Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| judging the ethical merit of clinical trials: what criteria do research ethics board members use? | 1994 | 11654136 | |
| norplant entered canada through the back door. | three women's groups registered their concerns and recommendations about the use of norplant in canada, where it was approved for use in november, 1993. the national action committee on the status of women had the following reservations: 1) norplant requires trained personnel for its insertion and removal (both minor surgical procedures), which makes it controlled by the provider; 2) there is a potential for misuse without adequate informed consent, especially among welfare recipients, disabled ... | 1994 | 12318719 |
| nickel in the terrestrial environment. | this paper provides an overview of nickel concentrations in the terrestrial environment especially as it relates to exposure of the metal to humans and animals through food. the information includes a review of reports published in the scientific literature substantially supplemented with data obtained across the province of ontario, canada. the topics covered include background levels and levels of nickel measured in a number of different types of biota exposed to environmental contamination. t ... | 1994 | 8029689 |
| do scientific and scholarly codes of ethics take social issues into account? | 1995 | 11654230 | |
| the right to procreate: when rights claims have gone wrong. | 1995 | 11654471 | |
| the law and ethics in relation to dentists treating hiv-positive patients: two recent court cases. | two recent canadian judgements regarding the application of human rights legislation to dentistry and hiv-seropositive patients are summarized and discussed. in the ontario case of jerome v. demarco, the ontario human rights tribunal found that seropositivity constitutes a "handicap" under human rights legislation. however, the tribunal dismissed the claim by a seropositive patient that he had been illegally discriminated against by a dentist who, on learning the patient was seropositive, delaye ... | 1995 | 7614430 |
| pcb and organochlorine pesticides in canadian human milk--1992. | human milk (497 samples) representing donors from across canada were analyzed for 24 organochlorine pesticides and industrial chemicals and 40 pcb congeners. pcbs, p,p'-dde, hexachlorobenzene (hcb), and trans nonachlor were present in all samples. compared to earlier surveys in canada, concentrations of most residues determined declined, and were lower than those reported recently in european countries. although regional differences were minor, residues of pcbs, p,p'-dde, and trans nonachlor wer ... | 1995 | 7620848 |
| prevalence of human immunodeficiency virus and associated risk behaviour in injection drug users in toronto. | during 1989-90, interviews were conducted with 582 current injection drug users in the city of toronto, 535 of whom also provided blood and/or saliva for anonymous unlinked hiv antibody testing. the rate of seropositivity identified was 4.3% (95% ci 3-6). the subjects were predominantly male, with a mean age of 28.3. the commonest drug of choice was cocaine (70%). forty-six percent of the subjects reported using someone else's needle in the preceding six months, 60% of these indicating that they ... | 1995 | 7671202 |
| canada to set up genome research centre in toronto. | 1995 | 7830754 | |
| what happens to donated blood? | pursuing their chief work--gathering, processing and distributing blood--the blood donor centres of the canadian red cross society follow standard operating procedures like those in place at the ottawa centre. here, recruitment staff and volunteers work to recruit donors to meet needs at a time when the number of donors is falling. when they register, donors must show proof of identity. each receives a permanent identification number that is linked to the numbers assigned to the units of blood e ... | 1995 | 7859200 |
| validation of a decisional conflict scale. | the study objective was to evaluate the psychometric properties of a decisional conflict scale (dcs) that elicits: 1) health-care consumers' uncertainty in making a health-related decision; 2) the factors contributing to the uncertainty; and 3) health-care consumers' perceived effective decision making. the dcs was developed in response to the lack of instruments available to evaluate health-care-consumer decision aids and to tailor decision-supporting interventions to particular consumer needs. ... | 1995 | 7898294 |
| do doctors accurately assess coronary risk in their patients? preliminary results of the coronary health assessment study. | to evaluate the ability of doctors in primary care to assess risk patients' risk of coronary heart disease. | 1995 | 7728035 |
| a respiratory outbreak due to parainfluenza virus type 3 in a home for the aged--ontario. | 1995 | 7749396 | |
| an influenza a outbreak in an ontario nursing home: estimates of vaccine efficacy. | 1995 | 7749397 | |
| the hiv information project for transfusion recipients a decade after transfusion. | to gather information on which to base decisions about a general notification program for pediatric patients a decade after their receiving transfusions. | 1995 | 7767426 |
