Publications

effects on perceived air quality and symptoms of exposure to microbially produced metabolites and compounds emitted from damp building materials.	this work investigated perceived air quality and health effects from exposure to low to high levels of volatile organic compounds (vocs) emitted from damp building materials and a mixture of molds growing on the materials. a mixture of wallemia sebi, fusarium culmorum, penicillium chrysogenum, ulocladium botrytis, and aspergillus versicolor was inoculated on pine wood and particle board. in study 1, each of 27 participants took part in two exposure conditions, one with air from molds growing on ...	2009	19077173
mouse model of aspergillus and alternaria induced rhinosinusitis.	fungi are known to induce the production of chemical mediators from respiratory epithelial cells and have been increasingly recognized as important pathogens in sinusitis. however, the exact role of fungi in the pathogenesis of rhinosinusitis has not been clearly established. this study was performed to improve our understanding of the role of fungi in the pathogenesis of rhinosinusitis by developing an animal model of fungus induced rhinosinusitis.	2009	19084360
treatment of fungal bioaerosols by a high-temperature, short-time process in a continuous-flow system.	airborne fungi, termed fungal bioaerosols, have received attention due to the association with public health problems and the effects on living organisms in nature. there are growing concerns that fungal bioaerosols are relevant to the occurrence of allergies, opportunistic diseases in hospitals, and outbreaks of plant diseases. the search for ways of preventing and curing the harmful effects of fungal bioaerosols has created a high demand for the study and development of an efficient method of ...	2009	19201954
cottoquinazoline a and cotteslosins a and b, metabolites from an australian marine-derived strain of aspergillus versicolor.	an australian marine-derived isolate of aspergillus versicolor (mst-mf495) yielded the known fungal metabolites sterigmatocystin, violaceol i, violaceol ii, diorcinol, (-)-cyclopenol, and viridicatol, along with a new alkaloid, cottoquinazoline a (1), and two new cyclopentapeptides, cotteslosins a (2) and b (3). structures for 1-3 and the known compounds were determined by spectroscopic analysis. the absolute configurations of 1-3 were addressed by chemical degradation and application of the c(3 ...	2009	19245260
determination of microbial volatile organic compounds (mvocs) by passive sampling onto charcoal sorbents.	passive sampling combined with gc-ms was applied for the detection of microbial volatile organic compounds (mvocs) emitted by mould cultures. the fungi species penicillium expansum, penicillium chrysogenum, penicillium brevicompactum, aspergillus fumigatus, aspergillus versicolor, aspergillus niger, and cladosporium cladosporoides were cultivated on dichloran glycerol agar. the emitted volatiles were collected by charcoal-based passive diffusion monitors during the first four weeks of growth. se ...	2009	19289243
brevianamide j, a new indole alkaloid dimer from fungus aspergillus versicolor.	brevianamide j (1), a new indole alkaloid dimer, was isolated together with four new diketopiperazine alkaloids (brevianamide k-n, 2-5) from the solid-state fermented culture of aspergillus versicolor. their structures were elucidated on the basis of spectral data. x-ray crystallographic analysis confirmed the structures of 1 and 4.	2009	19627104
patterns of susceptibility of aspergillus isolates recovered from patients enrolled in the transplant-associated infection surveillance network.	we analyzed antifungal susceptibilities of 274 clinical aspergillus isolates from transplant recipients with proven or probable invasive aspergillosis collected as part of the transplant-associated infection surveillance network (transnet) and examined the relationship between mic and mortality at 6 or 12 weeks. antifungal susceptibility testing was performed by the clinical and laboratory standards institute (clsi) m38-a2 broth dilution method for amphotericin b (amb), itraconazole (itr), voric ...	2009	19692558
effect of glycosylation on the biochemical properties of beta-xylosidases from aspergillus versicolor.	aspergillus versicolor grown on xylan or xylose produces two beta-xylosidases with differences in biochemical properties and degree of glycosylation. we investigated the alterations in the biochemical properties of these beta-xylosidases after deglycosylation with endo-h or pngase f. after deglycosylation, both enzymes migrated faster in page or sds-page exhibiting the same r(f). temperature optimum of xylan-induced and xylose-induced beta-xylosidases was 45 degrees c and 40 degrees c, respectiv ...	2009	19557344
use of zero-valent iron nanoparticles in inactivating microbes.	nanoscale zero-valent iron (nzvi) particles were investigated in inactivating gram-positive bacillus subtilis var. niger and gram-negative pseudomonas fluorescens bacteria, and the fungus aspergillus versicolor. nzvi particles were synthesized using nabh(4) and fe(no(3))(3).9h(2)o, and the microbial suspensions were subjected to the treatments of nzvi particle suspensions with concentrations of 0.1, 1 and 10mg/ml for 5min. field emission scanning electron microscope (fe-sem) was used to characte ...	2009	19783027
jem spotlight: fungi, mycotoxins and microbial volatile organic compounds in mouldy interiors from water-damaged buildings.	concerns have been raised about exposure to mycotoxin producing fungi and the microbial volatile organic compounds (mvocs) they produce in indoor environments. therefore, the presence of fungi and mycotoxins was investigated in 99 samples (air, dust, wallpaper, mycelium or silicone) collected in the mouldy interiors of seven water-damaged buildings. in addition, volatile organic compounds (vocs) were sampled. the mycotoxins were analysed by liquid chromatography-tandem mass spectrometry (lc-ms/m ...	2009	19809708
effective bioremoval of reactive dye and heavy metals by aspergillus versicolor.	in this study, bioaccumulation of heavy metal and dye by aspergillus versicolor was investigated. optimum ph values of the maximum heavy metal bioaccumulation was found as 6 for 50mg/l cr(vi), ni(ii) and 5 for cu(ii) ions with the 99.89%, 30.05% and 29.06% removal yield, respectively. the bioremoval of the dye up to 800 mg/l at ph 5 and 6 was investigated and 27.15% and 28.95% removal rates were measured respectively. the presence of cr(vi) with dye, decreased the uptake yield for both pollutant ...	2010	19773159
bioactive metabolites from the sponge-derived fungus aspergillus versicolor.	as part of an ongoing search for bioactive metabolites from the fungus aspergillus versicolor derived from a marine sponge petrosia sp., an aromatic polyketide derivative (1), two xanthones (2 and 3), and five anthraquinones (4-8) were isolated by bioactivity-guided fractionation. the gross structures were determined based on the nmr and ms spectroscopic data, and the absolute configurations were defined by comparison of optical rotation data with those of reported. compounds 2, 4, 5, and 7 exhi ...	2010	20195823
