Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| sensitivity of branhamella catarrhalis to oral antibiotics. | b. catarrhalis is a potential pathogen in the upper and lower respiratory tract which has been implicated as a clinically important cause of chronic bronchitis and otitis media in children. since the late 1970s the proportion of b. catarrhalis strains elaborating beta-lactamase seems to have significantly increased; some centres are now reporting prevalence rates as high as 76%. such a dramatic increase in the number of beta-lactamase positive strains is of clinical importance when assessing the ... | 1986 | 3488193 |
| analysis of the relationship between ampicillin resistance and beta-lactamase production in branhamella catarrhalis. | 23 strains of branhamella catarrhalis, mainly isolated from patients with acute exacerbations of chronic bronchitis, were studied. the strains were selected on the basis of a positive beta-lactamase reaction using the cefinase disc or the nitrocefin method. no bands were visible by isoelectric focusing of the crude enzyme extracts of strains showing a weak positive reaction with the cefinase method. in the 15 remaining strains, at least 6 different isoelectric focusing patterns could be detected ... | 1986 | 3488194 |
| epidemiological and bacteriological findings on branhamella catarrhalis respiratory infections in the netherlands. | the frequency of isolation of branhamella catarrhalis from sputum in a laboratory in the southern part of the netherlands is reviewed; at present 23% of positive cultures contain these organisms. seasonal variations include a considerable reduction in frequency of isolation in the summer months. the possible role of heavy industry and air pollution is briefly discussed. evidence for the direct pathogenicity of b. catarrhalis is presented, and although this may be considered as only circumstantia ... | 1986 | 3488195 |
| classification of beta-lactamases from branhamella catarrhalis in relation to penicillinases produced by other bacterial species. | branhamella catarrhalis strains resistant to commonly used penicillins, and presently isolated, produce a beta-lactamase. most of these enzymes are chromosomally mediated, but a plasmid-mediated beta-lactamase has been described (enzyme bro-1). with reference to isoelectric points, 7 different enzymes have been identified: 6 chromosomally mediated and 1 plasmid-mediated. nevertheless, they have many common properties, such as being biosynthesised constitutively but with a low level of production ... | 1986 | 3488196 |
| isoelectric focusing of beta-lactamases from sputum and middle ear isolates of branhamella catarrhalis recovered in the united states. | branhamella catarrhalis obtained from the sputum of 146 patients with lower respiratory tract disease and from middle ear fluids of 26 children with otitis media were evaluated for beta-lactamase activity and the enzymes were characterised by isoelectric focusing (ief). 71% (103 of 146) of the sputum isolates and 77% (20 of 26) of the ear isolates produced beta-lactamase. by ief, the beta-lactamases of 113 of 123 (92%) strains revealed patterns identical with the ravasio type strain, having uniq ... | 1986 | 3488197 |
| plasmid-mediated beta-lactamase in branhamella catarrhalis. | the plasmid-mediated beta-lactamase in branhamella catarrhalis (bro-1), also occurring in moraxella nonliquefaciens, differs from other known plasmid-mediated beta-lactamases in gram-negative bacteria regarding substrate profile and isoelectric point. b. catarrhalis strains previously reported to produce beta-lactamases deviating from bro-1 were tested, and the beta-lactamases did not differ significantly from bro-1 in substrate profile, isoelectric point or relative substrate affinity index (rs ... | 1986 | 3488198 |
| inhibition of the beta-lactamases of branhamella catarrhalis by clavulanic acid and other inhibitors. | the beta-lactamases of branhamella catarrhalis ravasio and strain 1908 were readily inhibited by low concentrations of sulbactam, beta-halopenicillanic acids, mm 13902 and clavulanic acid. more detailed studies on the interaction of the ravasio beta-lactamase with clavulanic acid demonstrated that the enzyme had high affinity for the inhibitor (ki = 0.07 mumol/l) and was rapidly inhibited (t1/2 = 21 sec, kinhib. = 0.033/sec). two types of enzyme-inhibitor complex were formed, a transiently stabl ... | 1986 | 3488199 |
| inhibition of beta-lactamases in branhamella catarrhalis. | 1986 | 3488200 | |
| clinical and bacteriological evaluation of branhamella catarrhalis in respiratory infections. | the clinical significance of branhamella catarrhalis in respiratory infections is evaluated. 175 strains were isolated, mainly from the sputum, in 71 patients with respiratory infections. b. catarrhalis was most frequently isolated in mixed infections with haemophilus influenzae (38.3%), h. influenzae plus streptococcus pneumoniae (10.3%) or s. pneumoniae (9.7%). the rate of isolation of b. catarrhalis alone was as low as 5.1% and from mixed infections with pseudomonas aeruginosa, escherichia co ... | 1986 | 3488201 |
| direct and indirect pathogenicity of branhamella catarrhalis. | branhamella catarrhalis has been recovered from various sites of infection in the respiratory tract. these include chronic otitis media, tonsillitis, adenoiditis and pneumonia. this organism was recovered in many of these infections mixed with other aerobic, facultative anaerobic and anaerobic bacteria. increasing numbers of isolates of this organism have been noted to produce beta-lactamase. this may contribute to the high failure rate of penicillins in eradicating polymicrobial respiratory inf ... | 1986 | 3488202 |
| in honor of dr. sarah branham, a star is born. the realization of branhamella catarrhalis as a respiratory pathogen. | 1986 | 3488878 | |
