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classes and crossreactivity of proteinases in the excretory-secretory products of caenorhabditis elegans.proteinases released during the in vitro maintenance of asynchronous cultures of the free-living nematode caenorhabditis elegans were characterized on the basis of subunit composition, fluorogenic substrate specificity, inhibitor sensitivity and ph optima. cysteine proteinases are present in the excretory-secretory products (esp) as indicated by the hydrolysis of cathepsin fluorogenic substrates and confirmed by immunoblotting. serine proteinases were predominant as indicated by substrate gel an ...200717381874
new method for simultaneous species-specific identification of equine strongyles (nematoda, strongylida) by reverse line blot hybridization.the ability of a reverse line blot (rlb) assay to identify 13 common species of equine small strongyles (cyathostomins) and to discriminate them from three strongylus spp. (large strongyles) was demonstrated. the assay relied on the specific hybridization of pcr-amplified intergenic spacer dna fragments of the nuclear ribosomal dna to membrane-bound species-specific probes. all cyathostomins examined were unequivocally identified and simultaneously discriminated from each other and from three la ...200717626168
a nonmineralized approach to abrasion-resistant biomaterials.the tooth-like mouthparts of some animals consist of biomacromolecular scaffolds with few mineral components, making them intriguing paradigms of biostructural materials. in this study, the abrasion resistance of the jaws of one such animal, the bloodworm glycera dibranchiata, has been evaluated by nanoindentation, nanoscratching, and wear testing. the hardest, stiffest, and most abrasion-resistant materials are found within a thin (<3 microm) surface layer near the jaw tip and a thicker (10-20 ...200717702868
detection and semi-quantification of strongylus vulgaris dna in equine faeces by real-time quantitative pcr.strongylus vulgaris is an important strongyle nematode with high pathogenic potential infecting horses world-wide. several decades of intensive anthelmintic use has virtually eliminated clinical disease caused by s. vulgaris, but has also caused high levels of anthelmintic resistance in equine small strongyle (cyathostomin) nematodes. recommendations aimed at limiting the development of anthelmintic resistance by reducing treatment intensity raises a simultaneous demand for reliable and accurate ...200817889881
effects of hydration on mechanical properties of a highly sclerotized tissue.the jaws of the bloodworm glycera dibranchiata consist principally of protein and melanin scaffolds with small amounts of unmineralized copper (cu) and mineralized atacamite (cu(2)cl(oh)(3)) fibers in distinct regions. remarkably, when tested in air, the regions containing unmineralized cu are the hardest, stiffest, and most abrasion resistant. to establish the functions of jaw constituents in physiologically relevant environments, this study examines the effects of hydration on their response t ...200818192350
the effects of strongylus vulgaris parasitism on eosinophil distribution and accumulation in equine large intestinal mucosa.eosinophilic granulocytes have been associated with parasite or immune-mediated diseases, but their functions in other disease processes remain unclear. cause and timing of eosinophil migration into the equine gastrointestinal mucosa are also unknown.200818482896
bilateral symmetry in crayfish behavioral reactions.the crayfish, procambarus cubensis, placed in the central area of a plus-maze preferred to go forward in about 50% of trials; they chose the right or left arm in 20.7 and 18.9% of the trials, respectively. in a t-maze, the difference between right and left directions was also insignificant. when exploring a plus-maze, the crayfish turned to 180 degrees at the end of the arms, then turned to 90 degrees going to the next arm. the mean difference between the right and left u-turns, and the right an ...200818652389
a cathepsin l-like protease from strongylus vulgaris: an orthologue of caenorhabditis elegans cpl-1.cathespin l-like proteases (cpls), characterized from a wide range of helminths, are significant in helminth biology. for example, in caenorhabditis elegans cpl is essential for embryogenesis. here, we report a cathepsin l-like gene from three species of strongyles that parasitize the horse, and describe the isolation of a cpl gene (sv-cpl-1) from strongylus vulgaris, the first such from equine strongyles. it encodes a protein of 354 amino acids with high similarity to other parasitic strongylid ...200919059238
