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the effect of removal of the coagulum in the alveolus before replantation upon periodontal and pulpal healing of mature permanent incisors in monkeys.the effect of removal of the coagulum in the alveolus before replantation upon periodontal and pulpal healing was studied in green vervet monkeys (cercopithecus aethiops). mandibular lateral incisors were extracted. the extra-alveolar period before replantation was 60 min. the storage medium for the extracted teeth was physiologic saline. on the right side of the mandible, the coagulum was removed before replantation, using syringe with saline assisted by a spoon-shaped excavator. on the left si ...19806783573
a time-related study of periodontal healing and root resorption activity after replantation of mature permanent incisors in monkeys.periodontal and pulpal healing was registered histometrically at different observation periods after replantation of mature incisors in green vervet monkeys. maxillary central incisors and mandibular lateral incisors were extracted and then replanted after either 0- to 18 min. in the 18 min. group, the teeth were stored dry prior to replantation. the animals were sacrificed 1-, 2-, 4-, or 8 weeks after replantation. the mobility of the replanted teeth was determined and histological examination ...19806933704
analysis of pathogenesis and topography of replacement root resorption (ankylosis) after replantation of mature permanent incisors in monkeys.the pathogenesis and topography of replacement root resorption (ankylosis) after replantation of incisors was examined in green vervet monkeys (cercopithecus aethiops). incisors were replanted after 0,18 or 120 min. storage and examined histometrically for replacement resorption after 2, 4 and 8 weeks. there was a significant preference for certain locations upon the root surface. thus, ankylosis was found significantly more often on the rounded labial and lingual surfaces than on the flat or co ...19806938062
the structure of social space among a captive group of vervet monkeys.proximity data collected during a 34-month longitudinal study of captive vervets are used to generate a quantitative, predictive model consistent with age, gender, kinship, and dominance status variables. differential ontogenetic patterns of uterine and non-uterine passive contact and nearness are described for males and females, illustrating decreased distance with age in females and increased disperson for males. proximal relationships are structured by kinship, although not uniformly across g ...19807216003
steroid excretion during the reporductive cycle and in pregnanacy of the vervet monkey (cercopithecus aethiopus pygerythrus). 19807421223
electrocardiographic studies in african green monkeys (cercopithecus aethiops).electrocardiograms obtained as part of a pre-experimental clinical examination were analyzed for a newly purchased group of 46 male african green vervets. in general, they were similar to electrocardiograms reported for other old world species. an unexpectedly high prevalence (17%) of electrocardiogram abnormalities was found in this young (4--6 years of age) vervet population. the main abnormalities were nonspecific t wave flattening, left axis deviation, peaked p waves, rsr' patterns, and abno ...19807431868
excretion, isolation and structure of a new phenolic constituent of female urine.the regular occurrence of a peak due to an unidentified substance (x) in the gas chromatographic traces obtained from phenolic extracts of urine from human pregnant and non-pregnant females has been reported. the biphasic excretion of x with maxima in the luteal phase of the ovulatory cycle and relatively high levels in the first trimester of pregnancy were noteworthy and suggested that the substance may have a biological significance. close similarities between the excretory pattern, the chemic ...19807432490
monkey responses to three different alarm calls: evidence of predator classification and semantic communication.vervet monkeys give different alarm calls to different predators. recordings of the alarms played back when predators were absent caused the monkeys to run into trees for leopard alarms, look up for eagle alarms, and look down for snake alarms. adults call primarily to leopards, martial eagles, and pythons, but infants give leopard alarms to various mammals, eagle alarms to many birds, and snake alarms to various snakelike objects. predator classification improves with age and experience.19807433999
observations on the inter-troop movement of adult vervet monkeys (cercopithecus aethiops).vervet troops are not closed units and migration - both into and out of the troop - occurs regularly. available data suggest that it is a male phenomenon related to the accessibility of adult females. the process and its implications are discussed.19807191819
meal timing alters circadian rhythm of skin surface temperature in non-human primates.circadian rhythms of skin surface temperature were demonstrated in a group of african green vervets. alteration of the timing of a single daily meal of fixed caloric content resulted in a shift of the skin surface temperature acrophase in 7 of the 8 series. the timing of the individual temperature acrophases in relation to the light-dark cycle and the extent of acrophase shift in response to alteration of meal timing showed considerable variation between the individual animals studied.19807450921
the definitive identification of the lignans trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone and 2,3-bis(3-hydroxybenzyl)butane-1,4-diol in human and animal urine.the definitive identification of the first lignans to be found in humans and animals is described. gas chromatography--mass spectrometry, n.m.r. spectroscopy, i.r. spectroscopy and chemical techniques were employed to establish the structures of two lignans as trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone and 2,3-bis(3-hydroxybenzyl)butane-1,4-diol. both compounds are essetially racemic. evidence was also found for several methoxy analogues of these lignans in the vervet monkey.19817325966
the effect of praziquantel on schistosoma haematobium, s. japonicum and s. mansoni in primates.baboons infected with s. haematobium and vervet monkeys infected with s. japonicum were treated orally with different dosage regimens of 2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino[2,1-a]isoquinolin-4-on e(praziquantel, embay 8440, biltricide) and were autopsied and perfused 3--4 months after treatment. the results suggest that a single oral dose of 75--100 mg/kg body weight is likely to be effective against s. haematobium in the baboon. female worms of s. haematobium are apparently ...19817195244
