Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| childhood sexual abuse and hypothalamus-pituitary-thyroid axis in postpartum major depression. | the aim of this study was to investigate the association between early life events in women with postpartum major depression and concomitant hypothalamus-pituitary-thyroid axis disturbances (hptd), thyroid dysfunction or presence of thyroid antibodies. | 2010 | 19740549 |
| the impact on survival of positive intraoperative pleural lavage cytology in patients with non-small-cell lung cancer. | the aim of this study was to analyze intraoperative pleural lavage cytology results in patients with non-small-cell lung cancer and quantify the impact on survival and recurrence. | 2010 | 19765741 |
| chromogranin a (cga) serum level as a marker of progression in hepatocellular carcinoma (hcc) of elderly patients. | the observation of neuroendocrine (ne) activity during clinical course of hepatocellular carcinoma (hcc), suggested the use of ne serum markers to detect it. thus we have evaluated the usefulness of serum measurements of cga in monitoring disease activity of hcc. we investigated the role of serum concentrations of cga, alpha-fetoprotein (afp) and des-gamma-carboxyl-prothrombin (dcp) in 55 patients with hcc, 27 patients with cirrhosis, 22 patients with chronic hepatitis and a control group of 20 ... | 2010 | 19766330 |
| assisting the diagnosis of graves' hyperthyroidism with bayesian-type and som-type neural networks by making use of a set of three routine tests and their correlation with free t4. | in our previous paper, we proposed a novel screening method that assists the diagnosis of graves' hyperthyroidism via two types of neural networks by making use of routine test data. this method can be applied by non-specialists during physical check-ups at a low cost and is expected to lead to rapid referrals for examination and treatment by thyroid specialists, that is, to improve patients' qol. in this report, the amount of female sample data was increased and routine test data (14 parameters ... | 2010 | 19762198 |
| tertiary butyl alcohol in drinking water induces phase i and ii liver enzymes with consequent effects on thyroid hormone homeostasis in the b6c3f1 female mouse. | tertiary butyl alcohol (tba) was administered to groups of 15 female b6c3f1 mice in drinking water at concentrations of 0, 2.0 or 20 mg tba ml(-1), for 14 days, for assessment of gross and histological changes in the liver and thyroid, thyroid hormones (t3, t4, and tsh), total hepatic cytochrome p450 (cyp) content, specific cyp activities and quantitative pcr analysis of specific cyp enzymes (cyp1a1, cyp2b9, cyp2b10, cyp3a11), sulfuryltransferases (st1a1, st2a2, and stn) and glucuronyltransferas ... | 2010 | 19760798 |
| annual sex steroid and other physiological profiles of pacific lampreys (entosphenus tridentatus). | we documented changes in plasma levels of estradiol 17-beta (e2), progesterone (p), 15alpha-hydroxytestosterone (15alpha-t), thyroxine (t4), triiodothyronine (t3), protein, triglycerides (tgs), and glucose in adult pacific lampreys (entosphenus tridentatus) held in the laboratory in two different years. levels of e2 in both sexes ranged from 0.5 to 2 ng/ml from september to march, peaked in late april (2-4 ng/ml), and decreased in may, with levels higher in males than in females. levels of p wer ... | 2010 | 19782759 |
| the role of thyroid hormone in the pathophysiology of heart failure: clinical evidence. | thyroid hormone (th) has a fundamental role in cardiovascular homeostasis in both physiological and pathological conditions, influencing cardiac contractility, heart rate (hr), diastolic function and systemic vascular resistance (svr) through genomic and non-genomic mediated effects. in heart failure (hf) the main alteration of thyroid function is referred to as "low-triiodothyronine (t3) syndrome" (lt3s) characterized by decreased total serum t3 and free t3 (ft3) with normal levels of thyroxine ... | 2010 | 19110971 |
| cardiac hypertrophy and thyroid hormone signaling. | thyroid hormone exerts a large number of influences on the cardiovascular system. increased thyroid hormone action increases the force and speed of systolic contraction and the speed of diastolic relaxation and these are largely beneficial effects. furthermore, thyroid hormone has marked electrophysiological effects increasing heart rate and the propensity for atrial fibrillation and these effects are largely mal-adaptive. in addition, thyroid hormone markedly increases cardiac angiogenesis and ... | 2010 | 19125327 |
| the combination of docetaxel and cisplatin plus fluorouracil as neoadjuvant chemotherapy in the treatment of t4 stage gastric cancer. | the prognosis of local advanced gastric carcinoma is very poor. we evaluated the impact on survival and the effects induced by the triple combination docetaxel-cisplatin-fluorouracil (dcf) as neoadjuvant chemotherapy in 24 t4 stage gastric tumor patients. they received 2-3 cycles dcf chemotherapy, followed by radical gastric resection. tumor downstaging detected by ct was obtained in 17 out of 24 patients. the overall 3-year survival rate was 68.2%. patients who received r0 resection (19/22) sho ... | 2010 | 19006661 |
| cytotoxic effects exerted by polyarylsulfone dialyser membranes depend on different sterilization processes. | polyarylsulfone group is one of the most important polymeric materials used in the biomedical field, due to its excellent properties, such as good thermal, chemical, and mechanical stability. there are three important polyarylsulfone polymers, all of which have excellent electrical properties: polysulfone (psu), polyarylsulfone (pas) and polyarylethersulfone (paes). all these polymers have excellent creep, radiation and high temperature resistance. in this study, we aimed to determine the effect ... | 2011 | 19795219 |
| despite the lack of association between different genotypes and the presence of prostate cancer, endothelial nitric oxide synthase a/b (enos4a/b) polymorphism may be associated with advanced clinical stage and bone metastasis. | to investigate the relationship between the distribution of endothelial no synthase (enos4a/b) gene polymorphism and clinical features of prostate cancer (pca). | 2011 | 19576798 |
