Publications

properties of the enterotoxic component in escherichia coli enteropathogenic for swine.	the enterotoxic component in sterile syncase broth filtrates of escherichia coli strains 340 (o9:k.:nm) and p307 (o8:k87,88a,b:h19) was studied. the enterotoxic activity in both strains was retained by an ultrafiltration membrane with a molecular weight retention of 100,000 (xm-100a) and eluted from a sephadex g-200 column in the void volume. the enterotoxic activity in strain 340 was resistant to heating at 75 c for 30 min, but the activity in strain p307 was destroyed by heating at 60 c for 30 ...	1973	4633289
the production of ige and igg1 antibodies in guinea-pigs immunized with antigen and bacterial lipopolysaccharides.		1973	4354826
entamoeba histolytica: concurrent irreversible loss of infectivity-pathogenicity and encystment potential after prolonged maintenance in axenic culture in vitro.		1973	4355413
[mesentary air vesicles. an interesting condition in veterinary examination of meat].		1973	4618932
experimental colibacillosis in gnotobiotic body pigs. ii. pathology.	sixty-two neonatal gnotobiotic pigs were used in three experiments to determine the lesions produced by two closely related strains of escherichia coli o138:k81:nm (of michigan origin) and o138:k81 (of minnesota origin). exposure was by subcutaneous injection of bacterial culture into the umbilical stump or by oral inoculation. gross signs common to monocontaminated pigs included distention of the flaccid small and large intestines with fluid contents. edema was prominent in various tissues of m ...	1973	4270434
immunochemical studies of escherichia coli succinic thiokinase. effects of sulfhydryl reagents and other treatments on the enzyme.		1973	4567789
the use of germ-free piglets in the study of lymphoid tissue and germinal centre formation.		1973	4137308
experimental edema disease of swine (e. coli enterotoxemia). i. dectection and preparation of an active principle.	freeze-thaw lysates prepared from strains of escherichia coli belonging to serogroups o138, o139, and o141 contained a principle (edema disease principle) which induced edema disease in swine. all freeze-thaw lysates contained endotoxic activity that tended to obscure the edema disease syndrome and methods were developed to reduce such activity. freeze-thaw lysates prepared from e. coli o139 induced the most characteristic edema disease syndrome. partially purified edema disease principle prepar ...	1974	4272954
experimental edema disease of swine (e. coli enterotoxemia). 3. pathology and pathogenesis.	experimental colibacillary (escherichia coli) enterotoxemia as described in this report mimics natural edema disease both clinically and in gross pathology. the histopathology is characterized by accumulations of non-inflammatory edema and by arteriopathy. the smaller arterial and arteriolar changes recorded here are similar to those described in natural edema disease. the vascular changes described in recovered cases of experimental colibacillary enterotoxemia concur with those reported in so-c ...	1974	4272956
[mercury and antibiotic resistance in "enterobacteriaceae." an experimental study on pigs (author's transl)].		1974	4619760
mutation in shigella flexneri resulting in loss of ability to penetrate hela cells and loss of glycerol kinase activity.	a colonial variant of a virulent shigella flexneri 2a has lost both virulence and glycerol kinase activity. it also has several other altered characteristics: lowered ability to oxidize tricarboxylic acid cycle intermediates, increased electrophoretic mobility, and decreased sensitivity to sodium lauryl sulfate. genetic analysis has revealed that the gene governing glycerol kinase activity in shigella has a different chromosomal locus than that from escherichia coli. furthermore, transduction of ...	1974	4363235
immunity to escherichia coli in pigs: igg and blood clearance.		1974	4133893
[comparative studies on the pathology and pathogenesis of spontaneous coli enterotoxemia and of the experimental coli endotoxin syndrome in swine. v. studies on the pathomorphology of the central nervous system in spontaneous coli enterotoxemia and the experimental coli endotoxin syndrome].		1974	4136319
peptic digestion of pig igm.		1974	4208583
[adjuvant activity of monomeric fractions of bacterial peptidoglycans in delayed hypersensitivity].		1974	4211288
[the effects of human-and animal-pathogenic coli strains on the isolated intestine of rabbit (author's transl)].		1974	4151208
transferable tetracycline resistance in salmonella cholerae-suis var. kunzendorf.		1974	4155891
minimum inhibitory concentration of furazolidone for e. coli and salmonella strains isolated in nigeria.		1974	4593537
protection of pigs against neonatal enteric colibacillosis with colostrum and milk from orally vaccinated sows.		1974	4594741
chemotaxis and cotton extracts.		1974	4594750