intergroup encounters among free-ranging vervet monkeys.high-ranking vervet monkeys threatened the members of other groups more than did low-ranking individuals, while only low-ranking females and juvenile males interacted affinitively with the members of other groups. adult males were most aggressive during intergroup encounters with groups from which males transferred. in contrast, females were most aggressive to groups from which males were not observed to transfer. it is postulated that the behavior of individuals during intergroup encounters may ...19817196367
endemic enteric disease in vervet monkeys.comprehensive bacteriological investigation indicates shigellae as the probable aetiological bacteria in one endemic enteric disease situation. one species and four serotypes have been detected. in vitro antibiotic sensitivity spectra have been determined. epidemiology, pathology and pathogenesis in relation to the experimental animal situation and experimental results are considered. a rationale for treatment and control is suggested.19817031245
identification of acidic steroids in feces of monkeys fed beta-sitoserol.vervet monkeys were fed a suspension of beta-sitoseterol in corn oil. acidic steroids were separated from a 4-day pool of feces and subjected, after fractionation, to gas liquid chromatography and mass spectrometry. evidence for the presence of derivatives of 27-carboxysitosterol, 27-carboxysitostanol and 7-hydroxy, 27-carboxysitostanol is adduced.19817219084
nutritional effects on blood lipid and hdl cholesterol concentrations in two subspecies of african green monkeys (cercopithecus aethiops).the african green monkey has previously been found to be a promising model for the study of atherosclerosis. we have compared the plasma and hdl cholesterol response to dietary manipulation in the two subspecies of african green monkeys (vervets and grivets) most often imported for biomedical research purposes. twenty vervets and 20 grivets were fed, in succession, diets containing safflower oil, butter, or lard as the principal dietary fat at a level of 40% of calories. ten animals of each subs ...19817240958
blood protein variation in a population of ethiopian vervet monkeys (cercopithecus aethiops aethiops).seven small groups of vervet monkeys (cercopithecus aethiops aethiops), totaling 124 individuals, from awash national park, ethiopia, were trapped and blood samples were obtained. twenty-three loci were examined by starch gel electrophoresis and four loci, tf, e, ada, and pmg2 were found to be polymorphic. the average heterozygosity (h) of the population was calculated to be 5.6%. no significant deviations from hardy-weinberg equilibrium proportions occurred and a chi-square test for group homog ...19817258346
effect of orbitofrontal and temporal neocortical lesions of the affiliative behavior of vervet monkeys (cercopithecus aethiops sabaeus). 19817262243
haptic to visual cross-modal recognition of objects in the vervet monkey.five juvenile vervet monkeys (cercopithecus aethiops) were tested using the cowey and weiskrantz technique. the animals had access in the dark to distasteful biscuits of one shape and tasteful biscuits of another shape. later they were shown a pair of biscuits, one of each shape, and the animal’s first selection was scored. a single pair of shapes was used with flavor assigned daily according to a gellerman schedule. in 69 percent of trials the monkeys selected the tasteful shape (p less than 0. ...19817270253
response of small intestinal flora to elemental diet and pancreatic duct ligation in vervet monkey.the small intestinal flora of vervet monkeys (cercopithecus aethiops) was examined before and after feeding elemental diet and after ligation of the pancreatic duct. elemental diet did not produce significant changes of the intestinal microbial flora. however, an increase of the microbial count consisting mainly of enterobacteriaceae, molds and yeasts was observed in the duct-ligated animals, significantly more pronounced than in the sham-operated controls. the data confirm previous studies demo ...19817277464
attempted transmission of canine ehrlichiosis to the vervet monkey (cercopithecus pygerythrus).blood from a domestic dog infected with ehrlichia canis was injected into 3 adult vervet monkeys cercopithecus pygerythrus. the monkeys did not develop any clinical or haematological signs of disease, nor did they seem to be able to harbour the parasite. furthermore, neither morulae of e. canis nor haematological evidence of ehrlichiosis were seen after these monkeys had been splenectomized. the splenectomized monkeys did, however, develop a severe parasitaemia of their red cells with entopolypo ...19817312306
a comparative study of culturally transmitted patterns of feeding habits in the chacma baboon papio ursinus and the vervet monkey cercopithecus aethiops.japanese workers have studied social acquisition patterns of new feeding habits in macaca fuscata which they have termed precultural. the present study investigates the same phenomenon in the chacma baboon and the vervet monkey in their natural habitat. the questions addressed are: (1) how a new feeding habit enters a troop and by which age and sex category, also how it is propagated? (2) when individuals are permitted with a choice between palatable and unpalatable food, can they learn by demon ...19817319426
the effect of limited drying or removal of the periodontal ligament. periodontal healing after replantation of mature permanent incisors in monkeys.the effect of limited drying or removal of the periodontal ligament upon periodontal healing after replantation of incisors was studied in green vervet monkeys. all teeth were examined histologically either 2-, 4- or 8 weeks after replantation. the drying experiment demonstrated that an area of ankylosis was established after 2 weeks corresponding to the dried portion of the root and was removed by a resorptive process in the majority of cases after 8 weeks. the removal of the periodontal ligame ...19816943904
relationship between cell damage in the periodontal ligament after replantation and subsequent development of root resorption. a time-related study in monkeys.the etiology of root resorption subsequent to replantation of incisors was examined in green vervet monkeys. cell damage to the root surface due to the extraction procedures was registered histologically 1 week after replantation. the topographical distribution of cell damage was then related to the development of root resorption in similar replanted teeth with longer observation periods. histometric analysis showed that surface-, inflammatory- and replacement resorption was significantly relate ...19816943905
the effect of excessive occlusal trauma upon periodontal healing after replantation of mature permanent incisors in monkeys.the effect of excessive occlusal force upon periodontal healing after replantation of mature permanent incisors was studied in green vervet monkeys. the extra-alveolar period before replantation was 120 min. prior to replantation, the teeth were root filled with gutta percha. the material consisted of four groups. in the two control groups, either no splinting or splinting for 2 weeks was used. in the first experimental group, a stainless steel crown was cemented on the antagonist of the replant ...19816947468