| analysis of mel-18 expression in prostate cancer tissues and correlation with clinicopathologic features. | mel-18 is a member of the polycomb group (pcg) of proteins, which are chromatin regulatory factors that play an important role in development and oncogenesis. this study was designed to investigate the clinical and prognostic significance of mel-18 in the patients with prostate cancer. | 2011 | 19395284 |
| baseline renal function status limits patient eligibility to receive perioperative chemotherapy for invasive bladder cancer and is minimally affected by radical cystectomy. | to evaluate the proportion of patients with muscle-invasive urothelial carcinoma (uc) who would be eligible to receive cisplatin-based chemotherapy before and after radical cystectomy based on renal function. | 2011 | 20709369 |
| predictors and survival of synchronous peritoneal carcinomatosis of colorectal origin: a population-based study. | the aim of our study was to provide population-based data on incidence and prognosis of synchronous peritoneal carcinomatosis and to evaluate predictors for its development. diagnosed in 1995-2008, 18,738 cases of primary colorectal cancer were included. predictors of peritoneal carcinomatosis were analysed by multivariable logistic regression analysis. median survival in months was calculated by site of metastasis. in the study period, 904 patients were diagnosed with synchronous peritoneal car ... | 2011 | 20715167 |
| novel zeb1 expression in bladder tumorigenesis. | what's known on the subject? and what does the study add? epithelial-mesenchymal transition (emt) is involved in tumor progression where the underlying cellular changes associated with emt have been identified in in vitro models and confirmed in a limited number of in vivo studies. zeb1, which targets e-cadherin repression, is a transcriptional regulator that has been implicated in emt, and is associated with uterine and colorectal cancers. regulation of zeb1 expression has been shown to involve ... | 2011 | 20735391 |
| serum thyroxine and age - rather than thyroid volume and serum tsh - are determinants of the thyroid radioiodine uptake in patients with nodular goiter. | radioiodine (131i) therapy is widely used for treatment of non-toxic goiters. a limitation for this treatment is a low thyroid radioiodine uptake (raiu), often encountered in these patients. | 2011 | 20834199 |
| a modified plasmid vector pcmv-3tag-lic for rapid, reliable, ligation-independent cloning of polymerase chain reaction products. | here we present a modified vector pcmv-3taq-lic for a rapid, simple, and relatively cheap method to build expression constructs. after being digested by nt.bspqi and ecorv, a lineal vector with specific 11-base single overhangs is obtained. polymerase chain reaction (pcr) products with complementary overhangs are created by building appropriate extensions into the primers and treating them with t4 dna polymerase. the annealing of the insert and the vector is performed in the absence of ligase by ... | 2011 | 20816743 |
| adhesion pattern and prognosis studies of t4n0m0 colorectal cancer following en bloc multivisceral resection: evaluation of t4 subclassification. | in current tnm stage system, t4 lesions represent a complex group and should be considered to further optimize the classification. this study evaluates the significance of adhesion pattern in t4 subclassification based on prognostic analysis of t4n0m0 colorectal cancer following en bloc multivisceral resection (mvr). prospectively collected data (1992-2004) were analyzed for 278 patients with stage t4n0m0 lesions following mvr for colorectal cancer. patients were divided into inflammatory adhesi ... | 2011 | 20740326 |
| effect of hypothyroidism on postnatal conjunctival development in rats. | to study the conjunctival development in hypothyroid genetically epilepsy-prone rats (geprs) with serum t3 and t4 significantly lower than in normal rats. | 2011 | 20798563 |
| effects of breast cancer surgery and surgical side effects on body image over time. | we examined the impact of surgical treatments (breast-conserving surgery [bcs], mastectomy alone, mastectomy with reconstruction) and surgical side-effects severity on early stage (0-iia) breast cancer patients' body image over time. we interviewed patients at 4-6 weeks (t1), six (t2), 12 (t3), and 24 months (t4) following definitive surgical treatment. we examined longitudinal relationships among body image problems, surgery type, and surgical side-effects severity using the generalized estimat ... | 2011 | 20686836 |
| overall and cause-specific survival for patients undergoing lobectomy, near-total, or total thyroidectomy for differentiated thyroid cancer. | the extent of surgery for well-differentiated thyroid cancer remains controversial. the purpose of this study was to evaluate the type of resection, age, t classification, nodal status, tumor size, and year of diagnosis for overall survival (os) and cause-specific survival (css) using a large database. | 2011 | 20687168 |
| influence of topical dexamethasone applications on insulin, glucose, thyroid hormone and cortisol levels in dogs. | the influence of two topical dexamethasone applications (dermal and ototopical) on plasma insulin, glucose, thyroid hormone and cortisol levels was investigated in beagle dogs. both treatments significantly decreased basal cortisol values, associated with exaggerated rise in insulin (∼50%), together with unchanged serum glucose levels. dermal dexamethasone quickly decreased plasma thyroxin (t(4)) levels; whereas dexamethasone in ear drops gradually inhibited time-dependently t(4) release (18-50% ... | 2011 | 20667567 |
| laser-evoked potentials habituation in fibromyalgia. | abnormalities of central pain processing play an important role in the pathophysiology of fibromyalgia (fm). the aims of the present study were to: 1) evaluate habituation of laser-evoked potentials (lep) to repeated painful stimulation of 1 tender and 2 nontender points; and 2) determine correlations between lep abnormalities and major clinical features of fm. fourteen consecutive fm outpatients and 13 normal controls were included. lep were recorded from scalp designations fz, cz, pz, t3, and ... | 2011 | 20685171 |
| early avoidance of disease- and treatment-related distress predicts post-traumatic stress in parents of children with cancer. | purpose of the research: it has previously been demonstrated that parents of children with cancer often exhibit symptoms of post-traumatic stress (ptss) even though the child's treatment is successfully completed. for the development of interventions we need to identify predictors of ptss, which are possible to influence. based on contemporary learning theory, it was hypothesized that early avoidance of disease- and treatment-related distress would predict the development of parental post-trauma ... | 2011 | 20591735 |
