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characterization of white tea metabolome: comparison against green and black tea by a nontargeted metabolomics approach.white tea is considered the least processed form of tea and is reported to have a series of potent bioactivities, such as antioxidant, anti-inflammatory, anti-mutagenic, and anti-cancer activities. however, the chemical composition of white tea and the dynamic changes of the metabolites during the manufacturing process are far from clear. in this study, we applied a nontargeted metabolomics approach based on ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass ...201728528106
functional characterizations of β-glucosidases involved in aroma compound formation in tea (camellia sinensis).tea (camellia sinensis) aroma is an important factor affecting tea quality. many tea aroma compounds are present as glycosidically conjugated forms in tea leaves, and can be hydrolyzed by β-glucosidase (β-glu) and β-primeverosidase to release free tea aromas. β-primeverosidase has been identified and functionally characterized, while β-glu has not been identified in tea leaves. in the present study, we established a yeast expression system to recombine csgh1bg1, csgh3bg1, and csgh5bg1, which bel ...201728528101
proteomic analysis of tea plants (camellia sinensis) with purple young shoots during leaf development.tea products made from purple leaves are highly preferred by consumers due to the health benefits. this study developed a proteome reference map related to color changes during leaf growth in tea (camellia sinensis) plant with purple young shoots using two-dimensional electrophoresis (2-de). forty-six differentially expressed proteins were detected in the gel and successfully identified by using maldi-tof/tof-ms. the pronounced changes in the proteomic profile between tender purple leaves (tpl) ...201728520776
expression of key structural genes of the phenylpropanoid pathway associated with catechin epimerization in tea cultivars.catechin epimerization is an important factor affecting tea catechin compositions and thereby tea quality. however, a lack of tea germplasms with high non-epicatechins limits relative research. here, a tea cultivar y510 with high non-epicatechins was firstly reported and used for catechin and rna sequencing (rna-seq) analysis. results showed that the (-)-gallocatechin gallate and (+)-catechin (c) contents in y510 were at least 136 and 6 times higher than those in fudingdabaicha and 0306i, but th ...201728515736
characterization of l-theanine excitatory actions on hippocampal neurons: toward the generation of novel n-methyl-d-aspartate receptor modulators based on its backbone.l-theanine (or l-γ-n-ethyl-glutamine) is the major amino acid found in camellia sinensis. it has received much attention because of its pleiotropic physiological and pharmacological activities leading to health benefits in humans, especially. we describe here a new, easy, efficient, and environmentally friendly chemical synthesis of l-theanine and l-γ-n-propyl-gln and their corresponding d-isomers. l-theanine, and its derivatives obtained so far, exhibited partial coagonistic action at n-methyl- ...201728511005
short-term effects of green tea chronotherapy on the metabolic homeostasis of mice on different diets.biological rhythms can be defined as changes in physiological or behavioral variables that repeat at certain time intervals. rhythms that last approximately 24 h are referred to as circadian rhythms. modern lifestyles have drastically affected human habits, as well as the population's eating habits. these changes have generated an epidemic of metabolic syndromes, such as obesity and diabetes. in an attempt to combat obesity, populations have attempted to use many different herbal remedies and pl ...201728510251
camellia sinensis increased apoptosis on u2os osteosarcoma cells and wound healing potential on nih3t3 fibroblast cells.camellia sinensis (cs) is a plant which is rich in polyphenols and has antioxidant, antiinflammatory, antimutagenic, anticarcinogenic and antibacterial activities. in this study, two different methanol extracts (cs-i and cs-ii) were prepared from the leaf of c. sinensis in order to investigate the wound healing and anticancer activities. total phenolic content and antioxidant activity of the extracts were determined. wound healing effects of cs extracts were evaluated by using masson's trichrome ...201728509991
quantitative succinyl-proteome profiling of camellia sinensis cv. 'anji baicha' during periodic albinism.lysine succinylation is a novel dynamic and evolutionarily conserved post-translational modification (ptm) that regulates various biological processes. 'anji baicha' is an albino tea variety that exhibits temperature-based variability of leaf colour and amino acid concentrations. however, the mechanism underlying albinism in 'anji baicha' has not been investigated at the level of succinylation. here, we identify 3530 lysine succinylation sites mapped to 2132 proteins in 'anji baicha', representi ...201728500349
nickel nanoparticle synthesis using camellia sinensis as reducing and capping agent: growth mechanism and photo-catalytic activity evaluation.recently, the biosynthesis of nanoparticle attracted the attention of scientific community due to its simplicity, ease and eco-friendly nature. in the present study, camellia sinensis (c. sinensis) leaves extract was employed for the synthesis of nickel nanoparticles (ninps). the fabricated ninps were characterized by scanning electron microscopy (sem) and energy-dispersive x-ray (edx) and x-ray diffraction techniques. the photocatalytic activity (pca) was evaluated by degrading crystal violet ( ...201728495625
artemisinin-luminol chemiluminescence for forensic bloodstain detection using a smart phone as a detector.forensic luminol chemiluminescence test is one of the most sensitive and popular methods for the determination of latent bloodstains. it mainly uses hydrogen peroxide or sodium perborate as coreactants. the easy decomposition of hydrogen peroxide and sodium perborate in the presence of many ions significantly affects the selectivity. artemisinin is a natural peroxide that is quite stable in the presence of common ions. in the present study, artemisinin has been exploited for the forensic bloodst ...201728492080
transcriptome and metabolite analysis identifies nitrogen utilization genes in tea plant (camellia sinensis).applied nitrogen (n) fertilizer significantly increases the leaf yield. however, most n is not utilized by the plant, negatively impacting the environment. to date, little is known regarding n utilization genes and mechanisms in the leaf production. to understand this, we investigated transcriptomes using rna-seq and amino acid levels with n treatment in tea (camellia sinensis), the most popular beverage crop. we identified 196 and 29 common differentially expressed genes in roots and leaves, re ...201728490757
effects of dietary green tea (camellia sinensis l.) supplementation on growth performance, lipid metabolism, and antioxidant status in a sturgeon hybrid of sterlet (huso huso ♂ × acipenser ruthenus ♀) fed oxidized fish oil.lipid content of diet is very susceptible to oxidation, especially when stored for a long time, so for evaluating protective effects of green tea in fish received oxidized oil, this study was done. lipid content of diet was replaced by oxidized fish oil (ofo) in 0, 50, and 100%. green tea extract (gte) was added to diet in three levels, 0, 5, and 100 mg/kg giving a total of nine experimental diets. two hundred and seventy sturgeon hybrid of sterlet (huso huso ♀ × acipenser ruthenus ♂) with initi ...201728488192