peripheral correlates of serotonergically-influenced behaviors in vervet monkeys (cercopithecus aethiops sabaeus).the associations among twelve behaviors and three potential peripheral markers of central serotonergic activity were investigated in vervet monkeys (cercopithecus aethiops sabaeus). the behaviors monitored included approach, heterogroom, rest, eat, avoid, be solitary, be vigilant, huddle, initiate aggress, receive aggress, and engage in sexual behavior. the biochemical parameters measured were whole blood serotonin, plasma free tryptophan, and plasma total tryptophan. throughout the study period ...19816784141
immunohistochemical localization of fsh and lh in the pars distalis of vervet (cercopithecus aethiops) and baboon (papio hamadryas) pituitaries.antisera against olh, beta olh and beta hfsh were used to localize gonadotropic cells in the pars distalis of cercopithecus aethiops and papio hamadryas. three separate cell types were observed for fsh and lh: 85% of immunohistochemically identified gonadotropic cells reacted to all the various antisera; 10% reacted with the anti-beta olh antibody only; and 5% with the anti-beta hfsh antibody only. comparisons between adjacent serial sections treated with various antisera, other than anti-gonado ...19816786752
effect of chronic amphetamine administration on central dopaminergic mechanisms in the vervet.a biochemical study of central dopaminergic mechanisms was carried out in brain tissue from vervet monkeys who had been subjected to chronic amphetamine administration. the brain concentrations of dopamine (da) and 3,4-dihydroxyphenylacetic acid (dopac) were markedly reduced. significant reductions were also observed in the activities of dopa-decarboxylase (ddc) and tyrosine hydroxylase (th). a kinetic study of th revealed a 60% reduction in maximum reaction velocity, consistent with destruction ...19816791228
effect of extra-alveolar period and storage media upon periodontal and pulpal healing after replantation of mature permanent incisors in monkeys.the effect of extra-alveolar period and storage media upon periodontal and pulpal healing after replantation was studied in green vervet monkeys (cercopithecus aethiops). mandibular lateral incisors were extracted. the extra-alveolar period before replantation was 0, 18, 30, 60, 90, and 120 min. the storage media for the extracted teeth were tap water, physiologic saline, saliva or dry storage. the animals were sacrificed 8 weeks after replantation and the replanted teeth were examined histometr ...19816792094
periodontal healing after replantation and autotransplantation of incisors in monkeys.the effect of injury to the cemental or alveolar part of the periodontal ligament upon periodontal healing after replantation and autotransplantation of teeth was studied in green vervet monkeys. sixty-six maxillary central incisors were replanted or autotransplanted after extra-alveolar periods of 18 min. saline storage or 120 min. dry storage. the animals were sacrificed after 8 weeks and the teeth examined histometrically. identical healing was found in the following experimental groups: repl ...19816792095
effect of cutting speeds and a cavity liner on the pulpal response to nobetec.the investigation was undertaken to determine the response to nobetec, a modified zinc oxide-eugenol cement, widely used as a negative control material in pulpal studies, under conditions of high- and low-speed cavity preparation, with and without a cavity liner dycal. the pulpal responses were evaluated at intervals of 2 days, 2 weeks and 8 weeks in the permanent maxillary and mandibular incisors in 26 vervet monkeys using labial class v cavities prepared in 208 teeth. nobetec was found to be m ...19816792335
evaluation of different types of autotransplanted connective tissues as potential periodontal ligament substitutes. an experimental replantation study in monkeys.the purpose of the present study was to investigate connective tissue autotransplants as potential periodontal ligament substitutes. green vervet monkeys (cercopithecus aethiops) were used. maxillary permanent central incisors were extracted, root filled extraorally and the periodontal ligament removed from the root surface and the socket wall. two circular cavities were prepared mesially and distally on the root surface. different types of connective tissue autotransplants were then placed in t ...19816797974
aortic sudanophilia an zinc-copper ratios in the liver of vervet monkeys fed different types of dietary fibre.vervet monkeys (cercopithecus aethiops pygerethrus) were fed a semipurified diet containing 40% sucrose, 25% casein, 14% hydrogenated coconut oil and 15% fibre for 6 months. alfalfa, cellulose, or wheat straw was the source of the fibre. all the diets led to aortic sudanophilia, but the group fed wheat straw had the highest copper level in the liver and the least sudanophilia. the order to severity of the sudanophilia, the ratio of zinc to copper in the fibers, and the ratio of zinc to copper in ...19816164104
laboratory vector studies on six mosquito and one tick species with chikungunya virus.the tick ornithodoros savignyi and the mosquitoes culex horridus, culex quinquefasciatus, aedes fulgens, ae. furcifer and mansonia africana were tested for infection rates and ability to transmit chikungunya virus. o. savignyi and cx quinquefasciatus did not become infected and cx quinquefasciatus failed to transmit the virus between vervet monkeys, cercopithecus aethiops. only one of 17 cx horridus feeding on a blood-virus mixture became infected which included infection of the salivary glands. ...19816115488
technical note: urine collection from vervet monkeys by instrumental conditioning.gang-caged adult male vervet monkeys were trained to urinate on demand into a plastic beaker by positive reinforcement (peanut rewards). the animals were not separated from their social group during training or sampling.198131995942
longitudinal stability in adult status hierarchies among vervet monkeys (cercopithecus aethiops).status hierarchies were examined in a captive group over a 12-year period (1968-1979) to establish the stability and structure of vervet monkey dominance relationships. dyadic records of spontaneous avoid, bite, chase, and supplant behaviors are summarized into a win/lose matrix to produce a rank order of status at the end of each calendar year. the 13,717 agonistic acts tabulated are drawn from both focal and ad lib data. relative rank is computed by dividing the rank position of each individua ...198232197560
