Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| molecular detection of rickettsia felis and candidatus rickettsia asemboensis in fleas from human habitats, asembo, kenya. | the flea-borne rickettsioses murine typhus (rickettsia typhi) and flea-borne spotted fever (fbsf) (rickettsia felis) are febrile diseases distributed among humans worldwide. murine typhus has been known to be endemic to kenya since the 1950s, but fbsf was only recently documented in northeastern (2010) and western (2012) kenya. to characterize the potential exposure of humans in kenya to flea-borne rickettsioses, a total of 330 fleas (134 pools) including 5 species (xenopsylla cheopis, ctenoceph ... | 2013 | 23675818 |
| dissemination of bloodmeal acquired rickettsia felis in cat fleas, ctenocephalides felis. | cat fleas, ctenocephalides felis, are known biological vectors for rickettsia felis. rickettsial transmission can be vertical via transovarial transmission within a flea population, as well as horizontal between fleas through a bloodmeal. the previously undescribed infection kinetics of bloodmeal-acquired r. felis in cat fleas provides insight into the r. felis-flea interaction. | 2013 | 23705666 |
| genomic diversification in strains of rickettsia felis isolated from different arthropods. | rickettsia felis (alphaproteobacteria: rickettsiales) is the causative agent of an emerging flea-borne rickettsiosis with worldwide occurrence. originally described from the cat flea, ctenocephalides felis, recent reports have identified r. felis from other flea species, as well as other insects and ticks. this diverse host range for r. felis may indicate an underlying genetic variability associated with host-specific strains. accordingly, to determine a potential genetic basis for host speciali ... | 2014 | 25477419 |
| candidatus 'rickettsia senegalensis' in cat fleas in senegal. | epidemiological studies of rickettsia felis and related bacteria are very important, because the natural cycle of this important infection has not yet been established. the recent emergence of r. felis-associated febrile diseases in west and east africa demands insightful epidemiological studies of the vectors and reservoirs of this bacterium in africa. twenty-nine cat fleas, ctenocephalides felis, were tested for the presence of rickettsiae, including r. felis, bartonellae, and borreliae, with ... | 2014 | 25755888 |
| first report of rickettsia felis in china. | rickettsia felis is a recently described flea-borne spotted fever group rickettsia that is an emerging human pathogen. although there is information on the organism from around the world, there is no information on the organism in china. | 2014 | 25510419 |
| first report of babesia gibsoni in central america and survey for vector-borne infections in dogs from nicaragua. | although many vector-borne diseases are important causes of morbidity and mortality in dogs in tropical areas and potential zoonoses, there is little information on these conditions in central america. | 2014 | 24667065 |
| the role of cats in the eco-epidemiology of spotted fever group diseases. | mediterranean spotted fever (msf), whose etiological agent is r. conorii, is one of the oldest described vector-borne infectious diseases. although it is endemic in the mediterranean area, clinical cases have also been reported in other regions. r. massiliae-bar29 is related to msf cases. this strain is distributed worldwide. r. conorii and r. massiliae-bar29 are transmitted by ticks. dogs are considered the sentinel of r. conorii infection. cats could also be involved in their transmission. ric ... | 2014 | 25084969 |
| molecular detection of rickettsia felis and bartonella henselae in dog and cat fleas in central oromia, ethiopia. | fleas are important vectors of several rickettsia and bartonella spp. that cause emerging zoonotic diseases worldwide. in this study, 303 fleas collected from domestic dogs and cats in ethiopia and identified morphologically as ctenocephalides felis felis, c. canis, pulex irritans, and echidnophaga gallinacea were tested for rickettsia and bartonella dna by using molecular methods. rickettsia felis was detected in 21% of fleas, primarily c. felis, with a similar prevalence in fleas from dogs and ... | 2014 | 24445204 |
| serosurvey of rickettsia typhi and rickettsia felis in hiv-infected patients. | consistent with the effects of hiv on cell-mediated immunity, an increased susceptibility to intracellular microorganisms has been observed. rickettsiae are obligate intracellular microorganisms. the aim of this study was to examine rickettsia typhi and rickettsia felis infections in hiv+ population. sera of 341 hiv+ patients were evaluated by indirect immunofluorescent assay. age, sex, residential locality, risk behavior, stage according to criteria of the center for disease control and prevent ... | 2014 | 24467705 |
| detection of rickettsia felis, rickettsia typhi, bartonella species and yersinia pestis in fleas (siphonaptera) from africa. | little is known about the presence/absence and prevalence of rickettsia spp, bartonella spp. and yersinia pestis in domestic and urban flea populations in tropical and subtropical african countries. | 2014 | 25299702 |
| two human cases of rickettsia felis infection, thailand. | 2014 | 25272251 | |
| rickettsia felis and changing paradigms about pathogenic rickettsiae. | 2014 | 25271441 | |
| a molecular survey of rickettsia felis in fleas from cats and dogs in sicily (southern italy). | rickettsia felis, the agent of flea-borne spotted fever, has a cosmopolitan distribution. its pathogenic role in humans has been demonstrated through molecular and serologic tests in several cases. the cat flea (ctenocephalides felis) is considered the main reservoir and the biological vector. the aim of this study was to assess the presence and occurrence of r. felis in fleas collected from dogs and cats in various sites of palermo (sicily). between august and october 2012, 134 fleas were colle ... | 2014 | 25203839 |
