Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [iminodimethylation, a method for pharmacomodulation in pyrimido-[3,4-a]-s-triazine series]. | primary amines react with two formaldehydes and compounds presenting two mobile hydrogen atoms, this reaction can be called iminodimethylation. this reaction can be used in order to perform a pharmacomodulation in the pyrimido [3,4-a]-s-triazine series. against epidermophyton floccosum, the activity is better when nitrogen 7 is not substituted, when the heroatom in position 2 is 0 instead of s and when an aromatic nucleus is directly linked to the nitrogen atom in position 3. | 1995 | 7741424 |
| antidermatophytic activity of garlic (allium sativum) in vitro. | interest in herbal medicine is enjoying a renaissance at present. garlic (allium sativum) is an intriguing herb with a long history of medicinal use for a variety of diseases including ringworm infections. | 1995 | 7790146 |
| in vitro susceptibility of fungi to acyclic inhibitors of 2,3-oxidosqualene cyclases. | in the present study we determine the antifungal properties of two acyclic inhibitors of 2,3-oxidosqualene cyclases: 22,23-epoxy-2-aza-2,3-dihydrosqualene (eas) and azasqualene alcohol (asa). fungistatic and fungicidal activity towards dermatophytes and other fungi involved in cutaneous and systemic infections was tested (48 isolates from 10 species). the tests were carried out by inoculating 10 microliters of mycelial homogenate in 1 ml of sabouraud glucose liquid medium containing serial dilut ... | 1996 | 8786759 |
| effect of glucose and thiamine concentrations on the formation of macroconidia in dermatophytes. occurrence of dysgonic microsporum canis strains in athens, greece. | data collected from multiple trials with 110 fresh and preserved clinical isolates of trichophyton mentagrophytes var. mentagrophytes, t. violaceum, t. rubrum, t. verrucosum, microsporum canis and epidermophyton floccosum revealed that production of macroconidia depends on glucose and thiamine concentrations in the medium. optimal macroconidia production was obtained at the critical concentrations of 5 g l-1 glucose and 0.6 g l-1 thiamine when the two compounds were used in combination. the same ... | 1996 | 8786761 |
| antifungal screening of seven new azole derivatives. | two strains of the dermatophyte epidermophyton floccosum were treated with seven new synthetic azole derivatives to determine their possible antifungal activity. among these, two diazopyrazoles (1-phenyl-3-methyl-4-diazo-5-methanesulphonamid and 1,3-dimethyl-4-diazo-5-methanesulphonamid) and the triazole (4-methyl-6-t-butylpyrazolo[3,4-d] [1,2,3]triazole) were inactive at the highest dose tested (100 micrograms/ml). the 4-methyl-6-phenyl-pyrazolo[3,4-d] [1,2,3]triazole produced only a partial in ... | 1996 | 8885417 |
| phylogeny of epidermophyton floccosum and other dermatophytes. | eleven strains of epidermophyton floccosum were compared with 5 microsporum and 5 trichophyton species with respect to the restriction fragment length polymorphism (rflp) of the mitochondrial dna to reveal their phylogenetic relationships. the phylogeny of 11 species showed that the three dermatophyte genera could not be separated from each other and could be considered to be congeneric. this result is not inconsistent with the results from ribosomal rna sequences. | 1996 | 8981778 |
| the spectrum of dermatophytes in northern malawi (africa). | between 1.5% and 2.5% of the population in karonga district, northern malawi (africa), were diagnosed as having tinea faciei, corporis, inguinalis or cruris in the course of a total population survey carried out between 1987 and 1989. with regard to the relative frequency distribution of dermatophytes, the main findings were the rarity of trichophyton rubrum (around 1%) and the predominance of microsporum audouinii (57%) in this part of africa. in the genital area epidermophyton floccosum was th ... | 1996 | 9009648 |
| dermatophytosis in schoolchildren in ekpoma, nigeria. | of 1400 pupils from two public primary schools in ekpoma, edo state, nigeria, who were screened for dermatophyte infection, 188 (13.4%) were infected. the causative agents isolated included microsporum audouinii in 88 (46.8%), trichophyton mentagrophytes in 48 (25.5%), t. rubrum in 40 (21.3%), t. tonsurans in four (2.1%) and epidermophyton floccosum in eight (4.3%). there were significant differences in the rate of infection between male and female schoolchildren as well as between children from ... | 1996 | 9009650 |
| human androgenic steroids affect growth of dermatophytes in vitro. | hormonal effects on fungal growth are of particular interest to medical mycology. in the skin, androgenic steroids metabolized within pilosebaceous units may have direct effects on dermatophytes that invade hair follicles. in this study, 10(-1) to 10(2) mg 1(-1) testosterone, 5-alpha-dihydrotestosterone, dehydroepiandrosterone, androstenedione and androstanedione were used in agar dilution assays to test their effects on thallus diameters of trichophyton rubrum, epidermophyton floccosum, t. tons ... | 1996 | 9009664 |
| dermatophytoses in the gdańsk area, poland: a 12-year survey. | a survey of dermatophytes and dermatophytoses was carried out among patients of the department of dermatology, medical university of gdańsk, in the years 1984-95. over the 12-year period, 1195 cases of ringworm were seen: 55% in men and 45% in women. listing the dermatophytes isolated and their frequencies as a percentage of the total are as follows: trichophyton mentagrophytes 42.1%, microsporum canis 26.0%, trichophyton rubrum 14.7%, epidermophyton floccosum 11.0%, trichophyton tonsurans 4.6%, ... | 1996 | 9009667 |
| [fungi and yeasts isolated in mycological studies in skin and nail infections in the netherlands, 1992-1993]. | to describe fungi and yeasts isolated from skin and nail infections in the netherlands. | 1996 | 8684495 |
| a study of dermatophytoses in hamadan, the governmentship of west iran. | in order to determine the extent and causative agents of dermatophytoses in the hamadan region of west iran; a study was made during a 9-month period from october 1991 to june 1992. a total of 7495 individuals were studied of whom 681 (9%) were suspect of having cutaneous mycoses. among them dermatophytoses were the commonest infections (259/681 = 38%). of 259 individuals infected with dermatophytes, tinea capitis were observed in 163 (62.9%); t. corporis in 27 (10.4%); t. manuum and t. cruris i ... | 1996 | 8751822 |
| fungi responsible for skin mycoses in turin (italy). | there has been a recent increase in the frequency of skin mycoses, coupled with changes in the epidemiology and distribution of the species responsible. periodic epidemiological analyses of these disease are thus required to ensure their efficacious control. hair fragments, skin scrapings, specimens from vesicles and blisters and nail parings were seeded on petri dishes loaded with sabouraud or mycosel agar, supplemented with chloramphenicol and with chloramphenicol plus cycloheximide respective ... | 1996 | 8767009 |
