Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| linear and non-linear eeg analysis of adolescents with attention-deficit/hyperactivity disorder during a cognitive task. | we aimed to investigate whether electroencephalograph (eeg) dynamics differ in adolescents with attention-deficit/hyperactivity disorder (adhd) compared with healthy subjects during the performance of a cognitive task. | 2010 | 20659814 |
| [accuracy of perioperative cardiac preload monitoring by global end-diastolic volume and intrathoracic blood volume in orthotopic liver transplantation]. | to investigate the clinical value of global end-diastolic volume (gedv) and intrathoracic blood volume (itbv) in perioperative monitoring of the cardiac preload in patients undergoing orthotopic liver transplantations (olt). | 2010 | 20650770 |
| acid-base alterations during laparoscopic abdominal surgery: a comparison with laparotomy. | carbon dioxide insufflation during laparoscopic surgery results in an acid-base imbalance. the purpose of this study was to investigate the effect of pneumoperitoneum on the acid-base status using stewart's approach. | 2010 | 20650921 |
| [lung cancer from the perspective of internal medicine and surgery]. | in previous years numerous advances in diagnostics, staging and therapy of lung cancer have been achieved. nevertheless, it remains the most frequent cause of death from cancerous diseases. early diagnosis and exact staging enable multimodal therapy regimens adjusted to age and comorbidities, which result in complete remission in a few and in prolonged survival and good quality of life in most patients. curative surgery is possible in stage i non-small cell lung cancer (nsclc) and results in a 5 ... | 2010 | 20652215 |
| dermokine as a novel biomarker for early-stage colorectal cancer. | colorectal cancer is a common disease that is usually detected at an advanced stage, because early-stage cancer is mostly asymptomatic and appropriate serologic biomarkers have not been established. we have previously identified dermokine (dk) as a peptide secreted by keratinocytes and we found that dk-β/γ was expressed in colorectal tumors. therefore, we focused on dk-β/γ as a new candidate diagnostic serum marker for early colorectal cancer. | 2010 | 20652332 |
| efficacy of intrauterine lignocaine plus vaginal misoprostol for pain relief in premenopausal women undergoing endometrial aspiration and ambulatory hysteroscopy. | to compare the effectiveness of a combination of intrauterine lignocaine and vaginal misoprostol in reducing pain at hysteroscopy and endometrial aspiration (ea). | 2010 | 20590504 |
| reconstruction using free jejunal transfer after resection of cancer of the upper oesophagus. | treatment of cancer of the upper part of the oesophagus is challenging. even after intended curative treatment, less than half of the patients are alive after five years. this retrospective study evaluates all the patients who had the upper oesophagus reconstructed by use of a free jejunal transfer following cancer resection from february 2000 to may 2008 at the university hospital of aarhus. | 2010 | 20591339 |
| candidate dosimetric predictors of long-term swallowing dysfunction after oropharyngeal intensity-modulated radiotherapy. | to investigate long-term swallowing function in oropharyngeal cancer patients treated with intensity-modulated radiotherapy (imrt), and to identify novel dose-limiting criteria predictive for dysphagia. | 2010 | 20646872 |
| [effect of niobium nitride on the bonding strength of titanium porcelain by magnetron sputtering]. | to investigate the effect of magnetron sputtered niobium nitride (nbn) on the bonding strength of commercially pure cast titanium (ti) and low-fusing porcelain (ti/vita titankeramik system). | 2010 | 20654251 |
| igf-1 splice variant and igf-1 peptide expression patterns in young and old human skeletal muscle prior to and following sequential exercise bouts. | genes and proteins involved in insulin-like growth factor (igf)-1 signaling are thought to be differentially expressed in older versus younger mammalian skeletal muscle following acute exercise. the purpose of this study was to examine how multiple bouts of conventional resistance training meant to elicit hypertrophy affect the mrna expression of igf-1ea and igf-1ec (mgf) as well as the expression of total igf-1 peptides in human skeletal muscle. ten younger (18-25 years) and 10 older (60-75 yea ... | 2010 | 20668872 |
| [erythrocyte protective effects of ginaton in patients undergoing hypothermic cardiopulmonary bypass]. | to investigate the erythrocyte protective effects of ginaton, a ginkgo biloba extract, in patients undergoing hypothermic cardiopulmonary bypass (cpb). | 2010 | 20669670 |
| further decrease in glycated hemoglobin following ingestion of a lobag30 diet for 10 weeks compared to 5 weeks in people with untreated type 2 diabetes. | abstract: | 2010 | 20670414 |
| [acute renal failure in the course of hashimoto's thyroiditis]. | hashimoto's thyroiditis is the commonest form of autoimmune thyroiditis in the world. it occurs most frequently in women (female/male ratio, 6:1) in the age group between 30 and 60 years. here we report the case of a 38-year-old caucasian man who presented with a few days' history of upper limb paresthesias, widespread joint and muscle pain, and headaches. laboratory findings showed increased cpk, myoglobin and plasma creatinine levels with acute renal failure. low free t3 and t4 values associat ... | 2010 | 20672239 |
| validation of the 2009 tnm version in a large multi-institutional cohort of patients treated for renal cell carcinoma: are further improvements needed? | a new edition of the tnm was recently released that includes modifications for the staging system of kidney cancers. specifically, t2 cancers were subclassified into t2a and t2b (< or =10 cm vs >10 cm), tumors with renal vein involvement or perinephric fat involvement were classified as t3a cancers, and those with adrenal involvement were classified as t4 cancers. | 2010 | 20674150 |
| [evaluation of immediate breast reconstruction and radiotherapy: factors associated with complications]. | to determine prospectively the factors associated with reconstruction failure (i.e. requiring expander removal) and capsular contracture in patients undergoing mastectomy and immediate two-stage breast reconstruction with a tissue expander and implant, and radiotherapy for breast cancer. this is a multi-institutional prospective nonrandomized trial. | 2010 | 20674442 |
