Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [comparative precipitation studies between the highly-virulent virus of european swine fever, swine-fever-virus split products and precipitating swine-fever antigens from the organs of swine-fever infected pigs]. | 1977 | 414484 | |
| [auricular fibrillation with ventricular tachycardia. surgical section of a left lateral bundle of kent]. | the authors report the case of a man of 22 years, with no previous cardiac history, in whom a wolff-parkinson-white syndrome was discovered during the course of this first episode of atrial fibrillation with a ventricular rate of 300-350/mn; investigation (vecto-cardiogram, intra-cavitory ecg) showed the presence of a short circuit of the kent type, with a high permeability, and localised in the left lateral position; this was confirmed by pericardial cartography. after the surgical division of ... | 1977 | 414674 |
| studies on the pathogenesis of rickettsia rickettsii in the dog: clinical and clinicopathologic changes of experimental infection. | beagle dogs inoculated with the agent of rocky mountain spotted fever, rickettsia rickettsii, developed a clinical syndrome that extended from febrile exanthema to death and appeared to be dose related. infected dogs were anorectic and lethargic and developed cutaneous lesions characteristic of rocky mountain spotted fever, including petechia, ecchymosis, edema, and necrosis. hematologic changes after inoculation included anemia, leukopenia proceeding to leukocytosis, and thrombocytopenia. chang ... | 1977 | 879582 |
| listeria monocytogenes meningitis: case report. | a case of listeria monocytogenes septicaemia with meningitis is described. predisposing factors in this case included chronic liver disease, diabetes mellitus and liver malignancy. the infection responded poorly to ampicillin. | 1977 | 415268 |
| carotid endarterectomy in great britain and ireland: trends and current practice. | of 309 questionnaires on carotid endarterectomy sent to all surgeons in great britain and ireland who might use this technique, 298 (96 per cent) were returned. in all, 110 (37 per cent) of 298 surgeons performed at least one carotid endarterectomy in 1989; 67 performed less than 10 and 43 greater than 10. in total, these 110 surgeons performed 1417 operations in 1989, a situation that has changed little over 5 years since the previous survey. transient ischaemic attack and minor stroke remain t ... | 1977 | 2032096 |
| radiological evaluation of anal fistulae: a prospective study of fistulograms. | a review of 33 fistulograms in a four-year study is presented. four types of communicating tracts have emerged: single (58%), branched (18%), fistulous abscess (15%) and compound (9%). this classification has formed the basis of selection of operative treatment in all the cases. diminished lumbo-sacral angle was also found in most of the anal fistula cases and this establishes a possible association between the pathology of anal fistula and the low back syndrome. | 1977 | 421419 |
| bilateral mandibular supernumerary bicuspids. | 1978 | 275194 | |
| incidence of ruptured chordae tendineae in the mitral valvular prolapse syndrome: an echocardiographic study. | echocardiographic studies were performed in 190 consecutive patients with mitral valvular prolapse. all patients had either midsystolic posterior motion of the mitral valve or holosystolic hammock-like movement of the valve in systole. thirteen patients (7 percent) were noted to have ruptured chordae tendineae. in four patients, a combination of abnormalities was observed. five patients had clinical and bacteriologic evidence of infective endocarditis, two of whom had severe intractable pulmonar ... | 1978 | 421575 |
| [the psychodynamics of schizophrenia. 2. the current interpretation of the deficit theory, psychodynamic concepts outside psychoanalytic studies, theories on interpersonal dynamics, resp. family dynamics]. | 1978 | 422098 | |
| [cellular composition of the lymph nodes of monkeys (rhesus macaque) under normal and experimental conditions]. | by means of mathematical methods, quantitative and qualitative changes were studied in different structural components of the mesenteric (ileocecal) lymph nodes in normal monkeys (macaca rhesus) and under per os administration of salmonella typhi murium, streptomycin-dependent. cellular composition was calculated in the cortical plateau, cortical (lymphoid) cords and in follicules. average percent of every cell type was determined. vaccine administration, was stated to inhibit cytopoiesis in the ... | 1978 | 415703 |
| rocky mountain spotted fever caused by blood transfusion. | transfusion of 500 ml of blood, contributed by a donor three days before the onset of rocky mountain spotted fever and refrigerated for nine days, caused this disease in the recipient. the blood donor died of rocky mountain spotted fever after six days; rickettsia were identified in various tissues by immunofluorescence techniques. the recipient of the blood became mildly ill and recovered fully; specific antibiotic treatment was initiated on the fourth day of illness. diagnosis of rocky mountai ... | 1978 | 418193 |
| myocardial involvement in rocky mountain spotted fever. | rocky mountain spotted fever (rmsf), an acute febrile exanthematous illness caused by rickettsia rickettsii and transmitted by ticks, is endemic in the southern atlantic states. this report is based on the clinical and pathological findings of myocardial involvement in 16 children who died with severe rmsf. all 16 children had myocardial lesions to some degree, but it was not believed that these could be evaluated in terms of cardiac function and death in the face of the usual peripheral vascula ... | 1978 | 580868 |