| growth-enhancing effect of branhamella catarrhalis culture filtrates on the l-forms of haemophilus influenzae. | haemophilus influenzae is a common respiratory pathogen and recurrent infection due to h. influenzae is a phenomenon often present in patients with chronic respiratory tract infections. the effects of neisseria perflava and b. catarrhalis culture filtrates on the growth and reversion of h. influenzae l-forms were determined using the l-forms of h. influenzae induced and subcultured in a medium containing 10% sucrose and these culture filtrates. when each culture filtrate of two strains of n. per ... | 1986 | 3490015 |
| growth-enhancing effects of culture filtrates of sputum isolates on the l-forms of haemophilus influenzae. | the growth-enhancing effects of culture filtrates of respiratory pathogenic bacteria, including haemophilus influenzae, as well as normal floral bacteria other than neisseria perflava and branhamella catarrhalis on l-forms of h. influenzae were examined in vitro, using five species of major respiratory pathogenic bacteria and seven species of normal floral bacteria commonly isolated from the sputum of patients with chronic respiratory tract infections. the growth-enhancing factor(s) was present ... | 1986 | 3490016 |
| in vitro activity and beta-lactamase stability of two oral cephalosporins, ceftetrame (ro 19-5247) and cefetamet (ro 15-8074). | ceftetrame (ro 19-5247) and cefetamet (ro 15-8074), two new orally administered aminothiazolyl imimomethoxy cephalosporins, inhibited hemolytic streptococci and streptococcus pneumoniae at less than or equal to 0.5 micrograms/ml but were less active against staphylococci than were cephalexin and cefaclor. they did not inhibit s. faecalis, s. faecium, listeria monocytogenes, corynebacterium jk species, or pseudomonas aeruginosa. haemophilus influenzae, branhamella catarrhalis, and neisseria gonor ... | 1986 | 3490827 |
| beta-lactamase production in the upper respiratory tract flora. | in order to determine the recovery rate of species of the genera haemophilus and moraxella (including subgenus branhamella) from the upper respiratory tract and the incidence of beta-lactamase production within these genera, cultures were made of nose and throat swab specimens and adenoid tissue in 50 children undergoing adenoidectomy. haemophilus influenzae was isolated from 92% of the children. all children harboured strains of haemophilus spp. and in 46%, at least one strain produced the tem- ... | 1986 | 3490974 |
| disk diffusion susceptibility of branhamella catarrhalis and relationship of beta-lactam zone size to beta-lactamase production. | we tested 231 isolates of branhamella catarrhalis for beta-lactamase production and drug susceptibility by the national committee for clinical laboratory standards disk diffusion method. the nitrocephin disk (cefinase) identified beta-lactamase in 98% of the enzyme-producing strains, and a zone diameter of inhibition of less than or equal to 29 mm for penicillin correctly predicted the presence of beta-lactamase in 99% of the isolates. no resistance to erythromycin, tetracycline, trimethoprim-su ... | 1986 | 3492178 |
| in vitro activity of amoxicillin plus clavulanic acid against haemophilus influenzae and branhamella catarrhalis. | the in vitro activity of amoxicillin in the presence of clavulanic acid against clinical isolates of haemophilus influenzae and branhamella catarrhalis was assessed in comparison with ampicillin, amoxicillin, cefaclor and erythromycin. the isolates were selected so as to yield equal numbers of beta-lactamase producing and non-beta-lactamase producing strains of the two species. mics obtained by agar dilution indicated that amoxicillin in the presence of clavulanic acid was the most active of the ... | 1986 | 3492374 |
| a 2-year survey of branhamella catarrhalis in a general hospital. | during a 2-year period, 143 strains of branhamella catarrhalis were recovered from 7929 respiratory tract specimens (mainly sputa) sent for routine microbiological investigations at a 500 bed general hospital. the incidence of beta-lactamase positive strains increased from 2.7% in 1983 to 40% of isolates in the last 5 months of 1984; this increase continued in the early months of 1985. forty-four strains of bran. catarrhalis recovered from 35 patients were considered on laboratory generated data ... | 1986 | 2873174 |
| hospital-acquired bronchopulmonary infection in premature infants due to branhamella catarrhalis. | 1986 | 2873180 | |
| methicillin-resistant branhamella catarrhalis. | 1986 | 2873186 | |
| branhamella catarrhalis. new methods of bacterial diagnosis. | a total of 176 strains identified as branhamella catarrhalis were isolated from various clinical specimens, mainly sputum (71), pharynx (49), eye (24), nose (11), ear (6) and tracheal aspirate (7). b. catarrhalis appeared as gram-negative cocci in white colonies which were oxidase- and catalase-positive and which did not produce acidification of sugars. the 3 related species, neisseria caviae, n. ovis and n. cuniculi were also white but the 'true asaccharolytic neisseria' studied presented a yel ... | 1986 | 2874008 |
| branhamella catarrhalis chest infections. | 1986 | 2874292 | |
| distribution of an antigenically related iron-regulated protein among the neisseria spp. | several iron-regulated proteins of neisseria gonorrhoeae have been reported. one of these, a 37,000-molecular-weight protein (37k protein), appears to be common to all gonococcal isolates. recently, the occurrence of a similar protein has also been noted in n. meningitidis. the gonococcal 37k protein has been purified and used to produce both rabbit monospecific antiserum and murine monoclonal antibodies. using these antibody reagents, we analyzed 57 strains from nine species of neisseria and th ... | 1986 | 3941006 |
| pseudogonococcal ophthalmia neonatorum caused by branhamella catarrhalis. | 1986 | 3945559 | |