diagonal walking in captive infant vervet monkeys.the frequency of use of diagonal walking by three motorically immature vervet monkeys (cercopithecus aethiops) is discussed. the subjects were housed at the balcones research center (austin, texas) and ranged from 15-105 days of age. mixed longitudinal data taken from film indicated that lateral walknig was the first gait employed by the infant vervets studied, but that diagonal walking completely replaced lateral walking by 81 days of age. these data were compared with those of captive infant m ...198231995905
note on aversion learning to the shape of food by monkeys.vervet and grivet monkeys were repeatedly tested eating bar- and circle-shaped cookies. one subject was always injected with lithium immediately after eating cookies with the circle shape and learned to avoid the circular cookies while continuing to eat the bar-shaped cookies. another subject received similar treatment except that lithium injections were always delayed 30 minutes after access to the circle-shaped cookies. she also acquired a discriminative aversion. aversion learning was not obs ...198216812287
behavioural and biochemical effects of chronic amphetamine treatment in the vervet monkey.five vervet monkeys were administered increasing doses (4--12 mg/kg/day) of d-amphetamine over a period of 35 days. three phases od behavioural change were discerned: phase 1 during which animals exhibited repetitive stereotyped action sequences with rapid head movements, occasional abnormal grooming, picking at the cage, hand-staring and snatching; phase 2 in which behaviour became progressively more restricted and animals became markedly unresponsive to auditory, visual and tactile stimuli; ph ...19826130556
increased circulating levels of an endogenous digoxin-like factor in hypertensive monkeys.an endogenous, immunoreactive digoxin-like factor (endoxin) was measured in the plasma of nonhuman primates with hypertension. both normotensive and hypertensive rhesus monkeys had levels of endoxin that significantly correlated with their systolic or diastolic blood pressure. vervet monkeys with experimentally produced chronic goldblatt hypertension had significantly elevated endoxin, but not plasma renin. these data suggest that increased plasma endoxin may be a contributing factor in the deve ...19826279495
clonidine suppression of noradrenergic hyperactivity during morphine withdrawal by clonidine: biochemical studies in rodents and primates.in rodents, naloxone-precipitated withdrawal of morphine-dependent animals causes an increase in ne turnover and mhpg accumulation in certain regions of the brain. this increase in ne turnover and mhpg accumulation is suppressed by clonidine to a dose-dependent degree via a naloxone-insensitive mechanism. in general, drugs which have been shown by electrophysiological studies to cause changes in the activity of ne neurons in the locus coeruleus also alter the brain levels of mhpg. these studies ...19826806253
marburg, ebola and rift valley fever virus antibodies in east african primates.sera from 464 primates held at four institutes in kenya were tested by indirect immunofluorescence for the presence of antibodies against marburg, ebola, congo haemorrhagic fever, rift valley fever and lassa viruses. four of 136 vervet monkeys were positive for marburg virus antibodies and three of 184 baboons had antibodies against ebola virus. one baboon was positive for marburg virus antibodies. two vervet monkeys, three baboons and one grivet monkey (of 56 tested) had antibodies against rift ...19826810518
trans fatty acid effects in experimental atherosclerosis.trans unsaturated fatty acids are formed during hydrogenation of edible oils and their consumption in the united states has increased with increasing utilization of margarines. the effect of elaidic acid and trielaidin on atherosclerosis in cholesterol-fed rabbits were studied many years ago by weigensberg and mcmillan, who found these fatty acids to be significantly more hypercholesterolemic but not more atherogenic. jackson et al. have found that trans fatty acids are not inordinately atheroge ...19826811329
hepatocystis parasitemia in wild kenya vervet monkeys (cercopithecus aethiops).blood smears of 159 vervet monkeys from three sites in kenya were stained with giemsa and examined for hepatocystis parasites. the populations differ in incidence of parasitemia, ranging from 0-62% affected individuals. these differences are probably due to altitude and local environmental conditions.19826820806
the oral pathological conditions of the hard tissues of the vervet monkey in their natural environment. 19826959940
influence of native and randomized peanut oil on lipid metabolism and aortic sudanophilia in the vervet monkey.vervet monkeys (cercopithecus aethiops pygerethrus) were fed cholesterol-free, semipurified diets containing 40% sucrose, 25% casein, 15% cellulose and 14% peanut oil (pno), randomized peanut oil (rpno) or corn oil (co). after 4 months, serum cholesterol and triglyceride levels, serum lecithin-cholesterol acyl transferase (lcat) activity and plasma lipoprotein lipase (lpl) activity were similar in all groups. livers of monkeys fed co converted 156% more acetate and 24% more mevalonate to cholest ...19827082418
histochemical localization of acetylcholinesterase in the wall of cardiac blood vessels in the baboon, dog and vervet monkey.histochemical methods were used to demonstrate acetylcholinesterase in the wall of cardiac blood vessels in the baboon, dog and vervet monkey. to remove cholinesterase-containing sympathetic nerves, some of the animals were treated with guanethidine for four weeks prior to being sacrificed. in cardiac muscle from the dog and the vervet monkey, cholinergic nerves were histochemically visualized in both small and large vessels. on the other hand, in cardiac muscle from baboons, cholinergic nerves ...19827092779
trypanosoma brucei rhodesiense infection in vervet monkeys. i. parasitologic, hematologic, immunologic and histologic results.twenty vervet monkeys infected with t. rhodesiense (eatro 1989) developed chronic disease with an average duration of 65 days (variation 35-107 days). with respect to the course of the disease, and to the hematologic, immunologic and histological findings, the disease faithfully mirrored human t. rhodesiense infection. in all animals, parasitization of the csf occurred only a few weeks after infection, and was accompanied by an increase in the cell count and the appearance of igm in the csf. the ...19827164166
trypanosoma brucei rhodesiense infection in vervet monkeys. ii. provocation of the encephalitic late phase by treatment of infected monkeys.four out of 8 monkeys infected with trypanosoma rhodesiense and treated with trypanocidal drugs at various intervals after infection (days 55-58, days 62-65, day 68) developed encephalitis. in 2 of these animals, killed 2 weeks after treatment, the encephalitis presenting was incipient; the other 2 monkeys died as a result of severe encephalitis a little more than 2 and 3 months after treatment, respectively. at the time of treatment, the animals revealed a parasitization of the csf, but there w ...19827164167
