Publications

preventive activity of streptococcus viridans (ab1iii) against artificial colonization of pathogenic beta-hemolytic streptococci in rabbits.	a streptococcus viridans strain (ab1iii) with a strong interfering activity against pathogenic beta-hemolytic streptococci in vitro was stuided for its inhibiting activity in vivo. implantation of this strain into the oropharynx in rabbits provided them with complete resistance against artificially induced colonization of the upper respiratory tract by pathogenic beta-hemolytic streptococci.	1980	6772594
[physiological differentiation of streptococcus viridans].		1980	6788866
[internal carotid artery aneurism following peritonsillar abscess (author's transl)].	we report an unusual case of simultaneous occurrence of peritonsillar abscess due to streptococcus viridans with an aneurism of the internal carotid artery. inflammation caused by the abscess was so marked that its operative treatment unexpectedly uncovered the aneurism. we believe that the aneurism probably resulted from lymphatic spread of inflammation. although rarely occurring, such aneurisms are clinically very important: the danger of misinterpreting symptoms as those of a peritonsillar or ...	1980	6933145
[infective endocarditis: a complication of idiopathic hypertrophic subaortic stenosis (author's transl)].	the idiopathic hypertrophic subaortic stenosis (ihss) is thought to be infrequently complicated by infective endocarditis. because ihss is a disorder of the myocardium and not endocardium is not generally considered to have increased risk of infective endocarditis. some authors found, however, that approximately 5% of patients with ihss develop bacterial endocarditis, because hemodynamically ihss is like to valvular diseases. therefore the incidence of endocarditis in ihss is the same of valvula ...	1980	7193153
[treatment of infection in the patients wih hematopoietic malignancy with ceftezole (falomesin) (author's transl)].	ceftezole (ctz) was administered to 20 patients with hematopoietic malignancy complicated with infections. these patients consisted of 7 cases of aml, 2 all, 2 ammol, 1 apl, 1 blast crisis of cml, 2 hd, and 5 nhl. in 13 cases, sites of infection were determined and causative organisms were identified. in other 7 cases, sites of infection or causative organisms were unknown. in the former 13 cases, pneumonia was demonstrated in 6 patients, tonsillitis in 4 patients, pyelonephritis in 2 patients a ...	1980	7218516
mammalian bite wounds.	clinical data were collected prospectively from a series of 160 patients presenting with mammalian bite wounds. anaerobic and aerobic cultures were prepared from sterile swabs placed in 65 bite wounds prior to cleansing. infection was noted in 11 of 22 cat bites, six of 37 human bites, three of 80 dog bites, and in none of the 21 bites caused by other mammals. pasteurella multocida was recovered from six infected cat and dog bites, all of which developed infection within 24 hours of injury. stap ...	1980	7356213
the demonstration of vegetations by echocardiography in bacterial endocarditis. an indication for early surgical intervention.	the visualization of vegetations by m-mode echocardiography in patients with infective endocarditis has been suggested to imply a poor prognosis regarding the development of major systemic emboli, congestive heart failure and the need for early surgical intervention. the question of using the finding of vegetations by echocardiography as an indication for surgery is controversial. to answer this question, 30 patients with the clinical diagnosis of endocarditis were studied by echocardiography. i ...	1980	7386509
purification and properties of two neuraminidases from streptococcus viridans ii.		1980	7409155
dog bite wounds and infection: a prospective clinical study.	we prospectively studied 26 patients with 27 dog bite wounds who sought medical attention in the emergency department. two distinct populations were found (fishers exact test, p less than or equal to 0.001): 1) those who presented 8 hr to 12 hr post-injury were concerned about rabies or tetanus or surgical wound repair; and 2) those who presented more than 12 hr post-injury were concerned with infection. there was no difference (p > 0.05) in the bacteriology of the two groups. of all wounds, 74% ...	1980	7425403
virulent streptococcus viridans bacterial endocarditis.	a particularly virulent form of bacterial endocarditis due to streptococcus viridans is described in selected patients. the diagnosis of purulent pericarditis and myocardial abscess is delineated. in addition, emphasis is placed on early surgical intervention in the appropriate management of these potentially lethal complications.	1981	7468419
[a case of mastitis caused by streptococcus viridans biotype iv (author's transl)].	a case of clinical bovine mastitis caused by infection with streptococcus viridans, biotype iv was reported. of a dairy herd of twenty-three cows, three animals were severely affected with clinical mastitis of at least two quarters in each cow. streptococcus viridans, biotype iv, in pure culture was subsequently isolated on two occasions from eight quarters of these cows. following experimental infection with the isolated streptococcus viridans in a normal lactating cow, mastitis appeared with s ...	1981	7222006
pathological study of infective endocarditis on hancock porcine bioprostheses.	a pathological study has been performed on 10 infected hancock bioprostheses removed from nine patients who died of prosthetic endocarditis. the devices had been in place from 2 to 87 months (average 37.5), the interval between operation and onset of infection averaging 30 months. the offending organisms were gram negative bacteria in three patients (klebsiella pneumoniae, enterobacter cloacae, and serratia marcescens), gram positive bacteria in two (staphylococcus aureus and streptococcus virid ...	1981	7230861
