Publications

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production of neuraminidase by l forms of vibrio cholerae. 196114468120
a highly selective gelatin-taurocholate-tellurite medium for the isolation of vibrio cholerae. 196114475439
cholera bacteriophages in preventing gut inflammatory action of vibrio cholerae. 196114477034
purification and properties of neuraminidase from vibrio cholerae. 196113681288
[morphological modifications of vibrio cholerae after autolysis in a glucose medium]. 196113896481
[a medical study of the low saturated fatty acid. 3. effect of low saturated fatty acids on vibrio comma]. 196114495676
evaluation of tests for differentiating vibrio cholerae and e1 tor vibrios. 196113773642
interactions of vibrio cholerae, shigella flexneri, enterococci, and lactobacilli in continuously fed cultures. 196113739505
action of polymyxin b on vibrio cholerae. 196113903784
anaerobic dissimilation of glucose by vibrio comma. 196113923820
studies with vibrio cholerae in the ligated loop of the rabbit intestine. 196113894076
studies on antigens of vibrio cholerae by gel diffusion technique. iii. antigenic make-up of phage types. 196113704959
studies on antigens of vibrio cholerae by gel diffusion technique. iv. antigenic relationship between non-agglutinating and agglutinating vibrios. 196113704960
screening of some antibiotics of vibrio cholerae. 196113710687
[nucleic acids in vibrio cholerae and paracholera]. 196213972595
action of lysozyme on vibrio cholerae. 196213952057
[on differential plating media for isolation of vibrio cholerae. 3. on an enriched medium for vibrio cholerae]. 196214013521
attempts to freeze some bacteriophages to ultralow temperatures.a variety of bacteriophages specific for different hosts, including bacillus cereus, escherichia coli, pseudomonas aeruginosa, serratia marcescens, shigella dysenteriae, staphylococcus aureus, and vibrio comma, were frozen at a controlled rate to liquid nitrogen temperatures, and then quick-thawed. glycerol (10%) was used as a protective additive. quantitative determinations showed from 10% to virtually 100% recovery in the various cases. host specificity, plaque morphology, and, in one case, ra ...196214021543
effect of ultraviolet radiation on the incorporation of radioactive phosphorus in growing and non-growing cells of vibrio cholerae. 196214042088
studies on the action of some antibiotics on vibrio cholerae. i. action of penicillin. 196213903782
action of some antibiotics on vibrio cholerae. ii. action of chloramphenicol on the free amino-acid pool. 196213903783
[a possibility for the utilization of fluorescent antibodies in rapid detection of vibrio cholerae in water]. 196213878926
characterization of cholera typing phages. iv. phage-resistant mutants of vibrio cholerae. 196214477037
[research with a view to establishment of a lysotype for vibrio cholerae and vibrio el tor]. 196214479579
[some data on the phagolysis of vibrio cholerae in water]. 196214479856
[contribution to the study of o antigen complex of vibrio. ii. spontaneous selective liberation of the vibrio cholerae and v. e1 tor cell wall with loss of o agglutinability. isolation of the specific agglutinogen]. 196213896482
laboratory studies on the el tor vibrio.the identity of the el tor vibrio is a controversial question that the usual methods of bacteriological investigation have as yet failed to settle. in this paper, the author presents the results of a study of the interrelationships between el tor vibrios, true cholera vibrios and water vibrios, as revealed by the behaviour of the vibrios in the bile system and in the small intestine of experimental animals.the vibrios investigated included two strains isolated at the el tor quarantine station on ...196313986981
[effect of potassium periodate and vibrio cholerae filtrate on antibody formation in the blood serum]. 196314097603
preliminary studies on the development of a live oral vaccine for anti-cholera immunization.since humoral anti-o antibodies play little part in protective immunity against cholera, and the infecting organisms remain limited in the gut, effective prophylaxis will require the production of active immunity in cells of the mucous membrane of the intestinal canal. it has not been possible to achieve this objective satisfactorily by injections of killed cholera cultures. in laboratory studies for a solution of the problem it has been shown that vibrio cholerae and v. el tor strains possess i ...196314107748