outbreaks of post weaning escherichia coli diarrhoea in pigs.		1974	4598696
occurrence and transfer of antibiotic resistance, colicinogeny and haemolysin production in escherichia coli strains isolated from cases of colibacillosis.		1974	4600128
binding of the elongation factors ef 1 and ef 2 to 80 s ribosomes in a cell-free system from porcine brain of the hypothalamic region.		1974	4604150
studies on polypeptide elongation factor 2 from pig liver. i. purification and properties.		1974	4607115
bacterial and biochemical studies on gamma-irradiated swine.		1974	4608071
binding of beta-galactosidase by cells from germfree colostrum-deprived piglets.		1974	4608372
conditions for the production of escherichia coli enterotoxin in a defined medium.		1974	4608426
an amino acid sequence in the active site of lipoamide dehydrogenase from pig heart.	1. the two cysteine residues forming the disulphide bridge that comprises part of the active site of lipoamide dehydrogenase from pig heart were specifically labelled with iodo[2-(14)c]acetic acid. 2. a tryptic peptide containing these carboxymethylcysteine residues was isolated from digests of reduced and s-carboxymethylated lipoamide dehydrogenase and its amino acid sequence of 23 residues was determined. 3. the sequence is highly homologous with a similar sequence containing the active-site d ...	1974	4608583
[incidence in industrial feed mixtures of e. coli o groups and their enteropathogenicity for pigs and virulence for mice].		1974	4610531
oral immunization against enteric infections using inactivated bacteria. a review.		1974	4613138
a possible basis for the breeding of pigs relatively resistant to neonatal diarrhoea.		1974	4615428
continuous non-therapeutic use of antibacterial drugs in feed and drug resistance of the gram-negative enteric florae of food-producing animals.	fecal samples from illinois farm animals and montana range cattle were examined for the frequency of gram-negative enteric organisms resistant to oxytetracycline, dihydrostreptomycin, or ampicillin. the illinois farm animals were continually fed rations containing various antibacterial drugs. the montana range cattle had minimal exposure to antibacterial drugs. the majority of samples from illinois farm animals demonstrated 10% or more antibiotic-resistant organisms. in contrast, resistant organ ...	1974	4615630
an attempt to identify the intestinal receptor for the k88 adhesin by means of a haemagglutination inhibition test using glycoproteins and fractions from sow colostrum.	the k88 antigen of escherichia coli specifically adheres to the piglet intestinal cell; a solution of this antigen agglutinates guinea-pig red cells at 4 degrees c. the latter reaction was used as a model of the former, using inhibition of haemagglutination as an index of specific combination with the k88 adhesin. inhibition was found with mucous glycoproteins and chemical modification of their heterosaccharide residues by mild acid hydrolysis, periodate oxidation or the smith degradation proced ...	1975	46271
mucosal adherence of human enteropathogenic escherichia coli.	an in-vitro assay system has been developed to measure bacterial adhesion to the mucosa of human fetal small intestine. two strains of escherichia coli that are proven human enteropathogens (e.p.e.c.) have been shown to adhere in large numbers, compared with control organisms. the attachment mechanism is species specific and is not caused by common fimbriae. mucosal adhesion may be as important as enterotoxin production or invasiveness in determining the virulence of some strains of human e.p.e. ...	1975	53431
comparison of the effect of various antisera and cobra venom factor on inflammatory reactions in guinea-pig skin. ii. the arthus reaction and the local shwartzman reaction.	the ability of antisera to guinea-pig c3 to inhibit the arthus and local shwartzman reactions was studied. they were found to reduce the non-haemorrhagic component of the active and reversed passive arthus reactions and to delay the appearance of the haemorrhage in the active arthus reaction. cobra venom factor, however, had no effect on the non-haemorrhagic components of these reactions and only delayed the appearance of the haemorrhage of the active arthus reaction. there appeared to be a corr ...	1975	125318
a cyclic adenosine 3',5'-monophosphate-dependent histone kinase from pig brain. purification and some properties of the enzyme.	a cyclic adenosine 3',5'-monophosphate-dependent histone kinase (atp: protein phosphotransferase, ec 2.7.1.37) was isolated from pig brain. the enzyme has been purified 1140-fold; it is homogeneous on polyacrylamide gel electrophoresis and gel filtration. the estimated molecular weight of the enzyme is 120 000. histone kinase dissociates into a catalytic subunit and a regulatory one (molecular weights 40 000 and 90 000, respectively). the catalytic subunit has been obtained in homogeneous state ...	1975	235302