| branhamella catarrhalis as a lower respiratory tract pathogen in patients with chronic lung disease. | to determine the possible role of branhamella (formerly neisseria) catarrhalis as a respiratory pathogen, we screened quality sputa (defined by cellular criteria) that showed numerous gram-negative cocci on gram's stain for the presence of b catarrhalis. in an eight-month period, 52 isolates of b catarrhalis were identified in adults attending a hospital for chest diseases. during this period b catarrhalis was the third most common potential pathogen isolated from sputa. twenty-two patients (42% ... | 1986 | 3963981 |
| the iga subclass responses of human lymphocytes to b-cell activators. | the induction of iga synthesis in normal peripheral blood lymphocytes cultured in the presence of 5 different b-cell activators was studied by immunofluorescence using monoclonal antibodies to the two subclasses. the surface phenotype of normal cells after overnight culture in the absence of mitogen showed a mean ratio iga1:iga2 of 2.7:1; cells with cytoplasmic iga were very rare. results obtained on different donors after stimulation showed considerable variation; iga1 was the predominant subcl ... | 1986 | 3542813 |
| microbial flora of the eyes of cattle. | the bacteria and mycoplasma occurring in the eyes of normal healthy calves were monitored in three groups of animals from purchase at about one week old to slaughter at about 15 months old. non-haemolytic moraxella bovis, branhamella catarrhalis and mycoplasma bovoculi were all isolated regularly, though their seasonal occurrence varied. the significance of these findings with respect to infectious bovine keratoconjunctivitis is discussed. | 1986 | 3716161 |
| branhamella catarrhalis: significance in pulmonary infections and bacteriological features. | a three-month survey revealed 29 patients at our hospital with symptoms of acute pulmonary infection, from whom branhamella catarrhalis was isolated from lower respiratory tract specimens, in 18 cases in pure culture. approximately 2% of all respiratory tract specimens examined during the period yielded growth of b. catarrhalis. all except one patient suffered from chronic pulmonary disease, notably chronic bronchitis. a phenotypic comparison was made between 55 strains of b. catarrhalis, of whi ... | 1986 | 3728028 |
| symposium on branhamella catarrhalis. brockham park, surrey, 17-18 october, 1985. | 1986 | 3732079 | |
| bronchopulmonary infection due to b. catarrhalis. clinical features and therapeutic response. | a study was made of the clinical features and therapeutic response of 144 patients from whose sputum branhamella catarrhalis was isolated. typically, features of bronchopulmonary infection with cough productive of moderate amounts of purulent sputum, fever and dyspnoea were present. of 74 patients who were infected in the community, 50 required hospital admission. nosocomial infection occurred in the remaining 70 patients. most patients had chronic pulmonary diseases or carcinoma bronchus; pneum ... | 1986 | 3732080 |
| otitis media and sinusitis in children. role of branhamella catarrhalis. | otitis media and sinusitis are among the most common diseases of childhood and various treatment approaches have been advocated. this review focuses on current experience in pittsburgh, both in terms of our methods of patient management and the changing aetiology of the underlying diseases. special reference is made to the role played by branhamella catarrhalis and the emergence of beta-lactamase-producing strains. results from recently completed clinical trials would suggest that antibacterial ... | 1986 | 3732081 |
| identification and antimicrobial susceptibility testing of branhamella catarrhalis in united states laboratories, 1983-1985. | 1986 | 3732082 | |
| serological identification of branhamella catarrhalis. serological evidence for infection. | a protein antigen--p-antigen--characteristic of branhamella catarrhalis has been described. precipitating antibodies against this antigen occur in a majority of healthy human sera; serological evidence for a pathogenic role of b. catarrhalis is accumulating. the occurrence of complement-fixing antibodies has been demonstrated during bronchopulmonary infection with b. catarrhalis and in maxillary sinusitis. increases in antibody titres assessed by an enzyme-linked immunosorbent assay (elisa) tech ... | 1986 | 3732083 |
| branhamella catarrhalis respiratory infections in the netherlands. | in the southern netherlands, branhamella catarrhalis can be cultured from sputum in more than 20% of patients with purulent lower respiratory tract infections and approximately 40% of strains produce beta-lactamase. with increasing resistance to co-trimoxazole (10%) and erythromycin (6%) this produces many treatment problems, particularly in general practice. recent results in the treatment of b. catarrhalis respiratory infections with newer antimicrobial agents and new combinations of beta-lact ... | 1986 | 3732084 |
| branhamella catarrhalis as an indirect pathogen. | in 7 patients with bronchopulmonary infections, treatment with penicillin antibiotics failed to eradicate haemophilus influenzae or streptococcus pneumoniae which were sensitive to the antibiotic used. the sputum of these patients contained both the pathogen and beta-lactamase-producing branhamella catarrhalis. no antibacterial activity was detectable in sputum samples obtained from patients receiving a penicillin antibiotic. this suggests that b. catarrhalis can act as an indirect pathogen, pro ... | 1986 | 3732085 |
| ly164846 in vitro antimicrobial activity testing, including disk diffusion susceptibility tests using 30-microgram disks. | a new oral cephalosporin, ly164846 (eli lilly & co., indianapolis, ind.), was found to have a unique antimicrobial spectrum confined to methicillin-susceptible staphylococcus spp., streptococci (except enterococcus spp.), haemophilus influenzae, branhamella catarrhalis, and some anaerobes. cephalothin in vitro tests (30-microgram disks or dilution) can represent ly164846 for laboratory testing if comparable interpretive breakpoints are applied to strains within the spectrum of ly164846. organism ... | 1986 | 3755018 |