| molecular identification of pathogenic bacteria in eschars from acute febrile patients, senegal. | fever caused by rickettsia felis was recently shown to play an important role in infectious diseases morbidity in sub-saharan africa. we collected 68 cotton swabs from fever-associated eschars in four different regions of senegal. in 5 of 68 eschar samples (7.4%), we have identified dna from r. felis. in 49 of 68 eschar samples (72.1%), we have identified dna from staphylococcus aureus. in 35 of 68 eschar samples (51.5%), we have identified dna from streptococcus pyogenes, and in 4 of 68 eschar ... | 2014 | 25200258 |
| rickettsia felis infections and comorbid conditions, laos, 2003-2011. | 2014 | 25061919 | |
| development and validation of a quantitative real-time polymerase chain reaction assay specific for the detection of rickettsia felis and not rickettsia felis-like organisms. | human infections with rickettsia felis have been reported worldwide. recent studies have revealed the presence of many closely related but unique rickettsiae, referred to as rickettsia felis-like organisms (rflo), identified in various arthropods. due to the recent discovery of the lack of specificity of earlier r. felis-specific assays, there has become a need to develop a new generation of r. felis-specific molecular assays that will differentiate r. felis not only from other rickettsiae but m ... | 2014 | 24918658 |
| rickettsia felis in ctenocephalides felis felis from five geographic regions of brazil. | this study evaluated rickettsial infection in 701 ctenocephalides felis felis fleas that were collected from dogs and cats in 31 municipalities, encompassing all regions and major biomes of brazil. a total of 268 (38.2%) fleas from 30 municipalities were polymerase chain reaction (pcr) positive for the rickettsial glta gene. the pcr products from 44 fleas, consisting of at least 1 pcr-positive flea from each of 30 municipalities, generated dna sequences identical to rickettsia felis. rickettsial ... | 2014 | 24778194 |
| human spotted fever group rickettsioses are underappreciated in southern taiwan, particularly for the species closely-related to rickettsia felis. | despite increased identification of spotted fever group rickettsioses (sfgr) in animals and arthropods, human sfgr are poorly characterized in taiwan. | 2014 | 24755560 |
| growth of rickettsia felis in drosophila melanogaster s2 cells. | rickettsia felis is an obligate, intracellular, gram-negative bacterium and a member of the transitional group rickettsiae. this bacterium has been shown to grow in vitro in amphibian, tick, and mosquito cell lines. here, we present data to show the growth of r. felis strain lsu in drosophila melanogaster s2 cells, an embryonic, hemocytic cell line with phagocytic properties. r. felis lsu was isolated from ixodes scapularis e6 (ise6) cells and used to infect s2 cells, grown at 25°c. by 19 days p ... | 2014 | 24528095 |
| rickettsia lusitaniae sp. nov. isolated from the soft tick ornithodoros erraticus (acarina: argasidae). | in this study a novel rickettsia from the spotted fever group, isolated from ornithodoros erraticus soft ticks collected from pigpens in the south of portugal, is described. after initial screening revealed rickettsia-positive ticks, isolation attempts were then performed. successful isolates were achieved by shell-vial technique using vero e6 cells at 28°c. molecular characterization of the isolate was performed based on analysis of five rickettsial genes glta, ompa, ompb, sca1 and htr with the ... | 2014 | 24513450 |
| bell's palsy and sudden deafness associated with rickettsia spp. infection in sweden. a retrospective and prospective serological survey including pcr findings. | sixty patients with facial palsy and 67 with sudden deafness were retrospectively or prospectively examined for serological evidence of rickettsial infection; in six cases where cerebrospinal fluid was available, patients were also examined for presence of rickettsial dna. | 2014 | 23790098 |
| transmission potential of rickettsia felis infection by anopheles gambiae mosquitoes. | a growing number of recent reports have implicated rickettsia felis as a human pathogen, paralleling the increasing detection of r. felis in arthropod hosts across the globe, primarily in fleas. here anopheles gambiae mosquitoes, the primary malarial vectors in sub-saharan africa, were fed with either blood meal infected with r. felis or infected cellular media administered in membrane feeding systems. in addition, a group of mosquitoes was fed on r. felis-infected balb/c mice. the acquisition a ... | 2015 | 26056256 |
| rickettsia rickettsii and rickettsia felis infection in rhipicephalus sanguineus ticks and ctenocephalides felis fleas co-existing in a small city in yucatan, mexico. | 2015 | 26611982 | |
| reply to slesak et al.: so much about rickettsia felis infection to be discovered. | 2015 | 26598651 | |
| prevalence of rickettsia and bartonella species in spanish cats and their fleas. | the aim of this study was to determine the prevalence of bartonella henselae, rickettsia felis, and rickettsia typhi in fleas and companion cats (serum and claws) and to assess their presence as a function of host, host habitat, and level of parasitism. eighty-nine serum and claw samples and 90 flea pools were collected. cat sera were assayed by ifa for bartonella henselae and rickettssia species igg antibodies. conventional pcrs were performed on dna extracted from nails and fleas collected fro ... | 2015 | 26611956 |
| rickettsia species in fleas collected from small mammals in slovakia. | epidemiological and epizootiological studies of rickettsia felis and other rickettsia spp. are very important, because their natural cycle has not yet been established completely. in total, 315 fleas (siphonaptera) of 11 species of ceratophyllidae, hystrichopsyllidae and leptopsyllidae families were tested for the presence of rickettsia species and coxiella burnetii with conventional and specific quantitative real-time pcr assays. fleas were collected from five rodent hosts (myodes glareolus, ap ... | 2015 | 26346455 |
