Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| pharmacokinetics of trimethoprim-sulfamethoxazole in children. | the present report extends experience with the use of trimethoprim-sulfamethoxazole (tmp-smx) in children aged 3 months to 10 years. the regimen was tmp (200 mg)--smx (1000 mg)/m-2d given in two equal doses. the drug was easily administered, well tolerated and efficacious in the treatment of a variety of infections in 12 children. a steady state had been achieved by the third dose of medication and accumulation of either component during days 1 through 4 did not occur. serum concentrations of tm ... | 1975 | 1093656 |
| use of antiserum agar for detection of haemophilus influenzae type b in the pharynx. | an antiserum agar medium was found to provide a rapid, sensitive, and highly specific method for pharyngeal culture and quantitation of hib. | 1975 | 1094393 |
| mapping and characterization of promoters in bacteriophages fd, f1 and m13. | 1975 | 1095754 | |
| recognition sequence of restriction endonuclease iii from hemophilus influenzae. | 1975 | 1095757 | |
| sensible prescribing. iii. acute otitis media and sore throat. | 1975 | 1096124 | |
| a freeze-squeeze method for recovering long dna from agarose gels. | 1975 | 1096670 | |
| analysis of the breaking sites in the physical degradation of dna. | the 3'-termini of procaryotic and eucaryotic dna fragments obtained by shearing, sonication and irradiation have been analyzed. analysis of the 3'-ends of dna fragments was done by 32-p-labeling with terminal transferase, hydrolysis of products by spleen dnaase and spleen exonuclease and separation of labeled 3'-terminal nucleotides on polyethyleneimine plates. in the case of sonication the deviation from dna base composition of 3'-terminal nucleotides is very close to random for escherichia col ... | 1975 | 1096947 |
| interactions in immunodeficiency. | 1975 | 1096992 | |
| comparative in vitro acitvity of chloramphenicol and thiamphenicol on common aerobic and anaerobic gram-negative bacilli(salmonella and shigella excluded). | the antibacterial activity of thiamphenicol was compared to that of chloramphenicol against 313 strains of gram-negative bacilli isolated from various clinical specimens. these two antiboitics were equally active against the 106 isolates of haemophilus mic equals 0.1 minus 1.56 mu g/ml) and against 40 strains of bacteroides fragilis (almost all strains being inhibited by 12.5 mug/ml of the two drugs). in contrast, when compared with chloramphenicol, 2-16 times as much of thiamphenicol was requir ... | 1975 | 1097209 |
| susceptibility of hemophilus influenzae, type b, to ampicillin at los angeles county/university of southern california medical center. a reappraisal after ten years. | 1975 | 1097620 | |
| analysis of bacteriophage mu and lambda-mu hybrid dnas by specific endonucleases. | 1975 | 1097703 | |
| mucolytic and antibiotic effect of a new compound in chronic bronchitis. | the purpose of the study was the objective evaluation of the mucolytic and antibiotic properties of fluimucil antibiotic, a molecular combination of acetylcysteine and thiamphenicol. the preparation was administered to 45 patients in the dose of 3 tablets daily each containing 500 mg of thiamphenical. statistical analysis of the data obtained showed mucolytic effects on the 4th to 5th day of treatment and marked antibiotic activity. the evaluation is positive particularly if the relatively low d ... | 1975 | 1098866 |
| mucormycosis in a transplant recipient. | mucormycosis classically occurs in patients who have uncontrolled diabetes who develop rhinocerebral disease. a fatal case of rhinocerebral infection caused by rhizopus arrhizus in a 53-year-old man who had received a renal homograft three years previously is reported. only five similar cases have been documented, all since 1970. although direct smears of the purulent nasal exudate revealed the presence of numerous gram-negative bacilli, later identified as haemophilus influenzae, the diagnosis ... | 1975 | 1099897 |
| mammalian dna endonuclease acting at apurinic sites: absence of associated exonuclease activity. | 1975 | 1100433 | |
| letter: epiglottitis, meningitis, and arthritis due to hemophilus influenzae type b presenting almost simultaneously in siblings. | 1975 | 1100798 | |
