Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| survey of dirofilaria immitis infection among dogs at fort dix & mcguire afb, new jersey. | 1976 | 1048799 | |
| pulmonary dirofilariasis: another coin lesion. | a 67-year-old woman with a long history of debilitating rheumatoid arthritis developed a peripheral coin lesion in the lower lobe of the left lung. a wedge resection was done and pathologic study revealed noncaseating granuloma secondary to rheumatoid infection with dirofilaria immitis, a nematode. although rare, canine dirofilariasis should be considered in the differential diagnosis of coin lesions. | 1977 | 850826 |
| adult heartworms in arteries and veins of a dog. | a 5-year-old terrier-type dog with a 3-week history of progressive lameness, swelling, and pain in the left hindlimb suddenly became paralyzed in the right hindlimb. because of a poor prognosis, the dog was euthanatized. necropsy revealed mature heartworms (dirofilaria immitis) in the femoral arteries as well as in the right side of the heart and pulmonary arteries. extensive ischemic necrosis in the muscles of the hindlimbs was attributed to occlusion of the femoral arteries by heartworms. | 1977 | 858687 |
| preliminary studies on the transplantation of adult dirofilaria immitis into laboratory rodents. | 1977 | 869615 | |
| evaluation of a polycarbonate filter for the detection of microfilaremia in dogs in central michigan. | several diagnostic techniques were used in determining the prevalence of microfilaremia in 479 dogs entering the holding facility for research animals at michigan state university. the modified knott test and cellulose filter procedures were initially applied, but persistent difficulties with the cellulose filter system prompted evaluation of the use of clear polycarbonate filters. this procedure was found to be equally as sensitive as the modified knott test and more sensitive than the microhem ... | 1977 | 870465 |
| prevalence of dirofilaria immitis infection in dogs from a humane shelter in ohio. | hearts of 500 dogs more than 1 year old from a humane shelter in columbus, oh, were examined for dirofilaria immitis infection. peripheral blood from dogs with worms in the heart was examined for microfilariae. dirofilaria immitis adults were found in 24 (4.8%) hearts. the number of worms in infected hearts were: 19 (1 dog), 6 (2 dogs), 5 (1 dog), 4 (2 dogs), 3 (1 dog), 2 (9 dogs), and 1 (8 dogs). of the 24 infected dogs, 4 had only male worms, 8 had only female worms, and 12 had worms of both s ... | 1977 | 870466 |
| efficacy of levamisole resinate against dirofilaria immitis in dogs. | 1977 | 882096 | |
| dirofilaria immitis recovered from a horse. | 1977 | 893220 | |
| susceptibility of dogs with heartworm disease to hypoxia. | dogs with dirofilaria immitis microfilariae and early radiographic pulmonary artery changes, but without pulmonary hypertension or clinical signs of heartworm disease, were studied. an exaggerated pulmonary hypertensive response was found in these dogs if subjected to 10% inspired oxygen. the mean pulmonary artery pressure of control dogs was increased from base line (prehypoxia control) of 15.8 +/- 2.3 (sem) mm of hg to 20.2 +/- 2.3 during hypoxia, and the mean pulmonary pressure of dogs with h ... | 1977 | 921031 |
| diethylcarbamazine citrate for prevention of heartworm (dirofilaria immitis) in the california sea lion (zalophus californianus). | 1977 | 585265 | |
| dirofilaria immitis from the eye of a dog in arkansas. | 1977 | 592053 | |
| pulmonary dirofilariasis: report of a human case. | dirofilaria immitis (dog heartworm) principally infests canine hosts. however, human pulmonary dirofilariasis is being reported with increasing frequency, and the following case illustrates essential features of the disease. it typically presents as a solitary pulmonary nodule without symptoms and invariably requires pulmonary resection to differentiate it from primary or secondary malignancy. | 1977 | 594944 |
| filaria in the vitreous of the eye of man in peninsular malaysia. | an active worm was seen in the right eye of a 62-year-old man in malaysia. the worm was behind the lens and attached at one end to some vitreous fibers. it was tentatively identified as an immature dirofilaria immitis. there appear to be only five previous authentic reports of filariae in the vitreous. | 1977 | 596511 |
| density gradient separation of lymphocytes, eosinophils, and microfilariae from blood of dogs infected with dirofilaria immitis. | 1977 | 596710 | |
| heartworm heart disease. | 1977 | 602865 | |
| increased pulmonary vascular pressor response to hypoxia in highland dogs. | 1977 | 14334 | |