formation and motility of spheroplasts of vibrio cholerae induced by penicillin, glycine and lithium chloride. 196314101011
vibrio cholerae and colicines. 196314109983
studies on typing of cholera vibrios by bacteriophage. v. geographical distribution of phage-types of vibrio cholerae. 196314154194
[phenomena of microbial variation with observations on "vibrio comma pottevin"]. 196314166965
[study of vibrio cholerae using the electron microscope and the relation between the morphological aspect and o agglutination]. 196314107749
preparation of spheroplasts from vibrio comma.chatterjee, b. r. (baylor university college of medicine, houston, texas), and robert p. williams. preparation of spheroplasts from vibrio comma. j. bacteriol. 85:838-841. 1963.-spheroplasts were prepared from several strains of vibrio comma by lysozyme treatment combined with freezing and thawing of the organisms. the optimal concentration of lysozyme was 50 mug/ml, although some spheroplasts formed at a concentration of 10 mug/ml. higher concentrations (200 mug/ml) caused lysis of cells along ...196314044952
sialidase (neuraminidase) of corynebacterium diphtheriae.warren, leonard (national institute of arthritis and metabolic diseases, bethesda, md.) and c. w. spearing. sialidase (neuraminidase) of corynebacterium diphtheriae. j. bacteriol. 86:950-955. 1963.-the characteristics of a sialidase produced by corynebacterium diphtheriae were studied. the enzyme was partially purified from preparations of diphtheria toxin on a column of sephadex g-75. by this means the lethal factor of diphtheria toxin was separated, in part, from the sialidase activity. there ...196314080806
transmission of multiple drug-resistance from shigella flexneri to vibrio comma through conjugation. 196314095980
some observations on the agglutination reaction of vibrio cholerae. 196314034946
a new method for the differentiation of vibrio comma and vibrio el tor. 196313952447
protoplast formation as the mechanism for immune lysis of vibrio cholerae. 196313959442
studies on the haemolytic activity of el tor vibrios.in view of reports of inconsistent results with the haemolytic test for identification of the el tor biotype of vibrio cholerae, a study was made of the experimental variables involved in order to achieve more precise standardization of the procedure. it was found that different types of media and different incubation times of a culture in a particular medium exerted a profound influence on the results. the authors describe the materials and conditions for performance of a reliable haemolytic te ...196313944689
[the thermostable antigens of vibrio cholera. localization and isolation of the specific o agglutinogen]. 196313946268
vibrio cholerae infection in the embryonated egg. 196313946546
experimental cholera produced by toxin prepared by ultrasonic disintegration of vibrio comma. 196316561998
the effect of gastrointestinal enzymes on cholera toxin.in clinical cases of cholera vibrio cholerae grows, multiplies and undergoes lysis in the intestine. although there are numerous works on the enzymatic make-up of v. cholerae, there is hardly any literature on the effect of different gastrointestinal enzymes on the toxin in bringing about the signs and symptoms of the disease. according to one school of thought, cholera toxin plays an important role in the pathogenesis of the disease.the effects of gastrointestinal enzymatic extracts of rabbit a ...196320604142
the bacteriophage-susceptibility test in differentiating vibrio cholerae and vibrio el tor.the haemolytic properties of el tor vibrios are usually utilized to differentiate them from the non-haemolytic cholera vibrios. in some freshly isolated vibrio el tor strains, however, the haemolytic property may be ill-developed and this test may then fail to reveal the true identity of the strains. in order to overcome this difficulty a number of tests have been developed. investigations reported in this paper indicate that, of these, the bacteriophage-susceptibility test gives the most persis ...196320604144
bacteriophage typing of cholera.a bacteriophage-typing scheme for vibrio cholerae has been developed on the basis of the pattern of susceptibility of v. cholerae strains to four groups of freshly isolated cholera bacteriophages. some 4066 strains of v. cholerae isolated in calcutta during the period 1955-61 have been classified into seven types and subtypes. less than 1% of the strains were untypable. no correlation was found to exist between the phage-types and serological types of v. cholerae. in lysogenic strains, however, ...196320604145