| acute epiglottitis; a clinical, bacteriological and serological study. | 25 patients, 15 children and 10 adults, with the clinical diagnosis of acute epiglottitis were studied. patients severely ill on admission, 13 children and 1 adult, were immediately treated with tracheotomy and antibiotics; the remaining patients with antibiotics only. haemophilus influenzae type b was the causative organism in all children and in 3 adults. one adult had a diplococcus pneumoniae infection. no pathogens were isolated from the 6 remaining patients. four of the children developed h ... | 1975 | 1101371 |
| [first description of haemophilus influenzae by richard pfeiffer]. | 1975 | 1102283 | |
| letter: chemical detection of beta-lactamase activity on haemophilus influenzae. | 1975 | 1102517 | |
| cleavage map of bacteriophage f1: location of the escherichia coli b-specific modification sites. | 1975 | 1102704 | |
| hybridization of labeled rna to dna in agarose gels. | specific dna restriction endonuclease fragments can be identified after electrophoresis in agarose gels by hybridization in the gel (in situ) to radioactive homologous rna. rna-dna hybrids are detected by autoradiography of the gel. comparison of band patterns of the autoradiogram and the ethidium bromide stained gel allows the identification of the dna fragment which is complementary to the rna probe. the technique is rapid, easy and inexpensive. it is sensitive enough to detect individual gene ... | 1975 | 1103090 |
| a transferable kanamycin resistance plasmid isolated from haemophilus influenzae. | kanamycin resistance was transferred by conjugation from a haemophilus influenzae strain into escherichia coli k12, and between e. coli k12 strains in subsequent transfers. covalently closed molecules of dna were isolated by sedimentation analysis of the dna of the resistant e. coli k12 strains. these facts support the hypothesis that kanamycin resistance is mediated by a transferable plasmid in this strain of h. influenzae. | 1975 | 1103677 |
| repair by genetic recombination in bacteria: overview. | dna molecules that have been damaged in both strands at the same level are not subject to repair by excision but instead can be repaired through recombination with homologous molecules. examples of two-strand damage include postreplication gaps opposite pyrimidine dimers, two-strand breaks produced by x-rays, and chemically induced interstrand cross-links. in ultraviolet-irradiated bacteria, the newly synthesized dna is of length equal to the interdimer spacing. with continued incubation, this l ... | 1975 | 1103833 |
| kinetics of photoreactivation. | this paper summerizes experimental work (most of which is published) in which light flashes were used for an analysis of photoenzymatic repair in vivo and in vitro. the method permits determination of the reaction rate constants for the formation, dark dissociation, and repair photolysis of enzyme-substrate complexes under various conditions, and estimation of the number of photoreactivating enzyme molecules present. investigation of these characteristics is basic for understanding of the overal ... | 1975 | 1103857 |
| classification of cephalosporins by their antibacterial activity and pharmacokinetic properties. | 1975 | 1104556 | |
| the immune response to acute otitis media in children. ii. serum and middle ear fluid antibody in otitis media due to haemophilus influenza. | the antibody response in serum and middle ear fluid was studied in 40 children less than two years of age who had otitis media due to haemophilus influenzae. specific antibody in serum was determined by either a bacteriocidal test or an indirect fluorescent antibody test, and in the middle ear fluid by the latter test. for both assays the infecting bacterium of the patient was used. half of the acute sera and three-fourths of the convalescent sera had antibody of at least one of the igg, igm, or ... | 1975 | 1104722 |
| phage lambda receptor chromosomes for dna fragments made with restriction endonuclease iii of haemophilus influenzae and restriction endonuclease i of escherichia coli. | 1975 | 1104875 | |
| [species and specificity of restriction endonucleases (author's transl)]. | 1975 | 1105682 | |
| the mechanism of replication of phix174 dna. xii. non-random location of gaps in nascent phix174 rf ii dna. | 1975 | 1107559 | |