| neuropeptide coding of sympathetic preganglionic neurons; focus on adrenally projecting populations. | chemical coding of sympathetic preganglionic neurons (spn) suggests that the chemical content of subpopulations of spn can define their function. since neuropeptides, once synthesized are transported to the axon terminal, most demonstrated chemical coding has been identified using immunoreactive terminals at the target organ. here, we use a different approach to identify and quantify the subpopulations of spn that contain the mrna for pituitary adenylate cyclase activating polypeptide (pacap) or ... | 2010 | 20674686 |
| ischemia-reperfusion histopathology alterations of the rabbit intestinal wall with and without exclusion of the collateral mesenteric circulation supply. | to evaluate the histopathology alterations of the intestinal mucosa of rabbits submitted to different times of mesenteric artery ischemia and reperfusion with and without celiac artery collateral circulation supply. | 2010 | 20676487 |
| predictors of postoperative survival in patients with locally advanced non-small cell lung carcinoma. | a surgical resection for locally advanced non-small cell lung carcinoma (nsclc) remains controversial. this study analyzed the clinicopathological profile and surgical outcome of patients with locally advanced nsclc to identify the predictors of survival. | 2010 | 20676855 |
| surgical therapeutic strategy for non-small cell lung cancer with mediastinal lymph node metastasis (n2). | approximately 30% of patients who are diagnosed with non-small cell lung cancer (nsclc) are classified as n2 on the basis of metastasis to the mediastinal lymph nodes. the effectiveness of surgery for these patients remains controversial. although surgeries in recent years are proved to be effective to some extent, yet due to many reasons, 5-year survival rate after surgery varies greatly from patient to patient. thus it is necessary to select patients who have a high probability of being be cur ... | 2010 | 20677562 |
| pulpal blood flow changes due to rapid maxillary expansion. | to determine the pulpal blood flow (pbf) changes in anchorage teeth associated with the high forces of a rapid maxillary expansion (rme) appliance. | 2010 | 20677966 |
| mice deficient in mct8 reveal a mechanism regulating thyroid hormone secretion. | the mechanism of thyroid hormone (th) secretion from the thyroid gland into blood is unknown. humans and mice deficient in monocarboxylate transporter 8 (mct8) have low serum thyroxine (t4) levels that cannot be fully explained by increased deiodination. here, we have shown that mct8 is localized at the basolateral membrane of thyrocytes and that the serum th concentration is reduced in mct8-ko mice early after being taken off a treatment that almost completely depleted the thyroid gland of th. ... | 2010 | 20679730 |
| the value of clinical prognostic factors for survival in patients with invasive urinary bladder cancer. | the aim of the study was to evaluate the value of clinical prognostic factors for survival of patients with invasive urinary bladder cancer treated with radical cystectomy, chemotherapy, and radiotherapy. | 2010 | 20679745 |
| largest molecular clusters in the supertetrahedral tn series. | supertetrahedral tn clusters are exact fragments of cubic zns-type lattice and are often formed in situ as building units for the construction of 3-d open-framework chalcogenide materials. small tn clusters can also be synthesized in discrete forms, allowing them to exist as soluble species in solution. in addition to their tunable electronic and optical properties, these soluble clusters can be used as precursors for the synthesis of porous semiconducting and optical materials. however, the syn ... | 2010 | 20681716 |
| prolonged jaundice in newborns is associated with low antioxidant capacity in breast milk. | in breastfeeding newborns who are otherwise healthy, the mechanism of prolonged jaundice remains unclear. the aim of this study was to investigate relations between prolonged jaundice and oxidative parameters in breast milk. full-term, otherwise healthy newborns with jaundice lasting more than 2 weeks were enrolled prospectively in the study. as a control group, newborns in the same age group but without prolonged jaundice were selected. all newborns in the study were exclusively breastfed. in t ... | 2010 | 20681927 |
| reparation of chlorpyrifos-induced impairment by thyroxine and vitamin c in fish. | the organophosphate pesticide chlorpyrifos significantly decreased the specific activities of catalase (cat) and lactate dehydrogenase (ldh) in brain, liver, gill and skeletal muscle of the freshwater catfish, heteropneustes fossilis. it may be due to binding of the pesticide or its metabolite(s) with the enzyme molecules or affecting the synthesis and/or degradation of the enzymes. rna and protein content also declined significantly in different tissues of the fish in response to chlorpyrifos, ... | 2010 | 20684993 |
| construction of robust bio-nanotubes using the controlled self-assembly of component proteins of bacteriophage t4. | 2010 | 20661999 | |
| low-level laser therapy in chronic autoimmune thyroiditis: a pilot study. | chronic autoimmune thyroiditis (cat) remains the most common cause of acquired hypothyroidism. there is currently no therapy that is capable of regenerating cat-damaged thyroid tissue. the objective of this study was to gauge the value of applying low-level laser therapy (lllt) in cat patients based on both ultrasound studies (uss) and evaluations of thyroid function and thyroid autoantibodies. | 2010 | 20662037 |
| the evaluation of the adrenal and thyroid axes and glucose metabolism after burn injury in children. | burn injury is an important trauma and can cause many hormonal and metabolic changes in the human body. in contrast to the situation with adults, there are inadequate number of studies on children with this condition. our aim in this study was to determine the changes in the adrenal, thyroid axes and glucose metabolism in the acute and subacute period and relation to the percent total body surface area (tbsa) burned in children with major burn injury. | 2010 | 20662347 |