an experimental study on the usefulness of bacteriophage in the prophylaxis and treatment of cholera.five different samples of bacteriophages were tried on weanling rabbits intra-intestinally infected with the inaba 569 b strain of vibrio cholerae. three of these prevented the onset of the disease and proved useful in the treatment of early cases of experimental cholera. the prophylactic and curative (if administered early) values of choleraphage observed during these studies appear to agree with the observations of several workers in clinical cases. one of the choleraphages used proved to be v ...196320604146
[dental radiographic diagnosis in a public health dentistry district. a follow-up study]. 1963278234
leptomeningeal plasmacytosis. case report and considerations on treatment.we describe a 68-year-old patient with a plasma cell leukaemia in haematological remission presenting with massive intracranial leptomeningeal plasmocytic infiltration (lpi) and hydrocephalus. he was treated with skull irradiation and a combination of intraventricular and lumbar intrathecal therapy with methotrexate. neurologic improvement and clearance of plasma cells from the cerebrospinal fluid was reached after 2 weeks of treatment but prolonged follow-up was interrupted by a lethal gastro-i ...19632555099
cerebral toxoplasmosis in the acquired immune deficiency syndrome.we examined the clinical and pathological features of 26 patients who presented with a diagnosis of cns toxoplasmosis. patient data was analyzed with respect to demographics, clinical presentation, treatment course and pathology. patients presented with a wide variety of signs and symptoms. all patients had positive serum antitoxoplasma igg; ring enhancing lesion(s) were present on all but one brain ct scans. a series of guidelines in the management of cns toxoplasmosis in aids patients are pres ...19632555089
alveolar cell carcinoma complicating sickle cell anemia: a chance occurrence?alveolar cell carcinoma, a neoplasm associated with pre-existing inflammatory lung disease, has not been reported previously in patients with sickle cell disease. we present such a patient and suggest that chronic pulmonary scarring in this setting predisposed to development of his malignancy. as survival increases in individuals with sickle cell disease, alveolar cell carcinoma must be considered in these differential diagnosis of otherwise unexplained chronic pulmonary infiltrates.19632554726
dietary intake and colon cancer: sex- and anatomic site-specific associations.a case-control study was conducted in utah between july 1979 and june 1983 in which 231 cases of colon cancer identified through the utah cancer registry and 391 controls identified through random digit dialing were interviewed. odds ratios (or) were calculated comparing the highest exposure categories with the lowest exposure categories. the highest quintile of body mass index (weight (kg)/height (m)2 for males; weight (kg)/height (m)1.5 for females) was associated with increased risk in both m ...19632554725
a dynamic analysis of arterial blood pressure control systems. 19644157675
observations on the vitamin b12 content of propionibacterium freundenreichii & its possible utilization. 19644243509
enzyme activity of soluble cytoplasmic fraction of vibrio cholerae with special reference to aldolase, isocitrate, glucose-6-phosphate & malic dehydrogenases. 19644243510
enzyme induction in vibrio cholerae. 19644243511
treatment and prevention of rheumatic fever and rheumatic heart disease. 19644299209
treatment and prevention of rheumatic fever and rheumatic heart disease. 19644299209
[place of the sympathetic and parasympathetic nervous systems in the origin of renal vasoconstriction induced by bloodletting]. 19644960993
[place of the sympathetic and parasympathetic nervous systems in the origin of renal vasoconstriction induced by bloodletting]. 19644960993
[establishment of immunohistochemical technique for polyamine and its application in research of lung cancer].antiputrescine, antispermidine and antispermine were used to detect polyamine in normal and cancer tissues of lung by pap method. sections of lung cancer, which were known to have high concentration of polyamine, were used as positive control. results showed highly significant difference in the staining between the experimental and control groups. immunohistochemical assay further demonstrated that polyamine located mainly in the nucleus, nucleolus and cytoplasm of the cancer cells and was evenl ...19642555074