| t4 colorectal cancer: is laparoscopic resection contraindicated? | t4 colorectal cancer remains a contraindication for laparoscopy. it is argued that the risk of incomplete resection could be higher than in open surgery. furthermore, difficulty in dissection could lead to a very high rate of conversion. there is little information on this. the study aimed at assessing feasibility and operative and oncologic results of laparoscopic resection for t4 colorectal cancer. | 2011 | 20653697 |
| effects of unfractioned heparin and low-molecular-weight heparin on osteoprotegerin and rankl plasma levels in haemodialysis patients. | this randomized crossover study investigated the effects of unfractioned heparin (ufh) and low-molecular-weight heparin (lmwh) on intra- and post-dialytic blood levels of osteoprotegerin (opg), receptor activator of nuclear factor kappa b ligand (rankl) and inflammatory cytokines. | 2011 | 20659908 |
| feed utilisation of ethiopian highland lambs on a basal diet of eleucine coracana straw and supplemented with variously sourced protein mixed with wheat bran. | the study investigated the effect of supplementation of a basal diet of eleucine coracana (finger millet) straw with different protein sources mixed with wheat bran on feed utilisation in ethiopian highland lambs. twenty yearling intact male lambs (14.9 ± 0.30 kg; mean ± sd) were used in a randomised complete block design. dietary treatments included a basal diet of e. coracana straw ad libitum (t1); basal diet supplemented with a mixture of 222 g noug seed (guizotia abyssinica) cake (nsc) and 7 ... | 2011 | 20661642 |
| stress-induced pseudocyst formation--a newly identified mechanism of protection against organic solvents in acanthamoebae of the t4 genotype. | differentiation into highly resistant double-walled cysts is a major mechanism allowing amphizoic acanthamoebae to survive under long-lasting, unfavourable environmental conditions. we found that relatively low concentrations of methanol, acetone or dmso stimulate promptacanthamoebadifferentiation into a rounded cyst-like stage with a single envelope. to address whether this rapid response differs from the encystment, time-dependent changes in cell surface characteristics and cyst-specific gene ... | 2011 | 20650683 |
| possible roles of phospholipase a(2) in the biological activities of acanthamoeba castellanii (t4 genotype). | using phospholipases a(2)-specific spectrophotometric assays, it was shown thata. castellaniilysates and their conditioned medium exhibit phospholipase activities. the extracellular levels of pla(2)detected were significantly reduced compared with the cell-associated enzyme (p<0.05). sphinganine, a pla(2)inhibitor showed robust amoebistatic properties but had no effect on the viability ofa. castellanii. the potency of sphinganine was demonstrated effectively towards purified pla(2)derived from p ... | 2011 | 20650684 |
| effects of housing and short-term transportation on hormone and lymphocyte receptor concentrations in beef cattle. | the experiment was designed to evaluate the effects of housing system and short-term transportation on the pituitary and adrenal response and on blood progesterone concentrations of beef cattle. since the use of steroid hormones in farm animals has been banned in the eu (council directive 96/22/ec), it seems important to study the possible modifications in serum progesterone concentrations induced by stress in cattle. thirty-two, 6 months old male piedmontese beef cattle (16 reared in a littered ... | 2011 | 20646728 |
| synthetic symmetrization in the crystallization and structure determination of cela from thermotoga maritima. | protein crystallization continues to be a major bottleneck in x-ray crystallography. previous studies suggest that symmetric proteins, such as homodimers, might crystallize more readily than monomeric proteins or asymmetric complexes. proteins that are naturally monomeric can be made homodimeric artificially. our approach is to create homodimeric proteins by introducing single cysteines into the protein of interest, which are then oxidized to form a disulfide bond between the two monomers. by in ... | 2011 | 21082721 |
| prevention of complications following pelvic exenteration with the use of mammary implants in the pelvic cavity: technique and results of 28 cases. | with the evolution of neo-adjuvant therapy and the introduction of peritonectomy with chemotherapy in surgical practice, pelvic exenteration has taken second place in the treatment of advanced pelvic tumors. this surgery remains the first of choice for the treatment of t4 superior and medium rectal tumors that are not susceptible to neo-adjuvant radiochemotherapy, for uterine tumors and cervical figo iv t4, for pelvic recurrence and for t4 bladder tumors. after a pelvic exenteration the pelvic c ... | 2011 | 21031464 |
| synthesis, two-photon absorption and optical limiting properties of multi-branched styryl derivatives based on 1,3,5-triazine. | five new multi-branched two-photon absorption triazine chromophores (t1-t5) with different donor strength, conjugation length, and direction of charge transfer have been designed and synthesized. the one-photon fluorescence, fluorescence quantum yields, and two-photon properties have been investigated. the two-photon absorption (2pa) cross sections measured by the open aperture z-scan technique were determined to be 447, 854, 1023, 603, and 766 gm for t1, t2, t3, t4, and t5, respectively. this r ... | 2011 | 20973027 |
| alterations in thyroid hormone status in greenland sledge dogs exposed to whale blubber contaminated with organohalogen compounds. | as a model of high trophic level carnivores, sledge dogs were fed from 2 to 18 months of age with minke whale blubber containing organohalogen compounds (ohc) corresponding to 128 μg pcb/day. controls were fed uncontaminated porcine fat. thyroid hormone levels were assessed in 7 exposed and 7 control sister bitches (sampled at age 6-18 months) and 4 exposed and 4 control pups, fed the same diet as their mothers (sampled age 3-12 months). lower free and total t3 and t4 were seen in exposed vs. co ... | 2011 | 20888641 |