treatment of severe lower respiratory tract infections with ceftriaxone (ro 13-9904). a pilot study.	two pilot comparative trials in 29 patients suffering from severe lower respiratory tract infections are described. 15 patients received 7-10.5 g ceftriaxone as a total dose and 14 received 28 g amoxicillin, both antibiotics being given by intravenous route during 1 week. the local and systemic tolerance of the drugs were satisfactory; no adverse reactions or relevant laboratory changes were noticed. the clinical response was favourable in all patients. the mot relevant pathogens found in the sp ...	1981	7249798
bacterial endocarditis. a retrospective study of cases admitted to the university of alabama hospitals from 1969 to 1979.	a retrospective study was conducted at the university of alabama in birmingham medical center on patients diagnosed as having be from the years 1969 to 1979, with emphasis on dental involvement. a major finding of this report revealed that 16 percent of the cases of be had a history of recent dental care or pathology. other results of this investigation included the following: (1) streptococcus viridans was the predominant microorganism associated with be; (2) the mortality rate relative to pred ...	1981	6946359
microbial flora of the lower genital tract of women in labour in zaria, nigeria.	nine genera of microbes isolated from the lower genital tract of 187 women in labour in zaria have been identified. the work was undertaken to establish the nature of microorganisms in the lower genital tract of women in labour as a basis for further study. the isolates in order of prevalence were: candida albicans (20.9%), klebsiella sp (15.0%), escherichia coli (9.1%), streptococcus faecalis (6.4%), haemolytic streptococci (other than streptococcus pyogenes (2.7%), streptococcus viridans (2.1% ...	1981	7007447
premature labor. ii. bacterial sources of phospholipase.	human term labor is thought to be initiated by amniotic and chorionic phospholipase a2, an enzyme that liberates arachidonic acid esters from the phospholipids of these membranes, leading to the synthesis of prostaglandins by the placental membranes. the striking association of premature labor with intrauterine infection or contamination, urinary tract infection, and early neonatal sepsis led us to study the microorganisms present in these infections for phospholipase a2 activity. activity was f ...	1981	7017516
bacteriologic investigation and histologic observations of variably acid-fast bacteria in three cases of cutaneous kaposi's sarcoma.	skin biopsy specimens from 3 consecutive patients with lesions of kaposi's sarcoma limited to the skin were cultured for bacteria, and also examined histopathologically for the presence of acid-fast wall deficient (cwd) bacteria. corynebacterium sp and propionibacterium acnes were isolated from two repeated cultures from the first case. both staphylococcus epidermidis and streptococcus viridans were isolated from the second case. bacteriologic culture of the third case was negative. utilizing th ...	1981	6169593
infective endocarditis in thirteen children: a retrospective study (1974-1981).	thirteen children (11 african, two indian) with infective endocarditis are described. rheumatic heart disease was present in nine of the children and was therefore a major determinant of infective endocarditis whereas a congenital cardiac abnormality (fallot's tetralogy) was detected in only one child. staphylococcus aureus was the commonest infecting organism, being found in five children, and streptococcus viridans was isolated in one. fever, murmurs and anaemia were the most frequent clinical ...	1982	6185079
characteristic and kinetics of the in vitro interfering activity of the streptococcus viridans ab1iii strain.		1982	7047458
acute bacterial endocarditis with postpartum aortic valve replacement.	a case of acute bacterial endocarditis with aortic valve abscess, aortic insufficiency, and congestive heart failure at 32 weeks' gestation is described. prompt valve replacement is indicated due to the risks of embolism to the coronary arteries and brain, and to the high mortality of such patients with medical management only. the infant was delivered prematurely to avoid the intraoperative risks to the fetus of cardiac surgery. general rather than regional anesthesia was chosen because venous ...	1982	7078843
in vitro activity of u-57930e, a new clindamycin analog, against aerobic gram-positive bacteria.	the in vitro activity of u-57930e, a new clindamycin analog, against aerobic gram-positive cocci was studied by microdilution broth susceptibility tests and compared with the activities of clindamycin, vancomycin, oxacillin, and ampicillin. u-57930e inhibited methicillin-susceptible staphylococcus aureus, streptococcus pyogenes, streptococcus agalactiae, and streptococcus viridans at concentrations of less than or equal to 1 microgram/ml. this degree of activity was generally slightly less than ...	1982	7114838
bacterial endophthalmitis following cutting of sutures after cataract surgery.	bacterial endophthalmitis developed in four patients after cataract surgery sutures were cut. wound dehiscence was present in three cases, but in one the wound remained intact. vitreous cultures identified streptococcus viridans in two cases and staphylococcus aureus and st. epidermidis in one case each. antibiotic therapy was administered by intraocular, periocular, topical and systemic routes and three patients underwent vitrectomy. visual function recovered to 20/50 in two cases and to 20/100 ...	1982	7137278
ascending intrauterine infections in rhesus monkeys.	seventeen cases of abortions and stillbirths from a harem breeding colony of rhesus monkeys (macaca mulatta) were studied to determine the role of aerobic bacteria in their etiology. using histopathologic criteria correlated with bacterial cultures, the cause in 11 of 17 cases was found to be ascending infection with normal vaginal flora, most commonly gram-positive cocci, especially an alpha-hemolytic streptococcus (streptococcus viridans). actively breeding animals in the colony were screened ...	1982	7174462
[treatment of peritonitis in continuous ambulatory peritoneal dialysis ].	thirty patients were treated with continuous ambulatory peritoneal dialysis during 313 patients months. 26 episodes of peritonitis defined by a cloudy dialysate with more than 100 cells/mm1 and more than 50 p. cent of polynuclear were observed. the organisms initially responsible were gram-positive in 11 cases (6 staphylococcus aureus, 1 staphylococcus albus, 4 streptococcus viridans), a gram negative in 3 cases (1 klebsiella, 1 serratio, one unidentified), a candida in 2 cases. in 10 cases, the ...	1982	6750528