| shell-vial culture and real-time pcr applied to rickettsia typhi and rickettsia felis detection. | murine typhus is a zoonosis transmitted by fleas, whose etiological agent is rickettsia typhi. rickettsia felis infection can produces similar symptoms. both are intracellular microorganisms. therefore, their diagnosis is difficult and their infections can be misdiagnosed. early diagnosis prevents severity and inappropriate treatment regimens. serology can't be applied during the early stages of infection because it requires seroconversion. shell-vial (sv) culture assay is a powerful tool to det ... | 2015 | 26289162 |
| rickettsia felis infection among humans, bangladesh, 2012-2013. | 2015 | 26196587 | |
| first molecular detection of rickettsia felis-like organism in eulaelaps stabularis from the changbai mountain area of china. | in 557 mites collected from rodents in the changbai mountain area, 3 pools of eulaelaps stabularis from apodemus peninsulae and apodemus agrarius showed a positive result by pcr amplifications of both the citrate synthase encoding gene (glta) and outer membrane protein b encoding gene (ompb) of rickettsia spp. sequence analysis indicated that both glta and ompb shared the high similarity (99%) to rickettsia felis . the data presented in this paper extend the knowledge on the geographic distribut ... | 2015 | 26016589 |
| integrated morphological and molecular identification of cat fleas (ctenocephalides felis) and dog fleas (ctenocephalides canis) vectoring rickettsia felis in central europe. | fleas of the genus ctenocephalides are the most common ectoparasites infesting dogs and cats world-wide. the species ctenocephalides felis and ctenocephalides canis are competent vectors for zoonotic pathogens such as rickettsia felis and bartonella spp. improved knowledge on the diversity and phylogenetics of fleas is important for understanding flea-borne pathogen transmission cycles. fleas infesting privately owned dogs and cats from the czech republic (n=97) and romania (n=66) were subjected ... | 2015 | 25899079 |
| isolation of candidatus rickettsia asemboensis from ctenocephalides fleas. | candidatus rickettsia asemboensis was identified molecularly in fleas collected in 2009 from asembo, kenya. multilocus sequence typing using the 17-kd antigen gene, rrs, glta, ompa, ompb, and sca4 demonstrated that candidatus r. asemboensis is closely related to rickettsia felis but distinct enough to be considered for separate species classification. following this molecular characterization of candidatus r. asemboensis, the in vitro cultivation of this bacterium was then performed. we used cte ... | 2015 | 25897814 |
| a case of rickettsia felis infection imported from nepal. | rickettsia felis is an emerging spotted fever group pathogen that may be responsible for potentially life-threatening infections. a cosmopolitan distribution has been postulated though most human cases were observed in africa and the americas. we report an imported case from nepal that occurred in an italian tourist who presented with a 1-week history of fever, headache, nausea, vomiting, and a mild maculopapular rash 14 days after return. | 2015 | 25884911 |
| evidence for a specific host-endosymbiont relationship between 'rickettsia sp. genotype rf2125' and ctenocephalides felis orientis infesting dogs in india. | fleas of the genus ctenocephalides serve as vectors for a number of rickettsial zoonoses, including rickettsia felis. there are currently no published reports of the presence and distribution of r. felis in india, however, the ubiquitous distribution of its vector ctenocephalides felis, makes it possible that the pathogen is endemic to the region. this study investigates the occurrence of rickettsia spp. infection in various subspecies of c. felis infesting dogs from urban areas of mumbai, delhi ... | 2015 | 25884425 |
| molecular detection of fastidious and common bacteria as well as plasmodium spp. in febrile and afebrile children in franceville, gabon. | malaria was considered as the main cause of fever in africa. however, with the roll back malaria initiative, the causes of fever in africa may change. this study aimed to evaluate the prevalence of bacteria and plasmodium spp. in febrile and afebrile (controls) children from franceville, gabon. about 793 blood samples from febrile children and 100 from controls were analyzed using polymerase chain reaction (pcr) coupled with sequencing. plasmodium spp. was the microorganism most detected in febr ... | 2015 | 25802432 |
| novel evidence suggests that a 'rickettsia felis-like' organism is an endosymbiont of the desert flea, xenopsylla ramesis. | fleas are acknowledged vectors and reservoirs of various bacteria that present a wide range of pathogenicity. in this study, fleas collected from wild rodents from the negev desert in southern israel were tested for rickettsiadna by targeting the 16s rrna (rrs) gene. thirty-eight xenopsylla ramesis, 91 synosternus cleopatrae and 15 leptopsylla flea pools (a total of 568 fleas) were screened. rickettsiadna was detected in 100% of the x. ramesis and in one s. cleopatrae flea pools. none of l. algi ... | 2015 | 25677805 |
| rickettsia and bartonella species in fleas from reunion island. | rickettsia felis, rickettsia typhi, and bartonella dna was detected by molecular tools in 12% of rattus rattus fleas (xenopsylla species) collected from reunion island. one-third of the infested commensal rodents captured during 1 year carried at least one infected flea. as clinical signs of these zoonoses are non-specific, they are often misdiagnosed. | 2015 | 25646263 |