| defined medium for moraxella (branhamella) catarrhalis. | a defined medium for growth of 24 strains of moraxella (branhamella) catarrhalis was devised. this medium (medium b4) contains sodium lactate as a partial carbon source, proline as both a partial carbon source and a partial nitrogen source, aspartate as a partial nitrogen source, and the growth factors arginine, glycine, and methionine. either aspartate, glutamate, or proline could serve as sole nitrogen source, but growth occurred at a significantly better rate if proline was present together w ... | 1986 | 3767360 |
| moraxella catarrhalis: antibiotic susceptibility with special reference to trimethoprim. | 1986 | 3771428 | |
| doxycycline in respiratory infections: a re-assessment after 17 years. | seventeen years after a previous study of doxycycline in acute purulent exacerbations of chronic bronchitis, a similar investigation was repeated. forty patients with bacteriologically proven infections were given 100 mg doxycycline twice daily (by mouth) for ten days. the clinical results in branhamella catarrhalis infections were excellent as were those with streptococcus pneumoniae, but one patient developed septicaemia with a resistant pneumococcus while under therapy. treatment was unsucces ... | 1986 | 3771434 |
| [adherence of branhamella catarrhalis to human pharyngeal cells: relation between adherence in vitro and chronic respiratory infections]. | 1986 | 3773367 | |
| branhamella catarrhalis pneumonia in patients with immunoglobulin abnormalities. | the importance of branhamella catarrhalis pneumonia has only recently been appreciated. predisposing underlying illness associated with this organism have not yet been clarified. we report five cases of branhamella catarrhalis pneumonia occurring in patients with diseases associated with documented quantitative immunoglobulin deficiencies. normal immunoglobulins appear to be important host defense mechanisms in preventing infection with this organism. | 1986 | 3775462 |
| in vitro activities of ro 19-5247 and ro 15-8074, new oral cephalosporins. | the in vitro activities of two new oral cephalosporins, ro 19-5247 and ro 15-8074, were compared with the in vitro activities of cefuroxime, cefaclor, amoxicillin-clavulanate, trimethoprim-sulfamethoxazole (tmp-smz), and doxycycline against a variety of bacterial species. mic50s (mics required to inhibit 50% of strains) of ro 19-5247 were less than or equal to 0.13 micrograms/ml for streptococci (except streptococcus faecalis) and haemophilus influenzae; 0.25 to 2 micrograms/ml for most strains ... | 1986 | 3777906 |
| [branhamella catarrhalis respiratory tract infections]. | 1986 | 3795526 | |
| efficacy and safety of ciprofloxacin in patients with respiratory infections in comparison with amoxycillin. | ciprofloxacin and amoxycillin were compared in the treatment of respiratory infections (pneumonia, acute bronchitis, exacerbation of chronic lung disease) in a study of 48 patients randomly assigned to ten days treatment with standard doses of either drug. forty-eight patients were evaluated, 26 in the ciprofloxacin group and 22 in the amoxycillin group. the response to therapy was judged by clinical and bacteriological criteria. ciprofloxacin was as effective as amoxycillin with a successful ou ... | 1986 | 3804901 |
| lower respiratory tract infection due to branhamella catarrhalis, two case reports. | we describe two cases of lower respiratory tract infection due to branhamella catarrhalis in elderly patients. the diagnosis was confirmed by isolation of the organism from the sputa in pure growth and also by response to treatment with appropriate antibiotics. both patients had predisposing factors: one had chronic bronchial asthma and was also on corticosteroids during the illness and the other had chronic obstructive lung disease. previously reported cases are reviewed. | 1986 | 3810847 |
| branhamella catarrhalis: a respiratory pathogen in children? | 1986 | 3463283 | |
| the comparative in-vitro activity of eight newer quinolones and nalidixic acid. | the in-vitro antibacterial activity of nalidixic acid and the 4-quinolones, ciprofloxacin, norfloxacin, enoxacin, ofloxacin, pefloxacin, a-56619, a-56620 and ci-934 was assessed by determination of mics. the 4-quinolones were all highly active against most isolates of enterobacteriaceae, including nalidixic acid-resistant strains. ciprofloxacin (mics 0.002-2 mg/l) was the most active and a-56619 (mics 0.008-32 mg/l) was the least active. a-56619, a-56620, ofloxacin, ciprofloxacin and ci-934 were ... | 1986 | 3468100 |
| branhamella catarrhalis, a respiratory tract pathogen. | 1986 | 3469976 | |
| branhamella catarrhalis--an emerging human pathogen. | 1986 | 3514103 | |
| [respiratory tract infections--clinical results with ofloxacin]. | in an open clinical trial, out-patients with respiratory tract infections were given 200 mg ofloxacin b. i. d. orally. 36 had acute bronchitis and pneumonia was diagnosed in 44. the average duration of therapy was nine days for bronchitis and 12 days for pneumonia. in the sputum of bronchitis patients, haemophilus influenzae (n = 25), streptococcus pneumoniae (n = 18), branhamella catarrhalis (n = 2) and pasteurella multocida (n = 1) were isolated. 17 h. influenzae and 12 s. pneumoniae were elim ... | 1986 | 3514472 |
| lack of immunoglobulin a1 protease production by branhamella catarrhalis. | clinical isolates of branhamella catarrhalis from the sputum of 20 patients with acute bronchopulmonary infection were examined for synthesis of immunoglobulin a1 protease by immunoelectrophoresis. ten strains produced beta-lactamase, and 10 were beta-lactamase negative. none of the strains demonstrated immunoglobulin a1 protease activity despite the fact that three different culture media were used. | 1986 | 3516884 |