| histone gene arrangement in the sea urchin, strongylocentrotus purpuratus. | the dna coding for histones from strongylocentrotus purpuratus, purified up to 100-fold with the use of hg+2-cs2-so4 and actinomycin-csc1 equilibrium density gradients, has been used to study the clustering of genes coding for different histones and the size of the repeating multigene cluster. when digested with ecori restriction endonuclease, the histone dna is identified in two classes of fragments with molecular weights of 1.15 x 106 and 2.8 x 106, whereas after treatment of the dna with hind ... | 1975 | 1108003 |
| letter: minocycline, amoxycillin and haemophilus influenzae. | 1975 | 1082999 | |
| acute epiglottitis. | 1975 | 1083515 | |
| simian virus 40 dna segment of the adenovirus 7-simian virus 40 hybrid, e46, and its transcription during permissive infection of monkey kidney cells. | nucleic acid hybridization methodology has been used to investigate the span of the simian virus 40 (sv40) dna segment in the adenovirus 7-sv40 hybrid, e46(+), and the extent of its transcription in lytically infected monkey kidney cells. the sv40 segment of e46(+) comprises approximately 62% of the sv40 genome; it originates in the proximal region of hin-g (the g fragment derived by cleavage of intact sv40 dna with haemophilus influenzae restriction endonuclease), extends sequentially through a ... | 1975 | 16789154 |
| traffic follows "streets" at gasthuisberg hospital. | 1975 | 235718 | |
| [bared back for the identification of scoliosis]. | 1975 | 274947 | |
| variations in x-ray exposures to patients. | x-ray exposures to patients were measured in 30 rooms in toronto hospitals. for a given procedure, the total exposure for a satisfactory examination differed from one room to another by as much as a factor of 30, skin exposures reaching 90 r and more for barium enemas and barium meals. the factors primarily responsible for these large differences in exposure were fluoroscopic exposure rate (0.65-12 r/min) and time 1.5-12 min), kvp and filtration (8:1), choice of screen-film combination (6:1) and ... | 1975 | 429443 |
| a modular computer system for radiologists. | a computer system was developed for two private radiology offices, consisting of six modular components, a history file, registration file, assisted reporting module, appointment management module, accounting module and statistical module. effectiveness and efficiency of patient care have been increased substantially. | 1975 | 429430 |
| circulating gastrin. | 1975 | 235880 | |
| assay of guanylyl cyclase catalytic activity. | 1975 | 1674565 | |
| [prevention of pulmonary complications in surgery of morbid obesity]. | 1975 | 1545629 | |
| letter: on the p/o index. | 1975 | 235846 | |
| [arteritis of takayasu, with aortic insufficiency and subclavian steal syndrome]. | 1975 | 235774 | |
| stability mapping along the dna double strand and its relation to the genetic map. | the distribution of the stability of the double helical structure along the whole dna of fdphage and its restriction fragments is calculated. in this calculation, poland's method, which has been established as a rigorous algorithm for taking the base sequence explicitly into consideration, is used. the molecular thermodynamic parameters in the calculation have been determined so as to best reproduce the melting profile of the dna and its fragments. the results, which are presented as melting map ... | 1975 | 429266 |
| motoneuron-disease-like disorder after ganglioside therapy. | 1975 | 1673540 | |
| sharing; 1:2:1. | 1975 | 246164 | |
| the assertive nurse practitioner. | 1975 | 246157 | |
| thermally induced chain exchange of frog alpha beta-tropomyosin. | the thermally induced unfolding of the alpha-helix of rana esculenta alpha alpha, alpha beta and beta beta tropomyosin and two tryptic fragments approximately corresponding to the n- and c-terminal halves of alpha beta have been investigated by use of optical rotation, circular dichroism and uv difference spectroscopy. reversible unfolding transitions of alpha alpha and beta beta occur around 49 degrees c and 32 degrees c, respectively. the helix unfolding of alpha beta shows two major transitio ... | 1975 | 1334716 |
| physiology of paraneurons. | an attempt is made in this review to elucidate the functional characteristics of paraneurons. the secretory functions of neuron, neurosecretory cell and paraneuron consist of three main phases: secretion, transmission and reversion. secretion can be divided into a steady state and an activated state. a paraneuron behaves characteristically in the active phase of secretion and in the phase of transmission. there are three main events in the activated phase of secretion ("stimulus-extrusion coupli ... | 1975 | 354576 |