manner of attachment of flagella in vibrio comma. 196414203372
rapid identification of vibrio cholerae by darkfield microscopy.this article describes a rapid, simple and reproducible method for detecting vibrio cholerae in diarrhoeal patients. the method involves darkfield examination of a liquid stool specimen or a rectal swab immersed in broth and immobilization of v. cholerae by the addition of specific vibrio antisera. the authors state that in 80% of cases a definitive diagnosis is available within five minutes. there is no need for elaborate equipment or long training of technicians and the method is easily perfor ...196414215188
[studies on the colony mutation of vibrio comma and el tor vibrio on differential plating media containing bile salts]. 196414172295
[study of cholera antigen. iv. effect of the initial culture of vibrio cholerae on the quantity and specific activity of antigen complexes]. 196414182375
phage-host relationships in vibrio cholerae. 196414183393
new transport medium for shipment of clinical specimens. i. fecal specimens.cary, sylvia g. (walter reed army institute of research, washington, d.c.), and eugene b blair. new transport medium for shipment of clinical specimens. i. fecal specimens. j. bacteriol. 88:96-98. 1964.-a new transport medium for the collection and shipment of clinical specimens is described. preliminary studies indicate that, with initial fecal specimens, salmonella and shigella can be recovered for as long as 49 days, vibrio comma for 22 days, and pasteurella pestis for at least 75 days.196414197911
vibrio cholerae "malacca". 196414125192
electron microscopy of structure of flagellum of vibrio comma. 196414125373
[sensitivity of e1 tor vibrio cholerae to antibiotics]. 196414134700
agglutinating, lethal toxin and e1 tor haemolysin neutralizing potency of sera in cholera.there is a lack of agreement as to the significance of agglutination test results in cholera, and recent epidemics of "classic" vibrio comma and el tor infections have provided an opportunity to compare this test with two other serological procedures recently introduced in cholera work. these are determination of the circulating antitoxin expressed as the lethal toxin neutralizing power of a serum, and determination of the haemolysin neutralizing power through serial test-tube dilutions.applying ...196414215189
segregation of genetic factors during recombination in vibrio cholerae, strain 162.in this paper an analysis of genetic recombinants derived from crosses between two mutant stocks of vibrio cholerae, strain 162, differing from one another in nutritional requirements and other characters, is presented. it is shown that parent strains possessing a fertility factor (designated as the p factor) function as gene-donors while p(-) strains (without the p factor) serve as gene-recipients. linkage between two genetic factors (purine and valine + isoleucine) is demonstrated and the prob ...196414215190
hemagglutinating activity of vibrio comma. 196414232459
a comparison of virulence of vibrio cholerae strains for the embryonated egg. 196414233131
intracellular peptidases of vibrio cholera and their possible role in pathogenicity. 196414246491
enzymes in vibrio cholerae. 196414246492
immunochemistry of antigens of vibrio cholerae. 196414246494
neuraminidases and influenza virus infection in embryonated eggs.highly purified neuraminidase from influenza virus prevents embryonated eggs from infection by lee-b influenza virus. the degree of prevention afforded is equal to that of neuraminidases from vibrio cholerae and from clostridium perfringens when assayed at the same enzyme activity. the preventive effect is much lower against pr-8 virus. the results support the concept that the intact "receptor" containing sialic acid is required for the binding and infection of cells by influenza viruses.196414107434
[chemical composition of lipids and fatty acids in vibrio cholerae]. 196414207625
[quantitative composition of vibrio cholerae according to specific agar precipitation reaction]. 196414333946
[bacteriologic observations on the vibrio cholerae (el tor) isolated in cambodia]. 196414281486