| a contemporary population-based assessment of the rate of lymph node dissection for penile carcinoma. | the adherence rate to national cancer institute (nci) recommendations regarding inguinal lymph nodes dissection (ilnd) in high grade t1 (g3t1) and t2-4 squamous cell carcinoma of the penis (sccp) is not known. we assessed ilnd rates in a north american cohort. | 2011 | 20839061 |
| cerebral cortical dynamics and the quality of motor behavior during social evaluative challenge. | to determine the influence of arousal on cerebral cortical dynamics and motor behavior, 58 channels of eeg were recorded in 13 college-age men (n=6) and women during an aiming task performed alone and in a social evaluation condition. moderate arousal, as measured by heart rate, skin conductance, and self-reported mood, was induced during the social evaluation. in accord with the yerkes-dodson hypothesis, which posits optimal performance during moderate arousal, improved performance (i.e., quali ... | 2011 | 20840197 |
| surgery and postoperative radiotherapy a valid treatment for advanced oropharyngeal carcinoma. | since 1992 we have prospectively included all head and neck cancer patients in our health region in a departmental based register. our hospital takes care of all head and neck cancer patients in our health region consisting of approximately 1 million people. in 1997, we evaluated the results of the treatment of oropharyngeal cancer in the 1992-1997 period. on the basis of this evaluation, we changed our treatment policy for tonsillar and base of tongue carcinoma. we first changed the treatment f ... | 2011 | 20803151 |
| hypothyroidism in patients with renal cell carcinoma: blessing or curse? | sunitinib and sorafenib are tyrosine kinase inhibitors that have important antitumor activity in metastatic renal cell carcinoma (mrcc). hypothyroidism constitutes a commonly reported side effect of both drugs, and particularly of sunitinib. the objective of this analysis was to investigate whether the occurrence of hypothyroidism during treatment with sunitinib and sorafenib affects the outcome of patients with mrcc. | 2011 | 20845482 |
| prospective study on the fdg-pet/ct predictive and prognostic values in patients treated with neoadjuvant chemoradiation therapy and radical surgery for locally advanced rectal cancer. | 2-[fluorine-18]fluoro-2-deoxy-d-glucose-positron emission tomography/computed tomography (fdg-pet/ct) was carried out before and after neoadjuvant chemoradiotherapy (ncrt) followed by radical surgery for locally advanced rectal cancer (larc). the aim of this study was to define its predictive and prognostic values. | 2011 | 20847032 |
| thyroid-stimulating hormone receptor and thyroid hormone receptors are involved in human endometrial physiology. | to study the expression, distribution, and function of thyroid-stimulating hormone receptor (tshr) and thyroid hormone receptors (tr) α1, α2, and β1 in human endometrium. | 2011 | 20691434 |
| impact of intracranial extension on survival in stage iv nasopharyngeal carcinoma: identification of a subset of patients with better prognosis. | t-stage is an imperfect prognostic indicator for patients with nasopharyngeal carcinoma. we evaluated the effect of extent of intracranial involvement on survival after conventional radiotherapy in patients with stage t4 nasopharyngeal carcinoma. | 2011 | 20852300 |
| determinants of eukaryal cell killing by the bacterial ribotoxin prrc. | trna damage inflicted by the escherichia coli anticodon nuclease prrc (ecoprrc) underlies an antiviral response to phage t4 infection. prrc homologs are present in many bacterial proteomes, though their biological activities are uncharted. prrcs consist of two domains: an n-terminal ntpase module related to the abc family and a distinctive c-terminal ribonuclease module. in this article, we report that the expression of ecoprrc in budding yeast is fungicidal, signifying that prrc is toxic in a e ... | 2011 | 20855293 |
| relationship between thyroid stimulating hormone and thyroid stimulating immunoglobulin in graves' hyperthyroidism. | in graves' hyperthyroidism, suppression of serum tsh after restoration of normal serum t4 and t3 with treatment has been attributed to binding of tsh-receptor antibodies to tsh receptors in the pituitary. accordingly, the relationship between tsh and serum thyroid stimulating immunoglobulin (tsi) was examined during follow-up of patients with graves' hyperthyroidism. | 2011 | 20855936 |
| impact and management of airway obstruction in patients with squamous cell carcinoma of the larynx. | we compared postoperative complications and oncologic results after laryngectomy of patients with laryngeal squamous cell carcinoma (scc), with and without airway obstruction. | 2011 | 20848422 |
| long-term results of 28 esthesioneuroblastomas managed over 35 years. | the purpose of our study was to assess the long-term results in the management of patients with esthesioneuroblastoma. | 2011 | 20848423 |
| reversion-reporter transgenes to analyze all six base-substitution pathways in arabidopsis. | to expand the repertoire of arabidopsis (arabidopsis thaliana) mutation-reporter transgenes, we constructed six mutant alleles in the same codon of the β-glucuronidase-encoding gus transgene. each allele reverts to gus+ only via a particular one of the six transition/transversion pathways. acv5 epitope tags, fused carboxyl terminal to the inactive gus- proteins, enabled semiquantitative immunoassays in plant protein extracts. spontaneous g:c→t:a transversions, previously not measured using repor ... | 2011 | 21212302 |
| direct construction of an open-sandwich enzyme immunoassay for one-step noncompetitive detection of thyroid hormone t4. | to establish a sensitive noncompetitive immunoassay for thyroxine (t4), we attempted to isolate anti-t4 antibodies from a phage display library based on a phagemid pdong1 ( dong et al. anal. biochem.2009, 36, 386 ), which was designed to enable open-sandwich enzyme-linked immunosorbent assay (os-elisa) after selection on immobilized antigen. after the fab-displaying phage library made from the splenocytes of t4-klh immunized mice was subjected to biopanning on t4-bsa, two t4-specific clones were ... | 2011 | 21214207 |