| group dynamics training for manned spaceflight and the capsuls mission: prophylactic against incompatibility and its consequences? | on february 7, 1994, four canadian astronauts were sealed off in a hyperbaric chamber at the canadian government's defense and civil institute for environmental medicine in toronto, canada. this space lab training mission lasted seven days and was the first to be conducted with astronauts outside of russia. the objective of this mission was to give canadian astronauts, space scientists and the staff of the canadian space agency (csa), the opportunity to gain first hand experience on preparationa ... | 1995 | 11540989 |
| hiv discrimination case. | 1995 | 8521320 | |
| urban air quality and human health: a toronto perspective. | 1995 | 8556685 | |
| leukemia after irradiation for endometrial cancer in ontario. | in human studies, the risk of leukemia after ionizing radiation has been found to be increased more often than for any other cancer. it is useful to study patients with cancer treated with radiation because exposure can be measured accurately, follow-up may be long, and often a comparable and sizable nonexposed group exists. women with endometrial cancer represent an excellent population for study because they meet these developed leukemia after endometrial. | 1995 | 8625159 |
| an artificial heart with the right connection. | led by dr. tofy mussivand at the university of ottawa heart institute, a team of canadian medical scientists, engineers, economists, physicians and medical devices manufacturers is working to bring a prototype artificial heart closer to clinical trials. key to this effort is the development of an electrical connector that can function for a long period in the harsh environment of the human body. such a connector will enable various components of the artificial heart, such as the internal battery ... | 1996 | 8630841 |
| reducing demand for physician visits through public education: a look at the pilot cold-and-flu campaign in london, ontario. | to estimate the effect of the ontario ministry of health's pilot public-education campaign launched in london, ont., on jan. 15, 1994, to reduce the number of visits to physicians' offices because of cold and flu symptoms. | 1996 | 8634961 |
| canadian patient played key role in uncovering secrets about early-onset alzheimer's disease. | last june, the university of toronto announced that canadian scientists and a team of international researchers had discovered the gene responsible for most cases of early-onset alzheimer's disease. one of the key players in that discovery had died just 3 months earlier. frances hodge, who participated in a battery of tests for the 20 years she lived with the disease, helped lead researchers to gene s182--and an ember of hope for future generations. | 1996 | 8634971 |
| invasive group a streptococcal infections in ontario, canada. ontario group a streptococcal study group. | several reports suggest that the incidence of invasive group a streptococcal infections, including streptococcal toxic shock syndrome and necrotizing fasciitis, is increasing. | 1996 | 8684408 |
| pharmacists' provision of continuity of care to patients with human immunodeficiency virus infection. | a pharmacy program for providing continuity of care to patients infected with human immunodeficiency virus (hiv) is described. the program was implemented at three practice sites in toronto: a tertiary care teaching hospital; an outpatient community pharmacy that is part of the hospital; and an ambulatory care clinic affiliated with the hospital. an hiv pharmacy practice was established at the hospital in 1993. the community pharmacy serves at least 30% of the hiv-infected patients in ontario wh ... | 1996 | 8744462 |
| invasive infection with streptococcus iniae--ontario, 1995-1996. | during december 1995-february 1996, four cases of a bacteremic illness (three accompanied by cellulitis and the fourth with infective endocarditis, meningitis, and probable septic arthritis) were identified among patients at a hospital in ontario. streptococcus iniae, a fish pathogen not previously reported as a cause of illness in humans, was isolated from all four patients. all four patients were of chinese descent had a history of preparing fresh, whole fish; three patients for whom informati ... | 1996 | 8769472 |
| the effects of ambient ozone on lung function in children: a reanalysis of six summer camp studies. | studies of children attending summer camps often have observed relationships between daily outdoor ozone (o3) concentrations and decreased lung function that are qualitatively similar to results seen in human chamber studies. the former studies, focusing on the pulmonary effects of o3 and associated pollutants on children under natural conditions of exposure, are potentially of great importance to understanding the public health impact of ambient o3. however, a thorough assessment of the results ... | 1996 | 8820584 |
| canadian health databases relevant to great lakes basin research. | several population-based health databases exist in canada which provide valuable systematic information for facilitating epidemiological evaluation of human health in the great lakes basin. they include the long-established canadian mortality database, a national birth defects registry, a provincial hospitalization database, and provincial and national cancer registry systems. the most recent addition is the national enhanced cancer surveillance system which currently is being implemented to all ... | 1996 | 8843571 |