[occurrence of yeast-like fungi of the genus candida and bacterial flora in the sputum of patients with different respiratory organ diseases]. 19654956310
response of the cardiovascular system of monkeys to stress. 19654957304
[beta-carotene transformed into vitamin a by a culture of pseudomonas aeruginosa]. 19654959479
characteristics of evoked potentials with short latent period in the parietal association cortex of the cat. 19654957780
characteristics of non-cholera vibrios isolated from cases of human diarrhoea.eighty-two organisms tentatively identified as non-cholera vibrios were isolated from cases of diarrhoea occurring in east pakistan. in 19 well-studied cases they were the predominant organism recovered, and a rise in agglutinating-antibody titre was found in six of these cases.because of this additional evidence that non-cholera vibrios cause diarrhoeal disease, it was necessary to evaluate simple screening tests as a means of recognizing them. it was found that all organisms that produced a ge ...19655294177
the root of flagella of vibrio cholerae. 19655294325
vibriocine production in the cholera and el tor vibrios.various tests have been developed to differentiate vibrio cholerae and v. el tor, since the latter was formerly considered to be of little clinical importance. more recently, however, it has become evident that these two organisms can produce an identical disease. consequently, it is of interest to detect similarities between them. in the present report, a method for the detection of bacteriocine ("vibriocine") activity of v. cholerae and v. el tor is described. the production of vibriocine appe ...19655322753
clinical and physiological observations during an epidemic outbreak of non-vibrio cholera-like disease in calcutta.during march through june 1964, an epidemic of acute non-vibrio diarrhoeal disease, closely simulating cholera, occurred in calcutta. to clarify the etiology and pathophysiology and improve the therapy of this illness, bacteriological and metabolic studies were performed on 145 consecutive hypotensive adult male patients admitted with acute diarrhoeal disease to the calcutta infectious disease hospital. bacteriological and serological studies clearly demonstrated that the majority of patients wi ...19655295147
a controlled field trial of the effectiveness of cholera and cholera el tor vaccines in the philippines. preliminary report; philippines cholera committee.in a controlled field trial on some 584 000 people in an endemic cholera el tor area in the philippines, it was demonstrated that cholera vaccines gave moderate protection of short duration. injection of a single dose of vaccine prepared from either vibrio cholerae or vibrio el tor gave over 50% protection for the first two months. the immunity conferred by the v. cholerae vaccine rapidly declined after three to four months. the v. el tor vaccine gave protection for six months, but its effective ...19655294176
protective antigens from el tor vibrios. 1. the preparation and properties of a purified protective antigen from an el tor vibrio (ogawa subtype).a biochemically and immunologically homogeneous antigenic fraction having the properties of a lipopolysaccharide has been isolated from the culture supernatant of an el tor vibrio (ogawa subtype). this antigen was very specifically protective for mice challenged with ogawa strains of either el tor vibrios or vibrio cholerae. rabbit antisera prepared against the antigen were passively protective for mice and highly vibriocidal but had little agglutinating activity. however, the antigen was able s ...19655294306
notes on food, beverages and fomites contaminated with vibrio cholerae. 19655295150
some observations on vibrio cholerae strains isolated during the controlled field trial of cholera vaccines in calcutta in 1964. 19655827507
[a method for the determination and study of polysaccharides in vibrio cholerae]. 19655885701
tetracycline sensitivity of vibrio cholerae in calcutta. 19655827191
studies on the growth inhibitory effect of erythrose on vibrio cholerae. 19655840410
effect of tetracycline in hypotensive patients with non-vibrio cholera-like disease in calcutta. 19655882326
on the therapeutic effect of gamma-inhibitor in mice infected with an inhibitor-sensitive, unadapted a2 influenza virus. 19654379537
[action of central nervous system inhibitory or stimulating drugs on the nicotinamide-adenine dinucleotides in the rat liver]. 19654379102
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