| detection of rickettsia felis in wild mammals from three municipalities in yucatan, mexico. | the aim of this study was to provide information of the occurrence of rickettsia felis in wild mammals from three municipalities in yucatan, mexico. the reactivity of rodent serum to rickettsia antigens was detected in 80.9% (17 of 21) samples using immunofluorescence assay. polymerase chain reaction identified rickettsial dna in spleens of 43.5% (10 of 23) rodents and 57.1% (4 of 7) opossums. the identification of the rickettsial dna was confirmed as r. felis by restriction fragment length poly ... | 2015 | 25537628 |
| whole-genome sequence of "candidatus rickettsia asemboensis" strain nmrcii, isolated from fleas of western kenya. | herein we present the draft genome sequence and annotation of "candidatus rickettsia asemboensis" strain nmrcii. "ca. rickettsia asemboensis" is phylogenetically related to but distinct from the flea-borne spotted fever pathogen rickettsia felis. "ca. rickettsia asemboensis" was initially identified in and subsequently isolated from ctenocephalides cat and dog fleas from kenya. | 2015 | 25767219 |
| flea-borne rickettsioses and rickettsiae. | rickettsia typhi and rickettsia felis are flea-borne rickettsiae that are distributed throughout the world. this mini-review outlines the ecology and epidemiology of flea-borne rickettsioses; highlights important clinical, diagnostic, and therapeutic considerations; and discusses areas of uncertainty regarding rickettsia felis and other rickettsiae harbored by fleas. | 2016 | 27799640 |
| molecular detection of zoonotic rickettsiae and anaplasma spp. in domestic dogs and their ectoparasites in bushbuckridge, south africa. | members of the order rickettsiales are small, obligate intracellular bacteria that are vector-borne and can cause mild to fatal diseases in humans worldwide. there is little information on the zoonotic rickettsial pathogens that may be harbored by dogs from rural localities in south africa. to characterize rickettsial pathogens infecting dogs, we screened 141 blood samples, 103 ticks, and 43 fleas collected from domestic dogs in bushbuckridge municipality, mpumalanga province of south africa, be ... | 2016 | 26974185 |
| vector-borne pathogens in dogs and red foxes from the federal state of brandenburg, germany. | dirofilaria repens is endemic in eastern and southern european regions but was recently found in germany in dogs, mosquitoes and one human patient. since some of the positive dog and mosquito samples were collected in brandenburg, it was aimed to systematically assess the prevalence of d. repens and other canine vector-borne pathogens in brandenburg. dog owners also received a questionnaire and were asked to provide more information about the dogs including travel history. in total, 1023 dog blo ... | 2016 | 27270389 |
| molecular evidence of vector-borne pathogens in dogs and cats and their ectoparasites in algiers, algeria. | in algeria, only limited information is currently available on the prevalence of emergent canine and feline vector-borne diseases. the aim of the present work was to detect by qpcr vector-associated bacteria in stray dogs and cats and their ectoparasites from algiers. 18/117 (15.38%) dogs and 2/107 (1.87%) cats were positive for at least one vector-borne agent. coxiella burnetii and bartonella henselae were identified in 1/117 (0.85%) dog individually. ehrlichia canis dna was detected in 17/117 ... | 2016 | 27012917 |
| transmission mechanisms of an emerging insect-borne rickettsial pathogen. | vector-borne pathogens must overcome arthropod infection and escape barriers (e.g. midgut and salivary glands) during the extrinsic incubation period (eip) before subsequent transmission to another host. this particular timespan is undetermined for the etiological agent of flea-borne spotted fever (rickettsia felis). artificial acquisition of r. felis by blood-feeding cat fleas revealed dissemination to the salivary glands after seven days; however, this length of time is inconsistent with co-fe ... | 2016 | 27117813 |
| rickettsia vini n. sp. (rickettsiaceae) infecting the tick ixodes arboricola (acari: ixodidae). | recently, a new rickettsia named 'candidatus rickettsia vini' belonging to the spotted fever group has been molecularly detected in ixodes arboricola ticks in spain, the czech republic, slovakia and turkey, with prevalence reaching up to 100 %. the aim of this study was to isolate this rickettsia in pure culture, and to describe it as a new rickettsia species. | 2016 | 27565956 |
| detection of vector-borne pathogens in cats and their ectoparasites in southern italy. | vector-borne pathogens are the subject of several investigations due to the zoonotic concern of some of them. however, limited data are available about the simultaneous presence of these pathogens in cats and their ectoparasites. the aim of the present study was to define the species of ectoparasites found on cats as well as to investigate vector-borne pathogens in cats and their ectoparasites in southern italy. | 2016 | 27160725 |
| canine vector-borne pathogens in semi-domesticated dogs residing in northern cambodia. | in southeast asia, the canine vector-borne pathogens babesia spp., ehrlichia canis, anaplasma platys, hepatozoon canis, haemotropic mycoplasmas and dirofilaria immitis cause significant morbidity and mortality in dogs. moreover, dogs have also been implicated as natural reservoirs for rickettsia felis, the agent of flea-borne spotted fever, increasingly implicated as a cause of undifferentiated fever in humans in southeast asia. the objective of this study was to determine the prevalence and div ... | 2016 | 27161452 |
| rickettsia felis, an emerging flea-borne rickettsiosis. | rickettsia felis is an emerging insect-borne rickettsial pathogen and the causative agent of flea-borne spotted fever. first described as a human pathogen from the usa in 1991, r. felis is now identified throughout the world and considered a common cause of fever in africa. the cosmopolitan distribution of this pathogen is credited to the equally widespread occurrence of cat fleas (ctenocephalides felis), the primary vector and reservoir of r. felis. although r. felis is a relatively new member ... | 2016 | 27340613 |
