse's secondary treated effluent were evaluated. The pilot plant with a capacity of 500 L h(-1) was set up and consisted of these stages: pre-filtration system (cartridge filter 50 micron, activated carbon filter, cartridge filter 10 micron), oxidation (H2O2) or second filtration (ceramic filter, UF) followed by UV radiation (90 L h(-1)). The best combination w ... | 2011 | 21902048 |