| complement in cystic fibrosis. | complement components c3, c4, and c3a were estimated in 30 patients with cystic fibrosis aged 1 to 21 years (m:f = 16:14) and were compared with results in 40 healthy, age-matched subjects. the influences of the clinical score, sputum microbiology, and the patients' sex were also investigated. in contrast to most previous communications, this paper shows that, compared to the control group, a significant decrease of c3 (p less than 0.001) and c4 (p less than 0.02) was observed whereas c3a levels ... | 1978 | 414916 |
| comparative electrophoresis of spotted fever group rickettsial proteins. | 1978 | 415197 | |
| anti-epidermal-cell-surface pemphigus antibody detaches viable epidermal cells from culture plates by activation of proteinase. | immunoglobulin from pemphigus patients binds to the surface of mouse epidermal cells in culture. cells incubated with the pemphigus antibody are easily detached from culture plates whereas cells incubated with serum from normal patients remain on the plate. pemphigus antibody-mediated cell detachment is blocked by the addition of the proteinase inhibitors soybean trypsin inhibitor and alpha2-macroglobulin to the culture media. detachable cells are viable, and activation of the complement cascade ... | 1978 | 272663 |
| melatonin secretion decreases during the proestrous stage of the rat estrous cycle. | urine was collected from rats during 12 consecutive daily dark periods and assayed for melatonin and norepinephrine; the phase of the vaginal estrous cycle associated with each urine sample was determined from daily vaginal smears. the proestrous phase of the estrous cycle was consistently associated with significant reductions in the excretions of both compounds. the level of melatonin in any urine sample tended to vary as a function of its norepinephrine content; however, the slope of the curv ... | 1978 | 272672 |
| anticomplementarity in complement-fixation test with soluble antigens of the spotted fever group rickettsiae. | anticomplementarity occurring in the complement-fixation (cf) test with soluble antigens of rickettsiae of the spotted fever (sf) group is caused by interaction of soluble antigens with guinea pig sera serving as the source of complement. the serum factor responsible for anticomplementarity is thermostable and cannot be removed by treatment of guinea pig serum with co2 or nitrogen. an adverse effect of such serum was also observed upon its mixing with other guinea pig sera lacking anticomplement ... | 1978 | 219638 |
| rna and protein of ibaraki virus. | 1978 | 232730 | |
| activation of the kallikrein-kinin system in rocky mountain spotted fever. | activation of the kallikrein-kinin system, as indicated by increased plasma kallikrein and depleted plasma kininogen, prekallikrein, and kallikrein inhibitor, was observed in five patients with rocky mountain spotted fever. four of the patients had petechial rashes characteristic of vasculitis. three patients had alterations in coagulation consistent with disseminated intravascular coagulation, although no hemorrhagic syndrome was found. our data, along with the known physiologic actions of kini ... | 1978 | 307354 |
| cytotoxic activities of normal cultured human t cells. | normal human t cells grown in continued cultures in medium containing conditioned medium (cm) from pha-stimulated lymphocytes were studied for their ability to manifest three known forms of cell-mediated cytotoxicity: lectin-induced cellular cytotoxicity (licc), natural killer cell (nk) activity, and antibody-dependent cellular cytotoxicity (adcc). the cultured t cells (ctc) were very effective mediators of licc, being cytotoxic even at very low attacker-target cell ratios in the presence of dif ... | 1978 | 308961 |
| fc-receptors on human t lymphocytes. i. transition of tgamma to tmu cells. | 1978 | 308968 | |
| human bone marrow colony formation in diffusion chambers. normal values. | 1978 | 340240 | |
| a method for specific diagnosis of rocky mountain spotted fever on fixed, paraffin-embedded tissue by immunofluorescence. | for specific demonstration of rickettsia rickettsii in fixed, paraffin-embedded tissues, the technique of trypsin digestion of deparaffinized, rehydrated sections was investigated. it was determined that 3.5 hr of digestion was optimal for achieving discrete, bright, green immunofluorescence of rickettsiae. at autopsy kidneys from seven of 10 cases of probably rocky mountain spotted fever contained structures that were specifically stained and that had the size and shape of rickettsiae. these st ... | 1978 | 342642 |
| fatal viscerotropic rocky mountain spotted fever. report of a case diagnosed by immunofluorescence. | a case of fatal viscerotropic rocky mountain spotted fever with virtual absence of cutaneous lesions was diagnosed at autopsy by specific immunofluorescent demonstration of rickettsia rickettsii in spleen, kidney, epididymis and skin. the clinical presentation was that of insidious onset of fever, renal failure, hypotension, hyponatremia and obtundation over a 10 day period. the patient had respiratory insufficiency, hypocalcemia, increases in creatinine phosphokinase (cpk), serum glutamic oxalo ... | 1978 | 345805 |
| intestinal apoproteins during fat absorption. | to compare the roles of apolipoprotein (apo) a-i, b, and e (or arginine-rich apoprotein, arp) in the intracellular production of intestinal chylomicrons (and/or vldl), these apoproteins were localized in rat intestinal mucosa by the light microscope method of indirect immunofluorescence. in addition, tissue levels of apoa-i and apob were measured during fat absorption by radioimmunoassay. antisera were produced using apoa-i isolated from rat plasma high density lipoprotein, and apob and arp from ... | 1978 | 350901 |