the effect of antisera on porcine enteropathogenic escherichia coli in ligated segments of pig intestine.	nineteen antisera produced in pigs against 14 enteropathogenic and five nonenterotoxigenic porcine strains of escherichia coli were tested for their ability to inhibit gut loop fluid accumulation induced by homologous and heterologous organisms. in addition, four antisera produced in pigs by an intensive series of intravenous inoculations and three by a less intensive series of intramuscular injections of a polyvalent e. coli vaccine were evaluated. antisera were also produced in rabbits against ...	1975	1089462
[pathogenesis of toxin caused gastroenteritis of vibrios and coli bacteria].		1975	1089519
escherichia coli infections in piglets: pathogenesis, virulence and vaccination.		1975	1091085
[bacteriocinogeny in yersinia enterocolitica].	bacteriocinogeny was found in 19.8 per cent of y. enterocolitica strains tested. it was designated by the authors as enterocoliticacinogeny and the substance produced by the pathogen was named enterocoliticacine. bacteriocinogeny was found among the collection strains isolated in the south primorye and not among the strains isolated abroad. some cultures of y. enterocolitica isolated abroad and in the south primorye were used as indicator strains for revealing enterocoliticacinogeny. enterocolit ...	1975	1091204
enzymatic arginylation of beta-melanocyte-stimulating hormone and of angiotensin ii.	porcine beta-melanocyte-stimulating hormone and angiotensin ii were examined as acceptors in the reaction catalyzed by arginyl-trna-protein transferase. both inhibited enzymatic transfer of [14c]arginine from trna to bovine albumin. inhibition was competitive with albumin and the k-i values were, respectively, 15 and 0.8 mum. the expected arginylated compounds were isolated and characterized. beta-melanocyte-stimulating hormone and its arginylated product had identical activities in the frog epi ...	1975	1091639
the sequence of amino acid residues around the oxidation-reduction active disulfide in yeast glutathione reductase.	a 14-residue peptide containing the oxidation-reduction active cystine residue from yeast glutathione reductase has been isolated from proteolytic digests of the enzyme in which the free sulfhydryl groups had been reacted with n-ethylmaleimide. the sequence of this disulfide-containing peptide was found to be:(see article). the sequence was highly homologous with the active cystine regions in escherichia coli and pig heart lipoamide dehydrogenase. the sequences of three of the postulated four th ...	1975	1092678
some immunological aspects of liver function.		1975	1093339
preweaning mortality in pigs. 4 diseases of the gastrointestinal tract in pigs.	the incidence of fatal gastroenteropathies in sucking pigs was studied during a 2-year period in 17 sow herds involving 2,936 litters. the results showed that 2.8 per cent of the liveborn pigs died with gastroenteropathies during the sucking and immediate post weaning period. the incidence was lowest in offspring from second-litter sows (table i) and the progeny from large litters tended to have the highest incidence (table ii). fatal gastrointestinal diseases were observed in a total of 17.6 pe ...	1975	1094407
the in vitro and in vivo effects of carrageenin on humoral and cellular factors of natural resistance.	the inhibitory effect of carrageenin, a sulfated algal polygalactose, on humoral factors of natural resistance is discussed. in dependence on dose and time, the influence of non-specific and specific bacteriolysis, on the in vitro and in vivo opsonic activity and on the course of infection was studied.	1975	1095463
relationships of antibiotics in animal feeds and salmonellosis in animals and man.		1975	1095537
the effects of feeding tetracycline, nitrovin and quindoxin on the drug-resistance of coli-aerogenes bacteria from calves and pigs.		1975	1095540
[problems of resistance (author's transl)].	the results of sensitivity tests performed during the period from 1970 up to 1973 inclusive are compared with those obtained in pervious years. this showed that resistance to penicillin had increased in staphylococci causing bovine mastitis. during each single year, however, there was a decrease. s. typhimurium isolated from cattle showed increased resistance to chloramphenicol, neomycin and ampicillin; s. dublin showed an increase in resistance to chloramphenicol. e. coli isolated from calves w ...	1975	1096359
enteric colibacillosis: evaluation of strains of escherichia coli utilizing the ligated loop technique in gnotobiotic swine.	the enteropathogenicity of 6 strains of escherichia coli was evaluated via the ligated loop technique in 15 gnotobiotic swine 3 to 4 weeks old. strain enteropathogenicity in gnotobiotic swine, as determined on the basis of visual loop distention and light microscopic evaluation of intestinal sections, compared favorably with that reported in conventional swine, except that jejunal loops of gnotobiotic swine may be somewhat less sensitive to certain strains. in addition, postoperative mortality r ...	1975	1096688
