Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| development of the brush border enzymes of guinea pig and rat enterocytes. | 1977 | 97934 | |
| [the value of the immunodiffusion test in the diagnosis of animal histoplasmosis]. | a serological study which involved the agar gel immunodiffusion test of 11316 animal serum samples (porcine, bovine, equine and ovine cattles) was made in the havana province in an attempt to detect precipitation bands for histoplasma capsulatum. 135 porcine serum samples and 4 bovine serum samples were positive. | 1977 | 98818 |
| electrophysiological investigation of cortico-hypothalamic relations in cats. | projections of different parts of the orbito-frontal cortex, the basal temporal cortex, and the hippocampus on hypothalamic nuclei were studied by recording focal responses in acute experiments on cats anesthetized with pentobarbital and chloralose. the proreal gyrus was shown to have local projections in the latero-dorsal zones of the preoptic region, in the postral parts of the medial forebrain bundle, and also in the region of the lateral and posterior hypothalamus with the mammillary bodies. ... | 1977 | 99685 |
| [studies on moraxella. ii. studies on the identification of moraxella by biochemical character (author's transl)]. | 1977 | 101604 | |
| lead poisoning in dogs. | 1977 | 97605 | |
| effect of auranofin, a new antiarthritic agent, on immune complex-induced release of lysosomal enzymes from human leukocytes. | auranofin, an oral chrysotherapeutic agent effective in the treatment of rheumatoid arthritis (ra), was found to be a potent, noncytotoxic inhibitor of igg-rf immune complex-induced lysosomal enzyme release (ler) from human leukocytes. at a concentration of 1 microg au/ml (5 microm), auranofin produced a marked reduction in beta-glucuronidase (100%), acid phosphatase (88%), and lysozyme (72%) release. in contrast, gold sodium thiosulfate (gst, an injectable gold compound) had no inhibitory activ ... | 1977 | 104928 |
| antigenicity of a spontaneous murine mammary adenocarcinoma during in vitro cultivation. | 1977 | 23597 | |
| evaluation of the effectiveness of receptor destroying enzyme preparations. | a procedure has been developed for testing receptor destroying enzyme (rde) preparations used to remove nonspecific inhibitors before carrying out haemagglutination inhibition tests with influenza virus. four criteria should be taken into account: (1) titre of rde, usually used to indicate the activity of the preparation; (2) neuraminidase activity of the preparation, determined biochemically, which partially corresponds to the rde titre; (3) direct demonstration of the complete removal of nonsp ... | 1977 | 23666 |
| light-activated calcium release from sonicated bovine retinal rod outer segment disks. | calcium trapped within sonicated and resealed bovine rod outer segment disks is released upon light exposure with a stoichiometry of 0.75 +/- 0.05 calcium for each rhodopsin bleached. the amount of calcium liberated is proportional to the amount of bleaching in the range of 20 to 100% bleaching and is relatively insensitive to the internal trapped calcium concentration. the results are obtained using a flow system in which the disk membrane vesicles are adsorbed on glass particle supported by a ... | 1977 | 14680 |
| possible subdivisions among alpha-adrenoreceptors in various isolated tissues. | the ratio (expressed in log10 units) of the equieffective concentrations of (+)- and (-)-noradrenaline has been measured in a variety of isolated tissues in the presence of cocaine (1 x 10(-5) m), tropolone (3 x 10(-5) m) and (+/-)-propranolol (5 x 10(-7) to 5 x 10(-5) m). the values obtained fall into 3 distinct and statistically different groups. firstly, a high group comprising (mean +/- s.e.) mouse vasdeferens (2-78 +/- 0-04), rabbit duodenum (2-91 +/- 0-07) and ileum (2-86 +/- 0-05). second ... | 1977 | 15074 |
| ph measurements in the vascular wall of dogs with electrically induced thrombosis of the femoral artery. | electrically induced thrombosis is often used for pathophysiologic and therapeutic experiments. the ph value of the vascular wall was measured to approach the features of this thrombosis. after inducing thrombosis by direct current, ph value of the intima of femoral artery was found decreased. the anode was inserted in the lumen. as to the behavior of the ph value, electric thrombosis and clinical thrombosis are similar. electric thrombosis therefore seems to be valuable for comparing investigat ... | 1977 | 15352 |
| studies on aronson's media with special reference to its utility in laboratory diagnosis of vibrio cholera. | 1977 | 24589 | |