| distribution of acid phosphatase activity in the larval stages of wuchereria bancrofti, brugia malayi, b. pahangi and dirofilaria immitis in the mosquito. | the histochemical distribution of acid phosphatase in microfilariae and in the larval stages of four mosquito-borne filariae: wuchereria bancrofti, brugia malayi, b. pahangi and dirofilaria immitis was studied using naphthol as-tr-hexazonium technique and light microscopy. accurate differentiation between microfilariae of the four species could be made on the basis of their patterns of acid phosphatase activity. in contrast to microfilariae in the blood, the larval stages in the mosquito exhibit ... | 1977 | 16368 |
| dirofilaria immitis and its potential mosquito vectors in central new york state. | screening of 25,822 dog blood samples indicated approximately a 1% infection rate with dirofilaria immitis. dipetalonema reconditum microfilariae were found in approximately 2% of 1,876 feral dogs examined. laboratory experimentation indicated that 6 of 10 local mosquito species examined allowed successful extrinsic incubation of d immitis. indices of experimental infection indicated aedes triseriatus and anopheles quadrimaculatus were excellent hosts for d immitis, but other factors considered, ... | 1977 | 20828 |
| hexokinase of the adult dog heartworm, dirofilaria immitis. | 1. dirofilaria immitis hexokinase was relatively heat stable and had a ph optimum range between 7.8 and 8.2. 2. mean vmax was 0.40 +/- 0.10 (s.d.) mumole/min/100 mg of worm. 3. mean km values were 0.32 mm for glucose, 0.86 mm for fructose and 0.39 mm for atp. 4. glucose-6-phosphate was not a strong product inhibitor. 5. starch gel electrophoresis demonstrated at least three isozymes. | 1977 | 45524 |
| analysis of serum proteins, using agarose electrophoresis in normal dogs and in dogs naturally infected with dirofilaria immitis. | the electrophoretic pattern of 130 serum samples from clinically normal dogs was evaluated, using agarose as the supporting matrix. the relative mobility of each globulin fraction in relationship to the mobility of albumin was determined in 70 dogs, and nomenclature based on the mobilities (rf values) was proposed. biuret protein determinations were done, and relative and absolute values of each serum protein fraction were determined. changes in the fractions of serum proteins were evaluated in ... | 1977 | 70182 |
| a shock syndrome related to administration of diethylcarbamazine citrate, producing electrocardiographic changes in a dog with microfilariae of dirofilaria immitis. | 1977 | 245205 | |
| sensitivity and specificity of skin reactivity to brugia malayi and dirofilaria immitis antigens in bancroftian and malayan filariasis in the philippines. | saline antigen extracts of microfilariae, adult worms and third-stage larvae of subperiodic brugia malayi maintained in gerbils were prepared for use as skin test reagents. patients were studied on three different islands in the philippines, one endemic for bancroftian filariasis (sorsogon, luzon), another endemic for malayan filariasis (palawan) and the third without endemic filariasis (cebu). a dose-response curve was established initially in patients with bancroftian filariasis: thereafter 1. ... | 1977 | 322516 |
| immunofluorescent reactions with microfilariae: 1. diagnostic evaluation. | microfilariae have been evaluated as antigen for the indirect immunofluorescent test in the diagnosis of filariasis. sonicated, unlike whole, microfilariae present no problems in handling on a slide. the cytoplasmic antigen that is exposed by sonication, unlike the sheath or cuticular antigen, reacts with filariasis sera irrespective of whether or not there is a detectable microfilaraemia. the cytoplasmic antigen of microfilariae of various species was marginally superior to dirofilaria adult wo ... | 1977 | 339419 |
| "a most certaine and true relation of a strange monster or serpent found in the left ventricle of the heart of john pennant, gentleman, of the age of 21 years". | 1977 | 339428 | |
| [the incidence of dirofilaria immitis in dogs of havana city]. | the significance of the knowledge of the incidence of dirofilaria immitis in the dog is emphasized since dirofilariasis is a zoonosis which produce subcutaneous tumors which clinical-etiological diagnosis is very difficult. adult forms are often located in the skin. the percentage of parasitized dogs found in the havana city is reported. one-hundred-and-two necropsies of gadder dogs depicted that 6,86% of them had dirofilaria immitis. results were negative in the remaining 93,13%. | 1977 | 354645 |
| [immunological diagnosis of filariosis in persons returning from tropical countries and in european and indigenous inhabitants of endemic areas (author's transl)]. | serum samples from persons who lived in areas where onchocerciasis occurred or who had filariasis were examined with the complement fixation test and the indirect hemagglutination test for the presence of antibodies against crude extracts from dirofilaria immitis, onchocerca volvulus, dipetalonema viteae, and ascaris suum. the results could be interpreted as follows: 1. the indirect hemagglutination test was more sensitive than the complement fixation test for the demonstration of antibodies in ... | 1977 | 271633 |
