Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| changes in monoterpene emission rates of quercus ilex infested by aphids tended by native or invasive lasius ant species. | the emission of volatile organic compounds (vocs) depends on temperature and light. other factors such as insect herbivory also may modify voc emission. in particular, aphid feeding promotes the release of new compounds and changes the composition of plant volatile blends. given that some aphids are tended by ants, we investigated whether ants change the emission of vocs indirectly through attendance on aphids. the effect of lachnus roboris aphids and two different tending ant species on terpene ... | 2010 | 20549328 |
| brominated diphenyl ether (bde) levels in liver, adipose, and milk from adult and juvenile rats exposed by gavage to the de-71 technical mixture. | brominated diphenyl ethers (bdes) are used as flame retardants in consumer products. rodent studies indicate that the liver, thyroid, and nervous system of developing animals are targets of bdes. to explore the relationship between exposure and health in developing animals, bde accumulation in adult and juvenile rats was examined in conjunction with changes in liver weight and serum thyroxine (t4). adult (f0) rats received the commercial bde mixture de-71 by gavage at doses of 0.5, 5, and 25 mg ... | 2010 | 20549633 |
| sentinel lymph node biopsy for papillary thyroid cancer: 12 years of experience at a single institution. | the purpose of this study was to report our experience with sentinel lymph node dissection (slnd) for papillary thyroid carcinoma, to evaluate the feasibility and safety of the procedure, and to examine its potential utility as a guide for central neck dissection. | 2010 | 20552407 |
| isolation and identification of acanthamoeba species related to amoebic encephalitis and nonpathogenic free-living amoeba species from the rice field. | isolation and characterization of the clinically relevant amphizoic amoebas in vegetated farmlands, which may present a risk to farmers' health. | 2010 | 20553339 |
| altered thyroid hormones and behavioural change in a sub-population of rats following chronic constriction injury. | hypothyroidism is associated with a disturbance of behaviour and mood. there are also individuals, not classified as hypothyroid, with low to 'low normal' thyroid hormone levels and normal thyroid-stimulating hormone (tsh) levels who have mood and behavioural changes. as the peripheral thyroid hormones decrease, tsh is expected to increase. however, there are a number of physiological mechanisms known to suppress tsh. in the present study, we report on thyroid hormone regulation in a rat model o ... | 2010 | 20553369 |
| treatment of cancer-related chest wall pain using spinal cord stimulation. | it has been estimated that 15% to 40% of chronic cancer pain has a neuropathic component, and this type of pain often responds poorly to opioids. in an attempt to provide increased pain relief for patients with intractable cancer pain, unconventional agents and interventional management approaches have received considerable attention. spinal cord stimulation (scs) has been used with increased frequency for the treatment of intractable cancer pain. | 2010 | 20555037 |
| platysma myocutaneous flap for oral cavity reconstruction. | a retrospective study was conducted to assess outcomes of reconstruction of the oral cavity with the platysma myocutaneous flap, in terms of flap survival, complications, and quality of life. included were 10 patients with squamous cell carcinoma (stage t1 to t4; nodal status n0 to n2) of the oral cavity who were treated between 2002 and 2006. each patient underwent tumor resection, modified radical neck dissection, and primary reconstruction with a platysma myocutaneous flap. operating time, le ... | 2010 | 20556740 |
| thyroid axis dysfunction in patients with prader-willi syndrome during the first 2 years of life. | prader-willi syndrome (pws) is a genetic disorder caused by the loss of expression of paternally transcribed genes in a highly imprinted region of chromosome 15q11-13. the clinical phenotype has been well characterized, mostly related to hypothalamic dysfunction. even though central hypothyroidism has been documented in 20-30% of patients with pws, thyroid function during the first 2 years of life has not been clearly defined. | 2010 | 20560980 |
| sacral neuromodulation in children with urinary and fecal incontinence: a multicenter, open label, randomized, crossover study. | the clinical benefit of sacral neuromodulation is unclear due to the paucity of randomized trial data. the purpose of this study was to evaluate sacral neuromodulation for management of urinary and fecal incontinence in a pediatric population. | 2010 | 20561645 |
| goitrogenic/antithyroidal potential of green tea extract in relation to catechin in rats. | catechins are flavonoids found in abundance in green tea, have elicited high interest due to their beneficial effects on health. though flavonoids have been reported to have an antithyroid effect and also to be goitrogenic there have been no reports about the effect of green tea on rat thyroid. the present study was designed to examine whether high doses of green tea has any harmful effect on thyroid physiology. for this purpose green tea extract was administered orally to male albino rats for 3 ... | 2010 | 20561943 |
| bacteriophage-based biosorbents coupled with bioluminescent atp assay for rapid concentration and detection of escherichia coli. | wild type t4 bacteriophage and recombinant t4 bacteriophages displaying biotin binding peptide (bccp) and cellulose binding module (cbm) on their heads were immobilized on nano-aluminum fiber-based filter (disruptor), streptavidin magnetic beads and microcrystalline cellulose, respectively. infectivity of the immobilized phages was investigated by monitoring the phage-mediated growth inhibition of bioluminescent e. coli b and cell lysis using bioluminescent atp assay. the results showed that pha ... | 2010 | 20561957 |
| polybrominated diphenyl ether (pbde) flame retardants and thyroid hormone during pregnancy. | human exposure to polybrominated diphenyl ether (pbde) flame retardants has increased exponentially over the last three decades. animal and human studies suggest that pbdes may disrupt thyroid function. although thyroid hormone (th) of maternal origin plays an essential role in normal fetal brain development, there is a paucity of human data regarding associations between exposure to pbdes and maternal th levels during pregnancy. | 2010 | 20562054 |