wild-type minimum effective concentration distributions and epidemiologic cutoff values for caspofungin and aspergillus spp. as determined by clinical and laboratory standards institute broth microdilution methods.	antifungal susceptibility testing of aspergillus spp. against caspofungin has been standardized by the clinical and laboratory standards institute (clsi). recent studies have documented breakthrough infections with aspergillus spp. for which the minimum effective concentration (mec) for caspofungin ranged from 0.25 to 8 microg/ml. we tested a collection of 1590 clinical isolates of aspergillus spp. (188 aspergillus flavus, 1187 aspergillus fumigatus, 114 aspergillus niger, 71 aspergillus terreus ...	2010	20207095
distribution and identification of airborne fungi in railway stations in tokyo, japan.	the current study was performed to (1) understand the distribution of airborne fungi culturable on dichloran-glycerol agar (dg18) media over a one-year monitoring period, (2) identify the types of airborne fungi collected, and (3) compare and contrast under- and above-ground spaces, in two railway stations in tokyo, japan.	2010	20299760
onychomycosis caused by aspergillus versicolor.	we report a case of onychomycosis caused by aspergillus versicolor in a 66-year-old female patient. the infection was characterised clinically by yellowish pigmentation of the nail plate and mild nail bed hyperkeratosis of the first left toe. all other nails were normal. three direct microscopical examinations of nail samples revealed the presence of hyaline hyphae as well as conidiophores. pure colonies of a. versicolor were found in three cultures. the patient was successfully treated with ora ...	2010	19422523
comparison of techniques to examine the diversity of fungi in adult patients with cystic fibrosis.	this study compares conventional and molecular techniques for the detection of fungi in 77 adult cystic fibrosis (cf) patients. three different methods were investigated, i.e., (1) conventional microbiological culture (including yeasts and filamentous fungi), (2) mycological culture with cf-derived fungal specific culture media, and (3) non-culture and direct dna extraction from patient sputa. fungi isolated from environmental air samples of the cf unit were compared to fungi in sputa from cf pa ...	2010	19672783
adsorption profile of lead on aspergillus versicolor: a mechanistic probing.	the adsorption of lead on aspergillus versicolor biomass (avb) has been investigated in aqueous solution with special reference to binding mechanism in order to explore the possibilities of the biomass to address environmental pollution. avb, being the most potent of all the fungal biomasses tested, has been successfully employed for reducing the lead content of the effluents of battery industries to permissible limit (1.0 mg l(-1)) before discharging into waterbodies. the results establish that ...	2010	21159429
[organic dust at workplaces: measurement of pyrogenic activity].	organic dust is composed of numerous components. exposed people may have health problems. respiratory tract complaints may occur at workplaces like those in agriculture or in the waste industry. therefore methods that determine the composition and activity of dust components are important. they help in the performance of risk estimations and could accompany intervention studies. the aim of our study was to establish a whole blood assay using cryo-preserved blood for characterisation of the pyrog ...	2010	20533171
characterization of phenolic content, in vitro biological activity, and pesticide loads of extracts from white grape skins from organic and conventional cultivars.	grape skin extracts of riesling vitis vinifera l. grapes from conventionally or organically managed cultivars were compared on the basis of their phenolic content, antioxidant capacity, antimicrobial and antimutagenic properties and pesticide loads. promising results on their biological properties suggest that those extracts would be valuable as food preservatives. the antioxidant capacity of conventional extracts was significantly higher, according to the higher content in catechin, epicatechin ...	2010	20870004
sterigmatocystins from the deep-sea-derived fungus aspergillus versicolor.	three new sterigmatocystin derivatives, oxisterigmatocystin a (1), oxisterigmatocystin b (2) and oxisterigmatocystin c (3), together with one known compound, 5-methoxysterigmatocystin (4), were isolated from the deep-sea-derived fungus aspergillus versicolor. the structures of the new compounds were elucidated by spectroscopic methods. the cytotoxicities of compounds 1-4 were evaluated against the a-549 and hl-60 cell lines. compound 4 exhibited moderate cytotoxicities against the a-549 and hl-6 ...	2010	21119680
apoptosis-inducing effect of diketopiperazine disulfides produced by aspergillus sp. kmd 901 isolated from marine sediment on hct116 colon cancer cell lines.	research is to identify the bioactive secondary metabolites produced by aspergillus sp. kmd 901 isolated from marine sediment and to assess their apoptosis-inducing effects.	2010	21122037
other fungi causing onychomycosis.	nondermatophyte onychomycosis account for 2% to 12% of all nail fungal infections and can be caused by a wide range of fungi, mainly scopulariopsis brevicaulis, aspergillus versicolor, a. flavus, a. niger, a. fumigatus, fusarium solani, f. oxysporum and scytalidium spp. among the predisposing factors are footwear, hyperhidrosis, local trauma, peripheral circulatory disease, and immunosuppression. these nondermatophyte fungi lack the keratinolytic capacity of dermatophytes, but they still can inf ...	2010	20347658
use of epidemiological cutoff values to examine 9-year trends in susceptibility of aspergillus species to the triazoles.	in the absence of clinical breakpoints, epidemiological cutoff values (ecvs) have been established to distinguish wild-type (wt) isolates of aspergillus spp. from those that may harbor resistance mutations. recently, the clsi has developed ecvs for triazoles (itraconazole, posaconazole, and voriconazole) and common aspergillus species. we applied the triazole ecvs to 1,789 aspergillus isolates collected from 63 centers worldwide from 2001 to 2009 to determine the frequency of non-wt strains of e ...	2010	21123534
cerebral mycosis: 7-year retrospective series in a tertiary center.	this study focuses on the epidemiology, clinical manifestations, risk factors, diagnosis and outcome of all cases of central nervous system (cns) fungal infections in a tertiary center. medical records of 18 patients of culture-proven cns fungal infections were retrospectively reviewed from 2000 to 2007, including 12 isolated from the cerebrospinal fluid (csf) and seven from tissue biopsy. patient demographic data included 10 males and eight females. the mean age was 55 years (range: 24-89 years ...	2010	19845862
dna damage and dna damage responses in thp-1 monocytes after exposure to spores of either stachybotrys chartarum or aspergillus versicolor or to t-2 toxin.	we have characterized cell death in thp-1 cells after exposure to heat-treated spores from satratoxin g-producing stachybotrys chartarum isolate ibt 9631, atranone-producing s. chartarum isolate ibt 9634, and sterigmatocystin-producing aspergillus versicolor isolate ibt 3781, as well as the trichothecenes t-2 and satratoxin g. spores induced cell death within 3-6 h, with stachybotrys appearing most potent. ibt 9631 induced both apoptosis and necrosis, while ibt 9634 and ibt 3781 induced mostly n ...	2010	20150440