| genomic analysis of oceanic cyanobacterial myoviruses compared with t4-like myoviruses from diverse hosts and environments. | t4-like myoviruses are ubiquitous, and their genes are among the most abundant documented in ocean systems. here we compare 26 t4-like genomes, including 10 from non-cyanobacterial myoviruses, and 16 from marine cyanobacterial myoviruses (cyanophages) isolated on diverse prochlorococcus or synechococcus hosts. a core genome of 38 virion construction and dna replication genes was observed in all 26 genomes, with 32 and 25 additional genes shared among the non-cyanophage and cyanophage subsets, re ... | 2010 | 20662890 |
| [construction of eukaryote expression vector carrying human pulmonary surfactant-associated protein c and its expression in vitro]. | to clone human pulmonary surfactant-associated protein c (sp-c) and construct an eukaryote expression vector pcdna3.1(+)/sp-c, and then to examine the sp-c expression in vitro, which may provide a reliable way of massive production of sp-c. | 2010 | 20663299 |
| functional paragangliomas of the urinary bladder: a report of 9 cases. | functional paraganglioma of the urinary bladder (fpub) is a rare tumor. misdiagnosis of fpub before operation can lead to serious intraoperative consequences. in this article, we reported our experience in preoperative diagnosis and surgical treatment of fpub. | 2010 | 20663319 |
| postoperative radiotherapy improved survival of poor prognostic squamous cell carcinoma esophagus. | the purpose of this study was identify prognostic factors and to investigate the association between postoperative radiotherapy and overall survival of thoracic esophageal squamous cell carcinoma patients. | 2010 | 20667325 |
| molecular characterization and gene expression of thyrotropin receptor (tshr) and a truncated tshr-like in senegalese sole. | thyroid hormones (ths) play a key role in larval development, growth and metamorphosis in flatfish. their synthesis is tightly regulated by the hypothalamic-pituitary-thyroid axis. thyroid-stimulating hormone receptor (tshr) is a key protein in the control of thyroid function stimulating th synthesis after binding its ligand, the thyrotropin. in teleost fish, numerous reports have associated the tshr with gametogenesis. however, little information about its role during larval development is avai ... | 2010 | 20685365 |
| a specific docking site for dna polymerase {alpha}-primase on the sv40 helicase is required for viral primosome activity, but helicase activity is dispensable. | replication of simian virus 40 (sv40) dna, a model for eukaryotic chromosomal replication, can be reconstituted in vitro using the viral helicase (large tumor antigen, or tag) and purified human proteins. tag interacts physically with two cellular proteins, replication protein a and dna polymerase α-primase (pol-prim), constituting the viral primosome. like the well characterized primosomes of phages t7 and t4, this trio of proteins coordinates parental dna unwinding with primer synthesis to ini ... | 2010 | 20685648 |
| critical analysis of mucin and signet ring cell as prognostic factors in an asian population of 2,764 sporadic colorectal cancers. | conflicting data on the clinicopathological characteristics as well as prognosis and survival of signet ring cell (src) and mucinous adenocarcinomas (ma) of the colorectum persist. | 2010 | 20686777 |
| neuroendocrine dysfunction in patients recovering from subarachnoid hemorrhage. | subarachnoid hemorrhage (sah) is a recently identified risk factor for hypopituitarism, particularly growth hormone (gh) and corticotrophins deficiencies. the aim of our study was to identify possible predictor(s) for neuroendocrine dysfunction in sah survivors. | 2010 | 20688621 |
| combined therapy with l-thyroxine and l-triiodothyronine compared to l-thyroxine alone in the treatment of primary hypothyroidism. | the objective of this study was to compare various parameters in patients with hypothyroidism receiving either monotherapy with l-thyroxine (l-t4) or combination therapy with l-t4 and l-triiodothyronine (l-t3). | 2010 | 20688622 |
| relationship between serum zinc levels, thyroid hormones and thyroid volume following successful iodine supplementation. | zinc is essential for many biochemical processes and also for cell proliferation. thyroid hormones influence zinc metabolism by affecting zinc absorption and excretion. additionally, zinc deficiency affects thyroid function. the aim of the present study was to evaluate a possible association of zinc levels with thyroid volume, thyroid hormones and thyroid autoantibody levels in healthy subjects, patients with autoimmune thyroid disease (aitd) and patients with nodular goitre following successful ... | 2010 | 20688624 |
| the emergence of translational epidemiology: from scientific discovery to population health impact. | recent emphasis on translational research (tr) is highlighting the role of epidemiology in translating scientific discoveries into population health impact. the authors present applications of epidemiology in tr through 4 phases designated t1-t4, illustrated by examples from human genomics. in t1, epidemiology explores the role of a basic scientific discovery (e.g., a disease risk factor or biomarker) in developing a "candidate application" for use in practice (e.g., a test used to guide interve ... | 2010 | 20688899 |
| invited commentary: the epicenter of translational science. | epidemiology is at the center of translational science. uniquely among biomedical disciplines, the methods and perspective of epidemiology span research from discovery to effective interventions and ultimately to their dissemination and implementation. however, shorthand designations for various phases of translational science, such as "t1, t2, t3, and t4," may be proliferating past the level of their usefulness. it is worthwhile to reflect on the actual nature of the science undertaken by epide ... | 2010 | 20688901 |
| adipocyte-myocyte crosstalk in skeletal muscle insulin resistance; is there a role for thyroid hormone? | to review original research studies and reviews that present data on adipocyte-myocyte crosstalk in the development of skeletal muscle insulin resistance with a specific focus on thyroid hormone. | 2010 | 20689414 |