balloon embolization of a mycotic pulmonary artery aneurysm.	a patient presented to the hospital with mild hemoptysis of 1 day's duration and an infiltrate on chest roentgenogram. shortly after admission, she developed shock, massive hemoptysis, and a bloody pleural effusion that yielded streptococcus viridans. pulmonary arteriography revealed a peripheral pulmonary artery aneurysm, which was embolized with a detachable silicone balloon, resulting in immediate cessation of hemoptysis. an acute pneumonia associated with moderate to massive hemoptysis raise ...	1982	6897502
clinical and echocardiographic features of pulmonary valve endocarditis.	we studied the clinical and echocardiographic features of eight patients with infective pulmonary valve endocarditis. in two patients, the vegetation was limited to the pulmonary valve; in the six other patients, infective lesions were also present on the mitral or aortic valves. none of the patients were addicted to narcotics. seven of the eight patients had underlying congenital heart disease. in six patients the organism responsible for the infective endocarditis was streptococcus viridans. t ...	1983	6847798
a controlled trial of cefaclor versus amoxicillin for treatment of acute otitis media in early infancy.	optimal antimicrobial therapy of acute otitis media with effusion in early infancy is controversial. we studied the efficacy of cefaclor and amoxicillin in the treatment of 40 nonconsecutive infants less than 3 months of age in a double blind comparative trial. infants were randomly assigned to receive either oral amoxicillin or cefaclor in a dosage of 40 mg/kg/day divided into 3 doses for 10 days. clinical responses and adverse drug effects were evaluated at 48 to 72 hours, 5 to 7 days, 2 weeks ...	1983	6340079
the teeth and infective endocarditis.	during 1981 and 1982 544 cases of infective endocarditis were investigated retrospectively by means of a questionnaire. only 13.7% had undergone any dental procedure within three months of the onset of the illness, and in 42.5% there was no known cardiac abnormality before the onset of the disease. furthermore, the number of cases occurring annually was about the same as or more than it was before the introduction of penicillin. the mouth and nasopharynx were the most likely sources of the commo ...	1983	6360190
clinical and microbiologic aspects of serious infections caused by staphylococcus epidermidis.	10 patients with serious infections caused by staphylococcus epidermidis (8 cases of endocarditis in non-prosthetic valves, 1 was complicated by osteomyelitis, 1 case of osteomyelitis, and 1 case of septicemia) are described. clinical and microbiologic features were evaluated including antibiotic sensitivity and synergy studies, phage typing and biotyping. endocarditis tended to affect the elderly population and the clinical manifestations were quite similar to those caused by streptococcus viri ...	1983	6361977
pelvic abscess associated with a lippes loop. an unusual case.	an unusual case occurred of lippes-loop-associated pelvic abscess, characterized by a relatively mild clinical course and an unusual localization in the pelvis. this case emphasizes the importance of considering the association between intrauterine devices and pelvic abscess.	1983	6631839
clinical comparison of glucose broth with nutrient broth blood cultures for the detection of "streptococcus viridans" bacteraemia.	viridans streptococci were isolated from the blood stream of half of 50 patients undergoing dental extractions approx. 2 min before blood culture. glucose and nutrient broths were tested in parallel. there was no significant difference between the isolation rates of streptococci by the two methods after incubation for 7 days, nor did the addition of glucose 0.1% to nutrient broth significantly increase the speed of detection of streptococci; the isolation rates of streptococci during the first 4 ...	1983	6644789
[streptococcus viridans pneumonia].		1983	6656363
aortic and mitral valve replacement for bacterial endocarditis in pregnancy. a case report.	a 24-weeks pregnant woman presented with bacterial endocarditis due to streptococcus viridans and severe aortic and mitral valve incompetence. progressive deterioration in haemodynamic function and the presence of systemic emboli necessitated the urgent performance of aortic and mitral valve replacement; both the patient and the fetus survived. double valve replacement for infective endocarditis in pregnancy has not previously been reported.	1983	6665656
[differentiation of pneumococcus and streptococcus viridans in a mixed sputum culture].		1983	6187989
detection and partial characterization of antibacterial factor(s) in alveolar lining material of rats.	intracellular killing of staphylococcus aureus by alveolar macrophages is known to be enhanced by exposure to alveolar lining material. because this material may have a role in pulmonary host defenses, we have studied its effect on pneumococci and other nonstaphylococcal organisms. alveolar lining material from rats caused rapid killing and lysis of pneumococci. the antipneumococcal activity was localized to the surfactant-containing fraction of the fluid and was not affected by trypsin. phospho ...	1983	6129262
[polymicrobial endocarditis caused by haemophilus influenzae and streptococcus viridans. a chance association?].		1984	6332957
a comparative study of infective endocarditis.	a survey of hospitalizations at the chaim sheba medical center, covering two nonconsecutive decades (1951-60 and 1970-79), included 213 patients (228 episodes) with infective endocarditis. the increase in the age of patients and in the frequency of atherosclerotic heart disease, as well as the introduction of techniques such as heart catheterization and open-heart surgery, are responsible for the differences in clinical course, microbiology and therapy. despite the changed pattern, rheumatic hea ...	1984	6469557
[sternal arthritis caused by streptococcus viridans in a heroin addict].		1984	6513662