| purification and properties of the methane mono-oxygenase enzyme system from methylosinus trichosporium ob3b. | 1. a three-component enzyme system that catalyses the oxidation of methane to methanol has been highly purified from methylosinus trichosporium. 2. the components are (i) a soluble co-binding cytochrome c, (ii) a copper-containing protein and (iii) a small protein; the mol. wts. are 13 000, 47 000 and 9400 respectively. the cytochrome component cannot be replaced by similar cytochrome purified from pseudomonas extorquens or by horse heart cytochrome c. 3. the stoicheiometry suggests a mono-oxyge ... | 1977 | 15544 |
| hormonal control of zinc uptake and binding in the rat dorsolateral prostate. | the zinc uptake in the dorsolateral prostate of rats was studied after different hormonal manipulations. orchiectomy reduced the uptake of 65zn. administration of estradiol benzoate to orchiectomized rats doubled the 65zn uptake, a phenomenon which was not observed in orchiectomized-adrenalectomized rats. adrenalectomy in orchiectomized rats had no effect on the concentration of radioactivity beyond the castration-induced decrease. a prolactin release inhibitor, 6-methyl-8-erogelenylacetamide, r ... | 1977 | 15955 |
| alpha-isopropylmalate synthase from alcaligenes eutrophus h 16 i. purification and general properties. | alpha-isopropylmalate (ipm) synthase, the first enzyme in the biosynthesis of l-leucine, was purified to a specific activity of 12 micronmole/min x mg protein from the valine-isoleucine double auxotrophic mutant a-81 of the hydrogen bacterium alcaligenes eutrophus h16. the activity in crude extracts of derepressed cells was 0.106 micronmoles of isopropylmalate formed per min and per mg protein. gel electrophoresis and regel electrophoresis of the isolated main band resulted in several distinct b ... | 1977 | 16576 |
| purification and properties of a membrane-associated, folate-binding protein from lactobacillus casei. | a folate-binding protein has been solubilized from lactobacillus casei by treatment of membrane preparations with triton x-100 in the presence of 3hfolate. the protein-folate complex was purified 100-fold and recovered in a 22% yield by adsorption and elution from microgranular silica (quso g-32), followed by passage through sephadex g-150. when subjected to sodium dodecyl sulfate/polyacrylamide gel electrophoresis, the purified preparations showed only a single, protein-staining band whose mole ... | 1977 | 16917 |
| adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of s49 mouse lymphoma cells. | a novel variant of the s49 mouse lymphoma has been selected from wild-type cells by growth in medium containing the beta-adrenergic agonist terbutaline and inhibitors of cyclic nucleotide phosphodiesterase. in contrast to the situation in the wild-type clone, synthesis of adenosine 3':5'-monophosphate (cyclic amp) is not stimulated by beta-adrenergic agonists or by prostaglandin e1 either in intact variant cells or in membrane preparations of such clones. however, basal and naf-stimulated activi ... | 1977 | 17119 |
| studies in acid-base balance. i. effect of alkali therapy in newborn dogs with mechanically fixed ventilation. | the effect of rapid or slow infusion of hypertonic sodium bicarbonate on acid-base balance and serum osmolality was studied in 36 acidotic newborn dogs. respiratory acidosis and hypoxia were produced by mechanically fixed hypoventilation. one group of animals breathed 100% o2 to prevent hypoxemia. rapid infusion of hco3- in acidotic and hypoxic animals resulted in only a transient (1 minute) and small (0.05 ph units) elevation of arterial ph followed by a continuous fall, resulting in a lower ph ... | 1977 | 17663 |
| cyclic guanosine-3',5'-monophosphate--mediator of the action of the hormaone erythropoietin. | 1977 | 18327 | |
| value of sputum culture in diagnosis of pneumococcal pneumonia. | in our laboratory, culture of sputum was extremely useful in diagnosing the etiology of pneumococcal pneumonia. of 31 consecutive patients with bacteremic pneumococcal pneumonia, 29 (94%) had streptococcus pneumoniae cultured from sputum. recovery of pneumococci in culture was enhanced by anaerobic incubation as well as by a plate bile test and an optochin disk on a primary blood agar plate. | 1977 | 18489 |
| pyruvate kinase from the moderate halophile, vibrio costicola. | 1977 | 19142 | |
| effect of prolonged gestation on placental and maternal liver enzyme activities in the rat. | 1977 | 19310 | |
| the identification of lipid acceptor and the biosynthesis of lipid-linked glucose in bacillus stearothermophilus. | 1977 | 20047 | |
| simple method for preparation of immune sera to envelope and nucleocapsid antigens of semliki forest virus. | immune sera to the envelope and nucleocapsid components of zaisan 260 and r 16225 strains of semliki forest virus (sfv) were prepared with the use of disrupted, partially purified virus. | 1977 | 20771 |
| effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen. | choleragen and its a protomer catalyzed the hydrolysis of nad to adp-ribose and nicotinamide. nadase activity was inhibited by gangliosides gm1 (galactosyl-n-acetylgalactosaminyl-n-acetylneuraminyl-galactosylglucosylceramide), gm2 (n-acetylgalactosaminyl-n-acetylneuraminyl-galactosylglucosylceramide), gm3 (n-acetylneuraminyl-galactosylglucosylceramide), and gd1a (n-acetylneuraminylgalactosyl-n-acetylgalactosaminyl-e1n-acetylneuraminyl-galactosylglucosylceramide). these gangliosides also increase ... | 1977 | 13371 |
| characterization of the thyrotropin receptor and its involvement in graves' disease. | 1977 | 69601 | |
| antigenic similarity of heat-labile enterotoxins from diverse strains of escherichia coli. | with use of the rabbit intestinal loop model, heat-labile enterotoxins from 21 escherichia coli strains isolated from a wide spectrum of patients with diarrheal diseases were all neutralized to high titer by two antisera prepared against enterotoxins of either e. coli or vibrio cholerae. these findings suggest marked immunological similarity among heat-labile enterotoxins from a heterogenous group of e. coli. | 1977 | 69630 |
| [possible errors in bacteriological diagnosis of cholera]. | 1977 | 69759 | |
| [dry media on yeast hydrolysates for growing vibrio cholerae]. | 1977 | 72881 | |
| antibiotic-induced colitis implication of a toxin neutralised by clostridium sordellii antitoxin. | a toxin(s) has been demonstrated in the stools of two patients with antibiotic-associated colitis. this toxin(s) was heat-labile, was rapidly lethal for hamsters, increased vascular permeability in rabbit skin, and was cytotoxic for cells in tissue-culture. it was neutralised by clostridium sordellii antitoxin but not by antitoxins prepared against other clostridia; escherichia coli, and vibrio cholerae toxins. these characteristics were identical to those of a toxin implicated in the aetiology ... | 1977 | 73011 |
| neutralization of salmonella toxin-induced elongation of chinese hamster ovary cells by cholera antitoxin. | a partially purified preparation of the delayed skin permeability factor from salmonella typhimurium caused chinese hamster ovary cells to elongate. the elongation effect and the skin test activity were blocked by monospecific rabbit antisera against cholera toxin and against the b fragment of cholera toxin, | 1977 | 67084 |
| [use of color differential medium and russell-i medium in the diagnosis of cholera vibrio]. | 1977 | 67254 | |
| specific inhibition of viral neuraminidases by an inhibitor, neuraminin, produced by streptomyces sp. | 1977 | 67704 | |
| complement-induced histamine release from human basophils. iii. effect of pharmacologic agents. | human serum activated with zymosan generates a factor (c5a) that releases histamine from autologous basophils. previously we have presented evidence that this mechanism for c5a-induced release differs from ige-mediated reactions. the effect of several pharmacologic agents known to alter ige-mediated release was studied to determine whether they have a similar action on serum-induced release. deuterium oxide (d2o), which enhances allergic release, inhibited in a concentration-dependent fashion th ... | 1977 | 65434 |
| [device for re-seeding in the tests for vibrioflora]. | 1977 | 75321 | |
| [use of the method of macrophage migration inhibition for titration of toxic activity in microbial fractions]. | 1977 | 75324 | |
| fine-structural localization of phosphatase activity on the plasma membrane of the rabbit sperm head. | 1977 | 137973 | |
| mechanism of action of choleragen. evidence for adp-ribosyltransferase activity with arginine as an acceptor. | choleragen catalyzed the hydrolysis of nad to adp-ribose and nicotinamide; nicotinamide production was dramatically increased by l-arginine methyl ester and to a lesser extent by d- or l-arginine, but not by other basic amino acids. guanidine was also effective. nicotinamide formation in the presence of l-arginine methyl ester was greatest under conditions previously shown to accelerate the hydrolysis of nad by choleragen (moss, j., manganiello, v. c., and vaughan, m. (1976) proc. natl. acad. sc ... | 1977 | 139409 |
| mechanical properties of cardiac muscle from spontaneously hypertensive rats: accentuated aftercontractions. | 1977 | 139613 | |
| morphine and 5-hydroxytryptamine interactions in rat hypothalamus and pineal body. | 1977 | 140058 | |
| recovery of preimplantation blastocysts in the squirrel monkey by a laparoscopic technique. | a laparoscopic uterine flushing technique has been developed for the recovery of preimplantation embryos from the squirrel monkey. fourteen adult female squirrel monkeys were induced to ovulate with 4 or 5 days' treatment with follicle-stimulating hormone (1 mg) followed by human chorionic gonadotropin (hcg) (500 iu). natural mating with a fertile male or artificial insemination was performed near the time of ovulation. thirty-six hours and eleven days after hcg administration, the females were ... | 1977 | 140077 |