| high dipetalonema reconditum microfilarial counts in two dogs. | dipetalonema reconditum microfilarial counts of 509 and 932/ml of blood, respectively, were found in 2 dogs thought to have been infected with dirofilaria immitis. the high counts were attributed to a state of immunosuppression. it was concluded that microfilarial width is a more reliable criterion that microfilarial numbers for the differentiation of d immitis and d reconditum infections. for reliable width measurements, it is necessary to use the modified knott or polycarbonate filter techniqu ... | 1978 | 566740 |
| the prevalence of heartworms (dirofilaria immitis) in dogs from indiana. | 1978 | 569196 | |
| a heated centrifuge for orientation of electron microscope specimens. | 1978 | 364776 | |
| studies on endoparasites of the black bear (ursus americanus) in the southeastern united states. | examination of 53 black bears (ursus americanus) from six states in the southeastern united states revealed at least 17 species of endoparasites, including sarcocystis sp., spirometra mansonoides (spargana), macracanthorhynchus ingens, ancylostoma caninum, arthrocephalus lotoris, baylisascaris transfuga, capillaria aerophila, capillaria putorii, crenosoma sp., cyathospirura sp., dirofilaria immitis, gnathostoma sp., gongylonema pulchrum, microfilariae, molineus barbatus, physaloptera sp. and str ... | 1978 | 418189 |
| immunodiagnosis of parasitic zoonoses: comparative efficacy of three immunofluorescence tests using antigens purified by affinity chromatography. | three immunofluorescent antibody assays were developed during this study: the direct (dfat) and indirect (ifat) fluorescent antibody tests using frozen worm sections, and the cyanogen bromide indirect fluorescent antibody test (cnbr-ifat) using helminth antigens purified by affinity chromatography bound on to commercially prepared cnbr-sepharose 4b beads. purified antigens used in the cnbr-ifat gave greater specificity and sensitivity than either the dfat or ifat. dirofilaria immitis, toxocara c ... | 1978 | 354114 |
| presumed dirofilaria immitis infections in natural mosquito populations of connecticut. | 1978 | 32395 | |
| dirofilaria immitis: effect on the longevity of aedes trivittatus. | 1978 | 627272 | |
| cuticular morphology of five species of dirofilaria: a scanning electron microscope study. | cuticular markings of five species of dirofilaria were examined by sem. variations in the patterns on the en face view were observed among the species. transverse striations were observed on the cuticles of all five species, but longitudinal ridges were lacking on dirofilaria immitis, the type species of the subgenus dirofilaria. they were present on the other four species, dirofilaria repens, dirofilaria tenuis, dirofilaria corynodes, and dirofilaria magnilarvatum, members of the subgenus nocht ... | 1978 | 627947 |
| dirofilaria immitis: experimental infections in the ferret (mustela putorius furo). | the ferret, mustela putorius furo, was found to be susceptible to dirofilaria immitis infection when exposed to low (14) or high (280-420) numbers of infective larvae harvested from aedes aegypti. eight ferrets (half of them cortisonized) were inoculated subcutaneously with 14 larvae each. all of them were subsequently found to harbor d. immitis in the heart, and all but one of them had worms of both sexes. six of these ferrets were examined for microfilaremia at 31 to 35 weeks after inoculation ... | 1978 | 627949 |
| laboratory observations on the insusceptibility of raccoons to dirofilaria immitis. | two raccoons, procyon lotor, were exposed to dirofilaria immitis by subcutaneous injection of infective third stage larvae obtained from experimentally-infected aedes trivittatus. nematodes were not recovered from either raccoon when examined at necropsy 223 and 254 days postexposure. large numbers of adult d. immitis were found in six dogs used as controls. these data indicate that raccoons cannot support the development of d. immitis. | 1978 | 633513 |
| dirofilaria immitis: a cause of human intra-ocular infection. | 1978 | 689747 | |
| heartworm infected dogs in the netherlands. | heartworm infected small animal patients are seldom seen in the netherlands, because the parasite's life cycle cannot be completed in this climate. we report here four cases of the disease in dogs brought to the netherlands from endemic heartworm areas. the initial diagnosis was based upon this knowledge and clinical signs (low exercise tolerance and coughing). the diagnosis was confirmed by the radiographic finding of variable pulmonary artery enlargement, the electrocardiographic finding of ri ... | 1978 | 705753 |