| clinicomicrobiological aspects of tinea cruris in madras. | a total of 242 patients with clinically diagnosed tinea cruris were screened and 181 (74.7 %) were found to be positive in culture for dermatophytes. 93.9% of infections were caused by trichophyton spp., of which 58.4% were trichophyton rubrum, 5.5% were epidermophyton floccosum, 3.8% were trichophyton tonsurans and we had a single isolate of microsporum gypseum complex. incidence of tinea cruris was higher in males (95.6%) than in females (4.4%). 45% of the cases were recurrent and 38% of cases ... | 1996 | 20948056 |
| oral terbinafine: a new antifungal agent. | to review the pharmacology, pharmacokinetics, efficacy, adverse effects, drug interactions, and dosage guidelines of terbinafine. available comparative data of terbinafine and other antimycotic agents are described for understanding the potential role of terbinafine in patient care. | 1997 | 9101008 |
| invasive disease due to epidermophyton floccosum in an immunocompromised patient with behçet's syndrome. | 1997 | 9243051 | |
| in vitro evaluation of antifungal properties of 8.o.4'-neolignans. | eighteen racemic 8.o.4'-neolignans with six different substitution patterns in rings a and b, in their ketone and in their erythro and threo alcoholic forms, were evaluated for antifungal activity by the agar dilution method. only the alcohols exhibited a broad spectrum of activities against microsporum canis, microsporum gypseum, tricophyton mentagrophytes, tricophyton rubrum, and epidermophyton floccosum. (+/-)-erythro-3,4-(methylenedioxy) -7-hydroxy-1'-allyl-3',5'-dimethoxy-8.o.4'-neolignan ( ... | 1997 | 9249968 |
| contact-sensing by hyphae of dermatophytic and saprophytic fungi. | contact-sensing or thigmotropism is the directional growth response of cells in relation to topographical guidance cues. thigmotropism is thought to play a major role in the location of infectable sites on plants by phytopathogenic fungi and has recently been shown to be a property of hyphae in the human pathogenic fungus candida albicans. here we show that hyphae of the dermatophytes epidermophyton floccosum, microsporum canis and trichophyton mentagrophytes reorientate their direction of growt ... | 1997 | 9292428 |
| molecular determination of dermatophyte fungi using the arbitrarily primed polymerase chain reaction. | dermatophytes are keratinophilic fungi capable of causing dermatophytosis (commonly known as tinea or ringworm) in humans and animals. previously, we reported the differentiation of the common dermatophytes trichophyton rubrum, t. mentagrophytes and t. tonsurans using a random primer 5'-acccgacctg-3' (opaa11) in the arbitrarily primed polymerase chain reaction (ap-pcr). in the present study, by examining additional dermatophytes including eight microsporum spp., 16 trichophyton species/subspecie ... | 1997 | 9349328 |
| some aspects of dermatophytoses seen at university hospital in florianópolis, santa catarina, brazil. | dematophytoses comprise mycoses which are very frequently diagnosed in the routine of clinical laboratories of florianópolis, like any other brazilian cities. however, no clinical or epidemiological studies data have been published for that city so far. to partially clarify these questions, we carried out a study on this subject on patients who sought the mycology services of hospital of federal university of santa catarina, from january 1995 to november 1996. the most prevalent dermatophyte was ... | 1997 | 9460252 |
| random amplification of polymorphic dna is useful for the differentiation of several anthropophilic dermatophytes. | the efficacy of random amplification of polymorphic dna (rapd) analysis, a polymerase chain reaction (pcr)-based technology, as a tool for differentiation of several anthropophilic dermatophytes, that is, trichophyton mentagrophytes var. interdigitale, t. rubrum and epidermophyton floccosum, was examined. total cellular dna extracted by a mini-preparation method were used as template dnas and pcrs were performed using five primers, all of which were synthesized 10-mers. all of the primers genera ... | 1997 | 9470403 |
| prevalence and aetiology of dermatophytoses in isfahan, iran. | in this study the prevalence and causative agents of dermatophytoses in isfahan, a large province of iran, were determined. of 16,578 clinically suspected cases 13.3% were affected with dermatophytoses. lesions of tinea capitis were the most prevalent clinical type of dermatophytoses (54.1%), followed by tinea corporis (23.8%) and tinea pedis (8.9%). trichophyton verrucosum was the most frequent causative agent (32.8%), followed by epidermophyton floccosum (17.6%), t. mentagrophytes (16.2%) and ... | 1997 | 9476518 |
| [dermatophytes isolated in our clinics. 5-year-study in zaragoza]. | this review summarizes the different species of dermatophytes isolates in our laboratory between 1991 and 1995. we describe the clinical forms and establish the distribution over this period of time. | 1997 | 9580210 |
| [synthesis and antifungal activities of 1-(2-[(substituted-phenyl) methyl]thio)-2-(2,4-difluorophenyl)ethyl-1h-1,2,4-triazoles]. | twenty-one 1-[2-[[(substituted-phenyl) methyl] thio]-2-(2, 4-difluorophenyl) ethyl]-1h-1,2,4-triazoles were synthesized and 19 compounds are reported for the first time. results of biological tests in vitro showed that the antifungal activities of all title compounds were better than or comparable to the activities of fluconazole. the antifungal activities of compounds 1-7 and 11-17 were better than or comparable to the activities of sulconazole. compounds 1, 2 and 5 were 512 times more active t ... | 1997 | 11596186 |
| a survey of dermatophytes isolated from human patients in the united states from 1993 to 1995. | a survey of dermatophytes, isolated from human patients seeking medical attention, was conducted for the years 1993 to 1995. data were collected from 23 states throughout the continental united states and the district of columbia and from 44 to 45 laboratories. these data were compared with the results of two earlier surveys (1979 to 1981 and 1985 to 1987). in contrast to the earlier surveys trichophyton tonsurans became the most frequently isolated dermatophyte (44.9%) followed by t. rubrum (41 ... | 1998 | 9704838 |
| antimicrobial activity of some 1,2-benzisothiazoles having a benzenesulfonamide moiety. | some sulfonamide and sulfonylurea derivatives of unsubstituted and 5-methylsubstituted 1,2-benzisothiazole were studied in vitro for their antimicrobial properties against bacteria and fungi. compounds 7 and 8 exhibited good antibacterial activity against gram positive bacteria. a strong synergism was observed when their growth-inhibitory effect was assayed in combination with trimethoprim by using bacillus subtilis and staphylococcus aureus as test microorganisms. the antimycotic action of benz ... | 1998 | 9713255 |