| location of si vacancies and [ti(osi)4] and [ti(osi)3oh] sites in the mfi framework: a large cluster and full ab initio study. | titanium silicalite-1 (ts-1) is an important catalyst for selective oxidation reactions. however, the nature and structure of the active sites and the mechanistic details of the catalytic reactions over ts-1 have not been well-understood, leaving a continuous debate on the genesis of active sites on the ts-1 surface in the literature. in this work, the location of si vacancies and [ti(osi)(4)] and [ti(osi)(3)oh] sites in the mfi (framework type code of zsm-5 (zeolite socony mobile-five)) framewo ... | 2011 | 21214280 |
| target localization and toxicity in dose-escalated prostate radiotherapy with image-guided approach using daily planar kilovoltage imaging. | dose escalation with intensity-modulated radiation therapy (imrt) for carcinoma of the prostate has augmented the need for accurate prostate localization prior to dose delivery. daily planar kilovoltage (kv) imaging is a low-dose image-guidance technique that is prevalent among radiation oncologists. however, clinical outcomes evaluating the benefit of daily kv imaging are lacking. the purpose of this study was to report our clinical experience, including prostate motion and gastrointestinal (gi ... | 2011 | 21214286 |
| l-thyroxine treatment in primary hypothyroidism does not increase the content of free triiodothyronine in cerebrospinal fluid: a pilot study. | the association between cerebrospinal fluid (csf) and serum concentration of thyroid hormones and pituitary thyrotropin stimulating hormone (tsh) was studied in nine hypothyroid patients (ht) before and in seven after l-thyroxine treatment. with l-thyroxine, median free t4 increased 4-fold in serum (3.5 pmol/l vs 17.5 pmol/l) and 3-fold in csf, (3.9 pmol/l vs 11.5 pmol/l). correspondingly, total t3 in serum increased two-fold (0.9 nmol/l vs 2.2 nmol/l). unexpectedly, free t3 concentration in csf ... | 2011 | 21214501 |
| the epiphyseal ring: a long forgotten anatomical structure with significant physiological function. | a descriptive study of the epiphyseal ring's structural design along the thoracolumbar spine. | 2011 | 21224766 |
| 3-t mri with phased-array surface coil in the local staging of rectal cancer. | this study sought to evaluate the diagnostic accuracy of surface-coil 3t magnetic resonance (mr) imaging in the preoperative study of patients with rectal cancer. | 2011 | 21225363 |
| the relationship between thyroid function and bone mineral density in euthyroid healthy subjects in taiwan. | it has been reported that low normal circulating thyrotropin (tsh) levels correlate with lower bone mineral density (bmd) in the korean postmenopausal female. the goal of this study is to evaluate this relationship in different sex and age groups in a chinese population. | 2011 | 21226562 |
| objective evaluation of patients with palmar hyperhidrosis submitted to two levels of sympathectomy: t3 and t4. | this study compares the results obtained of video-assisted sympathectomy performed on two distinct ganglion levels (third vs. fourth thoracic ganglion) in the treatment of palmar hyperhidrosis (ph), through a blind randomized clinical trial. all participants were randomized into two groups of 20 patients (g3 and g4) and underwent the operation, and were followed for 12 months. we used an objective method for measuring sweat, checking the transepidermal water loss (tewl), and evaluated the qualit ... | 2011 | 21233258 |
| do igf-i concentrations better reflect growth hormone (gh) action in children with short stature than the results of gh stimulating tests? evidence from the simultaneous assessment of thyroid function. | 2011 | 21232100 | |
| quantitative methods for measuring dna flexibility in vitro and in vivo. | the double-helical dna biopolymer is particularly resistant to bending and twisting deformations. this property has important implications for dna folding in vitro and for the packaging and function of dna in living cells. among the outstanding questions in the field of dna biophysics are the underlying origin of dna stiffness and the mechanisms by which dna stiffness is overcome within cells. exploring these questions requires experimental methods to quantitatively measure dna bending and twist ... | 2011 | 21195233 |
| does a subcentimeter distal resection margin adversely influence oncologic outcomes in patients with rectal cancer undergoing restorative proctectomy? | a 1-cm distal clearance margin is recommended for mid/low rectal cancers. | 2011 | 21228662 |
| [thoracic spine pseudarthrosis treated by transpleural corporectomy and bone morphogenic protein]. | traumatic thoracic spine instability is a rare but difficult-to-treat entity, particularly above t5 where pedicle screwing is widely regarded as an unsatisfactory option and anterior surgery is considered difficult because of the anatomic relationship with the shoulder and large vessels. | 2011 | 21247607 |
| hypothyroxinemia and pregnancy. | to evaluate the peer-reviewed literature on iodine deficiency and hypothyroxinemia in pregnancy. | 2011 | 21247845 |
| a brief review of voice restoration following total laryngectomy. | despite advances in conservative laryngeal surgery and radiotherapy, total laryngectomy still remains the procedure of choice for advanced-stage (uicc t3 and t4) laryngeal carcinoma, around the world. the functional rehabilitation of the laryngectomized patients has been a concern of head and neck surgeons and speech therapists. significant developments in speech rehabilitation over the past three decades have led to substantial improvements in the quality of life of these patients. the tracheoe ... | 2011 | 21248437 |
| bioenergetic impact of tissue-specific regulation of iodothyronine deiodinases during nutritional imbalance. | the regulation of energy homeostasis by thyroid hormones is unquestionable, and iodothyronine deiodinases are enzymes involved in the metabolic activation or inactivation of these hormones at the cellular level. t3 is produced through the outer ring deiodination of the prohormone t4, which is catalyzed by types 1 and 2 iodothyronine deiodinases, d1 and d2. conversely, type 3 iodothyronine deiodinase (d3) catalyzes the inner ring deiodination, leading to the inactivation of t4 into reverse triiod ... | 2011 | 21249435 |
| the effects of creep and recovery on the in vitro biomechanical characteristics of human multi-level thoracolumbar spinal segments. | several physiological and pathological conditions in daily life cause sustained static bending or torsion loads on the spine resulting in creep of spinal segments. the objective of this study was to determine the effects of creep and recovery on the range of motion, neutral zone, and neutral zone stiffness of thoracolumbar multi-level spinal segments in flexion, extension, lateral bending and axial rotation. | 2011 | 21251737 |