heat-stable escherichia coli enterotoxin production in vivo.	hysterectomy-derived, colostrum-deprived piglets were infected with enterotoxigenic escherichia coli on day 4 of life. samples of feces and intestinal contents were collected and tested in infant mice for enterotoxic activity. positive enterotoxic responses were observed in mice given filtrates of feces and intestinal contents from piglets infected withe enterotoxigenic e. coli known to produce heat-stable enterotoxin but not heat-liabile enterotoxin in vitro. it is concluded that heat-stable en ...	1975	1097335
a field study of coliform mastitis in sows.	three sows with agalactia and mastitis were compared with 3 normally lactating sows at 8, 16, 24, and 32 hours postpartum. bacteriologic examination of milk resulted in isolation of klebsiella pneumoniae or escherichia coli from affected glands of all 3 agalactic sows. milk from clinically normal glands of affected sows and from glands of normal sows was culture-negative for coliforms. affected sows had higher rectal temperatures and lower milk yields, and pigs from affected sows had lower mean ...	1975	1097381
in vitro study of the influence of virginiamycin and spiramycin on the composition and biochemical activities of the gastrointestinal flora of piglets. i. influence on the composition of the flora.	in vitro fermentations with the gastro-intestinal flora of 18 treated piglets (control, virginiamycin, spiramycin) were carried out to study the influence of nutritional doses of virginiamycin and spiramycin on the composition of the microflora. each total flora was used for three different incubations: control, 50 ppm virginiamycin, 50 ppm spiramycin. to obtain comparable results with experiments in vivo, an artificial fermentation medium was made on the basis of several chemical analyses of in ...	1975	1098325
factors involved in bactericidal activity of sheep serum.	the bactericidal activity of blood, plasma, and serum from sheep was measured with 3 strains of escherichia coli. plasma showed greater bactericidal activity than blood or serum for strains o78:k80(b) and lilly. the antibody-complement system of normal serum killed the rough strain, lilly, but neither antibody nor complement alone were bactericidal. antibody, complement, and an additional heat-stable cofactor were necessary for killing strain o78:k80(b). strain 3662 was not susceptible to the le ...	1975	1098531
relationships of intestinal enzymes and serum antitoxin to the pig response to escherichia coli enterotoxin.	the intestinal loop technique was used to evaluate the response of three week old piglets to the heat labile (lt) and the heat stable (st) enterotoxins produced by escherichia coli f11(p155). the serum anti-lt activity and the lipase, amylase and trypsin activities in the jejunal lumen of these pigs were determined. piglets responded independently ti each toxin and no relationship between these responses and serum anti-lt activity or the enzyme activities of the jejunal content could be demonstr ...	1975	1100203
[goblet cells in spontaneous colibacteriosis in pigs].	this work is a part of the studies on the intestinal barrier undertaken to cast some more light on the pathogenesis of colibacteriosis in pigs. the objective of the work was to investigate the goblet cells in the intestines of pigs ill with spontaneous colibacteriosis in the form of oedema disease and gastrointestinal form. the investigations were carried out on 26 pigs segregated into 3 groups: i group -- typical oedema disease (12 pigs), ii group -- colibacteriosis in the gastrointestinal form ...	1975	1101236
leptospirae of serotype lora of the serogroup australis isolated for the first time from swine in the netherlands.	leptospirosis in swine, caused by serotype lora (serogroup australis) was detected both serologically and by culture. the most important symptoms consisted in abortion during the final month of gestation and the birth of dead or not viable piglets.	1975	1101443
[the infectious (plasmidic) bacterial antibiotic resistance].		1975	1102479
[course of beta-hemolytic e. coli carrier state in piglets during weaning].	the investigations were carried out on 22 sows and 44 piglets (one sow and 2 piglets from each litter). the pigs were divided into 4 groups according to the different additions to their diet during weaning which might have an effect on the carrier state and dissemination of beta-haemolytic e. coli. group i was given a feed concentrate and separated milk, group ii - a feed concentrate and sour milk, group iii - a feed concentrate and milk with addition of garlic (200 mg/kg of body weight), group ...	1975	1103097