| [dermatophytosis in the greater resistencia area, chaco province, argentina]. | epidemiological characteristics of dermatophytoses in the metropolitan area of resistencia city are described. hair fragments, skin, scalp or nail scrapings were collected from 3.507 persons with dermatological symptoms of probable fungal origin. the mycological studies were performed by three mycological laboratories, one from a university institute and two from private laboratories. direct microscopic examinations showed fungi in 39.66% of samples, while the recovering of dermatophytes from cu ... | 1998 | 9744034 |
| 1998 william j. stickel bronze award. antifungal activity of melaleuca alternifolia (tea-tree) oil against various pathogenic organisms. | tea-tree oil (oil of melaleuca alternifolia) has recently received much attention as a natural remedy for bacterial and fungal infections of the skin and mucosa. as with most naturally occurring agents, claims of effectiveness have been only anecdotal; however, several published studies have recently demonstrated tea-tree oil's antibacterial activity. this study was conducted to determine the activity of tea-tree oil against 58 clinical isolates: candida albicans (n = 10), trichophyton rubrum (n ... | 1998 | 9791953 |
| butenafine. | butenafine is a new antifungal agent with primary fungicidal activity against dermatophytes such as trichophyton mentagrophytes, microsporum canis and trichophyton rubrum which cause tinea infections. 14c-labelled butenafine (approximately 30 micrograms/g tissue) was found within guinea-pig dorsal skin 24 hours after topical application. most of the drug was distributed into the epidermis including the horny layer. small amounts were found in the dermis, probably transported via sebaceous glands ... | 1998 | 9530545 |
| in vitro antifungal evaluation and studies on mode of action of eight selected species from the argentine flora. | twenty nine extracts belonging to eight species of the argentine flora reported as antifungal in folk medicine, were assayed for antifungal properties by using the agar dilution method, against a panel of yeasts, filamentous fungi as well as dermatophytes. nine extracts belonging to six species, exhibited a broad spectrum of activity against microsporum cants, microsporum gypseum, trichophyton mentagrophytes, trichophyton rubrum and epidermophyton floccosum, with mics ranging from 25 to 900 μg/m ... | 1998 | 23195989 |
| dermatophytosis and dermatomycosis in pune. | dermatophytosis and dermatomycosis in patients reporting to command hospital (sc) were studied over a period of 3 years. a total of 126 cases were investigated. commonest clinical diagnosis was tinea corporis (39.68%) followed by onychomycosis (20.63%). some patients had infections of multiple sites. direct examination under koh and dimethyl sulfoxide (dmso) revealed fungal elements in 43 (34.12%) cases. fungi were isolated from 44 (34.92%) cases. commonly isolated fungi were candida albicans 11 ... | 1999 | 28775555 |
| [dermatophytes isolated in hospital universitario 12 de octubre (madrid, spain).]. | over a 10 year period (january 1988 - december 1997), 3,241 dermatophyte strains were isolated from 18,465 specimens from patients in whom dermatophytosis was suspected clinically. this represents a 17.5% rate of isolation. trichophyton rubrum (38.44%), microsporum canis (28.75%), epidermophyton floccosum (14.5%) and trichophyton mentagrophytes (13.5%) were the dominant species, and trichophyton tonsurans (2.09%) has emerged, whilst in the previous decade it had virtually disappeared. our study ... | 1999 | 18473578 |
| a case of unna-thost disease accompanied by epidermophyton floccosum infection. | we report herein a case of 61-year-old man with unna-thost disease (nonepidermolytic hereditary palmoplantar keratoderma) who had been suffering from refractory dermatophyte infection. diffuse palmoplantar hyperkeratosis developed in his infancy. coarse scaling, fissures, marked erythema, and nail deformities appeared in his early adult life. microscopic examination revealed fungal elements in scales and nail particles. cultures of those scales isolated epidermophyton floccosum. genealogical stu ... | 1999 | 10063215 |
| phylogenetic classification and species identification of dermatophyte strains based on dna sequences of nuclear ribosomal internal transcribed spacer 1 regions. | the mutual phylogenetic relationships of dermatophytes of the genera trichophyton, microsporum, and epidermophyton were demonstrated by using internal transcribed spacer 1 (its1) region ribosomal dna sequences. trichophyton spp. and microsporum spp. form a cluster in the phylogenetic tree with epidermophyton floccosum as an outgroup, and within this cluster, all trichophyton spp. except trichophyton terrestre form a nested cluster (100% bootstrap support). members of dermatophytes in the cluster ... | 1999 | 10074502 |
| mono- and sesquiterpenes and antifungal constituents from artemisia species. | in addition to beta-sitosterol and alpha-amyrin detected in all the investigated species, the extract of the aerial parts of artemisia giraldii var. giraldii gave stigmasterol, daucosterol, sesamine, luteolin, eupafolin, hispidulin, eupatilin, belamcanidin, pinitol, artemin, ridentin, and a new antifungal monoterpene (named santolinylol) while that of the aerial parts of a. mongolica afforded sesamine, eupafolin, eupatilin, matricarin, and a new germacranolide (3-oxo-11 alpha h-germacra-1(10)e,4 ... | 1999 | 10083848 |
| identification of several clinical isolates of dermatophytes based on the nucleotide sequence of internal transcribed spacer 1 (its 1) in nuclear ribosomal dna. | nucleotide sequences of internal transcribed spacer 1 (its 1) in nuclear ribosomal dna from seven morphologically unidentified dermatophyte isolates were determined. the sequences were compared with those of typical isolates of trichophyton (t.) mentagrophytes var. interdigitale, t. rubrum, and epidermophyton floccosum. two of the isolates were classified as t. rubrum and the other five as t. mentagrophytes var. interdigitale. the results did not conflict with identifications using other molecul ... | 1999 | 10380427 |
| antifungal activities of seven west african combretaceae used in traditional medicine. | seven species of combretaceae were investigated for their antifungal activity against the pathogenic fungi candida albicans, epidermophyton floccosum, microsporum gypseum, trichophyton mentagrophytes and trichophyton rubrum. pteleopsis suberosa and terminalia avicennioides appear to be the most active plants. phytochemical screening shows that these plants are particularly rich in tannins and saponins, which might be responsible for their antifungal activity. | 1999 | 10473181 |
| onychomycosis in lahore, pakistan. | onychomycosis, a common nail disorder, is caused by yeasts, dermatophytes, and nondermatophyte molds. these fungi give rise to diverse clinical presentations. the present study aimed to isolate the causative pathogens and to determine the various clinical patterns of onychomycosis in the population in lahore, pakistan. | 1999 | 10487448 |