| limited evidence for rickettsia felis as a cause of zoonotic flea-borne rickettsiosis in southern california. | over 90% of human flea-borne rickettsioses cases in california are reported from suburban communities of los angeles and orange counties and are presumed to be associated with either rickettsia typhi or rickettsia felis infection. ctenocephalides felis (bouché) is considered the principal vector for both rickettsiae, and r. felis has largely replaced r. typhi as the presumptive etiologic agent based on the widespread incidence of r. felis in cat flea populations. however, with no evidence to con ... | 2016 | 27816916 |
| rickettsia felis: the next mosquito-borne outbreak? | 2016 | 27676348 | |
| fleas and ticks in carnivores from a domestic-wildlife interface: implications for public health and wildlife. | fleas and ticks are parasites of wild and domestic mammals, and can be vectors of several pathogens. in rural areas, domestic carnivores such as the domestic dog (canis lupus familiaris l.), may act as a "bridge" between natural areas and human settlements where ectoparasites can be used as a metric of such link. the aim of this study was to identify fleas, ticks, and rickettsia spp., collected from domestic and wild carnivores in a natural reserve and surrounding human settlements in central ch ... | 2016 | 27539151 |
| isolation and characterization of a novel rickettsia species (rickettsia asembonensis sp. nov.) obtained from cat fleas (ctenocephalides felis). | a novel rickettsial agent, 'candidatus rickettsia asembonensis' strain nmrciit, was isolated from cat fleas, ctenocephalides felis, from kenya. genotypic characterization of the new isolate based on sequence analysis of five rickettsial genes, rrs, glta, ompa, ompb and sca4, indicated that this isolate clustered with rickettsia felis urrwxcal2. the degree of nucleotide similarity demonstrated that isolate nmrciit belongs within the genus rickettsia and fulfils the criteria for classification as ... | 2016 | 27506201 |
| rickettsia felis: the complex journey of an emergent human pathogen. | rickettsia felis is an obligate intracellular bacterium that is different from other officially recognized rickettsial species. it has multiple genes of different origins, an incubation temperature of less than 32°c, and a conjugative plasmid. this rickettsia is commonly detected in febrile patients in sub-saharan africa. r. felis is frequently detected in cat fleas, but recently mosquitoes have been suspected to be able to transmit the bacterium. however, many aspects of the ecology and epidemi ... | 2016 | 27155905 |
| bacterial community in haemaphysalis ticks of domesticated animals from the orang asli communities in malaysia. | ticks are vectors in the transmission of many important infectious diseases in human and animals. ticks can be readily found in the semi-forested areas such as the settlements of the indigenous people in malaysia, the orang asli. there is still minimal information available on the bacterial agents associated with ticks found in malaysia. we performed a survey of the bacterial communities associated with ticks collected from domestic animals found in two orang asli villages in malaysia. we collec ... | 2016 | 27132518 |
| infection by rickettsia felis in opossums (didelphis sp.) from yucatan, mexico. | rickettsia felis is an emergent pathogen and the causative agent of a typhus-like rickettsiosis in the americas. its transmission cycle involves fleas as biological vectors (mainly ctenocephalides felis) and multiple domestic and synanthropic mammal hosts. nonetheless, the role of mammals in the cycle of r. felis is not well understood and many efforts are ongoing in different countries of america to clarify it. the present study describes for the first time in mexico the infection of two specie ... | 2016 | 27074326 |
| seroprevalence of antibodies to rickettsia typhi in the waikato region of new zealand. | the first reported new zealand-acquired case of murine typhus occurred near auckland in 1989. since then, 72 locally acquired cases have been recorded from northern new zealand. by 2008, on the basis of the timing and distribution of cases, it appeared that murine typhus was escalating and spreading southwards. to explore the presence of rickettsia typhi in the waikato region, we conducted a seroprevalence study, using indirect immunofluorescence, western blot, and cross-adsorption assays of blo ... | 2016 | 27040715 |
| exposure of dogs to spotted fever group rickettsiae in urban sites associated with human rickettsioses in costa rica. | the zoonotic transmission cycles of rickettsia rickettsii and other spotted fever group (sfg) rickettsiae in latin america have usually been associated with rural or sylvatic environments, although domestic dogs can be implicated in more populated settings. in this study, exposure of dogs to sfg rickettsiae in the greater metropolitan area of costa rica was investigated. dogs from sites associated with human cases and from dog shelters were evaluated by indirect immunofluorescence assay (ifa) us ... | 2016 | 26995323 |
| molecular detection of rickettsia felis in humans, cats, and cat fleas in bangladesh, 2013-2014. | high prevalence of rickettsia felis in patients with fever of unknown origin was revealed in the north-central bangladesh from 2012 to 2013. subsequently, in this study, prevalence of r. felis in cats and cat fleas (ctenocephalides felis), together with febrile patients, was studied by pcr detection of 17 kda antigen gene and dna sequencing. r. felis was detected in 28% (28/100) and 21% (14/68) of cat blood and cat flea samples, respectively, whereas 42% (21/50) of patients were positive for r. ... | 2016 | 26901499 |