| initial clinical evaluation of a new rocky mountain spotted fever vaccine of tissue culture origin. | currently available rocky mountain spotted fever (rmsf) vaccines are relatively ineffective in preventing infections in humans and contain considerable amounts of contaminating egg protein. a new formalin-inactivated vaccine was prepared by sucrose density gradient centrifugation of the sheila smith strain of rickettsia rickettsii grown in chick embryo cell tissue culture. the new product has greater protective immunogenicity in rheusus monkeys and guinea pigs than commercial vaccines. six volun ... | 1978 | 355580 |
| antigen-induced neutrophil chemotactic activity in man. correlation with bronchospasm and inhibition by disodium cromoglycate. | we have previously reported increased neutrophil chemotactic activity in sera obtained after positive antigen inhalation responses in atopic subjects. this report describes the kinetics of appearance of this serum activity and the effects of antigen dose and disodium cromoglycate pretreatment on the response in 10 ragweed-sensitive subjects. significantly increased chemotactic activity was present as early as 1 min, peaked at 10 min, and persisted through 24 hr after inhalation of antigen. the i ... | 1978 | 98551 |
| alterations of body fluid compartments and distribution of tissue water and electrolytes in rhesus monkeys with rocky mountain spotted fever. | chair-restrained rhesus monkeys (macaca mulatta) were inoculated subcutaneously with 10(2)--10(3) plaque-forming units of virulent rickettsia rickettsii. the latent period for fever and rickettsemia was three to four days; death occurred six to eight days after infection. total circulatory electrolyte levels and fluid volumes, including plasma, red blood cell, true circulatory blood, and extracellular fluid, increased. the expansion of the extracellular and plasma volumes resembled findings repo ... | 1978 | 98595 |
| antibacterial functions of macrophages in experimental protein-calorie malnutrition. i. description of the model, morphologic observations, and macrophage surface igg receptors. | an experimental protein-calorie malnutrition was produced in weanling sprague-dawley rats. the model resembles human malnutrition with respect to weight loss, inanition, angular stomatitis, anemia, lymphopenia, hypoproteinemia with hypoalbuminemia, and marked thymic involution. in addition, systemic invasion by gram-negative rods was documented. however, no edema was produced, and animals did not survive for longer than six weeks on the protein-deficient diet. one percent glycogen was found to b ... | 1978 | 98598 |
| antigenic relationships between the typhus and spotted fever groups of rickettsiae. | paired sera from cases of epidemic typhus in ethiopia and from probable cases of rocky mountain spotted fever (rmsf) in the united states were examined by microagglutination (ma) and microimmunofluorescence (micro-if) tests for antibodies against rickettsia prowazekii, rickettsia typhi, rickettsia canada, rickettsia rickettsii, rickettsia conorii and ricksettsia akari. igg and igm antibodies against the various rickettsiae were titrated with specific fluorescein-conjugated anti-igg and anti-igm ... | 1978 | 99029 |
| the effect of complement depletion on bacterial lipopolysaccharide (lps)-induced hemodynamic and hematologic changes in the rhesus monkey. | lipopolysaccharide (lps) isolated from salmonella minnesota r595 or from escherichia coli 0111:b4 induces hypotension in rhesus monkeys with normal complement levels. this hypotension is accompanied by decreased total peripheral resistance. the depletion of c3 and terminal complement components by prior intraperitoneal administration of the anticomplementary protein cobra factor did not alter the hemodynamic changes which occur following the rapid injection of 5 mg/kg of r595 lps, the infusion o ... | 1978 | 99042 |
| plaque formation by strains of spotted fever rickettsiae in monolayer cultures of various cell types. | some strains of spotted fever rickettsiae could be distinguished by their ability or inability to form plaques in monolayer cultures of various mammalian and avian cell types. | 1978 | 99454 |
| trifluridine in resistant human herpetic keratitis. | patients with active dendritic herpetic keratitis that was unresponsive to topical idoxuridine or vidarabine therapy were treated topically with a 1% solution of trifluridine. the dendritic ulcers healed in an average time of 6.1 days. all patients tolerated the drug well except for one patient in whom a reversible crystalline epithelial keratitis developed. | 1978 | 100084 |
| a kinetic study of ribulose bisphosphate carboxylase from the photosynthetic bacterium rhodospirillum rubrum. | the activation kinetics of purified rhodospirillum rubrum ribulose bisphosphate carboxylase were analysed. the equilibrium constant for activation by co(2) was 600 micron and that for activation by mg2+ was 90 micron, and the second-order activation constant for the reaction of co(2) with inactive enzyme (k+1) was 0.25 x 10(-3)min-1 . micron-1. the latter value was considerably lower than the k+1 for higher-plant enzyme (7 x 10(-3)-10 x 10(-3)min-1 . micron-1). 6-phosphogluconate had little effe ... | 1978 | 100101 |
| an apparent outbreak of rickettsial illness in costa rica, 1974. | a focal outbreak of highly fatal disease occurred in eastern costa rica in 1974. no rickettsial spotted fevers have previously been reported in costa rica. nevertheless, the available evidence points to an unidentified rickettsial pathogen, probably of the spotted fever group, as the agent responsible for this outbreak. | 1978 | 100162 |