| in vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes. | thirty-four arylpropanoids and related compounds were evaluated in vitro for antifungal properties. among them, 22 phenyl-, 4 naphthyl-, and 4 phenanthrylpropanoids; naphthalene; phenanthrene; and 2-chloro-1-hexyl-1-propanone were tested against dermatophytes by the agar dilution method. alpha-halopropiophenones exhibited a broad spectrum of activities against microsporum canis, microsporum gypseum, trichophyton mentagrophytes, trichophyton rubrum, and epidermophyton floccosum, with mic values b ... | 1999 | 10543891 |
| epidemiology of dermatomycoses of humans in central poland. part iii. tinea pedis. | the total number of dermatophytoses (7393) included 2025 (27.4%) tinea pedis cases. etiological factors in descending order by contribution were: trichophyton rubrum (41.7%), trichophyton mentagrophytes var. granulosum (30.9%), t. mentagrophytes var. interdigitale (10.0%), epidermophyton floccosum (7.4%), t. mentagrophytes var. quinckeanum (6.9%), trichophyton tonsurans (2.3%), trichophyton spec. (0.4%), trichophyton terrestre (0.2%), trichophyton violaceum (0.1%). in the years 1987-93 the incid ... | 1999 | 10592702 |
| epidemiology of dermatomycoses of humans in central poland. part v. tinea corporis. | the total number of dermatophytoses (7393) included 2204 (29.8%) cases of tinea glabrosa. etiological factors in descending order were: microsporum canis (23.5%), trichophyton mentagrophytes var. granulosum (21.6%), trichophyton rubrum (17.8%), trichophyton tonsurans (10.4%), epidermophyton floccosum (7.7%), t. mentagrophytes var. quinckeanum (6.0%), microsporum gypseum (5.3%), trichophyton violaceum (3.7%), t. mentagrophytes var. interdigitale (2.3%), microsporum equinum (0.7%), trichophyton ve ... | 1999 | 10680444 |
| prevalence of dermatophytoses in the zarqa district of jordan. | a total of 350 clinically suspected cases of dermatomycoses were examined for causative fungi during july 1997 to september 1998. mycotic infection was demonstrable by microscopy and culture in 199 (56.8%) cases. the most common superficial mycotic infections were tinea pedis (35.2%) followed by tinea capitis (23.1%), tinea unguium (21.6%) and tinea corporis (10.6%). most of the infected patients were 1-9, 20-29 and 30-39 years old. men were mainly infected with tinea cruris and tinea pedis, whi ... | 1999 | 10685449 |
| phylogenetic relation of epidermophyton floccosum to the species of microsporum and trichophyton in chitin synthase 1 (chs1) gene sequences. | the nucleotide sequence of the chitin synthase 1 (chs1) gene of epidermophyton floccosum, an anthrophophilic dermatophyte which is the type species of the genus epidermophyton was analyzed to determine its phylogenetic relation to eight other dermatophyte species belonging to the genera microsporum and trichophyton, which were sequenced in our previous studies. a genomic dna fragment about 620 bp in length of the chs1 gene was amplified from e. floccosum by polymerase chain reaction (pcr) and wa ... | 1999 | 10823181 |
| the frequency of tinea pedis in patients with tinea cruris in tehran, iran. | the objective of this study is to define the frequency of tinea pedis in patients with tinea cruris. sixty patients (46 males and 14 females) entered our study. epidermophyton floccosum was the most frequently isolated fungus in tinea cruris. four patients (6.4%) had concurrent tinea pedis and the only isolate from the foot was trichophyton mentagrophytes. in three of them, the corresponding dermatophyte in the groin was e. floccosum. | 2000 | 10838845 |
| antifungal effects of hydrolysable tannins and related compounds on dermatophytes, mould fungi and yeasts. | a series of hydrolysable tannins and related compounds was evaluated for antifungal activities against filamentous fungi (epidermophyton floccosum; microsporum canis; microsporum gypseum; trichophyton mentagrophytes; trichophyton rubrum; trichophyton tonsurans; trichophyton terrestre; penicillium italicum; aspergillus fumigatus; mucor racemosus; rhizopus nigricans) and opportunistic yeasts (candida albicans; candida glabrata; candidata krusei; cryptococcus neoformans), using the agar dilution me ... | 2000 | 10928561 |
| [1996 epidemiological survey of dermatophytoses in japan. epidemiological investigation committee for human mycoses in the japanese society for medical mycology]. | an epidemiological investigation on dermatophytoses in japan for the year 1996 was carried out with the following results. the number of dermatomycoses patients visiting the fifteen cooperating institutes that year was 8,402. new outpatients with this condition accounted for 13.1% of all new outpatients in these institutes. dermatophytoses patients numbered 7,395 and were composed of: tinea pedis 4,764 (64.4%), tinea unguium 1,487 (20.1%), tinea corporis 558 (7.5%), tinea cruris 369 (5.0%), tine ... | 2000 | 10938521 |
| prevalence and risk factors of tinea unguium and tinea pedis in the general population in spain. | this study prospectively evaluated the prevalence and risk factors of tinea unguium and tinea pedis in the general adult population in madrid, spain. one thousand subjects were clinically examined, and samples of nails and scales from the interdigital spaces of the feet were taken from those patients presenting with signs or symptoms of onychomycosis and/or tinea pedis, respectively. in addition, a sample from the fourth interdigital space of both feet was collected from all individuals with a p ... | 2000 | 10970362 |
| known and novel terpenes from buddleja globosa displaying selective antifungal activity against dermatophytes. | lipophilic extracts of the stembark of buddleja globosa were found to have antifungal activity at 125 microg/ml against three dermatophytic fungal species but had no activity at 1000 microg/ml against four other fungal species or two yeast species. bioassay-guided fractionation of si gel column eluates using the sensitive fungal species resulted in active fractions from which were isolated five compounds that were characterized by spectroscopic methods as one novel and four known compounds. the ... | 2000 | 11000021 |
| [structural and biochemical characteristics of pathogenic fungus: cell walls, lipids and dimorphism, and action modes of antifungal agents]. | cell walls (0.1-0.5 microm in thickness) of dermatophytes, at least trichophyton mentagrophytes and epidermophyton floccosum, are built of microfibrils (20 nm in diameter) and matrix embedding the fibrils. these fibrils are composed of chitin (70-80%) and a small amount of glucans, and the matrix is composed of beta-1-3, beta1-6 glucan, glucomannan, galactomannan and peptides. another characteristic structure is the outermost layer (20-50 nm in thickness) of the cell wall, which consists of hydr ... | 2000 | 11064317 |