| detection of rickettsia species in fleas collected from cats in regions endemic and nonendemic for flea-borne rickettsioses in california. | rickettsia typhi, transmitted by rat fleas, causes most human flea-borne rickettsioses worldwide. another rickettsia, rickettsia felis, found in cat fleas, ctenocephalides felis, has also been implicated as a potential human pathogen. in the continental united states, human cases of flea-borne rickettsioses are reported primarily from the southern regions of texas and california where the cat flea is considered the principal vector. in california, more than 90% of locally acquired human cases ar ... | 2016 | 26824189 |
| absence of serological evidence of rickettsia spp., bartonella spp., ehrlichia spp. and coxiella burnetii infections in american samoa. | little is known about the epidemiology of zoonotic diseases in american samoa (pacific). a review of literature did not identify any published information on human rickettsia spp., bartonella spp., ehrlichia spp. or coxiella burnetii infections in this country. to determine the presence of these diseases, we conducted a serosurvey of american samoans. the presence of immunoglobulin g antibodies against rickettsia felis, rickettsia typhi, rickettsia conorii, c. burnetii, bartonella henselae, bart ... | 2016 | 26965788 |
| molecular detection of bacteria in the families rickettsiaceae and anaplasmataceae in northern crested caracaras (caracara cheriway). | bacterial pathogens of the families anaplasmataceae and rickettsiaceae are often spread to humans or other animals from bites from infected arthropod hosts. recently, an increasing number of studies have implicated migratory birds in the circulation of these pathogens through the spread of arthropod vectors. however, few studies have examined the potential for resident bird populations to serve as reservoirs for these zoonoses. in this study, we used nested pcrs of the groesl and 17 kda genes to ... | 2016 | 26837860 |
| a molecular survey for francisella tularensis and rickettsia spp. in haemaphysalis leporispalustris (acari: ixodidae) in northern california. | francisella tularensis and rickettsia spp. have been cultured from haemaphysalis leporispalustris packard, but their prevalence in this tick has not been determined using modern molecular methods. we collected h. leporispalustris by flagging vegetation and leaf litter and from lagomorphs (lepus californicus gray and sylvilagus bachmani (waterhouse)) in northern california. francisella tularensis dna was not detected in any of 1,030 ticks tested by polymerase chain reaction (pcr), whereas 0.4% of ... | 2016 | 28031350 |
| rickettsioses in europe. | bacteria of the genera rickettsia and orientia (family rickettsiaceae, order rickettsiales) cause rickettsioses worldwide, and are transmitted by lice, fleas, ticks and mites. in europe, only rickettsia spp. cause rickettsioses. with improvement of hygiene, the risk of louse-borne rickettsiosis (epidemic typhus) is low in europe. nevertheless, recrudescent form of rickettsia prowazekii infection persists. there could be an epidemic typhus outbreak if a body lice epidemic occurs under unfavorable ... | 2016 | 26384814 |
| detection of rickettsiae in fleas and ticks from areas of costa rica with history of spotted fever group rickettsioses. | outbreaks of spotted fevers have been reported in costa rica since the 1950s, although vectors responsible for transmission to humans have not been directly identified. in this study, species of rickettsia were detected in ectoparasites from costa rica, mostly from five study sites where cases of spotted fevers have been reported. ticks and fleas were collected using drag cloths or directly from domestic and wild animals and pooled according to species, host, and location. pools were analyzed in ... | 2016 | 27592065 |
| rickettsia (rickettsiales: rickettsiaceae) vector biodiversity in high altitude atlantic forest fragments within a semiarid climate: a new endemic area of spotted-fever in brazil. | rickettsioses are re-emerging vector-borne zoonoses with a global distribution. recently, rickettsia sp. strain atlantic rainforest has been associated with new human spotted-fever (sf) cases in brazil, featuring particular clinical signs: eschar formation and lymphadenopathy. these cases have been associated with the tick species, amblyomma ovale from 2010 until 2015, the brazilian health department confirmed 11 human sf cases in the maciço de baturité region, ceará, brazil. the present study r ... | 2016 | 27480099 |
| dynamics of exposure to rickettsia parkeri in cattle in the paraná river delta, argentina. | several cases of human rickettsiosis caused by rickettsia parkeri were recently documented in the paraná river delta of argentina, where the tick vector is amblyomma triste koch. as cattle suffer recurrent a. triste infestations, they are at risk of becoming infected with r. parkeri herein we investigated the dynamics of r. parkeri and its a. triste vector in a herd of beef cattle. cattle were followed for 18 mo and samples were analyzed for the presence of antibodies against four rickettsia spe ... | 2016 | 26794232 |
| approach for classification and taxonomy within family rickettsiaceae based on the formal order analysis. | genome sequences of 36 rickettsia and orientia were analyzed using formal order analysis (foa). this approach takes into account arrangement of nucleotides in each sequence. a numerical characteristic, the average distance (remoteness) - "g" was used to compare of genomes. our results corroborated previous separation of three groups within the genus rickettsia, including typhus group, classic spotted fever group, and the ancestral group and orientia as a separate genus. rickettsia felis urrwxcal ... | 2016 | 26423020 |