| streptococcal toxic shock syndrome in dogs. | to determine the clinical, pathologic, and bacteriologic findings in dogs that developed severe invasive infections with group g streptococci (ggs) over a 6-month period in southern ontario. | 1996 | 8870738 |
| sensitive and controversial ethical issues subject of groundbreaking toronto exhibit. | medical research and practice have always posed many ethical dilemmas for scientists and physicians, but technologic advances mean that the questions are becoming even more difficult. that is why an exhibit, a question of truth, that is being prepared at toronto's ontario science centre is so timely. it examines the biases and political climates in which science operates, as well as the relative subjectivity of truth, knowledge and reality. | 1996 | 8943940 |
| psychiatric disability in ontario. | to describe the disability associated with psychiatric disorder in a community sample in order to refine estimates of service need and identify subgroups with greater priority for intervention. | 1996 | 8946079 |
| genetic variation of intestinal fatty acid-binding protein associated with variation in body mass in aboriginal canadians. | we hypothesized that genomic variation affecting the primary amino acid sequence of the intestinal fatty acid-binding protein would be related to variation in body mass index and associated clinical phenotypes in aboriginal canadians. we studied 507 adult native canadians from an isolated community in northern ontario. we found that the frequency of the t54 variant of the intestinal fatty acid-binding protein gene was 0.14 in this sample. the presence of this variant was associated with signific ... | 1996 | 8954037 |
| the canadian human activity pattern survey: report of methods and population surveyed. | the assessment of health risk due to environmental contaminants depends upon accurate estimates of the distribution of population exposures. exposure assessment, in turn, requires information on the time people spend in micro-environments and their activities during periods of exposure. this paper describes preliminary results including study methodology and population sampled in a large canadian survey of time-activity patterns. a 24-hour diary recall survey was performed in 2381 households (re ... | 1996 | 9097012 |
| physician impact analysis predictions in ontario hospitals: does the emperor have clothes? | physician impact analysis (pia) is a human resource planning tool used to predict the impact on hospital resources of adding a new or replacement physician to a hospital's medical staff. this article describes the findings of a study which examined the extent to which pias are used in ontario acute care hospitals and the accuracy of pia predictions. the results suggest that although pia appears to be widely used, there is no evidence that it meets the intended policy objective of accurately pred ... | 1996 | 10162423 |
| the ethics of human experimentation: reinventing the research ethics board: proceedings of a national workshop held in ottawa, ontario, march 5-6, 1995. | 1996 | 11654527 | |
| a case study of the labour market status of recent mainland chinese immigrants, metropolitan toronto. | "this article focuses on an analysis of the labour market status of recent mcis [mainland chinese immigrants to canada], taking into account such factors as gender, educational attainment, language proficiency and period of arrival (or length of residence in canada), and uses metropolitan toronto as a case study. the effect of each factor on mcis' labour market status will be analysed separately, followed by two logit models examining the simultaneous effects of the factors and their relative im ... | 1996 | 12292181 |
| physician, heal thyself. | 1997 | 10175714 | |
| justice delayed and denied in biting case. | an hiv-positive transgendered sex worker who bit a police officer on the hand was sentenced to two years, less one day, in a provincial prison. the officer charged the sex worker with aggravated assault since she knew she had hiv and was therefore endangering the officer's life. the officer has since had regular testing, has attended hiv counseling, and has delayed starting a family. he continues to test hiv-negative after eight months. the sex worker served 16 months of her sentence before bein ... | 1997 | 11365295 |
| provision of legal services to persons with hiv or aids: barriers and trends. | canadian hiv/aids legal clinics address their agendas, funding, activities, and observed trends. the hiv & aids legal clinic (ontario) (halco) is profiled in the first of a series. halco is a poverty law clinic for hiv-positive people with limited financial means in ontario. the profile of legal problems handled by halco includes government assistance payments, inadequate or too-expensive housing, wills and substitute decision making, bankruptcy, human rights, prison health issues, employment co ... | 1997 | 11365299 |
| infection control in the orthodontic office in canada. | because of the difficulty of identifying infected persons, current recommendations for infection control are to treat all patients as if they are infected with blood-borne pathogens such as human immunodeficiency virus (hiv) and the hepatitis viruses. dentists' compliance with these recommendations has been investigated previously, however, there are few data related to orthodontists. the objective of this study was to measure the proportion of orthodontists who report the use of recommended inf ... | 1997 | 9294356 |