| antifungal activity of magnolol and honokiol. | two neolignan compounds, magnolol (5,5'-diallyl-2,2'-dihydroxybiphenyl, 1) and honokiol (5,5'-diallyl-2,4'-dihydroxybiphenyl, 2), were isolated from the stem bark of magnolia obovata and evaluated for antifungal activity against various human pathogenic fungi. compound 1 and 2 showed significant inhibitory activities against trichophyton mentagrophytes, microsporium gypseum, epidermophyton floccosum, aspergillus niger, cryptococcus neoformans, and candida albicans with minimum inhibitory concent ... | 2000 | 10728656 |
| an evaluation of the in vitro activity of terbinafine. | terbinafine has previously been shown to be highly active against dermatophytes and many other filamentous fungi. however, its activity against yeasts is controversial, with earlier reports suggesting that it has low activity, while more recent studies demonstrated that terbinafine is effective against yeasts. in this study, the in vitro activity of terbinafine was evaluated against a broad range of fungal isolates. we examined the susceptibility of 100 yeast strains (10 species including candid ... | 2000 | 10817232 |
| inhibitors of the fungal cell wall. synthesis of 4-aryl-4-n-arylamine-1-butenes and related compounds with inhibitory activities on beta(1-3) glucan and chitin synthases. | as part of our project devoted to the search for antifungal agents, which act via a selective mode of action, we synthesized a series of new 4-aryl- or 4-alkyl-n-arylamine-1-butenes and transformed some of them into 2-substituted 4-methyl-tetrahydroquinolines and quinolines by using a novel three-step synthesis. results obtained in agar dilution assays have shown that 4-aryl homoallylamines not possessing halogen in their structures, tetrahydroquinolines and quinolines, display a range of antifu ... | 2000 | 10819157 |
| broad spectrum herbal therapy against superficial fungal infections. | skin disease associated with keratinized tissues in animal and human beings has been investigated. the essential oil of eucalyptus pauciflora in vitro showed strong antifungal activity at 1.0 microl/ml against human pathogenic fungi, viz. epidermophyton floccosum, microsporum audouinii, m. canis, m. gypseum, m. nanum, trichophyton mentagrophytes, t. rubrum, t. tonsurans and t. violaceum. the oil has heavy doses of inoculum potential at 1.0 microl/ml. moreover, it did not exhibit any adverse effe ... | 2000 | 10657767 |
| prevalence and awareness of tinea pedis in italian sailors. | it is difficult to carry out studies on the prevalence of tinea pedis in the community. some studies are performed on selected groups of subjects, exposed to the same risk factors, i.e. schoolchildren, public bathers, athletes and military men. | 2000 | 11146348 |
| [1997 epidemiological survey of dermatophytoses in japan]. | an epidemiological investigation on dermatophytoses in japan for the year 1997 was carried out with the following results. the number of dermatomycoses patients visiting the fourteen cooperating institutes that year was 8,284. new outpatients with this condition accounted for 13.3% of all new outpatients in these institutes. dermatophytoses patients numbered 7,314 and were composed of: tinea pedis 4,901 (63.8%), tinea unguium 1,592 (20.7%), tinea corporis 557 (7.2%), tinea cruris 395 (5.1%), tin ... | 2001 | 11173330 |
| antidermatophytic properties of extracts from the leaves of aristolochia paucinervis pomel. | several fractions of a methanol extract from the leaves of aristolochia paucinervis pomel (aristolochiaceae) were screened for their antidermatophytic efficiency against different human pathogenic fungi responsible for tinea and other skin infections. the antifungal study was carried out by the macrodilution agar method and the results showed that, with the exception of the aqueous fraction, all the fractions exhibited antifungal activities against the dermatophytic fungi tested. the hexane frac ... | 2001 | 11180530 |
| tinea unguium in lahore, pakistan. | during a period of 1 year, out of 202 clinically suspected cases of tinea unguium, 53 (26%) were confirmed by mycological cultures for dermatophytes. trichophyton rubrum was the most common fungus isolated in 46 (87%) patients, followed by t. violaceum in four (7%), t. interdigitale in two (4%) and epidermophyton floccosum in one (2%). the disease was more common in adult males and fingernails were found to be affected more often than toenails. the distal and lateral variety was seen in 41 (77%) ... | 2001 | 11346265 |
| [etiopathogenesis, clinical picture and diagnosis of onychomycoses]. | etiology of onychomycoses: onychomycoses can be caused by dermatophytes, molds and yeasts. however, dermatophytes appear to be the chief organisms capable of a primary attack on the nail. by far the most frequent dermatophytes isolated from nails are trichophyton rubrum, t. mentagrophytes var. interdigitale and epidermophyton floccosum. molds virtually only invade toenails, but their role as a primary pathogen is still debated. yeasts have been isolated from diseased nails at highly different ra ... | 2001 | 11432322 |
| application of pcr to distinguish common species of dermatophytes. | this report describes the application of pcr fingerprinting for the identification of species and varieties of common dermatophytes and related fungi utilizing as a single primer the simple repetitive oligonucleotide (gaca)(4). the primer was able to amplify all the strains, producing species-specific profiles for microsporum canis, microsporum gypseum, trichophyton rubrum, trichophyton ajelloi, and epidermophyton floccosum. intraspecific variability was not observed for these species. instead, ... | 2001 | 11526185 |
| case report. disseminated tinea of the verrucous type due to epidermophyton floccosum. | a case is presented of an 8-year-old boy suffering from disseminated verrucous lesions with some purulent drainage on his right foot, shank, thigh, scrotum, penis, perianal area and abdomen. epidermophyton floccosum was isolated from these lesions. the patient was treated with oral ketoconazole for 4 months and the lesions resolved completely. there was no evidence of relapse during a 12-month follow-up. | 2001 | 11714070 |
| evaluation of lymphocytes subpopulations and natural killer cells in peripheral blood of patients treated for dermatophyte onychomycosis. | thirty-five patients with dermatophyte onychomycosis caused by trichophyton rubrum, t. mentagrophytes var. granulosum, t. tonsurans and epidermophyton floccosum were examined before treatment and 27 of these patients were examined again when they came to the control check up 3 months after completion of treatment. the immunological investigations, including evaluation of immunological competence, were performed in vivo through the determination of lymphoid cell immunophenotype by a flow cytometr ... | 2001 | 11820262 |