| lithium in drinking water and thyroid function. | background: high concentrations of lithium in drinking water were previously discovered in the argentinean andes mountains. lithium is used worldwide for treatment of bipolar disorder and treatment-resistant depression. one known side effect is altered thyroid function.objectives: we assessed associations between exposure to lithium from drinking water and other environmental sources and thyroid function.methods: women (n = 202) were recruited in four andean villages in northern argentina. lithi ... | 2011 | 21252007 |
| is a right pedicle screw always away from the aorta in scoliosis? | : study design: retrospective analysisobjective: we evaluated the aorta safety in placement of a right pedicle screw in scoliotic patients.summary of background data: past reports emphasized the aorta risk in placing pedicle screws on the concave left side in right thoracic scoliosis. however, risk on the right side has drawn limited interest.methods: thirty-four scoliotic patients with an average age of 18.0 years were evaluated. the cobb angle averaged 59.0°±14.0°. from computed tomographic da ... | 2011 | 21252823 |
| bones and crohn's: no benefit of adding sodium fluoride or ibandronate to calcium and vitamin d. | to compare the effect of calcium and cholecalciferol alone and along with additional sodium fluoride or ibandronate on bone mineral density (bmd) and fractures in patients with crohn's disease (cd). | 2011 | 21253392 |
| commentary on 't4 colorectal cancer: is laparoscopic resection contraindicated?' by bretagnol et al. | 2011 | 21255218 | |
| redox-responsive zinc finger fidelity switch in homing endonuclease and intron promiscuity in oxidative stress. | it is well understood how mobile introns home to allelic sites, but how they are stimulated to transpose to ectopic locations on an evolutionary timescale is unclear. here we show that a group i intron can move to degenerate sites under oxidizing conditions. the phage t4 td intron endonuclease, i-tevi, is responsible for this infidelity. we demonstrate that i-tevi, which promotes mobility and is subject to autorepression and translational control, is also regulated posttranslationally by a redox ... | 2011 | 21256016 |
| aortic endostent followed by extended pneumonectomy for t4 lung cancer. | pulmonary and aortic en bloc resection may be performed with cardiopulmonary bypass support, but is associated with high surgical morbidity and mortality. a 59-year-old man with left lower lobe cancer invading the aorta was considered to be unsuitable for such an extended operation because of previous myocardial infarction, coronary bypass grafts, and subsequent multiple coronary artery stenting. pneumonectomy with en bloc resection of aortic adventitia and media was accomplished after thoracic ... | 2011 | 21256322 |
| comparison of progressive cephalometric changes and postsurgical stability of skeletal class iii correction with and without presurgical orthodontic treatment. | this study compares 1) progressive dental and skeletal changes, 2) postsurgical stability, and 3) treatment efficacy of patients with skeletal class iii correction with and without presurgical orthodontic treatment. | 2011 | 21256648 |
| duplication of calsequestrin genes in teleosts: molecular characterization in the senegalese sole (solea senegalensis). | calsequestrin is a moderate-affinity, high-capacity ca(2+) binding protein in the sarcoplasmic reticulum of skeletal and cardiac muscle that seems to act as an intralumenal ca(2+) buffer. two different isoforms have been described in mammals, the skeletal and cardiac isoforms, encoded by casq1 and casq2 genes, respectively. in this study, we present molecular phylogenetic evidence of a gene duplication event of both calsequestrin genes in teleosts, referred to as casq1a/casq1b and casq2a/casq2b. ... | 2011 | 21256971 |
| mutational analysis of residues in the helical region of the class iia bacteriocin pediocin pa-1. | a 15-mer fragment that is derived from the helical region in the c-terminal half of pediocin pa-1 inhibited the activity of pediocin pa-1. of 13 other pediocin-like (hybrid) bacteriocins, only the hybrid bacteriocin sak/ped was markedly inhibited by the 15-mer fragment. sak/ped was the only one of these bacteriocins that had a sequence (in the c-terminal helix-containing half) identical to that of the 15-mer fragment, indicating that the fragment inhibits pediocin-like bacteriocins in a sequence ... | 2011 | 21257813 |
| a research framework for reducing preventable patient harm. | programs to reduce central line-associated bloodstream infections (clabsis) have improved the safety of hospitalized patients. efforts are underway to disseminate these successes broadly to reduce other types of hospital-acquired infectious and noninfectious preventable harms. unfortunately, the ability to broadly measure and prevent other types of preventable harms, especially infectious harms, needs enhancement. moreover, an overarching research framework for creating and integrating evidence ... | 2011 | 21258104 |
| hedgehog-mediated regulation of thyroid hormone action through iodothyronine deiodinases. | introduction: the three iodothyronine deiodinases catalyze the metabolic pathway that removes one iodine residue from the t4 molecule, thus producing either the active t3 or the inactive metabolite rt3. hence, deiodination is a potent mechanism by which to modulate thyroid hormone (th) action at cellular level, thereby allowing cells to customize their own t3 availability, both spatially and temporally, irrespective of th serum concentrations. sonic hedgehog (hh) regulates patterning and growth ... | 2011 | 21261564 |
| impact of neoadjuvant chemoradiotherapy followed by surgical resection on node-negative t3 and t4 non-small cell lung cancer. | this study examined the impact of neoadjuvant chemotherapy and concurrent high-dose radiation therapy on survival in patients with node-negative t3 and t4 non-small cell lung cancer. | 2011 | 21281948 |