anthelmintic efficacies of a tablet formula of ivermectin-praziquantel on horses experimentally infected with three strongylus species.in this blinded randomized and controlled study, the anthelmintic efficacy of a tablet formula of ivermectin-praziquantel was evaluated in horses experimentally infected with three species of strongylus larvae. eighteen previously dewormed horses were inoculated on study day 0 with third-stage larvae of strongylus vulgaris, strongylus equinus, and strongylus edentatus. the horses were randomly allocated to three groups (n = 6): test-drug (tablet formula), positive-control (reference gel), and ne ...200919488785
parasitism and colic.equids are hosts to dozens of species of internal parasites that infect no other domestic animals. virtually all horses, especially those exposed to pasture, experience some level of parasitism continuously. despite pathologic evidence of parasitic damage in various organs and tissues, few parasitisms are manifested systemically in well-managed horses. contrary to conventional wisdom, only three common parasitisms of horses are likely to be manifested as colic: strongylus vulgaris, parascaris eq ...200919580936
occurrence of strongyles (strongylidae) in horses from small farms on the basis of necropsy.three parts of the large intestine, i.e. the dorsal and ventral colon, and caecum in 41 working horses from small farms in southern poland were examined. five species of large strongyles (3 migratory species from genus strongylus and 2 non-migratory from genus triodontophorus) and as well as 17 species of cyathostomes were revealed. the prevalence of large strongyles was observed, accordingly: strongylus vulgaris--80.5%, s. equinus--9.8%, s. edentatus--4.9%, triodontophorus serratus--19.5% and t ...200919645353
ionoregulatory physiology of two species of african lungfishes protopterus dolloi and protopterus annectens.basic ionoregulatory physiology was characterized in two species of african lungfish, slender african lungfish protopterus dolloi and west african lungfish protopterus annectens, largely under aquatic conditions. there were no substantive differences between the two species. plasma [na], [cl] and [ca] were only 60-80% of those typical of freshwater teleosts, and plasma ca activity was particularly low. unidirectional na and cl influx rates from water were also very low, only c. 10% of teleost va ...200920738584
spatial niche competition among helminth parasites in horse's large intestine.the spatial distribution of large intestinal helminth parasites of 50 horses was studied. both adult and mucosal larval stages were examined and counted within the ventral colon, dorsal colon and caecum. thirty-three species of adult parasites were identified and their distribution in the three large intestinal regions reported, together with the localization of cyathostome encysted larvae and of empty mucosal cysts. in order to highlight interspecific interactions, both spearman pairwise correl ...201020153115
biodiversity and distribution of helminths and protozoa in naturally infected horses from the biosphere reserve la sierra madre de chiapas", méxico.a cross sectional survey was performed to identify gastrointestinal helminths and protozoans in naturally infected horses from the biosphere reserve known as "la sierra madre de chiapas", mexico (el triunfo and la sepultura). during a three-year survey, fecal samples from 90 horses and parasites from 2 necropsied animals were collected. five families from the nematoda class: ascaridae, kathlanidae, oxyuridae, strongylidae and trichostrongylidae were found, whereas, only one family from the class ...201020307938
prevalence of helminths in horses in the state of brandenburg, germany.the objective of the study was to estimate the prevalence of helminths in the horse population of the state of brandenburg, germany. one hundred and twenty-six horse farms in the state were selected by randomised stratified sampling. in total, 1,407 horses across all farms were examined coproscopically. the experimental unit was the horse farm: a farm was considered infected when at least one horse on the farm investigated was positive for helminth eggs. animal details such as age, breed and sex ...201121472400
prevalence of strongyles and efficacy of fenbendazole and ivermectin in working horses in el sauce, nicaragua.horses, mules and donkeys are indispensable farming and working animals in many developing countries, and their health status is important to the farmers. strongyle parasites are ubiquitous in grazing horses world-wide and are known to constitute a threat to equine health. this study determined the prevalence of strongyle infection, the efficacy of ivermectin and fenbendazole treatment, and strongyle re-infection rates of working horses during the dry months in nicaragua. one hundred and five ho ...201121570188