| the prevalence of positive hepatitis b, hepatitis c, and hiv serology in cornea donors prescreened by medical and social history in ontario, canada. | to determine the prevalence of hepatitis b (hbv), hepatitis c (hcv), and human immunodeficiency virus (hiv) in the serum of cornea donors who had been previously screened by social and medical history by the eye bank of canada, ontario division. | 1997 | 9294680 |
| mycobacterium xenopi infection in patients with human immunodeficiency virus infection. | mycobacterium xenopi is one of the most frequently isolated nontuberculous mycobacteria in ontario, canada. we reviewed the records of 28 human immunodeficiency virus (hiv)-infected patients from whom m. xenopi was isolated between 1982 and 1995. m. xenopi was recovered from respiratory specimens from 24 patients, most of whom had clinical and radiographic evidence of pulmonary disease. however, coexistent pulmonary infection due to other pathogens was found in 17 patients: pneumocystis carinii ... | 1997 | 9332511 |
| the legal implications of the veterinarian's role as a private practitioner and health professional, with particular reference to the human-animal bond: part 2, the veterinarian's role in society. | 1997 | 9332754 | |
| status of trichinella spiralis in domestic swine and wild boar in canada. | evidence of the status of trichinellosis in canada's national swine herd is provided from data acquired through national surveillance programs and from a prevalence study of trichinella in wild boar and domestic swine. more than 500,000 swine tested at abattoirs in ongoing animal health surveys since 1980 and 2 national swine serological surveys (1985 and 1990) showed no evidence of trichinella infection, except for 3 occurrences in a small infected zone in nova scotia. the prevalence study of d ... | 1997 | 9342448 |
| the infection control practices of general dental practitioners. | to investigate the infection control practices of general dentists in ontario in 1994. | 1997 | 9350462 |
| persistence of escherichia coli o157:h7 in dairy cattle and the dairy farm environment. | the persistence of escherichia coli o157:h7 in cattle and the farm environment was investigated on eight ontario dairy farms positive for e. coli o157:h7 in a longitudinal study commenced one year previously. faecal samples from cows, calves, humans, cats, rodents, wild birds, a composite fly sample and numerous composite and individual environmental samples were cultured and tested for verotoxin-producing e. coli (vtec). vtec isolates were serotyped and e. coli o157:h7 isolates were phage typed ... | 1997 | 9363025 |
| causes of death of hiv-infected persons in ottawa, ontario, 1984-1995. | acquired immunodeficiency syndrome (aids) has become a leading cause of death of young men in the united states. with the introduction of prophylaxes and antiretrovirals for opportunistic infection, there have been significant changes in the clinical history of human immunodeficiency virus (hiv) infection. | 1997 | 9382662 |
| low dietary fiber and high protein intakes associated with newly diagnosed diabetes in a remote aboriginal community. | the high prevalence of diabetes mellitus in north american aboriginal populations may be due to recent changes in lifestyle, including the adoption of a high-fat, low-fiber diet. to determine whether fat or fiber intakes were associated with new cases of diabetes, we studied 72% (728/1018) of residents aged > 9 y from a remote aboriginal community in northern ontario using the 75-g oral-glucose-tolerance test and 24-h dietary recall. the mean fat intake of this population (36% of energy) was typ ... | 1997 | 9394701 |
| hepatitis a outbreak in a socially-contained religious community in rural southern ontario. | 1997 | 9397602 | |
| common genomic variation in the apoc3 promoter associated with variation in plasma lipoproteins. | we hypothesized that common genomic variation that affected the expression and/or function of the products of the apoc3, apoe, fabp2, and pon1 genes would be associated with variation in biochemical phenotypes in a previously unstudied human sample. we determined genotypes of functional genomic variants of apoc3, apoe, fabp2, and pon1 in 509 adult aboriginal canadians from an isolated community in northern ontario. we tested for genotype associations with plasma lipoprotein traits. we found that ... | 1997 | 9409252 |
| outbreak of influenza a in an ontario nursing home--january 1997. | 1997 | 9439036 | |
| making our offices universally accessible: guidelines for physicians. | to develop recommendations for office-based physicians who wish to make their offices accessible to all patients. | 1997 | 9068570 |
| the futility of utility: barriers to the development of nursing human resource policies for ontario. | 1997 | 9086966 | |
| the right of dentists to take extra precautions when treating patients known to carry the human immunodeficiency virus. | oral health care providers have taken various positions toward the concept of correct behavior toward and management of patients who are seropositive for human immunodeficiency virus. several tribunal judgments and articles have discussed and analyzed this subject. this article presents a new detailed report and analysis and decision issued by a dental profession panel (tribunal) in ontario, canada. the concepts of universal precautions and antidiscriminatory acts are discussed. | 1997 | 9477869 |