bacterial endocarditis presenting as acute vertebral osteomyelitis: 14 cases.	association between bacterial endocarditis (be) and vertebral osteomyelitis (vo) has infrequently been noted. in a retrospective analysis of be (280 cases) and vo (150 cases) 14 cases were found to have this association. there were 12 males and 2 females, ages ranging from 39 to 72 years, mean age 56.6. blood cultures were positive for streptococcus viridans (6 cases). str. faecalis (4 cases), staphylococcus (2 cases), gram negative bacteria (1 case). organism was not isolated in one case. fever ...	1984	6519073
prosthetic valve endocarditis in pregnancy.	a case of prosthetic valve endocarditis is described, caused by streptococcus viridans in the third trimester of pregnancy. during her illness, the patient gave birth to a normal baby in an uncomplicated vaginal delivery. she had recurrent post-partum vaginal bleeding. aspects relevant to the management of the case are discussed.	1984	6524308
a potential infection hazard associated with the use of disposable saline vials.	nosocomial respiratory tract infections have occasionally been associated with contaminated respiratory therapy devices and techniques. in the past two years, our hospital purchased disposable saline squeeze vials for use during suctioning of intubated patients. these vials have a cap which must be flipped or twisted-off by the user before the contents can be instilled into the patient's respiratory tract. we observed use of this item in our intensive care units (icu) and studied the potential f ...	1984	6562088
hospital personnel with penicillin-resistant streptococcus viridans. a case for special consideration in the prevention of bacterial endocarditis.	penicillin is the drug of choice for the prevention of bacterial endocarditis (be) resulting from dental treatment. the susceptibility of streptococcus viridans to this antimicrobial agent was studied. a representative sample of hospital personnel (n = 76) was compared to a control group of seventy-six subjects who were not associated with the hospital. twenty-four of the hospital personnel worked in wards that consume 0.13 to 1.64 (mean +/- sd = 0.88 +/- 0.64) gm penicillin per day per position ...	1984	6593664
[anaerobic microbes in perimandibular inflammation].	studies conducted in 16 patients with perimandibular inflammation included bacteriological examinations and tests of the resistance of the bacterial flora to 6 antibiotics:davercin, erythromycine, penicillin, ampicillin, tetracycline and chloramphenicol. a total of 73 strains (47 anaerobic and 26 aerobic) were isolated, including 47 gram - and 26 gram's strain +. anaerobic gram - ve bacteria appear to be the principal cause of perimandibular inflammatory lesions, streptococcus viridans being ide ...	1984	6596693
endophthalmitis and pars plana vitrectomy.	a review of all cases of suspected endophthalmitis following cataract extraction seen at one referral hospital between 1979 and 1983 was conducted. of the 13 cases, 7 were proven by culture to be bacterial endophthalmitis when organisms were grown from aspirates of the aqueous, the vitreous or both. antibiotic therapy was administered by intravitreal, periocular, topical and systemic routes. in some cases vitrectomy was performed immediately after the diagnostic aspiration or within 24 hours. po ...	1984	6608975
aortic valve endocarditis complicated by complete heart block.	a 34-year-old man with severe aortic incompetence caused by streptococcus viridans developed severe central chest pain followed by complete heart block, multifocal ventricular extrasystoles, lengthening of the qtc and signs of cerebral emboli and pulmonary oedema. early antibiotic therapy along with pacing, non-invasive investigations coupled with early surgery contributed significantly to the patient's survival.	1984	6693217
glomerulonephritis in bacterial endocarditis.	for a modern assessment of the clinical and morphologic features of glomerulonephritis accompanying bacterial endocarditis, postmortem and renal biopsy files were reviewed for the years 1965 to 1979, a period of changing epidemiology, etiology, and therapeutic regimens in infective endocarditis. the incidence of glomerulonephritis in 107 patients examined at postmortem was 22.4%; focal glomerulonephritis was present in 8.4%, diffuse glomerulonephritis in 14%. glomerulonephritis occurred as frequ ...	1984	6702824
[streptococcus viridans pneumonias].		1984	6738207
clinical and echocardiographic correlations in right heart endocarditis.	the echocardiographic findings were correlated with the clinical findings and outcome in 23 patients with tricuspid valve or pulmonary valve endocarditis. there were 15 males and 8 females with a mean age of 33.1 +/- 8.4 years. eighteen patients had tricuspid valve endocarditis, 1 patient had pulmonary valve endocarditis, 3 patients had concomitant mitral valve and tricuspid valve endocarditis, and 1 patient had tricuspid valve and pulmonary valve endocarditis. twenty of the 23 (87%) patients ha ...	1984	6746135
effect of volume of blood cultured on detection of streptococcus viridans bacteraemia.	fifty eight patients undergoing dental extraction each had 45 ml blood collected. this was divided into 30 ml and 15 ml blood samples for culture. the 30 ml sample was inoculated into 120 ml nutrient broth with 0.05% liquoid and the 15 ml sample into 60 ml of identical broth so that the final dilution of blood in broth was always 1/5. bacteraemia due to viridans streptococci was found in 27 and 15 patients by culturing the 30 ml and 15 ml blood samples respectively. only one further case of stre ...	1984	6373833
glomerulonephritis in bacterial endocarditis.	the introduction of antibiotic therapy and changing epidemiologic patterns have altered the nature of glomerulonephritis as it occurs during the course of bacterial endocarditis. observations made predominantly in the pre-antibiotic era suggested that infections with less virulent organisms, by virtue of their indolent subacute course, favored an antibody response predisposing to immune complex glomerulonephritis. although antibiotic prophylaxis and therapy have reduced the incidence of both str ...	1984	6380288