sustainable equine parasite control: perspectives and research needs.clinically important equine parasites are ubiquitous in managed horse populations. the traditional approach to parasite control is frequent administration of anthelmintics to all horses on a farm. however, increasing levels of anthelmintic resistance is forcing horse owners and veterinarians to shift this control paradigm. treatment regimens involving routine deworming of all horses throughout the year are now being replaced by more sustainable approaches, which take in to account the importance ...201122055611
strongylus vulgaris (looss, 1900) in horses in italy: is it still a problem?a post-mortem survey was carried out on 46 sardinian horses to evaluate the presence of strongylus vulgaris and associated pathology. horses were from local farms and had been treated with broad-spectrum anthelmintics at least 3 times a year. examination of the cranial mesenteric arterial system (cmas) showed parasite-induced lesions in all horses. s. vulgaris larvae were found in 39% of examined arteries, while their detection rate in coprocultures was 4%. histology, carried out on 26 horses, s ...201121962966
evaluation of conventional pcr for detection of strongylus vulgaris on horse farms.strongyle parasites are ubiquitous in grazing horses. of these, the bloodworm strongylus vulgaris is regarded as most pathogenic. increasing levels of anthelmintic resistance in strongyle parasites has led to recommendations of decreased treatment intensities, and there is now a pronounced need for reliable tools for detection of parasite burdens in general and s. vulgaris in particular. the only method currently available for diagnosing s. vulgaris in practice is the larval culture, which is la ...201121889849
fecundity of various species of strongylids (nematoda: strongylidae)--parasites of domestic horses.the aims of the study were to determine fecundity of several strongylid species parasitizing domestic horses and analyze possible relations between numbers of eggs in female uteri and size of both the eggs and the nematodes as well as the influence of fecundity on proportion of species in the strongylid community. twenty-five specimens from each of 15 strongylid species (strongylus vulgaris, strongylus edentatus, triodontophorus serratus, triodontophorus brevicauda, triodontophorus tenuicollis, ...201222903448
the strongylidae belonging to strongylus genus in horses from southeastern poland.postmortem parasitic examinations of the large intestines of 725 slaughtered horses from individual farmers in southeastern poland were carried out. the examinations were carried out monthly since february 2006 until january 2007 (except for august 2007 because of a technological stoppage in the slaughterhouse). the examinations included the intensiveness and extensiveness of the infestation of the strongylidae belonging to the strongylus genus. the strongylidae were found in 26.5% of the examin ...201222961235
real-time pcr evaluation of strongylus vulgaris in horses on farms in denmark and central kentucky.strongyle parasites are ubiquitous in grazing horses, and the large strongyle strongylus vulgaris is considered the most pathogenic helminth parasite of horses. recent investigations have suggested an association between occurrence of this parasite and usage of selective therapy based on regular fecal egg counts. the established diagnostic method for s. vulgaris involves larval culture and subsequent morphological identification of third stage larvae under the microscope. recently, a real-time p ...201222877828
[strongylids (nematoda: strongylidae) of domestic horses in ukraine: modern state of fauna and structure of the parasite community].species composition and structure of the strongylid community was studies on helminthological material collected from 162 domestic horses from 11 regions of ukraine by the in vivo method. animals were treated with anthelmintic drug "univerm" (0.2% aversectin c, russia). faecal samples (200 g each) were collected from every horse at 24, 36, 48 and 60 hours after treatment; all nematodes expelled (90.851 specimens) were collected and identified. thirty-three strongylid species from 12 genera (8 sp ...201222834350
strongylus vulgaris associated with usage of selective therapy on danish horse farms-is it reemerging?nematodes belonging to the order strongylida are ubiquitous in grazing horses, and the large strongyle strongylus vulgaris is considered the most pathogenic. this parasite was originally described widely prevalent in equine establishments, but decades of frequent anthelmintic treatment appears to have reduced the prevalence dramatically. increasing levels of anthelmintic resistance in cyathostomin parasites have led to implementation of selective therapy to reduce further development of resistan ...201222703964