| laparoscopic colorectal surgery produces better outcomes for high risk cancer patients compared to open surgery. | the excellent outcomes reported for laparoscopic colorectal surgery in selected patients could also be potentially advantageous for high risk patients. this prospective study was designed to examine the feasibility and safety of laparoscopic resection in high risk patients with colorectal cancer. | 2010 | 20562603 |
| the bispectral electroencephalogram during modified electroconvulsive therapy under propofol anesthesia: relation with seizure duration and awakening. | implication statement:: use of the bispectral electroencephalogram during modified electroconvulsive therapy (mect) under propofol anesthesia was found to be an accurate predictor of seizure duration and awakening. this may have potential clinical implications on therapeutic success and elimination of the undesirable effects associated with this treatment modality. | 2010 | 20562643 |
| sewage bacteriophage inactivation by cationic porphyrins: influence of light parameters. | photodynamic therapy has been used to inactivate microorganisms through the use of targeted photosensitizers. although the photoinactivation of microorganisms has already been studied under different conditions, a systematic evaluation of irradiation characteristics is still limited. the goal of this study was to test how the light dose, fluence rate and irradiation source affect the viral photoinactivation of a t4-like sewage bacteriophage. the experiments were carried out using white par light ... | 2010 | 20563346 |
| identification of qtl associated with resistance to bacterial spot race t4 in tomato. | bacterial spot of tomato (solanum lycopersicum l.), caused by several xanthomonas sp., is a serious but difficult disease to control by chemical means. development of resistance has been hindered by emergence of races virulent to tomato, by the quantitative inheritance of resistance, and by a low correlation between seedling assays and resistance in the field. resistance to multiple races, including race t4, has been described in the s. lycopersicum var. cerasiformae accession pi 114490. we used ... | 2010 | 20563547 |
| molecular cloning and regulation of mrna expression of the thyrotropin β and glycoprotein hormone α subunits in red drum, sciaenops ocellatus. | full-length cdnas for thyrotropin β (tshβ) and glycoprotein hormone α (gsuα) subunits were cloned and sequenced from the red drum (sciaenops ocellatus). the cdnas for tshβ (877 bp) and gsuα (661 bp) yielded predicted coding regions of 126 and 94 amino acid proteins, respectively. both sequences contain all invariant cysteine and putative glycosylated asparagines characteristic of each as deduced by comparison with other gsuα and tshβ sequences from representative vertebrate species. multiple pro ... | 2010 | 20563882 |
| multifactorial, site-specific recurrence model after radical cystectomy for urothelial carcinoma. | a scoring algorithm of site-specific disease recurrence after cystectomy for urothelial carcinoma was designed. | 2010 | 20564121 |
| 2,3,7,8,12,13-hexaaryltruxenes: an ortho-substituted multiarm design and microwave-accelerated synthesis toward starburst macromolecular materials with well-defined pi delocalization. | we present herein a novel design and the efficient synthesis towards a "homogeneous" starburst fluorene system based on the novel 2,3,7,8,12,13-hexaaryltruxene scaffold. controlled microwave heating provides a facile and powerful approach for each step in the synthesis of these bulky materials with large steric hindrance, suggesting an avenue to access structurally well-defined complex organic semiconductors (oscs) rapidly and conveniently with high yield and purity. the resulting materials exhi ... | 2010 | 20564289 |
| accuracy of multidetector computed tomography in identifying poor prognostic factors in colonic cancer. | recent neoadjuvant strategies for high-risk colonic tumours have renewed interest in accurate preoperative staging. the aim of this study was to validate prospectively the accuracy of multidetector computed tomography (mdct) in stratifying patients into good and poor prognostic groups in a multicentre setting. | 2010 | 20564305 |
| factors associated with nonparticipation in one-year quality-of-life assessment in patients with head and neck squamous cell carcinoma. | to identify factors associated with nonparticipation in long-term quality-of-life (qol) analysis in head and neck squamous cell cancer (hnscc) patients. | 2010 | 20564472 |
| sequential chemoradiotherapy in advanced laryngeal cancer: an institutional experience. | the objective of this study was to determine the efficacy of sequential chemoradiation for larynx preservation. | 2010 | 20565422 |
| genetically engineered virulent phage banks in the detection and control of emergent pathogenic bacteria. | natural outbreaks of multidrug-resistant microorganisms can cause widespread devastation, and several can be used or engineered as agents of bioterrorism. from a biosecurity standpoint, the capacity to detect and then efficiently control, within hours, the spread and the potential pathological effects of an emergent outbreak, for which there may be no effective antibiotics or vaccines, become key challenges that must be met. we turned to phage engineering as a potentially highly flexible and eff ... | 2010 | 20569057 |
| overlap extension pcr cloning: a simple and reliable way to create recombinant plasmids. | here we describe a straightforward, efficient, and reliable way to clone an insert of choice into a plasmid of choice without restriction endonucleases or t4 dna ligase. chimeric primers containing plasmid sequence at the 5' ends and insert sequence at the 3' ends were used to pcr-amplify insertion sequences of various sizes, namely the genes for gfp (gfp), beta-d-glucuronidase (gusa), and beta-galactosidase (lacz), as well as the entire luxabcde operon. these inserts were employed as mega-prime ... | 2010 | 20569222 |
| thyroid function in children with growth hormone (gh) deficiency during the initial phase of gh replacement therapy - clinical implications. | abstract: | 2010 | 20307267 |