| evidence of exposure to rickettsia felis in australian patients. | rickettsia felis is an emerging zoonosis, causing flea-borne spotted fever (fbsf). serological diagnosis is typically confounded by cross-reactivity with typhus group rickettsiae and prior to the development of specific serological methods, cases of fbsf in australia were misdiagnosed. patient sera tested between august 2010 and december 2013 and known to be seropositive to r. typhi by immunofluorescence antibody testing (ifat) were subsequently retested against r. felis using an r. felis-specif ... | 2016 | 28616481 |
| differential rickettsial transcription in bloodfeeding and non-bloodfeeding arthropod hosts. | crucial factors influencing the epidemiology of rickettsia felis rickettsiosis include pathogenesis and transmission. detection of r. felis dna in a number of arthropod species has been reported, with characterized isolates, r. felis strain lsu and strain lsu-lb, generated from the cat flea, ctenocephalides felis, and the non-hematophagous booklouse, liposcelis bostrychophila, respectively. while it is realized that strain influence on host biology varies, the rickettsial response to these disti ... | 2016 | 27662479 |
| [epidemiological and molecular profile of rickettsiosis in peruvian border locations]. | to determine the circulation of rickettsia in the years 2010 and 2011 in border locations in four regions ofperu and their clinical epidemiological and molecular characteristics. | 2017 | 28538849 |
| spotted fever: epidemiology and vector-rickettsia-host relationship in rio de janeiro state. | the eco-epidemiological scenario of spotted fever (sf), a tick-borne disease that affects humans and other animals in several countries around the world, was analyzed in rio de janeiro (rj) state, brazil. during the last 34 years, 990 sf cases were reported in rj (the brazilian state with the highest population density), including 116 cases confirmed by serology (rifi) or pcr, among 42.39% of the municipalities with reported cases of sf. the epidemiologic dynamics of sf in rj state are very hete ... | 2017 | 28424664 |
| high prevalence of rickettsia spp. in dog fleas (siphonaptera: pulicidae) in rural uganda. | fleas are known vectors of zoonotic agents. thirty-five fleas, including 28 ctenocephalides felis (bouché), four pulex irritans (l.), and three echidnophaga gallinacea (westwood) from 19 rural dogs from southwestern uganda were analyzed for the presence of rickettsia spp. (ompb, glta, and 17 kda fragment genes) and bartonella spp. (rpob and its genes) by pcr. rickettsial dna was detected in 27 out of 28 of ct. felis and in two out of four p. irritans. none of the e. gallinacea specimens harbored ... | 2017 | 28399271 |
| effect of rickettsia felis strain variation on infection, transmission, and fitness in the cat flea (siphonaptera: pulicidae). | rickettsia felis is a human pathogen transmitted by the cat flea, ctenocephalides felis (bouché) (str. lsu), as well as an obligate symbiont of the parthenogenic booklouse liposcelis bostrychophila (badonnel) (str. lsu-lb). the influence of genetic variability in these two strains of r. felis on host specialization and fitness and possible resulting differences on infection and transmission kinetics in c. felis is unknown. utilizing an artificial host system, cat fleas were exposed to a r. felis ... | 2017 | 28399259 |
| first detection of rickettsia typhi and rickettsia felis in fleas collected from client-owned companion animals in the southern great plains. | flea-borne rickettsiosis occurs worldwide and includes a number of pathogens, namely, rickettsia typhi and rickettsia felis. most studies in the united states have occurred in southern texas and california where flea-borne rickettsiosis is endemic, resulting in a lack of information from other regions of the country. between march and august 2016, 222 fleas were collected from 52 client-owned dogs and cats in two urban areas in oklahoma. fleas were identified using morphological characteristics ... | 2017 | 28399210 |
| rickettsial seropositivity in the indigenous community and animal farm workers, and vector surveillance in peninsular malaysia. | rickettsioses are emerging zoonotic diseases that are often neglected in many countries in southeast asia. rickettsial agents are transmitted to humans through exposure to infected arthropods. limited data are available on the exposure of indigenous community and animal farm workers to the aetiological agents and arthropod vectors of rickettsioses in peninsular malaysia. serological analysis of rickettsia conorii and rickettsia felis was performed for 102 individuals from the indigenous communit ... | 2017 | 28400593 |
| amblyomma sculptum: genetic diversity and rickettsias in the brazilian cerrado biome. | amblyomma sculptum (ixodida: ixodidae) berlese, 1888 is the most important tick vector in brazil, transmitting the bioagent of the most severe form of spotted fever (sf) in part of the cerrado (in the states of minas gerais and são paulo). in another part of the cerrado (central-west region of brazil), a milder form of sf has been recorded. however, neither the rickettsia nor the vector involved have been characterized. the aim of the current study was to analyse genetic variation and the presen ... | 2017 | 28752684 |
| comparative vertical transmission of rickettsia by dermacentor variabilis and amblyomma maculatum. | the geographical overlap of multiple rickettsia and tick species coincides with the molecular detection of a variety of rickettsial agents in what may be novel tick hosts. however, little is known concerning transmissibility of rickettsial species by various tick hosts. to examine the vertical transmission potential between select tick and rickettsial species, two sympatric species of ticks, dermacentor variabilis and amblyomma maculatum, were exposed to five different rickettsial species, inclu ... | 2017 | 28433729 |
| anaplasma, ehrlichia and rickettsia species infections in cats: european guidelines from the abcd on prevention and management | anaplasma species, ehrlichia species and rickettsia species are vector-borne pathogens infecting a wide variety of mammals, but causing disease in very few of them. infection in cats: anaplasma phagocytophilum is the most important feline pathogen among these rickettsial organisms, and coinfections are possible. little information is available on the pathogenesis of these agents in cats. clinical signs are usually reported soon after tick infestation. they are mostly non-specific, consisting of ... | 2017 | 28438088 |