predatory functional response and prey choice identify predation differences between native/invasive and parasitised/unparasitised crayfish.invasive predators may change the structure of invaded communities through predation and competition with native species. in europe, the invasive signal crayfish pacifastacus leniusculus is excluding the native white clawed crayfish austropotamobius pallipes.201222359673
association between large strongyle genera in larval cultures--using rare-event poisson regression.decades of intensive anthelmintic treatment has caused equine large strongyles to become quite rare, while the cyathostomins have developed resistance to several drug classes. the larval culture has been associated with low to moderate negative predictive values for detecting strongylus vulgaris infection. it is unknown whether detection of other large strongyle species can be statistically associated with presence of s. vulgaris. this remains a statistical challenge because of the rare occurren ...201323731556
hierarchical model for evaluating pyrantel efficacy against strongyle parasites in horses.anthelmintic resistance is an increasing challenge for the control of equine parasites. the fecal egg count reduction test (fecrt) is the practical gold standard method for evaluating reduction in anthelmintic efficacy, but the interpretation is complicated due to high levels of variability. a hierarchical statistical model was described for analysis of fecrt data from multiple farms to evaluate the role of biological factors in determining the strongyle efficacy of pyrantel pamoate in a study p ...201323680542
svsxp: a strongylus vulgaris antigen with potential for prepatent diagnosis.strongyle parasites are ubiquitous in grazing horses. strongylus vulgaris, the most pathogenic of the large strongyles, is known for its extensive migration in the mesenteric arterial system. the lifecycle of s. vulgaris is characterised by a long prepatent period where the migrating larvae are virtually undetectable as there currently is no test available for diagnosing prepatent s. vulgaris infection. presence of s. vulgaris larvae in the arterial system causes endarteritis and thrombosis with ...201323557195
recent advances in diagnosing pathogenic equine gastrointestinal helminths: the challenge of prepatent detection.parasites infecting horses are ubiquitous and clinically important across the world. the major parasitic threats to equine health are cyathostomins, parascaris equorum, anoplocephala perfoliata, and strongylus vulgaris. increasing levels of anthelmintic resistance reported world wide in equine parasites have led to recommendations of constructing sustainable parasite control programmes based on systematic surveillance of parasite levels. regulations at the european union level now make anthelmin ...201323199789
selective therapy in equine parasite control--application and limitations.since the 1960s equine parasite control has relied heavily on frequent anthelmintic treatments often applied with frequent intervals year-round. however, increasing levels of anthelmintic resistance in cyathostomins and parascaris equorum are now forcing the equine industry to change to a more surveillance-based treatment approach to facilitate a reduction in treatment intensity. the principle of selective therapy has been implemented with success in small ruminant parasite control, and has also ...201424702770
development of strongylus vulgaris-specific serum antibodies in naturally infected foals.strongylus vulgaris is regarded as the most pathogenic helminth parasite infecting horses. migrating larvae cause pronounced endarteritis and thrombosis in the cranial mesenteric artery and adjacent branches, and thromboembolism can lead to ischemia and infarction of large intestinal segments. a recently developed serum elisa allows detection of s. vulgaris-specific antibodies during the six-month-long prepatent period. a population of horses has been maintained at the university of kentucky wit ...201424433851
a polychaete's powerful punch: venom gland transcriptomics of glycera reveals a complex cocktail of toxin homologs.glycerids are marine annelids commonly known as bloodworms. bloodworms have an eversible proboscis adorned with jaws connected to venom glands. bloodworms prey on invertebrates, and it is known that the venom glands produce compounds that can induce toxic effects in animals. yet, none of these putative toxins has been characterized on a molecular basis. here we present the transcriptomic profiles of the venom glands of three species of bloodworm, glycera dibranchiata, glycera fallax and glycera ...201425193302