| significance of the sulfonamide component for the clinical efficacy of trimethoprim-sulfonamide combinations. | the reasons for combining trimethoprim (tmp) with sulfonamides (sul) are still mainly theoretical but are supported by results from experimental infections and treatment of specific pathogens in humans, such as branhamella catarrhalis, neisseria gonorrhoeae, brucella, nocardia asteroides and perhaps bordetella pertussis and chlamydia trachomatis. addition of sul to tmp confers a therapeutic advantage also in patients with complicated urinary tract infection but probably not in young women with a ... | 1986 | 3518051 |
| amoxycillin-clavulanic acid combination in bronchopulmonary infection due to beta-lactamase-producing branhamella catarrhalis. preliminary report. | since 1978 we have taken an interest in lower respiratory tract infections associated with branhamella catarrhalis in christchurch, new zealand. in a preliminary trial, 20 patients with bronchopulmonary infection caused by beta-lactamase-producing b. catarrhalis were treated with a combination tablet of amoxycillin 500 mg and clavulanic acid 125 mg ('augmentin') 3 times daily for 5 days. sputum cultures were negative for b. catarrhalis within 3 days in all patients. two of 7 patients whose sputu ... | 1986 | 3525087 |
| a randomized controlled trial of amoxicillin plus clavulanate compared with cefaclor for treatment of acute otitis media. | we performed a randomized controlled trial of amoxicillin plus clavulanate versus cefaclor for treatment of acute otitis media. total daily doses given in three divided doses were 40 mg/kg amoxicillin plus 10 mg/kg clavulanate, and 40 mg/kg cefaclor. pathogens were eradicated from the middle ear exudate after 3 to 6 days of therapy in 35 (97%) of 36 patients given amoxicillin-clavulanate compared with 24 (75%) of 32 given cefaclor (p = 0.028). when analysis was restricted to patients with positi ... | 1986 | 3534203 |
| clinical evaluation of the vitek neisseria-haemophilus identification card. | a clinical evaluation of the vitek neisseria-haemophilus identification (nhi) card (vitek systems, inc., hazelwood, mo.) was performed with 480 clinical isolates and stock strains of neisseria spp., haemophilus spp., and other fastidious microorganisms included in the data base of the system. identifications obtained with the nhi card were compared with those determined by conventional methods. the card identified 83.2% of 244 neisseria spp. and branhamella catarrhalis, 54.9% of 164 haemophilus ... | 1987 | 3539996 |
| fatal branhamella catarrhalis pneumonia. | 1987 | 3475613 | |
| penetration of ofloxacin into bronchial secretions. | the penetration of ofloxacin into bronchial secretions was evaluated in 16 patients after administration of a single oral dose of ofloxacin 400mg. bronchial secretions were aspirated at bronchoscopy after 1 to 6 hours and serum was collected simultaneously. ofloxacin concentrations were measured by a microbiological assay method. considerable individual variations in serum and bronchial aspirate concentrations were recorded: bronchial aspirate concentrations varied between 1.1 mg/l and 4.5 mg/l ... | 1987 | 3481325 |
| the in-vitro activity of roxithromycin, a new macrolide antibiotic, in comparison with that of erythromycin. | a study was made of the in-vitro activity of roxithromycin in comparison with that of erythromycin on selected recent clinical isolates of a wide range of organisms. minimum inhibitory concentrations (mics) were determined by an agar dilution method with an inoculum of 10(4) cfu. minimum bactericidal concentrations (mbcs) and the effect of ph were determined by a broth dilution method on selected strains. in general the in-vitro activity of roxithromycin mirrored that of erythromycin, but it was ... | 1987 | 3428135 |
| [the study of flomoxef in the pediatric field]. | flomoxef (fmox; 6315-s), a new synthetic oxacephem antibiotic, was studied in the pediatric field and pharmacokinetic and clinical results obtained were summarized below. 1. the activity of fmox against staphylococcus aureus isolated from clinical patients, including latamoxef resistant strains was very high and mic was approximately less than or equal to 0.39 microgram/ml. this mic value was lower than other cephem antibiotics such as cefotaxime, cefotiam, cefmetazole, cefamandole. the distribu ... | 1987 | 3430712 |
| respiratory infections: clinical experiences with the new quinolones. | nearly 300 patients, admitted to hospital with acute purulent exacerbations of chronic respiratory disease, have been treated with various newer quinolones: 26 patients received enoxacin, 50 pefloxacin, 80 ciprofloxacin and 143 ofloxacin. dosages varied from 400 mg once daily to 1000 mg twice daily. orally for five to 10 days. patients were evaluated bacteriologically and clinically before, during and after treatment. nearly all infections associated with haemophilus influenzae and/or branhamell ... | 1987 | 3438151 |
| [clinical evaluations of flomoxef in respiratory tract infections]. | flomoxef (fmox, 6315-s), a new antibacterial drug, was administered to 9 cases with respiratory tract infections for a duration of 8 approximately 16 days at a daily dose of 2 g. diagnosis of these patients were bronchopneumonia 5 cases, chronic bronchitis 3 cases and acute bronchitis 1 case. from transtracheal aspiration several organisms were isolated; haemophilus influenzae was isolated in 3 cases, streptococcus pneumoniae in 3 cases, h. influenzae plus branhamella catarrhalis in 1 case, stre ... | 1987 | 3444019 |