nitric oxide mediates brassinosteroid-induced flavonoid biosynthesis in camellia sinensis l.flavonoids are one of the key secondary metabolites determining the quality of tea. although exogenous brassinosteroid (br), a steroidal plant hormone, can stimulate polyphenol biosynthesis in tea plants (camellia sinensis l.), the relevance of endogenous br in flavonoid accumulation and the underlying mechanisms remain largely unknown. here we show that br enhances flavonoid concentration in tea leaves by inducing an increase in the endogenous concentration of nitric oxide (no). notably, exogen ...201728482335
probable benefits of green tea with genetic implications.tea is produced from the camellia sinensis plant and can generally be divided into categories based on how they are processed. in general, green tea that is unfermented c. sinensis has been considered superior to black tea in health benefits. it contains a unique set of catechins that possess biological activity as antioxidant, anti-inflammatory and antiproliferative, which is potentially significant to the prevention and treatment of various forms of diseases. oral cavity oxidative stress and i ...201728479696
oak kombucha protects against oxidative stress and inflammatory processes.black tea infusion is the common substrate for preparing kombucha; however other sources such as oak leaves infusions can be used for the same purpose. almost any white oak species have been used for medicinal applications by some ethnic groups in mexico and could be also suitable for preparing kombucha analogues from oak (kao). the objective of this research was to investigate the antioxidant activity and anti-inflammatory effects of kao by examining its modulation ability on macrophage-derived ...201728476604
the tea tree genome provides insights into tea flavor and independent evolution of caffeine biosynthesis.tea is the world's oldest and most popular caffeine-containing beverage with immense economic, medicinal, and cultural importance. here, we present the first high-quality nucleotide sequence of the repeat-rich (80.9%), 3.02-gb genome of the cultivated tea tree camellia sinensis. we show that an extraordinarily large genome size of tea tree is resulted from the slow, steady, and long-term amplification of a few ltr retrotransposon families. in addition to a recent whole-genome duplication event, ...201728473262
molecular link between leaf coloration and gene expression of flavonoid and carotenoid biosynthesis in camellia sinensis cultivar 'huangjinya'.'huangjinya' is an excellent albino tea germplasm cultivated in china because of its bright color and high amino acid content. it is light sensitive, with yellow leaves under intense light while green leaves under weak light. as well, the flavonoid and carotenoid levels increased after moderate shading treatment. however, the mechanism underlying this interesting phenomenon remains unclear. in this study, the transcriptome of 'huangjinya' plants exposed to sunlight and shade were analyzed by hig ...201728596773
bioavailability of black tea theaflavins: absorption, metabolism, and colonic catabolism.data obtained with in vitro fecal incubations and a feeding study indicate black tea theaflavin and its galloyl derivatives are not absorbed in detectable amounts in either the upper or lower gastrointestinal tract. the theaflavin skeleton is comparatively resistant to degradation by colonic bacteria with a 67% recovery being obtained after a 24 h incubation, which yielded 21 phenolic and aromatic catabolites. the theaflavin galloyl moiety was removed by the microbiota, and the released gallic a ...201728595385
camellia sinensis prevents perinatal nicotine-induced neurobehavioral alterations, tissue injury, and oxidative stress in male and female mice newborns.nicotine exposure during pregnancy induces oxidative stress and leads to behavioral alterations in early childhood and young adulthood. the current study aimed to investigate the possible protective effects of green tea (camellia sinensis) against perinatal nicotine-induced behavioral alterations and oxidative stress in mice newborns. pregnant mice received 50 mg/kg c. sinensis on gestational day 1 (pd1) to postnatal day 15 (d15) and were subcutaneously injected with 0.25 mg/kg nicotine from pd1 ...201728588748
protective effects of green tea on olanzapine-induced-metabolic syndrome in rats.atypical antipsychotics particularly olanzapine are associated with obesity and serious metabolic disturbances. as green tea (camellia sinensis) is generally associated with beneficial effects on obesity and other metabolic disturbances, this study was undertaken to evaluate the effect of green tea aqueous extract (gtae) on olanzapine induced weight gain and metabolic abnormalities in rats. male wistar rats were divided into eight groups: control, olanzapine (5mg/kg/day, ip.), gtae (25, 50 and 1 ...201728586744
a randomized, double-blind, placebo-controlled clinical trial examining the effects of green tea extract on systemic lupus erythematosus disease activity and quality of life.antiinflammatory and immunomodulatory benefit of green tea (camellia sinensis) in autoimmune disease has been proven in recent studies. the objective of this study was to assess the effects of green tea on disease activity and quality of life in systemic lupus erythematosus patients. a randomized controlled trial on subjects with lupus was conducted, and 68 patients in the age range of 39.1 ± 10.3 years and body mass index of 25.7 ± 5.21 kg/m2 completed the 12-week study. patients were randomly ...201728585735
the synergistic potential of various teas, herbs and therapeutic drugs in health improvement: a review.tea is one of the most widely consumed non-alcoholic beverages in the world next to water. it is classified as camellia sinensis and non-camellia sinensis (herbal teas). the common bioactive compounds found mainly in green teas are flavan-3-ols (catechins) (also called flavanols), proanthocyanidins (tannins) and flavonols. black tea contains theaflavins and thearubigins and white tea contains l-theanine and gamma-aminobutyric acid (gaba), while herbal teas contain diverse polyphenols. phytochemi ...201728585285
a case of green tea (camellia sinensis) imbibement causing possible anaphylaxis. 201728583266
high-theabrownins instant dark tea product by aspergillus niger via submerged fermentation: α-glucosidase and pancreatic lipase inhibition and antioxidant activity.theabrownins (tb) are bioactive components that are usually extracted from chinese dark tea, in which they are present at low concentrations. the present study aimed to produce an instant dark tea high in theabrownins via submerged fermentation by the fungus aspergillus niger. three fermentation parameters that affect theabrownins content (i.e. inoculum size, liquid-solid ratio and rotation speed) were optimized using response surface methodology.201728422292