| the effect of milrinone infusion on right ventricular function during coronary anastomosis and early outcomes in patients undergoing off-pump coronary artery bypass surgery. | during coronary anastomosis in off-pump coronary artery bypass surgery (opcab), hemodynamic alternations can be induced by impaired diastolic function of the right ventricle. this study was designed to examine the effect of milrinone on right ventricular function and early outcomes in patients undergoing opcab. | 2010 | 20740213 |
| molecular alterations in key-regulator genes among patients with t4 breast carcinoma. | prognostic factors in patients who are diagnosed with t4 breast carcinomas are widely awaited. we here evaluated the clinical role of some molecular alterations involved in tumorigenesis in a well-characterized cohort of t4 breast cancer patients with a long follow-up period. | 2010 | 20735841 |
| contemporary management of sinonasal cancer. | background.: sinonasal cancer is a relatively uncommon entity encountered by head and neck oncologists, rhinologists, and skull base surgeons. recent innovations in surgical and nonsurgical therapeutic modalities raise the question of whether there has been any measurable improvement for treatment outcomes. methods.: a retrospective review of data from recent studies that focus on surgery, radiation, and chemotherapy, or combinations thereof, was conducted. results.: surgery continues to be the ... | 2010 | 20737500 |
| evaluation of the seventh american joint committee on cancer/international union against cancer classification of gastric adenocarcinoma in comparison with the sixth classification. | the seventh tnm staging system for gastric cancer of the american joint committee on cancer/international union against cancer (ajcc/uicc) had a more detailed classification than the sixth tnm staging system for both the tumor (t) and lymph nodes (n). the authors compared survival rates assessed by the seventh staging system with those by the sixth system. | 2010 | 20737569 |
| complete mapping of glomeruli based on sensory nerve branching pattern in the primary olfactory center of the cockroach periplaneta americana. | glomeruli are structural and functional units in the primary olfactory center in vertebrates and insects. in the cockroach periplaneta americana, axons of different types of sensory neurons housed in sensilla on antennae form dorsal and ventral antennal nerves and then project to a number of glomeruli. in this study, we identified all antennal lobe (al) glomeruli based on detailed innervation patterns of sensory tracts in addition to the shape, size, and locations in the cockroach. the number of ... | 2010 | 20737592 |
| thyroid hormones profile in students of makerere college of health sciences in kampala uganda. | serum concentrations of thyroxine (t4), triiodothyronine (t3) and thyroid stimulating hormone (tsh) are used to assess thyroid function. it is recommended that each laboratory or hospital should establish its own reference values of t4, t3 and tsh for their clients because these hormones vary with ethnicity, geographical and climatic conditions of a population. there is no documented study which has been done to determine the thyroid hormones profile in ugandan general population. this study is ... | 2010 | 20737825 |
| long-term parental psychological distress among parents of children with a malformation--a prospective longitudinal study. | we previously reported that prenatal diagnosis of malformations is associated with increased parental psychological distress after birth compared to distress in parents with postnatal diagnosis. we have now extended our earlier study to include a long-term follow-up of mothers and fathers 9 years after birth. psychological responses were measured by general health questionnaire (ghq-28), state anxiety inventory (stai-x1), and impact of event scale (ies) in 118 mothers and 100 fathers of 124 chil ... | 2010 | 20803642 |
| reduction of bupivacaine dose in spinal anaesthesia for caesarean section may improve maternal satisfaction by reducing incidence of low blood pressure episodes. | spinal anaesthesia for caesarean section exposes to high incidence of arterial hypotension which can result in maternal and neonatal morbidity. we hypothesized that the reduction of this dose from 10 mg to 7.5 mg would minimize hypotension without altering pain relief. | 2010 | 20803855 |
| can bone loss be reversed by antithyroid drug therapy in premenopausal women with graves' disease? | abstract: | 2010 | 20807449 |
| plasma zinc, copper, and serum thyroid hormones and insulin levels after zinc supplementation followed by placebo in competitive athletes. | intense physical activity is associated with biological adaptations involving hormones and trace elements. zinc supplementation may affect plasma copper concentration, thyroid-stimulating hormone (tsh), thyroid hormones, insulin, and glucose homeostasis, but data in athletes are scarce. the aim of this study was to evaluate in competitive athletes (cyclists, n = 7, 32 +/- 8 years) the effect of zinc supplementation (22 mg/day as zinc gluconate) during 30 days, and discontinuation using placebo ( ... | 2010 | 20809272 |
| [new tnm classification of malignant lung tumours]. | the staging system for lung tumours is now recommended for the classification of both non-small-cell and small-cell lung cancer as well as for carcinoid tumours of the lung. the t classifications have been redefined: t1 has been subclassified as t1a (≤ 2 cm in size) and t1b (> 2-3 cm in size). t2 has been subclassified as t2a (> 3-5 cm in size) and t2b (> 5-7 cm in size). t2 (> 7 cm in size) has been reclassified as t3. multiple tumour nodules in the same lobe have been reclassified from t4 to t ... | 2010 | 20809404 |
| prognostic relevance of bmi-1 expression and autoantibodies in esophageal squamous cell carcinoma. | overexpression of bmi-1 has been observed in a variety of cancers, and it has been suggested to be an independent prognostic marker for the patients. the objective of this study was to determine the level of bmi-1 expression or its autoantibodies in human esophageal squamous cell carcinoma (escc) and to correlate it with clinicopathologic data. | 2010 | 20809956 |