the mycobiota of three dry-cured meat products from slovenia.	the surface mycobiota of three types of slovenian dry-cured meat products were isolated from a total of 75 items of product that were sampled periodically during the drying/ripening stage of processing. the predominant filamentous fungal genus isolated was penicillium. eurotium spp., aspergillus versicolor and cladosporium spp. were isolated from only two of the products. eight penicillium species were identified. penicillium nordicum was recovered frequently. penicillium nalgiovense was recover ...	2010	21356440
inflammatory cytokine gene expression in thp-1 cells exposed to stachybotrys chartarum and aspergillus versicolor.	very little is known about the mechanisms that occur in human cells upon exposure to fungi as well as their mycotoxins. a better understanding of toxin-regulated gene expression would be helpful to identify safe levels of exposure and could eventually be the basis for establishing guidelines for remediation scenarios following a water intrusion event. in this research, cytokine mrna expression patterns were investigated in the human monocytic thp-1 cell line exposed to fungal extracts of various ...	2011	21384497
characterization of the 41kda allergen asp v 13, a subtilisin-like serine protease from aspergillus versicolor.	aspergillus versicolor is common on moldy building materials. asp v 13, the principal allergen is produced by strains collected from across canada. in this paper, we report a 1833bp asp v 13 open reading frame predicted to encode a protein of 403 amino acids in length with three introns. a blast search of asp v 13, a phylogenic tree calculation and alignment with its homologous proteins from other species indicated that asp v 13 is a secretory, subtilisin-like serine protease widely distributed ...	2011	21632114
quantification of the aspergillus versicolor allergen in house dust.	aspergillus versicolor, a fungus commonly found on damp building materials, produces the allergen, asp v 13. here we report a sensitive asp v 13 capture elisa for a. versicolor spores and spore- and mycelial fragments in house dust samples. the method is based on a double polyclonal capture elsia. the detection limits for asp v 13 antigen and a. versicolor spores without dust were 2.44pg and 12ng (ca. 110 spores). detection limits for asp v 13 and a. versicolor spores in sieved house dust sample ...	2011	21763696
notoamide e: biosynthetic incorporation into notoamides c and d in cultures of aspergillus versicolor nrrl 35600.	notoamide e, a short-lived secondary metabolite, has been proposed as a biosynthetic intermediate to several advanced metabolites isolated from aspergillus versicolor. in order to verify the role of this indole alkaloid along the biosynthetic pathway, synthetic doubly (13)c-labeled notoamide e was fed to aspergillus versicolor. analysis of the metabolites showed significant incorporation of notoamide e into the natural products notoamides c and d.	2011	22140279
[fungal nail infections - an update : part 2 - from the causative agent to diagnosis - conventional and molecular procedures.]	trichophyton (t.) rubrum is the most frequently isolated dermatophyte in onychomycosis, both in germany and worldwide. t. interdigitale (formerly t. mentagrophytes var. interdigitale) follows in second place. a further however rarely isolated dermatophyte in onychomycosis is epidermophyton floccosum. candida parapsilosis, candida guilliermondii, and candida albicans, followed by trichosporon spp. are the most important yeasts which are found in onychomycosis. the molds most often responsible inc ...	2011	22037818
[activity of antioxidant system of aspergillus versicolor with radioadaptive properties under conditions of exposure to radiation].	melanin pigments were revealed for the first time in aspergillus versicolor strains. ionizing irradiation practically did not influence melanin synthesis in a. versicolor strains with radioadaptive properties and stimulated its synthesis in the control strain, which did not show such properties. high level of superoxide dismutase activity (from 100 up to 720 u/mg of protein) was revealed in the investigated strains. the irradiation in exponential phase of growth did not practically influence or ...	2011	22164697
collection efficiencies of an electrostatic sampler with superhydrophobic surface for fungal bioaerosols.	we recently developed an electrostatic precipitator with superhydrophobic surface (epss), which collects particles into a 10- to 40-μl water droplet allowing achievement of very high concentration rates (defined as the ratio of particle concentration in the collection liquid vs. the airborne particle concentration per time unit) when sampling airborne bacteria. here, we analyzed the performance of this sampler when collecting three commonly found fungal spores--cladosporium cladosporioides, peni ...	2011	21204982
new quinazolinone alkaloids within rare amino acid residue from coral-associated fungus, aspergillus versicolor lcj-5-4.	cottoquinazoline d (3), a new alkaloid with a 1-aminocyclopropane-1-carboxylic acid residue rarely discovered in nature, was isolated and identified together with two new quinazolinone alkaloids, cottoquinazolines b (1) and c (2), from coral-associated fungus aspergillus versicolor lcj-5-4. their structures including absolute configurations were elucidated based on spectroscopic methods, x-ray single crystal diffraction analysis, and chemical methods. a possible biogenetic pathway for them was p ...	2011	21271733
fungal dna, allergens, mycotoxins and associations with asthmatic symptoms among pupils in schools from johor bahru, malaysia.	while there is a large variation of prevalence of asthma symptoms worldwide, what we do know is that it is on the rise in developing countries. however, there are few studies on allergens, moulds and mycotoxin exposure in schools in tropical countries. the aims were to measure selected fungal dna, furry pet allergens and mycotoxins in dust samples from schools in malaysia and to study associations with pupils' respiratory health effects. eight secondary schools and 32 classrooms in johor bahru, ...	2011	21457336
biological active metabolite cyclo (l-trp-l-phe) produced by south china sea sponge holoxea sp. associated fungus aspergillus versicolor strain ts08.	sponge-associated fungi represent the single most prolific source of novel natural products from marine fungi. cyclo (l-trp-l-phe) exhibits biological functions such as plant growth regulation, moderate cytotoxicity and thus has the application potential in pharmaceutical and agricultural biotechnologies. in this study, a fungal strain ts08 was isolated from sponge holoxea sp. in the south china sea and identified as a. versicolor according to its 18s rrna gene and morphological, physiological, ...	2011	20809226
biosynthetic studies of the notoamides: isotopic synthesis of stephacidin a and incorporation into notoamide b and sclerotiamide.	the advanced natural product stephacidin a is proposed as a biosynthetic precursor to notoamide b in various aspergillus species. doubly (13)c-labeled racemic stephacidin a was synthesized and fed to cultures of the terrestrial-derived fungus, aspergillus versicolor nrrl 35600, and the marine-derived fungus, aspergillus sp. mf297-2. analysis of the metabolites revealed enantiospecific incorporation of intact (-)-stephacidin a into (+)-notoamide b in aspergillus versicolor and (+)-stephacidin a i ...	2011	21714564