pathogenicity of alpha hemolytic streptococci in the neonate.	alpha hemolytic streptococcus viridans (ahsv) was found to be the predominant pathogen in neonatal septicemia from 1979 to 1981 at a 1,000-bed voluntary hospital with 5,000 deliveries per year. all but three of the 30 neonates with blood cultures positive for ahsv presented within the first week of life. most were born at term and had good apgar scores. the majority of the infants were symptomatic, with respiratory distress being the most common presenting sign. other common signs included unexp ...	1984	6394019
clinical evaluation of a fluorescent antibody test for the serological diagnosis of streptococcal endocarditis.	serum fluorescent streptococcal antibody tests were carried out on 71 patients with clinically suspected infective endocarditis, and a final diagnosis of endocarditis was obtained in 46 patients. a serological diagnosis of streptococcal endocarditis was obtained in 10 patients who had persistently negative blood cultures, as fluorescent streptococcal antibody titres equal to or greater than 400 were detected against at least one of four strains of streptococci used as heterologous antigens. ther ...	1985	3881479
immunofluorescence studies of cardiac valves in infective endocarditis.	mitral and aortic valves removed at emergency cardiac surgery from a patient with infective endocarditis caused by streptococcus viridans were studied by immunofluorescence to ascertain the extent and pattern of various immune reactants within the large valvular vegetations. heavy intravalvular deposits of igg as well as bacterial antigen were present. much more focal interstitial igm and c3 deposits were noted within vegetations and valve substance. diffuse endocardial and subendocardial deposi ...	1985	3883933
infective endocarditis in adults in glasgow, 1976-81.	seventy-one cases of endocarditis in adults, defined on strict clinical criteria over a period of 5 years were studied. the demographic profile was similar to other published studies except that no bimodal peak in age distribution was detected. the major presenting features were infection, cardiac failure and embolism. rheumatic valvular disease (44%) was the most common predisposing condition. twenty percent of our patients developed endocarditis on an apparently normal valve and 28% presented ...	1985	3886562
current diagnosis of infective endocarditis.	an analysis was made of 91 cases of infective endocarditis (ie) with regard to causative organisms and their sensitivities to various antibiotics, the clinical features of the disease, the laboratory test results and other items were important in establishing a diagnosis of ie. the number of cases of ie has shown a tendency to increase in recent years, particularly in the number of elderly patients, and the ratio of total cases consisting of prosthetic valve endocarditis (pve) has shown a sharp ...	1985	3894710
[neonatal meningitis caused by streptococcus mitis].	we report on a female newborn, 37 weeks of gestational age, who - after normal pregnancy and delivery - fell ill with a neonatal meningitis caused by streptococcus mitis. until now this bacillus has been thought to be apathogen. the disease was cured completely by penicillin therapy. the infection of a healthy newborn caused by streptococcus mitis, a streptococcus viridans, has not been described before.	1985	3908918
peritonitis due to streptococcus viridans in patients receiving continuous ambulatory peritoneal dialysis.		1985	3919872
penicillin allergy and desensitization in serious infections during pregnancy.	penicillin allergy presents a major obstacle to the successful management of some antepartum infections. we studied 15 pregnant women with histories of penicillin allergy confirmed by positive immediate wheal-and-flare skin tests. thirteen had syphilis, one listeria sepsis, and one streptococcus viridans endocarditis. each patient was desensitized over four to six hours by oral administration of increasing doses of penicillin v. at the completion of the procedure, full-dose parenteral therapy wi ...	1985	3921835
mitral obstruction in bacterial endocarditis.	mitral obstruction due to a large vegetation of acute streptococcus viridans endocarditis occurred in a 47 year old man. serial echocardiography documented the rapid growth of the vegetation and its haemodynamic effects. emergency mitral valve replacement was performed too late to reverse the course of fatal septic shock.	1985	3970792
[prevention of bacterial endocarditis].	prevention of bacterial endocarditis is aimed at limiting the frequency, size, and duration of transient bacteremia with subsequent bacterial implantation on valvular endothelium in patients with cardiopathy. any procedure involving mucosa rich in normal flora or an infectious site can result in bacteremia, which can be minimized by selecting diagnostic and therapeutic procedures which are least traumatic. in addition, proper antibiotic prophylaxis should be administered according to the most fr ...	1985	3977268
streptococcus viridans vertebral osteomyelitis with bacteremia.		1985	3980198
[cause, facilitation or accident: haemophilus and streptococcus viridans polymicrobial endocarditis].		1985	3982141
streptococcus viridans bacteremia associated with atrial myxoma.		1985	4013981
septic arthritis of the acromioclavicular joint.	a patient with isolated pyogenous arthritis of the acromioclavicular joint (a-c joint) caused by streptococcus viridans is described. the patient had no underlying disease. minor trauma preceded shortly the development of the septic process. the patient was treated successfully with surgical drainage and antibiotics. to our knowledge this is the first case report of septic arthritis of the a-c joint caused by streptococcus viridans. the a-c joint is rarely involved in septic processes. even cond ...	1985	4015350
recent trend of chemotherapy for infective endocarditis in japan.	out of the 10 patients with infective endocarditis (ie) at kawasaki municipal hospital, 8 had ie due to streptococcus viridans. out of 8 patients with streptococcus ie, 6 were successfully treated with benzyl penicillin alone or in combination with kanamycin. one patient was cured with cephaloridine. two hundred and thirty ie patients admitted to hospitals at kantou district were also studied. ninety nine of 116 patients with streptococcus viridans ie were successfully treated with potentially a ...	1985	4021065