serum aminopeptidases in pregnant vervet monkeys (cercopithecus aethiops).two distinctive aminopeptidase isozymes have been identified in the serum of the vervet monkey. the l-methionine-sensitive cytosol aminopeptidase (ap; e.c. 3.4.11.1) is present in all samples, while the cystyl aminopeptidase (cap; e.c. 3.4.11.3) isozyme, which is resistant to inhibition by 0.1 m l-methionine, is found only in the serum of pregnant females. the pregnancy-specific cap isozyme appears in the serum between the fifth and the eleventh weeks of a nearly 22-week pregnancy. the overall a ...19827181846
plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (mhpg) as indices of brain norepinephrine metabolism in primates.the relationship between mhpg concentration in several brain areas, cisternal csf and plasma was examined in 26 vervet monkeys. free mhpg was measured by gas chromatography-mass spectrometry using deuterated mhpg as internal standard. in animals with or without treatment with drugs that alter norepinephrine metabolism, highly significant correlations were found in concentrations of mhpg between the various brain areas, between plasma and csf, between plasma and brain areas and between csf and br ...19827188317
scanning electron microscope observations on the tubule content of freeze-fractured peripheral vervet monkey dentine (cercopithecus pygerythrus).pulp tissue in the incisors was fixed in situ by perfusion. cervical thirds of the tooth crowns were excised by sectioning the teeth transversely and cryofractured through the long axis of the tooth in a bucco-lingual mid-axial plane to expose the dentine from the pulp to the enamel-dentine junction. specimens were freeze-dried and the fracture surfaces examined by scanning electron microscopy. flattened tubular processes were noted protruding from the open ends of transversely fractured dentina ...19836574738
igg and igm--levels in serum and csf of t. rhodesiense-infected vervet monkeys. 19836825439
lipoprotein separation and low density lipoprotein molecular weight determination using high performance gel-filtration chromatography.plasma lipoproteins were isolated at d less than 1.225 g/ml from nonhuman primates of three species, cynomolgus, rhesus, and african green (vervet) monkeys. individual lipoprotein classes were separated by high performance gelfiltration chromatography and low density lipoprotein (ldl) molecular weight was determined. a comparison was made using column configurations including tsk 3000 sw, 4000 sw, and 5000 pw columns. due to its relative simplicity, stability, and economy, a single 5000 pw colum ...19836833895
patterns of genetic variability in the serum proteins of the kenyan vervet monkey (cercopithecus aethiops).an electrophoretic survey of 13 serum proteins was carried out on samples drawn from 340 vervet monkeys (cercopithecus aethiops) living in 30 troops from four different localities in central and southern kenya. the proportion of polymorphic loci is 0.17 and the average heterozygosity is 0.05. the group specific component, prealbumin carboxylesterase, and transferrin are all polymorphic. the analysis of the patterns of gene diversity show that a large part of the genic variation exists within ind ...19836869512
protein counterparts of human and simian cytomegaloviruses.cytomegalovirus (cmv) proteins from isolates of both human (hcmv) and simian (scmv) origin have been compared. three classes were analyzed: the immediate-early (ie) proteins, other infected-cell-specific proteins not present in virus particles, and the proteins that constitute the mature extracellular virion. comparisons were based on one- and two-dimensional (charge-size) separations in denaturing polyacrylamide gels, and on the selectivity of biosynthetic radiolabeling with [32p]orthophosphate ...19836310864
male dominance, serotonergic systems, and the behavioral and physiological effects of drugs in vervet monkeys (cercopithecus aethiops sabaeus). 19836316362
some histological aspects of the palmar digital pads in the vervet monkey.the structural organisation of the digital touch pads has been investigated in the vervet monkey (cercopithecus pygerythrus) by light microscopy. it has been demonstrated that the subcutaneous tissue of the terminal digital pad consists of a highly organised septal framework containing large amounts of elastic fibres, with adipose tissue sweat gland compartments lying between the connective tissue septa. it is suggested that the presence of elastic fibres in the septal framework of the terminal ...19836654269
cardiac lymph drainage in experimental african trypanosomiasis in vervet monkeys.in group i (15 monkeys) the infection time was less than 70 days with one exception and histologically 14 had trypanosomal pancarditis with morphological evidence of lymph stasis. trypanosomes served as markers of the dilated cardiac lymphatics seen at apices, atrioventricular junctions, near the his bundle, at the base of cardiac valves and around the root of the aorta and pulmonary artery. 3 hearts had apical aneurysms. in group ii (6 monkeys) the infection time exceeded 130 days and despite s ...19836673854
long-term infection of schistosoma mansoni in a vervet monkey (cercopithecus aethiops).schistosoma mansoni infection in cercopithecus species monkeys has been previously monitored for up to five years. this is an account of observations made during an autopsy on a male vervet monkey which had harboured the parasite for 15 years. viable eggs had been recovered from the faeces throughout the infection, being hatched to observe the emergence of miracidia. apart from a nodular appearance of the liver capsule, which was noted before the perfusion, and localized haemorrhaging in the lar ...19836679365
plasma cortisol response to feeding in african green vervets.the timing of a single daily meal of monkey chow in african green vervets exerts a synchronizing influence on plasma cortisol concentrations with an initial increase after feeding followed by a decrease to minimal levels five hours after feeding.19836680136
a preliminary description of acute physical dependence on morphine in the vervet monkey.previous animal studies have suggested the rapid development of opiate dependency in 24 hours or less. however, the development of dependence on opioids within twenty-four hours has yet to be demonstrated in previously opiate-free human or nonhuman primate subjects. following naloxone administration, cable-restrained monkeys which received intravenous morphine hourly for only six hours exhibited a behavioral syndrome characteristic of opioid withdrawal in this particular species. these data indi ...19836682230