Composition and antimicrobial activity of Seseli globiferum essential oil.	The essential oil from aerial parts of Seseli globiferum Vis. obtained by hydrodistillation with Clevenger-type apparatus was analyzed by GC-MS. Twenty-eight compounds were identified, representing 99.4% of the total oil. The main components of the oil were sabinene (38.0%), alpha-pinene (21.2%) and beta-phellandrene (13.5%). The microbial growth inhibitory properties of the isolated essential oil were determined using the broth microdilution method against seven bacterial species: Salmonella ty ...	2011	21922927
studies on the biosynthesis of the notoamides: synthesis of an isotopomer of 6-hydroxydeoxybrevianamide e and biosynthetic incorporation into notoamide j.	6-hydroxydeoxybrevianamide e is proposed as a biosynthetic precursor to several advanced metabolites isolated from both marine-derived aspergillus sp. and a terrestrial-derived aspergillus versicolor. to verify the role of this reverse-prenylated indole alkaloid as an intermediate along the biosynthetic pathway, [13c]2-[15n]-6-hydroxydeoxybrevianamide e was synthesized and fed to aspergillus versicolor. analysis of the metabolites showed complete incorporation of the intermediate into the natura ...	2011	21504234
associations between fungal species and water damaged building materials.	fungal growth in damp or water damaged buildings worldwide is an increasing problem, which has adverse effects on both the occupants and the buildings. air sampling alone in moldy buildings does not reveal the full diversity of fungal species growing on building materials. one aim of this study was to estimate the qualitative and quantitative diversity of fungi growing on damp or water damaged building materials. another was to determine if associations exist between the most commonly found fung ...	2011	21531835
[influence of different types of ionizing radiation on fatty acid profiles of microscopic fungi, showing radioadaptive properties].	the fatty acid profiles of strains of dark-pigmented (melanin-containing) species cladosporium cladosporioides and hormoconis resinae, and light-pigmented aspergillus versicolor and paecilomyces lilacinus, showing radioadaptive properties in comparison with control strains of the same species, which did not have such properties and the influence on them of two (121sn; 137cs) types of ionizing radiation have been studied. it was established that the most important fatty acids were hexadecanoic ac ...	2011	21598656
cytotoxicity of aspergillus fungi isolated from hospital environment.	the majority of mycotoxins produced by aspergillus fungi are immunosuppressive agents, and their cytotoxicity may impair defense mechanisms in humans. the objective of the study was evaluation of the cytotoxicity of fungi isolated from an environment where inpatients with impaired immunity were present. the materials comprised 57 fungal strains: aspergillus fumigatus, aspergillus niger: aspergillus ochraceus, aspergillus flavus, aspergillus versicolor and aspergillus ustus isolated from hospital ...	2011	21630575
Fungal DNA in hotel rooms in Europe and Asia--associations with latitude, precipitation, building data, room characteristics and hotel ranking.	There is little information on the indoor environment in hotels. Analysis of fungal DNA by quantitative PCR (qPCR) is a new method which can detect general and specific sequences. Dust was collected through swab sampling of door frames in 69 hotel rooms in 20 countries in Europe and Asia (2007-2009). Five sequences were detected by qPCR: total fungal DNA, Aspergillus and Penicillium DNA (Asp/Pen DNA), Aspergillus versicolor (A. versicolor DNA), Stachybotrys chartarum (S. chartarum DNA) and Strep ...	2011	21897974
Total viable molds and fungal DNA in classrooms and association with respiratory health and pulmonary function of European schoolchildren.	To cite this article: Simoni M, Cai G-H, Norback D, Annesi-Maesano I, Lavaud F, Sigsgaard T, Wieslander G, Nystad W, Canciani M, Viegi G, Sestini P. Total viable molds and fungal DNA in classrooms and association with respiratory health and pulmonary function of European schoolchildren. Pediatr Allergy Immunol 2011: 22: 843-852. ABSTRACT: Indoor molds are associated with adverse respiratory effects in children. Although schools are important exposure sources of molds, objective measurements were ...	2011	22122789
invasive pulmonary aspergillosis caused by aspergillus versicolor in a patient on mechanical ventilation.	aspergillus spp. often colonise the respiratory tract of critically ill patients in intensive care units and subsequently cause invasive disease. the risk of developing invasive disease is more in immunocompromised patients. here we report a case of fatal invasive pulmonary aspergillosis caused by aspergillus versicolor in a post-operative patient on mechanical ventilation, who did not respond to intravenous itraconazole. we then discuss the challenges involved in the accurate diagnosis of this ...	2011	23386878
gamma irradiation of cultural artifacts for disinfection using monte carlo simulations.	in this study, it has been investigated the disinfection of korean cultural artifacts by gamma irradiation, simulating the absorbed dose distribution on the object with the monte carlo methodology. fungal contamination was identified on two traditional korean agricultural tools, hongdukkae and holtae, which had been stored in a museum. nine primary species were identified from these items: bjerkandera adusta, dothideomycetes sp., penicillium sp., cladosporium tenuissimum, aspergillus versicolor, ...	2012	22940410
pcr detection of aflatoxin producing fungi and its limitations.	unlike bacterial toxins that are primarily peptides and are therefore encoded by a single gene, fungal toxins such as the aflatoxins are multi-ring structures and therefore require a sequence of structural genes for their biological synthesis. there is therefore no specific pcr for any one of the four biologically produced aflatoxins. unfortunately, the structural genes presently in use for pcr detection of aflatoxin producing fungi are also involved in the synthesis of other fungal toxins such ...	2012	22445201
identification of volatile markers for indoor fungal growth and chemotaxonomic classification of aspergillus species.	microbial volatile organic compounds (mvocs) were collected in water-damaged buildings to evaluate their use as possible indicators of indoor fungal growth. fungal species isolated from contaminated buildings were screened for mvoc production on malt extract agar by means of headspace solid-phase microextraction followed by gas chromatography-mass spectrometry (gc-ms) analysis. some sesquiterpenes, specifically derived from fungal growth, were detected in the sampled environments and the corresp ...	2012	22954337
[farmer's lung antigens in germany].	recent studies suggest that besides the long-known farmer's lung antigen sources saccharopolyspora rectivirgula (micropolyspora faeni), thermoactinomyces vulgaris, and aspergillus fumigatus, additionally the mold absidia (lichtheimia) corymbifera as well as the bacteria erwinia herbicola (pantoea agglomerans) and streptomyces albus may cause farmer's lung in germany. in this study the sera of 64 farmers with a suspicion of farmer's lung were examined for the following further antigens: wallemia ...	2012	22477566