the role of immune pig colostrum, serum and immunoglobulins igg, igm, and iga, in local intestinal immunity against enterotoxic strain in escherichia coli o55 in germfree piglets.	the protective effect of pig immune colostrum, serum and immunoglobulins igg, igm and iga against the enterotoxic strain of escherichia coli o55, was studied in newborn germfree piglets. this strain produced accumulation of fluid and dilatation of intestine when injected into the ligated ileal segment of germfree piglets, which is considered to be the typical effect of enterotoxins. erosion of the intestinal epithelium and penetration of bacteria into the submucosa were also observed. immune ser ...	1975	1104425
localization of rate-limiting barrier to penetration of endotoxin through nonkeratinized oral mucosa in vitro.	the penetration of tritiated bacterial endotoxin through nonkeratinized oral mucosal epithelium was studied using an in vitro model system and radioautographic tracer techniques. the basement membrane region of the epithelium was the rate-limiting barrier to penetration, and this barrier effect was independent of the direction and duration of penetration as well as any clearance effects of the vasculature.	1975	1104674
[serotype 185 and e. coli o115 - two distinct bioseropathotypes (author's transl)].	e. coli o115 strain 27w and trabulsi's serotype 185 have been subjected by us to comparing examinations of the serological behaviour of their cell wall and their protoplasmatic antigens, of their biochemical and cultural behaviour and their pathogenicity for the mucous membranes of guinea-pigs. as a result of this inquiry it was found, that e. coli o115 27w and the dysentery-provoking serotype 185 are biological distinct bacteria which only share a minor cross relationship of their o-antigens, a ...	1975	1106060
[protective oral immunization against coli enterotoxemia in swine (author's tranls)].	the issue of immunity in the case of enteric infections caused by bacteria is still widely unresolved. to clarify this, weaned piglets 6-7 weeks of age were used as a model, because of the particular susceptibility to colienterotoxemia shown by them at this particular age. the experimental design was as follows. the animals were immunized orally and parenterally (i.v. and i.p. routes) by means of a vaccine consisting of bacteria incapable of reproduction. 14 days later, the animals were challeng ...	1975	1106063
[diagnosis of edema disease (colienterotoxemia) in piglets].		1975	1108384
the etiology of swine dysentery. iii. the role of selected gram-negative obligate anaerobes.	a disease resembling swinee dysentery occurred in gnotobiotic piglets previously colonized with escherichia coli and given a mixture of five enteric anaerobes and spirochete b-78, orally. no disease occurred in germ-free piglets exposed to four gram-negative obligate anaerobes or to the spirochete; however, if the four respective anaerobes were introduced into gnotobiotic pigs previously colonized with the spirochete, or when the spirochete was introduced into gnotobiotic pigs colonized with the ...	1975	1167199
[study of the role of colicins in the formation of microbial association in experiments in chick embryos].	experiments were conducted on chick embryos; conditions of formation of bacterial cenosis of shigella sonnei and e. coli were reproduced. the role of colicinogenia in the formation of bacterial cenosis was demonstrated. an accumulation of colicines in high titres (1: 5120- 1:2560) in the chick embryonic cavity was noted in combined or separate cultivation of colicinogenic shigellae and e. coli. an intergenera transmission of the col-factor was traced in experiments on chick embryos. the data obt ...	1975	766520
[changes in the virulence of colibacteria under the influence of various biological factors].		1975	766580
the pathogenesis of reflux nephropathy (chronic atrophic pyelonephritis).	the relationship between vesico-ureteric reflux and coarse renal scarring (atrophic pyelonephritis) has been studied in swine. scars were observed to develop where reflux took place into the kidney substance via the renal papillae (intrarenal reflux). they were confined to these regions and were similar in size, distribution and other features peculiar to those found in the human from early childhood onwards. intrarenal reflux was found to be related to the pressure within the urinary tract as ...	1975	766885
[the role of environmental pollution in the etiology of endemic nephropathy].		1975	785634
[actinomycin do inhibition of rna biosynthesis and its interaction with dna preparations].	actinomycin d0 differing from actinomycin d in replacement of i residue of sarcosine by glycine in one of the peptide chains was found to have a lower inhibitory effect on rna synthesis in various biological systems. on interaction of e. coli with dna actinomycin d0 formed a complex with dna having the binding constant k=1.6 with 10-5 which was 100 times lower than the binding constant of actinomycin d. therefore, actinomycin d0 formed a complex with dna which was 100 times less stable than acti ...	1975	806255