behavioural and biochemical effects of chronic treatment with amphetamine in the vervet monkey. 19836682939
reserpine as an uncoupler of oxidative phosphorylation and the relevance to its psychoactive properties.many drugs differing widely in chemical structure uncouple mitochondrial oxidative phosphorylation in vitro. this observation has led to the hypothesis that in vivo uncoupling is the basis of their pharmacological activity. serpasil, a parenteral preparation of reserpine, recently has been shown to uncouple oxidative phosphorylation in vervet monkey kidney mitochondria. although the drug exhibits some properties of a "classical" uncoupler, our studies show that it has a dual effect on energy con ...19836222736
the ultrastructural response to loading of the oral mucosa of the vervet monkey. 19836227734
a quantitative electron microscope study of desmosomes and hemi-desmosomes in vervet monkey oral mucosa. 19836230431
comparative effects of meal timing on circadian rhythms of plasma insulin and skin surface temperature in non-human primates.circadian rhythms of plasma immunoreactive insulin and skin surface temperature were demonstrated in a group of african green vervets. alteration in the timing of a single daily meal of fixed calorie content resulted in an acrophase shift of plasma immunoreactive insulin for the group of animals and in an acrophase shift of skin surface temperature in 7 or the 8 animals studied. the acrophase shift of skin surface temperature was considerably less then the shift of acrophase of plasma immunoreac ...19836347560
standardization of radiorenography in dehydrated and rehydrated primates under laboratory conditions.radiorenography with 99mtc-labelled diethylenetriaminepentacetic acid ( [99mtc]-dtpa) was performed on chacma baboons (papio ursinus) and vervet monkeys (cercopithecus pygerythus) to establish the effects of various states of hydration on the data obtained from the dtpa-renogram. the renogram parameters, which can be related to certain aspects of kidney function, varied significantly with the degree of hydration. it is therefore imperative for clinically directed animal research projects on the ...19836389879
the pathogenesis of trypanosomiasis of the cns. studies on parasitological and neurohistological findings in trypanosoma rhodesiense infected vervet monkeys.parasitological examinations of the cerebrospinal fluid of 20 vervet monkeys (cercopithecus aethiops), that had been infected with trypanosoma rhodesiense, revealed that the csf was regularly infested with trypanosomes in the early phase of the disease, at the earliest on the 13th day, in most of the animals in the 3rd or 4th week, after infection. follow-up examinations of the csf during the further course of the disease also regularly proved positive for trypanosomes. histological studies in t ...19836407189
vasoactive intestinal polypeptide (vip) as a putative neurotransmitter in penile erection.the localization of vasoactive intestinal polypeptide (vip) in the male genitourinary tract was investigated in the rabbit and man by means of radioimmunoassay and immunohistochemistry. in addition, the in vitro effect of vip upon penile smooth muscle from man, the vervet monkey, and the rabbit was investigated. significant concentrations of vip immunoreactivity were found in the human penis and all the organs of the rabbit genital tract apart from the testis. vip immunoreactive nerve fibres wer ...19836410140
metabolism of the serum amyloid a proteins (ssa) in high-density lipoproteins and chylomicrons of nonhuman primates (vervet monkey).serum amyloid protein (saa) has been reported to be an apoprotein of high-density lipoprotein (hdl), but little is known concerning its metabolism. in this study, aposaa was induced in nonhuman primate plasma hdl and thoracic duct lymph chylomicra by overnight chair restraint of the animals. there was a 3-6-fold increase in plasma hdl aposaa in chair-restrained animals when compared with caged (control) animals. lymph chylomicrons of chaired animals also contained significant amounts (approximat ...19836412556
the effect of splinting upon periodontal and pulpal healing after autotransplantation of mature and immature permanent incisors in monkeys.the effect of splinting upon periodontal and pulpal healing after autotransplantation of teeth with complete and incomplete root formation was studied in 16 green vervet monkeys (cercopithecus aethiops). 2 maxillary incisors were extracted in each monkey and autotransplanted to the contralateral socket. one of these teeth was stabilized with an acrylic splint for either 2 or 6 weeks, while the other incisor was non-splinted. the animals were sacrificed 8 weeks after autotransplantation and the a ...19836418671
cryopreservation of mature teeth before replantation in monkeys (i). effect of different cryoprotective agents and freezing devices.cryopreservation is clinically relevant in storage of teeth for transplantation or replantation. the effect of cryopreservation was studied by histometric analysis of 60 teeth replanted in 10 green vervet monkeys. the following cryopreserving agents were examined: 5% and 10% dimethylsulfoxide (dmso) and 10% glycerol. furthermore, 2 types of freezing method were compared: automatic biological freezing (cryoson) and a simplified freezing device of sperling. cryopreserved teeth were stored for 1 we ...19836425233
brotherly alliances help avoid inbreeding: patterns of inbreeding avoidance behavior in vervet monkeys has a profound influence on the social organization of neighboring groups. 198317741649
structural and functional organization of the suprapatella in two cercopithecines.gross and microscopic study of cercopithecus aethiops pygerythrus and papio cyanocephalus anubis shows that these cercopithecines have a quadriceps tendon the distal portion of which consists mostly of dense collagenous bundles with scattered fine elastic fibres most of which lie in the loose connective tissue planes within and around the tendon and around blood vessels. a distinct fibrovesicular structure, the suprapatella, lies within the tendon of the vastus intermedius above the pony patella ...19836854652
diet and dominance among female vervet monkeys (cercopithecus aethiops).behavioral observations of free-ranging female vervet monkeys (cercopithecus aethiops) suggest that priority of access to food enhances individual fitness. seventeen adult females living in two social groups were observed for 26 months in the samburu/isiolo game reserves, northern kenya. priority of access to feeding and sitting sites was associated with significant differences in diet and reproduction. food species distribution altered rank-related differences in diet. rank-related differences ...198331991946