cymbopogon citratus and camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo.cancer cells are reported to have elevated levels of reactive oxygen species (ros) and are highly dependent on cellular defense mechanisms against oxidative stress. numerous nutraceuticals and natural polyphenolic compounds have a wide range of abilities to alter cellular redox states with potential implications in various diseases. furthermore, therapeutic options for cancers are mostly nonselective treatments including genotoxic or tubulin-targeting compounds. some of the natural extracts, con ...201729340014
influence of particle size and extraction solvent on antioxidant properties of extracts of tea, ginger, and tea-ginger blend.the influence of particle size and extraction solvent on the antioxidant properties of aqueous and ethanolic extracts of tea (camellia sinensis), ginger (zingiber officinale), and tea-ginger (2:1) blend was investigated. the powder sizes studied were 0.425, 0.710, and 1.180 mm. extracts were analyzed for dpph radical scavenging activity, abts radical scavenging activity, total phenol content (tpc), iron chelating activity, total flavonoid content, and peroxide scavenging activity. the powder wit ...201729188046
nutritional supplements and herbal medicines for women with polycystic ovary syndrome; a systematic review and meta-analysis.polycystic ovary syndrome (pcos) is a common, reproductive endocrinopathy associated with serious short and long term health risks. many women with pcos use ingestible complementary medicines. this systematic review examined the effect on menstrual regulation and adverse effects from randomised controlled trials.201729178904
colletotrichum gloeosporioides- contaminated tea infusion blocks lipids reduction and induces kidney damage in mice.when the homogenate of fresh tea tree leaves was fermented to produce black tea beverage, the colletotrichum gloeosporioides (main pathogen or endophyte of camellia sinensis) may be mixed into the fermentation liquor. however, it was unclear whether c. gloeosporioides-contaminated tea beverage would damage human health. therefore, we investigated the changes of functional components and the influences on mice. c. gloeosporioides was added to the green tea infusion. after cultivation of 48 h, tea ...201729163391
proteome and acetyl-proteome profiling of camellia sinensis cv. 'anjin baicha' during periodic albinism reveals alterations in photosynthetic and secondary metabolite biosynthetic pathways.tea leaf color is not only important from an aesthetics standpoint but is also related to tea quality. to investigate the molecular mechanisms that determine tea leaf color, we examined camellia sinensis cv. 'anjin baicha' (an albino tea cultivar) by tandem mass tag isobaric labeling to generate a high-resolution proteome and acetyl-proteome atlas of three leaf developmental stages. we identified a total of 7,637 proteins and quantified 6,256; of these, 3,232 were classified as differentially ac ...201729312376
fat burner-induced acute liver injury: case series of four patients.dietary supplements known as "fat burners" are typically marketed with claims of increasing energy expenditure through alterations in fat metabolism. they are marketed as natural products and their use is thus perceived as a safe body weight reduction strategy. we report on five episodes of liver injury in four patients. liver injury was associated with consumption of different commercially available fat burners: green tea extract (camellia sinensis), garcinia gummi-gutta, green coffee beans, an ...201729310849
contamination of tea and tea infusion with polycyclic aromatic hydrocarbons.the aim of this work was to validate the method of determination of polycyclic aromatic hydrocarbons (pahs), i.e., benzo(a)pyrene and sum of benzo(a)pyrene, benz(a)anthracene, benzo(b)fluoranthene and chrysene in different types of tea, as well as to assess the transfer of these contaminants from tea to tea infusion. the research materials were popular types of black, green, red and white tea. quantitative and qualitative determination of pahs was performed by high performance liquid chromatogra ...201729283369
comparative effect of camellia sinensis teas on object recognition test deficit and metabolic changes induced by cafeteria diet.consumption of high-fat and high-sugar diets in western countries has increased significantly causing major global health problems including metabolic syndrome and obesity. in addition, studies have suggested that obesity can lead to learning and memory deficits. in this context, the use of natural compounds with low costs, minor side effects and increased antioxidant activity, such as teas, could reduce the damages induced by obesity. we investigated the effect of white, green, red, and black t ...201729280418
shade changing effectiveness of plasdone and blue covarine-based whitening toothpaste on teeth stained with chlorhexidine and black tea.this study evaluated the effectiveness of toothbrushing with whitening toothpaste in altering the shade of stained human enamel.201729279667
green synthesis palladium nanoparticles mediated by white tea (camellia sinensis) extract with antioxidant, antibacterial, and antiproliferative activities toward the human leukemia (molt-4) cell line.among nanoparticles used for medical applications, palladium nanoparticles (pdnps) are among the least investigated. this study was undertaken to develop pdnps by green synthesis using white tea (w.tea; camellia sinensis) extract to produce the pd@w.tea nps. the pd@w.tea nps were characterized by uv-vis spectroscopy and x-ray diffractometry, and evaluated with transmission electron microscopy (tem) and scanning electron microscopy (sem). the pd@w.tea nps were spherical (size 6-18 nm) and contain ...201729276385
external morphology of the mouthparts and observations on behavior of tuckerella japonica on camellia sinensis in the continental usa.tuckerella japonica ehara (acari: tetranychoidea: tuckerellidae) was found on stems of seedling plants of camellia sinensis (l.) o. kuntze (theaceae) in the continental usa. this mite is able to pierce exposed green periderm tissue with its paired stylets on 1- to 3- or 4-year-old stems where the outer bark had split longitudinally. the mite was not found on branches older than 3 or 4 years, where splitting diminished and, eventually, a uniform covering of bark was formed. the mouthparts of t. j ...201729255965
effect of various teas on color stability of resin composites.to investigate the effect of various teas on color stability of resin composites.201729251455
chitosan-induced immunity in camellia sinensis (l.) o. kuntze against blister blight disease is mediated by nitric-oxide.blister blight disease, caused by an obligate biotrophic fungal pathogen, exobasidium vexans massee is posing a serious threat for tea cultivation in asia. as the use of chemical pesticides on tea leaves substantially increases the toxic risks of tea consumption, serious attempts are being made to control such pathogens by boosting the intrinsic natural defense responses against invading pathogens in tea plants. in this study, the nature and durability of resistance offered by chitosan and the p ...201728412634
an induced extrinsic tooth stain prevention model to investigate whitening potential of sugar-free chewing gums.to establish an accelerated clinical test method to evaluate the effectiveness of sugar-free gums in prevention of the formation of extrinsic stains when chewed over a 2-week period in conjunction with daily tooth brushing. a secondary objective was to compare three methods for measuring extrinsic stain.201729251453