| identification of rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence. | with slight modification of a trypsin digestion technique, rickettsia rickettsii were demonstrated specifically by immunofluorescence staining in formalin-fixed, paraffin-embedded tissue sections from a human, rhesus monkey, and guinea pig with rocky mountain spotted fever and in infected membranes from a chicken embryo. tissues were cut at 4 micron and, using geltain as a tissue adhesive, were hydrated in a routine manner. sections were then digested in refrigerated 0.1% trypsin for 16 h, washe ... | 1978 | 100509 |
| comparative ultrastructural study on the cell envelopes of rickettsia prowazekii, rickettsia rickettsii, and rickettsia tsutsugamushi. | rickettsia tsutsugamushi differs from other rickettsiae in its cell envelope organization. the differences were made evident through a comparative study of the outer envelope of r. tsutsugamushi, r. prowazekii, and r. rickettsii by electron microscopy. | 1978 | 101465 |
| serologic typing of rickettsiae of the spotted fever group by microimmunofluorescence. | 1978 | 101593 | |
| distribution and prevalence of spotted fever group rickettsiae in ticks from south carolina, with an epidemiological survey of persons bitten by infected ticks. | live ticks removed from human hosts were tested for the presence of spotted fever group rickettsiae from 1974 through 1976. spotted fever group rickettsiae were detected in dermacentor variabilis, amblyomma americanum, amblyomma maculatum, and ixodes scapularis. persons from whom positive ticks were removed in 1974 and 1975 were questioned about ensuing illness. eleven of 51 persons from whom rickettsia-positive d. variabilis were removed reported some unexplained combination of symptoms compati ... | 1978 | 103448 |
| growth characteristics of atypical mycobacteria in water and their comparative resistance to disinfectants. | with the increasing significance of group iv atypical mycobacteria as etiological agents in a variety of infections, studies were conducted to determine their growth capabilities in water and their comparative resistance to disinfectants used to decontaminate hospital equipment. isolates of mycobaterium chelonei (tm strains) from peritoneal fluids of patients and peritoneal dialysis machines were able to multiply in commercial distilled water, with generation times at 25 degrees c ranging from 8 ... | 1978 | 104656 |
| transfer of 2,4,5,2',4',5'-hexachlorobiphenyl and 2,2-bis-(p-chlorophenyl),1,1,1-trichloroethane (p,p'-ddt) from maternal to newborn and suckling rats. | pregnant rats were given a small dose of 14c-2,4,5,2',4',5'-hexachlorobiphenyl (hcb) and 3h-ddt intraperitoneally. the transfer of hcb and ddt through the placenta and milk was then investigated. transfer through the placenta was 2.7 and 1.5% (respectively) of the initial doses; transfer through milk was 39.2 and 21.5%. hcb is obviously more transferable than ddt through the placenta and milk, the ratio of the amount of hcb transferred through milk to the amount transferred through the placenta ... | 1978 | 104695 |
| external layers of rickettsia prowazekii and rickettsia rickettsii: occurrence of a slime layer. | using a simple specific-antibody stabilization procedure on organisms gently liberated from their host cells, we have demonstrated by electron microscopy that rickettsia prowazekii and rickettsia rickettsii possess a coat of variable thickness, external to the outer leaflet of the cell wall and the structure designated by others as a "microcapsule," which corresponds most closely to the slime layer of certain other bacteria. reactions in the methenamine silver and ruthenium red staining procedur ... | 1978 | 83297 |
| proteolytic enzymes of the k-1 strain of streptomyces griseus obtained from a commercial preparation (pronase). effect of ph, metal ions, and amino acids on aminopeptidase activity. | 1978 | 22544 | |
| ultrastructural localization of calcium around the membrane of the surface connected system in the human platelet. | the localization of calcium in the membrane system of human platelets was determined by ultrahistochemical methods equipped with an electron probe x-ray microanalyzer. after potassium oxalate-glutaraldehyde treatment large amounts of electron opaque precipitates were observed around the membrane of the surface connected system. electron probe x-ray microanalysis clearly defined that the precipitates were composed of calcium oxalate. the localization of calcium on the membrane of the surface conn ... | 1978 | 96043 |
| verification of human fetal breathing with phased array ultrasound imaging. | continuous observation of fetal movement patterns is a novel and useful capability of new high-speed ultrasound imaging systems. confirmatory documentation of human fetal breathing as a component of these movement patterns has been achieved using a phased-array real time ultrasound sector scanning system. this system permits direct visualization of fetal breathing movements. permanent recordings can be made on videotape. recordings can also be made as a time-motion echocardiograms during continu ... | 1978 | 96144 |
| laboratory diagnosis of rocky mountain spotted fever by immunofluorescent demonstration of rickettsia in cutaneous lesions. | direct immunofluorescent staining for rickettsia rickettsii was performed on cryostat sections of skin biopsies from 27 patients suspected of having rocky mountain spotted fever. in nine of the 17 patients whose final diagnosis was rocky mountain spotted fever, coccobacillary forms of r. rickettsii were identified in endothelium and vascular walls within the dermis. facotrs recognized as contributing to false-negative results were prior treatment with tetracycline or chloramphenicol for 24--48 h ... | 1978 | 96691 |
| regulation of the in vitro synthesis of the alpha-peptide of beta-galactosidase directed by a restriction fragment of the lactose operon. | 1978 | 96823 | |
| release of dopamine in the nucleus accumbens of rats by thyrotropin releasing hormone (trh) [proceedings]. | 1978 | 96901 | |