| [celosomia]. | 1975 | 246077 | |
| levamisole immunotherapy of experimental transitional cell carcinoma. | levamisole, in doses comparable to those under clinical investigation, was shown to significantly (p less than 0.02) delay the onset of transplanted transitional cell carcinoma of c3h mice. the growth of transplanted tumors was inhibited and animal survival prolonged with levamisole treatment. further progress in the immunotherapy of transitional cell carcinoma may be aided by such models. | 1975 | 429122 |
| studies on the coupling rates in liquid-phase peptide synthesis using competition experiments. | competition experiments were carried out in order to determine relative reaction rates, vrel, for the peptide-forming step. using the liquid-phase method of peptide synthesis a model system was developed to investigate the influence of coupling method, amino component, derivatization and solvent upon vrel. according to a standard procedure, vrel for all 20 commonly occurring amino acids were established. a strong dependence of vrel upon steric effects of the coupling components was found. the da ... | 1975 | 429101 |
| [myelodysplastic syndromes in the aged]. | seventy-five cases of myelodysplastic syndromes (mds) in the aged (over 60 years) were analysed for hematological findings, immunological parameters and response to treatment in respect to prognostic significance. they were diagnosed according to the fab classification, but patients with hypoplastic marrow were included if myelodysplasia was evident. thirty-four percent of patients with primary acquired refractory anemia (para) or primary acquired sideroblastic anemia (pasa), and 36% of patients ... | 1975 | 2366331 |
| [obituary: charles gouygou (1919-1977)]. | 1975 | 354434 | |
| generalized pustular psoriasis with arthritis and pericarditis: case report. | 1975 | 475691 | |
| thrombolysis with tissue plasminogen activator in suspected acute myocardial infarction. the asset study. | intravenous rtpa (total dose, 100 mg over 3 h) was compared with placebo in a prospective, randomized, double-blind trial in 5,011 patients with suspected ami of less than 5 h duration. no ecg or enzymatic confirmation of the diagnosis was required for study entry. at 1 month 9.8% of patients given placebo had died compared with 7.2% of those who received rtpa (2.6% actual reduction, 26% relative reduction, with 95% confidence intervals of 11-39%). the majority of deaths occurred in patients who ... | 1975 | 2495910 |
| etiologic diagnosis of intrapleural empyema by counterimmunoelectrophoresis. | cultural methods failed to identify the infecting organism in 4 patients with intrapleural empyema. antimicrobial drugs had been administered to 3 of the patients before their admssion to the hospital. in each case, soluble polysaccharides believed to be those of pneumococcus or hemophilus were detected in the empyema fluid by counterimmunoelectrophoresis. these findings provided a rational basis for management of antimicrobial therapy for 3 of the patients and useful information on the origins ... | 1976 | 1083702 |
| spheroplasts of haemophilus influenzae induced by cell wall-active antibiotics and their effect upon the interpretation of susceptibility tests. | the interpretation of in vitro susceptibility tests of haemophilus influenzae performed by the agar or broth dilution methods with levinthal enrichment was found to be markedly influenced by the production of spheroplasts by this species. using an inoculum of 10(7) organisms/ml, this phenomenon was frequently evident macroscopically as a haziness on agar substrates and in broths containing cell wall-acting agents, such as ampicillin, cephalothin, and penicillin, but was not noted with chloramphe ... | 1976 | 1083711 |
| the management of hemophilus influenzae, type b, pericarditis. | the incidence of hemophilus influenzae, type b, infections in children has been increasing recently, so the number of cases of pericarditis is likely to rise also. we describe the clinical manifestations and treatment of h. influenzae, type b, pericarditis based on 4 patients and a review of the literature. the most common complication is cardiac tamponade, which requires drainage. all patients should be treated with antibiotics (chloramphenicol, ampicillin) and a drainage procedure. because of ... | 1976 | 1083717 |