| dermatophytoses in prague, czech republic, between 1987 and 1998. | over a 12-year period, from 1987 to 1998, the spectrum of aetiological agents isolated from 11208 patients (6265 females and 4943 males) suspected of having dermatomycosis was analysed in the mycological laboratory of the department of dermatology, charles university, prague. the most frequently examined locations were toenails (34.9%), feet (15.6%), fingernails (12.8%), toe webs (11%), trunk (10%) and hands (8.7%). dermatophytes were isolated from 5605 (30.2%) of all 18528 samples examined. amo ... | 2001 | 11820263 |
| chitin synthase 1 (chs1) gene sequences of microsporum equinum and trichophyton equinum. | chitin synthase 1 (chs1) genes from microsporum equinum and trichophyton equinum were compared with those of the other dermatophytes. the chs1 nucleotide sequences of these dermatophytes from horses showed more than 80% similarity to those of arthroderma benhamiae, a. fulvum, a. grubyi, a. gypseum, a. incruvatum, a. otae, a. simii, a. vanbreuseghemii, epidermophyton floccosum, t. mentagrophytes var. interdigitale (t. interdigitale), t. rubrum and t. violaceum. especially high degree of nucleotid ... | 2001 | 11118744 |
| dermatophytes and other fungi associated with skin mycoses in tripoli, libya. | our objective in this study was to obtain information on the prevalence of fungi responsible for superficial mycoses in the region of tripoli, libya. | 2001 | 17264550 |
| antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin. | the phytoalexin resveratrol is commonly found in food and drinks, including red wine, grapes, and peanuts. many studies have shown that this compound has anti-inflammatory properties, and it has been ascribed as having health benefits that help to prevent cancer and coronary heart disease. a treatment that combines antimicrobial and anti-inflammatory actions may be desirable for alleviating many skin conditions that range in severity. therefore, we evaluated the antimicrobial activity of resvera ... | 2002 | 11841782 |
| [dermatophyte flora at the dermatology clinic of kimitsu chuo hospital from 1994 through 1999]. | kimitsu chuo hospital is located in the middle of chiba prefecture along tokyo bay. an epidemiological survey of dermatophytosis was made at the dermatology clinic of the hospital from january 1994 through december 1999. dermatophytosis patients numbered 2,580 and disease types were composed of: tinea pedis 1,656 (64.2%), tinea unguium 377 (14.6%), tinea corporis 308 (11.9%), tinea cruris 139 (5.4%), tinea manuum 92 (3.6%), tinea capitis 6 (0.2%) and tinea profunda 2 (0.1%). species frequencies ... | 2002 | 11865297 |
| tinea cruris in female prostitutes. | tinea cruris is a dermatophytosis that mainly affects males. infections in females are rare, and there are no known data on the frequency of tinea cruris in female prostitutes. we describe seven female prostitutes with tinea cruris with on age range of between 19-34 years (mean 25.3). each prostitute had a mean of 50 sexual partners per month. four trichophyton mentagrophytes (57.1%), 2 t rubrum (28.6%), and 1 epidermophyton floccosum (14.3%) isolates were cultered. tinea cruris transmission is ... | 2002 | 11913763 |
| a chemically modified tetracycline (cmt-3) is a new antifungal agent. | several chemically modified tetracycline analogs (cmts), which were chemically modified to eliminate their antibacterial efficacy, were unexpectedly found to have antifungal properties. of 10 cmts screened in vitro, all exhibited antifungal activities, although their efficacies varied. among these compounds, cmt-315, -3, and -308 were found to be the most potent as antifungal agents. the mics of cmt-3 against 47 strains of fungi in vitro were determined by using amphotericin b (amb) and doxycycl ... | 2002 | 11959581 |
| antifungal activity of 5 new synthetic compounds vs. trichophyton rubrum and epidermophyton floccosum. | the antifungal activity of five new synthetic compounds was evaluated on two dermatophytes: epidermophyton floccosum and trichophyton rubrum. the data showed that the imidazo-pyrazole and pyrazolo-thiazoles were not particularly effective, while the two pyrazole-thiocyanates proved highly active on both fungi. the most active 5-amino-3-methyl-1-phenylpyrazolo-4-thiocyanate was chosen to perform sem and tem morphological studies on both fungi. both sem and tem observations revealed interesting al ... | 2002 | 11998873 |
| dermatophytes and other fungi associated with skin mycoses in tripoli, libya. | this study sought to determine the prevalence of skin infections and their causative agents in the libyan population. samples were collected from 2224 patients attending the dermatology clinics of the tripoli medical centre (tmc) between august 1997 and december 1999 and were submitted to a mycology laboratory for analysis. diagnosis was confirmed by microscopic examination in 1180 cases (53.1%) and the causative agent was isolated and cultured in 1160 cases (52.2%). dermatophytes, malassezia fu ... | 2002 | 12000510 |
| mannan changes induced by 3-methyl-5-aminoisoxazole-4-thiocyanate, a new azole derivative, on epidermophyton floccosum. | the antifungal activity of 3-methyl-5-aminoisoxazole-4-thiocyanate, a new azole derivative, was studied on the dermatophyte epidermophyton floccosum. the compound strongly inhibited the in vitro growth of two different strains of the fungus and even induced profound morphogenetic anomalies. optical and electron microscopy showed that such treatment targets the endomembrane system, particularly the plasmalemma, causing abnormal extrusion of the wall mannans. this results in improper arrangement o ... | 2002 | 12051894 |
| [dehydroepiandrosterone metabolism by epidermophyton floccosum]. | steroid hormones may be relevant for the fungus-host relation in dermatophytoses. in contrast to most other hosts of dermatophytes, humans are characterized by a high cutaneous concentration of the adrenal androgen dehydroepiandrosterone (dhea) and its sulphate (dheas). to investigate whether the strictly anthropophilic dermatophyte epidermophyton floccosum can metabolize this steroid hormone, cultures of e. floccosum were supplemented with dhea. after 5 days of incubation the steroids in the cu ... | 2002 | 12073561 |
| use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes. | the sensititre yeastone antifungal panel was used to test 49 dermatophytes belonging to the species epidermophyton floccosum, microsporum gypseum, microsporum canis, trichophyton tonsurans, trichophyton rubrum, and trichophyton mentagrophytes. the mics of four antifungals obtained with the sensititre yeastone antifungal panel were compared with those obtained by the reference nccls microdilution method. the levels of agreement between the two methods (<or=2 dilutions) were 81.6% with amphoterici ... | 2002 | 12089289 |
| survey of dermatophyte infections in the lausanne area switzerland. | the dermatophytes are important in the swiss medical environment since 5-10% of consultations in dermatology concern mycotic infections. | 2002 | 12218248 |