| effect of immunosuppression on rickettsia rickettsii infection in guinea pigs. | the role of the immune response in the pathogenesis of rickettsia rickettsii infection in guinea pigs was investigated by immunosuppression, using antilymphocyte serum. twenty guinea pigs were inoculated with r. rickettsii, sheila smith strain, on day 0. fifteen animals received antilymphocyte serum on days --1, 0, 2, 4, and 6. five animals received normal rabbit serum on the same schedule. at necropsy, specimens were collected for histological examination, rickettsial immunofluorescence, ricket ... | 1978 | 97223 |
| detection of the rocky mountain spotted fever agent, rickettsia rickettsii, in dead ticks, dermacentor andersoni. | rickettsia rickettsii remained viable and retained chromophilic properties for not more than 24 h after dermacentor andersoni were killed by freezing. antigenic reactivity was detected for at least 71 days by direct immunofluorescence. however, rickettsiae in ticks suffocated with mineral oil remained pathogenic for at least 14 days. accordingly, ticks removed from a host by mineral oil or dying from desiccation in transit are still suitable for rickettsial examination. | 1978 | 97233 |
| an improved electrophoretic method for identifying antibiotics with special reference to animal tissues and animal feeding stuffs. | 1978 | 97257 | |
| prophylactic treatment of rocky mountain spotted fever. | prophylactic treatment of rocky mountain spotted fever with a single dose of oxytetracycline was investigated in guinea pigs. disease was prevented when treatment was administered shortly before expected onset. relapses occurred when treatment preceded expected onset by 48 h or more. | 1978 | 97307 |
| rickettsiae: a new vaccine for rocky mountain spotted fever. | 1978 | 97783 | |
| effects of budr on developmental functions of dictyostelium discoideum. | the development of dictyostelium discoideum cells, as measured by spore yield, is somewhat more sensitive to the presence of budr during vegetative growth than is growth itself. observations on the development of control and budr-grown cells, their protein labelling patterns and assays of 4 developmentally regulated proteins all reveal a consistent picture. budr appears to block spore formation by partially inhibiting several or many different earlier events during development. the relative sens ... | 1978 | 207443 |
| a fair deal for the handicapped. | 1978 | 148882 | |
| [allergy and lectins: action between ige-mediated histamine release and glycoproteins from viscum album l. (mistletoe)]. | low-molecular constituents from viscum album (toxic) release, in irritatively toxic manner, histamine from human leukocytes without destroying the cells (cytotox test). this histamine release is prevented by preincubation with viscum lectins. the viscum lectin blocks the fc-portion of allergen-specific ige against anti-ige [125i]. lectin also inhibits the allergen-specific histamine release from human leukocytes occurring through ige; this can be demonstrated on leukocytes from patients with ato ... | 1978 | 88141 |
| systemic hyalinosis (juvenile hyaline fibromatosis). ultrastructure of the hyaline with particular reference to the cross-banded structure. | systematic hyalinosis (juvenile hyaline fibromatosis) is characterized by hyalinized skin lesions. electron microscopic examination of a hyalinized skin tumor from a 19-year-old man with this syndrome revealed that the hyaline was composed of ruthenium red-positive ultrastructures (granules, filaments, and a kind of cross-banded structure), indicating the presence of glycosamino-glycan or glycoprotein, and a small number of thin collagen fibrils. using a new ruthenium red staining method combine ... | 1979 | 88923 |
| inhibition of spontaneous transformation of rat embryo cells releasing endogenous type c virus by virus-specific antiserum. | noninbred sprague-dawley rat embryo cell clones predictably undergo transformation after 20-30 in vitro passages following spontaneous release of endogenous rat leukemia virus (ralv). in the presence of ralv-specific antiserum, virus production and infectivity were reduced and transformation was delayed from 6 to 25 weeks. transformation was not associated with an increased expression of kirsten murine sarcoma virus-related src gene rna. | 1979 | 89211 |
| in-phase brain activities during arousal and sleep. | eeg of sensorimotor area, emg of neck muscles and unit activity in lateral geniculate (lg) nucleus, recorded in freely moving cats, were analysed for the presence of correlations between them. the 3 activities were first integrated with a 2 sec time constant, then a correlation coefficient was assessed between time-linked points of the 3 records for periods of 40 sec. the average vlaues of the correlation coefficients were found to increase from arousal through slow synchronized sleep (s sleep), ... | 1979 | 89948 |
| prolonged survival of corneal allografts in rabbits treated with cyclosporin a. | 1979 | 90771 | |
| characterization of 40,000- and 25,000-dalton intermediate precursors to rauscher murine leukemia virus gag gene products. | under steady-state labeling conditions, rauscher murine leukemia virus-infected nih swiss mouse cells contain at least three major polyproteins derived from the viral gag gene. they have molecular weights of 65,000, 40,000, and 25,000. they have been termed ppr65gag, pr40gag, and ppr25gag. ppr65gag has been shown by a number of laboratories to be composed of all four core proteins (p15, pp12, p30, and p10). in this paper, pr40gag was found to contain p30 and p10 antigenic determinants and peptid ... | 1979 | 94357 |