two new species of <i>mycterothrips</i> (thysanoptera: thripidae) from southwestern china.mycterothrips gongshanensis sp.n. and m. yelangi sp.n. are described from southwestern china. both species have been collected from tea (camellia sinensis), and m. gongshanensis sp.n. is a potential pest in tea gardens. an identification key is provided to the mycterothrips species recorded from china.201729245515
metabolic characterization of the anthocyanidin reductase pathway involved in the biosynthesis of flavan-3-ols in elite shuchazao tea (camellia sinensis) cultivar in the field.anthocyanidin reductase (anr) is a key enzyme in the anr biosynthetic pathway of flavan-3-ols and proanthocyanidins (pas) in plants. herein, we report characterization of the anr pathway of flavan-3-ols in shuchazao tea (camellia sinesis), which is an elite and widely grown cultivar in china and is rich in flavan-3-ols providing with high nutritional value to human health. in our study, metabolic profiling was preformed to identify two conjugates and four aglycones of flavan-3-ols: (-)-epigalloc ...201729244739
green tea polyphenol egcg causes anti-cancerous epigenetic modulations in acute promyelocytic leukemia cells.green tea (camellia sinensis) catechin epigallocatechin-3-gallate (egcg) has been shown to possess diverse anti-cancerous properties. we demonstrated egcg ability to inhibit acute promyelocytic leukemia (apl) cell proliferation and cause apoptosis. in addition, quantitative real-time polymerase chain reaction (rt-qpcr) analysis revealed elevated expression of genes associated with cell cycle arrest and differentiation (p27, pcaf, c/ebpα, and c/ebpɛ). furthermore, egcg caused anti-cancerous epige ...201728641467
theaflavins from black tea affect growth, development, and motility in dictyostelium discoideum.theaflavins, flavonoids found in black tea, exhibit a variety of health-promoting activities, but the mechanisms by which they act are not clear. here, we assess the effects of black tea extract and isolated theaflavins on dictyostelium discoideum, a model organism exhibiting an unusual life cycle relying on conserved pathways involved in human disease. dictyostelium has been used to characterize the activities of numerous bioactive small molecules, including catechins, from which theaflavins ar ...201728711497
the cshsp17.2 molecular chaperone is essential for thermotolerance in camellia sinensis.small heat shock proteins (shsps) play important roles in responses to heat stress. however, the functions of shsps in tea plants (camellia sinensis) remain uncharacterized. a novel shsp gene, designated cshsp17.2, was isolated from tea plants. subcellular localization analyses indicated that the cshsp17.2 protein was present in the cytosol and the nucleus. cshsp17.2 expression was significantly up-regulated by heat stress but was unaffected by low temperature. the cshsp17.2 transcript levels in ...201728450727
lactic fermentation as an efficient tool to enhance the antioxidant activity of tropical fruit juices and teas.tropical fruits like pineapple, papaya, mango, and beverages such as green or black teas, represent an underestimated source of antioxidants that could exert health-promoting properties. most food processing technologies applied to fruit beverages or teas result in an impairment of inherent nutritional properties. conversely, we hypothesise that lactic acid fermentation may constitute a promising route to maintain and even improve the nutritional qualities of processed fruits. using specific gro ...201728489022
in vitro anti-malassezia activity of castanea crenata shell and oil-soluble glycyrrhiza extracts.a new shampoo with anti-malassezia properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options.201728566909
phytoestrogen-rich natural preparation for treatment of climacteric syndrome and atherosclerosis prevention in perimenopausal women.the present study evaluated the risks and benefits of phytoestrogen treatment in healthy perimenopausal women in relation to the dynamics of climacteric syndrome and progression of atherosclerosis. study participants were treated with placebo or phytoestrogen-rich natural preparation karinat based on grape (vitis vinifera) seeds, green tea (camellia sinensis) leaves, hop (hunulus lupulus) cone powder and garlic (allium sativum) powder. the dynamics of climacteric syndrome was evaluated by kupper ...201728593720
efficacy and tolerability of phytomedicines in multiple sclerosis patients: a review.multiple sclerosis (ms) is a chronic inflammatory and demyelinating disorder of the central nervous system (cns) that can cause cognition, mobility, and sensory impairments. it is considered one of the most common non-traumatic causes of disability in the world. the aim of the present article was to review the clinical evidence related to medicinal plants in the management of ms symptoms. electronic databases, including the cochrane library, pubmed, and scopus, were searched for entries from 196 ...201728948486
inhibition of cyclic adenosine monophosphate-specific phosphodiesterase by various food plant-derived phytotherapeutic agents.background: phosphodiesterases (pdes) play a major role in the regulation of cyclic adenosine monophosphate (camp)- and cyclic guanosine monophosphate (cgmp)-mediated pathways. their inhibitors exhibit anti-inflammatory, vasodilatory and antithrombotic effects. therefore, consumption of foods with pde-inhibiting potential may possess beneficial influence on the risk of cardiovascular diseases. methods: four plant extracts (arbutus unedo, camellia sinensis, cynara scolymus, zingiber officinale) w ...201729113064
uplc-q-exactive orbitrap/ms-based lipidomics approach to characterize lipid extracts from bee pollen and their in vitro anti-inflammatory properties.bee pollen (bp) is collected by honeybees from flower pollen mixed with nectar and its secretions with extensive nutritional and therapeutic properties. lipids are known to be critical contributors for the therapeutic effects of bp and vary depending on different plant sources; however, lipid profiles of bp are not available. here, an uplc-q-exactive orbitrap/ms method was established for comprehensive lipidomics analysis of bp derived from three major nectar plants (brassica campestris l., came ...201728737913
cellular injury to 1- to 3+-year-old stems of camellia sinensis by tuckerella japonica.tuckerella japonica ehara (acari: tuckerellidae) feeds on predigested plant cells beneath exposed periderm tissue of 1- to 3+-year-old stems of camellia sinensis (l.) o. kuntze (theaceae) where longitudinal bark splitting occurs. control samples from these tissues were compared with areas fed upon by t. japonica adults and immatures to characterize types of cellular injury. stylet diameters ranged from 1.6 to 2.3 µm and were consistent with observed stylet punctures in the stems. mite saliva was ...201729188400
functional analysis of an uridine diphosphate glycosyltransferase involved in the biosynthesis of polyphenolic glucoside in tea plants (camellia sinensis).polyphenols are one of the largest groups of compounds that confer benefits to the health of plants and humans. flavonol glycosides are a major ingredient of polyphenols in camellia sinensis. flavonol-3-o-glycosides are characteristic astringent taste compounds in tea infusion. a polyphenolic glycosyltransferase (csugt72am1) belonging to cluster iiib was isolated from the tea plant. the full-length cdna of csugt72am1 is 1416 bp. it encodes 472 amino acids with a calculated molecular mass of 50.9 ...201729161813