| nationwide prevalence of rickettsia felis infections in patients with febrile illness in bangladesh. | from july 2015 to december 2016, the presence of rickettsial pathogens was investigated for 414 patients with unknown fever in eight places in all the divisions of bangladesh. rickettsia felis was identified in blood samples from all the regions (overall detection rate, 19.6%), suggesting nationwide prevalence of r. felis infections. | 2017 | 28831298 |
| rickettsia felis infection in febrile children, ghana. | rickettsial infections are an underrecognized cause of febrile illness in sub-saharan africa. to evaluate the epidemiology and clinical features of rickettsial disease in pediatric patients in ghana, we screened blood samples from febrile children aged less than 15 years presenting to an outpatient department in ghana's ashanti region for the presence of rickettsial dna. we detected rickettsia felis in 7/470 (1.5%) blood samples, using two independent real-time polymerase chain reactions. no oth ... | 2017 | 28115672 |
| serological evidence of exposure to rickettsia felis and rickettsia typhi in australian veterinarians. | rickettsia felis and rickettsia typhi are emerging arthropod-borne zoonoses causing fever and flu-like symptoms. seroprevalence and risk factors associated with exposure to these organisms was explored in australian veterinarians. | 2017 | 28285586 |
| molecular and serological evidence of flea-associated typhus group and spotted fever group rickettsial infections in madagascar. | rickettsiae are obligate intracellular bacteria responsible for many febrile syndromes around the world, including in sub-saharan africa. vectors of these pathogens include ticks, lice, mites and fleas. in order to assess exposure to flea-associated rickettsia species in madagascar, human and small mammal samples from an urban and a rural area, and their associated fleas were tested. | 2017 | 28259176 |
| limited evidence for rickettsia felis as a cause of zoonotic flea-borne rickettsiosis in southern california. | over 90% of human flea-borne rickettsioses cases in california are reported from suburban communities of los angeles and orange counties and are presumed to be associated with either rickettsia typhi or rickettsia felis infection. ctenocephalides felis (bouché) is considered the principal vector for both rickettsiae, and r. felis has largely replaced r. typhi as the presumptive etiologic agent based on the widespread incidence of r. felis in cat flea populations. however, with no evidence to con ... | 2017 | 28082625 |
| survey for rickettsiae within fleas of great gerbils, almaty oblast, kazakhstan. | little is known of the endemicity of flea-borne rickettsiae in kazakhstan. thus, a survey for rickettsiae within great gerbil fleas was conducted in almaty oblast. high prevalence of rickettsia asembonensis was detected among xenopsylla gerbilli, demonstrating that flea-borne rickettsiae are endemic to southeastern kazakhstan. interestingly, no rickettsia typhi were detected in these same fleas. | 2017 | 27992288 |
| "candidatus rickettsia asemboensis" in rhipicephalus sanguineus ticks, brazil. | "candidatus rickettsia asemboensis" is an obligate intracellular bacterium of the rickettsiales order, genetically related to species belonging to the rickettsia felis group, agents of flea-borne spotted fever. here we report for the first time the detection of "ca. r. asemboensis", a flea-associated organism, in rhipicephalus sanguineus ticks. it is the first occurrence of this emerging bacterium in brazil, which increases the geographical distribution of this r. felis-like agent. | 2017 | 27986544 |
| more bark than bite: comparative studies are needed to determine the importance of canine zoonoses in aboriginal communities. a critical review of published research. | the objective of this review was to identify and critique over forty years of peer-reviewed literature concerned with the transmission of canine zoonoses to aboriginal people and determine the zoonotic organisms documented in dogs in australian aboriginal communities. a systematic literature search of public health, medical and veterinary databases identified 19 articles suitable for critical appraisal. thirteen articles documented the occurrence of recognized zoonotic organisms in dogs in abori ... | 2017 | 28342271 |
| cat fleas (ctenocephalides felis) from cats and dogs in new zealand: molecular characterisation, presence of rickettsia felis and bartonella clarridgeiae and comparison with australia. | the cat flea (ctenocephalides felis) is the most common flea species parasitising both domestic cats and dogs globally. fleas are known vectors of zoonotic pathogens such as vector borne rickettsia and bartonella. this study compared cat fleas from domestic cats and dogs in new zealand's north and south islands to australian cat fleas, using the mitochondrial dna (mtdna) marker, cytochrome c oxidase subunit i and ii (cox1, cox2). we assessed the prevalence of rickettsia and bartonella using genu ... | 2017 | 28115179 |
| the fleas (siphonaptera) in iran: diversity, host range, and medical importance. | flea-borne diseases have a wide distribution in the world. studies on the identity, abundance, distribution and seasonality of the potential vectors of pathogenic agents (e.g. yersinia pestis, francisella tularensis, and rickettsia felis) are necessary tools for controlling and preventing such diseases outbreaks. the improvements of diagnostic tools are partly responsible for an easier detection of otherwise unnoticed agents in the ectoparasitic fauna and as such a good taxonomical knowledge of ... | 2017 | 28068343 |