| cyclobutane pyrimidine dimers are photosensitised by carprofen plus uva in human hacat cells. | every year in the uk about 75,000 cases of non-melanoma skin cancer (nmsc) are registered, and about 9500 people are diagnosed with cutaneous melanoma (cm). the main risk factor for these cancers is exposure to sunlight. the effects of light on skin are wavelength dependent, with wavelengths in the uvb waveband (280-315 nm) being the most carcinogenic. uvb is directly absorbed by dna, producing dimeric pyrimidine photoproducts including cyclobutane pyrimidine dimers (cpd) and pyrimidine (6-4) py ... | 2010 | 20307647 |
| sodium nitroprusside infusion prevents hypothyroidism in patients undergoing coronary artery bypass grafting: a prospective randomized clinical trial. | the level of thyroid hormones is an important factor in determining the outcome of coronary artery bypass patients. sodium nitroprusside (snp) is a natural donor of nitric oxide which has been shown to interfere with thyroid hormone synthesis. whether clinical use of sodium nitroprusside has any effect on thyroid function has not yet been investigated. the aim of this study was to investigate the effects of snp administration on circulating levels of thyroid hormones. | 2010 | 20308916 |
| characteristic effect of an anticancer dinuclear platinum(ii) complex on the higher-order structure of dna. | it is known that a 1,2,3-triazolato-bridged dinuclear platinum(ii) complex, [{cis-pt(nh(3))(2)}(2)(micro-oh)(micro-1,2,3-ta-n (1),n (2))](no(3))(2) (amta), shows high in vitro cytotoxicity against several human tumor cell lines and circumvents cross-resistance to cisplatin. in the present study, we examined a dose- and time-dependent effect of amta on the higher-order structure of a large dna, t4 phage dna (166 kbp), by adapting single-molecule observation with fluorescence microscopy. it was fo ... | 2010 | 20237813 |
| a sensitive ligase-based atp electrochemical assay using molecular beacon-like dna. | a sensitive and selective ligase-based signal-on electrochemical sensing method for adenosine-5'-triphosphate (atp) detection had been developed using molecular beacon (mb)-like dna. in this method, the biotin-tagged mb-like dna was self-assembled onto a gold electrode to form a stem-loop structure by means of facile gold-thiol chemistry, which resulted in blockage of electronic transmission. it was et off state. in the presence of atp, two nucleotide fragments which were complementary to the lo ... | 2010 | 20299199 |
| nanofluidics in hollow nanowires. | we present a novel scheme for producing nanotube membranes using free-standing hollow nanowires, with easily controllable dimensions. gaas-alinp core-shell nanowires were grown by metal-organic vapor phase epitaxy and were partially embedded in a polymer film. the gaas core and substrate were etched selectively, leaving tubes with open access to both sides of the membrane. electrophoretic transport of t4-phage dna through the hollow nanowires was demonstrated using epifluorescence microscopy. | 2010 | 20299730 |
| effect of intraoperative acetated ringer's solution with 1% glucose on glucose and protein metabolism. | to investigate the effects of the intraoperative administration of ringer's solution with 1% glucose on the metabolism of glucose, lipid and muscle protein during surgery. | 2010 | 20300778 |
| [mobitz type ii block during one-lung ventilation]. | we present a case of mobitz type ii atrioventricular block during one-lung ventilation in a 74-year-old man with lung cancer under anesthesia. premedication with atropine 0.5 mg and midazolam 2 mg intramuscularly were given 30 min before entering the operating room. before anesthesia, his heart rate was 72 beats x min(-1) with normal sinus rhythm and blood pressure was 120/70 mmhg. an epidural catheter was placed at t4-5 interspace and 1.5% mepivacaine was infused (7 ml bolus and 5 ml x hr(-1) t ... | 2010 | 20229756 |
| external beam radiotherapy with endocavitary boost for nasopharyngeal cancer: treatment results and late toxicity after extended follow-up. | to evaluate the long-term outcome after treatment of nasopharyngeal carcinoma and assess late toxicity in a multidisciplinary clinic. | 2010 | 20231060 |
| gene network visualization and quantitative synteny analysis of more than 300 marine t4-like phage scaffolds from the gos metagenome. | bacteriophages (phages) are the most abundant biological entities in the biosphere and are the dominant "organisms" in marine environments, exerting an enormous influence on marine microbial populations. metagenomic projects, such as the global ocean sampling expedition (gos), have demonstrated the predominance of tailed phages (caudovirales), particularly t4 superfamily cyanophages (cyano-t4s), in the marine milieu. whereas previous metagenomic analyses were limited to gene content information, ... | 2010 | 20231334 |
| presence of tumor-infiltrating lymphocytes and a dominant nodule within primary melanoma are prognostic factors for relapse-free survival of patients with thick (t4) primary melanoma: pathologic analysis of the e1690 and e1694 intergroup trials. | lymphocytic infiltration of primary cutaneous melanoma has been demonstrated to be of prognostic significance. tumor infiltrating lymphocytes (tils) were evaluated on histologic sections of pt4 primary cutaneous melanoma from 293 patients, accrued in protocols 1690 and 1694 of the eastern cooperative oncology group. data for the 60-month follow-up were available. statistical analysis of the pathologic data evaluated the correlation of regional lymph node metastasis and response to interferon the ... | 2010 | 20231618 |
| narrowband imaging for early detection of malignant tumors and radiation effect after treatment of head and neck cancer. | to determine the value of narrowband imaging (nbi) screening for the early detection of head and neck squamous cell carcinoma (hnscc) in patients who have received treatment and to assess the impact of radiotherapy on detection rates. | 2010 | 20231639 |
| thyroid hormones induce activation of rat hepatic stellate cells through increased expression of p75 neurotrophin receptor and direct activation of rho. | we have previously shown that hyperthyroidism is detrimental for liver fibrosis and in this study we have investigated the mechanisms regulating triiodothyronine (t3) and l-thyroxine (t4) activation of hepatic stellate cells (hsc). expression of alpha-smooth muscle actin (alphasma) and p75 neurotrophin receptor (p75ntr) was determined by western blot analyses and transient transfection of the promoters. rho activation was assayed using a pull-down assay and by elisa. expression of thyroid hormon ... | 2010 | 20231820 |