effects of sterigmatocystin on tnf-α, il-6 and il-12 expression in murine peripheral blood mononuclear cells and peritoneal macrophages in vivo.	sterigmatocystin (st) is a toxic metabolite mainly produced by the fungi aspergillus nidulans and aspergillus versicolor. st is considered a potent carcinogen, mutagen and teratogen. however, over the past few years, it has been demonstrated that it is less acutely toxic to rodents in vivo. in this study, we evaluated the putative effects of st on the expression of tumor necrosis factor-α (tnf-α), interleukin (il)-6 and il-12 at mrna levels in murine peripheral blood mononuclear cells (mpbmcs) a ...	2012	22344519
aspergillus section versicolores: nine new species and multilocus dna sequence based phylogeny.	β-tubulin, calmodulin, internal transcribed spacer and partial lsu-rdna, rna polymerase 2, dna replication licensing factor mcm7, and pre-rrna processing protein tsr1 were amplified and sequenced from numerous isolates belonging to aspergillus sect. versicolor. the isolates were analyzed phylogenetically using the concordance model to establish species boundaries. aspergillus austroafricanus, a. creber, a. cvjetkovicii, a. fructus, a. jensenii, a. puulaauensis, a. subversicolor, a. tennesseensis ...	2012	23155501
Aspergillus versicolor, a New Causative Agent of Canine Disseminated Aspergillosis.	Disseminated aspergillosis in dogs has been associated with Aspergillus terreus or A. deflectus infection. We report a case of disseminated A. versicolor infection presenting as diskospondylitis, osteomyelitis, and pyelonephritis. The diagnosis was made based on clinical, radiographic, and pathological findings. The etiologic agent was identified by fungal culture and internal transcribed spacer (ITS) ribosomal DNA (rDNA) sequencing. This is the first description of canine aspergillosis caused b ...	2012	22031699
determination of inflammatory responses to aspergillus versicolor and endotoxin with human cryo-preserved blood as a suitable tool.	the aim of this study was to characterize the mediator release in the whole blood assay induced by stimulation with an extract of the indoor mold a. versicolor. in addition, the effect of concomitant stimulation with e. coli endotoxin and a. versicolor, and the involvement of the relevant toll-like receptors were investigated. the stimulation of cryo-preserved whole blood with 400pg/ml e. coli endotoxin induced a significant il-1β release (976±133pg/ml), whereas, none of the tested a. versicolor ...	2012	23273580
bioactive anthraquinones from endophytic fungus aspergillus versicolor isolated from red sea algae.	the marine fungus aspergillus versicolor was isolated from the inner tissue of the red sea green alga halimeda opuntia. the fungus was identified by its morphology and 18s rdna. cultivation of this fungal strain led to a new metabolite named isorhodoptilometrin-1-methyl ether (1) along with the known compounds emodin (2), 1-methyl emodin (3), evariquinone (4), 7-hydroxyemodin 6,8-methyl ether (5), siderin (6), arugosin c (7), and variculanol (8). the structures were elucidated on the basis of nm ...	2012	23139125
anthraquinone derivatives produced by marine-derived fungus aspergillus versicolor en-7.	the new anthraquinone derivative, 6,8-di-o-methylaverantin (1), together with six known congeners (2-7), were characterized from a culture extract of the marine algous fungus, aspergillus versicolor en-7. their structures were elucidated by spectroscopic methods. a bioassay showed compounds 1, 2 and 5 to have weak inhibition against escherichia coli, while compound 5 also displayed weak inhibition against staphylococcus aureus.	2012	22972319
brevianamides with antitubercular potential from a marine-derived isolate of aspergillus versicolor.	an aspergillus versicolor isolated from sediment collected from the bohai sea, china, yielded the new dimeric diketopiperazine brevianamide s (1), together with three new monomeric cometabolites, brevianamides t (2), u (3), and v (4). structures were determined by detailed spectroscopic analysis. brevianamide s exhibited selective antibacterial activity against bacille calmette-guérin (bcg), suggestive of a new mechanism of action that could inform the development of next-generation antitubercul ...	2012	22963079
dectin-1 and il-17a suppress murine asthma induced by aspergillus versicolor but not cladosporium cladosporioides due to differences in β-glucan surface exposure.	there is considerable evidence supporting a role for mold exposure in the pathogenesis and expression of childhood asthma. aspergillus versicolor and cladosporium cladosporioides are common molds that have been implicated in asthma. in a model of mold-induced asthma, mice were repeatedly exposed to either a. versicolor or c. cladosporioides spores. the two molds induced distinct phenotypes, and this effect was observed in both balb/c and c57bl/6 strains. c. cladosporioides induced robust airway ...	2012	22962686
bioremoval of textile dyes with different chemical structures by aspergillus versicolor in molasses medium.	bioremoval of 17 dyes with different chemical structures by aspergillus versicolor was detected in this study. maxilon red grl (mr-grl), everdirect fast black vsf (efb-vsf) and brillant blue r (bb-r) were removed better by fungal mycelia. optimum ph values were found as 6 for all three dyes. in further experiments in the highest dye concentrations tested in this study, 58.3, 100 and 49% removal yields and 14.8, 12.6, 9.0 q(m) values were found for mr-grl, efb-vsf and bb-r, respectively. chemical ...	2012	22949249
a new sesquiterpene from an endophytic aspergillus versicolor strain.	a new sesquiterpene, albican-1,14-diol (1), and seven known compounds, including sterigmatocystin (2), 3-hydroxy-5-(hydroxymethyl)-4-(4'-hydroxyphenoxy) pyrrolidin-2-one (3), (1h-indol-3-yl) oxoacetamide (4), indole-3-carboxylic acid (5), indole-3-acetic acid (6), indole-3-carboxaldehyde (7), and volemolide (8), were isolated from the cultures of aspergillus versicolor, an endophytic fungus isolated from the marine green alga codium fragile. the structure of 1 was elucidated by 1d, 2d nmr and ma ...	2012	22908554
isotherm and kinetic models and cell surface analysis for determination of the mechanism of metal sorption by aspergillus versicolor.	the isolate aspergillus versicolor was obtained from an estuary, which is exposed to metal contamination. it was found to have a good metal tolerance and sorption capacity. further studies revealed that the rate of metal removal from solution is very rapid in the first 5-10 min, and is favoured by a ph of 6.0. the biosorption data obtained was explained by the freundlich adsorption isotherm model and followed a pseudo-second order kinetics reaction. the fungus showed a higher accumulation of fat ...	2012	22806158
effect of two aerosolization methods on the release of fungal propagules from a contaminated agar surface.	the effect of perpendicular and swirling aerozolization methods on the release of fungal fragments and spores from agar surface was studied. three fungal species (aspergillus versicolor, cladosporium cladosporioides, penicillium chrysogenum) were selected for the tests as they commonly occur indoors, create different hyphae structure when they grow on surfaces, and have different spore shapes, aerodynamic sizes, and formation mechanisms. as the tested surface, petri dishes filled with malt extra ...	2012	22742802