in vitro study of the influence of virginiamycin and spiramycin on the composition and biochemical activities of the gastrointestinal flora of piglets. ii. influence on the biochemical activities of the microflora.	chemical analysis was carried out on 54 in vitro fermentations to study the influence of nutritional doses of virginiamycin and spiramycin on the metabolic activity of the gastro-intestinal flora of 18 in vivo treated piglets. changes in the decomposition of glucose and the production of nh3, volatile acids and lactic acid are recorded in function of time. these results are in good accordance with changes noted in the composition of the bacterial flora, such as a marked decrease in the productio ...	1975	808048
[false-positive results obtained on examining slaughtered animals for the presence of antibiotic residues (author's transl)].	as part of the examination of emergency-slaughtered animals for the presence of antibiotic residues, studies were done to see whether false-positive results would be obtained when the sarcina lutea kidney test and bacillus subtilis bga test were performed. when the s. lutea kidney test was positive in cattle, calves and swine, penicillin was invariably found to be present in those animals, the histories of which showed that they had not been given antibiotics. a syringe and an injected fluid con ...	1975	809859
the in vivo opsonizing activity of fab mu and f(c)5 mu fragments of pig immunoglobulin m to escherichia coli 0 55 in newborn, precolostral piglets.		1975	812799
interference by neisseria gonorrhoeae growth by other bacterial species.	growth of neisseria gonorrhoeae from clinical specimens has been enhanced by the use of selective media that inhibit the simultaneous growth of other microorganisms. one explanation for this enhancement could be that certain other bacteria inhibit gonococcal growth. this hypothesis was examined by testing 167 bacterial isolates for in vitro gonococcal inhibition; 34.1% of the isolates failed to inhibit the gonococcus, but 12.0% produced weak inhibition and 53.9% strongly inhibited n. gonorrhoeae ...	1976	823175
[the effect of furazolidone or carbadox in the starter mixture for early-weaned piglets].	for a period of 14 days, piglets from six litters, weaned between the 25th and 28th day of age, were fed the cos 2 starter containing either a premix with furazolidone or carboadox of czechoslovak origin. bentonite hydrosilicate was used as a carrier in both cases. furazolidone administered in the dose of 200 mg per 1 kg of feed prevented diarrhoea, insignificantly increased body weight gain, and decreased the consumption of feed per 1 kg of gain from 5.6 kg in the control to 4.0 kg in the test ...	1976	828986
etiologic diagnosis of diarrheal disease of calves: frequency and methods for detecting enterotoxin and k99 antigen production by escherichia cola.	escherichia coli isolated from calves in minnesota and montana were tested for enterotoxigenicity via bio-assay of cell-free broth culture fluid and for k99 antigen via a serum agglutination test. infant mice were used to assay for heat-stable enterotoxin (st), and adrenal cells in culture were used to assay for heat-labile enterotoxin (lt). forty-six of the 345 e coli isolates produced st enterotoxin, but none produced lt enterotoxin. thirty-five of the 46 enterotoxigenic isolates had k99 antig ...	1976	786085
[change in the virulence of flexner shigellae following transmission of several parts of chromosomes related to the synthesis of o-antigen lipopolysaccharide from e coli k-12 and r-mutants of shigellae].		1976	790821
[chemotherapeutic efficiency of olaquindex in experimental e.coli-diarrhea and enterotoxaemia of piglets].		1976	793001
escherichia coli strains isolated from diarrheic piglets in the province of quebec.	during 1972 to 1974, 112 escherichia coli strains isolated from diarrheic piglets were recieved from different parts of the province of quebec, canada. fifty-six strains elicited a positive gut loop response in three week old piglets and were then considered as moon's class 1 enteropathogens, while four of the 56 remaining strains reacted only in ten day old piglets and were classified as class 2 enteropathogens. forty-eight strains produced both a heat-labile and a heat-stable enterotoxin, whil ...	1976	793691
characterization of enterotoxigenic bovine escherichia coli.	among 300 isolates of bovine escherichia coli, 56 which had been found enterotoxigenic in calf gut loops were characterized on the basis of o and k antigens, colonial morphology and resistance to seven antimicrobial drugs. the 56 isolates enterotoxigenic in the calf were compared with the nonenterotoxigenic ones. of the 56 enterotoxigenic e. coli the majority possessed the a type of k antigen and had ok groups, o9:k(ps274) or o101:k(rvc118). fourteen of these isolates had the k99 antigen. none o ...	1976	793694