| [knot in a thoracic epidural catheter]. | we report a case of impossible injection into a thoracic epidural catheter associated with a difficult withdrawal of this catheter after its introduction on the t3-t4 level. thanks to a gentle and continuous traction, the catheter was finally successfully removed without being broken, but presented a simple knot at 13mm from its end. no neurological complication was observed later on. this complication happened during the introduction of the catheter at the thoracic level where anatomic conditio ... | 2011 | 21282033 |
| tumor site and perigastric nodal status are the most important predictors of para-aortic nodal involvement in advanced gastric cancer. | this study was designed to identify pathological predictors of para-aortic nodal invasion in advanced gastric cancer. | 2011 | 21286941 |
| intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal. | the purpose of this study was to compare outcomes in patients with anal canal squamous cell carcinoma (scca) who were treated with definitive chemoradiotherapy by either intensity-modulated radiation therapy (imrt) or conventional radiotherapy (crt). | 2011 | 21287530 |
| the terminal region of the e. coli chromosome localises at the periphery of the nucleoid. | bacterial chromosomes are organised into a compact and dynamic structures termed nucleoids. cytological studies in model rod-shaped bacteria show that the different regions of the chromosome display distinct and specific sub-cellular positioning and choreographies during the course of the cell cycle. the localisation of chromosome loci along the length of the cell has been described. however, positioning of loci across the width of the cell has not been determined. | 2011 | 21288323 |
| a novel method for testing the veridicality of dental colour assessments. | the commission internationale de l'eclairage (cie) l*a*b* three-dimensional coordinates suggest strong correlations between the data of a* (red-green axis) and b* (blue-yellow axis), as both are located on the same plane in the model and should therefore show a strong dependency. in order to assess the veridicality of colour determinations, the null hypothesis of no significant changes in cie-a*/b* coherences of dental colours following a colour or lightness change induced by external dental ble ... | 2011 | 21289016 |
| loss of asparagine-linked glycosylation sites in variable region 5 of human immunodeficiency virus type 1 envelope is associated with resistance to cd4 antibody ibalizumab. | ibalizumab (formerly tnx-355) is a first-in-class, monoclonal antibody inhibitor of cd4-mediated human immunodeficiency type 1 (hiv-1) entry. multiple clinical trials with hiv-infected patients have demonstrated the antiviral activity, safety, and tolerability of ibalizumab treatment. a 9-week phase ib study adding ibalizumab monotherapy to failing drug regimens led to transient reductions in hiv viral loads and the evolution of hiv-1 variants with reduced susceptibility to ibalizumab. this repo ... | 2011 | 21289125 |
| the volumetric analysis of cement in vertebroplasty: relationship with clinical outcome and complications. | prospective study. | 2011 | 21289575 |
| bilateral pars fractures complicating long fusion to l5 in a patient with rheumatoid arthritis. | case report. | 2011 | 21289579 |
| coagulation disorders in patients with locally advanced head and neck cancer - should they really be disregarded? | the aim of the study was to analyse coagulation disorders in patients with locally advanced cancer of the head and neck (chn)and with no other clinical cause for coagulation disorders treated with radiation therapy alone or concurrent chemoradiotherapy. we also assessed the duration of disorders in the course of therapy. the analysed group consisted of 33 patients with locally advanced chn documented as stage t3 or t4 acc. to the tnm classification. coagulology tests (activated partial thrombopl ... | 2011 | 21275462 |
| long-term stability after multilevel cervical laminectomy for spinal cord tumor resection in von hippel-lindau disease. | despite the frequent multiplicity and development of new spinal cord hemangioblastomas that require multiple resections in patients with von hippel-lindau (vhl) disease, the long-term effects of spinal surgery on spinal column stability in this neoplasia disorder are not known. to determine the effect of multilevel cervical laminectomy for spinal cord tumor resection in vhl, the authors analyzed long-term clinical and radiographic outcomes. | 2011 | 21275550 |
| cervical lymph node metastases in squamous cell carcinoma of tongue and floor of mouth. | oral squamous cell carcinoma has high chances of cervical lymph node metastasis. this case series describes the distribution of cervical lymph nodes in 50 cases of squamous cell carcinoma of tongue and floor of mouth. the mean age was 47.28±10.5 years. thirty positive metastatic lymph nodes were found; 90% occurring at level i-ii mostly in t4 size but also in t1 and t2 cases. the distribution of involved lymph nodes in oral cancer affects the neck dissection extent and is, therefore, an importan ... | 2011 | 21276390 |
| effect of whole pelvic radiotherapy for patients with locally advanced prostate cancer treated with radiotherapy and long-term androgen deprivation therapy. | purpose: to evaluate the effect of whole pelvic radiotherapy (wprt) in prostate cancer patients treated with rt and long-term (>1 year) androgen deprivation therapy (adt). methods and materials: prostate cancer patients with high-risk features (stage t3-t4 and/or gleason score =7 and/or prostate-specific antigen level =20 ng/ml) who had undergone rt and long-term adt were included in the present analysis. patients with bowel inflammatory disease, colon diverticula, and colon diverticulitis were ... | 2011 | 21277100 |
| laryngeal carcinoma metastasis to the orbit: case report. | we present the first report in the all english literature of a case of laryngeal squamous cell carcinoma metastasis to the orbit. | 2011 | 21269558 |
| targeted thyroid testing in acute illness - achieving success through audit. | thyroid tests are done in acutely ill patients who often have confusing transient thyroid abnormalities, despite a lack of clarity about intervention and cost benefit. a retrospective analysis of patients admitted to the medical assessment unit [mau] was undertaken in 2004 to assess the frequency and utility, pattern of abnormalities and cost of thyroid testing. guidelines were issued and the audit was repeated in 2008. 53.8% of 1593 were offered thyroid tests in 2004 with a significant reductio ... | 2011 | 21270508 |