| case costing means, measuring and managing now! the journey traveled by a community hospital. | funding for health care in ontario is moving from global funding to equity funding. in the future, hospitals will be reimbursed for how efficiently they care for their various patient populations. the ontario case costing project (occp) was a joint venture by the ontario hospital association and the ministry of health. incentive for participation in this project was based on the need to assess efficiencies in caring for patient populations in surgical suites and to obtain canadian data. case cos ... | 1997 | 9526309 |
| dental human resource distribution in ontario: a report for 1997. | 1997 | 9879253 | |
| human research beyond the medical model: legal and ethical issues. | advances in medical health depend on non-medical, as well as medical research. when research involves human participants, it raises legal and ethical concerns that have come to be approached by reference to codes of research ethics. many of these are centered on physician-patient relationships and the pursuit of medical science. this article considers a number of issues that arise from research that follows non-medical models of research, and applications of rules of ethical medical research out ... | 1997 | 9573707 |
| management of common musculoskeletal problems: a survey of ontario primary care physicians. | in canada, primary care physicians manage most musculoskeletal problems. however, their training in this area is limited, and some aspects of management may be suboptimal. this study was conducted to examine primary care physicians' management of 3 common musculoskeletal problems, ascertain the determinants of management and compare management with that recommended by a current practice panel. | 1998 | 9580733 |
| absence of association between genetic variation of the beta 3-adrenergic receptor and metabolic phenotypes in oji-cree. | to assess the association between the common missense variant, y64r, in the gene encoding the beta 3-adrenergic receptor, adrb3, and intermediate phenotypes related to obesity and niddm in canadian oji-cree. | 1998 | 9589254 |
| the economic costs of alcohol abuse in ontario. | the abuse of alcohol causes health and social problems, such as sickness, death, injury, pain, suffering and crime. these harms impose an economic burden on society. resources are used or foregone as a consequence of alcohol abuse. this article provides an estimate of the economic cost of alcohol abuse in ontario in 1992. it uses the cost-of-illness method, in particular, the human-capital approach to estimate the prevalence-based economic costs of alcohol abuse. this methodology is consistent w ... | 1998 | 9602474 |
| empirical examination of the ability of children to consent to clinical research. | this study examined the quality of children's assent to a clinical trial. in subjects younger than 9 years of age, understanding of most aspects of the study was found to be poor to non-existent. understanding of procedures was poor in almost all subjects. in addition, voluntariness may have been compromised in many subjects by their belief that failure to complete the study would displease others. if the fact that a child's assent has been obtained is used to justify the exposure of that child ... | 1998 | 9650109 |
| caged amphibian tadpoles and in situ genotoxicity monitoring of aquatic environments with the alkaline single cell gel electrophoresis (comet) assay. | in previous studies we demonstrated that indigenous amphibian tadpoles are suitable organisms for monitoring small bodies of water (e.g., creeks, ponds, and drainage ditches) using the alkaline single cell gel electrophoresis (scg) or 'comet' assay. this approach involves detection, under alkaline conditions, of cell dna fragments which on electrophoresis migrate from the nuclear core, resulting in a 'comet with tail' formation. however, although often plentiful, tadpoles are not present in all ... | 1998 | 9651536 |
| physicians' attire as perceived by young children and their parents: the myth of the white coat syndrome. | to determine if young children have a preference regarding whether physicians do or do not wear a white coat. | 1998 | 9655662 |
| an association between the common hereditary hemochromatosis mutation and the factor v leiden allele in a population with thrombosis. | 1998 | 9694741 | |
| home care quality management. where are we now? where do we go from here? | this article is the first of a series of three focusing on key management processes in home care--quality management, financial and information management, and, service and human resource management. the articles examine the current state of practice in ontario and suggest a desirable future state. in this first article, home care is defined and a brief description is provided from a national and provincial perspective. quality is also defined and the drivers for quality in home care outlined. u ... | 1998 | 9726177 |
| north american liver fluke (metorchis conjunctus) in a canadian aboriginal population: a submerging human pathogen? | 1998 | 9735521 | |