functional characterization of salicylic acid carboxyl methyltransferase from camellia sinensis, providing the aroma compound of methyl salicylate during the withering process of white tea.methyl salicylate (mesa) is one of the volatile organic compounds (vocs) that releases floral scent and plays an important role in the sweet flowery aroma of tea. during the withering process for white tea producing, mesa was generated by salicylic acid carboxyl methyltransferase (samt) with salicylic acid (sa), and the specific floral scent was formed. in this study, we first cloned a cssamt from tea leaves (genbank accession no. mg459470) and used escherichia coli and saccharomyces cerevisiae ...201729160698
identification of drought-responsive mirnas and physiological characterization of tea plant (camellia sinensis l.) under drought stress.drought stress is one of the major natural challenges in the main tea-producing regions of china. the tea plant (camellia sinensis) is a traditional beverage plant whose growth status directly affects tea quality. recent studies have revealed that micrornas (mirnas) play key functions in plant growth and development. although some mirnas have been identified in c. sinensis, little is known about their roles in the drought stress response of tea plants.201729157225
comparative proteomics reveals the physiological differences between winter tender shoots and spring tender shoots of a novel tea (camellia sinensis l.) cultivar evergrowing in winter.a recently discovered tea [camellia sinensis (l.) o. kuntze] cultivar can generate tender shoots in winter. we performed comparative proteomics to analyze the differentially accumulated proteins between winter and spring tender shoots of this clonal cultivar to reveal the physiological basis of its evergrowing character during winter.201729157222
genome-wide identification of conserved and novel micrornas in one bud and two tender leaves of tea plant (camellia sinensis) by small rna sequencing, microarray-based hybridization and genome survey scaffold sequences.micrornas (mirnas) are important for plant growth and responses to environmental stresses via post-transcriptional regulation of gene expression. tea, which is primarily produced from one bud and two tender leaves of the tea plant (camellia sinensis), is one of the most popular non-alcoholic beverages worldwide owing to its abundance of secondary metabolites. a large number of mirnas have been identified in various plants, including non-model species. however, due to the lack of reference genome ...201729157210
phenolic compounds as natural and multifunctional anti-obesity agents: a review.prevalence of obesity worldwide has reached pandemic proportions. despite the increasing evidence in the implication of phenolic compounds in obesity management, the real effect is not completely understood. the available in vitro and in vivo studies have demonstrated the implication of phenolic compounds in: lowering food intake, decreasing lipogenesis, increasing lipolysis, stimulating fatty acids β-oxidation, inhibiting adipocyte differentiation and growth, attenuating inflammatory responses ...201729156939
digestion under saliva, simulated gastric and small intestinal conditions and fermentation in vitro of polysaccharides from the flowers of camellia sinensis induced by human gut microbiota.in the present study, digestion under saliva, simulated gastric and small intestinal conditions and fermentation in vitro of polysaccharides from the flowers of camellia sinensis (tfps) by human gut microbiota were investigated. the results indicated that human saliva and simulated gastric and intestinal juices had no effect on tfps, while tfps could be utilized by human fecal microbiota, which was proved from the decreased molecular weight and lower content of total or reducing sugars after fer ...201729143827
comparison of the effects of three tea cultivars (camellia sinensis l.) on nitric oxide production and aortic soluble guanylate cyclase expression in high-salt diet-fed spontaneously hypertensive rats.studies have suggested that the consumption of green tea reduces the risk of cardiovascular diseases. although epigallocatechin gallate (egcg) is the best studied active substance characteristic of green tea, previous results on egcg do not appear sufficient to explain completely the mechanism of cardiovascular protection by green tea. therefore, we investigated the effect of three different tea cultivars, "yabukita," "sofu," and "sunrouge," which have characteristic flavonoid compositions, on t ...201729225315
comparative analysis of the response and gene regulation in cold resistant and susceptible tea plants.cold environment is the main constraint for tea plants (camellia sinensis) distribution and tea farming. we identified two tea cultivars, called var. sinensis cv. shuchazao (scz) with a high cold-tolerance and var. assamica cv. yinghong9 (yh9) with low cold-tolerance. to better understand the response mechanism of tea plants under cold stress for improving breeding, we compared physiological and biochemical responses, and associated genes expression in response to 7-day and 14-day cold acclimati ...201729211766
tracking residual organochlorine pesticides (ocps) in green, herbal, and black tea leaves and infusions of commercially available tea products marketed in poland.the content of residual organochlorine pesticides (ocps) was examined in green, herbal, and black tea leaves as well as in their infusions prepared from tea products marketed in the main supermarkets in poland. it was found that the detected mean levels of organochlorine residues in tea leaves ranged from <lod to 16.36 ng g-1 dry weight. among hexachlorocyclohexane isomers, γ-hch in green tea occurred in the highest concentrations. among dichlorodiphenyltrichloroethane (ddt) metabolites the high ...201729210611
an in vitro study to compare the effect of different types of tea with chlorhexidine on streptococcusmutans.tea is the second most commonly consumed beverage in the world after water. the leaf and bud of the plant camellia sinensis produces tea. the different forms of tea are 'non-fermented' green tea, 'semi-fermented' oolong tea and 'fermented' black tea according to the manufacturing process. streptococcus mutans is the main causative organism in dental caries and plaque formation.201729207823
development of a rapid and simple method to remove polyphenols from plant extracts.polyphenols are secondary metabolites of plants, which are responsible for prevention of many diseases. polyvinylpolypyrrolidone (pvpp) has a high affinity towards polyphenols. this method involves the use of pvpp column to remove polyphenols under centrifugal force. standards of gallic acid, epigallocatechin gallate, vanillin, and tea extracts (camellia sinensis) were used in this study. pvpp powder was packed in a syringe with different quantities. the test samples were layered over the pvpp c ...201729201056
pre-treated theaflavin-3,3'-digallate has a higher inhibitory effect on the hct116 cell line.the pro-apoptotic and inhibitory effects of the aflavin-3,3'-digallate (tfdg), which is the typical pigment in black tea, have been demonstrated in many cancer cell lines. however, tfdg is not stable in general culture conditions. so, to what extent tfdg or which degradation products of tfdg play an antitumor role is still unclear. in this study, we evaluated the effect of different treatments of tfdg on hct116 cells. compared with the control, both tfdg and o-tfdg (the tfdg that was pre-incubat ...201729200992