| the aetiology of pneumonia. application of bacterial serology and basic laboratory methods. | the aetiology of community-acquired pneumonia was studied by use of new bacterial and established viral serological methods besides blood culture in 162 patients. evidence for a specific aetiology was obtained in 79 patients (49.4%). the pneumococcus was the most common aetiological agent, identified in 25.6% of cases. other bacteria, haemophilus influenzae, branhamella catarrhalis, neisseria meningitidis and chlamydia spp. were demonstrated in 23.5%, mycoplasma pneumonia in 1.2% and viruses in ... | 1987 | 3819455 |
| the increasing importance of branhamella catarrhalis in respiratory infections. | 1987 | 3547295 | |
| clinical interpretation of beta-lactamase-producing strains of branhamella catarrhalis in sputum gram's stain and culture. | branhamella catarrhalis has been implicated previously as a cause of bronchopulmonary infections. sputum gram's stain and culture results suggesting significant infection with beta-lactamase-producing strains of b. catarrhalis were correlated with a retrospective chart review of eight pediatric and ten adult patients. preexisting pulmonary disease was observed in 12 patients; 5 had a history of aspiration; and 13 were intubated. clinically, ten patients had pneumonia, five had bronchitis, and th ... | 1987 | 3548321 |
| efficacy and safety of oral ciprofloxacin in the treatment of serious respiratory infections. | fifty-two patients with serious respiratory infections were treated with orally administered ciprofloxacin; 42 patients were evaluable for the efficacy analysis and all were evaluable for determining adverse reactions. cures were achieved in 24 patients with infections (14 with bronchitis, 10 with pneumonia) caused by hemophilus influenzae, streptococcus pneumoniae, or branhamella catarrhalis, and pathogens were rapidly eradicated from respiratory secretions. seventeen patients had infections (s ... | 1987 | 3555037 |
| branhamella catarrhalis peritonitis in a continuous ambulatory peritoneal dialysis patient. | 1987 | 3561626 | |
| branhamella catarrhalis keratitis. | branhamella catarrhalis, formerly known as neisseria catarrhalis, has structural similarities to neisseria gonorrhoeae, but is generally considered to be nonpathogenic. we studied the clinical and laboratory data of four previously reported cases and six additional cases of b. catarrhalis keratitis. all patients had a predisposing ocular or systemic condition, or both. there were various clinical characteristics, but in most cases the infiltrate occurred in the central or paracentral cornea. a p ... | 1987 | 3565517 |
| branhamella catarrhalis infection imitating gonorrhea in a man. | 1987 | 3574393 | |
| acute bacterial exacerbations in bronchitis and asthma. | symptomatic exacerbations are frequent problems in the management of chronic bronchitis and bronchial asthma. identification of a bacterial etiology as the cause of specific exacerbations should be based on changes in clinical symptoms and documentation of significant bronchial bacterial flora and a neutrophilic inflammatory response. most acute bacterial exacerbations in patients with bronchitis or asthma are caused by hemophilus influenzae, streptococcus pneumoniae, or branhamella catarrhalis. ... | 1987 | 3578322 |
| bacterial infections in adult patients with the acquired immune deficiency syndrome (aids) and aids-related complex. | sixty-four episodes of bacterial infection were identified over a 44-month period in 16 of 28 patients with the acquired immune deficiency syndrome (aids) and 14 of 31 patients with aids-related complex. nineteen of the 30 infected patients were parenteral drug abusers, 10 were from caribbean islands and had no identified risk factor, and one was a homosexual male. fourteen patients had 21 episodes of community-acquired pneumonia: streptococcus pneumoniae (10), haemophilus influenzae (three), ot ... | 1987 | 3578359 |
| three methods for detecting synergy between sulphamethoxazole and trimethoprim against branhamella catarrhalis. | 1987 | 3583976 | |
| [susceptibility of bacteria isolated from the patients with lower respiratory tract infections to antibiotics (1984)]. | bacterial isolates from patients with pulmonary infections have been collected over the last 4 years in collaboration with investigators at 14 hospitals in various parts of japan to study isolation frequency of pathogens from patients and drug susceptibilities of these isolates. possible causative pathogens mainly isolated from sputum of patients with lower respiratory tract infections were collected during a period from september 1984 to march 1985. we first determined types of respiratory dise ... | 1987 | 3586339 |
| [importance of diagnosing infections caused by branhamella catarrhalis]. | 1987 | 3586765 | |
| pediatric gastroenteritis in primary care and in hospitalized patients. | one-hundred and fifty-seven consecutive children below seven years of age (primary care n = 48, hospitalized patients n = 109) with acute gastroenteritis of assumed infectious origin were studied. rotavirus was demonstrated by electron microscopy of faeces in 44% of all patients. the occurrence of rotavirus among patients in primary care, 15%, was significantly lower than among hospitalized patients, 57% (p less than 0.01). adenovirus was isolated in six per cent and enterovirus in two per cent ... | 1987 | 3589234 |
| comparative in vitro activity of the new oral cephalosporin bmy-28100. | using a broth microdilution method, the in vitro activity of bmy-28100 against 365 clinical strains of commonly isolated bacteria was determined. bmy-28100 showed good activity against streptococci, methicillin-susceptible staphylococci, salmonella spp., shigella spp., and beta-lactamase producing branhamella catarrhalis and haemophilus influenzae. against susceptible strains of these organisms, bmy-28100 showed activity comparable to that of penicillin g, ampicillin, co-trimoxazole, erythromyci ... | 1987 | 3595580 |
| [refractory respiratory tract infections. 9. chemotherapy of recent respiratory tract infections. a. branhamella catarrhalis infection]. | 1987 | 3599486 | |