| halicephalobus gingivalis (stefanski, 1954) from a fatal infection in a horse in ontario, canada with comments on the validity of h. deletrix and a review of the genus. | although the original description given by stefanski (1954) was satisfactory, anderson & bemrick (1965), in describing h. deletrix (= micronema deletrix), claimed stefanski's description was "inadequate" and the species a "species inquirenda". thus, infections in horses and humans have been assigned to h. deletrix. we believe the species reported in horses and humans is h. gingivalis and that h. deletrix is its synonym. h. gingivalis is separated herein from forms found free-living. the genital ... | 1998 | 9772725 |
| g protein beta3 subunit gene variant and blood pressure variation in canadian oji-cree. | the subunits of the heterotrimeric g proteins are attractive candidate gene products for both susceptibility to essential hypertension and interindividual variation in blood pressure. there is alternative splicing of exon 9 of the gene encoding the beta3 subunit of heterotrimeric g proteins (gnb3) associated with a c-->t change at nucleotide 825, which activates a cryptic splice site. the 825t allele results in a gene product that is 41 amino acids smaller than the wild-type gene product. g prot ... | 1998 | 9774364 |
| twenty-five years of surveillance for contaminants in human breast milk. | to monitor the exposure of canadian populations, health canada has carried out six major surveys of breast milk contaminants, beginning in 1967. in these national surveys, breast milk was collected from nursing mothers at various times in their nursing period, and the concentrations of chlorinated hydrocarbons were measured. there was a downward trend from 1967 to 1992, in the concentrations of organochlorine (oc) pesticides and polychorinated biphenyl hydrocarbons (pcbs). this regression was ob ... | 1998 | 9776790 |
| population genetic characteristics of the str loci d21s11 and fga in eight diverse human populations. | a highly polymorphic multiplex short tandem repeat (str) system composed of d21s11, fga, and the sex-typing system amelogenin (amg) has been used to investigate allele frequency distributions in two canadian caucasian samples (british columbia and alberta), three canadian aboriginal populations (coastal salishans from british columbia, ojibwa from northern ontario, and cree from saskatchewan), and three ethnic groups from singapore (chinese, malays, and asian indians). using the automated fluore ... | 1998 | 9780514 |
| psychological outcomes following maternal serum screening: a cohort study. | maternal serum screening is used to assist in the prenatal detection of congenital anomalies. its use is controversial, and one concern that has been expressed is its psychological effects on women. the authors examined whether this test leads to an increase in anxiety and depression among women who have a false-positive result as compared with those who have a true-negative result or do not undergo testing. | 1998 | 9780964 |
| the cost-effectiveness of routine pathology consultation in knee arthroscopy. | regulations in ontario, canada, as in most provinces and states in north america, require human tissues (with few exceptions) removed at surgery to be sent to a pathology laboratory for examination and report. we hypothesized that this practice is inconsistently followed and that routine pathological consultation is costly and rarely results in a change in treatment for patients undergoing knee arthroscopy. chiefs of pathology, orthopaedic surgeons, and orthopaedic operating room nurse managers ... | 1998 | 9788364 |
| prevalence of upper extremity symptoms and possible risk factors in workers handling paper currency. | the prevalence of upper extremity symptoms in the workforce is high, particularly in industries characterized by forceful, repetitive or awkward movements. a study was undertaken to assess the prevalence of upper extremity symptoms in bank workers in a paper currency processing operation and to examine the role of possible risk factors for these complaints. thirty-nine workers of a total workforce of 47 were assessed with a questionnaire and physical examination. the questionnaire collected info ... | 1998 | 9800421 |
| a single-primer pcr-based retroviral-related dna polymorphism shared by two distinct human populations. | almost 10% of the human genome consists of dna sequences that share homology with retroviruses. these sequences, which represent a stable component of the human genome (although some may retain the ability to transpose), remain poorly understood. we used degenerate primers specific to the two conserved regions (boxes 4 and 5) of the retroviral pol gene, common to all retroviruses, and pcr-amplified related sequences from individuals representing two distinct populations: caucasians and dogrib in ... | 1998 | 9809437 |
| variation in the au(at)-rich element within the 3'-untranslated region of ppp1r3 is associated with variation in plasma glucose in aboriginal canadians. | we are investigating associations between variations in candidate genes on chromosome 7q and diabetes-related phenotypes in canadian oji-cree. one of these genes encodes the skeletal muscle regulatory g subunit of the glycogen-associated form of protein phosphatase 1 (pppir3), which may play a key role in muscle glycogen metabolism. there is a common 5-bp insertion-deletion polymorphism in a messenger ribonucleic acid-stabilizing au(at)-rich element within the 3'-untranslated region (utr) of ppp ... | 1998 | 9814479 |