| rapid decrease of precipitating and reaginic antibodies in dirofilaria immitis-infected dogs which develop severe adverse reactions following treatment with diethylcarbamazine. | dirofilaria immitis-infected dogs were treated with diethylcarbamazine. measurement of the level of igg precipitating antibody was carried out by counterimmunoelectrophoresis and that of ige by passive cutaneous anaphylaxis in pre-treatment and post-treatment serum samples. in dogs showing severe to moderate adverse reactions to the drug there were pronounced decreases of both antibodies to a "metabolic" antigen prepared from the medium in which adult female worms had been incubated. these antib ... | 1978 | 727319 |
| trial of avermectin b1a, mebendazole and melarsoprol against pre-cardiac dirofilaria immitis in the ferret (mustela putorius furo). | avermectin b1a was found active against the pre-cardiac stage of dirofilaria immitis in ferrets. the drug was given orally, at 0.2 mg/kg, on days 38--42 of infection. at necropsy, 5 1/2 months after inoculation, worms were almost totally absent from the hearts of these ferrets. the efficacy of melarsoprol against developing dirofilaria, which has been demonstrated in dogs by other workers, was demonstrated in ferrets given oral doses, at 100 mg/kg, on days 38--42 of infection. the reported effic ... | 1978 | 739297 |
| [a case of pulmonary dirofilariasis presenting pulmonary infarction caused by dirofilaria immitis (author's transl)]. | 1978 | 739699 | |
| cell mediated and humoral immune response in tropical eosinophilia. | 1978 | 744632 | |
| efficacy of avermectins against dirofilaria immitis in dogs. | 1978 | 752054 | |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 13-1979. | 1979 | 763304 | |
| observations on the early death experienced by dirofilaria immitis-infected mosquitoes (diptera: culicidae). | 1979 | 35614 | |
| specific allergic sensitsation to filarial antigens in tropical eosinophilia syndrome. | reaginic antibodies to antigens from the human filarial parasites wuchereria bancrofti and brugia malayi and the animal parasite dirofilaria immitis were studied by histamine release from basophils in 7 patients with tropical eosinophilia (t.e.) and 18 patients with other manifestations of filarial infection (lymphatic changes or symptomless microfilaraemia). all the patients had antibodies to all three filariae but t.e. patients were more highly sensitised. t.e. patients responded more to antig ... | 1979 | 86883 |
| intraarticular microfilariae in laboratory animals. | 1979 | 114182 | |
| inhibition of dirofilaria immitis in gregarine-infected aedes aegypti: preliminary observations. | 1979 | 115926 | |
| glycolytic end products of the adult dog heartworm, dirofilaria immitis. | 1. adult dog heartworms remained alive and motile for 24 hr without oxygen present and with only glucose available as a substrate. 2. lactate accounted for 55% of the carbon from the 1-14c-glucose utilized in 1 hr and 14co2 for 1.9%. 3. only traces of 14c were found in glycogen and no net accumulation of acetate was demonstrated. 4. dirofilaria immitis resembles litomosoides carinii in the percent of utilized glucose appearing as lactate but is more akin to brugia pahangi and dipetalonema viteae ... | 1979 | 122581 |
| incidence of heartworm (dirofilaria immitis) infection in memphis, tennessee. | 1979 | 257970 | |
| inhibition of lactate dehydrogenase activity from dirofilaria immitis by suramin. | lactate dehydrogenase from adult d. immitis was partially purified and characterized. the molecular weight of the enzyme was determined to be 130 000. the specific activity of the lactate dehydrogenase was 4.1 u/mg in the direction of nadh-oxidation and 0.38 u/mg protein in the direction of nad-reduction. the michaelis constants were determined to be 0.028 mm and 0.9 mm for nadh and nad, respectively. suramin was found to be a potent inhibitor of the lactate dehydrogenase activity. the inhibitio ... | 1979 | 231858 |
| survey for dirofilaria immitis in mecklenburg county, north carolina. | 1979 | 438038 | |
| the effects of various carbohydrate diets on aedes aegypti infected with dirofilaria immitis. | 1979 | 438527 | |
| pulmonary lesions due to dirofilaria immitis (dog heartworm). report of four cases with radiologic findings. | chest radiographs of 4 patients with dirofilaria immitis (dog heartworm) revealed solitary, small, peripheral, noncalcified nodular lesions. the pulmonary lesions were apparently produced secondary to lodging of the parasite in peripheral pulmonary vessels. none of the patients had symptoms referable to the heartworm lesions. needle aspiration in 2 patients revealed a nonspecific inflammatory lesion. | 1979 | 441308 |
| brugia pahangi and dirofilaria immitis: experimental infections in the ferret, mustela putorius furo. | 1979 | 446585 | |