| prognostic value of early features in rheumatoid disease. | extensive data on 102 patients who presented with rheumatoid disease within a year of onset were gathered by a prospective study to assess the prognostic value of early features. outcome was evaluated at a mean 4-5 years from onset on the basis of functional grade, extent of joint disease, early morning stiffness, and grip strength. twenty-six patients improved, 14 pursued a mild steady course, and 62 had a persistently severe or deteriorating condition. the features recorded at the first visit ... | 1976 | 1083760 |
| letter: hemophilus influenzae type b and epiglottitis. | 1976 | 1083901 | |
| location in bacteriophage lamdba dna of cleavage sites of the site-specific endonuclease from bacillus amyloliquefaciens h. | the sites in escherichia coli bacteriophage lambda dna cleaved by the site-specific endonuclease isolated from bacillus amyloliquefaciens h (bami) are found to be at 0.114, 0.466, 0.580, 0.713, and 0.861 lambda units. the sites were located by analysis of the products of digestion of lambda dna and lambda-ara transducing phage dna, and verified by double digestion with bami and ecori. | 1976 | 1083914 |
| prophage induction and inactivation by uv light. | analysis of the induction curves for uv light-irradiated haemophilus influenzae lysogens and the distribution of pyrimidine dimers in a repair-deficient lysogen suggests that one dimer per prophage-size segment of the host bacterial chromosome is necessary as a preinduction event. the close correlations obtained prompted a renewed consideration of the possibility that direct prophage induction occurs when one dimer is stabilized within the prophage genome. the host excision-repair system apparen ... | 1976 | 1083915 |
| topographical analysis of yeast ribosomal dna by cleavage with restriction endonucleases. | yeast ribosomal dna (rdna) was digested with the restriction enzymes hind iii, hind ii and a mixture of hind ii and hind iii. the cleavage products were analyzed by electrophoresis on 1.5% agarose gels. several distinct bands could be observed, which are derived from the redundant ribosomal transcription units. they are superimposed on a rather broad smear of background dna, representing the heterogenous 'spacer' sequences. from the restriction maps, together with data obtained by partial digest ... | 1976 | 1083938 |
| fragmentation of bacteriophage s13 replicative form dna by restriction endonucleases from hemophilus influenzae and hemophilus aegyptius. | 1976 | 1084079 | |
| relapse of hemophilus influenzae type b meningitis after combined antibiotic therapy: report of a case. | antibiotic therapy of bacterial meningitis is being reevaluated due to reports of ampicillin-resistant strains of hemophilus influenzae type b. the infant reported had a relapse of h. influenzae type b meningitis after an excellent clinical and bacteriologic response to an initial course of combined antibiotic therapy including chloramphenicol. this relapse is postulated to be due to localized cerebral vasculitis which was not treated for a sufficient period of time during the initial course of ... | 1976 | 1083007 |
| current status of ampicillin-resistant hemophilus influenzae type b. | 1976 | 1083008 | |
| [diagnosis and treatment of septic haemophilus influenzae arthritis and osteomyelitis in children]. | 1976 | 1083081 | |
| susceptibility of haemophilus influenzae isolates from blood and cerebrospinal fluid to ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole. | susceptibility to ampicillin and chloramphenicol in vitro has been determined for haemophilus influenzae strains isolated from blood and/or cerebrospinal fluid cultures of patients admitted to two atlanta hospitals from 1 january 1974 to 31 march 1975. since the appearance of ampicillin-resistant strains of this organism in early 1974, chloramphenicol has been used in these hospitals as initial therapy for severe infection due to h. influenzae. strains from five of 94 patients were resistant to ... | 1976 | 1083198 |
| mechanisms of ampicillin resistance in haemophilus influenzae type b. | the genetic mechanisms associated with ampicillin resistance in strains of haemophilus influenzae type b were investigated. in experiments concerned with transfer of total deoxyribonucleic acid in vitro, expression of resistance by wild-type strains occurred at a frequency of about 10%. the minimum inhibitory concentration of ampicillin for the transformed strains was similar to that of the resistant donor strains, and resistance in transformants was associated with acquisition of the ability to ... | 1976 | 1083199 |