effects of daily pyrantel tartrate on strongylid population dynamics and performance parameters of young horses repeatedly infected with cyathostomins and strongylus vulgaris.strongylid infections are ubiquitous in grazing horse populations. infections with cyathostomin (small strongyle) and strongylin (large strongyle) nematodes have long been associated with clinical disease in horses, but little is known about their subclinical impact. a masked, randomized, controlled study was conducted to evaluate the effects of daily administration of pyrantel tartrate on body condition scores, weight gain, fecal egg counts, and total worm counts of young horses repeatedly inoc ...201424929448
physiologic and systemic acute phase inflammatory responses in young horses repeatedly infected with cyathostomins and strongylus vulgaris.migrating strongylus vulgaris and encysted cyathostomin larvae cause a localized inflammatory response in horses. it is unknown whether these larvae elicit a systemic acute phase response (apr), evidenced by changes in serum amyloid a (saa), haptoglobin (hp), iron (fe), albumin, or albumin/globulin (a/g) ratio. in this study, 28 horses were randomly allocated to receive either pyrantel tartrate or a pelleted placebo formulation in their daily feed. concurrent with treatment, all the horses were ...201424529577
cranial mesenteric arterial obstruction due to strongylus vulgaris larvae in a donkey (equus asinus).arteritis due to strongylus vulgaris is a well-known cause of colic in horses and donkeys. the current report describes a fatal incidence of arterial obstruction in cranial mesenteric artery caused by s. vulgaris infection in an adult donkey in which anthelmintic treatment was not regularly administered. necropsy findings of the abdominal cavity revealed a complete cranial mesenteric arterial obstruction due to larvae of s. vulgaris, causing severe colic. to the authors' knowledge, a complete cr ...201425678931
strongyle infections and parasitic control strategies in german horses - a risk assessment.as a consequence of the increasing levels of anthelmintic resistance in cyathostomes, new strategies for equine parasite control are being implemented. to assess the potential risks of these, the occurrence of strongyles was evaluated in a group of 1887 horses. the distribution of fecal egg counts (fecs), the frequency of anthelmintic drug use, and the deworming intervals were also analyzed. between june 2012 and may 2013, 1887 fecal samples from either selectively or strategically dewormed hors ...201425387542
serum strongylus vulgaris-specific antibody responses to anthelmintic treatment in naturally infected horses.strongylus vulgaris is the most pathogenic helminth parasite of horses, causing verminous endarteritis with thromboembolism and infarction. a serum enzyme-linked immunosorbent assay (elisa) has been validated for detection of antibodies to an antigen produced by migrating larvae of this parasite. the aim was to evaluate elisa responses to anthelmintic treatment in cohorts of naturally infected horses. fifteen healthy horses harboring patent s. vulgaris infections were turned out for communal gra ...201525358238
changes in serum strongylus vulgaris-specific antibody concentrations in response to anthelmintic treatment of experimentally infected foals.strongylus vulgaris is the most pathogenic nematode parasite of horses. its extensive migration in the mesenteric blood vessels can lead to life-threatening intestinal infarctions. recent work has shown that this parasite is still identified among managed horse populations. a serum enzyme-linked immunosorbent assay (elisa) has been developed for the detection of migrating larvae of s. vulgaris. previous work has documented an increase in elisa values following larvicidal treatment with ivermecti ...201526664946
evaluation of baermann apparatus sedimentation time on recovery of strongylus vulgaris and s. edentatus third stage larvae from equine coprocultures.traditional methods of diagnosing equine strongylinae infections require culturing feces, sedimenting the culture media in baermann apparatuses, collecting the sediment, and morphologically identifying recovered third stage larvae. however, this method is plagued by low negative predictive values. this study evaluated sedimentation time within the baermann apparatus by comparing larval recovery from the traditionally collected sediment, "sediment 1", and from the usually discarded remaining flui ...201525976635