| therapeutic failure due to branhamella catarrhalis in pneumoccal pneumonia. | 1987 | 3608615 | |
| [smoking and lower respiratory tract infection]. | cigarette smoking exerts deleterious effects not only on the respiratory tract, but also on the lung's parenchyma. the fev is reduced in heavy chronic smokers. persistent smoking has an unfavourable influence on mucociliary activity. according to the results of recent research almost 8 million people in the u.s. were suffering from chronic bronchitis in 1981. there is a direct correlation between the number of cigarettes smoked, over what period of time, and the incidence of chronic bronchitis. ... | 1987 | 3610332 |
| pneumonia associated with branhamella catarrhalis in infants. | 1987 | 3615071 | |
| bacterial tracheitis caused by branhamella catarrhalis. | 1987 | 3615072 | |
| relapse of acute purulent otitis media: antibiotic sensitivities of nasopharyngeal pathogens. | the present investigation was conducted to find out if a relapse of acute purulent otitis media is associated with a decreased sensitivity of nasopharyngeal pathogens to commonly used antimicrobial agents. all but one of 63 children with relapse included in this study yielded one or more of the classical middle ear pathogens (streptococcus pneumoniae, haemophilus influenzae, branhamella catarrhalis, s. pyogenes) in their nasopharynx (nph) secretions. s. pneumoniae was the predominating isolate f ... | 1987 | 3616495 |
| a note on hydrolysis of tributyrin by branhamella and neisseria. | sixty-three strains of branhamella and neisseria were tested by two methods for their ability to hydrolyse glycerol tributyrate. after the conventional plate test, gas liquid chromatographical (glc) analysis of the agar medium was carried out to detect the hydrolysis product, butyric acid, and other volatile fatty acids. all strains of branhamella catarrhalis, neisseria caviae, n. cuniculi and n. ovis but no other neisseria spp. gave positive results with the conventional test. with glc, however ... | 1987 | 3624107 |
| effect of inoculum size on results of macrotube broth dilution susceptibility tests with branhamella catarrhalis. | the effect of inoculum size on the results of macrotube broth dilution mics was assessed with 15 strains of branhamella catarrhalis versus 22 antimicrobial agents. the study isolates included five beta-lactamase-negative strains, five strains that produced beta-lactamase and for which ampicillin mics were high, and five beta-lactamase-producing strains for which ampicillin mics were low. an inoculum effect was observed only with strains in the last group when tested versus the following antimicr ... | 1987 | 3624453 |
| [bacteriological study of acute otitis media in children. therapeutic consequences]. | one hundred children presenting with acute otitis media underwent a bacteriological study of otitis exudate over a 18 month period. the bacteria found were as follows: streptococcus pneumoniae (24), haemophilus influenzae (19), staphylococcus aureus (12), streptococcus pyogenes (7), branhamella catarrhalis (3), and 18 gram negative bacilli (including 7 pseudomonas aeruginosa and 11 enterobacteriaceae). one pathogenic bacterium was isolated in 56 cases, 2 or more in 12 cases and none in 32 cases. ... | 1987 | 3650065 |
| in vitro susceptibility of upper respiratory tract pathogens to 13 oral antimicrobial agents. | an in vitro comparison of the activities of 13 oral antimicrobial agents against clinical isolates of bacteria commonly responsible for causing upper respiratory tract infections was performed. with regard to haemophilus influenzae, beta-lactamase-negative strains were susceptible to amoxycillin, augmentin, cefaclor, erythromycin, trimethoprim, cotrimoxazole and tetracycline, with cl 284,635 being the most active agent. with the exception of amoxycillin these drugs were also active against beta- ... | 1987 | 3660122 |
| in vitro activity of a new broad spectrum, beta-lactamase-stable oral cephalosporin, cefixime. | cefixime is a new orally absorbed iminomethoxy, aminothiazolyl cephalosporin. it inhibits the majority, 90%, of streptococcus pneumoniae, streptococcus pyogenes, branhamella catarrhalis, haemophilus influenzae, escherichia coli, klebsiella pneumoniae, proteus mirabilis and neisseria gonorrhoeae at concentrations less than or equal to 0.25 micrograms/ml. it inhibits 90% of the other members of the enterobacteriaceae at concentrations less than 1 microgram/ml, with the exception of some strains of ... | 1987 | 3696836 |
| bacteriologic and clinical efficacy of cefixime compared with amoxicillin in acute otitis media. | the ability of cefixime or amoxicillin to eradicate causative pathogens was evaluated in 140 infants and children with acute otitis media with effusion. when pretherapy and on-therapy bacteriologic cultures were used, success was defined as elimination of pathogens regardless of clinical improvement. parent compliance with administration instructions was closely monitored. cefixime was administered daily or twice daily and because results on the two dosage regimens did not differ, data were comb ... | 1987 | 3696839 |
| characterisation of branhamella catarrhalis and differentiation from neisseria species in a diagnostic laboratory. | to distinguish branhamella catarrhalis from neisseria species a study of 140 strains was made on simple laboratory media, with particular reference to deoxyribonuclease (dnase) production, superoxol reaction, and growth characteristics. all 97 clinical isolates of b catarrhalis (58 of which were beta-lactamase positive) and eight strains of b catarrhalis from the national collection of type cultures were dnase positive and superoxol positive. none grew on modified new york city medium, modified ... | 1987 | 2826546 |