| a quick and reliable eeg montage for the detection of seizures in the critical care setting. | obtaining an emergent eeg for the diagnosis of nonconvulsive status epilepticus and conconvulsive seizures in the intensive care unit raises logistic problems in most hospitals. previous studies have looked into the hairline eeg for a broader population than the critically ill, with controversial conclusions. the authors created a montage sufficiently simple to be performed and interpreted by residents and rapidly achievable to meet the time constraints of a busy on-call schedule. seven electrod ... | 2010 | 20234318 |
| [steroid replacement therapy for shocks after cardiac surgery]. | a 63-year-old woman who underwent surgery for valve replacement had shocks 2 times. first, 1 postoperative day (pod), she had dyspnea, high grade fever and tacycardia. then, she was intubated again, and needed intraaortic ballon pumping (iabp) support. second, 32 pod, she had dyspnea, loss of consciousness and metabolic acidosis. then she was intubated and needed continuous hemodiafiltration (chdf). in both cases, causes were unknown, but she recovered from shocks after steroid therapy. relative ... | 2010 | 20214348 |
| t4n0m0 nasopharyngeal carcinoma patients: do they have a distinct tumor biology? | to investigate the clinical manifestations and treatment outcomes of non-metastatic t4n0 nasopharyngeal cancer patients, and to compare them with other stage iva subgroups of patients. | 2010 | 20214552 |
| impact of computer-based patient education on illness-specific knowledge and renal function in adolescents after renal transplantation. | interactive cbe holds potential to increase irk and irb in adolescents following transplantation. an experimental design assessed the effect of cbe on irk and renal function in adolescents after transplantation (n = 50, aged 15-20 yr). the igr (n = 26) completed a nine-item questionnaire (9-iq) covering irk and irb prior to completing cbe at three consecutive time points (t0-t2). the cgr (n = 24) received standard care. renal function was determined by gfr 12 months before, at start of intervent ... | 2010 | 20214742 |
| impact of tumor response on survival after radiochemotherapy in locally advanced rectal carcinoma. | in locally advanced rectal adenocarcinoma, preoperative radiochemotherapy induces tumor response. the impact of pathologic tumor response on survival is still debated because of the numerous distinct tumor-response gradings available in the literature and the lack of standardized pathologic approach. the objective of this work was to study the impact of tumor response on survival, according to the 4 main tumor-response gradings available in the literature in locally advanced rectal adenocarcinom ... | 2010 | 20216380 |
| the terminal 5' phosphate and proximate phosphorothioate promote ligation-independent cloning. | function studies of many proteins are waited to develop after genome sequencing. high-throughout technology of gene cloning will strongly promote proteins' function studies. here we describe a ligation-independent cloning (lic) method, which is based on the amplification of target gene and linear vector by pcr using phosphorothioate-modified primers and the digestion of pcr products by lambda exonuclease. the phosphorothioate inhibits the digestion and results in the generation of 3' overhangs, ... | 2010 | 20217896 |
| distinctive clinical and microscopic features of squamous cell carcinoma of oral cavity and lip. | this study was undertaken to gain insight into the distinctive features of squamous cell carcinoma of the lip (lscc) and oral cavity (ocscc). | 2010 | 20219590 |
| a longitudinal comparison of arm morbidity in stage i-ii breast cancer patients treated with sentinel lymph node biopsy, sentinel lymph node biopsy followed by completion lymph node dissection, or axillary lymph node dissection. | long-term shoulder and arm function following sentinel lymph node biopsy (slnb) may surpass that following complete axillary lymph node dissection (clnd) or axillary lymph node dissection (alnd). we objectively examined the morbidity and compared outcomes after slnb, slnb + clnd, and alnd in stage i/ii breast cancer patients. | 2010 | 20221902 |
| p22 coat protein structures reveal a novel mechanism for capsid maturation: stability without auxiliary proteins or chemical crosslinks. | viral capsid assembly and stability in tailed, dsdna phage and herpesviridae are achieved by various means including chemical crosslinks (unique to hk97), or auxiliary proteins (lambda, t4, phi29, and herpesviruses). all these viruses have coat proteins (cp) with a conserved, hk97-like core structure. we used a combination of trypsin digestion, gold labeling, cryo-electron microscopy, 3d image reconstruction, and comparative modeling to derive two independent, pseudoatomic models of bacteriophag ... | 2010 | 20223221 |
| pituitary-adrenal functions in a hereditary hypothyroid (rdw) rat. | the rdw rat is a hereditary hypothyroid strain isolated from wistar-imamichi rats. in the present study, adrenocorticotropic hormone (acth) and corticosterone responses to restraint stress (120 min) were examined in rdw adult male rats. acth response to restraint stress was higher in rdw rats than in hetero control rats. the plasma concentrations of corticosterone were lower in rdw rats than in control rats during the first 30 min after the onset of stress. both acth and corticosterone responses ... | 2010 | 20224173 |
| acute thyroiditis complicating parathyroidectomy. | this report describes a 59-year-old man who presented 10 days after surgery for hyperparathyroidism with pulmonary edema, mildly abnormal echocardiogram, and elevated free t4 level with suppressed thyroid-stimulating hormone level. follow-up documented resolution of the elevated free t4 level with 24-hour thyroid scan and uptake at 60 days showing reduced uptake and normal gland anatomy. previous case reports have been made of thyroiditis at variable time intervals after parathyroidectomy and ar ... | 2010 | 20224309 |
| late-life depressed mood and weight change contribute to the risk of each other. | weight change may be considered an effect of depression. in turn, depression may follow weight change. deteriorations in health may mediate these associations. the objective was to examine reciprocal associations between depressed mood and weight change, and the potentially mediating role of deteriorations in health (interim hospitalizations and incident mobility imitation) in these associations. | 2010 | 20224519 |