cytotoxicity and genotoxicity of versicolorins and 5-methoxysterigmatocystin in a549 cells.	aspergillus versicolor and a. flavus are primary colonizers in damp dwellings, and they produce sterigmatocystin (st) and aflatoxin b1 (afb(1)), respectively. these hepatotoxic and carcinogenic mycotoxins and their precursors and derivates possess a furofuran ring, which has proven responsible for their toxicity. the aim of this study was to investigate the cytotoxicity and genotoxicity of versicolorin a (ver a) and versicolorin b (ver b), as the furofuran precursors of aflatoxins and st, and of ...	2012	22648070
effects of onion (allium cepa l.) and garlic (allium sativum l.) essential oils on the aspergillus versicolor growth and sterigmatocystin production.	in the present study the effects of individual and combined essential oils (eos) extracted from onion (allium cepa l.) bulb and garlic (allium sativum l.) clove on the growth of aspergillus versicolor and sterigmatocystin (stc) production were investigated. the eos obtained by hydrodistillation were analyzed by gc/ms. twenty one compounds were identified in onion eo. the major components were: dimethyl-trisulfide (16.64%), methyl-propyl-trisulfide (14.21%), dietil-1,2,4-tritiolan (3r,5s-, 3s,5s- ...	2012	22497489
microbiological evaluation of ten french archives and link to occupational symptoms.	fungi that damage documents in archives may harm workers' health, depending on which mold species are inhaled, the concentrations of fungal species inhaled, and individual factors. our aim was to identify and quantify fungi in archives and to investigate possible links with the symptoms experienced by workers. ten french archives were sampled using an air impactor and electrostatic dust collectors. allergies and general symptoms felt by 144 workers were reported using a self-report questionnaire ...	2012	22429323
secondary metabolites from an algicolous aspergillus versicolor strain.	two new compounds, asperversin a (1) and 9ξ-o-2(2,3-dimethylbut-3-enyl)brevianamide q (2), and nine known compounds, brevianamide k (3), brevianamide m (4), aversin (5), 6,8-di-o-methylnidurufin (6), 6,8-di-o-methylaverufin (7), 6-o-methylaverufin (8), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (9), ergosta-7,22-diene-3β,5α,6β-triol (10), and 6β-methoxyergosta-7,22-diene-3β,5α-diol (11), were obtained from the culture of aspergillus versicolor, an endophytic fungus isolated from the marine brown alga ...	2012	22363226
remediation of mould damaged building materials--efficiency of a broad spectrum of treatments.	we compared the efficiency of some commercially available products and methods used for remediation of mould-contaminated building materials. samples of gypsum board and pinewood were artificially contaminated with toxin-producing isolates of stachybotrys chartarum and aspergillus versicolor, respectively, then, ten different remediation treatments were applied according to the manufacturers' instructions. microbial and chemical analyses of the infested materials were carried out both immediatel ...	2012	22286589
comparison of dna extraction methodologies used for assessing fungal diversity via its sequencing.	traditional methods of assessing fungal exposure have been confounded by a number of limiting variables. the recent utilization of molecular methods such as internal transcribed spacer (its) sequencing of ribosomal rna genes has provided improved insight into the diversity of fungal bioaerosols in indoor, outdoor and occupational environments. however, its analyses may also be confounded by a number of methodological limitations. in this study, we have optimized this technology for use in occupa ...	2012	22230933
occupational exposure to aflatoxin b1 in swine production and possible contamination sources.	although the adverse health consequences of ingestion of food contaminated with aflatoxin b1 (afb1) are known, relatively few studies are available on the adverse effects of exposure in occupational settings. taking this into consideration, our study was developed aiming to elucidate the possible effects of occupational exposure to afb1 in portuguese swine production facilities using a specific biomarker to assess exposure to afb1. in total, 28 workers participated in this study, providing blood ...	2013	24156697
[the effect of low radiation doses on the growth of aspergillus versicolor and paecilomyces lilacinus].	peculiarities of growth of the strains of two species of microscopic fungi aspergillus versicolor and paecilomyces lilacinus were analyzed under exposure to chronic irradiation. it was shown that the rate of radial growth increased nonuniformly in the range of doses from 0 to 250 mgy but with maximums at a certain dose of radiation. it was shown that the absorbed dose of radiation to 2 gy did not influence the survival of investigated strains in comparison with the control ones without irradiati ...	2013	24006782
identification of a brevianamide f reverse prenyltransferase brept from aspergillus versicolor with a broad substrate specificity towards tryptophan-containing cyclic dipeptides.	a putative brevianamide f reverse prenyltransferase gene brept was amplified from aspergillus versicolor nrrl573 by using primers deduced from its orthologue notf in aspergillus sp. mf297-2 and overexpressed in escherichia coli. the soluble his-tagged protein brept was purified to near homogeneity and assayed with tryptophan-containing cyclic dipeptides in the presence of dimethylallyl diphosphate. brept showed much higher flexibility towards its aromatic substrates than notf and accepted all of ...	2013	22660767
furry pet allergens, fungal dna and microbial volatile organic compounds (mvocs) in the commercial aircraft cabin environment.	there has been concern about the cabin environment in commercial aircraft. we measured cat, dog and horse allergens and fungal dna in cabin dust and microbial volatile organic compounds (mvocs) in cabin air. samples were collected from two european airline companies, one with cabins having textile seats (tsc) and the other with cabins having leather seats (lsc), 9 airplanes from each company. dust was vacuumed from seats and floors in the flight deck and different parts of the cabin. cat (fel d1 ...	2013	23644832
fungal contamination in swine: a potential occupational health threat.	poor air quality in a pig-confinement building may potentially place farmers at higher health risk than other workers for exposure to airborne pollutants that may reach infectious levels. the aim of this study was to assess worker exposure to fungi in indoor environments in portuguese swine buildings. air samples from 7 swine farms were collected at a flow rate of 140 l/min, at 1 m height, onto malt extract agar supplemented with chloramphenicol (mea). surfaces samples of the same indoor sites w ...	2013	23514069
structural elucidation of an extracellular polysaccharide produced by the marine fungus aspergillus versicolor.	a homogenous extracellular polysaccharide, designated awp, was isolated from the fermented liquid of the marine fungus aspergillus versicolor from the coral cladiella sp. and purified by anion-exchange and size-exclusion chromatography (sec). chemical and spectroscopic analyses, including one- and two-dimensional nuclear magnetic resonance (1d and 2d nmr) spectroscopy showed that awp consisted of glucose and mannose in a molar ratio of 8.6:1.0, and its average molecular weight was estimated to b ...	2013	23499086