| preparation of human immunoglobulin free of plasmin and anticomplement activities. | human igg separated by cohn fractionation showed variability in the content of aggregates, plasminogen and anticomplement activity. the plasminogen was removed or markedly reduced by affinity chromatography on sepharose-lysine. anticomplement activity was reduced by chromatography of cohn fraction ii on deae-cellulose. preparations of igg obtained by chromatography of intermediates from cohn fractionation (e.g. cohn fii + fiii or fii + fiii w) on deae-cellulose were devoid of aggregates, plasmin ... | 1977 | 140530 |
| differential effects of t-lymphocyte-derived soluble factor on virgin and primed b lymphocytes in vitro. | cell-free supernatants from mixed leukocyte cultures derived from histoincompatible mouse strains markedly enhanced the in vitro immune response to srbc by splenocytes from allogeneic mice. the supernatant factor or factors from allogeneic spleen cell cultures appeared to preferentially stimulate antigen-sensitized b lymphocytes, especially those involved in secondary igg antibody formation. furthermore, as shown in the present study, the enhancing supernatant factor or factors had no effect on ... | 1977 | 141139 |
| loss of striatal serotonin synaptic receptor binding induced by kainic acid lesions: correlations with huntington's disease. | 1977 | 142820 | |
| [electron-cytochemical distribution of acetylcholinesterase, monamine oxidase and mg2+-atpase in the human hypothalamus]. | the distribution of acetylcholinesterase, monoaminoxidase and atp-ase was studied in human hypothalamus by means of electron microscopy. the study demonstrated a possibility of differentiation of the hypothalamic neurons according to phases of neurosecretion. these data were achieved on the basis of electron cytochemistry in detecting atp-asa in the nuclei of neurons. comparing literary data concerning the nonmediator role of acetyl-choline and catecholeamines with personal studies, the authors ... | 1977 | 143176 |
| [enzymomorphology in cholerogenic intoxication in suckling rabbits]. | the cholerogenic effect produced in suckling rabbits by intraintestinal administration of a cholerogen was shown to be accompanied by the edema of villi, formation of lympho-histiocytic infiltrates in the stroma and bases of crypts, hemorrhages in the stroma of the villi and loss of individual enterocytes mostly on tops of the villi. in the large intestine, vacuolation and pyknosis of the epithelial nuclei and edema of the submucosa were observed. the intensity of the cholerogenic effect correla ... | 1977 | 143262 |
| iteraction of halothane with non-depolarizing neuromuscular blocking drugs in man [proceedings]. | 1977 | 143292 | |
| [antigenic relations between vibrio cholerae and aeromonas hydrophila]. | the antigenic relationships between vibrio cholerae and the oxidase-positive intestinal bacteria, agglutinated on slides by cholera antiserum, were investigated by the agglutination reaction. of the 478 oxidase-positive strains studied only strain 209 a, belonging to species aeromonas hydrophila was selected. evidence was found of common agglutinogenic fractions between vibrio cholerae and aeromonas hydrophila 209 a. attention is drawn to possible confusions in the preliminary stages of a labora ... | 1977 | 143704 |
| [demonstration of the variations in accessibility or reactivity of mitochondrial sh groups according to the energy status of the mitochondria]. | evidence for energy dependent variations of mitochondrial sh groups accessibility or reactivity was obtained using alkylating agents. these variations are thought to be consecutive to conformational changes affecting some proteins among them the phosphate carrier and the adenylic nucleotide translocator. | 1977 | 145307 |
| [t-cell subpopulations in mixed lymphocyte cultured. model of t-cell interactions]. | the present studies have shown that two subpopulations of thymus-dependent lymphocytes may act synergisticaly in the mixed lymphocyte reaction (mlr) in the mouse. one subpopulation was well represented in the young adult thymus and the other in lymph nodes. for optimum synergy, both populations must be allogeneic to the stimulator cells. pretreatment of either population with mitomycin-c abolished synergy. in a cinetic study lymph node cells were proliferating before thymus cells. a mixture of t ... | 1977 | 145401 |
| variation in potassium transport properties of mouse 3t3 cells as a result of subcultivation. | unindirectional potassium influx and the fraction of this influx sensitive to ouabain, an inhibitor of the (na + k) activated atpase, have been evaluated as a function of subcultivation of the 3t3 and sv40 transformed 3t3 cell. total and ouabain-sensitive k influx change little over approximately 50 passages of the transformed 3t3 cell. in contrast, these components of k influx increase nearly 5-fold over a similar number of passages of the 3t3 cell. during early passages total and ouabain-sens ... | 1977 | 145445 |