| susceptibility of haemophilus influenza to ampicillin as determined by use of a modified, one-minute beta-lactamase test. | fifty-seven cultures of haemophilus influenzae were tested for production of beta-lactamase by use of a modified, 1-min test. only the 24 cultures that were ampicillin resistant, whether type b or not, yielded positive results for the enzyme; all ampicillin-susceptible isolates were uniformly negative. the beta-lactamase procedure is simple to perform and requires only commonly available reagents. | 1976 | 1083200 |
| spurious ampicillin resistance by testing haemophilus influenzae with agar containing supplement c. | ampicillin resistance (minimal inhibitory concentration >/=10 mug/ml) in the absence of beta-lactamase activity by haemophilus influenzae was noted in tests performed with mueller-hinton agar containing one lot of supplement c. all strains, except five with known resistance due to beta-lactamase activity, were inhibited by 0.6 mug or less of ampicillin per ml of chocolatized blood agar. | 1976 | 1083201 |
| susceptibility of ampicillin-resistant haemophilus influenzae to seven penicillins. | sixty-seven clinical isolates of haemophilus influenzae from various sections of the united states, england, and germany were tested for susceptibility to penicillin, ampicillin, amoxicillin, epicillin, carbenicillin, ticarcillin, and methicillin. fifty-three of the strains had previously been judged to be ampicillin resistant and 14 had been determined to be ampicillin susceptible. fifty-two of the 53 resistant strains produced beta-lactamase, but none of the susceptible strains produced it. on ... | 1976 | 1083202 |
| report of five children with hemophilus influenzae pneumonia. resistance to ampicillin must always be looked for. | five cases of hemophilus influenzae pneumonia were observed in a 13-month period at fairfax hospital, fairfax, va. more aggressive diagnostic procedures may be required in order to diagnose this disease with greater frequency. this has become especially important in view of the growing recovery of ampicillin-resistant h. influenzae strains. | 1976 | 1083325 |
| synthesis and release of polyribophosphate by haemophilus influenzae type b in vitro. | polyribophosphate, the capsular polysaccharide antigen of haemophilus influenzae type b, can be assayed in crude bacterial extracts by a combination of immunoprecipitation, hot-acid extraction, and colorimetry. in vitro, the antigen is synthesized during growth and, in well-buffered media, in early stationary phase as well. it is shed from the cell throughout the course of synthesis, and at 37 c almost all the extractable antigen has been released spontaneously within several hours after synthes ... | 1976 | 1083377 |
| counter immunoelectrophoresis in the diagnosis of septic arthritis caused by hemophilus influenzae. report of two cases. | 1976 | 1083389 | |
| host factors and antibody response haemophilus influenza type b meningitis and epiglottitis. | levels of antibody in serum after infection with haemophilus influenza type b or challenge with polysaccharide vaccine are highly variable. convalescent-phase serum antibody to the capsular polysaccharide of h. influenzae type b was measured in two groups of patients with pathophysiologically distinct diseases, meningitis and acute epiglottitis. antibody response after h. influenzae meningitis was subnormal. mean levels of antibody, the distribution of antibody levels by age, and erythrocyte and ... | 1976 | 1083399 |
| [phlegmon--a neglected sign of haemophilus influenzae septicemia?]. | 1976 | 1083467 | |
| comparative effectiveness of tetracycline, minocycline and doxycycline in treatment of acute-on-chronic bronchitis. a study based on sputum levels. | after the administration of minocycline, doxycyline and tetracycline in recommended therapeutic doses to 11, 10 and 12 patients respectively, sputum levels of these antibiotics were determined. only 20% of patients given doxcycline had a satisfactory sputum level and in the remainder levels were either low or absent. for patients receiving tetracycline and minocycline, 67% and 64% respectively had satisfactory sputum levels. patients selected for this study had a history of chronic bronchitis an ... | 1976 | 1083475 |