| phase ii study of preoperative chemoradiotherapy (crt) with irinotecan plus s-1 in locally advanced rectal cancer. | the aim of this study is to evaluate the efficacy and safety of preoperative radiation therapy combined with s-1 and irinotecan (si) in larc. | 2010 | 20211505 |
| comfortable lifestyle-induced imbalance of neuro-endocrine-immunity network: a possible mechanism of vascular endothelial dysfunction. | to observe the changes of vascular endothelial functions and general neuro-endocrine-immunity (nei) network under the state of qi-deficiency syndrome induced by excessive idleness and to approach their internal relevance and illuminate initially the pathophysiological mechanism of vascular lesion induced by excessive idleness. | 2010 | 20131037 |
| [free anterolateral thigh myocutaneous flap for reconstruction of soft tissue defects following en block resection of tongue cancer]. | to evaluate the results of the reconstruction of the soft tissue defects following the en block resection of tongue cancer using free anterolateral thigh myocutaneous flaps. | 2010 | 20135979 |
| [improvement of lasting effects in outpatient pulmonary rehabilitation with special regard to exercise therapy and sports]. | the aim of this study was to evaluate the effects of outpatient medical rehabilitation (omr) mainly composed of exercise therapy and sports for patients with asbestosis. following the hamburg model, the omr focuses on keeping up lasting effects. | 2010 | 20178059 |
| prognostic value of preoperative clinical staging assessed by computed tomography in resectable gastric cancer patients: a viewpoint in the era of preoperative treatment. | in the era of pre- or perioperative therapy for gastric cancer, clinical staging before treatment appears to be increasingly important for prognosis, yet there are no data on the subject for resectable gastric cancer patients. | 2010 | 20179530 |
| examination of the efficacy of acute l-alanyl-l-glutamine ingestion during hydration stress in endurance exercise. | abstract: | 2010 | 20181080 |
| acute myocardial infarction as the first presentation of thyrotoxicosis in a 31-year old woman - case report. | abstract: : a 31-year old woman, previously fit & well was admitted with pressing retrosternal chest pain and palpitations of sudden onset. her body weight was normal (bmi 20.5 kg/m2) and there was no significant family history of cardiac disease. she smoked, however, about 15 cigarettes a day and she had been taking combined oral contraceptive pill (cilest(r)) for about three years. on admission she appeared sweaty and in pain, blood pressure 130/70 mmhg, heart rate about 110/min, mild lid-lag ... | 2010 | 20181115 |
| treatment results of radiation therapy for muscle-invasive bladder cancer. | to assess local control and survival rates in patients with muscle-invasive bladder cancer treated with external-beam radiotherapy and to investigate prognostic factors. | 2010 | 20354664 |
| the effect of dietary laminaria-derived laminarin and fucoidan on nutrient digestibility, nitrogen utilisation, intestinal microflora and volatile fatty acid concentration in pigs. | in experiment 1, 30 boars were assigned to one of five treatments (n = 6): t1, 0 g kg(-1) seaweed extract (swe); t2, 0.7 g kg(-1) swe; t3, 1.4 g kg(-1) swe; t4, 2.8 g kg(-1) swe and t5, 5.6 g kg(-1) swe. the extract contained laminarin and fucoidan only and was extracted from laminaria spp. in experiment 2, 28 boars were assigned, in a 2 x 2 factorial to one of four treatments (n = 7): t1, control; t2, control plus 300 mg laminarin; t3, control plus 240 mg fucoidan; t4, control plus 300 mg lamin ... | 2010 | 20355064 |
| electrochemical biosensor microarray functionalized by means of biomolecule friendly photolithography. | microfabrication permits the incorporation of dense electrode arrays in microsystems and small volume diagnostic devices. however, the specific functionalization of arbitrary shape electrodes with different biomolecules remains a challenging issue. in the present work, the problem of fabricating closely spaced microelectrodes (20 microm sensor diameter and 20 microm-spaced interdigitated electrodes array) that can be modified selectively in order to create multi-analyte sensor arrays is addresse ... | 2010 | 20356728 |
| histone variant macroh2a1 deletion in mice causes female-specific steatosis. | vertebrate heterochromatin contains a non-allelic variant of the histone h2a called macroh2a1, which has the characteristic of being three times the size of the canonical h2a. the macroh2a1 c-terminal extension can recruit onto chromatin the poly-adp-ribose polymerase (parp)1, which is crucial for dna repair. this led to the speculation that macroh2a1 could be essential for genome surveillance; however, no experimental evidence supported this hypothesis. because macroh2a1 has been found to be en ... | 2010 | 20359320 |
| alternative splicing variant of kallikrein-related peptidase 8 as an independent predictor of unfavorable prognosis in lung cancer. | a relatively unexplored area for biomarker identification is alternative splice variants. we undertook this study to evaluate the usefulness of mrna isoforms encoded by the klk8 (kallikrein-related peptidase 8) gene as prognostic markers for lung cancer. | 2010 | 20360129 |
| improving prediction of lateral node spread in low rectal cancers--multivariate analysis of clinicopathological factors in 1,046 cases. | this study aims to search for independent predictors of lateral node metastasis in low rectal cancers. | 2010 | 20361335 |
| low-temperature t4-like coliphages vb_ecom-vr5, vb_ecom-vr7 and vb_ecom-vr20. | bacteriophages vb_ecom-vr5, vb_ecom-vr7 and vb_ecom-vr20, showing an unusual low-temperature plating profile and producing constantly growing plaques, were isolated from aquatic environments of lithuania. although vb_ecom-vr5, vb_ecom-vr7 and vb_ecom-vr20 resembled phage t4 both in their genome size and in their major structural protein (gp23) pattern, physiological properties of all three phages tested differed significantly from those of t4. with an optimum temperature for plating around 24 de ... | 2010 | 20361343 |