| thoracic pedicle morphometry in different body-height population: a three dimensional study using reformatted computed tomography. | study design. a three-dimensional study of the thoracic pedicle (t1-t12) morphometry in chinese patients, with different body-height, using reformatted computed tomography.objective. to quantify the dimensions of the thoracic pedicles and to analyze the relationship between body-height and thoracic pedicle parameters.summary of background data. the thoracic pedicle morphometry has been studied extensively in different populations using various techniques. previous studies have shown a significan ... | 2011 | 21270680 |
| integrated analysis of the conformation of a protein-linked spin label by crystallography, epr and nmr spectroscopy. | long-range structural information derived from paramagnetic relaxation enhancement observed in the presence of a paramagnetic nitroxide radical is highly useful for structural characterization of globular, modular and intrinsically disordered proteins, as well as protein-protein and protein-dna complexes. here we characterized the conformation of a spin-label attached to the homodimeric protein cylr2 using a combination of x-ray crystallography, electron paramagnetic resonance (epr) and nmr spec ... | 2011 | 21271275 |
| thyroid hormones (t3 and t4): dual effect on human cancer cell proliferation. | several findings suggest that the patient's hormonal context plays a crucial role in determining cancer outcome. the exact nature of thyroid hormone action on tumour growth has not been established yet, in fact contrasting data show thyroid hormones have a promotory or an inhibitory action on cancer cell proliferation depending on the case. we hypothesized that not only tissue specificity, but also specific mutations occurring during tumoral development in different thyroid hormone cellular targ ... | 2011 | 21273585 |
| t2-t4 sympathectomy versus t3-t4 sympathicotomy for palmar and axillary hyperhidrosis. | to evaluate and compare the immediate and long-term outcomes of videothoracoscopic t2-t4 sympathectomy and t3-t4 sympathicotomy for the treatment of palmar and axillary hyperhidrosis. | 2011 | 21243401 |
| the prevalence of vertebral fractures and health-related quality of life in postmenopausal women. | vertebral fractures are the hallmark of osteoporosis, responsible for increased back pain, impairment of mobility and functional limitations. these factors have an impact on patients' health-related quality of life (qol). the aim of this study was to evaluate the prevalence of vertebral fractures in moroccan postmenopausal women and to assess their qol, using an arabic validated version of qualeffo. the study recruited 347 postmenopausal women in obvious good health. we excluded women who had us ... | 2011 | 21243498 |
| relevance of autoimmune thyroiditis in children and adolescents with vitiligo. | vitiligo is the most common pigmentation-related disorder worldwide. an autoimmune etiology is widely considered, and genetic factors may play an important role in its pathogenesis. the purpose of this study was to assess the incidence of thyroid dysfunctions and autoimmune thyroiditis in children with vitiligo and to identify related factors. | 2011 | 21244381 |
| foxp3 and survival in urinary bladder cancer. | objective: • to investigate the possible impact of foxp3 expression in t-cells, as well as in tumour cells, on long-term survival in patients with urinary bladder cancer (ubc) invading muscle. patients and methods: • in a retrospective study, tumour specimens from 37 patients cystectomized for t1-t4 ubc during 1999-2002 at the karolinska university hospital were examined by immunohistochemistry for tumour expression and/or infiltration of immune cells expressing foxp3 as well as cd3. • the resul ... | 2011 | 21244603 |
| endorectal ultrasound in rectal carcinoma--do the literature results really correspond to the realities of routine clinical care? | this multicenter, prospective, country-wide quality-assurance study at more than 300 hospitals in germany was designed to characterize and analyze the diagnostic accuracy of rectal endoscopic ultrasound (eus) in the routine clinical staging of rectal carcinoma (depth of tumor infiltration). | 2011 | 21234855 |
| thyroid status of space shuttle crewmembers: effects of iodine removal. | iodine is often used for water purification and has been used throughout the u.s. space program. because of concern about potential effects on crewmembers' thyroid function, in 1997 a system was implemented on board the space shuttles to remove iodine from water before it was consumed. we report here thyroid hormone data from crews flying before and after this system was implemented. | 2011 | 21235106 |
| plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of plasma-lyte 148 with a bicarbonate-balanced solution. | as even small concentrations of acetate in the plasma result in pro-inflammatory and cardiotoxic effects, it has been removed from renal replacement fluids. however, plasma-lyte 148 (plasma-lyte), an electrolyte replacement solution containing acetate plus gluconate is a common circuit prime for cardio-pulmonary bypass (cpb). no published data exist on the peak plasma acetate and gluconate concentrations resulting from the use of plasma-lyte 148 during cpb. | 2011 | 21235742 |
| immediate effects of the audible pop from a thoracic spine thrust manipulation on the autonomic nervous system and pain: a secondary analysis of a randomized clinical trial. | this study investigated the immediate effects of audible joint sounds following a supine t3-t4 spinal thrust manipulation on the autonomic nervous system activity using a fully automated pupillometry system in patients with chronic neck pain. an additional aim was to determine if audible sounds as perceived by the therapist were associated with the reduction of pain following manipulation. | 2011 | 21237406 |
| endonuclease vii is a key component of the mismatch repair mechanism in bacteriophage t4. | in previous papers we described an extra recombination mechanism in t4 phage, which contributed to general recombination only when particular mutations were used as geneticmarkers (high recombination or hr markers), whereas it was practically inactive towards other riib mutations (low recombination or lr markers). this marker-dependent recombination pathway was identified as a repair of mismatches in recombination heteroduplexes. we suggested that the first step in this pathway, recognition and ... | 2011 | 21237725 |