| antibiotics and invasive haemophilus influenzae. | 1976 | 1083486 | |
| quantitative antibiotic susceptibility testing: haemophilus influenzae type b. | twelve strains of haemophilus influenzae were tested for susceptibility to gentamicin, ampicillin, chloramphenicol and cephalothin using two methods, agar dilution and microdilution (broth). although inocula and incubation conditions were standardized, significant differences in the minimal inhibitory concentration (mic) were seen as a result of growth media. method dependent differences were also observed for some antibiotics. notwithstanding such variation, high level resistance of h. influenz ... | 1976 | 1108755 |
| phospholipids of haemophilus influenzae rd during exponential growth and following the development of competence for genetic transformation. | 1976 | 1082925 | |
| otitis media caused by non-typable, ampicillin-resistant strains of haemophilus influenzae. | strains of haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media. these children failed to improve with ampicillin therapy, and the resistant organisms persisted at the site of infection. patients infected with such ampicillin-resistant organisms require therapy with antimicrobial agents which are not susceptible to degradation by penicillin ... | 1976 | 1082931 |
| effects of haemophilus influenzae meningitis in infant rats on neuronal growth and synaptogenesis. | 1976 | 1082418 | |
| hemophilus influenzae bacteremia in children with sickle cell disease. | 1976 | 1082499 | |
| physical mapping of the hindiii, ecori, sal and sma restriction endonuclease cleavage fragments from bacteriophage t5 dna. | the dna of bacteriophage t5+ (molecular weight 76 x 10(6) dalton) has been dissected by various specific endonucleases. the restriction enzymes hindiii and ecori produce 16 and 7 fragments respectively, whereas sal and sma produce 4 fragments each. complete cleavage maps were established for the enzymes ecori, sal and sma and an almost complete map for hindiii. furthermore the location and size of the deletions st 20, st 14, b3, st 0 and b1 were determined. the correlation of the genetic and fun ... | 1976 | 1082539 |
| thymine hydroperoxide as a mediator in ionising radiation mutagenesis. | 1976 | 1082550 | |
| frequency of detection of hemophilus influenzae type b capsular polysaccharide in infants and children with pneumonia. | countercurrent immunoelectrophoresis was used to detect h. influenzae type b antigen in sera of 65 consecutive infants and children with clinical and radiographic evidence of pneumonia. antigenemia was observed in only one patient who also had h. influenzae type b bacteremia. blood cultures from four other children were positive for h. aphrophilus (one), streptococcus pneumoniae (two), and an alpha-hemolytic streptococcus (one). the frequency of pharyngeal colonization with h. influenzae type b ... | 1976 | 1082573 |
| ampicillin-resistant hemophilus sp. | 1976 | 1082793 | |
| treatment of spontaneous leukemia in akr mice with chemotherapy, immunotherapy, or interferon. | akr mice are genetically destined to develop gross (rna) virus-induced lymphatic leukemia. leukemic akr mice treated with combination vincristine, cyclophosphamide (cytoxan), and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea sustained a 180% increase of life-span. combination chemotherapy plus immunization with neuraminidase-treated allogeneic (gross virus-induced) g2g leukemic cells intradermally resulted in 35% of animals surviving beyond 150 days without evidence of the disease ... | 1976 | 1082796 |
| an enzyme system for replication of duplex circular dna: the replicative form of phage phi x174. | viral single strands (ss) are converted to the duplex from (rf) by a soluble enzyme fraction uninfected escherichia coli [schekman et al. (1975) j. biol. chem. 250, 5859-5865]. when reactions were supplemented with a soluble enzyme fraction from phi x174-infected cells, replication of phi x174 superhelical rf i dna was observed. the activity supplied by infected cells was absent in cells treated with chloramphenicol or in cells infected with a phi x174 phage mutant in cistron a (cis a). a host f ... | 1976 | 1064029 |