| immunological and physicochemical properties of a highly purified allergen from dirofilaria immitis. | allergen in crude extract of dirofilaria immitis was purified and separated from igg-inducing antigens by a combination of deae-sephadex a-50 chromatography, sephadex g-200 gel filtration and starch gel zone electrophoresis. the purified preparation was proved to be one protein band by sodium dodecyl sulfate polyacrylamide gel (sds-gel) electrophoresis and one precipitin arc by immunodiffusion. the molecular weight of the purified allergen was estimated to be approximately 20,000 by gel filtrati ... | 1979 | 468388 |
| nodular skin disease associated with dirofilaria immitis infection in the dog. | three dogs with dirofilariasis had a dermatologic syndrome, characterized by pruritus and multifocal nodules which tended to ulcerate. the cutaneous nodules revealed angiocentric pyogranulomatous inflammation with variable numbers of eosinophils. microfilariae were often present in the blood vessels surrounded by the pyogranulomatous process. therapy for dirofilariasis resulted in complete resolution of the dermatitis. | 1979 | 477322 |
| dirofilaria immitis: cell-mediated and humoral immune responses in experimentally-infected dogs. | 1979 | 489233 | |
| culture systems for the maintenance and development of microfilariae. | 1979 | 496468 | |
| dirofilaria in the abdominal cavity of a man in japan. | a case of human dirofilariasis of the abdominal cavity is reported from japan. the patient, a 74-year-old man, died of liver cancer; postmortem examination revealed a granulomatous mass on the mesentery. in histologic sections there were cross-sections of a mature female nematode identified as a dirofilaria. the cuticle had a smooth surface and consisted of four distinct layers. the inner cuticular layer had internal lateral longitudinal ridges, and the musculature of the body wall was of the hi ... | 1979 | 507286 |
| efficacy of avermectin b1a against microfilariae of dirofilaria immitis. | avermectin b1a given at a dose level of 0.05 or 0.1 mg/kg of body weight caused rapid removal of dirofilaria immitis microfilariae from the blood of dogs with heartworm infections. if the adult worms were also killed with an arsenical (melarsoprol), the removal of microfilariae was permanent. | 1979 | 507489 |
| microfilariae in the ejaculate of a dog. | 1979 | 514248 | |
| dirofilaria immitis infection in foxes and coyotes in indiana. | between october 1976 and january 1977, carcasses or hearts and lungs from 202 wild foxes and coyotes in indiana were collected to determine the prevalence of dirofilaria immitis infection. three of 113 (2.7%) red foxes (vulpes fulva), 3 of 81 (3.7%) gray foxes (urocyon cinereoargenteus), and 1 of 8 (12.5%) coyotes (canis latrans) were infected with d immitis. an average of 5 worms (range, 1 to 10) were recovered from foxes and 11 worms were recovered from the coyote. worms from the coyote were o ... | 1979 | 521369 |
| scintigraphic evaluation of pulmonary perfusion in dogs experimentally infected with dirofilaria immitis. | pulmonary arterial perfusion was evaluated by perfusion lung scans in ten dogs experimentally infected with heartworm. after larval inoculation, scans were done once a month for 11 months. in 8 of 10 dogs, pulmonary arterial perfusion deficits were detected. the perfusion deficits involved the left cranial, right cranial, and right caudal lung lobes. generally, there was a poor correlation between vascular abnormalities detected on the survey thoracic radiographs and the perfusion deficits detec ... | 1979 | 525864 |
| the effectiveness of levamisole hydrochloride in the treatment of adult dirofilaria immitis. | dogs infected with d. immitis were treated with oral levamisole hydrochloride at various dose rates over different durations. clinical toxicity, haematological and biochemical parameters, body weight and food intake were recorded and filarial mortality estimated at autopsy. all filariae were dead in dogs treated at 10 mg/kg body weight twice daily (12 hourly) for 14 days, with minimal clinical toxicity being seen during the treatment period. | 1979 | 543826 |
| indirect fluorescent antibody test in occult dirofilariasis. | indirect fluorescent antibody titers to dirofilaria immitis microfilaria (ifa-mf) and peripheral eosinophilia were recorded from 15 to 52 months in ten experimentally infected dogs with occult dirofilariasis (heartworm infection without microfilaremia). five dogs which were experimentally sensitized with d immitis microfilaria did not exhibit microfilaremia after inoculation with infective-stage larvae. in three other dogs, microfilaremia suddenly ceased after 4 to 7 months. in these three dogs, ... | 1979 | 382922 |
| distribution and diagnosis of dirofilariasis and toxocariasis in australia. | 1979 | 391207 | |