| normal cortisol response on low-dose synacthen (1 microg) test in children with prader willi syndrome. | it has been postulated that central adrenal insufficiency (cai), resulting from hypothalamic dysfunction, may contribute to the increased unexplained death rates in prader willi syndrome (pws). a study using the overnight metyrapone test reported a 60% prevalence of cai in children with pws. we used a low-dose synacthen test to screen for cai in children with pws. | 2010 | 20810574 |
| template-directed ligation of tethered mononucleotides by t4 dna ligase for kinase ribozyme selection. | in vitro selection of kinase ribozymes for small molecule metabolites, such as free nucleosides, will require partition systems that discriminate active from inactive rna species. while nucleic acid catalysis of phosphoryl transfer is well established for phosphorylation of 5' or 2' oh of oligonucleotide substrates, phosphorylation of diffusible small molecules has not been demonstrated. | 2010 | 20811490 |
| waiting time for emergency abdominal surgery in zaria, nigeria. | management of surgical emergencies in nigeria is characterised by mismatch between supply of facilities and demand for care. this study aimed to evaluate the waiting time between presentation at hospital with acute abdominal disease and operative intervention. | 2010 | 20811524 |
| novel bladder preservation therapy for locally invasive bladder cancer: combined therapy using balloon-occluded arterial infusion of anticancer agent and hemodialysis with concurrent radiation. | we investigated the effect of balloon-occluded arterial infusion (boai) of anticancer agent (cisplatin/gemcitabine), used concomitantly with hemodialysis, which delivers an extremely high concentration of anticancer agent to the site of a tumor without systemic adverse effects, along with concurrent radiation (referred to as the omc-regimen) in patients with advanced bladder cancer. one hundred and ninety-two patients were assigned to receive either the omc-regimen (n=96) or total cystectomy (n= ... | 2010 | 20811698 |
| predicting factors of unexpected peritoneal seeding in locally advanced gastric cancer: indications for staging laparoscopy. | the aim of this study is to investigate predictive factors for unexpected peritoneal seeding from clinically resectable advanced gastric cancers to suggest the indications for staging laparoscopy (sl). | 2010 | 20812349 |
| [effect of intravenous lornoxicam at different doses on the immune function in patients undergoing total abdominal hysterectomy]. | to investigate the effect of intravenous lornoxicam (lor) at different doses given preoperatively on the immune function of patients undergoing total abdominal hysterectomy (tah). | 2010 | 20813681 |
| nanopore analysis of tethered peptides. | peptides of 12 amino acids were tethered via a terminal cysteine to mono-, di-, tri-, and tetrabromomethyl-substituted benzene to produce bundles of one to four peptide strands (cy12-t1 to cy12-t4, respectively). the interaction of the bundles with the α-hemolysin pore was assessed by measuring the blockade currents (i) and times (t) at an applied potential of - 50, - 100, and - 150 mv. three types of events could be distinguished: bumping events, with small i and short t where the molecule tran ... | 2010 | 20814890 |
| changes in serum tsh and free t4 during human sleep restriction. | to examine whether recurrent sleep restriction is accompanied by changes in measures of thyroid function. | 2010 | 20815195 |
| [exploration of the classification of gross tumor volume and pathological staging of esophageal carcinoma]. | using the volume calculating function of treatment planning system of 3dcrt to work out the value of gtv standard classifications and to provide the reference for clinical staging of esophageal carcinoma. | 2010 | 20819484 |
| polyhalogenated aromatic hydrocarbons and metabolites: relation to circulating thyroid hormone and retinol in nestling bald eagles (haliaeetus leucocephalus). | polyhalogenated aromatic hydrocarbons are global contaminants that are often considered to be endocrine disruptors and include 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (p,p'-dde), polychlorinated biphenyls (pcbs), and polybrominated diphenyl ethers (pbdes). the present study examined these compounds and their hydroxylated metabolites or analogues and relationships with circulating thyroid hormones and retinols in plasma from nestling and adult bald eagles in british columbia, canada, and cal ... | 2010 | 20821573 |
| dioxin-like and perfluorinated compounds in pigs in an indian open waste dumping site: toxicokinetics and effects on hepatic cytochrome p450 and blood plasma hormones. | dioxins and related compounds (drcs) and perfluorinated compounds were measured in the livers of pigs (sus scrofa) collected from an open waste dumping site in south india. hepatic concentrations of drcs and perfluorooctanesulfonate (pfos; up to 200 ng/g wet wt) were significantly higher in male and female pigs, respectively, collected from the dumping site than in those from a reference site. results suggest that dumping sites are a source of drcs and pfos. hepatic concentrations of drcs in pig ... | 2010 | 20821605 |
| sympathetic vasoconstriction is potentiated in arteries caudal but not rostral to a spinal cord transection in rats. | sympathetic nerve-mediated contractions of mesenteric and tail arteries controlled by preganglionic neurones decentralized by a spinal cord injury (sci) are potentiated, and likely contribute to autonomic dysreflexia. however, reactivity to the α(1)-adrenoceptor agonist phenylephrine has been reported to be enhanced in vascular beds controlled by preganglionic neurones lying both rostral and caudal to an sci in vivo. here responses of isometrically-mounted median and saphenous arteries isolated ... | 2010 | 20822463 |
| measurement of thyroid hormones in donkey (equus asinus) blood and milk: validation of elisa kits and evaluation of sample collection, handling and storage. | donkey's milk is well tolerated by human infants with cow's milk allergy and is useful in the treatment of human immune-related diseases and in the prevention of atherosclerosis. thyroid hormones (th) stimulate lactation and active triiodothyronine (t3) in colostrum and milk could take paracrine action supporting lactogenesis in the mother, and play physiological roles for the suckling offspring (systemic or within the gastrointestinal tract). the aims were to measure th concentrations in donkey ... | 2010 | 20822570 |