brief report: circadian variation in insulin response in african green monkeys (cercopithecus aethiops).among a group of african green monkeys (cercopithecus aethiops), plasma insulin concentrations were greater following either intravenous (iv) glucose infusion or oral feeding at 0800 compared with iv glucose or oral feeding at 1700. glucose clearance rates after iv infusion were similar at the two test times. insulin/glucose ratios were greater following either iv glucose infusion or oral feeding at 0800 compared with 1700. these circadian variations in plasma insulin response are similar to rep ...198331986857
effect of chronic amphetamine administration on dopaminergic systems in the vervet brain: relationship to findings in the brains of schizophrenics. 19836131000
determinants of fecundity and reproductive success in captive vervet monkeys.between 1975 and 1983, adult female vervet monkeys (cercopithecus aethiops sabaeus) over 3.5 years of age, living in two undisturbed social groups in a captive colony in sepulveda, california, have averaged 1.0 births per female year with a mean interbirth interval of 10.7 months. increased fecundity did not result in decreased survival rates of offspring in this population. fecundity was influenced by the mother's age and dominance rank. the primary factor in the age-fecundity relationship was ...198432138459
operant conditioning of autogrooming in vervet monkeys: cercopithecus aethiops.vervet monkeys received food reinforcement contingent on autogrooming. experiment 1 reinforced grooming on a schedule of increasing intermittency and grooming increased in frequency and duration; with only pauses reinforced, grooming decreased in frequency and duration. experiment 2 demonstrated differentiation of operant autogrooming; in each session a different single form of grooming was reinforced (for example, grooming the tail only), and that form increased in frequency while other forms b ...198416812384
effect of trans-unsaturated fats on experimental atherosclerosis in vervet monkeys.vervet monkeys ( ceropithecus aethiops pygerethrus ) were placed on semipurified diets containing 14% fat of which 3.2 or 6.0% was present as trans-unsaturated fatty acid (t-fa). two groups were fed the high and low levels of t-fa for a year and two others were fed t-fa for 6 months and then returned to the control diet for 6 months more. one other group was fed the control diet for a year. the control diet contained 14% fat which was a mixture of 72% olive oil and 28% corn oil. there were no si ...19846426484
influence of root development on periodontal and pulpal healing after replantation of incisors in monkeys.the influence of root development on periodontal and pulpal healing after replantation was examined in 30 green vervet monkeys (cercopithecus aethiops) in which a total of 50 teeth were replanted. maxillary central incisors with different stages of root development (immature, young mature and mature root formation) were replanted with untreated pulps or after root canal treatment with gutta percha and kerr sealer. the extra-alveolar period in all groups was 18 min. the animals were sacrificed 8 ...19846434451
autotransplantation and replantation of tooth germs in monkeys. effect of damage to the dental follicle and position of transplant in the alveolus.the effect of damage to the follicle and of superficial positioning of tooth germs after replantation or autotransplantation was studied in green vervet monkeys. radiographs were taken immediately after surgery and 3, 6 and 9 months postoperatively, whereafter the animals were sacrificed. the tissue blocks were sectioned in step serial sections along a frontal plane and histologic and radiographic evaluation was made. tooth germs whose follicle was either damaged or removed showed no sign of eru ...19846434452
effects of water and saline irrigation during bone cutting on bone healing.the healing of standardized bony defects prepared in the mandibles of 24 vervet monkeys with a rotating bur uncooled, or cooled with saline or water, was studied. the experiment showed no difference in healing after 56 days irrespective of the coolant used or whether the bone was cut with or without a cooling agent.19846438006
pulpal response to a bis-acryl-plastic (protemp) temporary crown and bridge material.the pulpal response to protemp (espe gmbh) was compared to zinc oxide-eugenol, super syntrex (de trey) and protemp plus zinc oxide-eugenol liner in 144 vervet monkey (cercopithecus pygerythus) incisor teeth, according to ada specification no. 41. cellular displacement into dentinal tubules, superficial and deep inflammation were present only in the 3-day specimens in all materials. mean scores for the test material were lower than both negative and positive controls. in the 30-day specimens the ...19846440957
serotypic similarity and diversity of rotaviruses of mammalian and avian origin as studied by plaque-reduction neutralization.a total of 16 different strains of rotavirus derived from seven mammalian species (four each from human and porcine species, two each from equine and simian species, and one each from canine and bovine species) and two avian species (one each from turkeys and chickens) were examined in plaque-reduction neutralization tests. seven antigenically distinct serotypes were established on the basis of a greater than or equal to 20-fold difference between titers of homologous and heterologous reciprocal ...19846202807
cerebrospinal fluid measurements suggest precursor availability and sex are involved in the control of biogenic amine metabolism in a primate.biogenic amine precursors and metabolites were measured in cisternal cerebrospinal fluid from 83 female and 55 male vervet monkeys. the results indicate that mean rates of 5-hydroxytryptamine, dopamine, and noradrenaline metabolism in the brain are higher in females than in males. they also suggest that under physiological circumstances tryptophan availability is involved in the control of brain 5-hydroxytryptamine synthesis while tyrosine availability is involved in control of both dopamine and ...19846202838
social and environmental influences on blood serotonin concentrations in monkeys.dominant male adult vervet monkeys have whole-blood serotonin concentrations approximately twice those of subordinate adult males. we examined the effects of spontaneous and induced changes in social status, temporary isolation from the social group, and membership in single male groups on whole-blood serotonin concentrations. we found that in male vervet monkeys, elevated blood serotonin concentration is a state-dependent consequence of active occupation of the dominant male social position, an ...19846703857