synthesis and bioconversions of notoamide t: a biosynthetic precursor to stephacidin a and notoamide b.	in an effort to further elucidate the biogenesis of the stephacidin and notoamide families of natural products, notoamide t has been identified as the likely precursor to stephacidin a. the total synthesis of notoamide t is described along with it is c-6-epimer, 6-epi-notoamide t. the chemical conversion of stephacidin a to notoamide t by reductive ring opening is described as well as the oxidative conversion of notoamide t to stephacidin a. furthermore, [(13)c](2)-notoamide t was synthesized an ...	2013	23249380
studies on the biosynthesis of chetomin: enantiospecific synthesis of a putative, late-stage biosynthetic intermediate.	the enantiospecific synthesis of desthiochetomin, a putative biosynthetic intermediate of the epidithiodioxopiperazine natural product chetomin, is described. a diastereoselective n-alkylation was employed to form the key c3-n1' bond of the heterodimeric indoline core, followed by peptide coupling and dioxopiperazine cyclization with the requisite n-methyl amino acids. a related sarcosine-derived dioxopiperazine was prepared in the same manner. the first proposed biosynthesis of chetomin is also ...	2013	24489414
ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.	in rooms with moisture damage, the indoor air can be enriched with microorganisms causing a variety of symptoms. due to the highly diverse composition of bioaerosols and the multiple effects on humans, an assessment of the health risk is not sufficiently possible. the aim of this study was to characterize the features of innate immunity using blood from subjects exposed to moisture damage compared to control subjects living in houses without visible moisture damage. we investigated the expressio ...	2013	24340055
diorcinols b-e, new prenylated diphenyl ethers from the marine-derived fungus aspergillus versicolor zln-60.	four new prenylated diphenyl ethers (1-4), diorcinols b-e, together with one known diorcinol (5), were obtained from the marine-derived fungus aspergillus versicolor. their structures were established on the basis of chemical and spectroscopic data. the absolute configurations of compounds 1 and 2 were determined by mosher's ester and specific rotation analysis. their cytotoxicities were evaluated using a-549, hela, bel-7402 and k562 cell lines. compound 3 exhibited moderate cytotoxicities again ...	2013	23677033
a new immunoassay to quantify fungal antigens from the indoor mould aspergillus versicolor.	aspergillus versicolor is among the most commonly found moulds in moisture-damaged buildings and can be associated with adverse health effects in humans. this paper reports the development, validation and application of an enzyme immunoassay to quantify a. versicolor antigens. a sandwich elisa was developed using polyclonal antibodies that recognize a broad range of a. versicolor proteins present in fungal spores and in mycelia fragments. to validate the new method, a. versicolor antigens were q ...	2013	23674292
aspeverin, a new alkaloid from an algicolous strain of aspergillus versicolor.	a novel carbamate- and cyano-containing alkaloid, aspeverin (1), was isolated from the culture of an algicolous aspergillus versicolor strain (dl-29). the structure and absolute configuration were unambiguously identified by nmr, ir, ecd, and mass spectrometric methods as well as quantum chemical calculations. 1 exhibited potent bioactivities against some marine-derived organisms.	2013	23650962
antimicrobial and antioxidant activities of alcoholic extracts of rumex dentatus l.	in-vitro antimicrobial and antioxidant activities of various concentrations ranging from 150 to 500 μg/ml of alcoholic (methanol and ethanol) extracts of rumex dentatus were analyzed on different clinical bacterial strains (shigella flexneri, klebsiella pneumoniae, escherichia coli, pseudomonas aeruginosa, salmonella typhimurium, staphylococcus aureus) and fungal strains (aspergillus versicolor, aspergillus flavus, acremonium spp., penicillium dimorphosporum, candida albicans, candida kruesie, c ...	2013	23415966
biochemical and immunological analysis of mould skin prick test solution: current status of standardization.	sensitization prevalence to moulds reached from less than 10% in the general population to more than 25% in atopic and/or asthmatic subjects. to diagnose ige-mediated mould sensitization, skin prick test (spt) and specific ige (sige) measurement are recommended. however, concordance of spt and sige results is often less than 50% and standardization of the extracts is required to achieve reliable test results.	2013	24152161
in vitro antifungal activity of silver nanoparticles against ocular pathogenic filamentous fungi.	fungal keratitis is emerging as a major cause of vision loss in a developing country such as china because of higher incidence and the unavailability of effective antifungals. it is urgent to explore broad-spectrum antifungals to effectively suppress ocular fungal pathogens, and to develop new antifungal eye drops to combat this vision-threatening infection. the aim of this study is to investigate the antifungal activity of silver nanoparticles (nano-ag) in comparison with that of natamycin agai ...	2013	23410063
fungal food choices of dermatophagoides farinae affect indoor fungi selection and dispersal.	house dust mite (hdm) feces and molds are the main allergens involved in allergic asthma. differences exist between the housing fungal biome of allergic patients and standard or unhealthy housing. house dust mite (hdm) feed off spores and transport them on their bodies, but do they have fungal food preferences? we observed dermatophagoïdes farinae in vitro with 16 mold menus and repeated the experiment 10 times. this observation led us to define alternaria alternata, cladosporium sphaerospermum, ...	2013	22774849
molecular and microscopic analysis of the gut contents of abundant rove beetle species (coleoptera, staphylinidae) in the boreal balsam fir forest of quebec, canada.	experimental research on beetle responses to removal of logging residues following clearcut harvesting in the boreal balsam fir forest of quebec revealed several abundant rove beetle (staphylinidae) species potentially important for long-term monitoring. to understand the trophic affiliations of these species in forest ecosystems, it was necessary to analyze their gut contents. we used microscopic and molecular (dna) methods to identify the gut contents of the following rove beetles: atheta caps ...	2013	24294095
selection of enhanced antimicrobial activity posing lactic acid bacteria characterised by (gtg)5-pcr fingerprinting.	the aim of the study was a detail evaluation of genetic diversity among the lactic acid bacteria (lab) strains having an advantage of a starter culture in order to select genotypically diverse strains with enhanced antimicrobial effect on some harmfull and pathogenic microorganisms. antimicrobial activity of lab was performed by the agar well diffusion method and was examined against the reference strains and foodborne isolates of bacillus cereus, listeria monocytogenes, escherichia coli, staphy ...	2014	26139877
allergic sensitization in canadian chronic rhinosinusitis patients.	chronic rhinosinusitis (crs) is a societal burden and cause of morbidity in canada; however, the prevalence of allergic sensitization in canadian crs patients has remained poorly characterized.	2014	24666655