| chemical analysis and antifungal activity of the essential oil of calea clematidea. | the chemical composition of the essential oils of calea clematidea baker obtained by hydrodistillation of the leaves and flowers was analysed by gc and gc/ms and the oils were assayed for their antifungal activities. the essential oil of the leaves showed a high content of a new natural epoxy terpenoid, named clemateol (ca. 70 %), with minor amounts of o-vanillin (6.5 %), spathulenol (4.2 %), alpha-terpinene (4.0 %), germacrene b (2.9 %), yomogi alcohol (1.8 %), ( e)-caryophylene (1.7 %), m-cyme ... | 2002 | 12357399 |
| urticaria associated with dermatophytosis. | although urticaria has been reported in association with tinea or other fungal infections, usually this relationship is considered coincidental. | 2002 | 12464169 |
| further evaluation of rwandan medicinal plant extracts for their antimicrobial and antiviral activities. | a total of 45 rwandan plant extracts, belonging to 37 different plant species out of 21 families, were investigated for their antibacterial, antifungal, and antiviral properties. the plants were selected on the base of their ethnomedicinal use against infections and autoimmune diseases. from all the plant extracts tested, only clematis hirsuta (leaves) showed a pronounced antifungal activity against candida albicans and the dermatophytes trichophyton rubrum, epidermophyton floccosum, and microsp ... | 2002 | 11801376 |
| dermatophytes isolated from patients in university hospital, kuala lumpur, malaysia. | a total of 576 dermatophytes were isolated from patients with a variety of skin infections from january 1993 to may 2000. ten species of dermatophytes were identified: epidermophyton floccosum (0.7%), microsporum audouinii (1.1%), m. canis (3.1%), m. gypseum (0.3%), trichophyton concentricum (3.5%), t. equinum (0.2%), t. mentagrophytes (36.1%), t. rubrum (53.8%), t. verrucosum (0.2) and t. violaceum (1.0%). the body sites most frequently affected by dermatophytes were the buttocks, nails and tru ... | 2002 | 12650596 |
| a study of dermatophytes and their in-vitro antifungal sensitivity. | of the 150 clinically suspected cases of dermatophytosis studied, majority of the cases were from age group 11-20 and 21-30 (51.4%), tinea corporis (48.7%) and tinea capitis (18%) were the commonest clinical types. the isolation rate was 24% (36) of which 19 (52.7%) were trichophyton rubrum, 11 (30.55%) were trichophyton mentagrophytes and 4 (11.1%) were trichophyton violaceum. one isolate each of microsporum gypseum & epidermophyton floccosum were obtained. griseofulvin proved to be the best dr ... | 2002 | 12696733 |
| [clinical and epidemiological survey of dermatophytoses in jaen (spain)] | prevalence of dermatophytosis, with respect to age and sex and dermatophyte species, in jaen was investigated during a period of three years (1996-1999). the prevalence of dermatophytosis over three years was 4.48 cases / 1000 inhabitants. the isolated species were: microsporum canis (48.6%), trichophyton mentagrophytes (27.1%), epidermophyton floccosum (10%), trichophyton rubrum (8.6%), trichophyton violaceum (4.3%), and microsporum gypseum (1.4%). the most frequently observed dermatophytoses w ... | 2002 | 12716229 |
| anti dermatophytic activity of azardirachta indica (neem) by invitro study. | the leaf and seed extracts of the plant azardirachta indica were tested for antidermatophytic activity against dermatophytes such as trichophyton ruberum, trichophyton, mentagrophytes, trichophyton violaceum, microsporum nanum and epidermophyton floccosum by tube dilution technique. the minimum inhibitory concentration (mic) of neem seed extract was found to be lower tan that of neem leaf when tested against different species of dermatophytes. | 2002 | 12785173 |
| rapid identification of trichophyton tonsurans by pcr-rflp analysis of ribosomal dna regions. | culture morphology of trichophyton (t.) tonsurans, an emerging pathogen of dermatophytosis in japan, varies widely and species level identification is sometimes very difficult. reliable molecular markers are expected to be introduced for their identification. | 2003 | 12788526 |
| dermatomycoses in the rijeka area, croatia, before, during and after the war 1990-1999. | the frequency of dermatomycoses as well as the spectrum of causative agents in the rijeka area, northwestern part of croatia, in the periods before and during the war (1990-1994) and in the postwar period (1995-1999) were analyzed. a total of 20 463 patients with clinically suspected dermatomycoses referred to the department of dermatovenerology, clinical hospital center rijeka, was examined. in the period from 1990 till 1994, 2462 samples were positive, compared with 2250 positive samples durin ... | 2003 | 12801365 |
| antifungal activity of the methanolic extract and alkaloids of glaucium oxylobum. | the methanolic extract and total alkaloids of the aerial parts of glaucium oxylobum exhibited good activity against microsporum gypseum, microsporum canis, trichophyton mentagrophytes and epidermophyton floccosum. four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compounds responsible for the antifungal activity of this plant. | 2003 | 12837370 |
| inhibition of dermatophytes by optical brighteners. | the aim of this study was to investigate a possible effect of optical brighteners on the growth of dermatophytes. typical strains of trichophyton rubrum, t. mentagrophytes, microsporum canis and epidermophyton floccosum were grown on agar plates containing two different brighteners of stilbenedisulfonic acid type in concentrations between 5 x 10(-5) and 1 x 10(-2) mol l-1 and their thallus diameters were compared with controls. in addition, hyphae grown with brighteners were compared with contro ... | 2003 | 12870200 |
| [analysis of dermatophyte flora at a private clinic in sapporo during the period 1992 to 2001]. | statistical analysis was made of a total of 5530 patients (6798 cases) of dermatophytoses presenting at our private clinic during the period 1992 to 2001. the number of patients and cases represents 8.0% and 9.8% of the entire outpatient population during that time, respectively. sex ratio (male/female) was 1.5. among the 6798 dermatophytoses cases, tinea pedis was most frequent (65.8%), followed by tinea unguium (20.7%), tinea cruris (7.2%), tinea corporis (3.9%), tinea manuum (2.4%) and tinea ... | 2003 | 12913811 |
| study of solar photosensitization processes on dermatophytic fungi. | the antifungal activity of solar simulator was evaluated in presence of haematoporphyrin derivative (hpd), methylene blue (mb) and toluidine blue o (tbo) as photosensitizers. seven dermatophytes were used as test fungi. the solar simulator at fluence rate 400 w/m2 for 30 minutes induced marked inhibition for spore germination of the photosensitized fungi. the rate of inhibition varied according to the fungal species and concentration of the photosensitizer. there was an increase in percentage in ... | 2003 | 12916729 |