| glycerol metabolism in the adult dog heartworm, dirofilaria immitis. | 1. when adult dirofilaria immitis were incubated up to 60 min in a medium containing physiological concentrations of glycerol and glucose, the mean amount of free glycerol present did not change significantly. 2. [14c]2-glycerol disappeared from media in which 1 g heartworms were incubated at a linear rate of about 0.7 mumol/hr/g during the first hour. 3. 85-95% of the radioactivity in the folch extract remained in the aqueous phase. 4. phosphoglycerides and diacylglycerols accounted for better ... | 1979 | 318317 |
| lipid synthesis in the adult dog heartworm, dirofilaria immitis. | 1. incorporation studies with three labelled substrates--[14c]2-glycerol, [14c]1-acetate and [14c]1-oleic acid--demonstrated that adult dog heartworms can synthesize all classes of complex lipids present, including free cholesterol. 2. diacylglycerols and phosphoglycerides were most rapidly labelled regardless of the precursor employed. 3. 14c from glycerol was found in the aqueous phase of saponified lipids, whereas that from oleic acid was in the fatty acid portion. 4. tag from acetate was pre ... | 1979 | 318318 |
| intradermal reactivity of excretory and secretory products of onchocercal microfilariae. | the intradermal reactivity of excretory and secretory (es) products derived from the in vitro cultivation of onchocercal microfilariae was evaluated. the es products from onchocerca volvulus were highly sensitive in the detection of active onchocerciasis in both liberian and guatemalan subjects. a low level of cross-reactivity occurred in patients with loaisis and in dogs with dipetalonema reconditum, but not in dogs with dirofilaria immitis. es products from o. gutturosa evoked reactions in gua ... | 1980 | 6160775 |
| animal filarial antigens in serological test for human filariasis. | 1980 | 6164103 | |
| subcutaneous dirofilariasis in nebraska. | dirofilaria immitis infection in dogs is an increasing problem throughout much of the united states and is no longer limited to the south. vector mosquitos are present and transmission may occur during the summer months throughout the southern, eastern, and midwestern states. in addition to pulmonary nodules, d immitis and related species cause symptomatic subcutaneous nodules. physicians should be alert to this differential diagnostic possibility. | 1980 | 6101303 |
| folate metabolism in filariae. enzymes associated with 5,10-methenyltetrahydrofolate and 10-formyltetrahydrofolate. | adult dirofilaria immitis and brugia pahangi were found to possess the following folate-related enzymes that catalyze the formation of 5,10-methenyltetrahydrofolate (methenylfh4) or 10-formylfh4 (f10fh4): f10fh4 synthetase, methenylfh4 cyclohydrolase, f5fh4 cyclodehydrase, and a bifunctional complex composed of formiminoglutamate: fh4 formiminotransferase and 5-fomiminofh4 cyclodeaminase. the properties of these filarial enzymes were generally similar to those of their counterparts from inverteb ... | 1980 | 6967110 |
| folate metabolism in filariae: enzymes associated with 5,10-methylenetetrahydrofolate. | adult brugia pahangi and dirofilaria immitis were found to possess the following four enzymes that are associated with the cofactor 5,10-methylenetetrahydrofolate (ch2fh4): serine hydroxymethyltransferase, thymidylate synthetase, ch2fh4 dehydrogenase, and ch2fh4 reductase. the properties of the isoenzymes from the two filariae were virtually indistinguishable, except that diethylcarbamazine inhibited ch2fh4 reductase from b. pahangi 50% at 10 mum, but did not not affect the isoenzyme from d. imm ... | 1980 | 6988563 |
| immediate and delayed hypersensitivity skin test responses to the dirofilaria immitis filarial skin test (sawada) antigen in wuchereria bancrofti filariasis. | in order to assess the immunodiagnostic utility of fst skin test antigen purified from dirofilaria immitis, skin test responses were analyzed in 177 inhabitants of a south pacific island hyperendemic for wuchereria bancrofti filariasis. although the distribution of immediate hypersensitivity skin test responses was similar to those found in other filarial endemic populations, individual immediate skin test reactions lacked the sensitivity and specificity to identify those with microfilaremia or ... | 1980 | 7001936 |
| on the longevity and behaviour of microfilariae of wuchereria bancrofti, brugia pahangi and dirofilaria immitis transfused to laboratory rodents. | microfilariae of wuchereria bancrofti and brugia pahangi, which were inoculated into meriones unguiculatus and mastomys natalensis respectively, were found in the peripheral blood of the rodents until the ninth day after infection, but no microfilarial periodicity was observed. microfilariae of w. bancrofti disappeared much faster from the peripheral blood of jirds after reinfection than after the first inoculation. microfilariae of dirofilaria immitis inoculated into m. natalensis and laborator ... | 1980 | 7003830 |