| effect on rats and mice of a diet with low tryptophan content (maize flour). | female wistar rats when crowded together become aggressive if fed a diet with low tryptophan (trp) content (maize, flour, mf). when isolated during 30 days and fed mf they show a decrease of weight, of total plasma trp, and of trp and 5-hydroxytryptamine (5-ht) in brain stem, but 5-hydroxyindolacetic acid (5-hiaa) of the same cerebral area does not change. these results partially agree with other authors observations. mice isolated during 47 days and fed with mf do not show any significant weigh ... | 1979 | 95611 |
| [intravenous cholangiography in hyperbilirubinaemia (author's transl)]. | the effect of bilirubin on biliary and renal excretion of methylglucamine-iodipamide at an infusion rate of 1.3, 2.6 and 5.2 mu mol/min/kg was studied by intravenous injection into five dogs with normal liver functions and chronic duodenal fistulas. unconjugated bilirubin administered in a dose of 0.1 mu mol/min/kg reduced biliary iodipamide excretion and concentration significantly, but did not affect renal contrast material excretion. this indicates that the unsatisficatory radiological result ... | 1979 | 153309 |
| mg2+ and atp effects on k+ activation of the ca2+-transport atpase of cardiac sarcoplasmic reticulum. | atp and the divalent cations mg2+ and ca2+ regulated k+ stimulation of the ca2+-transport atpase of cardiac sarcoplasmic reticulum vesicles. millimolar concentrations of total atp increased the k+-stimulated atpase activity of the ca2+ pump by two mechanisms. first, atp chelated free mg2+ and, at low ionized mg2+ concentrations, k+ was shown to be a potent activator of atp hydrolysis. in the absence of k+ ionized mg2+ activated the enzyme half-maximally at approximately 1 mm, whereas in the pres ... | 1979 | 162038 |
| transformation by reticuloendotheliosis virus: development of a focus assay and isolation of a nontransforming virus. | 1979 | 219596 | |
| effect of quantity and quality of igg antibodies on blocking of allergenic histamine release in vitro. | in a study of the protective role of igg antibodies in allergen injection therapy, serum antibodies to timothy grass allergens were raised in rabbits and tested for inhibition of histamine release from basophils of grass pollen-sensitive human subjects. rabbit sera were not inhibitory until late in the immune response when large amounts of relatively low affinity igg antibodies were detected by primary binding. inhibition of histamine release by late sera required preincubation of allergen and a ... | 1979 | 84798 |
| expression in escherichia coli of chemically synthesized genes for human insulin. | synthetic genes for human insulin a and b chains were cloned separately in plasmid pbr322. the cloned synthetic genes were then fused to an escherichia coli beta-galactosidase gene to provide efficient transcription and translation and a stable precursor protein. the insulin peptides were cleaved from beta-galactosidase, detected by radioimmunoassay, and purified. complete purification of the a chain and partial purification of the b chain were achieved. these products were mixed, reduced, and r ... | 1979 | 85300 |
| specificity of human lymphocytes primed against allogeneic cells in vitro. ii. discrimination and cross-reactivity in repeated priming. | when studying the specificity of human lymphocytes primed in vitro against hla-d determinants on allogeneic cells, it was found that specific restimulation of the primed cells 10 days after the first priming did not influence their discriminatory power compared to cells primed only once. likewise, priming to one hla-d determinant and repeated priming against another hla-d determinant did not change the discrimination for the first priming antigen. neither was there any increased relative reactiv ... | 1979 | 87030 |
| cell types required for h-2-restricted cytotoxic responses generated by trinitrobenzene sulfonate-modified syngeneic cells or trinitrophenyl-conjugated proteins. | murine spleen cells were fractionated over nylon wool or sephadex g-10 columns, and the cell types involved in the generation of trinitrophenyl (tnp)-specific, h-2 restricted (tnp-self) cytotoxic effector cells were studied from cultures stimulated with trinitrobenzene sulfonate (tnbs)-modified syngeneic cells, tnp-conjugated soluble proteins such as bovine gamma-globulin (tnp-bgg), or bovine serum albumin (tnp-bsa). unfractionated or nylon nonadherent responding cells generated such effectors, ... | 1979 | 87418 |
| increased levels of dihydrofolate reductase in rifampin-resistant mutants of bacillus subtilis. | several independent, spontaneous rifampin-resistant mutants of bacillus subtilis were isolated and found to have an increased resistance to trimethoprim, an inhibitor of dihydrofolate reductase. this increased resistance in the rif mutants was the result of a specific threefold increase in the activity of dihydrofolate reductase, since six other enzymes examined remained unchanged. this increased level of dihydrofolate reductase and the trimethoprim resistance were cotransformed (100%) with the ... | 1979 | 106041 |
| biological properties of antibodies against rat adipocyte intrinsic membrane proteins. dependence on multivalency for insulin-like activity. | antisera from rabbits injected with rat adipocyte plasma membranes or intrinsic proteins from such membranes, obtained by a dimethylmaleic anhydride extraction step, mimicked the action of insulin on both glucose transport and lipolysis in intact adipocytes. biological activity in both types of antisera was mediated by immunoglobulin binding to one or more intrinsic proteins of the adipocyte plasma membrane since fat cells were unresponsive to all antisera absorbed with dimethylmaleic anhydride- ... | 1979 | 107169 |
| discrepancies in weil-felix and microimmunofluorescence test results for rocky mountain spotted fever. | only 4.2% of 284 single specimens and 17.6% of 51 pairs of sera reactive in weil-felix agglutination tests for rocky mountain spotted fever were confirmed by a specific rickettsia rickettsii microimmunofluorescence test. | 1979 | 107194 |