| developmental patterns of peripheral nerve, myoneural junction and muscle: a review. | 1977 | 148071 | |
| effect of propranolol on bile acid- and cholera enterotoxin-stimulated camp and secretion in rabbit intestine. | stimulation of net secretion by deoxycholic acid (dca) in the colon and by cholera enterotoxin (ce) in the jejunum is mediated by camp. propranolol (pr) inhibits adenylate cyclase (ac) activity and net secretion induced by bile acid in the colon. the aim of this study was to assess the organ specificity of dca and ce as well as the selectivity of pr inhibition. three colonic and three jejunal loops were prepared in each of 8 rabbits treated intravenously with pr, 4 mg per kg, 1/2 hr before loop ... | 1977 | 186351 |
| effect of indomethacin on cholera-induced fluid movement, unidirectional sodium fluxes, and intestinal camp. | cholera enterotoxin (ct) produces intestinal secretion associated with an elevation of intestinal cyclic amp (camp). indomethacin, a potent inhibitor of prostaglandin (pg) synthesis, decreases ct-induced secretion, although a role for pg in this process has not been demonstrated. the purpose of this study was to measure the effects of indomethacin on net fluid movement and unidirectional na fluxes in rabbit jejunal loops exposed to ct and to correlate these findings with intestinal camp levels. ... | 1977 | 186352 |
| modulation of in vitro erythropoiesis: enhancement of erythroid colony growth by cyclic nucleotides. | mammalian erythropoiesis, as assayed by erythroid colony formation in vitro, is enhanced by cyclic adenosine nucleotides and agents which are capable of raising intracellular cyclic amp (camp) levels. with canine marrow cells as target, this enhancement was shown to be specific for camp and its mono- and dibutyryl derivatives. adenosine and its derivatives, such as amp, adp and atp, and other cyclic nucleotides, such as cgmp, dibutyryl-cgmp, ccmp and cimp and sodium butyrate were inactive. the p ... | 1977 | 194698 |
| the glucagon receptor and its relationship to adenylate cyclase. | 1977 | 194799 | |
| [discreteness of satellite bacterial toxins]. | 1977 | 190828 | |
| ileal mucosal cyclic amp and cl secretion: serosal vs. mucosal addition of cholera toxin. | changes in ion transport and cyclic amp (camp) concentration produced by addition of cholera toxin to the serosal side of isolated rabbit ileal mucosa (cts) were compared to the changes produced by addition to the mucosal side (ctm). cts increased short-circuit current (scc) as did ctm but it did so more slowly. cts, unlike ctm, did not significantly decrease electrical conductance. inhibition of the scc response to theophylline, a measure of preexisting secretion, was almost complete 180 min a ... | 1977 | 190896 |
| the effect of attapulgite and charcoal on enterotoxicity of vibrio cholerae and escherichia coli enterotoxins in rabbits. | vibrio cholerae and certain strains of escherichia coli produce heat-labile enterotoxins which play a significant role in the pathogenesis of the intestinal disease. activated attapulgite, a heated magnesium aluminum silicate, was previously shown to prevent the toxic effects of endotoxin. the present study has revealed that this drug inhibits the toxic effects of cholera and e. coli enterotoxins in the intestinal loop of rabbits, when toxin and attapulgite are pre-incubated prior to injection. ... | 1977 | 202565 |
| structural changes of the tegumental membrane complex in relation to developmental stages of schistosoma mansoni (platyhelminthes: trematoda). | 1977 | 202726 | |
| interaction between cerulopasmin and sendai virus envelope components. note v. serological response in the rabbit to sendal virus and subviral fractions. | immunization of rabbits with sendai virus and subviral fractions induced the appearance in the serum of both hemagglutinin- and neuraminidase-inhibiting antibodies. the study of the correlation between antigen characteristics and the level and kinetics of the antibodies suggests that a single antigenic glycoprotein carries both hemagglutinin and neuraminidase activities. the level of serum antibodies depends both on the size and structure of the antigens and on their organization, and reflects t ... | 1977 | 203088 |
| calcium gradient dependent pyrophosphate formation by sarcoplasmic vesicles. | the vesicles of the sarcoplasmic membranes synthesize pyrophosphate from inorganic phosphate. pyrophosphate synthesis proceeds as long as a calcium gradient is maintained across the vesicular membranes. pyrophosphate synthesis is inhibited by low concentrations of nucleoside triphosphates. | 1977 | 203132 |
| multifunctionality of the enzyme in 2,3-bisphosphoglycerate metabolism of pig erythrocytes. | 1977 | 203152 | |
| cerebrospinal fluid production: stimulation by cholera toxin. | large increases in the production of cerebrospinal fluid have been observed after the intraventricular administration of cholera toxin. because cholera toxin stimulates adenylate cyclase, the data suggest that adenosine 3',5'-monophosphate plays a role in cerebrospinal fluid production. | 1977 | 193189 |
| regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors. | the effect of phenoxybenzamine (pba), desmethylimipramine (dmi), clonidine (clnd), sotalol (stl), and isoproterenol (ispr) on the release of endogenous norepinephrine (ne) from the heart on right cardioaccelerator nerve stimulation was studied in anesthetized dogs. under control conditions, the catecholamine levels in coronary sinus blood increased linearly with increasing frequencies of stimulation up to 10 hz and did not increase further at 30 hz. the release of ne was markedly enhanced after ... | 1977 | 193655 |
| fibrin adherent cho cell behavior in response to chelators and enterotoxin. | 1977 | 193707 | |
| glucose-induced proinsulin biosynthesis. role of islet cyclic amp. | 1977 | 193750 | |
| infectious murine type-c viruses released from human cancer cells transplated into nude mice. | type-c virus particles were revealed by electron microscope in 6 of 9 tumours of cultured and biopsied human cancers heterotransplanted into nude mice. some tumours in nude mice were explanted for in vitro cultivation. the virus particles were also found in the cultures derived from the virus-positive tumors. they were mostly found extracellularly, but the particles in budding process were also encountered frequently. cytological study and karyotype analysis of the cultured cells proved these vi ... | 1977 | 193756 |
| the storage lipids in tangier disease. a physical chemical study. | the physical states and phase behavior of the lipids of the spleen, liver, and splenic artery from a 38-yr-old man with tangier disease were studied. many intracellular lipid droplets in the smectic liquid crystalline state were identified by polarizing microscopy in macrophages in both the spleen and liver, but not in the splenic artery. the droplets within individual cells melted sharply over a narrow temperature range, indicating a uniform lipid composition of the droplets of each cell. howev ... | 1977 | 193870 |
| the role of cyclic nucleotides in lymphocyte activation and function. | 1977 | 194278 | |
| effects of yunnan bai yao on blood platelets: an ultrastructural study. | the effects of yunnan bai yao on blood platelets were studied at an ultrastructural level. this herbal drug is found to cause the release of platelet constituents which accounts for its hemostatic effects. the fine structural changes of platelets in response to this drug are also described. | 1977 | 204448 |
| the origin of acth cells in rat anterior pituitary. | 1977 | 211898 | |
| absence of the effect of ephedrine on levels of cyclic adenosine monophosphate in human lymphocytes. | concentrations of 10(-6) to 10(-3) m ephedrine did not increase cyclic adenosine monophosphate (camp) levels of normal human lymphocytes even in the presence of theophylline or cortisol, which enhance the response to isoproterenol or prostaglandin e1. preincubation for 2 hr with ephedrine did not reduce the subsequent effect of isoproterenol, although preincubation with isoproterenol itself did. therefore, ephedrine is not a direct beta-adrenergic agonist on human peripheral blood lymphocytes. | 1977 | 194936 |
| cyclic adenylic acid-dependent and -independent production of chloramphenicol acetyltransferase in escherichia coli carrying r plasmids. | a plasmid-specified, inducible, but cyclic adenylic acid (camp)-independent resistance to chloramphenicol (cm) is reported. the resistance level to cm was increased two- to fourfold by treatment with a small amount of cm for a short period in escherichia coli strains carrying the r plasmid pjy1, which was obtained from a clinical isolate of vibrio cholerae. though camp was required for production of cm acetyltransferase (catase) in camp-deficient mutants of e. coli carrying the r100 plasmid, the ... | 1977 | 195517 |
| increased de novo pyrimidine nucleotide synthesis in liver induced by ammonium ions in amounts surpassing the urea cycle capacity. | 1977 | 195808 | |
| relationship between the beta-adrenergic receptor and adenylate cyclase. | 1977 | 195960 | |
| postsynaptic induction of serotonin n-acetyltransferase activity and the control of cyclic nucleotide metabolism in organ cultures of the rat pineal. | 1977 | 196176 | |
| relationship between beta-adrenergic receptors and adenylate cyclase in hela cells. | 1977 | 196205 | |
| acute haemorrhagic conjunctivitis in hong kong 1971-1975. | acute haemorrhagic conjunctivitis occurred in epidemic in hong kong in 1971 and 1975 respectively. two picornaviruses, the enterovirus type 70 and an antigenic variant of coxsackie virus type a24, were isolated during the 1971 outbreak, while only the latter virus was detected in the 1975 outbreak. in 1972 and 1974, sporadic cases of conjunctivitis associated with enterovirus type 70 were observed. serological survey in late 1975 showed a high proportion of the population might still be suscepti ... | 1977 | 196351 |