antioxidant and anti-inflammatory properties of ilex guayusa tea preparations: a comparison to camellia sinensis teas.ilex guayusa tea preparations are now commercially available as runa tea. little is known regarding the antioxidant and anti-inflammatory bioactivities of this tea. the i. guayusa teas had a total polyphenolic content between 54.39 and 67.23 mg gae per g dry mass and peroxyl radical scavenging capacities between 1773.41 and 2019 μmol te per g dry mass, nearly half of that for the camellia sinensis teas. the i. guayusa teas afforded 60-80% protection from oxidative stress in the caco-2 cellular a ...201729134218
functional characterization of epitheaflagallin 3-o-gallate generated in laccase-treated green tea extracts in the presence of gallic acid.epitheaflagallin (etfg) and epitheaflagallin 3-o-gallate (etfgg) are minor polyphenols in black tea extract that are enzymatically synthesized from epigallocatechin (egc) and epigallocatechin gallate (egcg), respectively, in green tea extract via laccase oxidation in the presence of gallic acid. the constituents of laccase-treated green tea extract in the presence of gallic acid are thus quite different from those of nonlaccase-treated green tea extract: egc and egcg are present in lower concent ...201729131612
proteomic analysis of camellia sinensis (l.) reveals a synergistic network in the response to drought stress and recovery.drought is a crucial limiting factor for tea yield and quality. to systematically characterize the molecular response of tea plants to drought stress and its capacity to recover, we used itraq-based comparative proteomic approach to investigate the effects of drought on protein expression profiles in tea seedlings subjected to different drought treatments. a total of 3274 proteins were identified, of which 2169 and 2300 showed differential expressions during drought and recovery, respectively. f ...201729096085
functional analysis of two flavanone-3-hydroxylase genes from camellia sinensis: a critical role in flavonoid accumulation.flavonoids are major secondary metabolites in camellia sinensis. flavanone-3-hydroxylase (f3h) is a key enzyme in flavonoid biosynthesis in plants. however, its role in the flavonoid metabolism in c. sinensis has not been well studied. in this study, we cloned two f3hs from c. sinensis, named csf3ha and csf3hb, where csf3ha containing 1107 bases encoded 368 amino acids, and csf3hb containing 1071 bases encoded 357 amino acids. enzymatic activity analysis showed both recombinant csf3h enzymes in ...201729088063
comparative assessment of antibacterial efficacy of aqueous extract of commercially available black, green, and lemon tea: an in vitro study.the objective of this study is to determine and compare antibacterial efficacy of aqueous extracts of black, green, and lemon tea of a commercially available brand.201729085267
improving the quality of fermented black tea juice with oolong tea infusion.fresh tea leaves were crushed into juice and then fermented (oxidation) to obtain fermented black tea juice, which can be used to prepare black tea beverage. the effects of addition of oolong tea infusion or tossing of tea leaves on the sensory quality and theaflavins (tfs) concentration of fermented black tea juice were investigated. the results showed that both addition of tea infusion and tossing of fresh tea leaves increased the tfs/thearubigins (trs) ratio and improved the sensory quality o ...201729085133
quantum-dot-based lateral flow immunoassay for detection of neonicotinoid residues in tea leaves.neonicotinoid insecticides are commonly used for pest control on tea plantations as a result of their broad-spectrum activity. however, neonicotinoid residues released from tea leaves into tea infusions pose a dietary risk to consumers. therefore, a rapid, sensitive, and reliable on-site detection method for neonicotinoids is needed. we developed a quantum-dot-based fluorescent lateral flow immunochromatographic strip (lfics) combined with a broad-specific antibody for detection of typical neoni ...201729077402
actual daily intakes of tea catechins and thier estimation according to four season 3 day weighed dietary records and a short food frequency questionnaire among japanese men and womenbackground: tea catechins are considered to be important preventive factors of cancer on several organs; however, the relationships of the actual daily intakes (adis) on the preventive effects have not been adequately addressed. we measured the adis of tea catechins as annual averages derived from every their ingested cups recorded by each subject, and the estimation models were established considering tea origin. methods: fifty-nine japanese men and women completed four season 3 day weighed die ...201729072829
pupation behaviors and emergence successes of ectropis grisescens (lepidoptera: geometridae) in response to different substrate types and moisture contents.ectropis grisescens warren (lepidoptera: geometridae) is one of the most severe pests of tea plants in china. this species commonly pupates in soil; however, little is known about its pupation ecology. in the present study, choice and no-choice tests were conducted to investigate the pupation behaviors and emergence success of e. grisescens in response to different substrates (sand, sandy loam 1, sandy loam 2, and silt loam) and moisture contents (5, 20, 35, 50, 65, and 80%). moisture-choice bio ...201729069472
multimycotoxin lc-ms/ms analysis in tea beverages after dispersive liquid-liquid microextraction (dllme).the aim of the present study was to develop a multimycotoxin liquid chromatography tandem mass spectrometry (lc-ms/ms) method with a dispersive liquid-liquid microextraction procedure (dllme) for the analysis of afs, 3adon, 15adon, niv, ht-2, t-2, zea, ota, enns, and bea in tea beverages and to evaluate their mycotoxin contents. the proposed method was characterized in terms of linearity, limits of detection (lods), limits of quantification (loqs), recoveries, repeatability (intraday precision), ...201729068686
the roles of epigallocatechin-3-gallate in the treatment of neuropathic pain: an update on preclinical in vivo studies and future perspectives.neuropathic pain (np) is a complex and chronic disease caused by lesions or defects of the somatosensory nervous system. the treatments normally used for managing np usually lack efficacy. several animal models of np have been engineered in order to understand the molecular mechanisms underlying np and to find alternative molecules to use as new therapeutic agents. preclinical in vivo studies identified the epigallocatechin-3-gallate (egcg), a main active component of green tea (camellia sinensi ...201729066865
comprehensive lipidome-wide profiling reveals dynamic changes of tea lipids during manufacturing process of black tea.as important biomolecules in camellia sinensis l., lipids undergo substantial changes during black tea manufacture, which is considered to contribute to tea sensory quality. however, limited by analytical capacity, detailed lipid composition and its dynamic changes during black tea manufacture remain unclear. herein, we performed tea lipidome profiling using high resolution liquid chromatography coupled to mass spectrometry (lc-ms), which allows simultaneous and robust analysis of 192 individual ...201729058896
