Publications

phytochemical compounds and antioxidant activity in different cultivars of cranberry (vaccinium macrocarpon l).	cranberries can be a component of a healthy diet, because they are a great source of health-promoting compounds and nutrients. the aims of this study were to evaluated phytochemicals and antioxidant activity in 6 cultivars of cranberry fruit grown in poland. the content of polyphenols, carotenoids, chlorophylls, and triterpenoids were determined with the use of uplc-pda-ms/ms, although antioxidant activity was examined with dpph, abts, and frap assays. the cvs. "franklin," "howes," and "stevens" ...	2017	28973819
cranberry proanthocyanidins - protein complexes for macrophage activation.	in this work we characterize the interaction of cranberry (vaccinium macrocarpon) proanthocyanidins (pac) with bovine serum albumin (bsa) and hen egg-white lysozyme (hel) and determine the effects of these complexes on macrophage activation and antigen presentation. we isolated pac from cranberry and complexed the isolated pac with bsa and hel. the properties of the pac-protein complexes were studied by matrix assisted laser desorption ionization time of flight mass spectrometry (maldi-tof ms), ...	2017	28861555
gypsy moth herbivory induced volatiles and reduced parasite attachment to cranberry hosts.	interactions between species can have cascading effects that shape subsequent interactions. for example, herbivory can induce plant defenses that affect subsequent interactions with herbivores, pathogens, mycorrhizae, and pollinators. parasitic plants are present in most ecosystems, and play important roles in structuring communities. however, the effects of host herbivory on parasitic plants, and the potential mechanisms underlying such effects, are not well known. we conducted a greenhouse stu ...	2017	28803341
characterization and quantification of flavonoids and organic acids over fruit development in american cranberry (vaccinium macrocarpon) cultivars using hplc and apci-ms/ms.	cranberry flavonoids, including anthocyanins, flavonol glycosides and proanthocyanidins, and organic acids were characterized and quantified by hplc and lc-ms/ms during fruit development and ripening in eight cranberry cultivars. anthocyanin biosynthesis initiated at early fruit development and reached highest level in mature fruit, with significant differences between cultivars. major flavonol glycosides, including the most abundant quercetin-3-galactoside and myricetin-3-galactoside, showed co ...	2017	28716425
effect of sweetened dried cranberry consumption on urinary proteome and fecal microbiome in healthy human subjects.	the relationship among diet, human health, and disease is an area of growing interest in biomarker research. previous studies suggest that the consumption of cranberries (vaccinium macrocarpon) could beneficially influence urinary and digestive health. the present study sought to determine if daily consumption of sweetened dried cranberries (sdc) changes the urinary proteome and fecal microbiome, as determined in a prospective sample of 10 healthy individuals. baseline urine and fecal samples we ...	2017	28618237
[evaluation of the effects of a natural dietary supplement with cranberry, noxamicina® and d-mannose in recurrent urinary infections in perimenopausal women].	the female genital apparatus, the urinary tract and the perineal supporting tissues share a common embryological origin, whose differentiation depends on the action of estrogens. in adult women, the progressive decline of the ovarian function, with the ensuing estrogen deprivation, reduces tissue tropism causing urogenital atrophy, which makes these organs much more susceptible to traumatisms and urinary infections. the disorders associated with changes in the urogenital tract of peri- and postm ...	2017	28608666
morphometric abnormalities in spleen and kidney of the progeny of mice fed american cranberry extract (vaccinium macrocarpon) during pregnancy and lactation.	cranberries and cranberry-derived diet supplements are often recommended for the treatment of urinary tract infections, also during pregnancy. these products contain strongly anti-angiogenic chemical compounds which could not be indifferent to the developing fetus. in the present work we evaluated the effect of feeding pregnant and lactating mice american cranberry extract (daily dose 0.88 mg) on the morphology and some parameters of spleen and kidney function of their adult progeny. six weeks a ...	2017	28525344
cranberry (vaccinium macrocarpon) extract treatment improves triglyceridemia, liver cholesterol, liver steatosis, oxidative damage and corticosteronemia in rats rendered obese by high fat diet.	obese individuals have higher production of reactive oxygen species, which leads to oxidative damage. we hypothesize that cranberry extract (ce) can improve this dysfunction in hfd-induced obesity in rats since it has an important antioxidant activity. here, we evaluated the effects of ce in food intake, adiposity, biochemical and hormonal parameters, lipogenic and adipogenic factors, hepatic morphology and oxidative balance in a hfd model.	2017	28501921
construction of a high-density american cranberry (vaccinium macrocarpon ait.) composite map using genotyping-by-sequencing for multi-pedigree linkage mapping.	the american cranberry (vaccinium macrocarpon ait.) is a recently domesticated, economically important, fruit crop with limited molecular resources. new genetic resources could accelerate genetic gain in cranberry through characterization of its genomic structure and by enabling molecular-assisted breeding strategies. to increase the availability of cranberry genomic resources, genotyping-by-sequencing (gbs) was used to discover and genotype thousands of single nucleotide polymorphisms (snps) wi ...	2017	28250016