| correlation between changes in intracellular level of cyclic amp, activation of cyclic amp-dependent protein kinase, and the morphology of chinese hamster ovary cells in culture. | 1977 | 196552 | |
| transformation of chicken embryo retinal melanoblasts by a temperature-sensitive mutant of rous sarcoma virus. | retinal melanoblasts were transformed by a temperature-sensitive mutant of rous sarcoma virus (ts-rsv). at the permissive temperature for transformation, the cells cease melanin synthesis, degrade their melanosomes and release much of their accumulated melanin into the medium. at the nonpermissive temperature, the cells assume an epithelioid morphology, actively synthesize melanin and become difficult to distinguish from normal uninfected control cultures. both the transformed phenotype and the ... | 1977 | 196765 |
| in vivo modulation of intracellular camp and cell growth of a lymphatic tumour in mice by cholera toxin. | 1977 | 196871 | |
| collagenase activity from cultured non-gravid rabbit uterus. | 1977 | 196959 | |
| effect of staphylococcus aureus delta toxin on chinese hamster ovary cell morphology and y-1 adrenal cell morphology and steroidogenesis. | since staphylococcus aureus delta toxin previously had been shown to increase the cyclic adenosine 3',5'-monophosphate (camp) content of guinea pig ileum, the effect of delta toxin on such camp-mediated responses as morphogenesis and steroidogenesis in cultured tissue cells was examined. in contrast to cholera toxin, delta toxin did not cause spindling of chinese hamster ovary cells. unlike adrenocorticotropin or cholera toxin, delta toxin was unable to cause rounding of y-1 adrenal cells or to ... | 1977 | 197006 |
| mechanisms of disease and immunity in cholera: a review. | the adenyl cyclase-activating enterotoxin of vibrio cholerae was shown to contain two types of subunit: six smaller units (l) that are responsible for the binding to cell membrane receptors and a larger unit (h) that mediates the toxic action. the receptor was identified as the ganglioside gm1 (galactosyl-n-acetylgalactosaminyl [sialosyl] lactosyl ceramide), and the results suggested that penetration of the toxin molecule into the membrane follows the rapid binding to gm1. the relationship of th ... | 1977 | 197173 |
| acth-dependent stimulation of a specific peptide in adrenocortical cells in culture. | 1977 | 197938 | |
| regulation of amylase release from dispersed pancreatic acinar cells. | 1. a study has been made of factors influencing release of amylase from dispersed pancreatic acinar cells. 2. in the basal, unstimulated, condition cells released 2-3% of the total amylase present in 30 min. 3. the rate of amylase release was stimulated 50-70% by c-terminal octapeptide of cholecystokinin (cck-op, maximally effective concentration, 3 x 10(-10) m); carbamylcholine (maximally effective concentration, 10(-5 m); secretin (maximally effective concentration greater than 10(-6) m); vaso ... | 1977 | 198531 |
| substrate positions and induced-fit in crystalline adenylate kinase. | 1977 | 198550 | |
| cell receptors for paramyxoviruses. | treatment of chick embryo fibroblasts, calf kidney and bhk cells for 30 minutes with the enzyme neuraminidase from vibrio cholerae causes an enhancement of the per cent of attached ndv virions. this enhancement does not depend on the multiplicity of infection. the quantity of spontaneously eluted and cellbound virus is two times greater than the quantity of the same virus derived from control cells. n-acetyl-neuramin lactose inhibits the effect of vibrio cholerae neuraminidase. after prolonged a ... | 1977 | 199141 |
| effects of neuraminidase on lectin binding by wild-type and ricin-resistant strains of hamster fibroblasts. | the nature of cell surface receptors for ricin on wild-type and ricin-resistant variants of baby hamster kidney fibroblasts has been studied. neuraminidase stimulated ricin binding threefold by wild-type cells, and increased their susceptibility to ricin toxicity as measured by inhibition of [3h]leucine uptake (ld30 fell from 5.0 to 0.5 microgram/ml). basal ricin binding by ricin-resistant variants (10-300% that of wild type) was also stimulated (2- to 17-fold) by neuraminidase in all seven clon ... | 1977 | 199243 |
| isolation and characterization of bound ion-sulfur proteins from bacterial photosynthetic membranes. i. ferredoxins iii and iv from rhodospirillum rubrum chromatophores. | 1977 | 199587 | |
| studies of isolated adult rat heart cells: the surface morphology and the influence of extracellular calcium ion concentration on cellular viability. | rat cardiac muscle was dissociated into single cells by a coronary perfusion technique with collagenase and hyaluronidase in a ca-free medium. retention of the cylindrical shape of isolated muscle cells could be achieved by regulation of [ca2+]0 and temperature. cells kept at 4 degrees c, and 0-01 mm cacl2 remained cylindrical for more than a week and contracted spontaneously upon warming at 37 degrees c. at [ca2+]0 between 0-1-2 mm and 37 degrees c, cells underwent contracture and rounded up. s ... | 1977 | 201046 |