| sarcocystinae: nomina dubia and available names. | examination of the original descriptions of the species of sarcocystis in cattle, sheep, and swine, and of isosporid oocysts shed sporulated by dogs, cats, man, and other carnivores, has shown that it is not possible in most instances to identify unambiguously recently recognized taxa. the original descriptions are insufficient, and because no type specimens exist, could apply to two or more of the presently recognized taxa. we consider the following nomina dubia: sarcocystis hirsuta s. miescher ... | 1979 | 107666 |
| ascending aorta-supraceliac abdominal aorta bypass: successful removal of an infected graft in the descending thoracic aorta. | an infected graft and a mycotic pseudoaneurysm were successfully resected by employing an ascending aortasupraceliac abdominal aorta bypass graft in a 19-year-old man. he had formerly undergone graft replacement surgery for traumatic aneurysm of the descending thoracic aorta, with the aid of a temporary external bypass graft. after this first operation, the patient had suffered from septicemia due to psudomonas aeruginosa, which resulted in formation of mycotic pseudoaneurysms at the distal anas ... | 1979 | 108052 |
| [reevaluation of the effect of certain parameters on the survival of neisseria gonorrhoeae]. | lysis and survival of 4 gonococcal strains were studied under different conditions in the presence of divalent cations and glycerol. the stability and the viability of the gonococcal cells were not enhanced by any of these compounds. | 1979 | 108131 |
| antibody to b. subtilis dna polymerase iii: use in enzyme purification and examination of homology among replication-specific dna polymerases. | bacillus subtilis dna polymerase iii (pol iii), an arylhydrazinopyrimidine-sensitive, replication-specific enzyme, was used to generate a non-precipitating rabbit antibody which specifically inhibited pol iii activity in vitro. the antibody was used to examine structural relationships among several dna polymerases, and it was linked covalently to agarose; the antibody:agarose was employed to develop a rapid, selective method of purification of catalytically active b. subtilis pol iii. | 1979 | 108667 |
| rocky mountain spotted fever in connecticut: human cases, spotted-fever group rickettsiae in ticks, and antibodies in mammals. | three parameters were used in 1976 and 1977 to assess the status of rocky mountain spotted fever (rmsf) in connecticut--compilation and review of clinical data on suspected human cases for the 13-year period 1965--1977, examination of tick tissues for spotted fever-group rickettsiae by the hemolymph test and direct immunofluorescence, and analyses of mammalian sera for antibodies against rickettsia rickettsii. there were six presumptive rmsf cases which probably originated in connecticut. four o ... | 1979 | 111543 |
| diagnosis of rocky mountain spotted fever by immunofluorescent identification of rickettsia rickettsii in skin biopsy tissue. | 1979 | 113518 | |
| exposure of guinea pigs to rickettsia rickettsii by aerosol, nasal, conjunctival, gastric, and subcutaneous routes and protection afforded by an experimental vaccine. | guinea pigs were inoculated with rocky mountain spotted fever by the aerosol, conjunctival, subcutaneous, intragastric, and intranasal routes. rickettsial infection was produced by all routes except intragastric. all animals with clinical signs of disease developed agglutinating antibody, and most developed a cell-mediated immune response. disease produced by all experimental routes (except intragastric) was indistinguishable. the tissue culture-derived inactivated vaccine produced in this labor ... | 1979 | 114488 |
| natural infection of dogs on cape cod with rickettsia rickettsii. | four isolates of rickettsiae from sick dogs on cape cod, mass., were serologically identical to isolates of rickettsia rickettsii from human patients with rocky mountain spotted fever. the antigenic analysis used the indirect fluorescent-antibody test and antisera prepared in mice to each of the isolates and to reference strains of r. rickettsii and rickettsia montana. serological responses of infected dogs were specific for r. rickettsii, although antibodies to r. montana were also detected in ... | 1979 | 114534 |
| sugar hydrolases and their arrangement on the rat intestinal microvillus membrane. | the arrangement of the sugar hydrolases, sucrase-isomaltase, maltase, and lactase on the microvillus membrane of rat intestine was investigated by immunological technique. the enzymes were purified essentially free of each other to near homogeneity and antisera of high specificity were obtained against each. microvillus membranes were prepared routinely in high purity from rat intestine and contained an average 61% protein, 20% lipid, and 19% carbohydrate, with the sugar hydrolases comprising an ... | 1979 | 116006 |
| indirect hemagglutination test for detection of antibody to rickettsia rickettsii in sera from humans and common laboratory animals. | antibody production in humans and three species of laboratory animals infected with rickettsia rickettsii was determined with the indirect hemagglutination test. rabbits, guinea pigs, and mice were inoculated with r. rickettsii and bled at intervals. antibody which agglutinated both fresh and glutaraldehyde-fixed sheep erythrocytes sensitized with antigen prepared either from purified rickettsiae or from infected yolk sacs was found in rabbit sera at all intervals tested (10 to 59 days postinfec ... | 1979 | 120875 |