| [microsatellite instability. a new predictive marker (?)]. | microsatellite instability (msi) is a hallmark of hereditary non-polyposis colorectal cancer (hnpcc), but also occurs in about 12%-15% of sporadic colorectal cancer (crc) where it is a consequence of an epigenetic inactivation of mlh1. high frequency msi (msi-h; i.e. at least two of five specified microsatellite markers show instability) was shown in a large meta-analysis and in recent trials to be a positive prognostic marker for overall survival in crc. msi-h or mismatch repair deficiency (mmr ... | 2010 | 20824433 |
| prevalence of goitre in isfahan, iran, fifteen years after initiation of universal salt iodization. | this cross-sectional study investigated the prevalence of goitre in isfahan, a centrally-located city in iran, 15 years after the initiation of universal salt iodization. in total, 2,523 isfahani adults (1,275 males, 1,248 females) aged > 20 years were selected by multi-stage cluster-sampling method. goitre rate, serum thyroid-stimulating hormone (tsh), thyroxine (t4), thyroid peroxidase antibody (tpoab), thyroglobulin antibody (tgab), and urinary iodine concentration (uic) were measured and com ... | 2010 | 20824978 |
| correlation between eeg abnormalities and symptoms of autism spectrum disorder (asd). | children with asd often suffer from epilepsy and paroxysmal eeg abnormality. purposes of this study are the confirmation of incidence of epileptic seizures and eeg abnormalities in children with autism using a high performance digital eeg, to examine the nature of eeg abnormalities such as locus or modality, and to determine if the development of children with asd, who have experienced developmental delay, improves when their epilepsy has been treated and maintained under control. a total of 101 ... | 2010 | 20826075 |
| a locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study. | thyroid hormones are key regulators of cellular growth, development, and metabolism, and thyroid disorders are a common cause of ill health in the community. circulating concentrations of thyrotropin (tsh), thyroxine (t4) and triiodothyronine (t3) have a strong heritable component and are thought to be under polygenic control, but the genes responsible are mostly unknown. in order to identify genetic loci associated with these metabolic phenotypes, we performed a genome-wide association study of ... | 2010 | 20826269 |
| expression of peptidylarginine deiminase type 4 in ovarian tumors. | peptidylarginine deiminase type 4 (padi4) converts arginine residues into citrulline. the current study focused on the expression of padi4 in various subtypes of ovary cancers, and this study investigated the effects of estrogen on padi4 expression in skov-3 cells that originated from ovary tumors. we utilized immunohistochemistry, real-time pcr and western blotting to analyze the expression of padi4 in the tumor tissues and in the cell line that were cultured with estrodial-17β. padi4 was detec ... | 2010 | 20827398 |
| autonomic dysreflexia-like syndrome in a t12 paraplegic during thoracic spine surgery. | a 19-year-old african american man with a t12 spinal cord lesion underwent a t4-l5 thoracolumbar spinal fusion. intraoperatively, his arterial blood pressure acutely increased from 110/60 to 260/130 mm hg without a change in heart rate. the patient did not have pheochromocytoma, carcinoid syndrome, or thyroid storm. this presentation differs from autonomic dysreflexia because the spinal cord lesion was well below t6, hypertension was elicited with somatic stimulation above the lesion, and the re ... | 2010 | 20829560 |
| programmed cell death 4 loss increases tumor cell invasion and is regulated by mir-21 in oral squamous cell carcinoma. | abstract: | 2010 | 20831814 |
| pretreatment apparent diffusion coefficient of the primary lesion correlates with local failure in head-and-neck cancer treated with chemoradiotherapy or radiotherapy. | purpose: this study was performed to evaluate whether the apparent diffusion coefficient (adc) of a primary lesion correlates with local failure in primary head-and-neck squamous cell carcinoma (hnscc) treated with chemoradiotherapy or radiotherapy. methods and materials: we retrospectively studied 38 patients with primary hnscc (12 oropharynx, 20 hypopharynx, 4 larynx, 2 oral cavity) treated with chemoradiotherapy or radiotherapy with radiation dose to gross tumor volume equal to or over 60 gy ... | 2010 | 20832179 |
| lymphocyte sub-population cell counts are associated with the metabolic syndrome and its components in the vietnam experience study. | the metabolic syndrome (mets) increases the risk of cardiovascular disease morbidity and mortality. mets is also associated with increases in the number of circulating white blood cells. lymphocyte sub-population counts have also been implicated in cardiovascular disease; this analysis will examine whether or not they are associated with mets. | 2010 | 20833394 |
| the effect of adding magnesium sulphate to epidural bupivacaine and fentanyl in elective caesarean section using combined spinal-epidural anaesthesia: a prospective double blind randomised study. | combined spinal-epidural anaesthesia is commonly used for elective caesarean section. intrathecal injection produces rapid onset with minimal doses of local anaesthetic and epidural administration can be used to prolong the block. our study examined the effects of adding magnesium sulphate to epidural bupivacaine and fentanyl in patients undergoing elective caesarean section using combined spinal-epidural anaesthesia. | 2010 | 20833531 |
| lung cancer staging essentials: the new tnm staging system and potential imaging pitfalls. | lung cancer is the leading cause of cancer-related deaths worldwide, with a dismal 5-year survival rate of 15%. the tnm (tumor-node-metastasis) classification system for lung cancer is a vital guide for determining treatment and prognosis. despite the importance of accuracy in lung cancer staging, however, correct staging remains a challenging task for many radiologists. the new 7th edition of the tnm classification system features a number of revisions, including subdivision of tumor categories ... | 2010 | 20833843 |