the mutagenicity of cyclamates and their metabolites.		1976	796692
[drug resistance and virulence of citrobacter isolated from the focus of piglet intoxication].		1976	797596
[experimental studies on the pathogenesis of coli enterotoxemia in swine. 3. effect of coli enterotoxin in weaned piglets following intragastric administration].	the following results were obtained from experiments with 23 clinically intact weaned piglets, aged between five and six weeks (18 animals) or eight weeks (five animals), which had received three intragastric applications of crude enterotoxin (culture filtrate supernatant of escherichia coli o149:k91(b)k88(l):. 1. twelve animals (52 per cent) responded to enterotoxin application by temporary outbreaks of diarrhoea (1-8.5 hours) following differentiated latencies (2.5-10 hours). no diarrhoea was ...	1976	798558
[effect of acetylsalicylic acid on experimentally induced endotoxin reactions in swine].	the time and severity of clinical responses to endotoxin depend on dosage, administration of acetylsalicyclic acid and indometacin prior to endotoxin application may delay or moderate the clinical phenomena that are likely to result from certain endotoxin amounts.	1976	798559
[e. coli enterotoxicosis in unweaned piglets. i. some concepts (author's transl)].	in a brief review, attention is drawn to a number of findings on infections with enteropathogenic e. coli in suckling piglets: serological typinge k88 antigen, colonisation, enterotoxin production and enterosorption, absence of symptoms of inflammation in the bowel wall and significance of the various immunoglobulin classes. the term e. coli enterotoxicosis used to designate the disease is preferred to terms such as e. coli diarrhoea, e. coli enteritis and (enterotoxic) colibacillosis.	1976	772876
[e. coli enterotoxicosis in unweaned piglets. iii. preparation and use of vaccines in enterotoxaemia due to e. coli in newborn piglets in the netherlands].	the preparation of a number of e. coli vaccines designed to prevent enterotoxicosis due to e. coli in young piglets is discussed. the results of laboratory experiments concerned with the production of haemagglutinating antibodies in pigs following inoculation of this vaccine are reported. this oil-adjuvant vaccine (oav) was used in the field in thirty-one herds in which enterotoxicosis due to e. coli was a recurrent problem. it is concluded from serological and clinical observations that the use ...	1976	772878
[e. coli enterotoxicosis in unweaned piglets. iv. evaluation of results obtained on using an adjuvant vaccine in the field (author's transl)].	the results obtained on using an adjuvant vaccine against enterotoxaemia caused by e. coli in suckling piglets are discussed on the basis of an inquiry conducted among a number of veterinary practitioners. the vaccine contains the ok groups o138:k81,k88, o141:k85ab and o149:k91,k88 and is administered parenterally to the dams during the latter half of gestation. the inquiry which covered 4,000 sows on fifty-five farms showed that, as regards diarrhoea during the first week of life, morbidity in ...	1976	772879
proceedings: polypeptide chain elongation in bacterial and mammalian systems.		1976	776955
isolation and metabolism cage system for newborn pigs.	an isolation system was designed and constructed for isolating normal and infected newborn pigs. the system consisted of an outer cage fitted with a biological diffusion filter and a dunk bath entry system and an inner metabolism cage to contain the pig. when tested with s-13 bacteriophage, the isolation and metabolism cage system was at least 99% efficient in preventing the entry or escape of microorganism. a total of 267 escherichia coli-infected newborn pigs have been isolated in these units, ...	1976	1259227
the occurrence of salmonellas, mycobacteria and pathogenic strains of escherichia coli in pig slurry.	ninety-eight samples of pig slurry from 54 farms were examined for the presence of salmonellas, porcine enteropathogenic strains of haemolytic escherichia coli and mycobacteria. salmonellas were isolated from 12 farms (22%) and enteropathogenic e. coli from 13 farms (24%). pathogenic mycobacteria were not isolated. salmonellas were isolated from 7 of 16 farms (44%) stocked with 'minimal disease' pigs compared with only 5 of 38 farms (13%) stocked with conventionally reared pigs. conversely enter ...	1976	10332