| safe drinking water: a public health challenge. | disinfection of drinking water through processes including filtration and chlorination was one of the major achievements of public health, beginning in the late 1800s and the early 1900s. chloroform and other chlorination disinfection by-products (cbps) in drinking water were first reported in 1974. chloroform and several other cbps are known to cause cancer in experimental animals, and there is growing epidemiologic evidence of a causal role for cbps in human cancer, particularly for bladder ca ... | 1998 | 9820833 |
| survey of canadian human blood plasma for ochratoxin a. | blood plasma samples collected from 144 healthy volunteers in 16 locations across canada in 1994 were analysed for ochratoxin a (ota). the method of analysis included cleanup by c18 solid phase extraction and immunoaffinity columns followed by liquid chromatography (lc) with fluorescence detection, which gave 86.5% (s.d. = 9.7) recovery (n = 31) of ota (added at 2 ng/ml) with a detection limit of 0.15 ng/ml. the arithmetic mean concentration found in the plasma samples, corrected for volume of a ... | 1998 | 9829040 |
| the economic costs of illicit drug use in ontario, 1992. | the use of illicit drugs causes health and social problems which imply economic costs to society. this paper uses the cost-of-illness method, in particular, the human-capital approach to estimate the prevalence-based economic costs of illicit drug use in ontario in 1992. this methodology is consistent with international guidelines formulated at the 1994 international symposium on economic and social costs of substance abuse. the economic cost of illicit drug use is estimated at $489.29 million ( ... | 1998 | 9541086 |
| human isolates of salmonella typhimurium dt104 in ontario. | 1998 | 9553281 | |
| etiology of acute childhood encephalitis at the hospital for sick children, toronto, 1994-1995. | of 145 patients admitted to our hospital because of encephalitis-like illness, 50 patients hospitalized for > or =72 hours underwent standardized microbiological investigations. a confirmed or probable etiologic agent was identified in 20 cases (40%), including mycoplasma pneumoniae (9 cases). m. pneumoniae and enterovirus (2), herpes simplex virus (4), epstein-barr virus (1), human herpes-virus 6 (hhv-6) (1), hhv-6 and influenza virus type a (1), influenza virus type a (1), and powassan virus ( ... | 1998 | 9502462 |
| two quantitative methods for rib seriation in human skeletal remains. | accurate rib sequencing is of importance to both forensic anthropologists and human osteologists, but until recently there have been few traits used to aid in the seriation of ribs within a human burial. this study examines two measurements (head to tubercle length and superior costotransverse ligament crest height) for the purpose of aiding rib identification and seriation in human skeletal remains. a sample of 344 ribs from 43 individuals from the 19th century anglican church cemetery of st. t ... | 1998 | 9456539 |
| provision of preventive care to unannounced standardized patients. | to examine the relation between physician, training and practice characteristics and the provision of preventive care as described in the guidelines of the canadian task force on the periodic health examination. | 1998 | 9469139 |
| what factors influence primary care physicians' charges for their services? an exploratory study using standardized patients. | to determine the extent of variation in physicians' charges for health care encounters with unannounced standardized patients and factors associated with the variation. | 1998 | 9469140 |
| trials sponsored by drug companies: review ordered. | 1998 | 11645095 | |
| evaluation of a cold/flu self-care public education campaign. | the purpose of the study was to evaluate an ontario ministry of health (moh) cold/flu self-care public education campaign to reduce unnecessary patient visits to doctors. the moh campaign consisted of an information booklet delivered to every household in an ontario city, newspaper ads and radio spots. the program ran during january-march 1994. the evaluation consisted of: (1) 2x2 telephone survey in london (experimental area) and windsor (comparison area), before and during the campaign; and (2 ... | 1998 | 10178337 |
| elder abuse and one community's response. | elder abuse has come to be recognized as any act of both commission or omission that causes harm or loss to elderly people. this can include active or passive neglect, violence, sexual or emotional abuse, various kinds of theft, and deprivation of the person's human rights. elder abuse has many causes. the hastings and prince edward council on aging developed an elder abuse community response protocol to help address this problem. | 1998 | 10185311 |
| learning to support your work force in changing times. | this article looks at how one health care organization, the royal ottawa health care group, has taken a proactive approach to the human resource challenges associated with ongoing changes and transitions in the work place. the overriding objective has been to retain a stable, highly skilled and motivated work force, which is essential to providing quality care. | 1998 | 10187661 |
| canadian panel calls for review of drug-trial confidentiality agreements. | 1998 | 11656958 | |