| response of eucalyptus camaldulensis to irrigation with the hudiara drain effluent. | a pot experiment was conducted to evaluate the effects of the industrial effluent of the hudiara drain on the growth and element accumulation by eucalyptus camaldulensis at early growth stage. plants were irrigated for 18 months with effluent diluted with tap water at 0% (t0), 25% (t1), 50% (t2), 75% (t3), and 100% effluent (t4). results showed that the maximum growth in terms of stem height (260 cm), number of branches (29), stem fresh weight (436.67 g), stem dry weight (203.33 g), total seedli ... | 2010 | 20734912 |
| gigantic two-photon absorption cross sections and strong two-photon excited fluorescence in pyrene core dendrimers with fluorene/carbazole as dendrons and acetylene as linkages. | we report a series of stiff dendrimers (referred to as t1, t2, t3, and t4) that have both gigantic two-photon absorption (tpa) cross sections up to 25,000 gm and strong two-photon excited fluorescence (tpef) with fluorescence quantum yield of ∼0.5. the large tpa cross sections and high quantum yields of these dendrimers are directly related to their geometrical structures, where the polycyclic aromatic pyrene is chosen as the chromophoric core because of its planar and highly π-conjugated struct ... | 2010 | 20735053 |
| virus silicification under simulated hot spring conditions. | silicification of organisms in silica-depositing environments can impact both their ecology and their presence in the fossil record. although microbes have been silicified under laboratory and environmental conditions, viruses have not. bacteriophage t4 was successfully silicified under laboratory conditions that closely simulated those found in silica-depositing hot springs. virus morphology was maintained, and a clear elemental signature of phosphorus was detected by energy-dispersive x-ray sp ... | 2010 | 20735248 |
| [tnm classification of breast cancer: changes and comments on the 7th edition]. | the 7th edition of the tnm classification includes only minor changes in the main tnm categories for breast cancer. only ductal and lobular carcinoma in situ (dcis, lcis), and isolated paget's disease of the nipple are classified as ptis, but not precursor lesions such as atypical ductal or lobular hyperplasia (adh, alh). ajcc emphasizes that microscopic measurement is the most accurate and preferred method to determine pt in small invasive cancers and stresses the importance of strict adherence ... | 2010 | 20711589 |
| [modified primary stable ventral derotation spondylodesis with halm-zielke instrumentation for the treatment of idiopathic scoliosis]. | surgical technique with an anterior double-rod system for thoracic, thoracolumbar, or lumbar scoliosis. the aim of the system is to correct the coronal plane deformity and normalize the sagittal balance. | 2010 | 20711827 |
| deficits in bladder function following spinal cord injury vary depending on the level of the injury. | loss of bladder function is an important consequence of a spinal cord injury (sci) but is rarely assessed in animal studies of sci. here, we use a simple outcome measure (volume of retained urine) to assess bladder dysfunction over time following moderate contusion injuries at 3 different thoracic levels (t1, t4, or t9) and complete crush injuries (t1 vs. t9). the volume of urine retained in the bladder was measured daily for fourteen days post injury by anesthetizing the animals with isoflurane ... | 2010 | 20713043 |
| allan-herndon-dudley syndrome (ahds) caused by a novel slc16a2 gene mutation showing severe neurologic features and unexpectedly low trh-stimulated serum tsh. | thyroid hormones are known to be essential for growth, development and metabolism. recently mutations in the slc16a2 gene coding for the monocarboxylate thyroid hormone transporter 8, mct8, have been associated with allan-herndon-dudley syndrome (ahds), an x-linked condition characterized by severe mental retardation, dysarthria, athetoid movements, muscle hypoplasia and spastic paraplegia. here we describe in detail the clinical and biochemical features in a boy affected by ahds with severe neu ... | 2010 | 20713192 |
| molecular-genetic identification of t4 bacteriophages in lake baikal. | 2010 | 20714850 | |
| prognostic factors for patients after curative resection for proximal gastric cancer. | the factors influencing the long-term survival of patients with proximal gastric cancer (pgc) after curative resection were investigated. data from 171 patients who underwent curative resection for pgc were retrospectively analyzed. the patients were grouped according to the clinicopathological factors and operative procedures. the tumor depth (t stage) and lymph node metastasis (pn stage) were graded according to the fifth edition of tnm staging system published by uicc in 1997. the metastatic ... | 2010 | 20714884 |
| [technical pitfalls of pleural dissection in extrapleural pneumonectomy]. | because extrapleural pneumonectomy (epp) for malignant pleural mesothelioma (mpm) suffers from unsatisfiable risk/benefit ratio, very careful consideration on its indication should be required. epp is a complicated, multi-step surgery that includes pleural dissection, division of hilum, resection of a block of pleura, lung, diaphragm and pericardium, and reconstruction of diaphragm and pericardium. therefore establishment of surgical images of whole procedures before starting surgery is essentia ... | 2010 | 20715442 |
| early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. | hypopituitary ames dwarf mice were injected either with growth hormone (gh) or thyroxine for a 6-wk period to see whether this intervention would reverse their long life span or the resistance of their cells to lethal stresses. ames dwarf mice survived 987 ± 24 d (median), longer than nonmutant control mice (664 ± 48), but gh-injected dwarf mice did not differ from controls (707 ± 9). fibroblast cells from ames dwarf mice were more resistant to cadmium than cells from nonmutant controls (ld(50) ... | 2010 | 20720157 |