prevalence of gastrointestinal helminth parasites of equids from organized farms of mumbai and pune.a total of 1,304 faecal samples of different species of equids were examined for presence of helminthic eggs from five different centres in mumbai and pune regions of maharashtra state from october 2011 to june 2012. overall prevalence of helminthic infestation was found to be 20.63 % with higher rate of occurrence in monsoon (31.29 %) followed by winter (20.40 %) and summer (14.23 %). four species of nematodes viz. strongyles (10.81 %), strongyloides westeri (13.19 %), parascaris equorum (0.23  ...201526063996
new multiplex pcr method for the simultaneous diagnosis of the three known species of equine tapeworm.although several techniques exist for the detection of equine tapeworms in serum and feces, the differential diagnosis of tapeworm infection is usually based on postmortem findings and the morphological identification of eggs in feces. in this study, a multiplex polymerase chain reaction (pcr)-based method for the simultaneuos detection of anoplocephala magna, anoplocephala perfoliata and anoplocephaloides mamillana has been developed and validated. the method simultaneously amplifies hypervaria ...201525498328
aneurysm of the cranial mesenteric artery as a site of carriage of salmonella enterica subsp. enterica serovar abortusequi in the horse.salmonella enterica subsp. enterica serovar abortusequi is a pathogen restricted to horses. our investigation targeted 4 draft horses (9-10 months old) kept on a japanese farm that had suffered an outbreak of s. abortusequi abortion. the 4 horses were suspected to be carriers of the bacterium owing to their high agglutination titers (≥1:2,560) in tube agglutination testing. the owners' on-farm observations confirmed that the horses had no apparent abnormalities, and s. abortusequi was not isolat ...201627271985
effect of vacuum packing and temperature on survival and hatching of strongyle eggs in faecal samples.strongyle eggs of helminths of livestock usually hatch within a few hours or days after deposition with faeces. this poses a problem when faecal sampling is performed in the field. as oxygen is needed for embryonic development, it is recommended to reduce air supply during transport and refrigerate. the present study therefore investigated the combined effect of vacuum packing and temperature on survival of strongyle eggs and their subsequent ability to hatch and develop into l3. fresh faecal sa ...201626827855
fecal parasite identification by microscopy and pcr in scimitar-horned oryx, oryx dammah, managed at two sites.the scimitar-horned oryx, oryx dammah, an endangered species extinct in the wild, is managed in various captive management programs and is the focus of reintroduction efforts. management variability can contribute to substantial parasite load differences, which can affect deworming programs and potentially transfer parasites to different regions with translocations. parasite studies in o. dammah are lacking. in this study, we determined fecal egg/oocyst counts of o. dammah in two captive herds, ...201627942456
purification of diverse hemoglobins by metal salt precipitation.although donated blood is the preferred material for transfusion, its limited availability and stringent storage requirements have motivated the development of blood substitutes. the giant extracellular hemoglobin (aka erythrocruorin) of the earthworm lumbricus terrestris (ltec) has shown promise as a blood substitute, but an efficient purification method for ltec must be developed to meet the potential large demand for blood substitutes. in this work, an optimized purification process that uses ...201626363116
density-dependent prey mortality is determined by the spatial scale of predator foraging.foraging theory predicts which prey patches predators should target. however, in most habitats, what constitutes a 'patch' and how prey density is calculated are subjective concepts and depend on the spatial scale at which the predator (or scientist) is observing. moreover, the predator's 'foraging scale' affects prey population dynamics: predators should produce directly density-dependent (ddd) prey mortality at the foraging scale, but inversely density-dependent (idd) mortality (safety-in-numb ...201626116266
assessment of risk factors associated with prevalence of strongyle infection in equines from central plain zone, punjab.a total of 311 equine faecal samples (190 horses and 121 mules) collected from six districts of central plain zone, punjab were examined using standard coprological methods. the results showed an overall prevalence of 27.33 % for strongyles with rare to mild type of infection as evident from egg per gram of faeces. in particular, amongst the examined samples, 17.90 % of horses and 42.14 % of mules were infected and the difference was statistically significant (p < 0.01). identification of the fa ...201627876953