| multifrequency electron spin resonance study of the dynamics of spin labeled t4 lysozyme. | an extensive set of electron spin resonance spectra was obtained over a wide range of frequencies (9, 95, 170, and 240 ghz) and temperatures (2 to 32 degrees c) to explore the dynamic modes of nitroxide-labeled t4 lysozyme in solution. a commonly used nitroxide side chain (r1), or a methylated analogue with hindered internal motion (r2), was substituted for the native side chain at solvent-exposed helical sites, 72 or 131. the spectra at all four frequencies were simultaneously fit with the slow ... | 2010 | 20361789 |
| is pulmonary function damaged by neoadjuvant lung cancer therapy? a comprehensive serial time-trend analysis of pulmonary function after induction radiochemotherapy plus surgery. | we have analyzed short- and long-term variations of pulmonary function in locally advanced non-small cell lung cancer after induction chemoradiotherapy. | 2010 | 20363001 |
| effect of serum estradiol and leptin levels on thyroid function, food intake and body weight gain in female wistar rats. | we evaluated the interplay among estrogen, leptin and thyroid function in the regulation of body mass in female rats. adult female rats were divided into four groups: control (c, sham-operated), ovariectomized (ovx), ovariectomized treated with estradiol benzoate (eb) 0.7 or 14microg/100gbw per day, during 21 days. ovx led to an increase in body mass, food intake and food efficiency (change in body mass as function of the amount of food ingested) which were normalized by the lower eb dose, and d ... | 2010 | 20363238 |
| iterative surgical resection of a recurrent gallbladder carcinoma with long-term survival: report of a case. | gallbladder carcinoma is a rare, but often lethal disease. unfortunately, at the time of diagnosis, patients usually have advanced disease (t3-t4) and long-term survival is dismal, ranging from 5 to 12% in the literature. however, this cancer can be successfully treated when the tumour is organ-confined (t1-t2 tumours), as happens in the case of incidental diagnosis at the time of cholecystectomy for gallstones. here we describe a patient with recurrent gallbladder carcinoma who, treated with it ... | 2010 | 20363997 |
| [factors contributing to gallstone formation and their interaction]. | to study factors contributing to gallstone formation and to elucidate their relationship. | 2010 | 20364691 |
| optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts. | hypothyroidism and thyrotoxicosis are each associated with an increased risk of fracture. although thyroxine (t4) is the predominant circulating thyroid hormone, target cell responses are determined by local intracellular availability of the active hormone 3,5,3'-l-triiodothyronine (t3), which is generated from t4 by the type 2 deiodinase enzyme (d2). to investigate the role of locally produced t3 in bone, we characterized mice deficient in d2 (d2ko) in which the serum t3 level is normal. bones ... | 2010 | 20368437 |
| prognostic accuracy of computed tomography findings for patients with laryngeal cancer undergoing laryngectomy. | the indications for upfront laryngectomy in the management of laryngeal cancer are a functionless larynx and extralaryngeal extension. practically, clinicians rely on imaging to predict which patients will have t4 disease. our goal was to review the accuracy of preoperative computed tomography (ct) scanning in determining the necessity for initial laryngectomy for advanced laryngeal cancer. | 2010 | 20368569 |
| [effectiveness of between--hospital cooperation in staging laparoscopy]. | it is difficult to perform the staging of laparoscopy within the restricted time at a high-volume center. we thus started between-hospital cooperation as of april 2008. in this hospital cooperation, we perform surgery after laparoscopic examination at a cooperating hospital. | 2010 | 20332687 |
| [a case of stage iv afp producing gastric cancer with long-term survival treated by adjuvant chemotherapy with s-1]. | a 66-year-old woman underwent a total gastrectomy for advanced gastric cancer of cardia. the histological diagnosis was moderately-differentiated tubular adenocarcinoma and the pathological stage was iv: t4 (diaphragm), n2, m0. microscopically, there were findings of severe lymphatic and venous invasions with intravenous tumor thrombus around the splenic hilum. immunohistochemical staining confirmed afp production of the tumor. the risk of recurrence was considered very high and her prognosis ve ... | 2010 | 20332696 |
| mobile regulatory cassettes mediate modular shuffling in t4-type phage genomes. | coliphage phi1, which was isolated for phage therapy in the republic of georgia, is closely related to the t-like myovirus rb49. the approximately 275 open reading frames encoded by each phage have an average level of amino acid identity of 95.8%. rb49 lacks 7 phi1 genes while 10 phi1 genes are missing from rb49. most of these unique genes encode functions without known homologs. many of the insertion, deletion, and replacement events that distinguish the two phages are in the hyperplastic regio ... | 2010 | 20333230 |
| prognostic heterogeneity in multilevel n2 non-small cell lung cancer patients: importance of lymphadenopathy and occult intrapulmonary metastases. | to evaluate prognostic heterogeneity that may exist in multilevel n2 non-small lung cancer, we attempted to identify clinicopathologic prognostic factors for multilevel n2 patients who underwent standard surgeries. | 2010 | 20338307 |
| preoperative capecitabine and pelvic radiation in locally advanced rectal cancer--is it equivalent to 5-fu infusion plus leucovorin and radiotherapy? | the aim of this retrospective case-matching study was to compare the treatment outcomes and acute toxicity of preoperative radiotherapy (rt) with capecitabine vs. preoperative rt with intermittent 5-fluorouracil (5-fu) infusion, leucovorin, and mitomycin c in rectal cancer. | 2010 | 20338475 |
| relationship of thyroid function with body mass index and insulin-resistance in euthyroid obese subjects. | it is recognized that overt thyroid dysfunction is associated with weight changes, but the influence of a minor alteration of thyroid function remains unclear. this study aimed to further investigate the relationship between obesity and thyroid function and to examine the possible role of insulin resistance on the hypothalamic-pituitary- thyroid axis. | 2010 | 20339314 |