[residues of antimicrobial materials in the effluents of livestock farms (author's transl)].	forty water samples were taken from streams of three different regions of belgium, with intensive husbandry and examined for residual microbiological activity. in some samples, activity was detected against staphylococcus aureus; none of them were active against e. coli and c. albicans. the substances in the few positive samples were not identified. with this low activity and the small proportion of positive samples (12 out of 41) any influence on the water biosphere due to the methods of farmin ...	1976	766304
clinical uses of kanamycin, neomycin and streptomycin.		1977	73127
[influence of cleansing and disinfection of drinking troughs on germ content and coli titer of drinking water].		1977	319787
occurrence of k99 antigen on escherichia coli isolated from pigs and colonization of pig ileum by k99+ enterotoxigenic e. coli from calves and pigs.	several strains of enterotoxigenic escherichia coli (etec) isolated from pigs were found to have an antigen (k99) previously reported only on strains of calf and lamb origin and which facilitates intestinal colonization in the latter two species. several human etec were also tested for k99; however, none were positive. each of four k99-positive etec strains of calf origin and one of pig origin produced k99 in pig ileum in vivo, adhered to villous epithelium in pig ileum, colonized pig ileum, and ...	1977	321356
[coagulation analytical studies in coli enterotoxemia in swine].	store pigs with spontaneous outbreaks and experimental endotoxin shock were kept under observation in the context of coagulation analysis. heparin was applied to some of the animals to disrupt the plasmatic coagulation system. the thrombocyte count in animals with endotoxin infusion declined by some 50 to 65 percent of the original level. no statistically secured difference was found to exist between heparinised animals, on the one hand, and non-heparinised, on the other. the aggregation and adh ...	1977	322631
colonization of porcine small intestine by escherichia coli: colonization and adhesion factors of pig enteropathogens that lack k88.	the colonizing and adhesive attributes of enterotoxigenic acapsular and/or nonpiliated mutants from k88-negative enteropathogenic escherichia coli strains were compared with their capsulated and piliated parents (parents were piliated when grown in vitro and in vivo). acapsular, nonpiliated mutants from three different colonizing strains of enteropathogenic e. coli lost their ability to colonize the ileum of newborn pigs. acapsular, piliated and capsular, nonpiliated mutants were derived from on ...	1977	323375
[comparative study of the virulence of enteropathogenic intestinal bacilli 0124 and crimea].		1977	325332
interactions of radio-detoxified escherichia coli endotoxin preparations with the complement system.	escherichia coli o89 lipopolysaccharide (lps) was treated with different doses of gamma irradiation (5, 10, 15, and 20 mrad). various biological activities such as lethal effect, decrease in arterial blood pressure in dogs, and interaction with the complement system were determined for the parent and irradiated preparations. irradiation of lps significantly and in a dose-dependent manner decreased its lethal and blood pressure-depressing effects along with its ability to activate the complement ...	1977	326671
reduction of reactivity of escherichia coli enterotoxins by intestinal mucosal components.	incubation studies involving rabbit and piglet small intestinal mucosal components and escherichia coli and vibrio cholerae enterotoxins were conducted at 37 and 4 degrees c. mucosal homogenate cytosol from rabbits did not significantly alter the reactivities of either cholera enterotoxin (ct) or e. coli labile enterotoxin (lt). however, mucosal homogenate cytosol from piglets was capable of neutralizing lt, though it had no effect on e. coli stable enterotoxin. lt became bound to piglet and rab ...	1977	326677
r-factor-mediated antibiotic resistance in e. coli strains isolated from piglets in sweden.	e. coli strains, isolated from piglets over the periods 1964-1968 and 1974-1975, were investigated and compared with respect to antibiotic resistance. the frequency of monoresistant strains decreased from 50% in 1964-68 to 27% in 1974-75, while that of strains showing double or multiple resistance increased from 13% to 22%. the proportions of the different resistance determinants were as follows (figures for 1964-68 within parentheses): tetracycline 23% (49%), sulphaisodimidine 38% (24%), strept ...	1977	329617
a microbiological study of gastro-enteritis in black infants.	a survey was carried out to determine the aetiological agents responsible for acute gastro-enteritis in black infants. bacteriological examination of 191 patients and 178 age-matched controls showed that salmonellae and shigellae together accounted for only 15% of cases and were harboured by almost 7% of controls. seropositive 'enteropathogenic' escherichia coli was an important cause of diarrhoea, especially in the summer months. enterotoxin-producing e. coli was not a significant cause of gast ...	1977	331509