infective endocarditis in children.	the clinical manifestations, infective microorganisms, underlying diseases, complications and prognosis of infective endocarditis (ie) were studied in 17 current patients. data were compared with 101 previous cases reported in japan. most patients with ie (110/118 = 93.2%) had underlying heart diseases. ie was noted most often in patients with ventricular septal defect (vsd) and tetralogy of fallot. the incidence of post operative endocarditis was high (29.4% in the present series and 9.0% in th ...	1985	4021067
serious infection in a neonatal intensive care unit: a two-year survey.	over a two-year period 160 episodes of serious infection occurred in 139 infants admitted to a regional neonatal intensive-care unit. eighty-seven (26%) of very low birth weight (vlbw) neonates and 52 (8%) of infants of birth weight greater than 1500 g were infected. the majority (84%) had bacteraemia alone. though the clinical features of infection were not distinctive, in 94% of episodes the peripheral white blood cell or band counts were abnormal. thirty-three (21%) of the infections occurred ...	1985	4067290
septic arthritis due to aerococcus viridans.	a 20-year-old woman was found to have septic arthritis of the hip due to aerococcus viridans. this organism closely resembles streptococcus viridans, but forms gram positive tetrads rather than chains in broth media. the organism has been reported rarely to cause endocarditis and one case of osteomyelitis has been observed. to our knowledge septic arthritis due to aerococcus viridans has not been previously reported.	1985	4087248
dental bacteremia--a neglected cause of arthroplasty infections? three hip cases.	we report on three patients with late hip replacement infection. the micro-organism was microaerophilic streptococcus viridans, an oral organism, in all patients. dental procedures had preceded the onset of the hip infection in all cases, and severe periodontal disease was observed on subsequent admissions.	1985	4090954
polyclonal b cell hyperplasia associated with epstein-barr virus causing acute renal allograft failure.	six weeks post cadaver renal transplantation, a patient developed a flu-like illness. acute renal failure unresponsive to anti-rejection therapy occurred and he died four days later from pneumocystis carinii pneumonia and streptococcus viridans septicemia. autopsy revealed a diffuse polymorphic polyclonal b cell infiltrate occupying most organs, including the allograft. primary epstein-barr virus (ebv) infection was established by 1) rising anti-ebv antibody titres; 2) the demonstration of ebv n ...	1985	2994928
immunocompromised animal models for the study of antibiotic combinations.	studies of various models of pseudomonas aeruginosa infections in neutropenic animals have demonstrated the superiority of the combination of beta-lactam and aminoglycoside antibiotics when compared with a single drug alone. a limited number of studies carried out in models of klebsiella pneumoniae infections in neutropenic animals have shown similar results. the efficacy of double beta-lactam combinations for the treatment of gram-negative bacillary infections has not been studied as extensivel ...	1986	3087166
post-mortem bacterial culture of bronchial mucus and heart blood in hospital and non-hospital autopsies: effect of morgue time and length of hospitalization.	we studied cultures of 109 bronchial mucus and 67 heart blood specimens from unselected hospital autopsies and 40 bronchial mucus and heart blood specimens from unselected non-hospital (forensic) autopsies, performed 1-11 days after death. the most prevalent bacterium was streptococcus viridans. no association was found between morgue time and the number of species isolated from each bronchial mucus or heart blood specimen in either hospital or non-hospital autopsies, nor between morgue time and ...	1986	3096018
propionibacteria isolates and asymptomatic infections of the peritoneal effluent in capd patients.	during the past two years our laboratory has isolated propionibacterium-an anaerobic gram-positive rod-on 40 occasions from the drainage fluid of 25 patients on capd and eight on ipd. most patients had no symptoms and the fluid was sent for culture after treatment of peritonitis, during training period, and occasionally because it was cloudy. no association was found with patients' age, length on dialysis, or previous peritonitis episodes. the only statistically significant association (p = 0.03 ...	1986	3110672
new concept in chemoprophylaxis of bacterial endocarditis resulting from dental treatment.	bacteremia following dental procedures may lead to bacterial endocarditis in susceptible patients. traditional methods of chemoprophylaxis with a parenteral loading dose of penicillin followed by oral penicillin have proved impractical outside the hospital. in 1978, it was suggested in england that amoxicillin be substituted as the drug of choice in the prophylaxis of bacterial endocarditis. the recommended mode of treatment was a single oral dose of 3 g amoxicillin administered 1 hour before on ...	1986	3458144
extracranial mycotic aneurysms in infective endocarditis.	nine of 217 (4.15%) patients with infective endocarditis who were followed from october 1978 to february 1984 had extracranial mycotic aneurysms (ma). age range of patients was 6-43 years (mean of 24.8 years) and 7 were male. etiologic agents were streptococcus viridans (3 cases), staphylococcus aureus (2 cases), staphylococcus epidermidis (1 case), and pseudomonas aeruginosa (1 case). two patients had negative blood cultures. the ma involved the arteries of the limbs (5 cases), thoracic (3 case ...	1986	3512135
infectious crystalline keratopathy.	a 57-year-old white female was noted to have unusual intrastromal crystalline-like opacities in her failing right corneal graft five months after transplant surgery. cultures grew streptococcus viridans; since the graft was failing it was replaced and sent for pathologic examination. h&e stains revealed intrastromal pockets of basophilic material between the lamellae; there was a notable absence of inflammatory cells. gram's stain showed the basophilic material to be gram positive and transmissi ...	1986	3529469