grooming, alliances and reciprocal altruism in vervet monkeys.reciprocal altruism refers to the exchange of beneficial acts between individuals, in which the benefits to the recipient exceed the cost to the altruist. theory predicts that cooperation among unrelated animals can occur whenever individuals encounter each other regularly and are capable of adjusting their cooperative behaviour according to experience. although the potential for reciprocal altruism exists in many animal societies, most interactions occur between closely related individuals, and ...19846709060
[local dermatitis followed by pigmentation in green vervet monkeys].a group of 154 green vervets (cercopithecus aethiops) was studied from a clinical and pathological point of view. in 27 male and two female animals a skin lesion was noticed on genitals. physiological blue colour of these parts due to melanin cells in deep corium turned red at first; skin was smooth without itching and acute or subacute dermatitis was present in histology. later smooth skin got dark or blackened because of epidermal melanin pigmentation though melanocytes are lacking in normal e ...19846713561
the acoustic features of vervet monkey grunts.east african vervet monkeys give short (125 ms), harsh-sounding grunts to each other in a variety of social situations: when approaching a dominant or subordinate member of their group, when moving into a new area of their range, or upon seeing another group. although all these vocalizations sound similar to humans, field playback experiments have shown that the monkeys distinguish at least four different calls. acoustic analysis reveals that grunts have an aperiodic f0, at roughly 240 hz. most ...19846736426
experimental schistosoma mansoni infection in vervet monkeys (cercopithecus aethiops) in kenya: i. susceptibility to a primary infection.groups of five 3-kg kenyan monkeys, cercopithecus aethiops, were exposed individually to 150,600 or 1500 schistosoma mansoni cercariae per monkey. three monkeys died soon after the infections became patent and the survivors were autopsied 4 months after exposure. mortality and most haematological, parasitological and pathological sequelae of infection were dose-related, but not the white cell response or changes in the levels of serum proteins or fibrinogen. no gross liver fibrosis was seen. com ...19846747261
histological evaluation of quantitative scintigraphy of the salivary glands in a primate model.to assess the accuracy with which quantitative scintigraphy reflects the true extent of parenchymal losses in diseased salivary glands, the parotid glands of vervet monkeys were unilaterally subjected to experimental injury and studied by scintigraphy and histomorphometry. the glandular 99tcm pertechnetate uptake, relative to a standard dose, was expressed as the ratio of operated to unoperated sides. this was compared with the equivalent ratios of the weights of various salivary component tissu ...19846329975
growth and morphological characteristics of vervet monkey bone marrow-derived adherent cells.monkey bone marrow-derived adherent cells were maintained in culture for six months. phase contrast and scanning electron microscopy showed two cell shapes: fusiform and polygonal. no difference was observed in the cyto-chemical staining of the two shapes. both stained positively for alpha-napthyl acetate esterase, acid phosphatase, collagens i and iii, and lipids and negatively for peroxidase and factor viii antigen. a small proportion (1.5%) were alkaline phosphatase-positive. an average of 14 ...19846491392
lysosomal acid deoxyribonuclease from vervet monkey livers--i. purification and physico-chemical characterization.acid dnase from monkey liver lysosomes was purified to homogeneity by salt extraction of lysosomal membranes at ph 3.8; (nh4)2so4 fractionation; low salt precipitation; sp-c50 and g-150 sephadex chromatography; and polyacrylamide gel electrophoresis. the ph for optimum activity was dual in character with a labile optimum at ph 3.8 and a less active but stable one at ph 4.2. the estimated molecular weight was 40k and the pi was 4.4. inorganic ions such as ca2+, mg2+, mn2+ and so2-4 were more than ...19846530007
lysosomal acid deoxyribonuclease from vervet monkey livers--ii. enzymic properties.primate liver lysosomal acid dnase is an endonucleolytic enzyme. the enzyme has both 3'- and 5'-nucleotidohydrolase activities. the oligonucleotides produced by dnase are polymers mainly about 30 mononucleotides long. the arrhenius plot shows a discontinuity with a transition temperature at 47 degrees c, with an activation energy of 107 kj/mol below and 67 kj/mol above this temperature. the activation enthalpy is 104 kj/mol and the entropy -0.498 kj/mol/k. the enzyme is subject to substrate inhi ...19846530008
tooth transplantation with the periodontium intact: a histometric analysis.a method was devised, from a pilot study, for transplanting a root-treated tooth with an intact periodontium into a newly prepared socket to assess whether the prognosis for transplantation procedures could be improved. five male vervet monkeys were used for the definitive study. the mandibular central incisors were extracted from each monkey and the sockets were allowed to heal for 5 weeks. thereafter a window of gingiva overlying each of these healed receptor sites was removed and the sockets ...19846584035
rhodanese from cercopithecus aethiops (vervet monkey) liver. i. purification and some physical characteristics.rhodanese (thiosulphate sulphurtransferase , ec 2.8.1.1.) from cercopithecus aethiops (vervet monkey) liver has been isolated and purified by means of extraction, ammoniumsulphate and ph fractionation, anion-exchange chromatography, sephacryl s-300 gel chromatography and cation-exchange chromatography. a yield of about 10% pure enzyme with a specific activity of 242 u/mg protein corresponding to a purification factor of 523 was obtained. the enzyme was physically characterized and its homogeneit ...19846586594
rhodanese from cercopithecus aethiops (vervet monkey) liver. ii. aspects of enzyme kinetics and mechanism of action.initial velocity kinetic studies were undertaken and certain kinetic parameters ( kmsso2 -3 = 3.1 x 10(-3) m and vmax = 153.85 u/ml/min.) were determined and the mechanism identified as a ping-pong (double displacement) mechanism. competitive inhibition of rhodanese by both substrates, viz. thiosulphate and cyanide, provides additional evidence of ping-pong bi-bi mechanism for this transferase.19846586595
a comparison of three methods for titration of poliovirus vaccines.two methods for in vitro endpoint titration of poliovirus--the roller tube and the microtitration assay--were compared with each other and with the plaque assay, using secondary vervet monkey kidney cells and vero cells as indicators. the roller tube method is the most reliable under difficult working conditions, but is otherwise cumbersome and expensive. the microtitre method is the most economical and the plaque assay the most sensitive. by suspending freshly trypsinized indicator cells with t ...19846096387
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