| [the current tnm system for gastrointestinal tumors part i]. | the present review describes the changes in the new 7th edition of the tnm system for tumors of the upper gastrointestinal tract. the description of esophageal tumor localization has been simplified and this new classification now includes tumors of the esophagogastric junction as well as the proximal 5 cm of the stomach. the regional lymph nodes of the esophagus now include celiac lymph nodes, a change which is important for therapeutic decision making. the categories t1 and t4 have been furthe ... | 2010 | 20721558 |
| surgical correction of spinal deformity in patients with congenital muscular dystrophy. | congenital muscular dystrophy (cmd), among the myopathic disorders is one form of flaccid neuromuscular disorder (nmd). patients with nmd frequently develop progressive spinal deformity. for nmd patients who have a severe spinal deformity, sitting is often difficult and is accompanied by pain and breakdown of the skin. spinal deformity surgery in these patients has been highly effective in stabilizing the spine, maintaining upright, comfortable sitting balance, and improving patients' quality of ... | 2010 | 20721717 |
| nonsurgical innovations in the treatment of nonmelanoma skin cancer. | basal cell carcinoma and squamous cell carcinoma are the most frequent types of cancer in the united states and represent 75 percent and 20 percent, respectively, of all nonmelanoma skin cancers. since ultraviolet radiation is implicated in their development, photoprotection is fundamental in their prevention. additional preventive measures include identifying high-risk individuals for early detection along with using agents, such as retinoids, that are effective in decreasing the risk of premal ... | 2010 | 20725548 |
| cranio-thoracic bullet migration over a period of 27 years: case report. | we report the case of a 36 year old woman that was hurt in the head with a lost bullet while walking through the street when she was 9 years old. on admission, the patient was fully conscious with no neurological deficits. skull radiography showed the intracranial bullet but she was dispatched after 24 hours of observation without neurological deterioration. six months later she suddenly presented quadriplegia and after one year of rehabilitation she recovered the mobility and strength in all he ... | 2010 | 20725703 |
| anastomotic leak rate after low anterior resection for rectal cancer after chemoradiation therapy. | anastomotic leak may be the most concerning complication after colorectal anastomosis. to compare open with laparoscopic rectal resection, we must have accurate leak rates in patients who have received neoadjuvant chemoradiation therapy to serve as a benchmark for comparison. all patients who had preoperative chemoradiation therapy with rectal resection and low pelvic anastomosis for cancer in a single colorectal practice over a 7-year period were retrospectively reviewed. all patients had proxi ... | 2010 | 20726419 |
| combination of dna ligase reaction and gold nanoparticle-quenched fluorescent oligonucleotides: a simple and efficient approach for fluorescent assaying of single-nucleotide polymorphisms. | a new fluorescent sensing approach for detection of single-nucleotide polymorphisms (snps) is proposed based on the ligase reaction and gold nanoparticle (aunps)-quenched fluorescent oligonucleotides. the design exploits the strong fluorescence quenching of aunps for organic dyes and the difference in noncovalent interactions of the nanoparticles with single-stranded dna (ssdna) and double-stranded dna (dsdna), where ssdna can be adsorbed onto the surface of aunps while dsdna cannot be. in the a ... | 2010 | 20726510 |
| inverse expression of estrogen receptor-beta and nuclear factor-kappab in urinary bladder carcinogenesis. | to investigate the expression of nuclear factor-kappab (nf-kappab) and estrogen receptor-beta (er-beta) signalling pathways in bladder urothelial carcinoma according to clinicopathological features, in order to elucidate their role during carcinogenesis. | 2010 | 20727050 |
| implications of overweight in gastric cancer: a multicenter study in a western patient population. | the purpose of this study was to evaluate the effects of overweight on surgical and long-term outcomes in a western population of patients with gastric cancer (gc). | 2010 | 20727706 |
| a mutation within the β subunit of escherichia coli rna polymerase impairs transcription from bacteriophage t4 middle promoters. | during infection of escherichia coli, bacteriophage t4 usurps the host transcriptional machinery, redirecting it to the expression of early, middle, and late phage genes. middle genes, whose expression begins about 1 min postinfection, are transcribed both from the extension of early rna into middle genes and by the activation of t4 middle promoters. middle-promoter activation requires the t4 transcriptional activator mota and coactivator asia, which are known to interact with σ(70), the specifi ... | 2010 | 20729353 |
| locally advanced thyroid cancer: can ct help in prediction of extrathyroidal invasion to adjacent structures? | the purpose of this study was to determine the diagnostic accuracy of ct for detecting extrathyroidal invasion of thyroid cancer to adjacent structures. | 2010 | 20729422 |
| redox regulation of myocardial erk 1/2 phosphorylation in experimental hyperthyroidism: role of thioredoxin-peroxiredoxin system. | the present study was conducted to test whether adaptation in the antioxidant system would differentially modulate prosurvival and proapoptotic proteins in hyperthyroidism-induced cardiac hypertrophy. male wistar rats were divided into 4 groups: control, vitamin e (20 mg · kg(-1) · d(-1) subcutaneously, 28 days), thyroxine (t4) (12 mg/l in drinking water for 28 days), and t4 + vitamin e. cardiac mass, redox ratio, glutathione peroxidase (gpx) and glutathione reductase (gr) activities, nf-e2-rela ... | 2010 | 20729758 |
| thyroid hormone can favorably remodel the diabetic myocardium after acute myocardial infarction. | it has been previously shown that regulators of physiological growth such as thyroid hormone (th) can favorably remodel the post ischaemic myocardium. here, we further explored whether this effect can be preserved in the presence of co-morbidities such as diabetes which accelerates cardiac remodeling and increases mortality after myocardial infarction. acute myocardial infarction (ami) was induced by left coronary ligation in rats with type i diabetes (dm) induced by streptozotocin administratio ... | 2010 | 20730619 |