aspergillus flavus contamination in two portuguese wastewater treatment plants.	filamentous fungi from genus aspergillus were previously detected in wastewater treatment plants (wwtp) as being aspergillus flavus (a. flavus), an important toxigenic fungus producing aflatoxins. this study aimed to determine occupational exposure adverse effects due to fungal contamination produced by a. flavus complex in two portuguese wwtp using conventional and molecular methodologies. air samples from two wwtp were collected at 1 m height through impaction method. surface samples were coll ...	2014	25072712
concentration of bioaerosols in composting plants using different quantification methods.	bioaerosols (organic dusts) containing viable and non-viable microorganisms and their metabolic products can lead to adverse health effects in exposed workers. standard quantification methods of airborne microorganisms are mainly based on cultivation, which often underestimates the microbial burden. the aim of the study was to determine the microbial load in german composting plants with different, mainly cultivation-independent, methods. second purpose was to evaluate which working areas are as ...	2014	24759376
quantification of c. globosum spores in house dust samples.	chaetomium globosum is one of the most common fungi that grows in damp buildings and occurs in agricultural and forestry workplaces. using sera from atopic patients, we characterized and purified an extracellular chitosanase (chg47) from c. globosum that is antigenic to humans. the study reports the production of monoclonal antibodies to the protein. three capture elisas were developed for chg47 for detection of spores and spore and mycelial fragments in dust samples using different mono- and po ...	2014	25292122
evaluation of biotechnological potentials of some industrial fungi in economical lipid accumulation and biofuel production as a field of use.	considering the vast number of scientific reports on various potential uses of fungi, there was an attempt to select the best lipid producer of some fungi at optimized conditions (aspergillus versicolor, rhizopus oryzae, rhizopus arrhizus, tramates versicolor). the aim was to offer new fields of use to the industries already culturing and using such materials. aspergillus versicolor mycelia were found to be accumulating the highest amount of lipids. experiments to improve lipid accumulation and ...	2014	24320234
three new sterigmatocystin analogues from marine-derived fungus aspergillus versicolor mf359.	during the systematic screening of active compounds from marine-derived fungi, the extract of a strain of aspergillus versicolor mf359 isolated from a marine sponge of hymeniacidon perleve was identified for detailed chemical investigation. three new secondary metabolites, named hemiacetal sterigmatocystin (1), acyl-hemiacetal sterigmatocystin (2), and 5-methoxydihydrosterigmatocystin (3), together with a known compound, aversin (4), were characterized. 1 represents a first structure of sterigma ...	2014	24458562
cytotoxic polyphenols from a sponge-associated fungus aspergillus versicolor hmp-48.	a new dibenzo[1,4]dioxin 1, and two new prenylated diphenyl ethers, 2 and 3, together with six known compounds, 4-9, were isolated from a sponge-associated fungus aspergillus versicolor hmp-f48 by bioactivity-guided fractionation. their structures were elucidated by 1d- and 2d-nmr, and ms analyses. the compounds showed potent cell growth inhibitory activities against hl-60 cell line.	2014	24443433
[trichophyton rubrum onychomycosis with secondary aspergillus versicolor infection in a 12-year-old girl: successful topical therapy with terbinafine-urea ointment].	a 12-year-old with a functional circulatory disturbance had toe nail onychomycosis caused by trichophyton rubrum. there were no other underlying diseases.	2014	24817253
metabolites from aspergillus versicolor, an endolichenic fungus from the lichen lobaria retigera.	three new anthraquinone derivatives (1-3) and one new artifact (4) were isolated, along with six known anthraquinone derivatives (5-10) and three xanthones (11-13), from a culture of an endolichenic fungus, aspergillus versicolor, that was isolated from the lichen lobaria retigera. the structures of these substances were determined on the basis of 1d and 2d (cosy, hmqc, and hmbc) nmr and ms analyses. the substances 1-4 were also tested for their cytotoxic activity.	2014	24815583
nucleoside derivatives from the marine-derived fungus aspergillus versicolor.	four nucleoside derivatives (1-4) were isolated from the fungus aspergillus versicolor derived from the gorgonian dichotella gemmacea collected in the south china sea. their structures were elucidated by comprehensive spectroscopic method of nmr and ms analysis. all isolated metabolites were evaluated for their cytotoxicity, antibacterial activity and lethality towards brine shrimp artemia salina. compounds 1/2 exhibited selective antibacterial activity against staphylococcus epidermidis with an ...	2014	24670197
psychrophilins e-h and versicotide c, cyclic peptides from the marine-derived fungus aspergillus versicolor zln-60.	four new cyclic peptides, psychrophilins e-h (1-4), possessing a rare amide linkage between the carboxylic acid in anthranilic acid (ata) and the nitrogen from an indole moiety, along with a new ata-containing hexapeptide, versicotide c (5), were obtained from the culture of the marine-derived fungus aspergillus versicolor zln-60. the structures, including absolute configurations, were elucidated by a combination of hresims, nmr, x-ray crystallography, tddft ecd calculations, and marfey's method ...	2014	25246036
aspergillines a-e, highly oxygenated hexacyclic indole-tetrahydrofuran-tetramic acid derivatives from aspergillus versicolor.	aspergillines a-e (1-5) are highly oxygenated cyclopiazonic acid (cpa)-derived alkaloids bearing a rigid and sterically congested hexacyclic indole-tetrahydrofuran-tetramate scaffold, isolated from the endophytic fungus aspergillus vesicolor. apergillines a-c represent a new subclass of cpa-derived alkaloids, and aspergillines b and e possess a butanoic acid methyl ester moiety. the structures, including absolute configuration, were elucidated by interpretation of the nmr, x-ray crystallographic ...	2014	25226561
biodegradation and utilization of 4-n-nonylphenol by aspergillus versicolor as a sole carbon and energy source.	4-n-nonylphenol (4-n-np) is an environmental pollutant with endocrine-disrupting activities that is formed during the degradation of nonylphenol polyethoxylates, which are widely used as surfactants. utilization of 4-n-np by the filamentous fungus aspergillus versicolor as the sole carbon and energy source was investigated. by means of gas chromatography-mass spectrometry, we showed that in the absence of any carbon source other than 4-n-np in the medium, a. versicolor completely removed the xen ...	2014	25222932
aspergilloma caused by aspergillus versicolor.		2014	25222316
total synthesis of aspeverin via an iodine(iii)-mediated oxidative cyclization.	the first total synthesis of aspeverin, a prenylated indole alkaloid isolated from aspergillus versicolor in 2013, is described. key steps utilized to assemble the core structure of the target include a highly diastereoselective diels-alder reaction, a curtius rearrangement, and a unique strategy for installation of the geminal dimethyl group. a novel iodine(iii)-initiated cyclization was then used to install the bicyclic urethane linkage distinctive to the natural product.	2014	25171639