bacteremia with gastrointestinal endoscopic procedures.	the authors have reviewed 40 prospective studies of bacteremia with gastrointestinal procedures. endoscopic procedures with a low mean frequency of bacteremia were esophagogastroduodenoscopy (4.2%), endoscopic retrograde cholangiopancreatography (5.6%), colonoscopy (2.2%), and sigmoidoscopy (4.9%). a higher mean frequency of bacteremia was encountered with esophageal dilation (45%) and variceal sclerotherapy (31%), although the number of patients studied was small. potentially pathogenic organis ...	1986	3533703
hemophilus influenzae and streptococcus viridans endocarditis in an intravenous drug abuser.		1986	3537870
bacterial antigens stimulate the production of histamine releasing factor (hrf) by lymphocytes from intrinsic asthmatic patients.	lymphocyte from 12 intrinsic asthmatic patients and 10 healthy controls were studied for their capability to produce histamine releasing factor (hrf) in vitro. spontaneous hrf production was measured by culturing the lymphocytes alone for 20 h. in another set of experiments lymphocytes were first preincubated separately with phytohaemagglutinin, antigens of haemophilus influenzae, streptococcus viridans, staphylococcus sp. and neisseria catarrhalis for 4 h then carefully washed three times and c ...	1986	2420497
infective endocarditis in swedish children. i. incidence, etiology, underlying factors and port of entry of infection.	a retrospective study of swedish children with infective endocarditis (ie) during the period 1971-80 was made. sixty-six instances were identified in 64 children (0.39 cases per 100,000 children per year). fifty (78%) had a previously known heart disease. most commonly this was a ventricular septal defect and tetralogy of fallot. seventy-one percent had positive blood cultures. streptococcus viridans and staphylococcus aureus were most commonly isolated. twenty-two percent of the children had un ...	1986	3564983
infective endocarditis in childhood.	a total of 37 cases of infective endocarditis, in children aged two days to 13 years, were seen from 1971 to 1983 at the children's hospital, camperdown. structural heart disease was known to preexist in 95%. cyanotic congenital heart disease was present in 15 children, of whom 11 had been palliated by a systemic-to-pulmonary artery shunt. in five children, there was infection of a prosthetic valve. identifiable precipitants of infection were rare. in particular, no child had had a preceding den ...	1986	3635143
mitral valve aneurysm formation documented by cross-sectional echocardiography.	we report a case of mitral valve aneurysm secondary to streptococcus viridans endocarditis of the mitral valve. cross-sectional echocardiography demonstrated an initial thickening of the anterior mitral leaflet which evolved further into an aneurysm. surgery showed that this lesion had subsequently perforated. this case highlights the ability of echocardiography to detect gradual anatomic changes in the course of bacterial endocarditis. the diagnosis of such abnormalities might have important th ...	1986	3699053
immunosuppressive therapy and plasmapheresis in rapidly progressive glomerulonephritis associated with bacterial endocarditis.	a 25-year-old male presented with new cardiac murmurs and acute renal insufficiency. blood cultures grew streptococcus viridans and appropriate antibiotic therapy was initiated. a renal biopsy revealed diffuse proliferative glomerulonephritis with crescents involving more than 50% of the glomeruli. treatment with antibiotics, plasmapheresis, and steroids resulted in renal recovery that paralleled reductions in circulating immune complexes. the rationale for this therapeutic approach is discussed ...	1986	3706297
effect of chlorhexidine 0.5% on the hand bacterial flora.	the effects of cleaning the dorsal hand with chlorhexidine 0.5% in spirit was evaluated by bacteriological study in 45 adult patients. in the absence of cleaning it was found that the prevalent microorganisms were staphylococcus epidermidis, staphylococcus aureus, streptococcus viridans and enterobacteriaceae. cleaning the hand with chlorhexidine 0.5% eliminated all bacteria except s. epidermidis and s. aureus. in both instances, the culture results showed that the microorganisms were present in ...	1986	3776454
[spondylitis caused by the non-hemolytic streptococcus viridans mitis].		1986	3787842
infective endocarditis in children: a current diagnostic trend and the embolic complications.	twenty-three cases of ie, of which 91% had underlying congenital heart diseases were diagnosed by positive blood culture or vegetative lesion detected by 2-d echo when a patient revealed clinically suspicious episodes. vsd and tof were the most common underlying heart diseases. the vegetation was detected successfully by 2-d echo in 91% of the cases. the causative organisms were identified in 83% of the cases. streptococcus viridans and staphylococcus aureus were the two major organisms detected ...	1986	3820538
[extra-hospital streptococcus viridans pneumonia].		1987	3821252
factors influencing mortality from infective endocarditis in two district general hospitals.	factors influencing mortality were studied in 92 consecutive cases of infective endocarditis admitted to two district general hospitals between january 1975 and april 1982. thirty two patients died, an overall mortality of 35%, 13 patients died before diagnosis and 19 despite aggressive antimicrobial therapy. bactericidal antibiotic levels were monitored in 39 cases but these did not appear to influence outcome. mortality was lowest for streptococcus viridans infection (15%) but rose to 50% for ...	1987	3671266