| activation of b chronic lymphocytic leukaemia cells by branhamella catarrhalis. | cells from the blood of patients with chronic lymphocytic leukaemia were cultured in the presence of two polyclonal activators of human b cells, the bacteria branhamella catarrhalis (bc) and staphylococcus aureus cowan 1 (sac). although the magnitude of the responses varied, cells from seven of the eight patients studied were induced to proliferate in response to bc. in contrast, the response to sac was low or negligible in seven of the eight patients, and only one patient responded well to this ... | 1987 | 3493206 |
| acute otitis media caused by branhamella catarrhalis: biology and therapy. | since 1980, we have observed an epidemic of otitis media caused by branhamella catarrhalis. this event was characterized by studying the nasopharyngeal colonization of infants and children with b. catarrhalis and the clinical presentation and therapeutic outcome of acute otitis media caused by this organism. pharyngeal colonization with b. catarrhalis was commoner in winter than summer. b. catarrhalis was present in middle-ear fluid (mef) of 17% of children with otitis media, and was commoner in ... | 1987 | 3493519 |
| susceptibility of branhamella catarrhalis to sulphamethoxazole and trimethoprim. | fifty strains of branhamella catarrhalis were examined for susceptibility to sulphamethoxazole, trimethoprim and a combination of the two by determinating minimum inhibitory concentrations (mics) and fractional inhibitory concentrations (fics). all strains were susceptible to sulphamethoxazole and resistant to trimethoprim. on the basis of the mic results it was predicted that greater synergy between sulphamethoxazole and trimethoprim would be observed with approximately equal proportions of eac ... | 1987 | 3494008 |
| amoxycillin/clavulanate in acute purulent exacerbations of chronic bronchitis. | twenty patients, all admitted to hospital with acute purulent exacerbations of chronic bronchitis associated with haemophilus influenzae, streptococcus pneumoniae or beta-lactamase producing branhamella catarrhalis were treated twice daily for ten days with amoxycillin/clavulanate. ten patients were first given 1000 mg amoxycillin with 200 mg potassium clavulanate intravenously bd for three days, before crossing to the standard oral regimen of 1000 mg amoxycillin + 250 mg potassium clavulanate b ... | 1987 | 3494724 |
| [acute sinusitis in adults]. | an average of 1.4% of the more than 30,000 participants in a treatment study were diagnosed as having acute sinusitis. 62% of all cases of sinusitis arose in patients aged between 15 and 44 years. treatment with antibiotics is indicated in purulent sinusitis whilst non-purulent sinusitis is treated either with local or systemic antiphlogistic agents. the secondary bacterial infection is usually caused by haemophilus influenzae, streptococcus pneumoniae and anaerobic bacteria. in scandinavia thes ... | 1987 | 3497108 |
| comparative antibacterial activity of the new oral cephalosporin bmy-28100. | the in vitro activity of bmy-28100 was compared with that of four other oral cephalosporins against gram-positive cocci, branhamella catarrhalis and haemophilus influenzae. bmy-28100 showed 5-20 times better activity against staphylococci and streptococci. methicillin-resistant staphylococci and enterococci were resistant to the drug. branhamella catarrhalis and haemophilus influenzae strains were moderately susceptible. time-kill curve studies showed bmy-28100 to be equally as active as benzylp ... | 1987 | 3497804 |
| detection of beta-lactamase activity among clinical isolates of branhamella catarrhalis with six different beta-lactamase assays. | a total of 74 different clinical isolates of branhamella catarrhalis were examined for their ability to produce beta-lactamase by six different beta-lactamase assays. these included a conventional tube and disk test, in which the chromogenic cephalosporin nitrocefin was used as a substrate; a disk procedure, in which pyridinium-2-azo-p-dimethylanaline cephalosporin was used as a substrate; broth and disk acidometric methods; and a conventional tube iodometric assay. a total of 58 of the study is ... | 1987 | 3497942 |
| in vitro and in vivo antibacterial activities of t-2588, a new oral cephalosporin, compared with those of other oral beta-lactam antibiotics. | t-2588, the pivaloyloxymethyl ester of t-2525, [6r, 7r]-7-[(z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetoamido] -3- [(5-methyl-2h-tetrazol-2-yl)methyl]-3-cephem-4-carboxylic acid, is a new oral cephalosporin. t-2525 had a widely expanded antibacterial spectrum against gram-negative and gram-positive bacteria. t-2525 was more active in vitro than cefaclor, cephalexin, and amoxicillin against members of the family enterobacteriaceae and branhamella catarrhalis. moreover, it exhibited superior in ... | 1987 | 3499115 |
| [increasing role of branhamella catarrhalis in bronchopulmonary pathology in adults]. | 1987 | 2955369 | |
| respiratory tract infections due to branhamella catarrhalis and neisseria species. | 1987 | 3151758 | |
| sputum microbiology in a district general hospital. the role of branhamella catarrhalis. | evidence is presented that supports the view that branhamella catarrhalis has a pathogenic role in chronic chest disease, similar in many respects to haemophilus influenzae. it was isolated from 4% of sputum specimens (compared to 10% for haemophilus influenzae). fifty-three per cent produced beta-lactamase, and all were resistant to trimethoprim. the relevance of these findings to antibiotic treatment is discussed. | 1987 | 3130089 |
| branhamella catarrhalis conjunctivitis. | eleven cases of branhamella catarrhalis conjunctivitis have been reported. in four recent studies that examine the microbial etiology of ophthalmia neonatorum, b catarrhalis was identified only twice in 1,299 cases. however, diagnosis by gram stain in some and previous antibiotic therapy in others may have resulted in underdiagnosis of b catarrhalis and inaccurate diagnosis as gonococcal ophthalmia. | 1987 | 3299731 |