| isolation, morphologic, serologic and molecular identification of acanthamoeba t4 genotype from the liver of a temminck's tragopan (tragopan temminckii). | members of the genus acanthamoeba are usually free-living amoebae that are found in a variety of ecological niches including soil, fresh and brackish water, dust in the air, heating, ventilating, and air conditioning filters, swimming pools and hot tubs. occasionally they are also known to cause central nervous system infections in humans and animals. we isolated into culture an amoeba from the liver of a temminck's tragopan (horned pheasant) (tragopan temminckii) that died of amoebic infection. ... | 2010 | 20347228 |
| double l-shaped free-style perforator flap for perineal and vaginal reconstruction after cylindrical abdominoperineal resection. | the improvement of patient carcinological status by an abdominoperineal resection by extended posterior perineal approach in a prone position requires the plastic surgeon to consider other reconstructive options. we present an original double l-shaped free-style propeller flap used to reconstruct the vagina and the perineum of a 57-year-old patient after the resection of a t4 tumour of the lower rectum. | 2010 | 20347625 |
| laparoscopic rectal surgery: does immediate outcome differ in respect to sex? | this study analyzed the immediate postoperative outcome of the laparoscopic approach to the rectum in relation to the sex of the patient. | 2010 | 20305444 |
| accuracy of endoscopic ultrasound in preoperative staging of esophageal cancer: results from a referral center for early esophageal cancer. | endoscopic ultrasound (eus) has been regarded as the most accurate staging tool in esophageal cancer. staging results have a strong impact on the decision as to whether a patient should undergo endoscopic treatment, surgery alone, or neoadjuvant therapy. this retrospective study was conducted to analyze the accuracy of esophageal cancer staging using eus. | 2010 | 20306385 |
| diffusion-weighed mr of the thyroid gland in graves' disease: assessment of disease activity and prediction of outcome. | to assess the activity and clinical course of graves' disease with diffusion-weighted magnetic resonance (mr) imaging. | 2010 | 20350826 |
| inhibitory effect of thyroid blocking antibody (tbab) on the thyroid stimulatory effect of human chorionic gonadotropin (hcg) and equine chorionic gonadotropin (ecg). | we examined the inhibitory effect of thyroid blocking antibody (tbab) on the thyroid stimulating activity of human chorionic gonadotropin (hcg) and equine cg (ecg). five tbab positive sera obtained from patients who had been hypothyroid but were currently on t4 treatment. the tsh binding inhibitory immunoglobulin (tbii) activities of the sera were 60-160 iu/l. inhibition of tsh binding to the tsh receptor (tshr) [tsh binding inhibition (tbi) activity] of hcg or ecg, and inhibition of tbab on hcg ... | 2010 | 20351465 |
| coping with the unexpected at surgery. | in lung cancer surgery, it is best to avoid surprises; this requires knowledge of the reliability of preoperative assessment and careful planning. if this has been done, most of the more common situations should be manageable. if there is limited chest wall, mediastinal or n2 node involvement, one should proceed with resection. unanticipated t4 tumors or bulky pn2 disease should not come as a surprise, and such patients should be sent to a more experienced center. one has to be careful to practi ... | 2010 | 20387297 |
| [clinical studies on renal cell carcinoma]. | we reviewed 193 patients of renal cell carcinoma treated at osaka police hospital between 1990 and 2006. | 2010 | 20387516 |
| the center for alternatives to animal testing - europe (caat-eu): a transatlantic bridge for the paradigm shift in toxicology. | the center for alternatives to animal testing - europe (caat-eu) was founded based collaboration between the johns hopkins bloomberg school of public health and the university of konstanz. caat-eu, housed at the university of konstanz, will coordinate transatlantic activities to promote humane science in research and education, and participate, as partner or coordinator, in publicly and privately funded european projects. thomas hartung will serve as program liaison representing johns hopkins un ... | 2010 | 20390240 |
| isolation and characterization of differentially expressed transcripts from the suspension cells of oil palm (elaeis guineensis jacq.) in response to different concentration of auxins. | oil palm suspension cultures were initiated by transferring the gel-like friable embryogenic tissue onto liquid medium supplemented with auxins. in this study, transcripts that were differentially expressed in oil palm suspension cells cultured at different auxin concentrations were examined using suppression subtractive hybridization. total rna was first isolated from oil palm suspension cells proliferated in liquid medium with different hormone concentrations for 6 months. four different hormo ... | 2010 | 20390382 |
| bunching effect in single-molecule t4 lysozyme nonequilibrium conformational dynamics under enzymatic reactions. | the bunching effect, implying that conformational motion times tend to bunch in a finite and narrow time window, is observed and identified to be associated with substrate-enzyme complex formation in t4 lysozyme conformational dynamics under enzymatic reactions. using single-molecule fluorescence spectroscopy, we have probed t4 lysozyme conformational motions under the hydrolysis reaction of polysaccharide of e. coli b cell walls by monitoring the fluorescence resonant energy transfer (fret) bet ... | 2010 | 20369804 |
| dna-binding properties of t4 uvsy recombination mediator protein: polynucleotide wrapping promotes high-affinity binding to single-stranded dna. | to carry out homologous recombination events in the cell, recombination proteins must be able to recognize and form presynaptic filaments on single-stranded dna (ssdna) in the presence of a vast excess of double-stranded dna (dsdna). therefore recombination machineries stringently discriminate between ssdna and dsdna lattices. recent single-molecule studies of bacteriophage t4 recombination proteins revealed that, surprisingly, the uvsy recombination mediator protein binds stronger to stretched ... | 2010 | 20371513 |