| suppression of maturation of dirofilaria immitis in mustela putorius furo by single dose of ivermectin. | 1980 | 6893467 | |
| dirofilaria immitis: a zoonosis of clinical concern. | dirofilaria immitis, the dog heartworm, is responsible for an endemic zoonosis in the southeastern united states. the nematode is capable of infesting the lungs of man, causing pulmonary nodules. the epidemiologic, morphologic, and clinical features of d immitis infestation are discussed. | 1980 | 7190328 |
| survey of heartworm disease (dirofilaria immitis) in the kanawha valley, west virginia. | 1980 | 6901433 | |
| zoonotic implications of cats and dogs in filarial transmission in peninsular malaysia. | filarial infections in 447 cats and 68 dogs from six endemic areas of human filariasis in peninsular malaysia were studied as part of the study on the zoonotic transmission of subperiodic brugia malayi infection. 20.6% of cats and 57.4% of dogs had filarial infections. cats were infected with subperiodic b. malayi, b. pahangi, dirofilaria repens and d. immitis. dogs were infected with b. pahangi and d. immitis. 6.9% of the cats had subperiodic b. malayi infection. the zoonotic implications of th ... | 1980 | 7210162 |
| dirofilaria immitis in west central colorado. | 1980 | 7218108 | |
| neostigmine-responsive weakness and glomerulonephritis associated with heartworm dirofilaria immitis infestation in a dog. | microfilariae of dirofilaria immitis were found in blood smears of a dalmation which showed clinical signs of muscle weakness and membranous glomerulonephritis. the muscle weakness responded to treatment with neostigmine and the microfilariae disappeared after treatment with levamisole. | 1980 | 7241497 |
| in vitro cultivation of microfilaria of dirofilaria immitis. | 1980 | 7310103 | |
| field isolations of dirofilaria from mosquitoes in alabama. | field collections of mosquitoes were made april-september 1977 and 1978 in the immediate vicinity of a hunting-dog kennel where the dogs had a chronic history of heartworm infection. among 19 mosquito species taken in light-trap collections, only aedes sticticus, ae. vexans, and anopheles punctipennis were found infected with what were presumed to be d. immitis larvae. based on natural infection rates and the relative abundance of these three host species, an. punctipennis and ae. sticticus appe ... | 1980 | 7365629 |
| dirofilariasis in a cat. | 1980 | 7366578 | |
| uptake of amino acids and glucose by microfilariae of dirofilaria immitis in vitro. | the uptake of amino acids and glucose by microfilariae of dirofilaria immitis maintained for 8 days in vitro was studied. the quantity of glutamic acid, histidine, lysine, alanine, tryptophan, and cystine in the medium did not change. isoleucine, serine, valine, phenylalanine, tyrosine, methionine, and cystathionine decreased slightly; both asparatic acid and leucine decreased considerably. glutamine, threonine, and proline decreased markedly, while glycine increased to some extent. ornithine in ... | 1980 | 7369440 |
| cardiopulmonary function in the dog with dirofilaria immitis infection: during infection and after treatment. | cardiopulmonary function in seven beagles (under pentobarbital anesthesia) was determined before they were inoculated with dirofilaria immitis larvae, at 6 and at 12 months after 50 infective larvae were inoculated, and at 7 and 12 months after adulticide and microfilaricide treatment was begun. pulmonary hypertension (26.4 mm of hg +/- 3.5 (sd)) was present at 12 months after the dogs were inoculated, as compared with base-line pulmonary arterial pressure (16.0 mm of hg +/- 2.4), and was resolv ... | 1980 | 7369604 |
| acid phosphatase activity demonstrated in the nematodes, dirofilaria immitis and angiostrongylus cantonensis with special reference to the characters and distribution. | acid phosphatase activity was demonstrated in the intact blood nematodes, dirofilaria immitis and angiostrongylus cantonensis. biochemical studies on acid phosphatase, using intact females and whole worm, body-wall and visceral homogenates were undertaken to clarify the characteristics and the distribution of the enzyme. in d. immitis, high acid phosphatase activity was observed at ph 3.8--5.8 and in a. cantonensis, at ph 4.5--6.0. molybdate, fluoride, copper and zinc ions and l(+)-tartate were ... | 1980 | 7383707 |
| fine structure and cytochemical evidence for the presence of polysaccharide surface coat of dirofilaria immitis microfilariae. | 1980 | 7409978 | |
| coyotes and canine heartworm in california. | adult dirofilaria immitis were found in the hearts of 43 of 115 coyotes (canis latrans) trapped within a 50 km radius of the el dorado county seat. of mature coyotes, 45% were positive, with worm numbers averaging 9.0 in females and 16.2 in males. d. immitis microfilariae occurred in the peripheral blood and in lung smears. microfilariae of dipetalonema reconditum were present in 14 of the coyotes examined (12%). several coyotes showed enlarged hearts with gross pathological changes. | 1980 | 7431518 |