| [the change of dermatophyte spectrum in dermatomycoses]. | the spectrum of dermatophytes out of mycotic skin lesions had changed in last 70 years. before the second world war in germany microsporum audouinii and epidermophyton floccosum held the first position, since the fifties of last century trichophyton rubrum is the most frequently isolated dermatophyte accounting for 80-90% of the strains, followed by t. mentagrophytes. this development is typical for central and north europe and is connected with the increase in the incidence of tinea pedis. in c ... | 2003 | 12955853 |
| bioactive alkyl phenols and embelin from oxalis erythrorhiza. | the benzoquinone embelin and four alkyl phenols were isolated from an argentinean collection of oxalis erythrorhiza. 3-heptadecyl-5-methoxy-phenol is reported for the first time. the structures were determined by spectroscopic methods. embelin presented inhibitory effect on methicillin-resistant staphylococcus aureus, escherichia coli and the dermatophytic fungi epidermophyton floccosum, microsporum canis, microsporum gypseum, trichophyton mentagrophytes and trichophyton rubrum with mics ranging ... | 2003 | 12963150 |
| antifungal activity of fractions and two pure compounds of flowers from wedelia paludosa (acmela brasiliensis) (asteraceae). | wedelia paludosa (acmela brasiliensis) (asteraceae), a traditionally used native brazilian medicinal plant, showed antifungal activity against dermatophytes in dilution tests. the hexane, dichloromethane and butanol fractions displayed activity against epidermophyton floccosum, trichophyton rubrum and trichophyton mentagrophytes, with minimal inhibitory concentrations between 250 and 1000 microg/ml. two pure compounds, identified as kaurenoic acid (1) and luteolin (2), also showed activity again ... | 2003 | 12967035 |
| antifungal properties of novel n- and alpha,beta-substituted succinimides against dermatophytes. | the synthesis and antifungal properties of a series of new n-aryl alpha,beta-substituted succinimides against a panel of dermatophytes of clinical relevance are reported. among those compounds possessing a n-phenyl substituent, 7-thia-2-azabicyclo[2,2,1]hept-2-en-3-amine[5,6-c]succinimide was the better inhibitor of trichophyton rubrum, the major ethiological agent of all infections produced by dermatophytes. in contrast, succinimides containing a n-(p-sulfonylphenyl) substituent, only inhibited ... | 2003 | 12785125 |
| characteristics of superficial mycoses in malta. | a study was conducted to determine the chief agents of superficial mycoses in malta. data were collected over a 5-year period from mycologic investigations carried out on all dermatologic specimens sent to the mycology laboratory at st. luke's hospital in malta. | 2003 | 12694490 |
| essential oil analysis and antimicrobial activity of eight stachys species from greece. | the volatile composition of eight stachys species has been studied. the investigated taxa were st. alopecuros (l.) bentham., st. scardica (griseb.) hayek, st. cretica l. ssp. cretica, st. germanica l. ssp. heldreichii (boiss.) hayek, st. recta l., st. spinulosa l., st. euboica rech. and st. menthifolia vis., growing wild in greece. the essential oils were obtained by hydrodistillation in a modified clevenger-type apparatus, and their analyses were performed by gc and gc-ms. identification of the ... | 2003 | 13679097 |
| tinea pedis observed in cagliari, italy, between 1996 and 2000. | the aim of this study was to verify the incidence of tinea pedis in patients observed in the department of dermatology of the university of cagliari, italy, in the period from 1996 to 2000. we examined 722 patients, 536 with lesions and 186 without lesions of the feet and in 169 of them (23.4%) we diagnosed tinea pedis. all patients suffering from tinea pedis belonged to the group with lesions. in the 536 patients with clinical manifestations which were evident to a certain degree, microscope an ... | 2003 | 12588481 |
| clinical and mycological status of the trichophyton mentagrophytes (interdigitale) syndrome of chronic dermatophytosis of the skin and nails. | the syndrome of tinea pedis caused by human-adapted trichophyton mentagrophytes (interdigitale) can be recognized by two signs not characteristically seen in tinea pedis caused by t. rubrum and epidermophyton floccosum:1 bullous > 2 mm vesicles in the thin skin of the plantar arch and along the sides of the feet and heel adjacent to the thick plantar stratum corneum,2 and white superficial onychomycosis. the relationship of the syndrome to zoophilic t. mentagrophytes remains in question. | 2003 | 14521690 |
| constituents of the argentinian medicinal plant baccharis grisebachii and their antimicrobial activity. | the resinous exudate of baccharis grisebachii which is used to treat ulcers, burns, and skin sores in argentina showed activity towards dermatophytes and bacteria. two diterpenes, eight p-coumaric acid derivatives, and two flavones were isolated from the exudate and the structures elucidated by spectroscopic methods. 3-prenyl-p-coumaric acid and 3,5-diprenyl-p-coumaric acid were active towards epidermophyton floccosum and trichophyton rubrum with mics of 50 and 100-125 microg/ml, respectively. t ... | 2003 | 14522435 |
| ciclopirox gel in the treatment of patients with interdigital tinea pedis. | background tinea pedis (athlete's foot) is the most common fungal infection in the general population. ciclopirox, a broad-spectrum hydroxypyridone antifungal, has proven efficacy against the organisms commonly implicated in tinea pedis; trichophyton rubrum, t.mentagrophytes and epidermophyton floccosum. | 2003 | 14567368 |
| [erythema nodosum induced by kerion celsi in a child with hypomelanosis of ito]. | a 3-year-old boy presented with an 8 week history of inflammatory nodular lesions on the scalp. shortly afterwards painful subcutaneous nodules developed on the lower legs. epidermophyton floccosum was isolated from the scalp lesions and a diagnosis of erythema nodosum induced by kerion celsi of the scalp was made. the patient was started on oral therapy with 250 mg/day griseolfuvin, associated with topical eosine and myconazol. erythema nodosum represents a reaction pattern to a wide variety of ... | 2003 | 14676734 |
| occurrence of dermatomycoses and in-vitro therapeutic efficacy of three antifungal drugs on the growth of epidermophyton floccosum. | the occurrence of dermatomycoses and the in-vitro therapeutic efficacy of some antifungal agents on dermatomycotic organisms were investigated. of the 550 primary school children screened, the incidence was one hundred (18%), 70 were males (representing 20% of the males screened) and 30 females (15% of the females sampled). the differences between male and female prevalence were insignificant. three species of dermatophytes were isolated and identified. these were microsporum canis, trichophyton ... | 2003 | 14682454 |
| itraconazole pulse therapy in the treatment of disto-lateral subungual onychomycosis. | to assess the efficacy of itraconazole pulse therapy in disto-lateral subungual onychomycosis. | 2003 | 14700485 |