| evaluation of a killed rocky mountain spotted fever vaccine in cynomolgus monkeys. | a nonhuman primate model of rocky mountain spotted fever infection was developed in cynomolgus monkeys (macaca fascicularis) infected by the subcutaneous route or by aerosol. clinical responses, hematology and serum chemistry values, and pathological findings were similar to those found in humans ill with rocky mountain spotted fever. the clinical model was then used to test the efficacy of a killed rocky mountain spotted fever vaccine grown in chicken embryo cells. monkeys were immunized with v ... | 1979 | 120877 |
| in vitro studies of rickettsia-host cell interactions: ultrastructural changes induced by rickettsia rickettsii infection of chicken embryo fibroblasts. | secondary chicken embryo fibroblasts infected with the sheila smith strain of rickettsia rickettsii and grown in monolayer culture undergo rapid morphological alterations. transmission electron microscopic examination of cells at intervals after infection showed several progressive host cell lesions, including widespread dilatation of the rough endoplasmic reticulum and outer nuclear envelope and the accumulation of electron-dense material within the cisternae of intracellular membranes. dilatat ... | 1979 | 121115 |
| [1st case of rocky mountain fever in costa rica. central america]. | 1979 | 121621 | |
| alteration in local and systemic immune capacity after exposure to bursts of co. | 1979 | 387409 | |
| influence of the substituent radicals in antimonyl naphthalein derivatives on the potentialities of anti-schistosomal activity in mice. | 1979 | 262474 | |
| cytostatic activity of peripheral blood monocytes against bronchogenic carcinoma cells in patients with lung cancer. | cytostatic acitivity of peripheral blood monocytes against cultured cell lines of bronchogenic carcinoma was examined in patients with lung cancer. cytostatic activity in lung cancer patients with neither augmented nor suppressed as compared with that of controls such as normal healthy persons, patients with malignancies other than lung cancer, and patients with benign respiratory diseases. there was no correlation between the cytostatic activity of monocytes and the advance of clinical stages o ... | 1979 | 229054 |
| distribution of binding sites for 125i-labeled alpha-bungarotoxin in normal and deafferented antennal lobes of manduca sexta. | 125i-labeled alpha-bungarotoxin has been used to determine the distribution of putative acetylcholine receptors in normal and chronically deafferented antennal lobes in the brain of the moth manduca sexta. toxin-binding sites are confined to synaptic regions in deafferented lobes. these findings suggest that receptors can develop in the insect central nervous system independently of normal synaptic influences. | 1979 | 284367 |
| synthesis of plasma membrane proteins during development of dictyostelium discoideum. | 1979 | 421897 | |
| acute renal failure in rocky mountain spotted fever. | review of clinical and pathologic data from ten fatal cases of rocky mountain spotted fever (rmsf) revealed the importance of acute renal failure in the clinical course and of multifocal perivascular interstitial nephritis as the principal pathologic lesion. in nine cases, rickettsia rickettsii were demonstrated by immunofluorescence in the areas of vasculitis. evidence was lacking for the role of disseminated intravascular coagulation, glomerulonephritis, or myoglobinuria in the pathogenesis of ... | 1979 | 434998 |
| the efficacy of a potassium-rich diet compared to diuretic treatment on the renal elimination of thallium in the rat. | 1979 | 454183 | |
| comparison of individual and cumulative dose-response curves [proceedings]. | 1979 | 497601 | |
| kidney lesions in rocky mountain spotted fever: a light-, immunofluorescence-, and electron-microscopic study. | the essential pathologic lesion in rocky mountain spotted fever (rmsf) is a vasculitis that may involve the kidneys as well as the heart, brain, skin, and subcutaneous tissues. histopathologic information concerning the response of the kidneys in rmsf is rather limited, however. in this study renal tissue from 17 children who died of rmsf was examined by light, electron, and immunofluorescence microscopy. a lymphocytic or mixed inflammation, or both, involving vessels and interstitium of the kid ... | 1979 | 525676 |
| incomplete dosage compensation in an evolving drosophila sex chromosome. | cellular autoradiography was used to measure relative rates of chromosomal rna synthesis and to examine the regulatory phenomenon of x-linked dosage compensation in drosophila miranda, a species containing two distinct, nonhomologous x chromosomes (x1 and x2). the x1 chromosome was found to be dosage-compensated, since the rate of rna synthesis along the single x1 chromosome in males equaled that of both x1 chromosomes in females. unlike other sex chromosomes that have been studied, the more rec ... | 1979 | 273254 |
| drug-nucleic acid interactions: conformational flexibility at the intercalation site. | the conformational features of the intercalation site in polynucleotides were examined. we found that, for all the crystal structures of drug-dinucleoside complexes studied thus far, two torsion angles differ from those found in a rna (phi and chi) and that alternate sugar puckering is not a prerequisite for intercalation. this intercalation geometry, which is the basis of helix axis displacement in a polymer, would necessitate conformational changes in the adjacent nucleotides. the base-turn an ... | 1979 | 273246 |
| international study for health professionals. | 1979 | 273161 | |
| humour as a "courage mechanism". | 1979 | 273012 | |
| radiographic artifact. | 1980 | 273544 | |
| [alterations of plasma plasminogen and fibrinogen, serum fibrin degradation products and degree of adp induced platelet aggregation in acute myocardial infarction (author's transl)]. | 1980 | 550980 |