flight synchrony among the major moth pests of cranberries in the upper midwest, usa.	the cranberry fruitworm (acrobasis vaccinii riley), sparganothis fruitworm (sparganothis sulfureana clemens), and blackheaded fireworm (rhopobota naevana hübner) are historically significant pests of cranberries (vaccinium macrocarpon aiton) in the upper midwest (wisconsin), usa. their respective natural histories are well documented but correlations between developmental benchmarks (e.g., larval eclosion) and degree-day accruals are not yet known. treatment timings are critical to the optimizat ...	2017	28245642
inhibitory effect of cranberry extract on periodontopathogenic biofilm: an integrative review.	combating biofilm-dependent oral infections involves the use of synthetic antibiotics, which are often associated with bacterial resistance and adverse effects. as a result, herbs such as cranberry have emerged as an alternative treatment. the aim of this study was to evaluate, through an integrative literature review, the effectiveness of cranberry extract on cultures and biofilms of periodontopathogenic bacteria.	2017	29242685
antiadhesive activity and metabolomics analysis of rat urine after cranberry (vaccinium macrocarpon aiton) administration.	cranberry (vaccinium macrocarpon aiton) is used to treat noncomplicated urinary tract infections (utis). a-type procyanidins (pac-a) are considered the active constituents able to inhibit bacterial adhesion to the urinary epithelium. however, the role of pac-a in utis is debated, because of their poor bioavailability, extensive metabolism, limited knowledge about urinary excretion, and contradictory clinical trials. the effects of 35-day cranberry supplementation (11 mg/kg pac-a, 4 mg/kg pac-b) ...	2017	28635280
enteric-coated and highly standardized cranberry extract reduces antibiotic and nonsteroidal anti-inflammatory drug use for urinary tract infections during radiotherapy for prostate carcinoma.	worldwide, bacterial resistance to antibiotic therapy is a major concern for the medical community. antibiotic resistance mainly affects gram-negative bacteria that are an important cause of lower urinary tract infections (lutis). pelvic irradiation for prostate cancer is a risk factor for lutis. cranberry extract is reported to reduce the incidence of lutis. the prophylactic role of an enteric-coated, highly standardized cranberry extract (vo370(®)) in reducing luti episodes, urinary discomfort ...	2017	28491861
inhibitory activity of chokeberry, bilberry, raspberry and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3t3-l1 adipose cells.	berries are a rich source of antioxidants and phytochemicals that have received considerable interest for their possible relations to human health. in this study, the anti-adipogenic effect of polyphenol-rich extract obtained from chokeberry aronia melanocarpa (michx.) elliot, raspberry rubus idaeus l., bilberry vaccinium myrtillus l. and cranberry vaccinium macrocarpon aiton fruits and its underlying molecular mechanisms were investigated in differentiated 3t3-l1 adipose cells. treatment with t ...	2017	29182628
protein-bound vaccinium fruit polyphenols decrease ige binding to peanut allergens and rbl-2h3 mast cell degranulation in vitro.	peanut allergy is a worldwide health concern. in this study, the natural binding properties of plant-derived polyphenols to proteins was leveraged to produce stable protein-polyphenol complexes comprised of peanut proteins and cranberry (vaccinium macrocarpon ait.) or lowbush blueberry (vaccinium angustifolium ait.) pomace polyphenols. protein-bound and free polyphenols were characterized and quantified by multistep extraction of polyphenols from protein-polyphenol complexes. immunoblotting was ...	2017	28294257
hplc method for measurement of human salivary α-amylase inhibition by aqueous plant extracts.	control of hyperglycemia is an important treatment in metabolic disorders such as type ii diabetes and obesity. α-amylase, as the first enzyme of glucose release from dietary polysaccharides, is a potential target to identify new sources of novel anti-obesity and anti-diabetic drugs. in this work, different herbal extracts as α-amylase inhibitors were studied by measuring the rate of the cleavage of a maltooligomer substrate 2-chloro-4-nitrophenyl-β-d-maltoheptoside. measurement of chromophore c ...	2017	28605974
development of sparganothis sulfureana (lepidoptera: tortricidae) on cranberry cultivars.	sparganothis fruitworm (sparganothis sulfureana clemens) (lepidoptera: tortricidae) is a serious pest of cranberry (vaccinium macrocarpon aiton), a native north american fruit cultivated in northern regions of the united states and southeastern canada. this study assessed antibiosis in several cranberry cultivars commonly grown in wisconsin. five cultivars previously shown to host different levels of populations of s. sulfureana in commercial cranberry were assessed in this study to evaluate the ...	2018	29301287
consumption of plant food supplements in the netherlands.	the use of food supplements containing herbs or other botanical ingredients (plant food supplements, pfs) is on the rise. in some cases, pfs can contain compounds that are toxic and may pose a health risk. to assess the potential health risks, information on the consumption of pfs is required, however, this was lacking for the netherlands. in the current study, the consumption of pfs was investigated for several subgroups in the dutch population, including children. data from the dutch national ...	2018	29184939
advantages of a validated uplc-ms/ms standard addition method for the quantification of a-type dimeric and trimeric proanthocyanidins in cranberry extracts in comparison with well-known quantification methods.	the berries of vaccinium macrocarpon, cranberry, are widely used for the prevention of urinary tract infections. this species contains a-type proanthocyanidins (pacs), which intervene in the initial phase of the development of urinary tract infections by preventing the adherence of escherichia coli by their p-type fimbriae to uroepithelial cells. unfortunately, the existing clinical studies used different cranberry preparations, which were poorly standardized. because of this, the results were h ...	2018	28950214