development of a novel herbal formulation to inhibit biofilm formation in toxigenic vibrio cholerae.vibrio cholerae, a causative agent of the waterborne disease cholera, still threatens a large proportion of world's population. the role of biofilm formation in v. cholerae pathogenesis is well established, as it provides the bacterium enhanced tolerance to antimicrobial agents and increased transmission. in the present study, four medicinal plants used in traditional medicines with antidiarrheal properties were evaluated for its antibiofilm activity. methanol extracts of these plants (centella ...201729053421
characterization of molecular structures of theaflavins and the interactions with bovine serum albumin.in this study, theaflavins (tf1, tf2a, tf2b and tf3) were prepared from black tea and their interaction with bovine serum albumin (bsa) was explored by fluorescence and cd spectroscopy. the results showed that the structures of theaflavins exhibited significant effects on the binding/quenching process, and the binding affinity increased with the increase of molecular weight of theaflavins and the presence of galloyl moiety. the quenching effects showed a sequence as tf3 > tf2a > tf2b > tf1, demo ...201729051637
genome-wide identification of micrornas responsive to ectropis oblique feeding in tea plant (camellia sinensis l.).the tea plant (camellia sinensis l.) is vulnerable to the geometrid ectropis oblique; although micrornas (mirnas) are important for plant growth, development and stress response, the function of mirnas in the response of c. sinensis to stress from e. oblique is unclear. to identify e. oblique stress-responsive mirnas and their target genes in tea plant, three small rna libraries were constructed from leaves subjected to mechanical wounding (mw), geometrid attack (ga) and from healthy control (ck ...201729051614
draft genome sequence of paenibacillus sp. xy044, a potential plant growth promoter isolated from a tea plant.paenibacillus sp. xy044 is an endophytic bacterium isolated from the stem of a tea plant (camellia sinensis cv. maoxie). here, we present the draft genome sequence of xy044, which includes genes encoding features related to plant growth promotion and biocontrol.201728912334
draft genome sequence of streptomyces sp. xy006, an endophyte isolated from tea (camellia sinensis).streptomyces sp. xy006 is an endophytic bacterium isolated from the young leaf material of the tea plant (camellia sinensis). the draft genome consists of 8.2 mb and encodes 7,415 putative open reading frames. this strain is found to contain a high capacity for the production of natural products.201728912322
dna barcode and identification of the varieties and provenances of taiwan's domestic and imported made teas using ribosomal internal transcribed spacer 2 sequences.the major aim of made tea identification is to identify the variety and provenance of the tea plant. the present experiment used 113 tea plants [camellia sinensis (l.) o. kuntze] housed at the tea research and extension substation, from which 113 internal transcribed spacer 2 (its2) fragments, 104 trnl intron, and 98 trnl-trnf intergenic sequence region dna sequences were successfully sequenced. the similarity of the its2 nucleotide sequences between tea plants housed at the tea research and ext ...201728911667
antibacterial and antiadhesive activities of extracts from edible plants against soft drink spoilage by asaia spp.this study was conducted to investigate the antibacterial and antiadhesive activities of ethanol extracts from five edible plant parts: cinnamon bark ( cinnamomum zeylanicum ), licorice root ( glycyrrhiza radix ), nettle leaves ( urtica dioica ), green tea leaves ( camellia sinensis ), and elderberry flowers ( sambucus nigra ). the chemical constituents of the extracts were identified using high-performance liquid chromatography and liquid chromatography plus mass spectrometry. six strains of as ...201728221885
genome-guided insights into the plant growth promotion capabilities of the physiologically versatile bacillus aryabhattai strain ab211.bacillus aryabhattai ab211 is a plant growth promoting, gram-positive firmicute, isolated from the rhizosphere of tea (camellia sinensis), one of the oldest perennial crops and a major non-alcoholic beverage widely consumed all over the world. the whole genome of b. aryabhattai ab211 was sequenced, annotated and evaluated with special focus on genomic elements related to plant microbe interaction. it's genome sequence reveals the presence of a 5,403,026 bp chromosome. a total of 5226 putative pr ...201728377746
tea polyphenols inhibit the growth and virulence properties of fusobacterium nucleatum.fusobacterium nucleatum plays a key role in creating the pathogenic subgingival biofilm that initiates destructive periodontitis. it is also a common resident of the human gastrointestinal tract and has been associated with inflammatory bowel disease. the aim of the present study was to investigate the effects of green and black tea extracts as well as two of their bioactive components, egcg and theaflavins, on the growth and virulence properties of f. nucleatum. the tea extracts and components ...201728322293
antimicrobial activity of aqueous extracts from four plants on bacterial isolates from periodontitis patients.four aqueous extracts of different plant organs are the following: artemisia herba-alba, opuntia ficus-indica, camellia sinensis and phlomis crinita were evaluated against two bacterial strains: porphyromonas gingivalis and prevotella intermedia, which are implicated in periodontal diseases. by using a disc method, these plant extracts demonstrated powerful bacterial activity against these gram-negative strains. the minimum inhibitory concentration values of the four plant extracts varied betwee ...201728386896
research on the effect of culture time on the kombucha tea beverage's antiradical capacity and sensory value.recent consumption trends shows high consumer acceptability and growing medicinal interest in the biological value of kombucha tea. this tea is a sweetened tea leaf brew fermented with a layer containing mainly acetic acid bacteria, yeast and lactic acid bacteria. the main antioxidants in tea leaves are polyphenols, the consumption of which is proven to be beneficial for human health, e.g. protecting from reactive oxygen species (ros). the aim of the present research was to evaluate antiradical ...201728071022
metal transport protein 8 in camellia sinensis confers superior manganese tolerance when expressed in yeast and arabidopsis thaliana.manganese (mn) is an important micronutrient element required for plant growth and development, playing catalytic roles in enzymes, membranes and dna replication. the tea plant (camellia sinensis) is able to accumulate high concentration of mn without showing signs of toxicity, but the molecular mechanisms underlying this remain largely unknown. in this study, the c. sinensis cultivar 'ljcy' had higher mn tolerance than cultivar 'ys', because chlorophyll content reduction was lower under the hig ...201728051151
tea (camellia sinensis) infusions ameliorate cancer in 4ti metastatic breast cancer model.tea (camellia sinensis) infusions are widely consumed beverages with numerous health benefits. however, physiological and molecular responses mediating these activities are poorly understood.201728388918