time required by different anthelmintics to reach expected efficacy levels in horses infected by strongyles.the aim of this study was to determine the time required by different anthelmintic agents to reduce strongyle egg shedding in horses. fifty horses were divided into five homogenous groups based on faecal egg counts (fecs). treatment groups received either ivermectin; moxidectin; fenbendazole; piperazine; or no treatment (control group). faecal examinations were performed 4, 8, 12, 18, 24, 36 and 48h after the anthelmintic treatment. after this period, faecal samples were taken every 24h over the ...201627809986
strongylids in domestic horses: influence of horse age, breed and deworming programs on the strongyle parasite community.an extensive analysis of the relationships between strongylid egg shedding in domestic horses and the strongylid community structure in regard to the age of the horses, their breeds and different strategies of horse management, particularly with anthelmintic treatment programs was performed. domestic horses (n=197) of different ages (5 months to 22 years) and of various breeds from 15 farms with different types of deworming programs were included in this study. strongylids (totally, 82,767 speci ...201627523938
nonstrangulating intestinal infarction associated with strongylus vulgaris in referred danish equine cases.strongylus vulgaris is a pathogenic helminth parasite infecting horses and was once considered to be the primary cause of colic. migrating larvae cause ischaemia and infarction of intestinal segments. this knowledge is derived from case reports and experimental inoculations of parasite-naïve foals, and it remains unknown to what extent the parasite is associated with different types of colic.201625604521
comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system.we present the first molecular characterization of glycerotoxin (gltx), a potent neurotoxin found in the venom of the bloodworm glycera tridactyla (glyceridae, annelida). within the animal kingdom, gltx shows a unique mode of action as it can specifically up-regulate the activity of cav2.2 channels (n-type) in a reversible manner. the lack of sequence information has so far hampered a detailed understanding of its mode of action.201728259138
strongyle egg reappearance period after moxidectin treatment and its relationship with management factors in uk equine populations.parasitic nematodes, particularly cyathostomins, are ubiquitous in grazing horses world-wide. considerable burdens of cyathostomin larvae can encyst in the large intestinal wall. the most recommended treatment against these pathogenic stages is moxidectin. information is required on how effective moxidectin is against cyathostomin populations in different regions. the objectives here were to determine the efficacy of moxidectin treatment and estimate the strongyle egg reappearance period (erp) a ...201728249767
detection of strongylus vulgaris in equine faecal samples by real-time pcr and larval culture - method comparison and occurrence assessment.strongylus vulgaris has become a rare parasite in germany during the past 50 years due to the practice of frequent prophylactic anthelmintic therapy. to date, the emerging development of resistance in cyathostominae and parascaris spp. to numerous equine anthelmintics has changed deworming management and the frequency of anthelmintic usage. in this regard, reliable detection of parasitic infections, especially of the highly pathogenic s. vulgaris is essential. in the current study, two diagnosti ...201728077153
endoparasites of horses from the formiga city, located in center-west region of the state of minas gerais, brazil.with the aim of studying the endoparasite fauna of horses from the formiga city, located in center-west region of the state of minas gerais, 25 animals that were naturally infected with helminths were evaluated. by means of parasitological necropsies, different endoparasites were found. the subfamily cyathostominae presented the highest incidence, followed by trichostrongylus axei, oxyuris equi, triodontophorus serratus, strongyloides westeri, strongylus edentatus, habronema muscae, parascaris e ...201725517536
helminth egg excretion in horses kept under tropical conditions-prevalence, distribution and risk factors.increasing levels of anthelmintic resistance observed in equine cyathostomin parasites have led to recommendations of selective anthelmintic treatment strategies to lower the selection pressure favoring resistant populations. this principle is based on determining strongyle fecal egg counts from all herd members, and treating those exceeding a predetermined treatment cutoff. however, epidemiological information is lacking from horses kept under tropical conditions, where parasite burdens may be ...201728807303
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