| structural, electrochemical, phosphate-hydrolysis, dna binding and cleavage studies of new macrocyclic binuclear nickel(ii) complexes. | new macrocyclic binuclear nickel(ii) complexes have been synthesized by using the bicompartmental mononuclear complex [nil] [3,30-((1e,7e)-3,6-dioxa-2,7-diazaocta-1,7-diene-1,8-diyl)bis(3-formyl-5-methyl-2-diolato)nickel(ii)] with various diamines like 1,2-bis(aminooxy)ethane (l(1)), 1,2-diamino ethane (l(2)), 1,3-diamino propane (l(3)), 1,4-diamino butane (l(4)), 1,2-diamino benzene (l(5)), and 1,8-diamino naphthalene (l(6)). the complexes were characterized by elemental analysis and spectrosco ... | 2010 | 20372706 |
| pre- and post-therapy nodal status equally affects survival of patients with oesophageal squamous cell carcinoma receiving preoperative chemoradiation. | patients with deeply invading (t3-t4) oesophageal cancers usually receive chemoradiotherapy with or without surgery. however, the prognostic significance of pre-therapy and post-therapy lymph node (ln) status remains unclear. we studied 195 patients who received chemoradiotherapy for deeply invading oesophageal cancers (t3-4, n0-1, m0). of these, 105 patients underwent surgery while 90 were treated by chemoradiotherapy alone. of the 105 surgically treated patients, overall survival was significa ... | 2010 | 20372848 |
| prognostic value of lymph node micrometastasis in patients with colorectal cancer in dukes stages a and b (t1-t4, n0, m0). | 30% of patients with colorectal cancer (crc) in dukes stages a and b (t1-t4, n0, m0) present tumor recurrence and die after 5 years follow up. this unexpectedly poor evolution might be attributable to the presence of lymph node micrometastasis undetected in routine examination with haematoxilin-eosine (h&e). | 2010 | 20373832 |
| efficacy of a spray compound containing a pool of collagen precursor synthetic aminoacids (l-proline, l-leucine, l-lysine and glycine) combined with sodium hyaluronate to manage chemo/radiotherapy-induced oral mucositis: preliminary data of an open trial. | oral mucositis (om) is a very frequent and potentially severe complication experienced by patients receiving chemotherapy and/or radiotherapy, which often leads to significant morbidity and mortality, and decreased quality of life, and is very costly. despite its severity and prevalence, there is no standard recognised management today. the aim of this open clinical trial is to evaluate the efficacy and compliance of a new spray compound containing sodium hyaluronate (sh) and a pool of collagen ... | 2010 | 20378002 |
| altered thyroxine metabolism in rainbow trout (oncorhynchus mykiss) exposed to hexabromocyclododecane (hbcd). | hexabromocyclododecane (hbcd) is an additive flame retardant used in consumer and industrial applications. our earlier work suggested that fish exposed to hbcd exhibited an increase in the rate of turnover of thyroxine (t4), the precursor molecule to the active thyroid hormone triiodothyronine (t3). to examine this further, juvenile rainbow trout were held in the laboratory and fed diets containing environmentally relevant concentrations of the individual alpha, beta or gamma isomers. thirty-two ... | 2010 | 20378152 |
| baseline serum testosterone in men treated with androgen deprivation therapy and radiotherapy for localized prostate cancer. | it is believed that men diagnosed with prostate cancer and a low baseline serum testosterone (bst) may have more aggressive disease, and it is frequently recommended they forego testosterone replacement therapy. we used two large phase iii trials involving androgen deprivation therapy and external beam radiation therapy to assess the significance of a bst. | 2010 | 20378270 |
| decompressive surgery in a patient with posttraumatic syringomyelia. | posttraumatic syringomyelia may result from a variety of inherent conditions and traumatic events, or from some combination of these. many hypotheses have arisen to explain this complex disorder, but no consensus has emerged. a 28-year-old man presented with progressive lower extremity weakness, spasticity, and decreased sensation below the t4 dermatome five years after an initial trauma. magnetic resonance imaging (mri) revealed a large, multi-septate syrinx cavity extending from c5 to l1, with ... | 2010 | 20379479 |
| radical cystectomy in patients previously treated for localized prostate cancer. | to present outcomes of a contemporary series of patients undergoing radical cystectomy (rc) for bladder cancer after previous treatment for localized cancer of the prostate (cap). | 2010 | 20381130 |
| increase in vertebral body size in postmenopausal women with osteoporosis. | bone geometry plays a prominent role in bone strength. cross-sectional studies have shown that advancing age is associated with increasing diameter of long bones, related to both periostal apposition and endosteal resorption. however, there are few data provided by prospective studies, especially concerning the changes in vertebral body dimensions. the objective of this prospective study was to measure the changes occurring in the vertebral body size of women with postmenopausal osteoporosis. th ... | 2010 | 20381650 |
| post-challenge hematological evaluation with virulent strain of eimeria tenella in broilers immunized with attenuated strain or sporozoite proteins from homologous strain. | hematological parameters were evaluated in broilers immunized and challenged with eimeria tenella. broiler chickens of hubbard strain, females, coccidian-free, were kept in wire cages and inoculated on the third day. the experiment was designed to include five sorts of treatment with three replicates each. t1 was the negative control group, t2 received 500 attenuated sporulated oocysts by gavage, t3 was the positive control, t4 received 50 μg of sporozoite protein + quil a vaccine, and t5 receiv ... | 2010 | 20385052 |
| one-step, zero-background ligation-independent cloning intron-containing hairpin rna constructs for rnai in plants. | *the hairpin-based rna interference (rnai) technique plays an important role in exploring gene function in plants. although there are several methods for making hairpin rna (hprna) constructs, these methods usually need multiple relatively laborious, time-consuming or high-cost cloning steps. here we describe a one-step, zero-background ligation-independent cloning (oz-lic) method for making intron-containing hprna (ihprna) constructs by our vector prnai-lic. *to generate the ihprna constructs w ... | 2010 | 20406406 |
| primary antiphospholipid syndrome and thyroid involvement. | data on thyroid involvement in primary antiphospholipid syndrome are scarce and inconclusive. | 2010 | 20407389 |