| [the possibility of a standardization of clinical trials concerning materials for root canal obturation]. | clinical trials constitute epidemiologic experiments, in comparable groups of human populations designed to assess the preventive of curative effects of agents or measures. international organizations (fdi, who, cioms, iso) have been instrumental in creating uniform methods, so that the findings from different sources can be validly compared. the need for a standardization of clinical trials in dentistry is particularly felt: - by the dental profession in order to make the choice of materials wi ... | 1976 | 1064975 |
| an adult with haemophilus meningitis: case report. | an adult woman was found to have acute pyogenic meningitis caused by haemophilus influenzae. recent reports questioning the rarity of this form of adult meningitis are briefly reviewed. | 1976 | 1066566 |
| evidence for glucocorticoid receptor in human leukocytes. | the glucocorticoid uptake in vitro by human periferal leukocytes was studied. the uptake showed 2 main components, one saturable and one non-saturable. the saturable component was compared with the uptake by the specific glucocorticoid receptor in rabbit granulocytes. the similarities with the rabbit receptor in structural specificity, time course of uptake at 37 degrees c, sensitivity to metabolic inhibition by pcms and the physiological concentration for half saturation indicate that the satur ... | 1976 | 1068630 |
| electrophoretic mobility of oral streptococci. | 1976 | 1068652 | |
| bacteriological findings in sinusitis (1963-1975). | two different studies were performed in order to determine the role of aerobic and anaerobic bacteria in sinusitis. aerobes: a retrospective study of 331 cases of all types of sinusitis (from 1963 till 1975) showed an increasing occurrence of haemophilus influenzae during the last three years. only in the acute sinusitis is streptococcus pneumoniae more frequently found than haemophilus influenzae, which exhibits the highest occurrence in chronic and undeterminable cases. we found cultures with ... | 1976 | 1070150 |
| a competitive protein-binding assay for 25-hydroxyvitamin d. | 1. we describe a modified competive protein-binding assay for 25-hydroxyvitamin d, which does not require the prior separation of vitamin d from 25-hydroxyvitamin d. 2. bovine albumin was used in the buffer, at a concentration of 1mg/ml, as a protein stabilizer and lipid solubilizer. bovine albumin from different manufactures produced very different non-specific binding of 25-(3h)hydroxycholecalciferol (ranging from 3.3 per cent to 58.9 per cent). 3. the mean concentration of 25-hydroxyvitamin d ... | 1976 | 1070425 |
| studies on the differential diagnosis of muscle glycogenoses: the hexose--monophosphates contents in muscles with lowered activity of phosphorylase. | 1976 | 1071088 | |
| cefuroxime - a new cephalosporin antibiotic. | cefuroxime is a new broad spectrum cephalosporin antibiotic for administration by injection. it is stable to most beta-lactamases. it is active against gram-positive organisms, including penicillinase-producing staphylococci, and has wide activity against gram-negative bacilli including enterobacter and many strains of indole-positive proteus spp. the substance is also highly active against haemophilus influenzae and neisseria gonorrhoeae. studies on human volunteers showed that it produced high ... | 1976 | 931792 |
| haemophilus influenzae meningitis. | 1976 | 931833 | |
| in vitro comparison of cefoxitin, cefamandole, cephalexin, and cephalothin. | the in vitro effect of cefoxitin, cefamandole, cephalexin, and cephalothin was tested against 645 strains of bacteria recently isolated from clinical sources. against gram-positive organisms cephalothin and cefamandole were the most effective, generally being three- to fourfold more active than cephalexin or cefoxitin. enterococci were not inhibited by less than 25 mug of any of the antibiotics per ml. against enterobacteriaceae, cefoxitin and cefamandole were the most active. an exception was t ... | 1976 | 938029 |
| activity of cefamandole and other cephalosporins against aerobic and anaerobic bacteria. | the activity of cefamandole was comparable to that of cephalothin, cefazolin, and cephaloridine against staphylococcus aureus, streptococcus pyogenes, and diplococcus pneumoniae. in contrast, cefamandole was considerably more active than cephalothin, cefazolin, or cephaloridine against gram-negative facultative bacilli, including haemophilus influenzae, the most striking disparities being noted with indole-positive proteus and enterobacter. bacteroides fragilis was more susceptible to cefoxitin ... | 1976 | 949182 |