a simple, enzymatic biotransformation method using fresh green tea leaves efficiently generates theaflavin-containing fermentation water that has potent physiological functions in mice and humans.the polyphenolic compound theaflavin, the main red pigment in black tea, possesses many beneficial properties, such as fat-reducing and glucose-lowering capabilities. to produce theaflavin-containing fermentation water on a large scale, we have developed a simple, inexpensive, and selective enzymatic biotransformation method to obtain sufficient levels from fresh green tea leaves. subsequent administration of theaflavin-containing fermentation water to obese mice on a high-fat diet inhibited bod ...201728381812
effect of dental pigmentation intensity on the transenamel and transdentinal penetration of hydrogen peroxide.abastract this study aimed to evaluate the transenamel and transdentinal penetration of hydrogen peroxide (h202) applied to bovine teeth pigmented with black tea at different intensities. the following groups were formed dw: immersion in distilled water; bt100: immersion in an infusion of 1.6 g of black tea per 100 ml distilled water; bt10: immersion in an infusion of 1.6 g black tea per 10 ml distilled water. all groups were immersed for 6 days. to quantify the penetration of h202, the specimen ...201727652700
review on medicinal uses, pharmacological, phytochemistry and immunomodulatory activity of plants.since ancient times, plants have been an exemplary source of medicine. researchers have discovered some important compounds from plants. the present work constitutes a review of the medicinal plants whose immunomodulant activity has been proven. we performed pubmed, embase, google scholar searches for research papers of medicinal plants having immunomodulant activity. medicinal plants used by traditional physicians or reported as having immunomodulant activity include acacia concocinna, camellia ...201725280022
green tea proanthocyanidins cause impairment of hormone-regulated larval development and reproductive fitness via repression of juvenile hormone acid methyltransferase, insulin-like peptide and cytochrome p450 genes in anopheles gambiae sensu stricto.successful optimization of plant-derived compounds into control of nuisance insects would benefit from scientifically validated targets. however, the close association between the genotypic responses and physiological toxicity effects mediated by these compounds remains underexplored. in this study, we evaluated the sublethal dose effects of proanthocyanidins (pas) sourced from green tea (camellia sinensis) on life history traits of anopheles gambiae (sensu stricto) mosquitoes with an aim to unr ...201728301607
review of scientific evidence of medicinal convoy plants in traditional persian medicine.one concept used in traditional persian medicine (tpm) for multidrug therapy is that of the convoy drug (mobadregh). according to tpm texts, convoy drugs are substances (or drugs), which facilitate the access of drugs or foods to the whole body or to specific organs. this study reviewed some convoy drugs presented in tpm, their biological effects, and their probable interactions with main drugs, considering the increased absorption through inhibition of p-glycoprotein (p-gp) efflux function, bio ...201727041871
identification of a novel bzip transcription factor in camellia sinensis as a negative regulator of freezing tolerance in transgenic arabidopsis.basic region/leucine zipper (bzip) transcription factors play vital roles in the abiotic stress response of plants. however, little is known about the function of bzip genes in camellia sinensis .201728334275
metals content in herbal supplements.obesity has become an international epidemic. to evaluate the level of metals in extracts of plants prescribed as weight loss supplements, different brands containing camellia sinensis (l.) kuntze, citrus aurantium l., cordia ecalyculata vell, ilex paraguariensis a. st.-hil, cissus quadrangularis l., senna alexandrina mill were purchased in local market, hot acid digested, and analyzed while metal content by inductively coupled plasma optical emission spectrometry, icp-oes. quality assurance and ...201727344673
green synthesis of palladium nanoparticles mediated by black tea leaves (camellia sinensis) extract: catalytic activity in the reduction of 4-nitrophenol and suzuki-miyaura coupling reaction under ligand-free conditions.the present study was conducted to synthesize palladium nanoparticles (pd nps) through a facile and green route using non-toxic and renewable natural black tea leaves (camellia sinensis) extract, as the reducing and stabilizing agent. the as-prepared pd@b.tea nps catalyst was characterized by uv-vis spectroscopy, x-ray diffraction (xrd), fourier transformed infrared spectroscopy (ft-ir), field emission scanning electron microscopy (fe-sem), transmission electron microscopy (tem) and energy dispe ...201727665075
quality evaluation of green tea leaf cultured under artificial light condition using gas chromatography/mass spectrometry.for an experimental model to elucidate the relationship between light quality during plant culture conditions and plant quality of crops or vegetables, we cultured tea plants (camellia sinensis) and analyzed their leaves as tea material. first, metabolic profiling of teas from a tea contest in japan was performed with gas chromatography/mass spectrometry (gc/ms), and then a ranking predictive model was made which predicted tea rankings from their metabolite profile. additionally, the importance ...201727568369
a comparative analysis of chemical compositions in camellia sinensis var. puanensis kurihara, a novel chinese tea, by hplc and uflc-q-tof-ms/ms.camellia sinensis var. puanensis kurihara (puan tea) is a kind of ancient tea plant newly found in jiangxipo and the surrounding areas of puan county (guizhou, china). people there always believe that drinking puan tea is beneficial to the promotion of health and prevention of diseases. however, detailed information on its compositions has not been reported. therefore, in this study, the varieties and contents of purine alkaloids and polyphenols in puan tea were identified and determined by hplc ...201727596421
inhibition of pancreatic lipase and amylase by extracts of different spices and plants.the aim of this study is to search new anti-obesity and anti-diabetic agents from plant and spices crude extracts as alternative to synthetic drugs. the inhibitory effect of 72 extracts was evaluated, in vitro, on lipase and amylase activities. aqueous extracts of cinnamon and black tea exhibited an appreciable inhibitory effect on pancreatic amylase with ic50 values of 18 and 87 μg, respectively. aqueous extracts of cinnamon and mint showed strong inhibitory effects against pancreatic lipase wi ...201727706951
effect of oral theaflavin administration on body weight, fat, and muscle in healthy subjects: a randomized pilot study.theaflavins are reddish-colored polyphenols in black tea. to test the efficacy of theaflavin administration on body fat and muscle, we performed a randomized, double-blind, placebo-controlled study and investigated the effect of theaflavins administration on the body composition using of healthy subjects. in this study, 30 male and female japanese were enrolled and participants were randomly allocated to receive placebo, theaflavin (50 or 100 mg/day), or catechin (400 mg/ml) for 10 weeks. the ef ...201727756182
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