[identification of streptococcus viridans in clinical specimens].	in a 4 year prospective study of "viridans" or non-groupable streptococci 100 clinically significant strains were isolated. strains were defined as significant when found in two or more samples of blood cultures, or when seen on gram staining together with inflammatory reaction. fifty-two strains were speciated by 10 physiological characteristics. in 42 cases additional tests were performed. only 16 isolates were unidentifiable by the techniques used. sources of isolates included purulent lesion ...	1987	3685392
bacteriological quality of raw human milk: effect of storage in a refrigerator.	eighty-seven breast milk samples were obtained from 63 mothers of infants on the neonatal intensive care unit of the lagos university teaching hospital. the samples were cultured for bacteria immediately after collection (0 h) and then stored in a domestic refrigerator from where cultures were repeated at 6-hourly intervals for 24 h. at 0 h, three (3.4%) of the samples were sterile; 56 (64%) grew coagulase negative staphylococci, and one (1.1%) streptococcus viridans. thus, 60 (69%) of the sampl ...	1987	2449844
[bacterial endocarditis caused by streptococcus viridans disclosed by sacroiliitis].		1987	3563374
[pleural empyema due to streptococcus milleri].	thus far little attention has been focused on the precise identification of streptococcus viridans to species level and the clinical relevance of streptococcus milleri, yet there is growing evidence that closer identification would be of significant clinical value. streptococcus milleri was identified in 142 isolates from approximately 120 patients over a period of 12 months (june 1984-may 1985) at the institute of medical microbiology, zurich university hospital. pleural empyema was the source ...	1987	3303315
acanthamoeba keratitis and infectious crystalline keratopathy.	two cases of acanthamoeba keratitis and infectious crystalline keratopathy, occurring simultaneously, are presented. three and 12 months after initiating topical corticosteroid therapy in cases 1 and 2, respectively, alpha-hemolytic streptococcus viridans was cultured from each cornea. topical corticosteroid therapy was initiated for the treatment of an annular stromal opacity, presumably secondary to herpes simplex keratitis. acanthamoeba was identified in culture following penetrating keratopl ...	1987	3314824
corneal rim cultures.	we performed a retrospective analysis of 291 consecutive scleral rim cultures, taken at the time of corneal transplantation, from 1981 to 1986. there were 82 positive cultures (39%), and the most common pathogen was staphylococcus epidermidis, with 24 positive cultures (30%). ten of these (42%) were resistant to gentamycin. there were no cases of endophthalmitis or other infections in the immediate postoperative period. we also found 15 positive cultures of streptococcus viridans. of these, 13 ( ...	1987	3315460
preterm labor: stimulation of arachidonic acid metabolism in human amnion cells by bacterial products.	there is a strong association between preterm labor and infection. some potentially pathogenic bacteria have phospholipase activity, and it has been suggested that release of phospholipase from these organisms may increase prostaglandin e2 synthesis in amnion cells and hence initiate preterm labor. in this study we established monolayer amnion cell cultures from tissue collected at elective cesarean section at term before labor. cells were prelabeled with tritiated arachidonic acid and then furt ...	1987	3103451
in vitro activity of ro 15-8074 and ro 19-5247.	the in vitro activity of ro 15-8074 (cefetamet) and ro 19-5247, new oral cephalosporins, was compared with that of amoxicillin, cephalexin, cefaclor, cefuroxime and erythromycin against 292 clinical isolates using the agar dilution method. both ro 15-8074 and ro 19-5247 were very active against proteus mirabilis, neisseria gonorrhoeae, haemophilus influenzae and streptococcus pyogenes, but less active against staphylococcus saprophyticus and enterobacter cloacae. ro 19-5247 was more active than ...	1987	3109897
pharmacokinetic and in vivo studies with azithromycin (cp-62,993), a new macrolide with an extended half-life and excellent tissue distribution.	azithromycin (cp-62,993), a new acid-stable 15-membered-ring macrolide, was well absorbed following oral administration in mice, rats, dogs, and cynomolgus monkeys. this compound exhibited a uniformly long elimination half-life and was distributed exceptionally well into all tissues. this extravascular penetration of azithromycin was demonstrated by tissue/plasma area-under-the-curve ratios ranging from 13.6 to 137 compared with ratios for erythromycin of 3.1 to 11.6. the significance of these p ...	1987	2830841
[streptococcal abscesses of the liver: diagnosis and therapy using ultrasound controlled puncture].	three male patients without accompanying diseases, 27, 47, and 52 years of age, were admitted with fever of unknown origin. focal liver disease was seen on ultrasound and the diagnosis of an abscess was confirmed by sonographically-guided fine-needle puncture. microaerophilic streptococci were found in two cases, streptococcus viridans once. two patients had cryptogenic abscesses; one had previously undergone surgery for a rectal abscess. all three patients were cured of their condition by appro ...	1988	3047863
relationship of surveillance cultures to bacteremia and fungemia in bone marrow transplant recipients with hickman or broviac catheters.	a total of 64 episodes of bacteremia and fungemia were documented in 25 allogeneic bone marrow transplant recipients. coagulase-negative staphylococci were the most common pathogens recovered, with 34 of the 39 isolated being methicillin resistant. streptococcus viridans (11 episodes), diphtheroids (5 episodes), and pseudomonas aeruginosa (4 episodes) accounted for the majority of the other pathogens causing bacteremia. six episodes of fungemia were also seen. coagulase-negative staphylococci we ...	1988	3054334
left atrial myxoma infected with streptococcus viridans.	a case is described of streptococcus viridans endocarditis involving a left atrial myxoma. the diagnosis was made by echocardiography and the infected tumour was successfully treated by surgical removal. a review of the published literature about left atrial myxomas underlines the importance of performing echocardiography in all patients with suspected endocarditis.	1988	3068157