| occurrence of (dirofilaria immitis) in gray fox (urocyon cinereoargenteus) in alabama and georgia. | the occurrence of dirofilaria immitis in gray fox (urocyon cineroargenteus) was determined by gross examination, blood samples, and filtered tissue sediments in a sampling of 149 gray foxes taken from alabama and georgia during the 1977-78 trapping season. microfilariae were not found in blood samples obtained from 24 of these gray foxes. three of 82 male foxes (3.7%) and 1 of 67 female foxes (1.5%) were infected with heartworm. d. immitis rate of infection was 1 of 19 (5.3%) and 3 of 130 (2.3%) ... | 1980 | 7431520 |
| dirofilaria immitis in red foxes in illinois. | dirofilaria immitis was found in 8 of 225 (3.6%) red foxes (vulpes vulpes) collected from fur buyers and trappers in bond, clinton, dekalb, edgar, ford, jasper, moultrie, and richland counties, illinois. infections ranged from 1 to 23 nematodes per fox. the finding of d. immitis in red foxes represents a new host record for the state. | 1980 | 7431521 |
| pulmonary vascular response during phases of canine heartworm disease: scanning electron microscopic study. | pulmonary arteries and veins of 14 dogs in phases of heartworm disease (dirofilaria immitis infection) were examined by scanning electron microscopy. two dogs were infected with d immitis microfilaria only, whereas 12 dogs were infected with adult d immitis. seven of the dogs infected with adult worms were untreated. two of these 7 dogs had natural infections of unknown duration introduced by mosquito bite, whereas 5 were experimentally infected for 30 days. the remaining five dogs were experime ... | 1980 | 7436103 |
| intimal lesions of the pulmonary artery in dogs with experimental dirofilariasis. | microscopic examination, particularly by scanning electron microscopy, of the tunica intima of the pulmonary arteries of dogs experimentally infected with a known number of larvae of dirofilaria immitis revealed various numbers and shapes of intimal thickenings. the number and morphology of these thickenings were related to the degree of infection. at 11 months after infection, dogs having adult worm populations of 8 to 21 worms had scattered discrete intimal lesions, whereas in dogs with 41 to ... | 1980 | 7436106 |
| specific depression of cell-mediated immunity in malayan filariasis. | the possible depression of cell-mediated immunity by long-term brugia malayi infection in jirds (meriones unguiculatus) was investigated. different groups of infected jirds were sensitized with dinitrofluorobenzene, sheep red blood cells, dirofilaria immitis adult antigens and b. malayi adult antigens. the 24-hour delayed type hypersensitivity skin response to testing with antigen was measured as an in vivo correlate of cell-mediated immunity. the delayed-type hypersensitivity responses to dinit ... | 1980 | 7445050 |
| natural transmission of dirofilaria immitis by aedes vexans. | aedes vexans mosquitoes were reared in the laboratory from field-collected fourth instar larvae. mosquitoes were allowed to feed on dogs which were infected with dirofilaria immitis and then the mosquitoes were housed in an environmental chamber with an ambient air temperature of approximately 26 c and a relative humidity of approximately 80%. incandescent lighting was used to simulate daylight. on the 17th, 19th, 21st, and 28th day after their infected blood meal, the mosquitoes were allowed to ... | 1980 | 7447120 |
| heartworm removal from a limb of a dog. | 1980 | 7451305 | |
| the genetic basis of susceptibility to infection with dirofilaria immitis in aedes aegypti. | 1980 | 7458468 | |
| efficacy of ivermectin against dirofilaria immitis larvae in dogs 31, 60, and 90 days after injection. | ivermectin, given as a single oral dose of 0.05 mg/kg, prevented the maturation of dirofilaria immitis in dogs if given at 31 or 60 days after infection. when treatment was delayed 90 days after injection, maturation of worms occurred in 3 of 5 dogs. | 1980 | 6894222 |
| acute response of pulmonary blood flow and right ventricular function to dirofilaria immitis adults and microfilaria. | pulmonary arterial pressures, right ventricular pressures, and right ventricular force of contraction (max dp/dt) were measured before and after the surgical addition of dirofilaria immitis adults and microfilaria. six adult anesthetized and heparinized dogs were studied during thoracotomy to compare these pressure measurements with left caudal pulmonary arterial flow. diversion of pulmonary flow was performed to obtain incremental increases in pulmonary flow through the left caudal lobar artery ... | 1980 | 7369595 |