| progesterone interaction with estrogen and antiestrogen in the rat uterus--receptor effects. | daily injections of estradiol or the antiestrogen tamoxifen initially stimulate uterine weight increase and progesterone receptor synthesis, though continued tamoxifen fails to maintain the increased weight. the stimulatory actions of both estradiol and tamoxifen are inhibited or reversed by a single injection of progesterone. it has been hypothesized that progesterone antagonizes estrogen action by reducing estrogen receptor levels, but in the present experiments neither cytoplasmic nor nuclear ... | 1977 | 201053 |
| [content of free amino acids in rabbit tissues as affected by adrenalectomy and administration of hydrocortisone and acth]. | adrenalectomy is accompanied by a decreased content of free amino acids in muscules and blood plasma by an increased content of certain amino acids in the liver. a single injection of hydrocortisone to adrenalectomized animals increases the content of amino acids in muscles and lowers their total content in the liver; a single injection of acth lowers the total content of amino acids in the liver and blood plasma "substitutive therapy" by hydrocortisone essentially increases the content of amino ... | 1977 | 201065 |
| viral hepatitis: enzyme assays and serologic procedures in the study of an epidemic. | an epidemic of viral hepatitis beginning in late 1975 in a residence for multiply handicapped children, recognized very early in its course, was investigated prospectively to permit comparison of enzymatic and serologic tests. thirty-three residents of the institution and 46 full- and part-time employees were studied by the immune adherence hemagglutination procedure for antibody (anti-hav) to hepatitis a virus (hav). of these, 31 residents and 37 staff members were susceptible at the beginning ... | 1977 | 201170 |
| plasma adrenocorticotropin levels in normal dogs. | plasma concentrations of adrenocorticotropin (acth; corticotropin) were measured in 31 normal dogs (house pets) at rest. the mean concentration was 45.77 pg/ml of blood, with individual values ranging from 17 to 98 pg/ml of blood. the measurement of this hormone secreted by the anterior lobe of the pituitary gland (adenohypophysis) may aid in the diagnosis of spontaneous canine adrenal cortical disorders, both primary and secondary. | 1977 | 201191 |
| cell culture propagation of porcine rotavirus (reovirus-like agent). | two isolates of porcine rotavirus (reovirus-like agent) were isolated and passaged in primary procine kidney cell cultures. viral infectivity for cells was monitored by immunofluorescence because viral cytopathic effect was moderate. successful passage of virus in cell culture required that viral suspensions obtained from infected cell cultures be treated with pancreatin prior to inoculation onto cell monolayers. porcine rotavirus passage in cell culture also was accomplished, using trypsin trea ... | 1977 | 201198 |
| an investigation of the homology of guanylate kinase isozymes in mammals and further evidence for multiple guk gene loci. | guanylate kinase in the red cells of 63 different mammalian species was studied by electrophoresis and multiple molecular forms of the enzyme were found in all species. two species were investigated in more detail. using molecular weight estimates as a criterion of homology, the fallow deer and the chinese hamster were found to have isozymes that corresponded to isozyme e, f, and g of man. variation in the guanylate kinase isozymes was detected in a small population of orangutans. results sugges ... | 1977 | 201245 |
| properties of a transposon conferring resistance to penicillins and streptomycin. | r938 carries a transposon (tabeta) of approximate molecular weight 9.5 megadaltons (mdal, 10(6) daltons). this contains genes for a beta lactamase of type tem-1 and for streptomycin phosphatransferase (spt). there is a ten-fold difference in the efficiency of transposition in different strains of e. coli k12. | 1977 | 201539 |
| cytomegalovirus infection in the neonate and its prevention. | about 0.5% of infants are infected in utero with cytomegalovirus (cmv). as many as 20% become mentally retarded and a further substantial proportion suffer lesser degrees of brain damage. the need for a vaccine is greater than in the case of rubella. a live, tissue culture-adapted strain of cmv has been shown to produce neutralizing antibody in volunteers without significant side effects or detectable virus excretion. the problems of developing such a vaccine for use in man, namely, attenuation, ... | 1977 | 201930 |