| consensus-seeking roundtable on placebos in clinical research. | 1998 | 15468464 | |
| gender and income in pharmacy: human capital and gender stratification theories revisited. | this is a case study of gender and earnings in pharmacy--a profession characterized by its rapid recruitment of female practitioners. we try to account for disparities in earnings between male and female pharmacists in ontario with the aid of human capital theory and gender stratification theory. data is drawn from a random sample of 463 ontario pharmacists. we find a consistent sex gap in earnings regardless of occupational level of practitioners (i.e. owner, manager or employee) and net of suc ... | 1999 | 15266676 |
| george fulford and victorian patent medicine men: quack mercenaries or smilesian entrepreneurs? | in the early twentieth century, a time when patent medicine men were stereotyped as evil and dishonest, g. t. fulford of brockville, ontario made his fortune from an iron pill called dr. williams' pink pills for pale people. once successful, fulford remained in brockville where he served on the town council and gave generously to charities. in 1900 he was appointed by laurier to the senate. when he died in 1905 he was remembered as a kind and ethical man. his story, like that of several other pr ... | 1999 | 14531402 |
| criminalization of assisted suicide challenged. | in september 1999, jim wakeford, a toronto man with hiv/aids, launched a civil action against the attorney general of canada, challenging the constitutionality of sections of the criminal code that criminalize assisted suicide. | 1999 | 11868549 |
| allegations of hiv infection raised in criminal trial of escort agency owner. | at the beginning of october 1999, a toronto man who owned an escort agency went to trial in the ontario superior court of justice on numerous charges of living off the avails of prostitution and procuring for the purpose of prostitution. on the first day of trial, the prosecutor indicated he would be introducing evidence suggesting that three of the women who worked as escorts for mark lucacko's agency may be hiv-positive. | 1999 | 11868553 |
| legal, ethical, and human rights issues facing east and southeast asian-canadians. | in the last issue of the newsletter, we reported about a project on hiv/aids and discrimination in south asian communities in canada, undertaken by the toronto-based alliance for south asian aids prevention (asap). in this issue, we report about another project focusing on issues of discrimination in ethnocultural communities in canada: a project on legal, ethical, and human rights issues facing east and southeast asian-canadians, undertaken by a toronto-based aids-service organization, the asia ... | 1999 | 11868556 |
| newman's theory of health applied in family caregiving in canada. | this study was conducted using an innovative mode of heuristic inquiry within the context of newman's theory of health as expanding consciousness. twelve caregiving families of persons who were diagnosed with schizophrenia participated in the study. in accordance with newman's theory of health as praxis, the majority of the participants in the study recognized their patterns of the whole. as a result, they reported understanding and acceptance of their relative's mental illness. | 1999 | 11847656 |
| human resource issues: a comparison by region. | 1999 | 10635151 | |
| determining ontario's supply and requirements for ophthalmologists in 2000 and 2005: 1. methods. | we performed a study to determine the supply of and requirements for ophthalmologists in ontario in 2000 and 2005. in this paper we describe our methods. | 1999 | 10321317 |
| morbidity and mortality related to human immunodeficiency virus in canadian men and women, 1987-94. | to assess the impact of hiv/aids on hospitalization and mortality patterns in canada. | 1999 | 10349221 |
| temporal and geographical distributions of reported cases of escherichia coli o157:h7 infection in ontario. | the distribution of 3001 cases of verocytotoxigenic escherichia coli (vtec) reported in the province of ontario, canada, were examined to describe the magnitude of this condition geographically and to evaluate the spatial relationship between livestock density and human vtec incidence using a geographical information system. incidence of vtec cases had a marked seasonal pattern with peaks in july. areas with a relatively high incidence of vtec cases were situated predominantly in areas of mixed ... | 1999 | 10355782 |
| the urology work force in ontario for the 21st century: feast or famine? | to address the issues of work-force planning and modelling in the 21st century for the specialty of urology in the province of ontario. | 1999 | 10372014 |
| cold/flu knowledge, attitudes and health care practices: results of a two-city telephone survey. | the purpose of this paper is to describe knowledge, attitudes and practices of cold and flu self-care and health care utilization, and to identify the predictors of health care utilization for the cold and flu among residents of london and windsor. using a random digit dialing survey method, 417 residents were interviewed between november-december, 1993 and february-march, 1994. this survey revealed good knowledge about colds and flu and understanding of appropriate physician visits. only seven ... | 1999 | 10401174 |